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This is a non-core endpoint: only basic statistics are computed.

See its core counterpart CD2_TNK_LYMPHOMA_EXALLC for full statistics.

Mature T/NK-cell lymphomas, hilmo

CD2_TNK_LYMPHOMA

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 C84
  • Cause of death: ICD-10 C84

2 out of 7 registries used, show all original rules.

458

4. Check minimum number of events

None

458

5. Include endpoints

None

458

6. Filter based on genotype QC (FinnGen only)

458

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF12
Parent code in ICD-10
C81-C96
Name in latin
Lymphomata T-cellularia peripherica et cutanea

Similar endpoints

List of similar endpoints to Mature T/NK-cell lymphomas, hilmo based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Similar with more cases:

Venn diagram with a set fully inside an highlighted set Similar with less cases:

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 458 166 292
Unadjusted period prevalence (%) 0.10 0.06 0.13
Median age at first event (years) 65.19 64.58 65.53

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
415
Matched controls
4150
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
C84.0
ICD-10 Finland
Mycosis fungoides
+∞
218.7
190
*
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
38.5
145.5
189
88
C84.59
ICD-10 Finland
Other and unspecified T-cell lymphomas
+∞
120.9
110
*
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
10.8
76.2
165
238
C84.49
ICD-10 Finland
Peripheral T-cell lymphoma, unspecified cell type
+∞
74.2
69
*
9700/3-C44.9
ICD-O-3
Mycosis fungoides of skin, NOS
+∞
73.1
68
*
C84.51
ICD-10 Finland
Other and unspecified T-cell lymphomas
+∞
68.7
64
*
XW000
NOMESCO Finland
Bone marrow biopsy
15.9
59.1
100
81
L03AA02
ATC
filgrastim; parenteral
22.6
59.0
87
48
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
15.9
54.0
91
72
JN4BD
NOMESCO Finland
Extensive body CT
6.6
46.9
138
290
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
9.9
45.0
96
122
L30.9
ICD-10 Finland
Dermatitis, unspecified
5.2
41.9
158
440
C84.4
ICD-10 Finland
Peripheral T-cell lymphoma, not elsewhere classified
+∞
41.3
39
*
D07AB08
ATC
desonide; topical
6.8
40.6
114
220
L03AA13
ATC
pegfilgrastim; parenteral
15.8
39.7
66
49
WW500
NOMESCO Finland
Blood transfusion
10.9
38.6
77
85
C84.5
ICD-10 Finland
Other mature T/NK-cell lymphomas
+∞
38.1
36
*
R59.1
ICD-10 Finland
Generalized enlarged lymph nodes
35.1
36.6
47
15
R59.0
ICD-10 Finland
Localized enlarged lymph nodes
17.5
36.5
58
38
PJA10
NOMESCO Finland
Exploration of lymph nodes
32.9
36.0
47
16
C84.41
ICD-10 Finland
Peripheral T-cell lymphoma, medium-sized cell type
+∞
36.0
34
*
C85.9
ICD-10 Finland
Non-Hodgkin lymphoma, unspecified
80.8
33.4
37
5
C84.43
ICD-10 Finland
Peripheral T-cell lymphoma, large cell type
+∞
32.7
31
*
E0000UV
ATC
NA
3.6
32.5
227
1052
H02AB06
ATC
prednisolone; systemic
3.5
31.7
269
1436
JN6BD
NOMESCO Finland
Extensive CT of torso and neck
56.1
30.9
36
7
A49.9
ICD-10 Finland
Bacterial infection, unspecified
5.2
30.8
108
265
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
12.8
30.4
55
49
D07AD01
ATC
clobetasol; topical
4.5
29.8
122
351
A03FA01
ATC
metoclopramide; systemic, rectal
4.0
29.1
142
480
C83.34
ICD-10 Finland
Anaplastic large cell lymphoma
+∞
28.5
27
*
R50.9
ICD-10 Finland
Fever, unspecified
4.4
27.6
116
339
WW300
NOMESCO Finland
Transfer of autologic stem cells
103.7
27.0
29
*
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
6.8
26.8
71
122
PJD41
NOMESCO Finland
Excision of cervical lymph nodes
25.3
26.6
37
16
WXQ27
NOMESCO Finland
UVB narrow spectrum light therapy
25.3
26.6
37
16
L26
ICD-10 Finland
Exfoliative dermatitis
55.6
26.6
31
6
D07AC01
ATC
betamethasone; topical
3.2
26.4
206
984
EP1AE
NOMESCO Finland
Neck ultrasound examination
7.2
25.7
65
104
D70.82
ICD-10 Finland
Drug-induced neutropenia
27.2
25.7
35
14
WW409
NOMESCO Finland
Other aferesis
265.3
24.9
25
*
D07AC13
ATC
mometasone; topical
3.3
24.8
167
712
9700/3-C44.5
ICD-O-3
Mycosis fungoides of skin of trunk
+∞
24.2
23
*
C84.1
ICD-10 Finland
Sézary disease
+∞
24.2
23
*
D05BB02
ATC
acitretin; oral
11.1
22.9
44
44
Z94.8
ICD-10 Finland
Other transplanted organ and tissue status
55.3
22.3
26
5
WXQ12
NOMESCO Finland
Psoralen - Ultraviolet A therapy with local sensitivisation
66.3
22.1
25
*
PJD45
NOMESCO Finland
Excision of inguinal lymph nodes
41.1
22.0
27
7
E000001
ATC
NA
3.4
21.9
128
482
WXQ10
NOMESCO Finland
Psoralen - Ultraviolet A therapy with systemic sensitivisation
+∞
21.0
20
*
M04AA01
ATC
allopurinol; systemic
3.5
20.9
113
400
JN4AD
NOMESCO Finland
Body CT examination
4.7
20.6
75
186
Z51.1
ICD-10 Finland
Chemotherapy session for neoplasm
16.6
19.6
31
20
PJ2AE
NOMESCO Finland
Lymphnode ultrasound examination
27.6
19.4
26
10
9705/3-C77.9
ICD-O-3
Angioimmunoblastic T-cell lymphoma of lymph node, NOS
+∞
18.9
18
*
A04AA02
ATC
granisetron; systemic, transdermal
5.8
18.8
55
106
127
Kela drug reimbursment
Transplant complication
14.6
18.1
30
22
JN6AD
NOMESCO Finland
CT of torso and neck
21.2
18.0
26
13
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
7.0
17.9
45
71
9702/3-C77.9
ICD-O-3
Mature T-cell lymphoma, NOS, of lymph node, NOS
+∞
17.8
17
*
1XX25
NOMESCO Finland
NA
+∞
17.8
17
*
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
6.0
17.8
50
92
134
Kela drug reimbursment
General erythroderma
26.9
17.1
23
9
C10AB05
ATC
fenofibrate; oral
9.4
16.5
34
39
WD115
NOMESCO Finland
Multiple cystostatic therapy of methastized malignancy
12.4
16.3
29
25
A04AA01
ATC
ondansetron; systemic, rectal
4.8
16.1
55
127
L01AA02
ATC
chlorambucil; oral
39.7
15.5
19
5
J05AB11
ATC
valaciclovir; oral
3.4
15.5
83
284
H02AB07
ATC
prednisone; oral
3.1
14.9
90
336
WD135
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
19.3
14.8
22
12
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.3
14.8
222
1387
E000002
ATC
NA
3.6
14.7
72
231
TQW80
NOMESCO Finland
Local dermatologic skincare
7.6
14.6
34
48
D02AE01
ATC
carbamide; topical
4.3
14.5
56
146
JN5DR
NOMESCO Finland
PET-CT of upper body metabolism
11.5
14.2
26
24
ZX120
NOMESCO Finland
Intravenous
3.5
13.8
69
225
ZX196
NOMESCO Finland
NA
+∞
13.6
13
*
PJ2AT
NOMESCO Finland
Biopsy of lymphnode with ultrasound guidance
35.3
13.6
17
5
C83.9
ICD-10 Finland
Non-follicular (diffuse) lymphoma, unspecified
41.5
13.2
16
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.0
12.9
81
311
H02AB09
ATC
hydrocortisone; systemic
7.7
12.7
29
40
9702/3-C77.8
ICD-O-3
Mature T-cell lymphoma, NOS, of lymph nodes of multiple regions
+∞
12.6
12
*
9700/3-C44.7
ICD-O-3
Mycosis fungoides of skin of lower limb and hip
+∞
12.6
12
*
L41.9
ICD-10 Finland
Parapsoriasis, unspecified
133.9
12.5
13
*
WD415
NOMESCO Finland
Demanding antibody therapy of methastized malignancy
9.7
12.2
24
26
TPX10
NOMESCO Finland
Implantation of vascular injection port
6.8
12.1
30
47
E000006
ATC
NA
4.0
12.1
49
134
D07AB02
ATC
hydrocortisone butyrate; topical
2.3
11.9
137
736
E000003
ATC
NA
5.1
11.8
37
78
A02BC02
ATC
pantoprazole; systemic
2.1
11.8
281
2059
R59.9
ICD-10 Finland
Enlarged lymph nodes, unspecified
19.6
11.7
17
9
WW402
NOMESCO Finland
Leucoferesis
123.3
11.5
12
*
XQ848
NOMESCO Finland
Dermatological photography
7.6
11.4
26
36
L03AA14
ATC
lipegfilgrastim; parenteral
10.0
11.4
22
23
D07AA02
ATC
hydrocortisone; topical
2.9
11.1
74
293
J02AC01
ATC
fluconazole; systemic
2.2
11.1
150
861
PJD42
NOMESCO Finland
Excision of axillary lymph nodes
12.4
10.9
19
16
QBA99
NOMESCO Finland
Other local destruction of skin of trunk
18.4
10.8
16
9
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
5.4
10.5
31
61
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
5.8
10.5
29
53
YNB10
NOMESCO Finland
Collection of stem cells for transplant
112.8
10.5
11
*
L41.8
ICD-10 Finland
Other parapsoriasis
112.8
10.5
11
*
D02AX
ATC
Other emollients and protectives
6.2
10.3
27
46
R21
ICD-10 Finland
Rash and other nonspecific skin eruption
4.7
10.2
34
77
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.4
10.1
95
456
L20.0
ICD-10 Finland
Besnier prurigo
4.7
10.1
34
78
L04AD01
ATC
ciclosporin; systemic
7.0
10.1
24
36
J01MA12
ATC
levofloxacin; systemic
2.3
10.0
105
533
WZC30
NOMESCO Finland
Teaching
2.7
9.8
73
307
A41.9
ICD-10 Finland
Sepsis, unspecified
4.9
9.7
31
67
D07BA04
ATC
hydrocortisone and antiseptics; topical
3.1
9.7
54
190
C83.31
ICD-10 Finland
Diffuse lymphoma with large B cells
9.4
9.6
19
21
A07AA02
ATC
nystatin; oral
3.6
9.6
43
129
T86.0
ICD-10 Finland
Bone-marrow transplant rejection
102.3
9.5
10
*
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
5.3
9.4
28
56
Z52.89
ICD-10 Finland
Donor of other organ or tissue
+∞
9.4
9
*
L41.4
ICD-10 Finland
Large plaque parapsoriasis
+∞
9.4
9
*
Z51.5
ICD-10 Finland
Palliative care
3.4
9.0
44
141
N02AA05
ATC
oxycodone; systemic
2.4
8.9
85
407
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
2.2
8.9
105
558
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
5.9
8.9
24
43
A05AA02
ATC
ursodeoxycholic acid; oral
9.8
8.9
17
18
TGC00
NOMESCO Finland
Bronchial lavation
5.5
8.8
25
48
XX9CD
NOMESCO Finland
Very extensive complementary CT
51.1
8.7
10
*
C81.9
ICD-10 Finland
Hodgkin lymphoma, unspecified
51.1
8.7
10
*
C82.9
ICD-10 Finland
Follicular lymphoma, unspecified
51.1
8.7
10
*
I88.9
ICD-10 Finland
Nonspecific lymphadenitis, unspecified
51.1
8.7
10
*
B72
ICPC
Hodgkin Lymphoma
51.1
8.7
10
*
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.6
8.7
64
269
C92.0
ICD-10 Finland
Acute myeloblastic leukaemia [AML]
28.2
8.5
11
*
XW4XT
NOMESCO Finland
Biopsy of other inner organ with radiological guidance guidance
28.2
8.5
11
*
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.0
8.4
144
885
WW306
NOMESCO Finland
Transfer of stem cells from foreign registered donator
+∞
8.4
8
*
C83.35
ICD-10 Finland
T-cell-rich B-cell lymphoma
+∞
8.4
8
*
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
2.9
8.2
51
193
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
2.6
8.2
61
258
L04AA06
ATC
mycophenolic acid; systemic
7.1
8.2
19
28
D69.5
ICD-10 Finland
Secondary thrombocytopenia
34.1
8.1
10
*
H26.3
ICD-10 Finland
Drug-induced cataract
22.5
8.1
11
5
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
3.5
8.0
36
109
ZX112
NOMESCO Finland
Subcutaneous
6.8
8.0
19
29
D69.6
ICD-10 Finland
Thrombocytopenia, unspecified
6.3
7.9
20
33
ZXE00
NOMESCO Finland
One hour or less
1.8
7.6
169
1136
C85.7
ICD-10 Finland
Other specified types of non-Hodgkin lymphoma
81.5
7.4
8
*
TPH04
NOMESCO Finland
Cathetrisation of vein
2.0
7.4
99
552
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.9
7.4
120
719
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
7.0
7.4
17
25
TK800
NOMESCO Finland
Hemodialysis
5.3
7.3
21
41
9700/3-C44.6
ICD-O-3
Mycosis fungoides of skin of upper limb and shoulder
+∞
7.3
7
*
C84.42
ICD-10 Finland
Peripheral T-cell lymphoma, both medium and large cell type
+∞
7.3
7
*
C84.2
ICD-10 Finland
T-zone lymphoma
+∞
7.3
7
*
9717/3-C17.9
ICD-O-3
Intestinal T-cell lymphoma of small intestine, NOS
+∞
7.3
7
*
C83.52
ICD-10 Finland
T-lymphoblastic lymphoma or leukemia
+∞
7.3
7
*
C84
ICD-10 Finland
Mature T/NK-cell lymphomas
+∞
7.3
7
*
C84.3
ICD-10 Finland
Lymphoepithelioid lymphoma
+∞
7.3
7
*
H03AA01
ATC
levothyroxine sodium; systemic
2.1
7.3
96
530
D07BB04
ATC
hydrocortisone butyrate and antiseptics; topical
2.4
7.2
64
297
H02AB02
ATC
dexamethasone; systemic
2.6
7.2
53
223
C83.3
ICD-10 Finland
Diffuse large B-cell lymphoma
30.6
7.2
9
*
L30.3
ICD-10 Finland
Infective dermatitis
4.6
7.1
23
52
L98.9
ICD-10 Finland
Disorder of skin and subcutaneous tissue, unspecified
7.2
7.1
16
23
L40.0
ICD-10 Finland
Psoriasis vulgaris
3.7
7.0
29
82
WD405
NOMESCO Finland
Simple antiboidy therapy of methastized malignancy
6.0
7.0
18
31
ZX108
NOMESCO Finland
Inhalation
11.2
6.8
12
11
E000007
ATC
NA
3.3
6.8
32
101
RS340
NOMESCO Finland
NA
40.7
6.8
8
*
J02AC03
ATC
voriconazole; systemic
40.7
6.8
8
*
B25.9
ICD-10 Finland
Cytomegaloviral disease, unspecified
40.7
6.8
8
*
JN6DR
NOMESCO Finland
PET-CT of whole body metabolism
17.0
6.8
10
6
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.8
6.7
42
158
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.9
6.7
102
596
JFB00
NOMESCO Finland
Partial resection of small intestine
6.1
6.7
17
29
317
Kela drug reimbursment
Topical pimecrolimus and tacrolimus
12.5
6.6
11
9
D64.9
ICD-10 Finland
Anaemia, unspecified
2.4
6.6
57
261
D72.8
ICD-10 Finland
Other specified disorders of white blood cells
10.3
6.6
12
12
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
3.0
6.6
37
131
9591/3-C77.9
ICD-O-3
Malignant lymphoma, non-Hodgkin, NOS, of lymph node, NOS
70.9
6.4
7
*
GEA00
NOMESCO Finland
Mediastinoscopy
70.9
6.4
7
*
JN4ED
NOMESCO Finland
Body CT examination with specail preparation
70.9
6.4
7
*
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
3.1
6.4
33
112
TNE25
NOMESCO Finland
Drill biopsy of bone marrow, pelvis
6.7
6.4
15
23
PH1AE
NOMESCO Finland
Ultrasound examination of upper extremity veins
6.7
6.4
15
23
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
2.8
6.4
38
142
FM1FN
NOMESCO Finland
Heart function isotope examination
18.4
6.3
9
5
9705/3-C77.8
ICD-O-3
Angioimmunoblastic T-cell lymphoma of lymph nodes of multiple regions
+∞
6.3
6
*
D76.1
ICD-10 Finland
Haemophagocytic lymphohistiocytosis
+∞
6.3
6
*
WW302
NOMESCO Finland
Allogenic transfer of stem cells from relative
+∞
6.3
6
*
9701/3-C44.9
ICD-O-3
Sezary syndrome of skin, NOS
+∞
6.3
6
*
9702/3-C80.9
ICD-O-3
Mature T-cell lymphoma, NOS, of unknown primary site
+∞
6.3
6
*
9702/3-C42.1
ICD-O-3
Mature T-cell lymphoma, NOS, of bone marrow
+∞
6.3
6
*
B25.8
ICD-10 Finland
Other cytomegaloviral diseases
27.1
6.2
8
*
S18
ICPC
Laceration/cut
1.7
6.1
182
1312
D07XC01
ATC
betamethasone, combinations; topical
2.2
6.1
61
298
J01DB01
ATC
cefalexin; oral
1.8
6.1
322
2735

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: CD2_TNK_LYMPHOMA – Mature T/NK-cell lymphomas, hilmo

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).