This is a non-core endpoint: only basic statistics are computed.
See these related core endpoints for full statistics:
Use of donepezil
ADMED_ACHEI_DONEPEZIL
No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
1 out of 7 registries used, show all original rules. |
7943 |
4. Check minimum number of events
Min. number of events
3
|
7943 |
5. Include endpointsNone |
7943 |
6. Filter based on genotype QC (FinnGen only) |
7943 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- First used in FinnGen datafreeze
- DF2
Similar endpoints
↥List of similar endpoints to
Use of donepezil
based on the number of shared cases.
Similar with more cases:
- Use of anticholinesterases
- N06DA Anticholinesterases
- Unspecific neurodegenerative disorder
- Dementia
- Dementia, including avohilmo
Similar with less cases:
None
Case counts by codes
↥Summary Statistics
↥-FinRegistry-
This endpoint is excluded from FinRegistry analyses (omitted endpoint).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 7943 | 3882 | 4061 |
| Unadjusted period prevalence (%) | 1.56 | 1.32 | 1.79 |
| Median age at first event (years) | 78.24 | 78.42 | 78.07 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 6584
- Matched controls
- 63637
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
SPAT1053
SPAT
Memory test
4.3
323.0
2952
10082
N06DA02
ATC
donepezil; oral
+∞
323.0
6584
971
P70
ICPC
Dementia
9.1
323.0
828
985
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
4.6
323.0
1608
4191
G30.8
ICD-10 Finland
Other Alzheimer disease
8.2
323.0
821
1084
P20
ICPC
Memory disturbance
6.8
323.0
3218
7859
G30
ICD-10 Finland
Alzheimer disease
16.4
323.0
593
381
N05AX08
ATC
risperidone; systemic
5.8
323.0
1645
3459
G30.9
ICD-10 Finland
Alzheimer disease, unspecified
13.8
323.0
1854
1758
307
Kela drug reimbursment
Tacrine, donepezil, rivastigmine, galantamine and other major and expensive drugs used to treat Alzheimer's disease
16.2
323.0
2667
2570
N06DX01
ATC
memantine; oral
20.3
323.0
3637
3648
F00.10
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, senile onset without additional symptoms
15.6
323.0
775
540
F00.10*G30.1
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, senile onset without additional symptoms
15.7
323.0
1671
1345
G30.1
ICD-10 Finland
Alzheimer disease with late onset
22.0
323.0
3541
3200
F03
ICD-10 Finland
Unspecified dementia
4.8
323.0
1240
2933
G30.0
ICD-10 Finland
Alzheimer disease with early onset
20.6
320.0
493
249
N06DA03
ATC
rivastigmine; oral, transdermal
4.8
282.6
1046
2391
N05AH04
ATC
quetiapine; oral
3.6
255.2
1362
4327
SPAT1245
SPAT
Provision of support and information to patient’s family members
4.3
230.0
960
2442
A28
ICPC
Limited function/disability NOS
2.4
197.0
2176
10761
SPAT1216
SPAT
Assessment of functional ability
2.5
187.9
1920
9066
F00.20*G30.8
ICD-10 Finland
Dementia in Alzheimer's disease, atypical or mixed type without additional symptoms
6.1
186.7
545
925
F00.00*G30.0
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, presenile onset without additional symptoms
17.9
185.4
299
169
F0019, G301
ICD-10 Finland
NA
11.1
175.9
348
317
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
2.7
151.7
1248
5132
SPAT1137
SPAT
Taking care of patient’s/customer’s hygiene
2.9
146.0
1045
3940
SPAT1234
SPAT
Support of social functional capacity
3.3
144.6
823
2651
SPAT1222
SPAT
Counselling/guidance promoting independent living
2.3
142.2
1717
8595
F06.7
ICD-10 Finland
Mild cognitive disorder
4.5
142.0
539
1223
R41.3
ICD-10 Finland
Other amnesia
4.5
136.1
524
1204
F00.9
ICD-10 Finland
Dementia in Alzheimer disease, unspecified
12.0
135.4
257
214
TAB00
NOMESCO Finland
Lumbar puncture
5.6
121.8
378
685
F00.20
ICD-10 Finland
Dementia in Alzheimer's disease, atypical or mixed type without additional symptoms
7.5
115.1
286
384
SPAT1254
SPAT
Administration of medicine
2.1
109.0
1506
7858
WYA20
NOMESCO Finland
Home visit
5.2
105.7
349
678
N02BE01
ATC
paracetamol; systemic, rectal
1.9
92.6
5451
45444
R53
ICD-10 Finland
Malaise and fatigue
1.9
91.7
1801
10642
F009, G309
ICD-10 Finland
NA
9.8
91.2
191
193
N06AX11
ATC
mirtazapine; oral
1.8
86.8
2040
12758
F00.00
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, presenile onset without additional symptoms
21.1
86.8
131
61
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.7
82.6
2523
17029
N05BA04
ATC
oxazepam; oral
1.8
77.3
1737
10624
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
2.5
70.1
586
2357
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.7
69.1
1679
10453
L28
ICPC
Limited function/disability (L)
1.8
66.5
1535
9389
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.8
66.4
1374
8117
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
1.9
65.9
1040
5583
AA1AD
NOMESCO Finland
CT of head and brain
1.6
63.4
1975
13145
SPAT1301
SPAT
No procedures
1.6
62.5
2290
15892
F001, G301
ICD-10 Finland
NA
16.6
61.2
100
59
F0009, G300
ICD-10 Finland
NA
11.9
57.4
108
89
N06AB10
ATC
escitalopram; oral
2.0
56.6
858
4517
N07AA05
ATC
NA
42.7
55.8
70
16
XA800
NOMESCO Finland
Neuropsychological investigation
4.2
55.4
224
535
130
Kela drug reimbursment
Malignant tumour
0.3
53.4
133
3915
SPAT1304
SPAT
Counselling and guidance related to ageing
1.9
52.6
846
4542
SPAT1252
SPAT
Overall medication plan or its review
2.1
50.9
673
3346
SPAT1101
SPAT
Orthostatic test
2.2
49.1
544
2504
SPAT1360
SPAT
Extensive global examination
2.1
49.0
637
3145
A04
ICPC
Weakness/tiredness general
1.7
46.4
1051
6303
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.6
46.2
1368
8844
F05.1
ICD-10 Finland
Delirium superimposed on dementia
5.2
46.1
148
279
F00
ICD-10 Finland
Dementia in Alzheimer disease
9.1
45.1
97
104
SPAT1172
SPAT
Guidance concerning hydration
2.7
44.6
333
1251
N03AG01
ATC
valproic acid; systemic, rectal
2.6
44.4
349
1349
F00.1
ICD-10 Finland
Dementia in Alzheimer disease with late onset
12.7
43.0
78
60
N06AX26
ATC
vortioxetine; oral
3.0
43.0
263
871
H02AB02
ATC
dexamethasone; systemic
0.3
41.7
118
3285
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
2.1
41.5
533
2611
N05AH03
ATC
olanzapine; systemic
2.9
41.0
269
935
SPAT1246
SPAT
Screening of depression or other psychiatric problem
3.4
40.0
205
599
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
2.2
40.0
424
1909
SPAT1139
SPAT
Nutrition survey
2.6
38.9
300
1148
U04
ICPC
Incontinence urine
2.1
36.0
442
2124
R41.0
ICD-10 Finland
Disorientation, unspecified
2.2
35.3
372
1668
A29
ICPC
General symptom/complaint other
1.7
35.3
819
4916
A06AD11
ATC
lactulose; oral
1.5
35.2
1435
9928
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.4
35.2
2152
16167
F00.14
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, senile onset other additional symptoms of mixed type
10.4
34.1
68
64
R41
ICD-10 Finland
Other symptoms and signs involving cognitive functions and awareness
4.9
33.0
112
226
F21
ICPC
NA
3.5
32.1
153
424
R55
ICD-10 Finland
Syncope and collapse
1.6
32.1
922
5855
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.4
31.9
1968
14743
G91.2
ICD-10 Finland
Normal-pressure hydrocephalus
3.1
31.6
184
592
SPAT1229
SPAT
Assessment of need for aid
1.7
30.9
723
4338
F00.19
ICD-10 Finland
Dementia in Alzheimer's disease with late onset without information about additional symptoms
11.5
30.8
58
49
Z02.4
ICD-10 Finland
Examination for driving licence
0.7
30.6
889
12197
A98
ICPC
Health maint/preventive medicine
1.4
30.4
4968
43676
N05BA06
ATC
lorazepam; systemic, sublingual
2.0
30.2
411
2055
A03FA01
ATC
metoclopramide; systemic, rectal
0.6
29.7
568
8507
N06DA04
ATC
galantamine; oral
2.3
29.7
295
1287
SAD01
NOMESCO Finland
Assessment of need for oral health care, standard
1.9
29.2
489
2641
SPAT1263
SPAT
Sampling
1.4
29.0
2467
19452
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
2.0
28.8
375
1843
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.5
28.4
1104
7511
F0014, G301
ICD-10 Finland
NA
9.1
28.3
60
64
SPAT1305
SPAT
Counselling and guidance related to physical exercise
1.7
27.8
663
3993
S06.0
ICD-10 Finland
Concussion
1.7
27.5
632
3764
S01.0
ICD-10 Finland
Open wound of scalp
1.8
27.5
542
3086
SPAT1292
SPAT
Other function in accordance with SHToL (Finnish classification of nursing interventions)
1.7
27.4
678
4126
N06AB04
ATC
citalopram; systemic
1.5
26.9
1185
8267
S72.0
ICD-10 Finland
Fracture of neck of femur
1.8
26.6
480
2654
N02AA05
ATC
oxycodone; systemic
1.5
25.5
1179
8300
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.4
25.3
1877
14385
SPAT1050
SPAT
Extensive neurological examination
2.6
25.3
194
742
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
1.5
25.2
1011
6909
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
0.6
25.1
414
6435
C10AA01
ATC
simvastatin; oral
1.3
24.8
3443
28969
J01DB01
ATC
cefalexin; oral
1.3
24.7
4403
38390
N28
ICPC
Limited function/disability (N)
3.0
24.6
144
467
SPAT1251
SPAT
Organisation of medication
1.9
23.9
356
1841
SPAT1100
SPAT
Long-term monitoring of blood pressure
1.6
23.7
612
3762
NFB20
NOMESCO Finland
Primary partial prosthetic replacement of hip joint using cement, other or unspecified
2.0
23.5
316
1574
W19
ICD-10 Finland
Unspecified fall
1.6
22.3
634
3991
N06AB06
ATC
sertraline; oral
1.8
21.8
391
2158
R06.0
ICD-10 Finland
Dyspnoea
0.7
21.4
1034
13104
Z75.5
ICD-10 Finland
Holiday relief care
2.8
21.1
141
498
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
0.2
21.0
28
1137
F0029, G308
ICD-10 Finland
NA
6.1
20.5
56
89
G04BD12
ATC
mirabegron; oral
1.5
20.4
717
4745
AXX01
SPAT
NA
2.8
20.3
133
466
UGC12
NOMESCO Finland
Flexible bronchoscopy
0.5
19.6
217
3739
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
0.7
19.6
787
10294
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
0.6
19.6
318
4972
N02AJ06
ATC
codeine and paracetamol; systemic
0.7
19.4
989
12459
F01.20
ICD-10 Finland
Subcortical vascular dementia without additional symptoms
3.3
18.8
96
285
AA5DR
NOMESCO Finland
Brain metabolism PET with CT
19.4
18.7
28
14
J01CA08
ATC
pivmecillinam; oral
1.3
18.6
2174
17623
WX402
NOMESCO Finland
General anaesthesia
0.6
18.5
239
3958
SPAT1167
SPAT
Insertion of urinary catheter
1.8
18.4
319
1739
Z02.7
ICD-10 Finland
Issue of medical certificate
1.7
18.3
370
2120
AAF05
NOMESCO Finland
Ventriculoperitoneal shunt
2.8
18.1
121
430
N02AX02
ATC
tramadol; systemic, rectal
0.8
18.0
1771
20460
SPAT1226
SPAT
Implementation of occupational therapy rehabilitation plan
2.0
17.9
232
1139
SPAT1279
SPAT
Preparation of immediate hospitalisation
2.5
17.7
136
522
A04AA01
ATC
ondansetron; systemic, rectal
0.4
17.4
87
1927
SPAT1014
SPAT
Treatment of eyes
2.3
17.3
164
703
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
0.7
17.3
734
9534
F00.09
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, presenile onset information on additional symptoms is lacking
23.3
17.0
24
10
Z13.3
ICD-10 Finland
Special screening examination for mental and behavioural disorders
11.1
16.6
31
27
N06AX16
ATC
venlafaxine; oral
1.7
16.5
390
2337
WF049
NOMESCO Finland
Radiotherapy of metastasis
0.3
16.5
31
1046
N29
ICPC
Neurological sympt/complt other
2.5
16.5
133
528
N05AD01
ATC
haloperidol; systemic
1.9
16.4
249
1299
ZX120
NOMESCO Finland
Intravenous
0.6
16.4
212
3509
B03BA03
ATC
hydroxocobalamin; parenteral
1.5
16.3
511
3289
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.4
16.2
1060
7875
R42
ICD-10 Finland
Dizziness and giddiness
1.3
16.2
1521
11928
G31.0
ICD-10 Finland
Circumscribed brain atrophy
4.4
16.1
58
128
N27
ICPC
Fear of neurological disease other
2.7
15.9
107
383
SPAT1221
SPAT
Guidance concerning rehabilitation services and livelihood
2.7
15.8
111
407
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
0.7
15.8
685
8877
I95.1
ICD-10 Finland
Orthostatic hypotension
1.7
15.7
339
1980
E86
ICD-10 Finland
Volume depletion
1.9
15.7
228
1173
C34.1
ICD-10 Finland
Malignant neoplasm: Upper lobe, bronchus or lung
0.2
15.7
16
755
I48.0
ICD-10 Finland
Paroxysmal atrial fibrillation
0.5
15.0
118
2241
C03DA01
ATC
spironolactone; oral
0.7
14.9
464
6363
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
1.6
14.9
447
2851
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
0.8
14.7
1068
12874
R23.8
ICD-10 Finland
Other and unspecified skin changes
0.7
14.6
440
6073
L82
ICD-10 Finland
Seborrhoeic keratosis
0.7
14.6
434
6000
SPAT1125
SPAT
Stoma care and guidance
2.1
14.6
160
735
A49.9
ICD-10 Finland
Bacterial infection, unspecified
1.4
14.6
806
5817
N04BA02
ATC
levodopa and decarboxylase inhibitor; oral
1.7
14.6
321
1890
I67.3
ICD-10 Finland
Progressive vascular leukoencephalopathy
2.3
14.5
135
577
U07.1
ICD-10 Finland
Emergency use of U07.1 | COVID-19, virus identified
1.6
14.4
341
2045
T90.5
ICD-10 Finland
Sequelae of intracranial injury
3.9
14.4
59
148
A04AA02
ATC
granisetron; systemic, transdermal
0.4
14.1
71
1570
R1250
NOMESCO Finland
Evaluation of functional capability
2.5
14.0
108
420
G31.8
ICD-10 Finland
Other specified degenerative diseases of nervous system
3.6
13.9
63
172
H02AB06
ATC
prednisolone; systemic
0.8
13.9
2051
22835
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
0.3
13.9
37
1057
L01BC06
ATC
capecitabine; oral
0.3
13.8
36
1038
R03AC02
ATC
salbutamol; inhalant
0.8
13.7
1925
21552
J01EA01
ATC
trimethoprim; systemic
1.3
13.7
1653
13344
G40.9
ICD-10 Finland
Epilepsy, unspecified
1.9
13.6
199
1027
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
0.3
13.4
39
1070
F0011, G301
ICD-10 Finland
NA
8.0
13.1
29
35
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.3
13.0
964
7284
A69
ICPC
General and Unspecified, Other reason for encounter NEC
1.9
12.9
196
1026
Z01.9
ICD-10 Finland
Special examination, unspecified
1.7
12.8
277
1621
S70.0
ICD-10 Finland
Contusion of hip
1.7
12.7
282
1664
4912B
ICD-9 Finland
Chronic bronchitis, Obstructive chronic bronchitis[BRONCHITIS OBSTRUCTIVA CUM EMPHYSEMATE]
0.1
12.6
6
464
R03AK03
ATC
[D] fenoterol & other drugs for obstructive airway dis; inhalant
0.6
12.6
247
3709
WF002
NOMESCO Finland
Radical radiotherapy
0.5
12.5
82
1653
EBA15
NOMESCO Finland
Extraction of large number of teeth
1.8
12.3
193
1023
Z29
ICPC
Social problem NOS
2.2
12.1
118
516
S06.5
ICD-10 Finland
Traumatic subdural haemorrhage
1.6
12.1
278
1659
XX3DW
NOMESCO Finland
Time consuming IT work
0.6
12.0
225
3416
8070/3-C34.9
ICD-O-3
Squamous cell carcinoma, NOS, of lung, NOS
0.2
11.9
8
490
FN2BA
NOMESCO Finland
Percutaneous transluminal coronary angioplasty with stent (includes balloon pre-dilation)
0.5
11.9
121
2130
SPAT1157
SPAT
Guidance concerning treatment of mouth and mucous membranes
2.4
11.9
102
420
J69.0
ICD-10 Finland
Pneumonitis due to food and vomit
1.9
11.8
170
874
J01.0
ICD-10 Finland
Acute maxillary sinusitis
0.7
11.8
347
4812
201
Kela drug reimbursment
Chronic cardiac insufficiency
0.6
11.7
232
3479
G04BD08
ATC
solifenacin; oral
1.5
11.6
473
3220
F0012, G301
ICD-10 Finland
NA
11.3
11.5
21
18
L89
ICD-10 Finland
Decubitus ulcer and pressure area
1.9
11.4
155
782
N39.4
ICD-10 Finland
Other specified urinary incontinence
1.4
11.4
518
3604
J96.1
ICD-10 Finland
Chronic respiratory failure
0.4
11.3
44
1068
F00.13
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, senile onset other additional symptoms, mainly depression
10.7
11.2
21
19
E0000UV
ATC
NA
1.2
11.1
1905
15919
SPAT1307
SPAT
Psychosocial counselling and guidance
2.0
11.0
130
623
SPAT1284
SPAT
Extensive health certificate
2.0
11.0
138
675
L75
ICPC
Fracture: femur
2.1
10.9
125
590
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.2
10.9
2183
18520
P05
ICPC
Senility, feeling/behaving old
2.8
10.9
68
235
F00.11
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, senile onset other additional symptoms, mainly paranoidism
6.5
10.8
27
40
M04AA01
ATC
allopurinol; systemic
0.8
10.7
644
7990
-2
ICPC
NA
2.6
10.6
73
269
207
Kela drug reimbursment
Chronic arrhythmias
0.8
10.6
823
9888
N40
ICD-10 Finland
Hyperplasia of prostate
1.2
10.6
1619
13356
SPAT1215
SPAT
Assessment of need for medical rehabilitation
1.7
10.6
230
1353
SPAT1111
SPAT
Planning of analgesia
2.3
10.5
91
378
I50.1
ICD-10 Finland
Left ventricular failure
0.6
10.5
199
3012
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
1.6
10.5
278
1723
SAD02
NOMESCO Finland
Assessment of need for oral health care, extensive
2.2
10.5
107
482
D38.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Trachea, bronchus and lung
0.5
10.4
63
1301
G04CB01
ATC
finasteride; oral (testosterone-5-alpha reductase inhibitors)
1.3
10.3
928
7186
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
1.6
10.3
268
1649
WZC30
NOMESCO Finland
Teaching
0.7
10.3
298
4148
L03AA02
ATC
filgrastim; parenteral
0.3
10.2
21
675
R32
ICD-10 Finland
Unspecified urinary incontinence
1.8
10.2
186
1037
F00.04
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, presenile onset other additional symptoms of mixed type
31.5
10.1
13
*
R02
ICPC
Shortness of breath/dyspnoea
0.7
10.1
400
5280
F00.01
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, presenile onset other additional symptoms, mainly paranoidism
11.6
10.1
18
15
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
0.5
10.0
83
1551
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.2
10.0
2257
19323
KMAK
NOMESCO Finland
NA
1.2
10.0
1876
15788
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
0.7
9.9
269
3790
K03.82
ICD-10 Finland
Split tooth for reasons other than trauma
0.5
9.9
71
1384
R99
ICD-10 Finland
Other ill-defined and unspecified causes of mortality
1.9
9.9
146
759
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
1.7
9.8
187
1059
SPAT1276
SPAT
Outlining of treatment with patient or their family members
1.8
9.8
165
899
N06AX21
ATC
duloxetine; oral
1.5
9.8
384
2597
B01AB10
ATC
tinzaparin; parenteral
0.6
9.8
145
2315
4120X
ICD-9 Finland
Old myocardial infarction[STATUS POST INFARCTUM CORDIS,MÄÄRITTELEMÄT]
0.4
9.7
37
902
Z28
ICPC
Limited function/disability (Z)
3.0
9.6
53
171
WW500
NOMESCO Finland
Blood transfusion
0.5
9.6
80
1493
K08.3
ICD-10 Finland
Retained dental root
1.5
9.6
331
2179
TPH07
NOMESCO Finland
Cathetrisation of artery
0.7
9.5
337
4528
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.5
9.5
359
2411
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.3
9.5
826
6370
XF400
NOMESCO Finland
ECG with 12 standard connections
0.8
9.4
760
9098
F002, G308
ICD-10 Finland
NA
7.1
9.4
22
30
F009, F03
ICD-10 Finland
NA
7.1
9.4
22
30
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
2.1
9.4
106
500
N99
ICPC
Neurological disease other
2.4
9.3
74
296
E000001
ATC
NA
1.3
9.3
964
7600
R4110
NOMESCO Finland
Physiotherapy
0.8
9.3
961
11188
JN4BD
NOMESCO Finland
Extensive body CT
0.7
9.3
346
4606
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
2.1
9.2
101
471
A10AE04
ATC
insulin glargine; parenteral
1.4
9.2
523
3782
SPAT1058
SPAT
PEF monitoring instruction
0.6
9.2
183
2736
R10.1
ICD-10 Finland
Pain localized to upper abdomen
0.7
9.2
428
5506
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
0.6
9.2
117
1936
S01.8
ICD-10 Finland
Open wound of other parts of head
2.3
9.1
79
331
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
0.4
9.1
31
790
S28
ICPC
Limited function/disability (S)
3.1
9.1
47
146
SPAT1294
SPAT
Other function in accordance with health social work nomenclature
1.7
9.0
167
941
L57.0
ICD-10 Finland
Actinic keratosis
0.7
9.0
484
6103
SPAT1231
SPAT
Assessment of adjustments needed in living environment
1.7
9.0
177
1013
H02AB07
ATC
prednisone; oral
0.8
9.0
520
6493
NF1AA
NOMESCO Finland
Hip X-ray examination
1.3
9.0
577
4258
S01
ICD-10 Finland
Open wound of head
2.3
8.9
78
329
F01.29
ICD-10 Finland
Subcortical vascular dementia without information on additional symptoms
3.2
8.9
45
138
R03DA04
ATC
theophylline; systemic, rectal
0.7
8.8
238
3353
SPAT1281
SPAT
Other administrative function
1.4
8.8
387
2680
R03BB04
ATC
tiotropium bromide; inhalant
0.7
8.8
425
5441
A27
ICPC
Fear of other disease NOS
1.6
8.7
230
1427
AAA20
NOMESCO Finland
Insertion of intraventricular pressure monitoring device
4.0
8.7
33
80
G04CA52
ATC
tamsulosin and dutasteride; systemic
1.3
8.6
603
4510
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
1.5
8.6
264
1699
N87
ICPC
Parkinsonism
2.0
8.5
104
506
R56.8
ICD-10 Finland
Other and unspecified convulsions
1.6
8.5
220
1361
JN4AD
NOMESCO Finland
Body CT examination
0.7
8.4
192
2792
F00.2
ICD-10 Finland
Dementia in Alzheimer disease, atypical or mixed type
7.9
8.3
18
22
N95.1
ICD-10 Finland
Menopausal and female climacteric states
0.4
8.3
27
704
IHZ08
SPAT
NA
19.4
8.3
12
6
S52.5
ICD-10 Finland
Fracture of lower end of radius
1.3
8.3
501
3664
N30.0
ICD-10 Finland
Acute cystitis
1.3
8.3
834
6546
SPAT1243
SPAT
Psychiatric/psychological examination
2.8
8.2
49
168
P04
ICPC
Feeling/behaving irritable/angry
4.9
8.2
25
49
EBA00
NOMESCO Finland
Extraction of tooth
1.2
8.2
1308
10803
N05AH02
ATC
clozapine; systemic
3.7
8.1
34
90
N18
ICPC
Paralysis/weakness
1.8
8.1
123
649
-1
ICD-10 Finland
NA
2.2
8.1
82
370
SPAT1244
SPAT
Occupational therapy
2.3
8.0
71
302
M70.6
ICD-10 Finland
Trochanteric bursitis
0.7
7.9
352
4562
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.2
7.9
1549
13043
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
1.3
7.9
635
4843
8000/3-C34.9
ICD-O-3
Neoplasm, malignant of lung, NOS
0.4
7.8
23
627
S18
ICPC
Laceration/cut
0.8
7.8
1779
19313
NF1BA
NOMESCO Finland
Hip extensive X-ray examination
1.5
7.8
222
1405
R18
ICD-10 Finland
Ascites
0.3
7.8
20
576
K80
ICPC
Cardiac arrhythmia NOS
0.7
7.8
181
2620
B01AC30
ATC
platelet aggregation inhibitors excl. heparin - combinations
1.3
7.8
552
4136
F00.12
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, senile onset, other additional symptoms, mainly hallucinations
7.0
7.7
18
25
R45.5
ICD-10 Finland
Hostility
12.6
7.7
13
10
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
0.6
7.7
124
1940
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
0.5
7.7
70
1270
AAD10
NOMESCO Finland
Evacuation of chronic subdural haematoma
1.9
7.7
108
558
R74
ICPC
Upper respiratory infection acute
0.8
7.6
422
5305
K91
ICPC
Cerebrovascular disease
1.9
7.6
103
522
C79.5
ICD-10 Finland
Secondary malignant neoplasm of bone and bone marrow
0.4
7.6
24
633
G91.9
ICD-10 Finland
Hydrocephalus, unspecified
3.2
7.6
38
117
A11CC03
ATC
alfacalcidol; systemic
0.4
7.6
33
759
F06.9
ICD-10 Finland
Unspecified mental disorder due to brain damage and dysfunction and to physical disease
4.2
7.5
27
63
NFJ54
NOMESCO Finland
Internal fixation of fracture of upper femur with intramedullary nail
1.7
7.5
154
896
R03AK07
ATC
formoterol and budesonide; inhalant
0.8
7.5
445
5537
G04CA02
ATC
tamsulosin; oral
1.2
7.4
1708
14563
I21.41
ICD-10 Finland
Acute subendocardial infarction stenosed coronary artery
0.6
7.4
151
2246
F01.2
ICD-10 Finland
Subcortical vascular dementia
2.5
7.4
55
213
X59
ICD-10 Finland
Exposure to unspecified factor
1.3
7.4
776
6119
C78.7
ICD-10 Finland
Secondary malignant neoplasm of liver and intrahepatic bile duct
0.4
7.2
35
778
G91.0
ICD-10 Finland
Communicating hydrocephalus
2.9
7.2
40
132
I49.9
ICD-10 Finland
Cardiac arrhythmia, unspecified
0.7
7.2
289
3804
F009, G301
ICD-10 Finland
NA
12.9
7.2
12
9
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
0.8
7.2
1279
14183
115
Kela drug reimbursment
Breast cancer
0.7
7.2
176
2520
SPAT1138
SPAT
Guidance concerning bowel function
1.8
7.1
106
560
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
0.7
7.1
346
4420
B01AC24
ATC
ticagrelor; oral
0.5
7.1
52
1001
E87.0
ICD-10 Finland
Hyperosmolality and hypernatraemia
2.8
7.1
42
145
F01.9
ICD-10 Finland
Vascular dementia, unspecified
1.6
7.1
158
941
I50.0
ICD-10 Finland
Congestive heart failure
0.8
7.0
496
6041
SPAT1309
SPAT
Guidance related to psychoactive substances / risk behaviour
2.0
7.0
82
398
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
0.6
7.0
84
1406
SPAT1236
SPAT
Informing family of child’s disability
1.8
7.0
119
656
8041/3-C34.9
ICD-O-3
Small cell carcinoma, NOS, of lung, NOS
0.1
6.9
*
271
P29
ICPC
Psychological sympt/compl other
1.8
6.9
117
642
SPAT1325
SPAT
Vaccination
1.2
6.9
2185
19088
F00.22
ICD-10 Finland
Dementia in Alzheimer's disease, atypical or mixed type other additional symptoms, mainly hallucinations
7.6
6.9
15
19
L08
ICPC
Shoulder symptom/complaint
0.8
6.9
562
6732
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
0.5
6.9
56
1046
F00.24
ICD-10 Finland
Dementia in Alzheimer's disease, atypical or mixed type other additional symptoms of mixed type
6.3
6.9
17
26
SPAT1104
SPAT
Monitoring of emergency patient
1.4
6.9
365
2619
G04CB02
ATC
dutasteride; oral
1.3
6.9
452
3351
-1
ICPC
NA
1.8
6.9
105
559
SPAT1262
SPAT
Handing over of treatment supplies
1.2
6.8
1025
8400
G31.1
ICD-10 Finland
Senile degeneration of brain, not elsewhere classified
4.4
6.8
23
51
P99
ICPC
Psychological disorders other
2.3
6.8
57
237
WX404
NOMESCO Finland
Intravenous generell anesthesy
0.8
6.7
543
6511
N30.9
ICD-10 Finland
Cystitis, unspecified
1.4
6.7
348
2486
PJA12
NOMESCO Finland
Sentinel node biopsy
0.6
6.7
140
2071
206
Kela drug reimbursment
Chronic coronary artery disease and dyslipidaemia associated with chronic coronary artery disease
0.8
6.7
1357
14899
F00.03
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, presenil onset other additional symptoms, mainly depression
38.6
6.6
8
*
U28
ICPC
Limited function/disability (U)
2.0
6.6
81
398
S72.1
ICD-10 Finland
Pertrochanteric fracture
1.5
6.6
211
1371
Y94.0
ICD-10 Finland
Accident at home
1.7
6.6
120
677
S00.1
ICD-10 Finland
Contusion of eyelid and periocular area
1.9
6.6
87
439
C01AA05
ATC
digoxin; systemic
0.8
6.6
607
7167
SPAT1240
SPAT
Therapeutic discussion
1.5
6.6
238
1591
WX302
NOMESCO Finland
Thoracal epidural anesthesy
0.6
6.5
97
1540
C34.3
ICD-10 Finland
Malignant neoplasm: Lower lobe, bronchus or lung
0.4
6.5
21
545
205
Kela drug reimbursment
Chronic hypertension
0.9
6.5
1935
20656
XCW99
NOMESCO Finland
Other investigative procedure of eye
0.8
6.5
436
5346
SPAT1249
SPAT
Treatment-related counselling outside office
1.2
6.5
1902
16516
S01.9
ICD-10 Finland
Open wound of head, part unspecified
1.9
6.4
90
466
N03AE01
ATC
clonazepam; systemic
1.4
6.4
248
1681
F05.9
ICD-10 Finland
Delirium, unspecified
1.6
6.4
155
946
C09CA06
ATC
candesartan; oral
0.8
6.4
736
8504
EBA30
NOMESCO Finland
Excision of root of tooth
1.4
6.4
245
1657
XF404
NOMESCO Finland
Ambulatory ECG
0.7
6.4
327
4151
H02AA02
ATC
fludrocortisone; oral
2.1
6.4
65
296
R1250
SPAT
NA
2.8
6.4
37
126
TFP20
NOMESCO Finland
Cardiodefibrillation
0.7
6.3
271
3532
8140/3-C34.9
ICD-O-3
Adenocarcinoma, NOS, of lung, NOS
0.2
6.3
8
330
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
1.4
6.3
346
2497
SPAT1153
SPAT
Removal of sutures
0.9
6.3
1303
14297
L03AA13
ATC
pegfilgrastim; parenteral
0.5
6.3
41
819
A12AA04
ATC
calcium carbonate; oral
0.3
6.3
17
474
F0004, G300
ICD-10 Finland
NA
13.8
6.3
10
7
J09
ICD-10 Finland
Influenza due to identified zoonotic or pandemic influenza virus
1.7
6.2
132
779
SPAT1285
SPAT
Provision of consultation response
1.4
6.2
279
1945
A01
ICPC
Pain general/multiple sites
1.3
6.2
398
2937
C01BD01
ATC
amiodarone; systemic
0.6
6.2
72
1216
Z51.1
ICD-10 Finland
Chemotherapy session for neoplasm
0.3
6.2
10
362
F0013, G301
ICD-10 Finland
NA
7.9
6.2
13
16
R4190
NOMESCO Finland
Nutritional therapy
0.4
6.1
18
486
SPAT1042
SPAT
Guidance concerning balance maintenance
2.4
6.1
47
188
SPAT1255
SPAT
Intravenous administration of medicine
1.4
6.1
344
2491
I25.2
ICD-10 Finland
Old myocardial infarction
0.8
6.1
401
4930
J45.9
ICD-10 Finland
Asthma, unspecified
0.8
6.1
618
7229
4100X
ICD-9 Finland
Acute myocardial infarction, Of anterolateral wall[INFARCTUS MYOCARDII ACUTUS DEFINITUS,MÄÄRITTELEMÄT]
0.6
6.0
92
1455
A04AA55
ATC
palonosetron, combinations; systemic
0.2
6.0
8
322
Mortality – FinRegistry
↥This endpoint is excluded from FinRegistry analyses (omitted endpoint).
Relationships between endpoints
↥Index endpoint: ADMED_ACHEI_DONEPEZIL – Use of donepezil
GWS hits: -
This endpoint is excluded from FinRegistry analyses (omitted endpoint).