This is a non-core endpoint: only basic statistics are computed.
See its core counterpart C3_TONSIL_EXALLC for full statistics.
Malignant neoplasm of tonsil
C3_TONSIL
tonsil cancer: Tumors or cancer of the PALATINE TONSIL.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
479 |
4. Check minimum number of eventsNone |
479 |
5. Include endpointsNone |
479 |
6. Filter based on genotype QC (FinnGen only) |
479 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF9
Similar endpoints
↥List of similar endpoints to
Malignant neoplasm of tonsil
based on the number of shared cases.
Similar with more cases:
- Malignant neoplasm of oropharynx
- Malignant neoplasm of tonsil, excluding all cancers (controls excluding all cancers)
- Malignant neoplasm of oropharynx, excluding all cancers (controls excluding all cancers)
- Malignant cancer of tonsil and base of tongue, excluding all cancers (controls excluding all cancers)
- Malignant neoplasm of head and neck
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded from FinRegistry analyses (omitted endpoint).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 479 | 149 | 330 |
| Unadjusted period prevalence (%) | 0.12 | 0.05 | 0.15 |
| Median age at first event (years) | 61.15 | 61.92 | 60.79 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 447
- Matched controls
- 4472
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
C09.0
ICD-10 Finland
Malignant neoplasm: Tonsillar fossa
+∞
268.8
230
*
8070/3-C09.9
ICD-O-3
Squamous cell carcinoma, NOS, of tonsil, NOS
+∞
268.8
230
*
C09.9
ICD-10 Finland
Malignant neoplasm: Tonsil, unspecified
+∞
180.9
161
*
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
147.0
158.0
161
17
EMB10
NOMESCO Finland
Tonsillectomy
48.1
150.6
184
64
JDB10
NOMESCO Finland
Percutaneous gastrostomy
114.5
139.8
147
19
130
Kela drug reimbursment
Malignant tumour
18.8
133.9
229
236
A03FA01
ATC
metoclopramide; systemic, rectal
13.0
125.4
282
519
C09.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of tonsil
+∞
100.9
93
*
WF002
NOMESCO Finland
Radical radiotherapy
16.5
92.0
158
143
R22.1
ICD-10 Finland
Localized swelling, mass and lump, neck
28.4
81.0
112
52
EMA10
NOMESCO Finland
Biopsy of tonsil
140.9
77.9
81
7
C77.0
ICD-10 Finland
Secondary and unspecified malignant neoplasm: Lymph nodes of head, face and neck
80.3
76.6
85
13
D10.4
ICD-10 Finland
Benign neoplasm: Tonsil
294.7
74.8
74
*
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
21.6
71.6
108
65
EP1AE
NOMESCO Finland
Neck ultrasound examination
14.2
70.5
127
121
N02AA05
ATC
oxycodone; systemic
7.0
64.8
193
435
A04AA02
ATC
granisetron; systemic, transdermal
12.7
63.4
120
125
PJD71
NOMESCO Finland
Extended sparing excision of cervical lymph nodes
85.6
60.0
66
9
8070/3-C09.0
ICD-O-3
Squamous cell carcinoma, NOS, of tonsillar fossa
+∞
55.4
52
*
YA1BD
NOMESCO Finland
Extensive CT examination of head and neck for dose design of radiotherapy
40.5
52.8
66
19
9680/3-C09.9
ICD-O-3
Diffuse large B-cell lymphoma, NOS, of tonsil, NOS
+∞
51.0
48
*
YA1VG
NOMESCO Finland
MRI examination of head and neck with high intesity magnet for dose design of radiotherapy
66.4
50.8
58
10
C83.31
ICD-10 Finland
Diffuse lymphoma with large B cells
30.1
49.9
67
26
UJC01
NOMESCO Finland
Scopy of lower throat
45.9
49.3
60
15
A04AA01
ATC
ondansetron; systemic, rectal
8.9
49.0
113
164
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
10.6
48.2
99
117
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
4.5
47.9
254
1015
EP1CG
NOMESCO Finland
Extensive MRI examination of soft tissue of neck with high intesity magnet
38.3
47.4
60
18
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
12.9
46.7
86
81
H02AB02
ATC
dexamethasone; systemic
7.0
46.0
126
236
ZX095
NOMESCO Finland
Combined chemoradiotherapy
46.1
43.6
53
13
EN1BD
NOMESCO Finland
Very extensive CT examination of mouth and soft tissues of neck
21.8
43.3
64
34
R4190
NOMESCO Finland
Nutritional therapy
13.4
42.4
76
67
WF003
NOMESCO Finland
Adjuvant radiotherapy
14.3
42.0
73
60
YA1CD
NOMESCO Finland
Very extensive CT examination of head and neck for dose design of radiotherapy
118.6
40.5
43
*
GDA98
NOMESCO Finland
Other bronchoscopic incision, excision of lesion or repair of lung
40.0
40.0
50
14
EP1DG
NOMESCO Finland
Very extensive examination of soft tissue of neck with high intesity magnet
67.7
37.9
43
7
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
8.0
37.2
90
137
A07AA02
ATC
nystatin; oral
7.9
37.0
90
138
ZX090
NOMESCO Finland
Other technic of radiotherapy
12.5
36.9
68
63
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
3.6
36.4
263
1263
JCW98
NOMESCO Finland
Other transluminal endoscopic procedure on oesophagus
+∞
34.8
33
*
UDQ12
NOMESCO Finland
Flexible laryngoscopy
7.7
34.2
84
130
UDH02
NOMESCO Finland
Rhinopharyngoscopy
7.1
33.3
87
147
JN4KR
NOMESCO Finland
Whole body very extensive metabolic PET with CT
40.8
33.1
41
11
9591/3-C09.9
ICD-O-3
Malignant lymphoma, non-Hodgkin, NOS, of tonsil, NOS
+∞
32.7
31
*
XX3DW
NOMESCO Finland
Time consuming IT work
5.1
32.6
116
288
JN5DR
NOMESCO Finland
PET-CT of upper body metabolism
23.2
32.1
46
22
SAA03
NOMESCO Finland
Extended examination of mouth
3.3
31.5
234
1105
D37.08
ICD-10 Finland
Tumor of uncertain or unknown nature in other part of lip, oral cavity and pharynx
335.2
31.2
31
*
J35.1
ICD-10 Finland
Hypertrophy of tonsils
38.7
31.1
39
11
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
7.5
30.6
76
119
PJD81
NOMESCO Finland
Excision of lymph nodes from upper part of neck
34.5
29.6
38
12
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
6.8
28.5
76
131
WD405
NOMESCO Finland
Simple antiboidy therapy of methastized malignancy
13.0
28.0
50
43
WZC10
NOMESCO Finland
Extensive specialist consultion with written report
7.7
27.7
67
100
JN4JR
NOMESCO Finland
Whole body extensive metabolic PET with CT
36.6
26.9
34
10
YA1AD
NOMESCO Finland
CT examination of head and neck for dose design of radiotherapy
25.1
26.6
37
16
GBB00
NOMESCO Finland
Tracheostomy
19.3
25.8
39
22
EBA15
NOMESCO Finland
Extraction of large number of teeth
6.8
25.4
67
113
ENB20
NOMESCO Finland
Pharyngectomy
+∞
25.2
24
*
EBA10
NOMESCO Finland
Surgical removal of tooth
4.6
23.8
90
232
ZX070
NOMESCO Finland
Intensity modified radiotherapy
11.2
23.1
44
43
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
7.2
23.1
58
91
WX408
NOMESCO Finland
General anesthesy, balanced
2.9
22.7
185
872
R13
ICD-10 Finland
Dysphagia
5.2
21.5
70
153
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
7.1
21.5
54
85
A04AD12
ATC
aprepitant; systemic
12.5
21.2
38
33
K11.70
ICD-10 Finland
Hypoptyalism
63.2
21.1
24
*
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
5.0
20.9
71
163
R59.0
ICD-10 Finland
Localized enlarged lymph nodes
8.1
20.2
46
62
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
3.8
19.9
92
284
WD415
NOMESCO Finland
Demanding antibody therapy of methastized malignancy
11.1
19.5
37
36
ENA10
NOMESCO Finland
Biopsy of pharynx
48.3
19.4
23
5
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
4.3
19.2
75
198
UJC02
NOMESCO Finland
Rigid oesophagoscopy
22.0
18.8
27
13
WZC05
NOMESCO Finland
Specialty-specific consultation based on referral by dentist or doctor
5.9
18.1
52
98
R07.0
ICD-10 Finland
Pain in throat
5.9
17.7
51
96
WB101
NOMESCO Finland
Simple cytostatic neoadjuvant therapy
99.0
17.7
19
*
WZC30
NOMESCO Finland
Teaching
3.2
17.5
103
379
EJA10
NOMESCO Finland
Biopsy of tongue or floor of mouth
9.6
17.2
35
39
JN6AD
NOMESCO Finland
CT of torso and neck
14.0
17.2
29
22
H03AA01
ATC
levothyroxine sodium; systemic
2.9
17.2
122
511
WW500
NOMESCO Finland
Blood transfusion
5.7
16.8
49
94
ENB00
NOMESCO Finland
Excision or exploration of lesion of pharynx
+∞
16.8
16
*
9673/3-C09.9
ICD-O-3
Mantle cell lymphoma of tonsil, NOS
+∞
16.8
16
*
SBB10
NOMESCO Finland
Teeth copy
5.3
16.0
50
104
L03AA02
ATC
filgrastim; parenteral
7.1
16.0
39
59
PJD51
NOMESCO Finland
Block dissection of cervical lymph nodes
62.3
15.9
18
*
ZZQ00
NOMESCO Finland
Free microvascular graft of skin
27.4
15.7
21
8
SCA04
NOMESCO Finland
Guidance on care of mouth and oral mucosa
33.0
14.9
19
6
SCA02
NOMESCO Finland
Analysis and advice of nutrition with regard to dentistry
4.0
14.9
62
173
PJ3AT
NOMESCO Finland
Cytology of lymphnode with ultrasound guidance
26.1
14.8
20
8
GD1AD
NOMESCO Finland
Thorax CT examination
5.4
14.8
45
91
C09
ICD-10 Finland
Malignant neoplasm of tonsil
+∞
14.7
14
*
EMB00
NOMESCO Finland
Excision of lesion of tonsil or adenoids
+∞
14.7
14
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.2
14.4
240
1544
C85.9
ICD-10 Finland
Non-Hodgkin lymphoma, unspecified
20.0
14.4
21
11
JN4BD
NOMESCO Finland
Extensive body CT
3.0
14.2
91
352
K04.5
ICD-10 Finland
Chronic apical periodontitis
2.4
13.9
150
784
WX002
NOMESCO Finland
Sedation and analgesia
2.6
13.6
118
547
TJD20
NOMESCO Finland
Change of gastrostomy tube
35.2
13.6
17
5
WX402
NOMESCO Finland
General anaesthesia
2.7
13.2
101
435
ZX120
NOMESCO Finland
Intravenous
3.3
12.8
67
225
A02BC05
ATC
esomeprazole; systemic
2.1
12.8
205
1274
C83.1
ICD-10 Finland
Mantle cell lymphoma
16.0
12.7
20
13
L03AA13
ATC
pegfilgrastim; parenteral
5.9
12.7
35
63
D70.82
ICD-10 Finland
Drug-induced neutropenia
9.1
12.7
26
30
C01
ICD-10 Finland
Malignant neoplasm of base of tongue
72.0
12.7
14
*
ENB40
NOMESCO Finland
Excision of branchial cyst or fistula
72.0
12.7
14
*
T05
ICPC
Feeding problem of adult
33.1
12.6
16
5
K05.31
ICD-10 Finland
Periodontitis pronounced
3.0
12.6
76
283
C09.1
ICD-10 Finland
Malignant neoplasm: Tonsillar pillar (anterior)(posterior)
+∞
12.6
12
*
YX9BD
NOMESCO Finland
Other extensive CT eamination for dose design of radiotherapy
12.1
12.4
22
19
A06AD11
ATC
lactulose; oral
2.7
12.3
93
398
RD160
NOMESCO Finland
NA
48.0
11.9
14
*
SAA04
NOMESCO Finland
Special inverstigation of mouth
4.4
11.9
43
105
Z43.1
ICD-10 Finland
Attention to gastrostomy
123.1
11.5
12
*
EB1BI
NOMESCO Finland
Cone beam imaging of teeth and jaws (1–2 quarters)
10.0
11.4
22
23
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.9
11.1
71
274
Q18.0
ICD-10 Finland
Sinus, fistula and cyst of branchial cleft
44.5
11.0
13
*
EP1BG
NOMESCO Finland
MRI examination of soft tissue of neck with high intesity magnet
44.5
11.0
13
*
TDW99
NOMESCO Finland
Other minor procedure in surgery of ear, nose and larynx
5.4
10.8
32
63
Z51.5
ICD-10 Finland
Palliative care
3.6
10.7
48
143
PJD41
NOMESCO Finland
Excision of cervical lymph nodes
8.8
10.7
22
26
SXB00
NOMESCO Finland
Removeal of sutres from oral mucosa
4.1
10.6
41
107
SCA03
NOMESCO Finland
Preventive oral health care, extensive
4.7
10.5
35
79
ENB99
NOMESCO Finland
Other excision of pharynx and adjacent structures
112.6
10.5
11
*
EB1BA
NOMESCO Finland
Extensive intraoral X-ray examination
24.0
10.3
14
6
WX110
NOMESCO Finland
Local anesthesy
2.0
10.1
309
2376
EB1WA
NOMESCO Finland
NA
11.7
10.1
18
16
J02AC01
ATC
fluconazole; systemic
2.1
10.1
150
882
ZXE50
NOMESCO Finland
More than nine and less than 12 hours
9.5
10.1
20
22
EN1AD
NOMESCO Finland
CT examination of mouth and soft tissues of neck
10.4
10.1
19
19
RD210
NOMESCO Finland
NA
7.9
10.0
22
29
XW000
NOMESCO Finland
Bone marrow biopsy
3.9
9.8
40
110
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
6.2
9.7
25
42
UDQ22
NOMESCO Finland
Microlaryngoscopy
11.7
9.6
17
15
JN6BD
NOMESCO Finland
Extensive CT of torso and neck
11.7
9.6
17
15
A04AA55
ATC
palonosetron, combinations; systemic
5.6
9.5
27
51
QA1S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in head
18.0
9.5
14
8
EP1CM
NOMESCO Finland
Extensive MRI examination of soft tissue of neck with 3 Tesla magnet
102.1
9.4
10
*
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
2.9
9.4
59
224
8085/3-C09.9
ICD-O-3
Squamous cell carcinoma, HPV positive of tonsil, NOS
+∞
9.4
9
*
1460A
ICD-9 Finland
Malignant neoplasm of oropharynx, Tonsil
+∞
9.4
9
*
UJC20
NOMESCO Finland
Extensive endoscopy to identify diagnosed or suspected primary malignant neoplasm of head or neck
+∞
9.4
9
*
OAB73
NOMESCO Finland
Prevention and treatment of malnutrition
14.1
9.2
15
11
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
4.0
9.2
36
96
SXC03
NOMESCO Finland
Other oral or dental procedure
9.3
9.1
18
20
UGC12
NOMESCO Finland
Flexible bronchoscopy
2.9
9.0
56
211
SBB00
NOMESCO Finland
Fotograf of mouth and teeth
4.7
9.0
30
68
EBA12
NOMESCO Finland
Complicated surgical removal of tooth
7.1
8.9
21
31
R22.0
ICD-10 Finland
Localized swelling, mass and lump, head
5.0
8.7
27
57
K05.30
ICD-10 Finland
Periodontitis complex
2.4
8.7
75
343
Z51.1
ICD-10 Finland
Chemotherapy session for neoplasm
7.6
8.5
19
26
Z3226
NOMESCO Finland
Physiotherapist
2.1
8.5
101
536
EB1AI
NOMESCO Finland
Cone beam imaging of teeth and jaws (one quarter)
6.9
8.5
20
30
J35.9
ICD-10 Finland
Chronic disease of tonsils and adenoids, unspecified
91.7
8.4
9
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.9
8.3
146
902
SBA00
NOMESCO Finland
Microbiological examinations
5.3
8.3
24
47
N05CF01
ATC
zopiclone; oral
1.9
8.2
148
923
N02AJ06
ATC
codeine and paracetamol; systemic
1.8
8.2
174
1147
WW300
NOMESCO Finland
Transfer of autologic stem cells
17.6
8.1
12
7
D37.09
ICD-10 Finland
Lip, oral cavity and pharynx
34.0
8.1
10
*
XW1AT
NOMESCO Finland
Biopsy from other organ close to skin with ultrasound quidance
13.3
7.9
13
10
UDQ02
NOMESCO Finland
Direct laryngoscopy
11.1
7.8
14
13
K02.1
ICD-10 Finland
Caries of dentine
1.8
7.8
244
1816
R4130
NOMESCO Finland
Speech therapy
6.1
7.8
20
34
SPA00
NOMESCO Finland
Changing form of teeth in prepation for prothetic work
3.4
7.8
37
117
JN4DR
NOMESCO Finland
Whole body metabolic PET with CT
25.5
7.6
10
*
EB1JA
NOMESCO Finland
Double panorama tomography of teeth and jaws or similar X-ray examination
9.1
7.6
15
17
EBA00
NOMESCO Finland
Extraction of tooth
1.8
7.6
153
987
WX199
NOMESCO Finland
Other local analgesia
5.0
7.6
23
48
A02BC02
ATC
pantoprazole; systemic
1.8
7.5
294
2328
ZXE00
NOMESCO Finland
One hour or less
1.8
7.5
183
1257
K10.26
ICD-10 Finland
Periostitis of jaw (acute)(chronic)(suppurative)
81.4
7.4
8
*
R22.9
ICD-10 Finland
Localized swelling, mass and lump, unspecified
3.2
7.4
38
127
PJA10
NOMESCO Finland
Exploration of lymph nodes
7.0
7.4
17
25
R04.1
ICD-10 Finland
Haemorrhage from throat
+∞
7.3
7
*
TPH04
NOMESCO Finland
Cathetrisation of vein
2.0
7.3
107
614
K12.10
ICD-10 Finland
Stomatitis NOS
30.5
7.2
9
*
XQ902
NOMESCO Finland
Other photography
20.4
7.2
10
5
SBA10
NOMESCO Finland
Measurement of excretion of saliva
12.3
7.1
12
10
C83.9
ICD-10 Finland
Non-follicular (diffuse) lymphoma, unspecified
12.3
7.1
12
10
K11.2
ICD-10 Finland
Sialoadenitis
4.6
7.1
23
52
WD135
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
7.7
7.0
15
20
EBB15
NOMESCO Finland
Insertion of dental implant abutment
9.5
6.8
13
14
UGC02
NOMESCO Finland
Rigid bronchoscopy
40.7
6.8
8
*
EE1AA
NOMESCO Finland
X-ray of upper jaw or palate
17.0
6.8
10
6
YX9AD
NOMESCO Finland
Other CT eamination for dose design of radiotherapy
5.1
6.7
20
41
C83.39
ICD-10 Finland
Diffuse non-Hodgkin's large cell lymphoma UNS
22.9
6.7
9
*
K03.28
ICD-10 Finland
Other erosion of teeth
8.0
6.7
14
18
Z2446
NOMESCO Finland
Social worker
2.8
6.6
40
150
SDA02
NOMESCO Finland
Parodonthologic therapy
1.8
6.6
137
885
ED1AA
NOMESCO Finland
Mandipular X-ray examination
7.6
6.5
14
19
D10.9
ICD-10 Finland
Benign neoplasm: Pharynx, unspecified
70.8
6.4
7
*
R11
ICD-10 Finland
Nausea and vomiting
2.9
6.4
37
134
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.9
6.3
98
572
C83.3
ICD-10 Finland
Diffuse large B-cell lymphoma
18.3
6.3
9
5
ZXF99
NOMESCO Finland
Other r3eason to interrupt procedure
18.3
6.3
9
5
8072/3-C09.9
ICD-O-3
Squamous cell carcinoma, large cell, nonkeratinizing, NOS, of tonsil, NOS
+∞
6.3
6
*
8083/3-C09.9
ICD-O-3
Basaloid squamous cell carcinoma of tonsil, NOS
+∞
6.3
6
*
EP1DM
NOMESCO Finland
Very extensive MRI examination of soft tissue of neck with 3 Tesla magnet
+∞
6.3
6
*
9691/3-C09.9
ICD-O-3
Follicular lymphoma, grade 2 of tonsil, NOS
+∞
6.3
6
*
ZXD10
NOMESCO Finland
Scheduled procedure
1.7
6.2
178
1263
SCA01
NOMESCO Finland
Simple analysis and advice of nutrition with regard to dentistry
1.8
6.2
110
676
J01CE02
ATC
phenoxymethylpenicillin; oral
1.7
6.1
289
2344
K11.71
ICD-10 Finland
Xerostomy (dry mouth)
12.7
6.1
10
8
H02AB06
ATC
prednisolone; systemic
1.6
6.1
202
1491
Mortality – FinRegistry
↥This endpoint is excluded from FinRegistry analyses (omitted endpoint).
Relationships between endpoints
↥Index endpoint: C3_TONSIL – Malignant neoplasm of tonsil
GWS hits: -
This endpoint is excluded from FinRegistry analyses (omitted endpoint).