obsolete_sarcoidosis: ['An idiopathic inflammatory disorder characterized by the formation of non-necrotizing epithelioid granulomas which contain giant cells. It usually affects the lungs, lymph nodes, liver, and skin.', 'An idiopathic systemic inflammatory granulomatous disorder comprised of epithelioid and multinucleated giant cells with little necrosis. It usually invades the lungs with fibrosis and may also involve lymph nodes, skin, liver, spleen, eyes, phalangeal bones, and parotid glands.']
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
3 out of 7 registries used, show all original rules. |
5554 |
4. Check minimum number of eventsNone |
5554 |
5. Include endpointsNone |
5554 |
6. Filter based on genotype QC (FinnGen only) |
5554 |
Control definitions (FinnGen only)
- Control exclude
- D3_IMMUNEMECHANISM
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- D80-D89
- Name in latin
- Sarcoidosis
Similar endpoints
↥List of similar endpoints to
Sarcoidosis
based on the number of shared cases.
Similar with more cases:
- Certain disorders involving the immune mechanism
- Diagnoses used for exclusion with ILD
- Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
- Excluding asthma or asthma-COPD overlap
- COPD differential diagnosis
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 34942 | 18933 | 15788 |
| Only index persons | 30759 | 16617 | 14142 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.49 | 0.54 | 0.44 |
| Only index persons | 0.58 | 0.61 | 0.54 |
| Median age at first event (years) | |||
| Whole population | 46.39 | 49.71 | 42.37 |
| Only index persons | 45.23 | 48.24 | 41.69 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 5554 | 3113 | 2441 |
| Unadjusted period prevalence (%) | 1.07 | 1.06 | 1.08 |
| Median age at first event (years) | 46.75 | 48.25 | 44.84 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 5000
- Matched controls
- 49999
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H02AB06
ATC
prednisolone; systemic
3.6
323.0
3213
16696
UGC12
NOMESCO Finland
Flexible bronchoscopy
7.5
323.0
1015
1647
D86.3
ICD-10 Finland
Sarcoidosis of skin
3457.9
323.0
334
*
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
8.1
323.0
1378
2231
1350A
ICD-9 Finland
Sarcoidosis[SARCOIDOSIS]
+∞
323.0
426
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.4
323.0
2991
15103
D86.0
ICD-10 Finland
Sarcoidosis of lung
14511.8
323.0
1870
*
13599
ICD-8 Finland
Sarcoidosis, Unspecified
+∞
323.0
457
*
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
9.7
323.0
828
1000
132
Kela drug reimbursment
Sarcoidosis
+∞
323.0
897
*
D86.8
ICD-10 Finland
Sarcoidosis of other and combined sites
+∞
323.0
1047
*
D86.1
ICD-10 Finland
Sarcoidosis of lymph nodes
+∞
323.0
833
*
I41.8*D86.8
ICD-10 Finland
Sarcoid myocarditis
3253.8
323.0
316
*
13597
ICD-8 Finland
Sarcoidosis, Suspecta
+∞
323.0
524
*
D86.2
ICD-10 Finland
Sarcoidosis of lung with sarcoidosis of lymph nodes
+∞
323.0
1270
*
TGC00
NOMESCO Finland
Bronchial lavation
14.7
323.0
574
437
D86.9
ICD-10 Finland
Sarcoidosis, unspecified
14239.8
323.0
1122
*
GEA00
NOMESCO Finland
Mediastinoscopy
72.3
239.0
274
40
R59.0
ICD-10 Finland
Localized enlarged lymph nodes
9.9
228.4
483
535
D86
ICD-10 Finland
Sarcoidosis
768.7
225.9
221
*
XG410
NOMESCO Finland
Flow-volume spirometry
7.0
201.7
535
846
XGX32
NOMESCO Finland
Bronchoscopic ultrasonography
28.0
193.2
268
101
I41.8
ICD-10 Finland
Myocarditis in other diseases classified elsewhere
937.2
185.6
181
*
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
4.7
151.9
558
1292
XG470
NOMESCO Finland
Measurement of diffusion capastity of the lungs
7.6
151.7
373
522
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
7.0
140.7
366
555
FJA10
NOMESCO Finland
Transvenous biopsy of right ventricle
33.1
137.3
182
57
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
3.7
134.8
648
1918
GEA20
NOMESCO Finland
Mediastinoscopy with excision of lesion
82.0
134.1
151
19
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
4.3
115.7
459
1136
M14.8*D86.8
ICD-10 Finland
Arthropathy in sarcoidosis
+∞
108.7
104
*
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
2.2
103.0
1247
6463
FPG32
NOMESCO Finland
Implantation of cardioverter-defibrillator with atrial and ventricular electrodes
16.7
101.1
165
102
A02BC02
ATC
pantoprazole; systemic
1.9
95.4
3328
25649
FM1DG
NOMESCO Finland
Very extensive MRI examination of heart with high intesity magnet
10.2
94.3
192
194
N16.2*D86.8
ICD-10 Finland
Renal tubulo-interstitial disorders in sarcoidosis
+∞
94.0
90
*
R59.1
ICD-10 Finland
Generalized enlarged lymph nodes
9.5
92.8
197
215
R03AC02
ATC
salbutamol; inhalant
1.8
92.5
2695
19416
XFP20
NOMESCO Finland
Check up of cardiac pacemaker
3.6
92.2
455
1357
M05BA04
ATC
alendronic acid; oral
3.1
90.9
554
1935
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.3
90.2
957
4617
L04AX01
ATC
azathioprine; systemic
4.1
89.3
377
983
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.9
89.2
1715
10635
FM1JR
NOMESCO Finland
Heart, extensive metabolic PET with CT
46.4
88.7
109
24
TGE00
NOMESCO Finland
Needle biopsy of mediastinum
30.9
87.9
118
39
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
3.3
85.8
463
1479
GCA98
NOMESCO Finland
Other bronchoscopic procedure on bronchus
16.7
84.7
138
85
H22.1*D86.8
ICD-10 Finland
Iridocyclitis in sarcoidosis
790.6
79.6
78
*
R06.0
ICD-10 Finland
Dyspnoea
2.0
76.9
1286
7483
I44.2
ICD-10 Finland
Atrioventricular block, complete
5.8
75.2
223
399
J45.9
ICD-10 Finland
Asthma, unspecified
2.1
74.6
969
5078
TGD00
NOMESCO Finland
Needle biopsy of lung
18.1
68.6
108
61
GD1AD
NOMESCO Finland
Thorax CT examination
3.7
68.1
318
901
H20.1
ICD-10 Finland
Chronic iridocyclitis
8.8
65.1
143
166
Z95.0
ICD-10 Finland
Presence of electronic cardiac devices
3.5
64.3
318
944
R03BA02
ATC
budesonide; inhalant
2.0
64.0
940
5146
H04.10
ICD-10 Finland
Dry eye syndrome
2.5
63.5
570
2489
R05
ICD-10 Finland
Cough
2.0
62.3
1009
5726
L52
ICD-10 Finland
Erythema nodosum
12.8
62.0
112
89
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
2.4
61.4
554
2422
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
3.6
61.2
297
868
Z45.0
ICD-10 Finland
Adjustment and management of cardiac devices
3.8
60.2
271
744
Z01.8
ICD-10 Finland
Other specified special examinations
1.9
59.5
1105
6580
G53.2*D86.8
ICD-10 Finland
Multiple cranial nerve palsies in sarcoidosis
+∞
55.3
53
*
TFJ02
NOMESCO Finland
Muscle biopsy of heart
27.2
54.3
75
28
C03CA01
ATC
furosemide; systemic
1.8
53.8
1258
8038
R50.9
ICD-10 Finland
Fever, unspecified
2.0
52.2
709
3729
C07AB07
ATC
bisoprolol; oral
1.6
49.4
2176
16438
R59.9
ICD-10 Finland
Enlarged lymph nodes, unspecified
8.6
47.7
106
126
TPJ00
NOMESCO Finland
Biopsy of superficial lymph node
37.3
46.3
59
16
J45.1
ICD-10 Finland
Nonallergic asthma
2.5
45.8
389
1640
TAB00
NOMESCO Finland
Lumbar puncture
3.0
45.2
283
994
H02AB07
ATC
prednisone; oral
1.9
44.3
733
4141
H30.2
ICD-10 Finland
Posterior cyclitis
22.8
43.5
63
28
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.8
43.5
844
5033
1440
FHL
Mediastinoscopy
147.9
41.8
44
*
1240
FHL
Bronchoscopy
8.4
41.6
93
112
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
2.1
41.2
506
2540
WX892
NOMESCO Finland
Monitored bed care
2.3
41.0
410
1874
GDA98
NOMESCO Finland
Other bronchoscopic incision, excision of lesion or repair of lung
10.0
41.0
83
84
TGD04
NOMESCO Finland
Needle biopsy of the lungs in bronchoscopy
12.1
40.7
75
63
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.5
40.6
1871
14075
H02AB04
ATC
methylprednisolone; systemic
1.8
40.3
729
4237
R03BA08
ATC
ciclesonide; inhalant
2.2
40.2
454
2195
G47.3
ICD-10 Finland
Sleep apnoea
1.7
39.8
1049
6850
AP4
HP
Myocardial biopsy
24.6
39.7
56
23
N16.2
ICD-10 Finland
Renal tubulo-interstitial disorders in blood diseases and disorders involving the immune mechanism
+∞
39.6
38
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.6
38.9
1337
9356
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.2
37.8
415
1981
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.7
36.6
892
5679
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.6
36.2
992
6522
R03BA01
ATC
beclometasone; inhalant
1.8
36.1
685
4035
M14.8
ICD-10 Finland
Arthropathies in other specified diseases classified elsewhere
186.3
35.8
37
*
FPE20
NOMESCO Finland
Implantation of transvenous cardiac pacemaker with atrial and ventricular electrodes
3.0
35.4
214
733
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.1
35.2
455
2326
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.8
35.2
622
3573
J84.9
ICD-10 Finland
Interstitial pulmonary disease, unspecified
4.5
34.6
126
285
WX408
NOMESCO Finland
General anesthesy, balanced
1.6
34.4
1253
8843
I44.1
ICD-10 Finland
Atrioventricular block, second degree
4.4
33.5
125
290
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.6
33.3
1006
6766
I47.2
ICD-10 Finland
Ventricular tachycardia
3.8
32.8
142
378
J45.0
ICD-10 Finland
Predominantly allergic asthma
2.1
32.1
401
2019
PJD41
NOMESCO Finland
Excision of cervical lymph nodes
5.1
31.6
102
204
J01MA12
ATC
levofloxacin; systemic
1.6
31.2
838
5456
JN4BD
NOMESCO Finland
Extensive body CT
1.9
31.0
527
2983
P01BA02
ATC
hydroxychloroquine; oral
2.0
30.4
407
2107
L04AA06
ATC
mycophenolic acid; systemic
4.0
29.9
122
309
J01FA06
ATC
roxithromycin; oral
1.4
29.7
1840
14443
FM1CG
NOMESCO Finland
Extensive examination of hear with high intensity magnet
10.5
29.6
58
56
N02BE01
ATC
paracetamol; systemic, rectal
1.5
29.5
4065
37061
R03AK08
ATC
formoterol and beclometasone; inhalant
2.7
28.9
208
797
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
2.4
28.9
260
1127
D38.3
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Mediastinum
10.3
28.8
57
56
XF404
NOMESCO Finland
Ambulatory ECG
1.9
28.4
443
2429
GDA11
NOMESCO Finland
Thoracoscopic biopsy of lung
13.4
28.1
49
37
XG474
NOMESCO Finland
Exhalation nntrogen oxide
3.0
28.1
167
566
51925
ICD-8 Finland
Other diseases of respiratory system, Infiltratio pulmonis NUD
15.5
28.1
46
30
E83.50
ICD-10 Finland
Hypercalcemia
5.0
27.8
91
185
WZC30
NOMESCO Finland
Teaching
1.7
27.7
615
3783
UJF32
NOMESCO Finland
Coloscopy
1.5
27.5
1135
8174
R03AK07
ATC
formoterol and budesonide; inhalant
1.6
27.2
868
5884
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
2.5
27.1
225
936
H02AB09
ATC
hydrocortisone; systemic
3.5
26.8
129
376
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
2.7
26.7
189
719
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.7
26.6
663
4209
J01AA02
ATC
doxycycline; systemic
1.4
26.5
3677
33049
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
2.0
26.5
369
1939
PH1AC
NOMESCO Finland
Flebography of over extremity with X-ray
4.7
26.5
92
200
69520
ICD-8 Finland
Erythematous condition, Erythema nodosum
18.3
26.1
40
22
M25.5
ICD-10 Finland
Pain in joint
1.5
26.0
1259
9359
GD1LA
NOMESCO Finland
GD
4.5
25.4
92
209
I42.9
ICD-10 Finland
Cardiomyopathy, unspecified
3.7
25.2
113
312
TPH04
NOMESCO Finland
Cathetrisation of vein
1.5
25.1
906
6309
GE1BE
NOMESCO Finland
Mediastinal ultrasound examinaiton through oesophagus
17.1
24.8
39
23
GD5BD
NOMESCO Finland
Thorax and upper abdomen combined extensive CT examination of
3.3
24.8
128
395
ZX120
NOMESCO Finland
Intravenous
1.8
24.7
436
2490
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
1.9
24.5
405
2264
I50.9
ICD-10 Finland
Heart failure, unspecified
1.7
24.3
502
3014
FPE37
NOMESCO Finland
Implantation of biventricular cardioverter-defibrillator with atrial and ventricular electrodes
12.0
24.2
44
37
A10AC01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate-acting)
2.0
24.1
343
1816
UGC18
NOMESCO Finland
Flexible bronchoscopy with biopsy of lung
8.1
24.1
54
67
D80.1
ICD-10 Finland
Nonfamilial hypogammaglobulinaemia
+∞
24.0
23
*
K77.8*D86.8
ICD-10 Finland
Hepatic granulomas in sarcoidosis
+∞
24.0
23
*
103
Kela drug reimbursment
Diabetes, insulin-treated
1.5
23.9
1124
8277
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.5
23.7
1046
7605
KA3AT
NOMESCO Finland
Biopsy of kidney with ultrasound guidance
4.4
23.6
86
197
J84.1
ICD-10 Finland
Other interstitial pulmonary diseases with fibrosis
3.9
23.5
98
255
A02BC01
ATC
omeprazole; systemic
1.4
23.2
1198
8982
PJ2AE
NOMESCO Finland
Lymphnode ultrasound examination
5.7
23.2
67
119
XCW99
NOMESCO Finland
Other investigative procedure of eye
1.7
23.1
477
2863
1242
FHL
Bronchoscopy and transbronchial lung apia
230.9
22.6
23
*
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.4
22.5
1495
11727
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
2.0
22.3
310
1625
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.5
22.1
740
5051
R03AK06
ATC
salmeterol and fluticasone; inhalant
1.6
22.0
585
3770
M04AA01
ATC
allopurinol; systemic
1.7
21.9
515
3208
EP1AE
NOMESCO Finland
Neck ultrasound examination
2.1
21.8
261
1287
F1246
NOMESCO Finland
NA
17.1
21.7
34
20
I49.3
ICD-10 Finland
Ventricular premature depolarization
2.0
21.7
307
1619
J01DB01
ATC
cefalexin; oral
1.4
21.7
3811
34859
C03DA01
ATC
spironolactone; oral
1.7
21.2
454
2754
H26.3
ICD-10 Finland
Drug-induced cataract
6.1
21.0
57
94
A02BC03
ATC
lansoprazole; oral
1.4
20.9
1273
9809
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
1.5
20.7
880
6330
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.5
20.6
725
5003
XG405
NOMESCO Finland
Education on PEF monitoring
3.7
20.5
90
245
R03BA05
ATC
fluticasone; inhalant
1.5
20.5
756
5271
UDH02
NOMESCO Finland
Rhinopharyngoscopy
2.0
20.3
282
1477
ZX109
NOMESCO Finland
Instruction on medicine inhalation technique
4.9
20.3
66
135
M13.9
ICD-10 Finland
Arthritis, unspecified
1.9
20.3
323
1781
GD1CD
NOMESCO Finland
Thorax extensive CT-examination
4.8
20.2
67
140
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.3
20.2
1721
14010
PJA10
NOMESCO Finland
Exploration of lymph nodes
4.3
20.2
75
176
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
1.9
20.2
324
1792
C01BD01
ATC
amiodarone; systemic
2.7
20.1
141
536
XCK10
NOMESCO Finland
Photography of fundus of eye
1.7
20.0
425
2568
H03AA01
ATC
levothyroxine sodium; systemic
1.4
19.9
983
7275
D80.9
ICD-10 Finland
Immunodeficiency with predominantly antibody defects, unspecified
+∞
19.8
19
*
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
2.6
19.7
145
565
SPAT1262
SPAT
Handing over of treatment supplies
1.5
19.7
760
5346
JN4DR
NOMESCO Finland
Whole body metabolic PET with CT
14.6
19.3
32
22
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.3
19.2
2220
18877
201
Kela drug reimbursment
Chronic cardiac insufficiency
2.2
19.0
191
873
N18.8
ICD-10 Finland
Other chronic renal failure
2.8
19.0
125
457
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
1.8
18.9
325
1839
SPAT1263
SPAT
Sampling
1.3
18.8
1789
14768
JN5DR
NOMESCO Finland
PET-CT of upper body metabolism
3.5
18.8
87
249
R01AD09
ATC
mometasone; nasal
1.3
18.6
1928
16106
E66.01
ICD-10 Finland
Obesity due to excess calories
1.8
18.4
338
1954
R07.4
ICD-10 Finland
Chest pain, unspecified
1.4
18.4
1124
8635
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.6
18.3
469
2988
AS4
HP
Physiological pacemaker insertion DDD (R)
4.0
18.3
74
189
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
2.0
18.2
226
1134
D07AC01
ATC
betamethasone; topical
1.3
18.0
1456
11703
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
1.4
18.0
1387
11061
H22.1
ICD-10 Finland
Iridocyclitis in other diseases classified elsewhere
33.0
17.9
23
7
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.3
17.7
1371
10944
JN4JR
NOMESCO Finland
Whole body extensive metabolic PET with CT
5.1
17.6
55
108
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.5
17.5
712
5055
J01CA04
ATC
amoxicillin; systemic
1.3
17.5
3643
33433
J01FF01
ATC
clindamycin; systemic
1.4
17.4
1158
9008
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.3
17.4
1746
14475
FPG96
NOMESCO Finland
Other implantation of permanent cardioverter-defibrillator
7.6
17.3
40
53
I10
ICD-10 Finland
Essential (primary) hypertension
1.3
17.3
2466
21462
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
1.7
17.2
373
2270
R06.2
ICD-10 Finland
Wheezing
2.1
17.1
195
945
7931A
ICD-9 Finland
Nonspecific abnormal findings on radiological and other examination of body structure, Lung field
9.3
17.1
35
38
M81.4
ICD-10 Finland
Drug-induced osteoporosis
8.6
16.9
36
42
A02BC05
ATC
esomeprazole; systemic
1.3
16.8
1752
14587
A49.9
ICD-10 Finland
Bacterial infection, unspecified
1.6
16.8
416
2627
J06BA01
ATC
immunoglobulins, normal human, for extravascular adm.; systemic
+∞
16.7
16
*
120
Kela drug reimbursment
Hypogammaglobulinaemia
+∞
16.7
16
*
N02AX02
ATC
tramadol; systemic, rectal
1.3
16.6
1808
15142
1243
FHL
Bronchoscopy and other therapeutic procedure
27.6
16.5
22
8
JN4AD
NOMESCO Finland
Body CT examination
1.8
16.5
312
1823
R51.80
ICD-10 Finland
Headache
1.5
16.3
574
3945
I48
ICD-10 Finland
Atrial fibrillation and flutter
1.4
16.1
817
6049
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
1.6
16.1
471
3101
207
Kela drug reimbursment
Chronic arrhythmias
1.5
16.1
538
3655
J01MA14
ATC
moxifloxacin; systemic
1.7
16.1
366
2258
B01AA03
ATC
warfarin; systemic
1.4
16.0
721
5217
T90
ICPC
Diabetes non-insulin dependent
1.4
16.0
928
7045
R05
ICPC
Cough
1.4
15.7
873
6571
R5140
NOMESCO Finland
Monitoring the use of the aid
1.6
15.7
441
2874
I44.0
ICD-10 Finland
Atrioventricular block, first degree
3.8
15.7
67
180
F2680
NOMESCO Finland
NA
11.2
15.7
29
26
TPH07
NOMESCO Finland
Cathetrisation of artery
1.6
15.6
408
2612
J01FA10
ATC
azithromycin; systemic
1.3
15.3
2504
22030
G51.0
ICD-10 Finland
Bell palsy
2.4
15.3
125
519
S18
ICPC
Laceration/cut
1.3
15.3
1753
14737
I51.4
ICD-10 Finland
Myocarditis, unspecified
5.3
15.1
45
85
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
1.7
15.0
346
2141
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.3
15.0
1731
14548
J01FA09
ATC
clarithromycin; systemic
1.3
15.0
1343
10902
I42.0
ICD-10 Finland
Dilated cardiomyopathy
2.5
14.9
120
496
ZX110
NOMESCO Finland
Intracutaneous
12.4
14.8
26
21
XW000
NOMESCO Finland
Bone marrow biopsy
2.1
14.8
164
785
E0000UV
ATC
NA
1.3
14.8
1614
13459
J45.8
ICD-10 Finland
Mixed asthma
2.3
14.8
133
579
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
1.5
14.7
473
3184
XF400
NOMESCO Finland
ECG with 12 standard connections
1.5
14.7
633
4539
TGW99
NOMESCO Finland
Other minor procedure in thoracic surgery
10.4
14.7
28
27
D83.0
ICD-10 Finland
Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function
+∞
14.6
14
*
M63.3*D86.8
ICD-10 Finland
Myositis in sarcoidosis
+∞
14.6
14
*
CFA20
NOMESCO Finland
Biopsy of conjunctiva
11.9
14.5
26
22
WX110
NOMESCO Finland
Local anesthesy
1.3
14.5
3033
27425
CA1CG
NOMESCO Finland
Eye and orbita extensive MRI examination with high intensity magnet
5.1
14.5
45
89
AS8
HP
Physiological arrhythmia pacemaker insertionDDD (R) S
8.9
14.4
30
34
R03AC03
ATC
terbutaline; inhalant
1.5
14.4
579
4094
UJF30
NOMESCO Finland
Ileoscopy through colon
1.6
14.3
381
2454
R01AD12
ATC
fluticasone furoate; nasal
1.3
14.2
1199
9630
Z96.1
ICD-10 Finland
Presence of intraocular lens
1.5
14.2
454
3054
B01AB05
ATC
enoxaparin; parenteral
1.3
14.2
1239
10006
S01BA04
ATC
prednisolone; ophthalmic (corticosteroids, plain)
2.5
14.2
108
433
A10BA02
ATC
metformin; oral
1.3
14.1
1091
8650
TFC00
NOMESCO Finland
Catheterisation of right atrium or ventricle
3.0
14.1
81
273
S01BA01
ATC
dexamethasone; ophthalmic (corticosteroids, plain)
2.1
14.0
164
807
D07AD01
ATC
clobetasol; topical
1.4
14.0
632
4568
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
2.5
14.0
107
429
TFP00
NOMESCO Finland
Temporary use of transvenous or epicardial pacemaker
3.9
13.9
56
144
205
Kela drug reimbursment
Chronic hypertension
1.3
13.9
1060
8391
R42
ICD-10 Finland
Dizziness and giddiness
1.4
13.8
832
6337
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.4
13.8
630
4566
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
1.7
13.6
272
1618
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.6
13.6
375
2431
SPAT1153
SPAT
Removal of sutures
1.3
13.6
1318
10788
XF402
NOMESCO Finland
ECG with work load test
1.5
13.6
435
2925
H30.9
ICD-10 Finland
Chorioretinal inflammation, unspecified
12.0
13.6
24
20
E66.8
ICD-10 Finland
Other obesity
1.8
13.6
221
1230
E27.3
ICD-10 Finland
Drug-induced adrenocortical insufficiency
5.5
13.5
39
71
D80.8
ICD-10 Finland
Other immunodeficiencies with predominantly antibody defects
+∞
13.5
13
*
G53.2
ICD-10 Finland
Multiple cranial nerve palsies in sarcoidosis
+∞
13.5
13
*
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.4
13.5
635
4630
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.4
13.4
640
4675
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
1.8
13.4
216
1196
D07AC13
ATC
mometasone; topical
1.3
13.3
1190
9628
H40.4
ICD-10 Finland
Glaucoma secondary to eye inflammation
13.8
13.2
22
16
C09AA05
ATC
ramipril; oral
1.3
13.2
949
7431
ZXA10
NOMESCO Finland
Bilateral
1.4
13.2
719
5380
DM1AI
NOMESCO Finland
Cone beam CT of paranasal sinus
2.4
13.2
106
439
C09DX04
ATC
valsartan and sacubitril; oral
4.4
13.0
46
105
A10AE04
ATC
insulin glargine; parenteral
1.6
13.0
369
2412
N02AJ06
ATC
codeine and paracetamol; systemic
1.3
13.0
1561
13130
C08CA01
ATC
amlodipine; oral
1.3
13.0
1423
11829
A10BH01
ATC
sitagliptin; oral
1.6
12.9
368
2405
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
1.3
12.9
1038
8266
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.4
12.9
661
4893
XQ800
NOMESCO Finland
Prick test
1.6
12.7
298
1854
S97
ICPC
Chronic ulcer skin
1.8
12.7
206
1148
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
1.6
12.6
342
2210
A46
ICD-10 Finland
Erysipelas
1.4
12.6
547
3920
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.3
12.6
1129
9127
381
Kela drug reimbursment
Combination product containing sacubitril and valsartan
4.6
12.6
43
95
R05FB02
ATC
cough suppressants and expectorants
1.3
12.5
1569
13253
D80.0
ICD-10 Finland
Hereditary hypogammaglobulinaemia
+∞
12.5
12
*
M05BA07
ATC
risedronic acid; oral
2.1
12.4
135
646
J01DA01
ATC
[U] cefalexin; systemic
1.2
12.4
2750
24807
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.5
12.3
466
3250
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
1.7
12.3
281
1735
289
Kela drug reimbursment
Combination product containing sacubitril and valsartan
4.0
12.3
48
121
WX402
NOMESCO Finland
General anaesthesia
1.4
12.3
663
4948
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
1.6
12.3
302
1906
K80.2
ICD-10 Finland
Calculus of gallbladder without cholecystitis
1.5
12.2
455
3161
XF409
NOMESCO Finland
Other special ECG
4.7
12.2
40
85
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.3
12.2
1067
8592
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.3
12.1
830
6442
WX002
NOMESCO Finland
Sedation and analgesia
1.4
12.1
774
5944
DMB20
NOMESCO Finland
Functional endoscopic opening of maxillary antrum
1.8
12.1
221
1277
6952A
ICD-9 Finland
Erythematous conditions, Erythema nodosum[ERYTHEMA NODOSUM ACUTUM]
18.1
12.0
18
10
A10BK03
ATC
empagliflozin; oral
1.7
12.0
273
1686
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
1.7
11.9
237
1407
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.4
11.9
521
3741
GDA10
NOMESCO Finland
Biopsy of lung
11.7
11.8
21
18
GX1K5
NOMESCO Finland
Diffusion capacity
8.9
11.7
24
27
R03AK11
ATC
formoterol and fluticasone; inhalant
2.2
11.7
112
504
H53.1
ICD-10 Finland
Subjective visual disturbances
1.7
11.7
240
1437
N19
ICD-10 Finland
Unspecified kidney failure
2.2
11.6
120
561
WW200
NOMESCO Finland
Immunization
2.2
11.6
120
562
J05AB01
ATC
aciclovir; systemic
1.3
11.6
823
6422
FM1CN
NOMESCO Finland
Heart perfusion isotope imaging at rest
18.9
11.6
17
9
D83.9
ICD-10 Finland
Common variable immunodeficiency, unspecified
+∞
11.5
11
*
D80.3
ICD-10 Finland
Selective deficiency of immunoglobulin G [IgG] subclasses
+∞
11.5
11
*
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
1.6
11.4
279
1755
J02AC01
ATC
fluconazole; systemic
1.3
11.4
1618
13832
PJ2AT
NOMESCO Finland
Biopsy of lymphnode with ultrasound guidance
3.7
11.4
49
135
H26.2
ICD-10 Finland
Complicated cataract
3.0
11.4
63
210
I50.1
ICD-10 Finland
Left ventricular failure
1.9
11.4
160
847
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
1.7
11.3
231
1385
JN3BD
NOMESCO Finland
Extensive abdominal CT
1.5
11.3
426
2969
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
1.4
11.3
510
3685
A10AE05
ATC
insulin detemir; parenteral
1.7
11.2
219
1294
285
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
1.8
11.2
197
1130
K90.0
ICD-10 Finland
Coeliac disease
2.1
11.1
117
553
TDM10
NOMESCO Finland
Puncture of maxillary antrum
2.0
11.1
148
769
C09CA01
ATC
losartan; oral
1.3
11.1
944
7557
TFP34
NOMESCO Finland
Electrophysiological investigation
2.1
11.0
125
608
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
1.5
11.0
363
2454
FPJ24
NOMESCO Finland
Revision of biventricular cardioverter-defibrillator with atrial and ventricular electrodes
11.1
11.0
20
18
R03DC03
ATC
montelukast; oral
1.4
11.0
624
4695
SPAT1325
SPAT
Vaccination
1.3
11.0
1294
10807
M05BB03
ATC
alendronic acid and colecalciferol; oral
2.4
11.0
94
404
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.5
10.9
412
2872
A10BH05
ATC
linagliptin; oral
1.9
10.9
160
860
NA7DG
NOMESCO Finland
Spine and spinal cord very extensive MRI examination with high intensity magnet
3.2
10.9
56
178
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
1.7
10.8
225
1356
M79.6
ICD-10 Finland
Pain in limb
1.3
10.8
1440
12203
A06AC01
ATC
ispaghula (psylla seeds); oral
1.3
10.8
942
7565
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
1.7
10.8
202
1181
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.3
10.7
1176
9730
XG404
NOMESCO Finland
Peak expiratory flow (PEF) measurement
3.9
10.7
42
107
N03AX16
ATC
pregabalin; oral
1.3
10.7
941
7562
SPAT1249
SPAT
Treatment-related counselling outside office
1.2
10.7
1568
13430
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
1.5
10.6
323
2148
J05AB11
ATC
valaciclovir; oral
1.4
10.6
504
3673
L04AD01
ATC
ciclosporin; systemic
2.4
10.6
86
361
5188X
ICD-9 Finland
Other diseases of lung
11.2
10.5
19
17
R60.0
ICD-10 Finland
Localized oedema
1.5
10.5
399
2787
D38.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Trachea, bronchus and lung
2.2
10.4
104
480
A07AA02
ATC
nystatin; oral
1.7
10.4
233
1433
N08.2*D89.80
ICD-10 Finland
Immunoglobulin A (IgA) nephropathy
110.2
10.4
11
*
AA1AD
NOMESCO Finland
CT of head and brain
1.3
10.4
903
7243
A10BJ06
ATC
semaglutide; parenteral
2.0
10.3
133
682
I49.9
ICD-10 Finland
Cardiac arrhythmia, unspecified
1.4
10.3
427
3033
I50.0
ICD-10 Finland
Congestive heart failure
1.7
10.3
223
1359
R06.8
ICD-10 Finland
Other and unspecified abnormalities of breathing
2.8
10.2
64
230
J01MA02
ATC
ciprofloxacin; systemic
1.2
10.2
1563
13440
H47.1
ICD-10 Finland
Papilloedema, unspecified
4.9
10.2
32
66
S01EC01
ATC
acetazolamide; systemic
2.4
10.1
85
361
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.2
10.1
2202
19637
C85.9
ICD-10 Finland
Non-Hodgkin lymphoma, unspecified
4.4
10.1
35
80
R70.0
ICD-10 Finland
Elevated erythrocyte sedimentation rate
2.4
10.1
82
344
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.3
10.0
1136
9427
M10.9
ICD-10 Finland
Gout, unspecified
1.6
10.0
229
1417
R03AK03
ATC
[D] fenoterol & other drugs for obstructive airway dis; inhalant
1.8
9.9
173
989
H40.5
ICD-10 Finland
Glaucoma secondary to other eye disorders
3.2
9.9
50
158
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.3
9.8
816
6499
346
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
1.8
9.8
177
1022
M02.9
ICD-10 Finland
Reactive arthropathy, unspecified
2.7
9.8
66
249
R53
ICD-10 Finland
Malaise and fatigue
1.3
9.8
743
5847
XCH00
NOMESCO Finland
Eye pressure measurement
1.8
9.7
149
817
WX722
NOMESCO Finland
PEEP
1.7
9.7
180
1048
JN3AD
NOMESCO Finland
Abdominal CT examination
1.5
9.7
287
1898
NH3EA
NOMESCO Finland
Feet X-ray examination with load
2.3
9.7
89
398
H43.8
ICD-10 Finland
Other disorders of vitreous body
1.5
9.6
324
2209
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
1.5
9.6
287
1905
M13.0
ICD-10 Finland
Polyarthritis, unspecified
2.9
9.6
55
188
M80.4
ICD-10 Finland
Drug-induced osteoporosis with pathological fracture
6.0
9.5
25
42
N17.9
ICD-10 Finland
Acute renal failure, unspecified
1.9
9.5
139
752
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
1.8
9.5
152
846
UDQ12
NOMESCO Finland
Flexible laryngoscopy
1.6
9.5
217
1347
D64.9
ICD-10 Finland
Anaemia, unspecified
1.5
9.4
342
2365
M148, L529
ICD-10 Finland
NA
30.1
9.4
12
*
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.2
9.4
1943
17199
SPAT1255
SPAT
Intravenous administration of medicine
1.6
9.3
252
1628
JKA21
NOMESCO Finland
Laparoscopic cholecystectomy
1.4
9.3
423
3055
GD5AD
NOMESCO Finland
Thorax and upper abdomen combined CT examination of
2.8
9.3
57
205
A03FA01
ATC
metoclopramide; systemic, rectal
1.3
9.3
801
6411
R01AD08
ATC
fluticasone; nasal
1.3
9.3
1152
9650
FM1DM
NOMESCO Finland
Heart very extensive MRI examination with 3 Tesla magnet
8.7
9.3
19
22
FPJ22
NOMESCO Finland
Revision of cardioverter-defibrillator with atrial and ventricular electrodes
9.5
9.2
18
19
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
2.0
9.2
108
537
GD1AA
SPAT
NA
1.6
9.2
262
1716
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
2.0
9.2
118
609
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.4
9.2
437
3189
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
1.9
9.2
122
637
WX780
NOMESCO Finland
Remote monitoring CPAP
1.8
9.2
159
910
SPAT1310
SPAT
Counselling related to known health issue
1.2
9.1
1240
10493
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
1.6
9.1
242
1556
G62.9
ICD-10 Finland
Polyneuropathy, unspecified
1.9
9.1
126
667
AN1
HP
Coronary angiography
1.4
9.0
414
3003
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
1.7
9.0
178
1059
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
1.6
8.9
218
1376
G44.2
ICD-10 Finland
Tension-type headache
1.4
8.8
477
3556
TQW80
NOMESCO Finland
Local dermatologic skincare
2.1
8.8
100
492
ZX108
NOMESCO Finland
Inhalation
3.8
8.8
35
92
Z94.1
ICD-10 Finland
Heart transplant status
7.2
8.7
20
28
A02BA02
ATC
ranitidine; systemic
1.3
8.7
749
5990
B01AF02
ATC
apixaban; oral
1.5
8.7
326
2272
I49.5
ICD-10 Finland
Sick sinus syndrome
1.9
8.7
128
694
D07AB02
ATC
hydrocortisone butyrate; topical
1.2
8.7
1092
9159
TFP20
NOMESCO Finland
Cardiodefibrillation
1.5
8.6
249
1639
XG480
NOMESCO Finland
Histamine provocation of respiratroy tract
2.6
8.6
61
240
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.4
8.6
361
2570
DNB20
NOMESCO Finland
Endoscopic ethmoidectomy
2.0
8.6
109
560
N06AX21
ATC
duloxetine; oral
1.4
8.6
403
2932
B01AB04
ATC
dalteparin; parenteral
1.7
8.5
176
1063
R01AD01
ATC
beclometasone; nasal
1.3
8.5
606
4720
P01AB01
ATC
metronidazole; oral, rectal
1.2
8.5
1611
14104
G56.0
ICD-10 Finland
Carpal tunnel syndrome
1.4
8.5
508
3853
K02.1
ICD-10 Finland
Caries of dentine
1.2
8.5
2350
21316
FPH10
NOMESCO Finland
Open removal of transvenous cardiac pacemaker or cardioverter-defibrillator
7.3
8.4
19
26
R03BB04
ATC
tiotropium bromide; inhalant
1.4
8.4
339
2399
D84.8
ICD-10 Finland
Other specified immunodeficiencies
+∞
8.3
8
*
A10AB04
ATC
insulin lispro; parenteral (insulins and analog. for injection, fast-acting)
1.8
8.3
129
711
351
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
1.4
8.3
421
3105
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
1.7
8.3
175
1061
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.4
8.3
448
3343
01107
ICD-8 Finland
Pulmonary tuberculosis, Suspecta
7.1
8.2
19
27
R21
ICD-10 Finland
Rash and other nonspecific skin eruption
1.7
8.2
152
889
H53.2
ICD-10 Finland
Diplopia
1.9
8.2
116
619
R02
ICPC
Shortness of breath/dyspnoea
1.4
8.2
419
3093
J47
ICD-10 Finland
Bronchiectasis
2.3
8.2
70
304
R06AE07
ATC
cetirizine; oral
1.2
8.1
1755
15533
S01ED51
ATC
timolol, combinations; ophthalmic
1.5
8.1
250
1672
N03AX12
ATC
gabapentin; oral
1.3
8.0
584
4559
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
1.2
8.0
1917
17126
F2682
NOMESCO Finland
NA
10.0
8.0
15
15
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
2.8
8.0
49
178
SFA30
NOMESCO Finland
Filling on tree or more surfaces of tooth
1.2
8.0
1658
14619
KA1AE
NOMESCO Finland
Kidney ultrasound examination
2.0
8.0
93
461
6BA02
NOMESCO Finland
NA
5.9
8.0
21
36
M01AE02
ATC
naproxen; oral, rectal
1.2
8.0
2372
21605
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
1.8
8.0
124
686
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
1.5
8.0
304
2129
M79.0
ICD-10 Finland
Rheumatism, unspecified
1.8
7.9
133
752
I80.3
ICD-10 Finland
Phlebitis and thrombophlebitis of lower extremities, unspecified
1.8
7.9
137
787
S01FA02
ATC
scopolamine; ophthalmic
2.9
7.9
46
161
XCK00
NOMESCO Finland
Perimetry
1.5
7.9
239
1592
H40.0
ICD-10 Finland
Glaucoma suspect
1.5
7.8
271
1858
N18.0
ICD-10 Finland
End-stage renal disease
2.9
7.8
46
162
R55
ICD-10 Finland
Syncope and collapse
1.4
7.8
367
2668
SPAT1097
SPAT
Recording of ECG
1.3
7.8
561
4373
UDC00
NOMESCO Finland
Ear microscopy
1.5
7.8
250
1684
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
2.0
7.8
94
472
JN6DR
NOMESCO Finland
PET-CT of whole body metabolism
3.7
7.8
32
87
C03EA01
ATC
hydrochlorothiazide and potassium-sparing agents; oral
1.3
7.8
563
4392
FPE40
NOMESCO Finland
Replacement of transvenous cardiac pacemaker electrode
4.6
7.8
25
54
L17
ICPC
Foot/toe symptom/complaint
1.2
7.8
938
7814
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.4
7.8
435
3262
XQ848
NOMESCO Finland
Dermatological photography
2.0
7.7
96
492
H20.9
ICD-10 Finland
Iridocyclitis, unspecified
2.9
7.7
45
158
O99.5
ICD-10 Finland
Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium
4.2
7.7
27
64
R04.0
ICD-10 Finland
Epistaxis
1.5
7.7
241
1618
I45.3
ICD-10 Finland
Trifascicular block
5.5
7.7
21
38
M54.5
ICD-10 Finland
Low back pain
1.2
7.7
1277
11012
TDW99
NOMESCO Finland
Other minor procedure in surgery of ear, nose and larynx
1.8
7.6
114
624
M14.8*L52
ICD-10 Finland
Arthropathy in erythema: nodosum
25.0
7.6
10
*
R00.1
ICD-10 Finland
Bradycardia, unspecified
1.9
7.6
111
603
JN4KR
NOMESCO Finland
Whole body very extensive metabolic PET with CT
3.3
7.5
36
111
S01BA07
ATC
fluorometholone; ophthalmic (corticosteroids, plain)
2.2
7.5
69
312
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.2
7.5
960
8049
Z01.2
ICD-10 Finland
Dental examination
1.2
7.5
1604
14160
A10AD01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate- or long-acting comb. with fast-acting)
2.2
7.5
73
337
ND2DA
NOMESCO Finland
Bilateral hand X-ray examination
2.1
7.5
83
406
R03AC13
ATC
formoterol; inhalant
1.6
7.5
177
1109
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
2.0
7.4
92
471
A10BK01
ATC
dapagliflozin; oral
1.6
7.4
165
1016
SPAT1301
SPAT
No procedures
1.2
7.4
1188
10199
TNE25
NOMESCO Finland
Drill biopsy of bone marrow, pelvis
2.7
7.4
48
180
C07AB02
ATC
metoprolol; systemic
1.3
7.4
721
5853
S01BC03
ATC
diclofenac; ophthalmic
2.0
7.4
93
476
GX1E5
NOMESCO Finland
Flow volume spirometry and bronchodilation test
6.4
7.4
18
28
TK800
NOMESCO Finland
Hemodialysis
2.1
7.4
80
388
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
2.2
7.4
68
308
ASB
HP
Insertion of a biventricular physiological pacemaker DDD (R)
7.6
7.4
16
21
WX720
NOMESCO Finland
Own respiration
1.7
7.4
134
783
WX725
NOMESCO Finland
Noninvasive ventilation
1.6
7.4
166
1029
R06.5
ICD-10 Finland
Mouth breathing
1.4
7.3
325
2340
J90
ICD-10 Finland
Pleural effusion, not elsewhere classified
1.9
7.3
107
580
I89.9
ICD-10 Finland
Noninfective disorder of lymphatic vessels and lymph nodes, unspecified
8.4
7.3
15
18
D89.89
ICD-10 Finland
Other specified disorders involving the immune mechanism, not elsewhere classified
+∞
7.3
7
*
SPAT1149
SPAT
Suture or treatment of traumatic wound
1.3
7.3
470
3607
104
Kela drug reimbursment
Thyroid insufficiency
1.5
7.3
265
1837
R03BB01
ATC
ipratropium bromide; inhalant
1.8
7.2
116
649
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
1.4
7.2
303
2161
PJ3AT
NOMESCO Finland
Cytology of lymphnode with ultrasound guidance
2.7
7.2
47
177
J96.1
ICD-10 Finland
Chronic respiratory failure
2.2
7.2
66
297
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
1.5
7.2
270
1886
NH3DA
NOMESCO Finland
Bilateral foot X-ray examination
2.0
7.2
88
450
Z73.3
ICD-10 Finland
Stress, not elsewhere classified
2.4
7.2
55
228
127
Kela drug reimbursment
Transplant complication
2.3
7.2
63
278
L29
ICPC
Musculoskeletal sympt/complt other
1.5
7.2
254
1752
Y0499
ICD-8 Finland
Investigation of respiratory system
2.7
7.1
46
171
A10AB01
ATC
insulin (human); parenteral (insulins and analog. for injection, fast-acting)
1.7
7.1
135
797
R04.2
ICD-10 Finland
Haemoptysis
1.8
7.1
119
677
SFA20
NOMESCO Finland
Filling on two surfaces of tooth
1.2
7.1
2396
21968
L27.0
ICD-10 Finland
Generalized skin eruption due to drugs and medicaments
2.6
7.1
48
186
UKC02
NOMESCO Finland
Cystoscopy
1.3
7.1
527
4126
SPAT1254
SPAT
Administration of medicine
1.3
7.1
494
3836
QXA25
NOMESCO Finland
Destruction of lesion of skin, site unspecified
1.9
7.0
93
489
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
2.1
7.0
77
374
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
3.1
7.0
35
112
D37.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other digestive organs
2.0
7.0
88
451
QAA05
NOMESCO Finland
Incision for biopsy of skin of head or neck
2.0
7.0
80
398
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
1.6
7.0
151
928
R5599
NOMESCO Finland
Other rehabilitation service
1.9
6.9
96
513
WX723
NOMESCO Finland
CPAP therapy
1.7
6.9
128
753
F43.21
ICD-10 Finland
Adaptation disorder with prolonged depression
2.8
6.9
41
147
K76.0
ICD-10 Finland
Fatty (change of) liver, not elsewhere classified
1.9
6.9
100
544
R06AE09
ATC
levocetirizine; oral
1.3
6.9
516
4044
TFP52
NOMESCO Finland
Ablation treatment of ventricular tachycardia due to structural heart defect
13.8
6.9
11
8
FQA10
NOMESCO Finland
Orthotopic transplantation of heart with bicaval anastomosis
13.8
6.9
11
8
H43.1
ICD-10 Finland
Vitreous haemorrhage
2.0
6.9
85
436
H3603, E103
ICD-10 Finland
NA
2.6
6.8
48
188
R03DA04
ATC
theophylline; systemic, rectal
1.6
6.8
159
998
A41.9
ICD-10 Finland
Sepsis, unspecified
1.8
6.8
114
650
J86.00
ICD-10 Finland
Empyema with broncho-pleural fistula
9.3
6.8
13
14
I83.0
ICD-10 Finland
Varicose veins of lower extremities with ulcer
2.1
6.8
75
366
D80.2
ICD-10 Finland
Selective deficiency of immunoglobulin A [IgA]
40.1
6.8
8
*
I42.8
ICD-10 Finland
Other cardiomyopathies
3.6
6.7
28
78
B07.9
ICD-10 Finland
Verruca simplex
1.7
6.7
119
690
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.2
6.7
1794
16111
A12BA01
ATC
potassium chloride; oral
1.7
6.7
140
853
H35.39
ICD-10 Finland
Degeneration of macula and posterior pole
1.9
6.7
96
520
UJF92
NOMESCO Finland
Capsular endoscopy
2.0
6.7
75
371
D07BB04
ATC
hydrocortisone butyrate and antiseptics; topical
1.3
6.7
441
3395
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
1.7
6.7
136
822
CK2L4
NOMESCO Finland
Wide-field/panoramic imaging of ocular fundus
3.5
6.7
29
84
J84.8
ICD-10 Finland
Other specified interstitial pulmonary diseases
2.7
6.7
41
151
Z49.1
ICD-10 Finland
Extracorporeal dialysis
2.5
6.7
48
193
R93.8
ICD-10 Finland
Abnormal findings on diagnostic imaging of other specified body structures
3.7
6.6
27
74
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.3
6.6
416
3178
A10BB12
ATC
glimepiride; oral
1.5
6.6
230
1582
C09CA06
ATC
candesartan; oral
1.2
6.6
806
6712
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.2
6.6
877
7376
H26.4
ICD-10 Finland
After-cataract
1.4
6.5
280
2008
BA1AE
NOMESCO Finland
Thyroiid ultrasound examination
2.2
6.5
59
265
J20
ICD-10 Finland
Acute bronchitis
1.4
6.5
338
2506
M35.9
ICD-10 Finland
Systemic involvement of connective tissue, unspecified
2.4
6.5
50
207
SPAT1229
SPAT
Assessment of need for aid
1.4
6.5
271
1930
S01CA02
ATC
prednisolone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
2.4
6.5
51
215
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.3
6.5
517
4087
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.3
6.5
627
5081
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
1.4
6.5
313
2293
R05DA20
ATC
opium alkaloids and derivatives - combinations
1.2
6.5
981
8361
XG460
NOMESCO Finland
Short time oxymetry
2.2
6.4
63
292
I41.8*M05.3
ICD-10 Finland
Rheumatoid myocarditis
69.9
6.4
7
*
D59.9
ICD-10 Finland
Acquired haemolytic anaemia, unspecified
7.4
6.4
14
19
B99
ICD-10 Finland
Other and unspecified infectious diseases
2.1
6.4
66
316
I45.2
ICD-10 Finland
Bifascicular block
4.7
6.4
20
43
GD1AT
NOMESCO Finland
Biopsy of the lung with ultrasound guidance
4.7
6.4
20
43
I48.0
ICD-10 Finland
Paroxysmal atrial fibrillation
1.5
6.4
202
1361
T86.0
ICD-10 Finland
Bone-marrow transplant rejection
8.1
6.3
13
16
GX1D5
NOMESCO Finland
Flow volume spirometry
8.1
6.3
13
16
KBV02
NOMESCO Finland
Cystoscopic insertion of stent into ureter
2.0
6.3
70
346
N20.1
ICD-10 Finland
Calculus of ureter
1.6
6.3
134
821
H30.1
ICD-10 Finland
Disseminated chorioretinal inflammation
11.0
6.3
11
10
R99
ICPC
Respiratory disease other
2.1
6.3
63
299
I42.1
ICD-10 Finland
Obstructive hypertrophic cardiomyopathy
3.8
6.3
24
63
KBV12
NOMESCO Finland
Transluminal endoscopic removal of stent from ureter
2.5
6.2
45
181
D80.6
ICD-10 Finland
Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia
+∞
6.2
6
*
1230
FHL
Bronchomediastinoscopy
+∞
6.2
6
*
E10.2
ICD-10 Finland
Type 1 diabetes mellitus, With renal complications
2.8
6.2
37
133
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
1.4
6.2
259
1849
GEA96
NOMESCO Finland
Other mediastinoscopic procedure
26.7
6.2
8
*
KBE12
NOMESCO Finland
Transluminal endoscopic extraction of calculus of ureter
2.6
6.2
41
157
R01BA52
ATC
pseudoephedrine, combinations; oral
1.2
6.2
1239
10834
M03BA52
ATC
carisoprodol, combinations excl. psycholeptics; oral
1.6
6.2
136
840
XG466
NOMESCO Finland
Sleep oxymetry
1.7
6.2
121
725
C08CA02
ATC
felodipine; oral
1.4
6.2
303
2225
R20.2
ICD-10 Finland
Paraesthesia of skin
1.5
6.2
223
1549
K52.88
ICD-10 Finland
Other specified noninfective gastroenteritis and colitis
1.9
6.2
86
463
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
1.5
6.2
174
1144
FPG30
NOMESCO Finland
Implantation of cardioverter-defibrillator with ventricular electrode
3.2
6.2
29
90
XW4AT
NOMESCO Finland
Biopsy of other inner organ with ultrasound guidance
4.5
6.1
20
45
A07EC02
ATC
mesalazine; oral, rectal
1.5
6.1
195
1319
CJB10
NOMESCO Finland
Laser discission of secondary cataract
1.4
6.1
245
1732
A11CC03
ATC
alfacalcidol; systemic
1.9
6.1
77
399
A10BJ02
ATC
liraglutide; parenteral
1.9
6.1
87
471
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
1.5
6.1
219
1520
R03AC12
ATC
salmeterol; inhalant
1.6
6.1
143
900
JN6AD
NOMESCO Finland
CT of torso and neck
2.4
6.1
47
197
TQW99
NOMESCO Finland
Other minor procedure on skin
1.5
6.1
168
1099
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
2.0
6.0
72
364
JAL01
NOMESCO Finland
Laparoscopic biopsy of peritoneum
4.4
6.0
20
46
A01AB09
ATC
miconazole; local oral
1.4
6.0
306
2262
3039X
ICD-9 Finland
Alcohol dependence syndrome, Other and unspecified alcohol dependence
0.1
6.0
*
232
Mortality – FinRegistry
↥Association
Association between endpoint D3_SARCOIDOSIS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| D3_SARCOIDOSIS | 1.39 [1.25, 1.54] | < 0.001 |
| Birth year | 0.998 [0.99, 1.01] | 0.711 |
During the follow-up period (1.1.1998 — 31.12.2019), 1208 out of 9966 females with D3_SARCOIDOSIS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| D3_SARCOIDOSIS | 1.389 [1.25, 1.54] | < 0.001 |
| Birth year | 0.987 [0.98, 1.0] | 0.005 |
During the follow-up period (1.1.1998 — 31.12.2019), 1134 out of 8918 males with D3_SARCOIDOSIS died.
Mortality risk
Mortality risk for people of age
years, who have D3_SARCOIDOSIS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.134% | 0.329% |
| 5 | 0.738% | 1.766% |
| 10 | 2.088% | 3.93% |
| 15 | 4.361% | 7.144% |
| 20 | 7.682% | 12.149% |
Relationships between endpoints
↥Index endpoint: D3_SARCOIDOSIS – Sarcoidosis
GWS hits: 21
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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