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Follicular lymphoma, hilmo

CD2_FOLLICULAR_LYMPHOMA

neoplasm of mature B-cells: A neoplasm of follicle centre B cells which has at least a partial follicular pattern. Follicular lymphomas comprise about 35% of adult non-Hodgkin lymphomas in the U.S. and 22% worldwide. Most patients have widespread disease at diagnosis. Morphologically, follicular lymphomas are classified as Grade 1, Grade 2, and Grade 3, depending on the percentage of the large lymphocytes present. The vast majority of cases (70-95%) express the BCL-2 rearrangement [t(14;18)]. Histological grade correlates with prognosis. Grades 1 and 2 follicular lymphomas are indolent and grade 3 is more aggressive (adapted from WHO, 2001).

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Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 C82
  • Hospital discharge: ICD-9 2000A
  • Cause of death: ICD-10 C82
  • Cause of death: ICD-9 2000A

2 out of 7 registries used, show all original rules.

1488

4. Check minimum number of events

None

1488

5. Include endpoints

None

1488

6. Filter based on genotype QC (FinnGen only)

1488

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF12
Parent code in ICD-10
C81-C96
Name in latin
Lymphoma non-Hodgkin nodulare (folliculare)

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 1488 758 730
Unadjusted period prevalence (%) 0.29 0.26 0.32
Median age at first event (years) 64.01 63.06 65.00

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1340
Matched controls
13400
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
C82.9
ICD-10 Finland
Follicular lymphoma, unspecified
+∞
323.0
354
*
XW000
NOMESCO Finland
Bone marrow biopsy
26.5
323.0
489
284
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
79.1
323.0
867
303
C82.1
ICD-10 Finland
Follicular lymphoma grade II
+∞
323.0
745
*
C82.01
ICD-10 Finland
Follicular nodular lymphoma, grade I
+∞
323.0
339
*
C82.2
ICD-10 Finland
Follicular lymphoma grade III, unspecified
+∞
316.6
291
*
R59.0
ICD-10 Finland
Localized enlarged lymph nodes
42.6
314.8
395
130
WD405
NOMESCO Finland
Simple antiboidy therapy of methastized malignancy
43.7
300.7
375
118
C82.00
ICD-10 Finland
Follicular nodular non-Hodgkin's lymphoma, ungraded
+∞
299.5
276
*
JN4BD
NOMESCO Finland
Extensive body CT
9.5
240.0
580
994
PJD41
NOMESCO Finland
Excision of cervical lymph nodes
67.6
239.9
275
51
L03AA02
ATC
filgrastim; parenteral
25.3
216.3
312
159
PJA10
NOMESCO Finland
Exploration of lymph nodes
60.1
203.4
238
48
M04AA01
ATC
allopurinol; systemic
7.5
200.3
573
1213
R59.1
ICD-10 Finland
Generalized enlarged lymph nodes
51.2
200.1
241
57
C83.31
ICD-10 Finland
Diffuse lymphoma with large B cells
44.0
195.6
243
67
A03FA01
ATC
metoclopramide; systemic, rectal
6.2
189.0
665
1829
WD415
NOMESCO Finland
Demanding antibody therapy of methastized malignancy
29.0
174.3
240
100
9691/3-C77.9
ICD-O-3
Follicular lymphoma, grade 2 of lymph node, NOS
1903.0
170.5
162
*
C85.9
ICD-10 Finland
Non-Hodgkin lymphoma, unspecified
120.6
166.8
178
17
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
11.8
143.2
281
295
L03AA13
ATC
pegfilgrastim; parenteral
14.1
139.8
250
214
JN6AD
NOMESCO Finland
CT of torso and neck
36.7
136.2
176
55
PJD45
NOMESCO Finland
Excision of inguinal lymph nodes
90.0
117.6
130
16
1XC02
NOMESCO Finland
NA
44.3
109.9
136
34
JN4AD
NOMESCO Finland
Body CT examination
6.4
107.3
316
618
ZX120
NOMESCO Finland
Intravenous
5.6
98.4
324
721
A04AA02
ATC
granisetron; systemic, transdermal
7.0
97.9
263
449
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
8.9
97.9
222
292
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
7.4
96.1
248
399
A04AA01
ATC
ondansetron; systemic, rectal
6.5
89.9
256
470
JN6BD
NOMESCO Finland
Extensive CT of torso and neck
35.2
89.2
116
36
R59.9
ICD-10 Finland
Enlarged lymph nodes, unspecified
41.6
88.6
111
29
C83.9
ICD-10 Finland
Non-follicular (diffuse) lymphoma, unspecified
107.1
83.0
90
9
WD135
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
30.3
80.8
109
39
EP1AE
NOMESCO Finland
Neck ultrasound examination
7.0
80.0
212
349
9691/3-C77.8
ICD-O-3
Follicular lymphoma, grade 2 of lymph nodes of multiple regions
+∞
73.6
70
*
R22.1
ICD-10 Finland
Localized swelling, mass and lump, neck
9.5
72.4
155
181
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.8
68.5
335
1068
XZZ00
NOMESCO Finland
Active surveillance of a diagnosed cancer
16.9
66.6
108
69
9690/3-C77.9
ICD-O-3
Follicular lymphoma, NOS, of lymph node, NOS
+∞
66.2
63
*
9680/3-C77.9
ICD-O-3
Diffuse large B-cell lymphoma, NOS, of lymph node, NOS
93.7
64.6
71
8
Z51.1
ICD-10 Finland
Chemotherapy session for neoplasm
16.0
63.4
105
71
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
2.8
63.1
604
3072
9698/3-C77.9
ICD-O-3
Follicular lymphoma, grade 3 of lymph node, NOS
+∞
63.0
60
*
C82.7
ICD-10 Finland
Other types of follicular lymphoma
+∞
59.8
57
*
EN1BD
NOMESCO Finland
Very extensive CT examination of mouth and soft tissues of neck
12.8
58.3
106
89
WW500
NOMESCO Finland
Blood transfusion
6.7
56.3
151
248
D70.82
ICD-10 Finland
Drug-induced neutropenia
12.7
56.0
102
86
C85.1
ICD-10 Finland
B-cell lymphoma, unspecified
37.4
55.6
71
20
9695/3-C77.9
ICD-O-3
Follicular lymphoma, grade 1 of lymph node, NOS
+∞
55.6
53
*
PJ2AT
NOMESCO Finland
Biopsy of lymphnode with ultrasound guidance
23.6
55.5
80
36
H02AB06
ATC
prednisolone; systemic
2.5
55.5
782
4824
R50.9
ICD-10 Finland
Fever, unspecified
3.4
55.2
309
1077
L03AA14
ATC
lipegfilgrastim; parenteral
12.1
53.5
100
89
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
5.3
51.6
170
360
9691/3-C42.1
ICD-O-3
Follicular lymphoma, grade 2 of bone marrow
+∞
50.3
48
*
C83.39
ICD-10 Finland
Diffuse non-Hodgkin's large cell lymphoma UNS
56.0
50.0
59
11
ZX112
NOMESCO Finland
Subcutaneous
8.7
49.7
111
138
WF049
NOMESCO Finland
Radiotherapy of metastasis
6.6
48.6
131
216
A49.9
ICD-10 Finland
Bacterial infection, unspecified
3.3
45.8
260
903
WF002
NOMESCO Finland
Radical radiotherapy
4.6
44.2
164
393
WD115
NOMESCO Finland
Multiple cystostatic therapy of methastized malignancy
10.1
44.1
90
95
H02AB07
ATC
prednisone; oral
2.9
43.1
299
1191
C81.1
ICD-10 Finland
Nodular sclerosis classical Hodgkin lymphoma
63.5
42.5
49
8
L01AA02
ATC
chlorambucil; oral
35.1
41.9
54
16
C83.00
ICD-10 Finland
Lymphocytic lymphoma
44.1
41.5
51
12
JN4JR
NOMESCO Finland
Whole body extensive metabolic PET with CT
15.6
40.5
67
45
C83.1
ICD-10 Finland
Mantle cell lymphoma
39.9
39.9
50
13
B72
ICPC
Hodgkin Lymphoma
140.8
38.9
41
*
2000A
ICD-9 Finland
Lymphosarcoma and reticulosarcoma, Reticulosarcoma[LYMPHOMA MALIGNUM FOLLICULARE]
+∞
38.7
37
*
9698/3-C77.8
ICD-O-3
Follicular lymphoma, grade 3 of lymph nodes of multiple regions
+∞
38.7
37
*
H02AB02
ATC
dexamethasone; systemic
3.0
37.5
240
896
C81.9
ICD-10 Finland
Hodgkin lymphoma, unspecified
46.5
37.1
45
10
WF004
NOMESCO Finland
Palliative radiotherapy
8.7
37.1
82
100
PJD42
NOMESCO Finland
Excision of axillary lymph nodes
13.3
36.9
65
51
JN5DR
NOMESCO Finland
PET-CT of upper body metabolism
9.8
36.9
76
82
J05AB11
ATC
valaciclovir; oral
2.9
35.6
252
1005
C82.0
ICD-10 Finland
Follicular lymphoma grade I
+∞
35.6
34
*
212
Kela drug reimbursment
Gout
7.6
35.3
85
119
2008X
ICD-9 Finland
Lymphosarcoma and reticulosarcoma, Other named variants
184.8
34.9
36
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.0
34.4
706
4727
NEA10
NOMESCO Finland
Exploration of soft tissue of pelvis, percutaneous
37.0
33.9
43
12
C82
ICD-10 Finland
Follicular lymphoma
+∞
33.5
32
*
JN4ED
NOMESCO Finland
Body CT examination with specail preparation
119.7
32.8
35
*
XX3DW
NOMESCO Finland
Time consuming IT work
2.9
31.5
215
832
TPJ00
NOMESCO Finland
Biopsy of superficial lymph node
51.3
29.5
35
7
1AA09
NOMESCO Finland
NA
105.7
28.8
31
*
N02AA05
ATC
oxycodone; systemic
2.4
28.6
276
1300
WW300
NOMESCO Finland
Transfer of autologic stem cells
24.2
28.4
40
17
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
5.7
28.3
84
156
C83.3
ICD-10 Finland
Diffuse large B-cell lymphoma
31.7
28.2
37
12
9591/3-C77.9
ICD-O-3
Malignant lymphoma, non-Hodgkin, NOS, of lymph node, NOS
148.1
27.7
29
*
J01MA12
ATC
levofloxacin; systemic
2.2
27.5
325
1684
JN4CD
NOMESCO Finland
Very extensive body CT
4.2
27.3
109
278
A02BC02
ATC
pantoprazole; systemic
1.9
27.0
922
7162
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
5.2
27.0
86
174
EN1AD
NOMESCO Finland
CT examination of mouth and soft tissues of neck
11.2
27.0
51
47
9695/3-C77.8
ICD-O-3
Follicular lymphoma, grade 1 of lymph nodes of multiple regions
+∞
26.1
25
*
9591/3-C77.4
ICD-O-3
Malignant lymphoma, non-Hodgkin, NOS, of lymph nodes of inguinal region or leg
265.5
25.8
26
*
C83.89
ICD-10 Finland
Other types of diffuse non-Hodgkin's lymphoma
137.7
25.7
27
*
9591/3-C77.0
ICD-O-3
Malignant lymphoma, non-Hodgkin, NOS, of lymph nodes of head, face and neck
71.3
24.9
28
*
JA1AE
NOMESCO Finland
Ultrasound examination of groin and abdominal wall
7.3
24.8
60
85
PJ3AT
NOMESCO Finland
Cytology of lymphnode with ultrasound guidance
10.8
23.9
46
44
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
3.2
23.8
130
430
TPH04
NOMESCO Finland
Cathetrisation of vein
2.1
23.7
331
1830
C81.2
ICD-10 Finland
Mixed cellularity classical Hodgkin lymphoma
127.3
23.7
25
*
D70.89
ICD-10 Finland
Neutropenic splenomegaly
8.9
23.4
50
58
9591/3-C77.2
ICD-O-3
Malignant lymphoma, non-Hodgkin, NOS, of intra-abdominal lymph nodes
+∞
23.0
22
*
JAL01
NOMESCO Finland
Laparoscopic biopsy of peritoneum
32.9
22.5
29
9
YNB10
NOMESCO Finland
Collection of stem cells for transplant
35.7
22.1
28
8
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
4.2
22.0
86
215
A07AA02
ATC
nystatin; oral
3.1
22.0
130
454
C83.2
ICD-10 Finland
Mixed small and large cell (diffuse) non-Hodgkin's lymphoma
+∞
21.9
21
*
TNE25
NOMESCO Finland
Drill biopsy of bone marrow, pelvis
7.1
21.9
54
79
WD305
NOMESCO Finland
Simple therapy of methastized malignancy with biomodifiers
7.5
21.9
52
72
9690/3-C77.8
ICD-O-3
Follicular lymphoma, NOS, of lymph nodes of multiple regions
223.5
21.7
22
*
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
2.6
21.4
171
720
TPX10
NOMESCO Finland
Implantation of vascular injection port
4.4
20.7
77
184
C83.80
ICD-10 Finland
B-cell lymphoma in marginal zone
16.1
20.6
33
21
JAH20
NOMESCO Finland
Staging laparotomy
213.1
20.6
21
*
A41.9
ICD-10 Finland
Sepsis, unspecified
4.0
20.5
84
220
TGC00
NOMESCO Finland
Bronchial lavation
5.1
20.4
65
132
D69.6
ICD-10 Finland
Thrombocytopenia, unspecified
6.3
20.3
54
88
J05AB01
ATC
aciclovir; systemic
2.0
20.2
301
1692
9691/3-C77.0
ICD-O-3
Follicular lymphoma, grade 2 of lymph nodes of head, face and neck
+∞
19.8
19
*
9690/3-C77.4
ICD-O-3
Follicular lymphoma, NOS, of lymph nodes of inguinal region or leg
+∞
19.8
19
*
C96.9
ICD-10 Finland
Malignant neoplasm of lymphoid, haematopoietic and related tissue, unspecified
74.6
19.7
22
*
ZX108
NOMESCO Finland
Inhalation
12.9
19.4
34
27
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.9
19.1
363
2227
2000B
ICD-9 Finland
Lymphosarcoma and reticulosarcoma, Reticulosarcoma[LYMPHOMA MALIGNUM DIFFUSUM]
+∞
18.8
18
*
JAH01
NOMESCO Finland
Laparoscopy
3.8
18.5
80
220
WZC30
NOMESCO Finland
Teaching
2.2
18.5
215
1086
PJ2AE
NOMESCO Finland
Lymphnode ultrasound examination
8.2
18.1
40
50
WF003
NOMESCO Finland
Adjuvant radiotherapy
3.6
17.8
81
233
Z08.7
ICD-10 Finland
Follow-up examination after combined treatment for malignant neoplasm
11.2
17.8
33
30
C83.01
ICD-10 Finland
Lymphoplasmacytic lymphoma
96.3
17.6
19
*
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
3.4
17.4
85
259
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.6
16.9
628
4680
B02
ICPC
Lymph gland(s) enlarged/painful
14.3
16.8
28
20
C81.0
ICD-10 Finland
Nodular lymphocyte predominant Hodgkin lymphoma
64.2
16.8
19
*
L04.0
ICD-10 Finland
Acute lymphadenitis of face, head and neck
9.9
16.7
33
34
9690/3-C42.1
ICD-O-3
Follicular lymphoma, NOS, of bone marrow
+∞
16.7
16
*
I88.9
ICD-10 Finland
Nonspecific lymphadenitis, unspecified
16.5
16.6
26
16
YNB00
NOMESCO Finland
Excision of bone marrow for transplantation
172.0
16.5
17
*
JAH21
NOMESCO Finland
Staging laparoscopy
172.0
16.5
17
*
D47.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified
13.6
16.5
28
21
XX9CD
NOMESCO Finland
Very extensive complementary CT
30.4
16.1
21
7
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.8
16.1
334
2092
WX408
NOMESCO Finland
General anesthesy, balanced
1.7
15.9
395
2614
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
2.9
15.9
100
361
9690/3-C77.0
ICD-O-3
Follicular lymphoma, NOS, of lymph nodes of head, face and neck
+∞
15.7
15
*
QX3AT
NOMESCO Finland
Ultrasound guided biopsy of subcutaneous tissue
11.0
15.5
29
27
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
2.8
15.4
102
382
N13.3
ICD-10 Finland
Other and unspecified hydronephrosis
5.1
15.4
48
96
ZX070
NOMESCO Finland
Intensity modified radiotherapy
4.4
15.4
56
132
XW1AT
NOMESCO Finland
Biopsy from other organ close to skin with ultrasound quidance
12.5
15.4
27
22
WW409
NOMESCO Finland
Other aferesis
20.3
15.1
22
11
ZXE00
NOMESCO Finland
One hour or less
1.6
14.9
530
3861
YA1BD
NOMESCO Finland
Extensive CT examination of head and neck for dose design of radiotherapy
7.2
14.3
34
48
B01AB05
ATC
enoxaparin; parenteral
1.6
14.2
442
3097
D11.0
ICD-10 Finland
Benign neoplasm: Parotid gland
5.1
14.2
44
88
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
2.2
14.1
146
697
PH1AE
NOMESCO Finland
Ultrasound examination of upper extremity veins
5.5
13.8
40
74
9680/3-C77.8
ICD-O-3
Diffuse large B-cell lymphoma, NOS, of lymph nodes of multiple regions
20.3
13.8
20
10
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
2.6
13.8
106
433
QX3HE
NOMESCO Finland
Ultrsound examination of lesion close to skin
6.5
13.7
35
55
N02BE01
ATC
paracetamol; systemic, rectal
1.8
13.5
1139
10209
J17.3*B59
ICD-10 Finland
Pneumonia due to Pneumocystis carinii
16.4
13.5
21
13
R22.0
ICD-10 Finland
Localized swelling, mass and lump, head
3.5
13.4
63
187
Z94.8
ICD-10 Finland
Other transplanted organ and tissue status
11.6
13.3
24
21
UGC12
NOMESCO Finland
Flexible bronchoscopy
2.3
13.3
133
623
XW3AT
NOMESCO Finland
Biopsy of other superficial organ with ultrasound guidance
14.0
13.3
22
16
C83.0
ICD-10 Finland
Small cell B-cell lymphoma
131.2
12.5
13
*
FM1FN
NOMESCO Finland
Heart function isotope examination
11.7
12.3
22
19
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.6
12.3
424
3028
D80.1
ICD-10 Finland
Nonfamilial hypogammaglobulinaemia
14.5
12.3
20
14
C85.7
ICD-10 Finland
Other specified types of non-Hodgkin lymphoma
37.9
12.2
15
*
YJ1BD
NOMESCO Finland
Extensive CT examination of abdomen for dose design of radiotherapy
16.0
12.2
19
12
C92.0
ICD-10 Finland
Acute myeloblastic leukaemia [AML]
11.2
12.0
22
20
ZX090
NOMESCO Finland
Other technic of radiotherapy
3.5
12.0
56
166
WX110
NOMESCO Finland
Local anesthesy
1.5
11.8
840
7053
Z01.8
ICD-10 Finland
Other specified special examinations
1.7
11.7
285
1850
WD315
NOMESCO Finland
Multiple therapy of methastized malignancy with biomodifiers
19.1
11.6
17
9
JAH00
NOMESCO Finland
Laparotomy
3.5
11.5
54
161
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
2.0
11.5
153
813
9698/3-C77.0
ICD-O-3
Follicular lymphoma, grade 3 of lymph nodes of head, face and neck
+∞
11.5
11
*
9690/3-C77.2
ICD-O-3
Follicular lymphoma, NOS, of intra-abdominal lymph nodes
+∞
11.5
11
*
C83.32
ICD-10 Finland
Centroblastic diffuse non-Hodgkin's lymphoma
+∞
11.5
11
*
9695/3-C77.4
ICD-O-3
Follicular lymphoma, grade 1 of lymph nodes of inguinal region or leg
+∞
11.5
11
*
9695/3-C77.0
ICD-O-3
Follicular lymphoma, grade 1 of lymph nodes of head, face and neck
+∞
11.5
11
*
Z85.7
ICD-10 Finland
Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues
121.0
11.4
12
*
C81.7
ICD-10 Finland
Other classical Hodgkin lymphoma
121.0
11.4
12
*
R22.9
ICD-10 Finland
Localized swelling, mass and lump, unspecified
2.4
11.4
99
435
XW4AT
NOMESCO Finland
Biopsy of other inner organ with ultrasound guidance
10.6
11.3
21
20
TPX15
NOMESCO Finland
Removal of vascular injection port
10.6
11.3
21
20
XW4XT
NOMESCO Finland
Biopsy of other inner organ with radiological guidance guidance
35.3
11.3
14
*
B02.9
ICD-10 Finland
Zoster without complication
2.4
11.3
94
404
YA1AD
NOMESCO Finland
CT examination of head and neck for dose design of radiotherapy
6.3
10.9
28
45
4701
FHL
Neck lymph node removal
43.7
10.9
13
*
JN3BD
NOMESCO Finland
Extensive abdominal CT
1.9
10.8
157
863
B25.9
ICD-10 Finland
Cytomegaloviral disease, unspecified
18.0
10.7
16
9
YJ1AD
NOMESCO Finland
CT examination of abdomen for dose design of radiotherapy
18.0
10.7
16
9
D80.8
ICD-10 Finland
Other immunodeficiencies with predominantly antibody defects
21.6
10.7
15
7
120
Kela drug reimbursment
Hypogammaglobulinaemia
21.6
10.7
15
7
TDM10
NOMESCO Finland
Puncture of maxillary antrum
2.9
10.6
62
217
WX402
NOMESCO Finland
General anaesthesia
1.8
10.6
209
1271
J01MA14
ATC
moxifloxacin; systemic
2.0
10.5
135
706
9691/3-C77.4
ICD-O-3
Follicular lymphoma, grade 2 of lymph nodes of inguinal region or leg
+∞
10.4
10
*
9695/3-C42.1
ICD-O-3
Follicular lymphoma, grade 1 of bone marrow
+∞
10.4
10
*
D37.00
ICD-10 Finland
Aryepiglottic fold marginal zone
16.2
10.4
16
10
2009X
ICD-9 Finland
Lymphosarcoma and reticulosarcoma[LYMPHOMA MALIGNUM (NON-HODGKIN) NUD]
32.8
10.3
13
*
9680/3-C42.1
ICD-O-3
Diffuse large B-cell lymphoma, NOS, of bone marrow
32.8
10.3
13
*
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
1.9
10.2
156
870
Z51.5
ICD-10 Finland
Palliative care
2.2
10.1
103
490
ELB40
NOMESCO Finland
Partial parotidectomy
5.6
10.0
28
51
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.6
10.0
321
2235
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.7
9.8
236
1518
L01BB05
ATC
fludarabine; systemic
20.2
9.8
14
7
J06BA01
ATC
immunoglobulins, normal human, for extravascular adm.; systemic
20.2
9.8
14
7
J35.1
ICD-10 Finland
Hypertrophy of tonsils
9.6
9.8
19
20
PJD43
NOMESCO Finland
Excision of aortic lymph nodes
55.4
9.7
11
*
9591/3-C77.8
ICD-O-3
Malignant lymphoma, non-Hodgkin, NOS, of lymph nodes of multiple regions
+∞
9.4
9
*
9698/3-C42.1
ICD-O-3
Follicular lymphoma, grade 3 of bone marrow
+∞
9.4
9
*
9691/3-C07.9
ICD-O-3
Follicular lymphoma, grade 2 of parotid gland
+∞
9.4
9
*
D37.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other digestive organs
3.0
9.3
53
183
WD325
NOMESCO Finland
Demanding therapy of methastized malignancy with biomodifiers
5.5
9.2
26
48
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.5
9.1
417
3131
L03AA04
ATC
NA
36.9
9.0
11
*
372
Kela drug reimbursment
Idelalisib
36.9
9.0
11
*
PJ2HT
NOMESCO Finland
Biopsy of deep lymphnode with ultrasound guidance
36.9
9.0
11
*
AA1BD
NOMESCO Finland
Extensive CT of head and brain
3.1
8.9
47
155
PJ4AT
NOMESCO Finland
Labeling lymphnode with ultrasound guidance
24.2
8.9
12
5
YA1CD
NOMESCO Finland
Very extensive CT examination of head and neck for dose design of radiotherapy
24.2
8.9
12
5
A02BC01
ATC
omeprazole; systemic
1.5
8.8
357
2609
AA1CD
NOMESCO Finland
Very extensive CT of head and brain
3.7
8.8
36
98
D48.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other specified sites
6.6
8.7
21
32
D48.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Neoplasm of uncertain or unknown behaviour, unspecified
3.9
8.7
34
89
ZXX04
NOMESCO Finland
Extent of procedure, 4 units
11.7
8.6
15
13
R06AE07
ATC
cetirizine; oral
1.4
8.5
494
3876
C83
ICD-10 Finland
Non-follicular lymphoma
90.6
8.4
9
*
C83.33
ICD-10 Finland
Primary medical lymphoma with large B cells
+∞
8.3
8
*
9695/3-C77.2
ICD-O-3
Follicular lymphoma, grade 1 of intra-abdominal lymph nodes
+∞
8.3
8
*
9591/3-C77.3
ICD-O-3
Malignant lymphoma, non-Hodgkin, NOS, of lymph nodes of axilla or arm
+∞
8.3
8
*
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.0
8.3
113
603
D64.9
ICD-10 Finland
Anaemia, unspecified
1.8
8.3
141
818
YX9AD
NOMESCO Finland
Other CT eamination for dose design of radiotherapy
3.0
8.2
44
148
WW200
NOMESCO Finland
Immunization
2.9
8.1
47
165
N03AX16
ATC
pregabalin; oral
1.5
8.0
293
2088
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
2.0
8.0
96
490
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
4.4
8.0
27
62
WB401
NOMESCO Finland
Simple antibody therapy of primary tumour
4.8
8.0
25
53
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.5
7.9
376
2829
D48.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Connective and other soft tissue
4.1
7.9
29
72
YL1AD
NOMESCO Finland
CT examination of pelvis for dose design of radiotherapy
3.9
7.8
30
78
TNE20
NOMESCO Finland
Bone marrow aspiration, pelvis
15.1
7.7
12
8
ZXF99
NOMESCO Finland
Other r3eason to interrupt procedure
8.9
7.5
15
17
GEA00
NOMESCO Finland
Mediastinoscopy
8.9
7.5
15
17
KBV02
NOMESCO Finland
Cystoscopic insertion of stent into ureter
3.3
7.5
36
112
QAA05
NOMESCO Finland
Incision for biopsy of skin of head or neck
2.9
7.3
42
147
9691/3-C77.2
ICD-O-3
Follicular lymphoma, grade 2 of intra-abdominal lymph nodes
+∞
7.3
7
*
9652/3-C77.9
ICD-O-3
Hodgkin lymphoma, mixed cellularity, NOS, of lymph node, NOS
+∞
7.3
7
*
PJ002
NOMESCO Finland
Radical radiotherapy of neck, clavicle and axilla
+∞
7.3
7
*
D11.70
ICD-10 Finland
Gland sublingual
9.4
7.3
14
15
B01AB10
ATC
tinzaparin; parenteral
1.9
7.2
97
520
CFA20
NOMESCO Finland
Biopsy of conjunctiva
30.2
7.2
9
*
WE100
NOMESCO Finland
Profylactic cytostatic therapy
30.2
7.2
9
*
OAB73
NOMESCO Finland
Prevention and treatment of malnutrition
6.6
7.1
17
26
D80.9
ICD-10 Finland
Immunodeficiency with predominantly antibody defects, unspecified
12.1
7.1
12
10
J01DB01
ATC
cefalexin; oral
1.4
7.1
1014
9207
QX4AT
NOMESCO Finland
Ultrsound guided needle biopsy of skin
7.0
7.0
16
23
D37.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Digestive organ, unspecified
6.4
6.9
17
27
YG1BD
NOMESCO Finland
Extensive CT examination of thorax for dose design of radiotherapy
2.4
6.9
53
222
ELB30
NOMESCO Finland
Excision of submandibular gland
5.9
6.9
18
31
9699/3-C77.9
ICD-O-3
Marginal zone B-cell lymphoma, NOS, of lymph node, NOS
40.3
6.8
8
*
9680/3-C80.9
ICD-O-3
Diffuse large B-cell lymphoma, NOS, of unknown primary site
40.3
6.8
8
*
C85.0
ICD-10 Finland
Lymphosarcoma
40.3
6.8
8
*
A79
ICPC
Malignancy NOS
3.6
6.7
28
79
J01CA04
ATC
amoxicillin; systemic
1.4
6.6
952
8579
OAA41
NOMESCO Finland
Health check based on individual needs
12.3
6.6
11
9
BA3AT
NOMESCO Finland
Cytology of thyroid with ultrasound quidance
3.3
6.6
30
91
EMA10
NOMESCO Finland
Biopsy of tonsil
10.1
6.5
12
12
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.6
6.5
149
946
D37.2
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Small intestine
6.2
6.5
16
26
EP1DG
NOMESCO Finland
Very extensive examination of soft tissue of neck with high intesity magnet
5.4
6.5
18
34
R19.0
ICD-10 Finland
Intra-abdominal and pelvic swelling, mass and lump
2.8
6.4
38
137
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
1.9
6.4
90
488
J02AC03
ATC
voriconazole; systemic
14.4
6.4
10
7
7856A
ICD-9 Finland
Symptoms involving cardiovascular system, Enlargement of lymph nodes
14.4
6.4
10
7
C91.1
ICD-10 Finland
Chronic lymphocytic leukaemia of B-cell type
3.8
6.4
25
67
ED1AA
NOMESCO Finland
Mandipular X-ray examination
6.6
6.3
15
23
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
2.7
6.3
41
157
OAB38
NOMESCO Finland
Psychosocial guidance and counselling
18.1
6.3
9
5
9698/3-C77.4
ICD-O-3
Follicular lymphoma, grade 3 of lymph nodes of inguinal region or leg
+∞
6.3
6
*
9691/3-C17.9
ICD-O-3
Follicular lymphoma, grade 2 of small intestine, NOS
+∞
6.3
6
*
9691/3-C09.9
ICD-O-3
Follicular lymphoma, grade 2 of tonsil, NOS
+∞
6.3
6
*
9690/3-C77.3
ICD-O-3
Follicular lymphoma, NOS, of lymph nodes of axilla or arm
+∞
6.3
6
*
C83.6
ICD-10 Finland
Undifferentiated (diffuse) non-Hodgkin's lymphoma
+∞
6.3
6
*
H02AB09
ATC
hydrocortisone; systemic
3.1
6.3
32
106
J02AC01
ATC
fluconazole; systemic
1.4
6.2
413
3279
WW402
NOMESCO Finland
Leucoferesis
12.6
6.1
10
8
C92.1
ICD-10 Finland
Chronic myeloid leukaemia [CML], BCR/ABL-positive
8.6
6.1
12
14
D48.3
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Retroperitoneum
10.1
6.0
11
11

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: CD2_FOLLICULAR_LYMPHOMA – Follicular lymphoma, hilmo

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).