Mood [affective] disorders


mood disorder: A cognitive disorder a disturbance in which the person's mood is hypothesized to be the main underlying feature.

Endpoint definition

FinnGen phenotype data

414262 individuals

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Apply sex-specific rule None


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Check conditions None


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Check pre-conditions, main-only, mode, registry filters None

0 out of 7 registries used, show all original rules.


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Check minimum number of events None


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Remove individuals based on genotype QC


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Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 48085 31777 16308
Unadjusted prevalence (%) 12.75 15.07 9.81
Mean age at first event (years) 41.15 39.75 43.86


Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.49 [2.14, 2.89] 1.2e-32 3465
15 years 0.01 1.77 [1.57, 1.99] 2.3e-21 1497
5 years 0.00 3.09 [2.79, 3.43] 1.7e-100 794
1 year 0.00 7.61 [6.61, 8.76] <1e-100 381

Age distribution of first events

Year distribution of first events

Cumulative Incidence


Index endpoint: F5_MOOD – Mood [affective] disorders
GWS hits: 20

Survival analyses between endpoints


before Mood [affective] disorders
after Mood [affective] disorders

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Drugs most likely to be purchased after Mood [affective] disorders

Not a core endpoint, no data to show.