This is a non-core endpoint: only basic statistics are computed.
See these related core endpoints for full statistics:
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
1 out of 7 registries used, show all original rules. |
1232 |
4. Check minimum number of events
Min. number of events
3
|
1232 |
5. Include endpointsNone |
1232 |
6. Filter based on genotype QC (FinnGen only) |
1232 |
Control definitions (FinnGen only)
- Control exclude
- IBD_DRUGS
Extra metadata
- First used in FinnGen datafreeze
- DF4
Similar endpoints
↥List of similar endpoints to
6-mercaptopurine
based on the number of shared cases.
Similar with more cases:
- Second line medication for Crohn's disease
- Inflammatory bowel disease treatment related agents
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥Summary Statistics
↥-FinRegistry-
This endpoint is excluded from FinRegistry analyses (omitted endpoint).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1232 | 700 | 532 |
| Unadjusted period prevalence (%) | 0.24 | 0.24 | 0.23 |
| Median age at first event (years) | 40.76 | 39.02 | 43.05 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 987
- Matched controls
- 9869
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
A07EC02
ATC
mesalazine; oral, rectal
683.8
323.0
665
30
L01BB02
ATC
mercaptopurine; oral
+∞
323.0
987
*
UJF30
NOMESCO Finland
Ileoscopy through colon
33.1
323.0
490
285
208
Kela drug reimbursment
Ulcerative colitis and Crohn's disease
2671.7
323.0
762
13
L04AX01
ATC
azathioprine; systemic
748.3
323.0
572
18
A07EA06
ATC
budesonide; oral, local oral
519.3
323.0
521
21
H02AB06
ATC
prednisolone; systemic
27.3
323.0
852
1852
K51.9
ICD-10 Finland
Ulcerative colitis, unspecified
238.1
323.0
381
26
K51.5
ICD-10 Finland
Left sided colitis
1082.3
323.0
466
8
UJF32
NOMESCO Finland
Coloscopy
16.6
318.4
623
920
K51.3
ICD-10 Finland
Ulcerative (chronic) rectosigmoiditis
+∞
298.5
271
*
A07EA02
ATC
hydrocortisone; rectal
623.7
290.4
274
6
K50.8
ICD-10 Finland
Other Crohn disease
359.3
229.0
223
8
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
9.5
194.2
487
920
K50.0
ICD-10 Finland
Crohn disease of small intestine
217.6
191.7
193
11
K50.1
ICD-10 Finland
Crohn disease of large intestine
313.9
182.4
180
7
K50.9
ICD-10 Finland
Crohn disease, unspecified
185.5
178.4
182
12
326
Kela drug reimbursment
Adalimumab, golimumab, infliximab and ustekinumab (intestinal diseases)
2081.7
177.6
167
*
K51.8
ICD-10 Finland
Other ulcerative colitis
887.6
158.1
151
*
H02AB07
ATC
prednisone; oral
11.9
155.3
312
369
K51.1
ICD-10 Finland
Ulcerative (chronic) ileocolitis
1713.3
153.3
145
*
K51.2
ICD-10 Finland
Ulcerative (chronic) proctitis
571.2
152.0
147
*
A07EC01
ATC
sulfasalazine; oral, rectal
36.5
133.8
173
57
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
19.6
131.0
205
130
C91.0
ICD-10 Finland
Acute lymphoblastic leukaemia [ALL]
225.1
117.4
119
6
ZX120
NOMESCO Finland
Intravenous
10.9
116.1
239
281
K51
ICD-10 Finland
Ulcerative colitis
558.9
103.6
101
*
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
19.3
102.3
160
98
L04AB04
ATC
adalimumab; parenteral
101.0
99.3
108
12
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
4.7
90.1
387
1195
GD1AA
NOMESCO Finland
Thorax X-ray examination
4.1
88.2
485
1885
H02AB09
ATC
hydrocortisone; systemic
22.1
83.0
123
63
K51.0
ICD-10 Finland
Ulcerative (chronic) pancolitis
+∞
79.2
75
*
9835/3-C42.1
ICD-O-3
Precursor cell lymphoblastic leukemia, NOS, of bone marrow
217.3
78.5
80
*
L01BA01
ATC
methotrexate; systemic (folic acid analog.)
155.1
68.9
72
5
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
11.5
66.1
128
126
JF1CG
NOMESCO Finland
Extensive MRI of small bowel
87.6
66.0
73
9
J01MA02
ATC
ciprofloxacin; systemic
3.4
65.4
435
1848
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
7.5
64.7
163
253
A02BC02
ATC
pantoprazole; systemic
3.2
64.4
662
3833
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
6.5
61.9
175
318
O99.6
ICD-10 Finland
Diseases of the digestive system complicating pregnancy, childbirth and the puerperium
52.4
61.2
73
15
D94
ICPC
Chronic enteritis/ulcerative colitis
327.3
61.1
61
*
UJF92
NOMESCO Finland
Capsular endoscopy
20.0
61.0
93
51
TPH04
NOMESCO Finland
Cathetrisation of vein
4.0
60.7
286
905
WX002
NOMESCO Finland
Sedation and analgesia
4.2
60.2
266
793
P01AB01
ATC
metronidazole; oral, rectal
3.0
56.5
482
2372
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
11.3
54.1
105
103
XW000
NOMESCO Finland
Bone marrow biopsy
12.0
53.1
100
92
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
19.5
49.7
76
42
4AA12
NOMESCO Finland
NA
+∞
49.4
47
*
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
15.5
47.4
79
55
UJF14
NOMESCO Finland
Enteroscopy of ileoanal anastomosis
479.4
46.7
46
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
4.0
46.5
208
612
JF1DG
NOMESCO Finland
Small bowel very extensive MRI with with high intensity magnet
246.4
46.4
47
*
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
8.2
44.7
104
140
TAB00
NOMESCO Finland
Lumbar puncture
7.0
42.1
109
172
4AB02
NOMESCO Finland
NA
+∞
42.0
40
*
L04AC05
ATC
ustekinumab; parenteral
219.1
41.2
42
*
K73.2
ICD-10 Finland
Chronic active hepatitis, not elsewhere classified
413.7
40.4
40
*
A05AA02
ATC
ursodeoxycholic acid; oral
18.5
39.3
61
35
Z85.6
ICD-10 Finland
Personal history of leukaemia
208.2
39.1
40
*
L04AD01
ATC
ciclosporin; systemic
17.4
37.2
59
36
K50
ICD-10 Finland
Crohn disease [regional enteritis]
197.4
37.0
38
*
A07EA01
ATC
prednisolone; rectal
128.0
34.9
37
*
C92.0
ICD-10 Finland
Acute myeloblastic leukaemia [AML]
52.0
33.7
40
8
M07.5*K51.9
ICD-10 Finland
Arthropathy in ulcerative colitis
+∞
32.5
31
*
L04AB06
ATC
golimumab; parenteral
88.0
30.9
34
*
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
9.8
30.8
63
68
R50.9
ICD-10 Finland
Fever, unspecified
3.1
30.5
192
719
3005
Kela drug reimbursment
Tofacitinib
+∞
30.4
29
*
K75.4
ICD-10 Finland
Autoimmune hepatitis
311.5
30.0
30
*
WVA20
NOMESCO Finland
Medicine administration
13.4
29.1
51
40
JF1BD
NOMESCO Finland
Very extensive small bowel CT
68.1
29.1
33
5
JN3BD
NOMESCO Finland
Extensive abdominal CT
3.7
28.8
135
403
NEA10
NOMESCO Finland
Exploration of soft tissue of pelvis, percutaneous
50.2
28.6
34
7
K52.88
ICD-10 Finland
Other specified noninfective gastroenteritis and colitis
12.8
28.0
50
41
ZX131
NOMESCO Finland
Intrathecal
289.3
27.9
28
*
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
6.6
27.2
72
117
M07.4*K50.9
ICD-10 Finland
Arthropathy in Crohn's disease [regional enteritis]
278.3
26.8
27
*
A06AC01
ATC
ispaghula (psylla seeds); oral
2.6
26.6
223
991
WW500
NOMESCO Finland
Blood transfusion
6.7
26.6
69
109
H02AB04
ATC
methylprednisolone; systemic
3.4
26.5
142
471
L04AA29
ATC
tofacitinib; oral
+∞
26.2
25
*
C10AC01
ATC
colestyramine; oral
10.1
26.0
52
54
J05AB11
ATC
valaciclovir; oral
3.1
25.9
156
563
A07EC03
ATC
olsalazine; oral
+∞
25.1
24
*
253
Kela drug reimbursment
NA
+∞
24.1
23
*
3042
Kela drug reimbursment
NA
+∞
24.1
23
*
9811/3-C42.1
ICD-O-3
B lymphoblastic leukemia/lymphoma, NOS, of bone marrow
245.7
23.7
24
*
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.1
23.4
379
2287
C91.1
ICD-10 Finland
Chronic lymphocytic leukaemia of B-cell type
25.4
23.2
32
13
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
4.5
22.9
84
200
H02AB02
ATC
dexamethasone; systemic
3.4
22.6
116
371
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
8.1
22.5
51
66
J01MA12
ATC
levofloxacin; systemic
2.8
22.3
161
649
WX302
NOMESCO Finland
Thoracal epidural anesthesy
5.0
22.2
73
155
C92.4
ICD-10 Finland
Acute promyelocytic leukaemia [PML]
+∞
22.0
21
*
3AC01
NOMESCO Finland
NA
17.6
21.9
34
20
K83.0
ICD-10 Finland
Cholangitis
18.9
21.8
33
18
WX408
NOMESCO Finland
General anesthesy, balanced
2.2
21.7
268
1430
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
4.4
21.2
79
191
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
9.2
21.0
44
50
N02AX02
ATC
tramadol; systemic, rectal
2.0
20.5
351
2137
WW200
NOMESCO Finland
Immunization
5.9
19.9
56
99
JFH30
NOMESCO Finland
Total colectomy, mucosal proctectomy and ileoanal anastomosis without ileostomy
+∞
19.9
19
*
1XX02
NOMESCO Finland
NA
+∞
19.9
19
*
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.3
19.8
218
1097
Z2221
NOMESCO Finland
Medical doctor
2.0
19.1
290
1674
C95.0
ICD-10 Finland
Acute leukaemia of unspecified cell type
56.2
19.0
22
*
K76.9
ICD-10 Finland
Liver disease, unspecified
13.7
18.8
32
24
5561A
ICD-9 Finland
Idiopathic proctocolitis, Ulcerative (chronic) ileocolitis
+∞
18.8
18
*
N02BE01
ATC
paracetamol; systemic, rectal
2.0
18.7
780
6442
JFG00
NOMESCO Finland
Closure of loop enterostomy without resection
39.2
18.6
23
6
D64.9
ICD-10 Finland
Anaemia, unspecified
3.7
18.5
82
233
A04AA01
ATC
ondansetron; systemic, rectal
3.8
18.1
80
226
A41.9
ICD-10 Finland
Sepsis, unspecified
6.1
17.9
49
84
JKE98
NOMESCO Finland
Other transduodenal endoscopic operation on bile duct or ampulla of Vater
14.0
17.8
30
22
C05AA08
ATC
fluocortolone; rectal, topical
2.6
17.8
138
574
TPX10
NOMESCO Finland
Implantation of vascular injection port
6.2
17.7
48
81
C91.9
ICD-10 Finland
Lymphoid leukaemia, unspecified
183.1
17.6
18
*
ZXE00
NOMESCO Finland
One hour or less
1.8
17.2
386
2556
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
4.6
16.9
59
134
4AA33
NOMESCO Finland
NA
+∞
16.7
16
*
ZX114
NOMESCO Finland
Intramuscular
8.1
16.7
37
47
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
6.1
15.9
43
73
ZX121
NOMESCO Finland
Central venous catheter
26.8
15.6
21
8
M05BA04
ATC
alendronic acid; oral
4.9
15.3
50
106
L03AA02
ATC
filgrastim; parenteral
5.8
14.9
42
75
A02BC03
ATC
lansoprazole; oral
2.0
14.9
225
1280
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.7
14.8
404
2805
B03BA03
ATC
hydroxocobalamin; parenteral
4.8
14.8
49
106
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
2.4
14.7
138
636
JFH33
NOMESCO Finland
Total colectomy, mucosal proctectomy, ileoanal anastomosis and ileostomy
+∞
14.6
14
*
2040A
ICD-9 Finland
Lymphoid leukaemia, Acute
+∞
14.6
14
*
JFH11
NOMESCO Finland
Laparoscopic colectomy
+∞
14.6
14
*
JF1AD
NOMESCO Finland
Small bowel CT
27.6
14.3
19
7
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.1
14.2
190
1028
A07AA09
ATC
vancomycin; oral
14.7
14.1
23
16
A02BC05
ATC
esomeprazole; systemic
1.8
14.1
324
2125
D69.6
ICD-10 Finland
Thrombocytopenia, unspecified
9.0
14.0
29
33
XF400
NOMESCO Finland
ECG with 12 standard connections
2.3
13.7
134
627
J02AC01
ATC
fluconazole; systemic
1.7
13.6
360
2464
A02BC01
ATC
omeprazole; systemic
1.9
12.8
216
1272
K56.6
ICD-10 Finland
Other and unspecified intestinal obstruction
6.1
12.8
34
57
M45
ICD-10 Finland
Ankylosing spondylitis
10.7
12.8
24
23
N02AJ06
ATC
codeine and paracetamol; systemic
1.7
12.8
337
2290
JFA15
NOMESCO Finland
Endoscopic polypectomy in colon
4.6
12.7
44
100
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.1
12.5
157
824
JFB20
NOMESCO Finland
Ileocaecal resection
20.3
12.5
18
9
JFA98
NOMESCO Finland
Other transluminal endoscopic local operation on intestine
8.6
12.3
26
31
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.9
12.3
77
284
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.8
12.2
224
1355
R74.0
ICD-10 Finland
Elevation of levels of transaminase and lactic acid dehydrogenase [LDH]
6.5
12.2
31
49
UJF30
SPAT
NA
21.6
12.0
17
8
UJF12
NOMESCO Finland
Enteroscopy through intestinal stoma
47.3
11.9
14
*
B01AB05
ATC
enoxaparin; parenteral
1.8
11.9
218
1318
JL5BG
NOMESCO Finland
MRI examinaiton of bile and pancreas ducts with high intesity magnet
6.0
11.9
32
55
JL5SB
NOMESCO Finland
Endoscopic retrograd cholangiopancreaticography
8.5
11.8
25
30
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.6
11.6
403
2938
JFB00
NOMESCO Finland
Partial resection of small intestine
9.4
11.5
23
25
K73.0
ICD-10 Finland
Chronic persistent hepatitis, not elsewhere classified
+∞
11.5
11
*
56300
ICD-8 Finland
Chronic enteritis and ulcerative colitis, Regional enteritis
+∞
11.5
11
*
JGB50
NOMESCO Finland
Mucosal proctectomy and ileoanal anastomosis
+∞
11.5
11
*
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
2.0
11.3
146
772
J01DB01
ATC
cefalexin; oral
1.7
11.3
769
6657
JN3AD
NOMESCO Finland
Abdominal CT examination
2.8
11.2
71
264
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
2.8
11.2
73
275
OAB74
NOMESCO Finland
Nutritional guidance related to treatment and rehabilitation for medical condition
14.1
11.0
18
13
UJK02
NOMESCO Finland
ERCP
6.4
11.0
28
45
Z3231
NOMESCO Finland
Registered nurse
1.7
10.9
242
1549
9861/3-C42.1
ICD-O-3
Acute myeloid leukemia, NOS, of bone marrow
43.8
10.9
13
*
TGC00
NOMESCO Finland
Bronchial lavation
8.4
10.8
23
28
JJ1LE
NOMESCO Finland
Ultrasound elastography of liver
9.0
10.8
22
25
WD135
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
18.0
10.7
16
9
K03.66
ICD-10 Finland
Tooth plaque
2.6
10.7
81
332
A07DA03
ATC
loperamide; oral
4.9
10.6
34
72
A06AC51
ATC
ispaghula, combinations; systemic
3.4
10.6
51
157
K92.1
ICD-10 Finland
Melaena
3.7
10.5
45
126
J01FA09
ATC
clarithromycin; systemic
1.7
10.5
280
1888
J05AB01
ATC
aciclovir; systemic
1.8
10.5
182
1075
JFH10
NOMESCO Finland
Total colectomy and ileostomy
+∞
10.4
10
*
5562A
ICD-9 Finland
Idiopathic proctocolitis, Ulcerative (chronic) proctitis
+∞
10.4
10
*
K51.4
ICD-10 Finland
Inflammatory polyps
+∞
10.4
10
*
L01BB03
ATC
tioguanine; oral
+∞
10.4
10
*
NA6BG
NOMESCO Finland
Sacro-iliac joint MRI examination with high intensity magnet
6.9
10.4
25
37
M04AA01
ATC
allopurinol; systemic
2.7
10.4
72
281
K75.9
ICD-10 Finland
Inflammatory liver disease, unspecified
8.9
10.3
21
24
JFG20
NOMESCO Finland
Closure of enterostomy with resection of exteriorised loop
23.6
10.3
14
6
RD210
NOMESCO Finland
NA
4.5
10.0
34
77
K73.9
ICD-10 Finland
Chronic hepatitis, unspecified
20.3
9.8
14
7
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
3.7
9.8
41
113
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
3.7
9.8
41
113
ZXD05
NOMESCO Finland
Urgent procedure
1.6
9.8
283
1948
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
2.9
9.7
60
219
56310
ICD-8 Finland
Chronic enteritis and ulcerative colitis, Ulcerative colitis
55.5
9.7
11
*
Z01.8
ICD-10 Finland
Other specified special examinations
1.8
9.5
176
1059
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
4.3
9.4
34
82
M80.4
ICD-10 Finland
Drug-induced osteoporosis with pathological fracture
101.0
9.4
10
*
JFH20
NOMESCO Finland
Proctocolectomy and ileostomy
101.0
9.4
10
*
ZX112
NOMESCO Finland
Subcutaneous
6.3
9.4
24
39
Z93.2
ICD-10 Finland
Ileostomy status
30.3
9.4
12
*
JN1DG
NOMESCO Finland
Very extensive MRI examination of upper part of abdomen with high intensity magnet
5.7
9.4
26
47
2AX04
NOMESCO Finland
NA
+∞
9.4
9
*
5552A
ICD-9 Finland
Regional enteritis, Small intestine with large intestine
+∞
9.4
9
*
L04AA33
ATC
vedolizumab; parenteral
+∞
9.4
9
*
L03AA10
ATC
lenograstim; parenteral
+∞
9.4
9
*
A01AB09
ATC
miconazole; local oral
2.5
9.3
75
319
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.6
9.3
266
1820
WX402
NOMESCO Finland
General anaesthesia
1.8
9.1
153
893
D06BX01
ATC
metronidazole; topical
2.2
9.1
92
439
WZC30
NOMESCO Finland
Teaching
2.1
9.1
103
516
601
Kela drug reimbursment
Severe malabsorption of nutrients, mainly fats
10.2
9.0
17
17
K60.3
ICD-10 Finland
Anal fistula
4.9
9.0
28
58
M13.9
ICD-10 Finland
Arthritis, unspecified
2.9
9.0
54
195
B02.9
ICD-10 Finland
Zoster without complication
3.1
8.9
46
151
B81
ICPC
Anaemia vit B12/folate deficiency
4.6
8.8
29
64
Z94.8
ICD-10 Finland
Other transplanted organ and tissue status
10.8
8.8
16
15
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
4.8
8.8
28
60
K62.5
ICD-10 Finland
Haemorrhage of anus and rectum
3.1
8.8
47
158
K56.5
ICD-10 Finland
Intestinal adhesions [bands] with obstruction
6.5
8.5
21
33
B01AB10
ATC
tinzaparin; parenteral
2.7
8.5
55
209
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
5.7
8.5
23
41
5568X
ICD-9 Finland
Idiopathic proctocolitis, Other ulcerative colitis
90.8
8.4
9
*
M87.1
ICD-10 Finland
Osteonecrosis due to drugs
90.8
8.4
9
*
M81.4
ICD-10 Finland
Drug-induced osteoporosis
90.8
8.4
9
*
ZXE10
NOMESCO Finland
More than one and less than three hours
1.6
8.4
283
2011
M07.5
ICD-10 Finland
Arthropathy in ulcerative colitis
+∞
8.3
8
*
5550A
ICD-9 Finland
Regional enteritis, Small intestine
+∞
8.3
8
*
M07.4
ICD-10 Finland
Arthropathy in Crohn disease [regional enteritis]
+∞
8.3
8
*
M25.5
ICD-10 Finland
Pain in joint
1.6
8.3
230
1557
J01FA10
ATC
azithromycin; systemic
1.5
8.2
563
4676
JX1LA
NOMESCO Finland
Kinetic X-ray of alimentary tract with pictures
33.6
8.1
10
*
L52
ICD-10 Finland
Erythema nodosum
11.8
8.1
14
12
UJF34
NOMESCO Finland
Left colonoscopy
11.8
8.1
14
12
JL5AG
NOMESCO Finland
Simple MRI examinaiton of bile and pancreas ducts with high intesity magnet
10.1
8.0
15
15
TDM10
NOMESCO Finland
Puncture of maxillary antrum
3.2
8.0
40
128
XX6XT
NOMESCO Finland
Other intravascular therapy with radiological guidance
22.2
8.0
11
5
WX110
NOMESCO Finland
Local anesthesy
1.5
8.0
662
5695
A02BA02
ATC
ranitidine; systemic
1.9
7.9
120
675
WB123
NOMESCO Finland
Demanding adjuvant cytostatic therapy
6.2
7.9
20
33
L04AA01
ATC
[U] ciclosporin; systemic
8.5
7.8
16
19
JH1CG
NOMESCO Finland
Extensive MRI of perianal area
10.9
7.8
14
13
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
2.3
7.8
69
310
K76.0
ICD-10 Finland
Fatty (change of) liver, not elsewhere classified
3.7
7.8
32
88
ZXD10
NOMESCO Finland
Scheduled procedure
1.5
7.7
304
2233
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
2.2
7.7
76
360
JFA58
NOMESCO Finland
Endoscopic dilatation of colon
18.5
7.6
11
6
TJJ00
NOMESCO Finland
Percutaneous needle biopsy of liver
18.5
7.6
11
6
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
3.4
7.6
34
101
ZX108
NOMESCO Finland
Inhalation
10.1
7.5
14
14
D11
ICPC
Diarrhoea
1.9
7.5
117
664
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.4
7.4
472
3824
Z92.6
ICD-10 Finland
Personal history of chemotherapy for neoplastic disease
80.7
7.4
8
*
JF1DM
NOMESCO Finland
Very extensive MRI of small bowel (more than 1.5 T)
80.7
7.4
8
*
1370
FHL
Colonoscopy, whole colon
13.5
7.4
12
9
R01AD08
ATC
fluticasone; nasal
1.6
7.3
245
1729
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.9
7.3
99
535
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
4.1
7.3
27
68
E0000UV
ATC
NA
1.5
7.3
343
2612
5551A
ICD-9 Finland
Regional enteritis, Large intestine
+∞
7.3
7
*
B73
ICPC
Leukaemia
+∞
7.3
7
*
Z01.2
ICD-10 Finland
Dental examination
1.5
7.3
403
3170
UJG02
NOMESCO Finland
Proctoscopy
5.2
7.3
21
41
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.5
7.2
322
2424
M46.9
ICD-10 Finland
Inflammatory spondylopathy, unspecified
15.9
7.2
11
7
JFF10
NOMESCO Finland
Loop enterostomy
15.9
7.2
11
7
J01MA14
ATC
moxifloxacin; systemic
2.4
7.2
60
262
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
3.0
7.2
39
133
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.5
7.2
267
1927
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.3
7.2
62
274
602
Kela drug reimbursment
Children's severe malnutrition
7.4
7.2
16
22
FM2CE
NOMESCO Finland
NA
4.9
7.2
22
46
D89.89
ICD-10 Finland
Other specified disorders involving the immune mechanism, not elsewhere classified
30.2
7.2
9
*
H26.3
ICD-10 Finland
Drug-induced cataract
20.2
7.1
10
5
C92.1
ICD-10 Finland
Chronic myeloid leukaemia [CML], BCR/ABL-positive
20.2
7.1
10
5
JAH00
NOMESCO Finland
Laparotomy
4.2
7.1
25
60
L88
ICPC
Rheumatoid/seropositive arthritis
6.6
7.1
17
26
JF1AB
NOMESCO Finland
Passage examination of small bowell with X-ray
6.4
7.0
17
27
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
2.5
6.9
51
208
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
2.5
6.9
54
227
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
8.3
6.8
14
17
TPW99
NOMESCO Finland
Other minor surgical procedure on peripheral vessel or lymphatic system
6.8
6.8
16
24
K62.8
ICD-10 Finland
Other specified diseases of anus and rectum
11.0
6.8
12
11
1CX01
NOMESCO Finland
NA
40.3
6.8
8
*
Z3226
NOMESCO Finland
Physiotherapist
1.7
6.7
145
910
G62.0
ICD-10 Finland
Drug-induced polyneuropathy
22.7
6.7
9
*
JN4BD
NOMESCO Finland
Extensive body CT
2.2
6.6
66
314
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
2.1
6.6
75
377
M05BA07
ATC
risedronic acid; oral
7.9
6.6
14
18
K59.1
ICD-10 Finland
Functional diarrhoea
2.6
6.6
46
182
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
2.7
6.6
42
157
WX004
NOMESCO Finland
Patient-controlled sedation
8.8
6.6
13
15
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.6
6.6
200
1376
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
3.0
6.5
35
120
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
1.9
6.5
92
504
Z2446
NOMESCO Finland
Social worker
2.1
6.5
72
360
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
2.0
6.5
86
459
R19.8
ICD-10 Finland
Other specified symptoms and signs involving the digestive system and abdomen
5.7
6.5
17
30
2AA01
NOMESCO Finland
NA
70.3
6.4
7
*
C95.9
ICD-10 Finland
Leukaemia, unspecified
70.3
6.4
7
*
J45.9
ICD-10 Finland
Asthma, unspecified
1.8
6.4
111
653
A01AB04
ATC
amphotericin B; local oral
3.2
6.4
31
99
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.7
6.4
145
926
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
2.5
6.4
48
199
NH3EA
NOMESCO Finland
Feet X-ray examination with load
6.6
6.3
15
23
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
8.2
6.3
13
16
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.5
6.3
288
2164
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
2.4
6.3
52
228
JF1CM
NOMESCO Finland
Small bowel extensive MRI with with high intensity magnet
+∞
6.3
6
*
4AC05
NOMESCO Finland
NA
+∞
6.3
6
*
5559X
ICD-9 Finland
Regional enteritis, Unspecified site
+∞
6.3
6
*
2301
FHL
Lumbar puncture in anesthesia or operating room
+∞
6.3
6
*
M09.2*K51.9
ICD-10 Finland
Juvenile arthritis in ulcerative colitis
+∞
6.3
6
*
9866/3-C42.1
ICD-O-3
Acute promyelocytic leukemia, t(15;17)(q22;q11-12) of bone marrow
+∞
6.3
6
*
DMB20
NOMESCO Finland
Functional endoscopic opening of maxillary antrum
2.6
6.2
44
176
XG410
NOMESCO Finland
Flow-volume spirometry
3.4
6.2
28
85
Z01.9
ICD-10 Finland
Special examination, unspecified
2.6
6.2
41
160
UGC12
NOMESCO Finland
Flexible bronchoscopy
2.7
6.2
40
153
L73.8
ICD-10 Finland
Other specified follicular disorders
5.8
6.2
16
28
A03FA01
ATC
metoclopramide; systemic, rectal
1.7
6.1
141
901
JL5CG
NOMESCO Finland
Extensive MRI examinaiton of bile and pancreas ducts with high intesity magnet
7.7
6.1
13
17
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.7
6.1
122
750
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.7
6.1
115
693
C90.0
ICD-10 Finland
Multiple myeloma
12.6
6.1
10
8
N02AA05
ATC
oxycodone; systemic
2.0
6.1
73
376
R11
ICD-10 Finland
Nausea and vomiting
2.0
6.0
71
364
UJH02
NOMESCO Finland
Anoscopy
2.7
6.0
39
148
D70.89
ICD-10 Finland
Neutropenic splenomegaly
5.2
6.0
17
33
Mortality – FinRegistry
↥This endpoint is excluded from FinRegistry analyses (omitted endpoint).
Relationships between endpoints
↥Index endpoint: RX_L01BB02 – 6-mercaptopurine
GWS hits: -
This endpoint is excluded from FinRegistry analyses (omitted endpoint).