Acute appendicitis, no complications

APPENDACUT_NOCOMPLIC

appendicitis: Acute inflammation of the vermiform appendix.

Endpoint definition

FinnGen phenotype data

414262 individuals

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Apply sex-specific rule None

414262

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Check conditions

not APPENDACUT_COMPLIC

406935

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Check pre-conditions, main-only, mode, registry filters None

0 out of 7 registries used, show all original rules.

0

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Check minimum number of events None

0

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Include endpoints

23749

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Remove individuals based on genotype QC

21998

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APPENDACUT_NOCOMPLIC

Control definitions

Control exclude K11_APPENDIX
Control conditions not APPENDACUT_COMPLIC

Extra metadata

First used in FinnGen datafreeze DF3

Summary Statistics

Key figures

All Female Male
Number of individuals 21998 12364 9634
Unadjusted prevalence (%) 5.83 5.87 5.79
Mean age at first event (years) 34.21 32.44 36.49

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.06 [0.86, 1.30] 6.1e-1 1058
15 years 0.01 0.81 [0.68, 0.97] 2.5e-2 446
5 years 0.00 1.09 [0.89, 1.33] 3.9e-1 153
1 year 0.00 1.86 [1.36, 2.56] 1.3e-4 47

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: APPENDACUT_NOCOMPLIC – Acute appendicitis, no complications
GWS hits: 9

Survival analyses between endpoints

Plot

before Acute appendicitis, no complications
after Acute appendicitis, no complications

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Acute appendicitis, no complications

Not a core endpoint, no data to show.