≡ Risteys
FG R12 + FR

Documentation Changelog GitHub Contact & Feedback

Malnutrition

DOID EFO Endpoint Browser PheWeb

E4_MALNUTRITION

protein energy malnutrition: A nutritional deficit that is caused by inadequate protein or calorie intake.

Suggest a new description

Endpoint definition

↥

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — E40-E46
  • Cause of death: ICD-10 — E40-E46

2 out of 7 registries used, show all original rules.

660

4. Check minimum number of events

None

660

5. Include endpoints

700

6. Filter based on genotype QC (FinnGen only)

700

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
2
First used in FinnGen datafreeze
DF2

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 9178 5172 3965
Only index persons 7591 4380 3211
Unadjusted period prevalence (%)
Whole population 0.13 0.15 0.11
Only index persons 0.14 0.16 0.12
Median age at first event (years)
Whole population 67.39 70.70 63.06
Only index persons 68.88 71.80 64.89

-FinnGen-

Key figures

All Female Male
Number of individuals 700 386 314
Unadjusted period prevalence (%) 0.13 0.13 0.14
Median age at first event (years) 63.37 61.28 65.94

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
615
Matched controls
6149
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
E44.0
ICD-10 Finland
Moderate protein-energy malnutrition
+∞
173.3
158
*
E46
ICD-10 Finland
Unspecified protein-energy malnutrition
+∞
168.7
154
*
E44.1
ICD-10 Finland
Mild protein-energy malnutrition
1036.3
93.4
89
*
E42
ICD-10 Finland
Marasmic kwashiorkor
+∞
77.8
73
*
E43
ICD-10 Finland
Unspecified severe protein-energy malnutrition
+∞
51.8
49
*
E41
ICD-10 Finland
Nutritional marasmus
+∞
48.6
46
*
601
Kela drug reimbursment
Severe malabsorption of nutrients, mainly fats
31.7
35.7
47
16
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
3.9
35.6
173
563
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
15.5
34.9
58
41
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
7.7
34.6
84
124
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.8
33.4
166
547
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.6
30.0
154
516
R63.4
ICD-10 Finland
Abnormal weight loss
8.0
29.1
68
94
E40
ICD-10 Finland
Kwashiorkor
+∞
27.3
26
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.8
26.9
235
1128
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.8
25.8
215
998
602
Kela drug reimbursment
Children's severe malnutrition
16.4
24.9
40
26
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
2.5
22.1
239
1259
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.3
21.7
303
1814
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
3.9
21.6
94
269
E86
ICD-10 Finland
Volume depletion
7.4
21.5
52
76
E45
ICD-10 Finland
Retarded development following protein-energy malnutrition
+∞
20.9
20
*
R53
ICD-10 Finland
Malaise and fatigue
2.6
20.3
179
838
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.4
20.2
240
1312
A28
ICPC
Limited function/disability NOS
2.8
19.2
145
616
AA1AD
NOMESCO Finland
CT of head and brain
2.5
19.2
179
861
A03FA01
ATC
metoclopramide; systemic, rectal
2.7
19.1
153
675
E87.6
ICD-10 Finland
Hypokalaemia
6.5
19.1
50
82
SPAT1222
SPAT
Counselling/guidance promoting independent living
2.9
19.0
135
551
N05AX08
ATC
risperidone; systemic
3.8
18.5
83
243
N02AA05
ATC
oxycodone; systemic
3.0
18.2
119
461
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
4.1
18.0
74
200
L28
ICPC
Limited function/disability (L)
2.8
18.0
133
557
TPH07
NOMESCO Finland
Cathetrisation of artery
3.2
18.0
104
370
N05AH03
ATC
olanzapine; systemic
5.2
17.5
55
113
R4190
NOMESCO Finland
Nutritional therapy
4.5
17.5
64
155
SPAT1262
SPAT
Handing over of treatment supplies
2.6
17.3
142
628
A49.9
ICD-10 Finland
Bacterial infection, unspecified
3.1
16.7
97
345
B03BA03
ATC
hydroxocobalamin; parenteral
4.1
15.9
64
170
TJD20
NOMESCO Finland
Change of gastrostomy tube
16.2
15.8
25
16
26899
ICD-8 Finland
Nutritional marasmus
+∞
15.7
15
*
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.5
15.4
136
625
R63.0
ICD-10 Finland
Anorexia
32.6
14.9
19
6
TPX10
NOMESCO Finland
Implantation of vascular injection port
6.8
14.8
37
57
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
3.3
14.8
77
253
UGC12
NOMESCO Finland
Flexible bronchoscopy
3.5
14.7
71
221
JF1AB
NOMESCO Finland
Passage examination of small bowell with X-ray
9.2
14.6
30
34
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
4.2
14.4
56
144
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
4.5
14.4
51
120
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
4.9
14.3
47
102
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
6.3
14.3
38
64
JDB10
NOMESCO Finland
Percutaneous gastrostomy
8.3
14.2
31
39
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.9
14.0
91
346
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
3.0
13.9
87
325
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
6.7
13.9
35
55
N17.9
ICD-10 Finland
Acute renal failure, unspecified
5.0
13.2
42
88
N03AX09
ATC
lamotrigine; oral
4.8
13.2
44
97
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.4
13.1
123
582
R11
ICD-10 Finland
Nausea and vomiting
2.9
12.9
81
301
RD210
NOMESCO Finland
NA
5.5
12.6
37
71
D64.9
ICD-10 Finland
Anaemia, unspecified
2.7
12.5
93
384
EBA15
NOMESCO Finland
Extraction of large number of teeth
4.4
12.5
45
108
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
2.0
12.4
213
1301
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
3.7
12.4
54
154
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
3.8
12.2
52
146
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
3.8
12.1
51
142
SPAT1216
SPAT
Assessment of functional ability
2.3
12.1
121
589
SPAT1229
SPAT
Assessment of need for aid
2.9
12.0
76
283
R13
ICD-10 Finland
Dysphagia
3.4
12.0
58
181
A06AD11
ATC
lactulose; oral
2.3
11.9
118
570
JAH00
NOMESCO Finland
Laparotomy
5.1
11.9
37
76
I95.1
ICD-10 Finland
Orthostatic hypotension
4.3
11.9
44
109
Z01.8
ICD-10 Finland
Other specified special examinations
2.1
11.8
145
775
S97
ICPC
Chronic ulcer skin
3.6
11.7
54
162
T08
ICPC
Weight loss
6.9
11.6
28
42
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
3.6
11.5
52
154
N05BA04
ATC
oxazepam; oral
2.1
11.4
160
900
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.4
11.4
107
501
F10.25
ICD-10 Finland
Alcohol dependence continuous use
9.9
11.3
22
23
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
4.2
11.2
42
105
SPAT1301
SPAT
No procedures
1.9
11.2
218
1388
K56.6
ICD-10 Finland
Other and unspecified intestinal obstruction
4.6
11.1
38
87
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
3.2
11.1
58
192
F50.0
ICD-10 Finland
Anorexia nervosa
14.2
11.0
18
13
C03CA01
ATC
furosemide; systemic
1.9
11.0
207
1298
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
7.1
11.0
26
38
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
2.0
10.9
179
1068
A02BC02
ATC
pantoprazole; systemic
1.8
10.8
361
2735
F10.29
ICD-10 Finland
Addiction caused by alcohol UNS
7.8
10.8
24
32
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
2.9
10.7
65
238
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
2.0
10.6
146
812
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
2.7
10.4
72
286
R1100
NOMESCO Finland
General evaluation of the need for rehabilitation
6.2
10.4
27
45
K91.2
ICD-10 Finland
Postsurgical malabsorption, not elsewhere classified
33.1
10.4
13
*
F50.9
ICD-10 Finland
Eating disorder, unspecified
10.9
10.3
19
18
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
2.6
10.2
75
309
WX408
NOMESCO Finland
General anesthesy, balanced
1.9
10.2
177
1071
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.7
10.2
70
277
A09AA02
ATC
multienzymes (lipase, protease etc.)
6.6
10.1
25
39
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.9
10.1
62
228
SPAT1254
SPAT
Administration of medicine
2.1
10.0
120
629
SPAT1249
SPAT
Treatment-related counselling outside office
1.8
10.0
240
1621
G40.9
ICD-10 Finland
Epilepsy, unspecified
4.2
10.0
37
92
130
Kela drug reimbursment
Malignant tumour
2.7
10.0
67
262
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.6
10.0
75
312
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
3.2
9.9
51
168
L89
ICD-10 Finland
Decubitus ulcer and pressure area
6.0
9.8
26
45
SPAT1255
SPAT
Intravenous administration of medicine
3.1
9.7
54
185
I50.9
ICD-10 Finland
Heart failure, unspecified
2.2
9.6
109
558
R33
ICD-10 Finland
Retention of urine
2.8
9.6
63
242
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.6
9.6
73
306
N05AH04
ATC
quetiapine; oral
2.2
9.5
102
506
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.3
9.5
93
442
W19
ICD-10 Finland
Unspecified fall
2.5
9.5
78
341
S72.1
ICD-10 Finland
Pertrochanteric fracture
5.0
9.4
29
60
OAB73
NOMESCO Finland
Prevention and treatment of malnutrition
12.6
9.4
16
13
SPAT1310
SPAT
Counselling related to known health issue
1.8
9.4
204
1329
V03AG01
ATC
sodium cellulose phosphate; systemic
22.1
9.4
13
6
ZX120
NOMESCO Finland
Intravenous
2.5
9.3
74
317
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
7.5
9.3
21
29
Z51.5
ICD-10 Finland
Palliative care
3.1
9.3
50
170
S01.0
ICD-10 Finland
Open wound of scalp
2.8
9.3
59
224
UJF32
NOMESCO Finland
Coloscopy
1.9
9.2
162
984
K59.09
ICD-10 Finland
Constipation, unspecified
2.8
9.1
57
213
R50.9
ICD-10 Finland
Fever, unspecified
2.1
9.1
109
569
JN3AD
NOMESCO Finland
Abdominal CT examination
2.9
9.1
56
207
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
3.0
9.1
52
184
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.1
9.0
103
527
R56.8
ICD-10 Finland
Other and unspecified convulsions
3.2
9.0
46
151
SPAT1263
SPAT
Sampling
1.7
8.9
257
1819
JN4CD
NOMESCO Finland
Very extensive body CT
4.0
8.9
34
88
M81.9
ICD-10 Finland
Osteoporosis, unspecified
3.6
8.8
39
114
N06AX11
ATC
mirtazapine; oral
1.8
8.8
180
1147
JN4AD
NOMESCO Finland
Body CT examination
3.0
8.8
51
182
S42.2
ICD-10 Finland
Fracture of upper end of humerus
3.5
8.8
40
120
F29
ICD-10 Finland
Unspecified nonorganic psychosis
4.5
8.7
30
70
OAB74
NOMESCO Finland
Nutritional guidance related to treatment and rehabilitation for medical condition
14.3
8.7
14
10
WX302
NOMESCO Finland
Thoracal epidural anesthesy
3.2
8.7
45
149
T36
ICD-10 Finland
Poisoning by systemic antibiotics
3.9
8.7
34
90
B81
ICPC
Anaemia vit B12/folate deficiency
3.6
8.6
37
106
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
3.4
8.6
41
128
GD1AD
NOMESCO Finland
Thorax CT examination
4.8
8.5
27
58
P15
ICPC
Chronic alcohol abuse
5.8
8.5
23
41
H02AB09
ATC
hydrocortisone; systemic
3.9
8.5
34
92
N06AB10
ATC
escitalopram; oral
2.0
8.5
109
587
F32.11
ICD-10 Finland
Moderate depressive episode with somatic syndrome
5.2
8.4
25
50
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
2.9
8.4
50
182
S72.0
ICD-10 Finland
Fracture of neck of femur
3.4
8.4
39
119
NFJ54
NOMESCO Finland
Internal fixation of fracture of upper femur with intramedullary nail
6.4
8.4
21
34
L04AD02
ATC
tacrolimus; systemic (calcineurin inhibitors)
9.6
8.3
16
17
N03AG01
ATC
valproic acid; systemic, rectal
3.0
8.3
47
164
A04
ICPC
Weakness/tiredness general
2.1
8.3
96
495
R60.0
ICD-10 Finland
Localized oedema
2.3
8.2
80
378
R63.8
ICD-10 Finland
Other symptoms and signs concerning food and fluid intake
14.7
8.2
13
9
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
2.4
8.2
70
310
133
Kela drug reimbursment
Severe chronic pancreatic insufficiency
7.7
8.2
18
24
NK6MA
NOMESCO Finland
Measurement of bone age from hand and elbow using X-ray
4.2
8.1
29
71
N04AA02
ATC
biperiden; systemic
6.0
8.0
21
36
L04AX01
ATC
azathioprine; systemic
3.4
8.0
38
118
K23.8*B37.8
ICD-10 Finland
Esophagitis caused by candidiasis
22.4
8.0
11
5
Z98.8
ICD-10 Finland
Other specified postsurgical states
7.4
8.0
18
25
JN4BD
NOMESCO Finland
Extensive body CT
2.3
7.9
71
324
H03AA01
ATC
levothyroxine sodium; systemic
1.9
7.9
139
838
SPAT1137
SPAT
Taking care of patient’s/customer’s hygiene
2.6
7.8
54
216
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
3.3
7.8
38
121
N06AB04
ATC
citalopram; systemic
1.9
7.8
123
713
SPAT1281
SPAT
Other administrative function
2.5
7.7
59
248
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.7
7.7
241
1726
F50.1
ICD-10 Finland
Atypical anorexia nervosa
12.0
7.6
13
11
T91
ICPC
Vitamin/nutritional deficiency
12.0
7.6
13
11
N05CF01
ATC
zopiclone; oral
1.7
7.6
190
1277
JDD00
NOMESCO Finland
Total gastrectomy and Roux-en-Y oesophagojejunostomy
25.4
7.6
10
*
C03DA01
ATC
spironolactone; oral
2.2
7.5
78
382
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
4.5
7.5
25
57
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.1
7.5
90
468
SPAT1312
SPAT
General health counselling
1.7
7.5
210
1457
TQW11
NOMESCO Finland
Vacuum treatment of wound
6.6
7.5
18
28
SPAT1260
SPAT
Consultation of another employee
1.9
7.4
107
601
E83.4
ICD-10 Finland
Disorders of magnesium metabolism
81.0
7.4
8
*
SPAT1240
SPAT
Therapeutic discussion
2.3
7.4
66
303
F03
ICD-10 Finland
Unspecified dementia
3.0
7.4
42
148
SPAT1245
SPAT
Provision of support and information to patient’s family members
3.1
7.2
38
129
Z46.8
ICD-10 Finland
Fitting and adjustment of other specified devices
4.0
7.2
27
70
M81.8
ICD-10 Finland
Other osteoporosis
8.1
7.1
15
19
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
2.9
7.1
41
146
127
Kela drug reimbursment
Transplant complication
5.7
7.1
19
34
M80.9
ICD-10 Finland
Unspecified osteoporosis with pathological fracture
5.7
7.1
19
34
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
3.4
7.1
33
102
R41.0
ICD-10 Finland
Disorientation, unspecified
3.3
7.0
33
103
J01MA02
ATC
ciprofloxacin; systemic
1.6
6.9
214
1520
SPAT1153
SPAT
Removal of sutures
1.7
6.9
176
1187
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
2.7
6.9
46
181
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
2.8
6.9
41
151
TJD00
NOMESCO Finland
Insertion of nasogastric or naso-gastroduodenal tube
5.1
6.8
20
40
N06AX21
ATC
duloxetine; oral
2.3
6.8
62
286
G72.8
ICD-10 Finland
Other specified myopathies
6.8
6.8
16
24
N06AX16
ATC
venlafaxine; oral
2.2
6.8
71
349
F60.9
ICD-10 Finland
Personality disorder, unspecified
9.5
6.8
13
14
A04AA01
ATC
ondansetron; systemic, rectal
2.7
6.8
45
177
NE1AA
NOMESCO Finland
Pelvis X-ray examination
2.5
6.8
53
226
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
2.2
6.7
68
329
K90.3
ICD-10 Finland
Pancreatic steatorrhoea
22.8
6.7
9
*
Z93.1
ICD-10 Finland
Gastrostomy status
22.8
6.7
9
*
SPAT1125
SPAT
Stoma care and guidance
5.3
6.7
19
37
F10.20
ICD-10 Finland
Alcohol dependence currently independent
6.5
6.7
16
25
N91.1
ICD-10 Finland
Secondary amenorrhoea
6.0
6.6
17
29
A07AA02
ATC
nystatin; oral
2.7
6.6
43
166
SPAT1149
SPAT
Suture or treatment of traumatic wound
2.1
6.6
78
405
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
2.1
6.6
76
391
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
2.4
6.6
53
232
N05CD07
ATC
temazepam; oral
2.1
6.6
76
392
F32.00
ICD-10 Finland
Mild depressive episode without somatic syndrome
3.4
6.5
29
87
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.8
6.5
129
808
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
2.3
6.5
57
260
JDB01
NOMESCO Finland
Laparoscopic gastrostomy
70.5
6.4
7
*
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
5.0
6.4
19
39
EP1AE
NOMESCO Finland
Neck ultrasound examination
2.9
6.4
37
133
F45.4
ICD-10 Finland
Persistent somatoform pain disorder
6.7
6.4
15
23
K08.3
ICD-10 Finland
Retained dental root
2.6
6.3
44
175
183
Kela drug reimbursment
Lamotrigin and topiramate
6.1
6.3
16
27
U04
ICPC
Incontinence urine
2.9
6.3
36
127
EB1CI
NOMESCO Finland
Cone beam imaging of teeth and jaws (3-4 quarters)
11.2
6.3
11
10
R4180
NOMESCO Finland
Podiatric therapy
9.4
6.3
12
13
A02BC05
ATC
esomeprazole; systemic
1.6
6.3
209
1503
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
2.9
6.3
37
135
WX882
NOMESCO Finland
High dependency care
2.9
6.3
36
128
G62.9
ICD-10 Finland
Polyneuropathy, unspecified
3.5
6.3
27
79
E83.39
ICD-10 Finland
Other disorder of phosphorus metabolism
+∞
6.3
6
*
C09.9
ICD-10 Finland
Malignant neoplasm: Tonsil, unspecified
+∞
6.3
6
*
M03BX01
ATC
baclofen; systemic
7.1
6.2
14
20
R64
ICD-10 Finland
Cachexia
27.0
6.2
8
*
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.4
6.2
48
206
TPH04
NOMESCO Finland
Cathetrisation of vein
1.7
6.2
126
790
QXB99
NOMESCO Finland
Other procedure to treat skin wound, unspecified location
5.8
6.2
16
28
ZXA00
NOMESCO Finland
Right side
1.7
6.2
159
1068
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
3.4
6.2
28
86
N05AA02
ATC
levomepromazine; systemic
3.4
6.2
28
86
L04AD01
ATC
ciclosporin; systemic
4.7
6.1
19
41
K59.1
ICD-10 Finland
Functional diarrhoea
2.8
6.1
37
138
Z49.1
ICD-10 Finland
Extracorporeal dialysis
8.7
6.1
12
14
F10.24
ICD-10 Finland
Alcohol depence active use
10.2
6.0
11
11
NFB20
NOMESCO Finland
Primary partial prosthetic replacement of hip joint using cement, other or unspecified
3.7
6.0
24
66

Mortality – FinRegistry

↥

Association

Association between endpoint E4_MALNUTRITION and mortality.

Females

Parameter HR [95% CI] p-value
E4_MALNUTRITION 3.526 [2.72, 4.58] < 0.001
Birth year 0.994 [0.99, 1.0] 0.157

During the follow-up period (1.1.1998 — 31.12.2019), 1285 out of 3662 females with E4_MALNUTRITION died.

Males

Parameter HR [95% CI] p-value
E4_MALNUTRITION 4.659 [3.32, 6.54] < 0.001
Birth year 0.987 [0.98, 1.0] 0.006

During the follow-up period (1.1.1998 — 31.12.2019), 1087 out of 2742 males with E4_MALNUTRITION died.

Mortality risk

Mortality risk for people of age

years, who have E4_MALNUTRITION.

N-year risk Females Males
1 0.257% 1.008%
5 1.853% 5.19%
10 4.843% 12.782%
15 8.936% 22.768%
20 15.271% 36.475%

Relationships between endpoints

↥

Index endpoint: E4_MALNUTRITION – Malnutrition

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
loading spinner Loading data