Acute appendicitis, with complications

APPENDACUT_COMPLIC

appendicitis: Acute inflammation of the vermiform appendix.

Endpoint definition

FinnGen phenotype data

414262 individuals

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Apply sex-specific rule None

414262

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Check conditions None

414262

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 K35.0, K35.1
Hospital discharge: ICD-9 540[0-1]
Hospital discharge: ICD-8 540
Hospital discharge: excluded ICD-8 54090|54099
Cause of death: ICD-10 K35.0, K35.1
Cause of death: ICD-9 540[0-1]
Cause of death: ICD-8 540
Cause of death: excluded ICD-8 54090|54099

2 out of 7 registries used, show all original rules.

7327

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Check minimum number of events None

7327

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Include endpoints None

7327

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Remove individuals based on genotype QC

6747

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APPENDACUT_COMPLIC

Control definitions

Control exclude K11_APPENDIX

Extra metadata

First used in FinnGen datafreeze DF3

Summary Statistics

Key figures

All Female Male
Number of individuals 6747 3212 3535
Unadjusted prevalence (%) 1.79 1.52 2.13
Mean age at first event (years) 36.63 34.47 38.59

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.01 0.92 [0.68, 1.24] 5.7e-1 717
15 years 0.00 0.76 [0.59, 0.97] 3.0e-2 317
5 years 0.00 1.10 [0.86, 1.42] 4.4e-1 116
1 year 0.00 2.38 [1.69, 3.34] 5.7e-7 46

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: APPENDACUT_COMPLIC – Acute appendicitis, with complications
GWS hits: 4

Survival analyses between endpoints

Plot

before Acute appendicitis, with complications
after Acute appendicitis, with complications

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Acute appendicitis, with complications

Not a core endpoint, no data to show.