Depression medications

ANTIDEPRESSANTS

No definition available.

Endpoint definition

FinnGen phenotype data

414262 individuals

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Apply sex-specific rule None

414262

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Check conditions None

414262

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Check pre-conditions, main-only, mode, registry filters None

0 out of 7 registries used, show all original rules.

0

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Check minimum number of events None

0

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Remove individuals based on genotype QC

106785

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ANTIDEPRESSANTS

Control definitions

Control exclude NEURO_COMORBIDITIES

Extra metadata

First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 106785 69471 37314
Unadjusted prevalence (%) 28.32 32.95 22.44
Mean age at first event (years) 45.38 43.20 49.45

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 2.09 [1.92, 2.28] 1.2e-62 10153
15 years 0.01 1.46 [1.36, 1.58] 3.2e-23 4472
5 years 0.00 2.84 [2.65, 3.04] <1e-100 2877
1 year 0.00 3.31 [2.96, 3.71] 1.7e-96 676

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: ANTIDEPRESSANTS – Depression medications
GWS hits: 37

Survival analyses between endpoints

Plot

before Depression medications
after Depression medications

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Depression medications

Not a core endpoint, no data to show.