Parkinson's disease

G6_PARKINSON

Parkinson's disease: A progressive degenerative disorder of the central nervous system characterized by loss of dopamine producing neurons in the substantia nigra and the presence of Lewy bodies in the substantia nigra and locus coeruleus. Signs and symptoms include tremor which is most pronounced during rest, muscle rigidity, slowing of the voluntary movements, a tendency to fall back, and a mask-like facial expression.

Suggest a new description

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

None

473681

2. Check conditions

None

473681

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 G20
  • Hospital discharge: ICD-9 3320A
  • Hospital discharge: ICD-8 34200
  • Cause of death: ICD-10 G20
  • Cause of death: ICD-9 3320A
  • Cause of death: ICD-8 34200
  • KELA reimbursements: KELA codes 110

3 out of 7 registries used, show all original rules.

5309

4. Check minimum number of events

None

5309

5. Include endpoints

None

5309

6. Filter based on genotype QC (FinnGen only)

5150

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
G20-G26
Name in latin
Morbus Parkinson

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 65870 29924 34815
Only index persons 43747 19998 23749
Unadjusted period prevalence (%)
Whole population 0.92 0.86 0.97
Only index persons 0.83 0.74 0.91
Median age at first event (years)
Whole population 71.52 72.00 71.11
Only index persons 71.27 71.90 70.73

-FinnGen-

Key figures

All Female Male
Number of individuals 5150 2053 3097
Unadjusted period prevalence (%) 1.26 0.81 1.56
Median age at first event (years) 69.01 67.54 69.98

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
5305
Matched controls
53057
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
N87
ICPC
Parkinsonism
271.8
323.0
1417
71
G25.9
ICD-10 Finland
Extrapyramidal and movement disorder, unspecified
51.8
323.0
562
121
N04BC09
ATC
rotigotine; transdermal
227.7
323.0
361
17
N04BX02
ATC
entacapone; oral
+∞
323.0
413
*
F02.39*G20
ICD-10 Finland
Dementia in Parkinson's disease without information on additional symptoms
+∞
323.0
563
*
N04BA03
ATC
levodopa, decarboxylase inhibitor and COMT inhibitor; oral
7427.3
323.0
1187
*
N04BA02
ATC
levodopa and decarboxylase inhibitor; oral
483.7
323.0
4016
340
R25.1
ICD-10 Finland
Tremor, unspecified
18.8
323.0
905
573
110
Kela drug reimbursment
Parkinson's disease and comparable movement disrorders
+∞
323.0
4443
*
193
Kela drug reimbursment
Rasagiline
+∞
323.0
709
*
N04AA02
ATC
biperiden; systemic
20.7
323.0
526
281
N04BD01
ATC
selegiline; oral
701.5
323.0
1792
38
N04BC05
ATC
pramipexole; oral
13.6
323.0
1837
1994
N04BC04
ATC
ropinirole; oral
229.9
323.0
1052
57
N04BD02
ATC
rasagiline; oral
10356.2
323.0
879
*
G20
ICD-10 Finland
Parkinson disease
6465.2
323.0
4650
49
N05AH04
ATC
quetiapine; oral
4.4
317.4
1336
3737
N06DA03
ATC
rivastigmine; oral, transdermal
7.4
315.8
813
1263
N03AE01
ATC
clonazepam; systemic
5.6
215.0
686
1378
AAG20
NOMESCO Finland
Stereotactic intracranial implantation of electrodes
293.6
194.4
197
7
N04BB01
ATC
amantadine; oral
13.4
188.5
340
270
G21.9
ICD-10 Finland
Secondary parkinsonism, unspecified
64.9
176.9
206
33
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
4.7
176.1
661
1571
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
4.1
156.0
674
1824
C07AA05
ATC
propranolol; systemic
2.8
147.4
1141
4758
AEA50
NOMESCO Finland
Adjustment of implanted neurostimulator
114.0
142.8
155
14
AA5EN
NOMESCO Finland
Brain reseptor or transprot protein distribution isotope imaging
69.0
139.6
161
24
F02.39
ICD-10 Finland
Dementia in Parkinson's disease without information on additional symptoms
701.2
139.5
137
*
G04BD12
ATC
mirabegron; oral
2.9
136.6
937
3598
H02AA02
ATC
fludrocortisone; oral
16.8
128.6
210
130
G23.9
ICD-10 Finland
Degenerative disease of basal ganglia, unspecified
90.6
126.7
141
16
3320A
ICD-9 Finland
Parkinson's disease, Paralysis agitans
+∞
117.1
112
*
R53
ICD-10 Finland
Malaise and fatigue
2.3
116.0
1376
7091
I95.1
ICD-10 Finland
Orthostatic hypotension
4.4
114.8
443
1065
N05AH03
ATC
olanzapine; systemic
4.5
111.2
420
987
F20.9
ICD-10 Finland
Schizophrenia, unspecified
9.2
108.6
236
268
A28
ICPC
Limited function/disability NOS
2.3
108.0
1274
6515
A06AD11
ATC
lactulose; oral
2.3
107.1
1240
6280
G25.0
ICD-10 Finland
Essential tremor
5.8
106.9
322
588
AA1AD
NOMESCO Finland
CT of head and brain
2.0
101.0
1660
9748
N04BC02
ATC
pergolide; oral
254.8
98.0
100
*
SPAT1229
SPAT
Assessment of need for aid
2.7
95.2
712
2834
N05AH02
ATC
clozapine; systemic
11.6
92.0
176
157
XF606
NOMESCO Finland
Ortostatic test
12.5
90.9
167
137
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
3.0
90.6
581
2094
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.9
87.7
1872
11968
L28
ICPC
Limited function/disability (L)
2.1
86.6
1159
6181
N04BC06
ATC
cabergoline; oral (dopamine agonists)
27.2
80.7
112
42
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.8
79.2
1706
10843
N05AF03
ATC
chlorprothixene; systemic
6.0
79.0
227
390
F20.00
ICD-10 Finland
Paranoid schizophrenia continuous
8.3
78.7
181
226
G23.1
ICD-10 Finland
Progressive supranuclear ophthalmoplegia [Steele-Richardson-Olszewski]
81.4
78.3
88
11
XA800
NOMESCO Finland
Neuropsychological investigation
4.4
77.4
299
714
N06AX11
ATC
mirtazapine; oral
1.8
76.6
1658
10530
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
2.9
76.4
513
1895
N05BA04
ATC
oxazepam; oral
1.9
74.7
1372
8216
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.0
74.5
1140
6371
G25.2
ICD-10 Finland
Other specified forms of tremor
18.1
74.2
117
66
SPAT1216
SPAT
Assessment of functional ability
2.0
73.9
1123
6255
N05AX08
ATC
risperidone; systemic
2.6
71.1
589
2463
N05AF05
ATC
zuclopenthixol; systemic
10.7
69.3
137
131
N05AA02
ATC
levomepromazine; systemic
3.7
68.2
323
925
N03AG01
ATC
valproic acid; systemic, rectal
3.2
67.0
378
1238
307
Kela drug reimbursment
Tacrine, donepezil, rivastigmine, galantamine and other major and expensive drugs used to treat Alzheimer's disease
2.7
65.3
474
1834
AEA00
NOMESCO Finland
Replacement of impulse generator of stimulation device in the nervous system
20.3
64.9
98
49
R4130
NOMESCO Finland
Speech therapy
5.0
64.9
217
446
N05AC02
ATC
thioridazine; oral
5.8
64.5
190
337
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
2.8
64.0
454
1731
SPAT1215
SPAT
Assessment of need for medical rehabilitation
3.3
62.8
333
1041
SPAT1224
SPAT
Implementation of speech therapy rehabilitation plan
6.4
62.7
172
278
G02CB01
ATC
bromocriptine; systemic
10.3
62.6
126
125
G21.8
ICD-10 Finland
Other secondary parkinsonism
48.1
62.5
76
16
SPAT1234
SPAT
Support of social functional capacity
2.8
62.3
432
1622
29599
ICD-8 Finland
Schizophrenia, Unspecified type
14.2
61.4
106
76
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.9
61.2
1148
6845
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.0
60.9
898
4897
P72
ICPC
Schizophrenia
7.7
59.6
142
188
N06AB10
ATC
escitalopram; oral
2.0
57.2
806
4307
N05AA01
ATC
chlorpromazine; systemic, rectal
7.4
56.4
138
190
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
2.5
56.3
479
2023
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.9
55.8
1009
5916
F02.30
ICD-10 Finland
Dementia in Parkinson's disease without additional symptoms
553.7
55.7
55
*
N29
ICPC
Neurological sympt/complt other
4.7
54.8
195
428
R1250
NOMESCO Finland
Evaluation of functional capability
4.9
54.8
186
389
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.9
54.2
881
4967
G31.8
ICD-10 Finland
Other specified degenerative diseases of nervous system
11.4
53.0
101
90
N05AX12
ATC
aripiprazole; systemic
5.7
52.3
155
277
N05AB03
ATC
perphenazine; systemic, rectal
3.7
52.0
240
672
N19
ICPC
Speech disorder
5.9
51.3
148
256
D21
ICPC
Swallowing problem
5.4
50.7
157
296
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.6
50.4
1588
10976
29580
ICD-8 Finland
Schizophrenia, Other
12.0
50.0
93
79
N28
ICPC
Limited function/disability (N)
4.8
50.0
172
365
N39.4
ICD-10 Finland
Other specified urinary incontinence
2.3
49.9
514
2387
F20.30
ICD-10 Finland
Undifferentiated schizophrenia continuous
9.9
49.3
101
104
N05BA06
ATC
lorazepam; systemic, sublingual
2.6
48.6
381
1534
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
2.5
47.9
390
1605
R26.8
ICD-10 Finland
Other and unspecified abnormalities of gait and mobility
4.0
47.7
199
510
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
2.1
47.4
575
2874
N06AB04
ATC
citalopram; systemic
1.7
46.7
1077
6787
SPAT1231
SPAT
Assessment of adjustments needed in living environment
3.6
46.3
221
636
N04AA01
ATC
trihexyphenidyl; oral
100.9
45.8
50
5
SPAT1137
SPAT
Taking care of patient’s/customer’s hygiene
2.3
45.7
479
2240
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.8
44.6
313
1179
ZXM20
NOMESCO Finland
Intraoperative use of computerised tomography
9.9
43.7
89
91
SPAT1226
SPAT
Implementation of occupational therapy rehabilitation plan
3.2
42.6
238
772
G90.3
ICD-10 Finland
Multi-system degeneration
46.8
41.9
51
11
G25.8
ICD-10 Finland
Other specified extrapyramidal and movement disorders
3.7
41.6
187
512
N05AN01
ATC
lithium; oral
4.7
41.6
146
317
R47.1
ICD-10 Finland
Dysarthria and anarthria
6.6
41.6
109
167
F20.5
ICD-10 Finland
Residual schizophrenia
10.7
41.3
81
77
N30.0
ICD-10 Finland
Acute cystitis
1.9
41.2
721
4137
J69.0
ICD-10 Finland
Pneumonitis due to food and vomit
3.6
41.1
191
538
G23.8
ICD-10 Finland
Other specified degenerative diseases of basal ganglia
77.4
40.9
46
6
U04
ICPC
Incontinence urine
2.5
40.9
331
1356
S01.0
ICD-10 Finland
Open wound of scalp
2.1
40.7
479
2357
A04
ICPC
Weakness/tiredness general
1.8
39.1
711
4124
SPAT1295
SPAT
Other function in accordance with physical therapy nomenclature
2.4
38.5
351
1529
N03AX12
ATC
gabapentin; oral
1.8
38.4
774
4646
F02.32
ICD-10 Finland
Dementia in Parkinson's disease other additional symptoms, mainly hallucinations
380.1
38.1
38
*
29530
ICD-8 Finland
Schizophrenia, Paranoid type
11.4
38.1
72
64
29570
ICD-8 Finland
Schizophrenia, Schizo-affective type
15.8
37.3
61
39
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.7
36.5
791
4849
R35
ICD-10 Finland
Polyuria
2.1
36.3
426
2089
K59.0
ICD-10 Finland
Constipation
2.3
36.0
369
1702
N99
ICPC
Neurological disease other
5.3
35.3
110
210
R13
ICD-10 Finland
Dysphagia
2.2
35.0
393
1891
K59.09
ICD-10 Finland
Constipation, unspecified
2.1
34.9
404
1970
AA5QN
NOMESCO Finland
NA
124.2
34.7
37
*
188
Kela drug reimbursment
Psychosis requiring demanding treatment
7.3
34.4
84
117
F20
ICD-10 Finland
Schizophrenia
10.4
34.0
67
65
2959E
ICD-9 Finland
Schizophrenic psychoses, Unspecified schizophrenia[ERILAISTUMATON SKITSOFRENIA,KROONINEN AKUUTTI VAIHE]
15.3
33.8
56
37
Z2445
NOMESCO Finland
Psychologist
3.4
33.8
171
517
F25.9
ICD-10 Finland
Schizoaffective disorder, unspecified
7.5
33.4
80
108
G21.1
ICD-10 Finland
Other drug-induced secondary parkinsonism
15.6
32.9
54
35
S72.0
ICD-10 Finland
Fracture of neck of femur
2.3
32.8
314
1402
N05BA01
ATC
diazepam; systemic, rectal
1.7
32.8
694
4214
SPAT1297
SPAT
Other function in accordance with speech therapy nomenclature
10.0
32.7
66
67
R60.0
ICD-10 Finland
Localized oedema
1.8
32.3
653
3908
130
Kela drug reimbursment
Malignant tumour
0.4
31.2
126
3118
SPAT1245
SPAT
Provision of support and information to patient’s family members
2.2
30.8
331
1560
N04BX04
ATC
opicapone; oral
+∞
30.2
29
*
P20
ICPC
Memory disturbance
1.6
30.2
823
5363
29510
ICD-8 Finland
Schizophrenia, Hebephrenic type
12.4
29.9
54
44
M48.0
ICD-10 Finland
Spinal stenosis
1.7
29.3
740
4718
N08
ICPC
Abnormal involuntary movements
14.0
29.3
50
36
N04BC07
ATC
apomorphine; parenteral
+∞
29.2
28
*
34200
ICD-8 Finland
Paralysis agitans, Parkinsonismus
+∞
29.2
28
*
F20.10
ICD-10 Finland
Raise schizophrenia continuously
13.2
29.1
51
39
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
3.3
29.0
153
478
2959C
ICD-9 Finland
Schizophrenic psychoses, Unspecified schizophrenia[ERILAISTUMATON SKITSOFRENIA,KROONINEN]
11.1
28.9
55
50
F20.0
ICD-10 Finland
Paranoid schizophrenia
8.1
28.7
65
81
G04BD08
ATC
solifenacin; oral
1.9
28.5
425
2288
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
2.6
28.4
210
818
N04BC01
ATC
bromocriptine; oral
48.8
28.4
34
7
M54.5
ICD-10 Finland
Low back pain
1.5
28.1
1342
9949
W19
ICD-10 Finland
Unspecified fall
1.8
27.7
500
2880
YX8AD
NOMESCO Finland
Stereotactic CT examination for dose design of radiotherapy
35.2
27.4
35
10
P29
ICPC
Psychological sympt/compl other
2.8
27.4
184
677
L03
ICPC
Low back symptom/complaint
1.5
27.3
1013
7103
F0232, G20
ICD-10 Finland
NA
+∞
27.1
26
*
F0230, G20
ICD-10 Finland
NA
+∞
27.1
26
*
G91.2
ICD-10 Finland
Normal-pressure hydrocephalus
3.5
26.5
129
380
R41.0
ICD-10 Finland
Disorientation, unspecified
2.4
26.1
230
984
2953E
ICD-9 Finland
Schizophrenic psychoses, Paranoid type[PARANOIDISTYYPPINEN SKITSOFRENIA,KROONINEN AKUUTTI]
13.5
24.9
43
32
SPAT1240
SPAT
Therapeutic discussion
2.0
24.8
321
1636
N05CD07
ATC
temazepam; oral
1.6
24.7
779
5242
JDB10
NOMESCO Finland
Percutaneous gastrostomy
3.9
24.7
103
267
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
1.9
24.4
407
2279
NFB20
NOMESCO Finland
Primary partial prosthetic replacement of hip joint using cement, other or unspecified
2.5
24.3
192
778
N06AX21
ATC
duloxetine; oral
1.8
23.9
399
2234
R1260
NOMESCO Finland
Evaluation of communicative skills
3.2
23.7
128
408
SPAT1221
SPAT
Guidance concerning rehabilitation services and livelihood
3.4
23.7
115
339
Z75.5
ICD-10 Finland
Holiday relief care
4.0
23.6
96
244
J01EA01
ATC
trimethoprim; systemic
1.4
23.3
1182
8812
S06.0
ICD-10 Finland
Concussion
1.7
23.2
472
2816
SPAT1254
SPAT
Administration of medicine
1.5
23.1
794
5448
N06AX03
ATC
mianserin; oral
2.1
23.0
259
1245
N02BE01
ATC
paracetamol; systemic, rectal
1.4
22.6
4201
38715
N05AD01
ATC
haloperidol; systemic
2.3
22.5
205
894
F25.00
ICD-10 Finland
Schizoaffective syndrome, manic type with only simultaneous bipolar and schizophrenic symptoms
7.4
22.3
53
72
SPAT1301
SPAT
No procedures
1.4
22.3
1571
12413
SPAT1053
SPAT
Memory test
1.5
22.3
990
7182
R42
ICD-10 Finland
Dizziness and giddiness
1.4
22.2
1129
8411
F29
ICD-10 Finland
Unspecified nonorganic psychosis
3.1
22.2
122
395
29560
ICD-8 Finland
Residual schizophrenia
18.0
22.1
34
19
N04BX01
ATC
tolcapone; oral
+∞
21.9
21
*
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.8
21.6
388
2225
R55
ICD-10 Finland
Syncope and collapse
1.6
21.5
621
4080
K02.1
ICD-10 Finland
Caries of dentine
1.3
21.4
2073
17204
A06AC01
ATC
ispaghula (psylla seeds); oral
1.4
21.4
1205
9142
R2110
NOMESCO Finland
Giving the first information
2.0
21.0
284
1473
R32
ICD-10 Finland
Unspecified urinary incontinence
2.5
20.8
172
711
N31.9
ICD-10 Finland
Neuromuscular dysfunction of bladder, unspecified
4.5
20.6
74
168
AAW01
NOMESCO Finland
Implantation of intracranial stimulation device
110.4
20.6
22
*
F20.1
ICD-10 Finland
Hebephrenic schizophrenia
25.6
20.4
28
11
N03AX09
ATC
lamotrigine; oral
2.7
20.4
143
543
R60.9
ICD-10 Finland
Oedema, unspecified
2.0
20.3
257
1297
2959A
ICD-9 Finland
Schizophrenic psychoses, Unspecified schizophrenia[ERILAISTUMATON SKITSOFRENIA,TARKEMMIN MÄÄRITTELEMÄT]
10.6
20.3
39
37
G04BD04
ATC
oxybutynin; oral, transdermal
1.8
20.2
331
1842
KCV12
NOMESCO Finland
Urinary bladder endoscopic botulin therapy
4.5
20.1
72
163
R23
ICPC
Voice symptom/complaint
3.3
20.1
101
307
XKD06
NOMESCO Finland
Physiologic investigation of micturition
2.3
19.9
192
860
F20.09
ICD-10 Finland
Paranoid schizophrenia UNS
5.7
19.8
57
101
29500
ICD-8 Finland
Schizophrenia, Simple type
13.1
19.6
34
26
H02AB02
ATC
dexamethasone; systemic
0.5
19.6
156
3050
2957A
ICD-9 Finland
Schizophrenic psychoses, Schizo-affective type
8.2
19.4
43
53
S70.0
ICD-10 Finland
Contusion of hip
2.1
19.3
211
1004
C03CA01
ATC
furosemide; systemic
1.3
19.2
1851
15276
N06AX16
ATC
venlafaxine; oral
1.7
19.2
433
2662
F31.9
ICD-10 Finland
Bipolar affective disorder, unspecified
3.3
18.8
94
285
SPAT1296
SPAT
Other function in accordance with occupational therapy nomenclature
3.3
18.6
94
287
NA3AD
NOMESCO Finland
Lumbar spine and sacrum CT examination
2.5
18.6
153
635
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
1.8
18.6
342
1978
G23.2
ICD-10 Finland
Multiple system atrophy, parkinsonian type [MSA-P]
100.4
18.6
20
*
F25.01
ICD-10 Finland
Schizoaffective syndrome, manic type with prolonged schizophrenic than bipolar symptoms
12.3
18.5
33
27
H50.52
ICD-10 Finland
Exophoria
5.3
18.5
56
106
G04BD11
ATC
fesoterodine; oral
2.2
18.3
187
865
R44.1
ICD-10 Finland
Visual hallucinations
6.1
18.1
49
81
N86
ICPC
Multiple sclerosis
6.3
17.8
47
75
F31.0
ICD-10 Finland
Bipolar affective disorder, current episode hypomanic
4.6
17.8
62
137
C01CA01
ATC
etilefrine; systemic
4.1
17.8
70
174
A03FA01
ATC
metoclopramide; systemic, rectal
0.7
17.8
478
6924
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
1.6
17.8
483
3120
F02.31
ICD-10 Finland
Dementia in Parkinson's disease other additional symptoms, mainly paranoidism
+∞
17.7
17
*
F02.34
ICD-10 Finland
Dementia in Parkinson's disease, other additional symptoms of mixed type
+∞
17.7
17
*
F31.7
ICD-10 Finland
Bipolar affective disorder, currently in remission
3.5
17.6
81
231
2989X
ICD-9 Finland
Other nonorganic psychoses, Unspecified psychosis
5.5
17.4
51
93
XKD00
NOMESCO Finland
Uroflowmetry
1.4
17.4
999
7564
P99
ICPC
Psychological disorders other
3.2
17.4
91
286
SPAT1235
SPAT
Mental health, emotional support
7.0
17.3
42
60
G24.9
ICD-10 Finland
Dystonia, unspecified
7.5
17.1
40
54
29999
ICD-8 Finland
Unspecified psychosis
6.9
17.1
42
61
F20.39
ICD-10 Finland
Undifferentiated schizophrenia UNS
9.8
17.1
34
35
J01CA08
ATC
pivmecillinam; oral
1.3
17.0
1450
11699
F20.3
ICD-10 Finland
Undifferentiated schizophrenia
8.6
16.9
36
42
M03BX01
ATC
baclofen; systemic
3.2
16.9
89
282
F02.3
ICD-10 Finland
Dementia in Parkinson disease
+∞
16.7
16
*
TAB00
NOMESCO Finland
Lumbar puncture
2.2
16.6
177
834
G04BD07
ATC
tolterodine; oral
1.8
16.6
297
1701
I95.9
ICD-10 Finland
Hypotension, unspecified
2.9
16.5
102
359
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
2.1
16.4
188
913
IGY02
SPAT
NA
10.7
16.4
31
29
2951C
ICD-9 Finland
Schizophrenic psychoses, Disorganised type[HEBEFREENISTYYPPINEN SKITSOFRENIA,KROONINEN]
12.1
16.3
29
24
G04BD09
ATC
trospium; oral
2.3
16.3
155
695
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.6
16.2
403
2544
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
1.4
16.2
784
5751
M04AA01
ATC
allopurinol; systemic
0.7
16.1
402
5916
SPAT1305
SPAT
Counselling and guidance related to physical exercise
1.6
16.1
464
3042
G04CA02
ATC
tamsulosin; oral
1.3
16.1
1485
12109
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
0.3
16.0
36
1150
T36
ICD-10 Finland
Poisoning by systemic antibiotics
2.3
16.0
142
615
F20.04
ICD-10 Finland
Paranoid schizophrenia with partial recurrence
6.6
15.8
40
61
F06.0
ICD-10 Finland
Organic hallucinosis
8.3
15.7
34
41
EBA00
NOMESCO Finland
Extraction of tooth
1.3
15.7
1289
10321
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.6
15.7
438
2850
L84
ICD-10 Finland
Corns and callosities
2.1
15.6
172
822
SPAT1244
SPAT
Occupational therapy
3.4
15.5
75
224
2953C
ICD-9 Finland
Schizophrenic psychoses, Paranoid type[PARANOIDISTYYPPINEN SKITSOFRENIA,KROONINEN]
10.0
15.4
30
30
F05.9
ICD-10 Finland
Delirium, unspecified
2.4
15.4
134
573
AAF05
NOMESCO Finland
Ventriculoperitoneal shunt
3.0
15.4
86
285
Z29
ICPC
Social problem NOS
2.9
15.3
95
336
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
2.8
15.2
95
338
K11.72
ICD-10 Finland
Xerostomia
20.1
15.1
22
11
SPAT1167
SPAT
Insertion of urinary catheter
1.9
15.0
216
1151
N30.9
ICD-10 Finland
Cystitis, unspecified
1.8
14.9
270
1554
SFC01
NOMESCO Finland
Adjuvant procedure of filling therapy
1.4
14.9
959
7386
K08.3
ICD-10 Finland
Retained dental root
1.7
14.8
323
1965
F20.34
ICD-10 Finland
Undifferentiated schizophrenia with partial recurrence
14.2
14.5
24
17
L17
ICPC
Foot/toe symptom/complaint
1.3
14.5
1086
8560
AA1BM
NOMESCO Finland
MRI examination of brain with 3 Tesla magnet
3.8
14.5
60
158
Z76.8
ICD-10 Finland
Persons encountering health services in other specified circumstances
2.2
14.4
141
639
Z02.4
ICD-10 Finland
Examination for driving licence
0.7
14.3
844
10774
L89
ICD-10 Finland
Decubitus ulcer and pressure area
2.5
14.2
112
458
R5110
SPAT
NA
2.2
14.2
140
639
SPAT1050
SPAT
Extensive neurological examination
2.4
14.0
120
513
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
1.4
13.7
685
5039
M54.4
ICD-10 Finland
Lumbago with sciatica
1.4
13.6
588
4209
F023, G20
ICD-10 Finland
NA
+∞
13.5
13
*
F0234, G20
ICD-10 Finland
NA
+∞
13.5
13
*
M41.9
ICD-10 Finland
Scoliosis, unspecified
3.3
13.5
66
199
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
1.9
13.5
188
990
F25.10
ICD-10 Finland
Schizoaffective syndrome, depressive type with only concomitant bipolar and schizophrenic symptoms
6.6
13.5
34
52
29540
ICD-8 Finland
Acute schizophrenia episode
8.3
13.5
29
35
Z02.7
ICD-10 Finland
Issue of medical certificate
1.7
13.4
262
1546
F25.20
ICD-10 Finland
Schizoaffective syndrome, mixed type with only concomitant bipolar and schizophrenic symptoms
6.4
13.3
34
53
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.4
13.3
748
5622
K59.00
ICD-10 Finland
Constipation caused by slow bowel passage (SCT)
2.4
13.3
109
456
H02AB06
ATC
prednisolone; systemic
0.8
13.2
1605
18752
E86
ICD-10 Finland
Volume depletion
2.1
13.2
150
730
Z50.5
ICD-10 Finland
Speech therapy
3.3
13.2
64
193
H50.31
ICD-10 Finland
Intermittent exotropia
5.0
13.0
41
83
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.3
12.9
1936
16684
UKC02
NOMESCO Finland
Cystoscopy
1.3
12.9
918
7164
F20.19
ICD-10 Finland
Hebefren schizophrenia UNS
11.5
12.8
23
20
F25.2
ICD-10 Finland
Schizoaffective disorder, mixed type
9.7
12.7
25
26
WF049
NOMESCO Finland
Radiotherapy of metastasis
0.3
12.6
30
929
F20.8
ICD-10 Finland
Other schizophrenia
7.8
12.6
28
36
S22.3
ICD-10 Finland
Fracture of rib
1.6
12.5
295
1838
WX290
NOMESCO Finland
Other blockade of nerve
1.3
12.4
1310
10801
R33
ICD-10 Finland
Retention of urine
1.5
12.4
482
3376
F25
ICD-10 Finland
Schizoaffective disorders
13.2
12.4
21
16
A29
ICPC
General symptom/complaint other
1.5
12.4
509
3607
RF120
NOMESCO Finland
NA
3.0
12.3
68
225
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.2
12.3
1877
16184
Z50.1
ICD-10 Finland
Other physical therapy
1.7
12.3
250
1494
F25.21
ICD-10 Finland
Schizoaffective syndrome, mixed type with prolonged schizophrenic than bipolar symptoms
8.0
12.3
27
34
IGY99
SPAT
NA
10.5
12.2
23
22
XXA00
NOMESCO Finland
Clinical examination requiring general anaesthesia
4.4
12.1
43
99
ZXE13
NOMESCO Finland
Procedure duration 90 to 119 minutes
2.4
12.1
101
425
N40
ICD-10 Finland
Hyperplasia of prostate
1.3
12.1
1368
11373
R4110
SPAT
NA
2.1
12.1
128
605
EBA30
NOMESCO Finland
Excision of root of tooth
1.7
12.0
244
1457
SCA02
NOMESCO Finland
Analysis and advice of nutrition with regard to dentistry
1.6
12.0
295
1855
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
2.5
12.0
95
391
F20.02
ICD-10 Finland
Paranoid schizophrenia stable periodically
11.0
12.0
22
20
Z01.8
ICD-10 Finland
Other specified special examinations
1.3
12.0
888
6968
SAA02
NOMESCO Finland
Basic examination of mouth
1.2
11.9
2267
20008
S00.0
ICD-10 Finland
Superficial injury of scalp
2.3
11.8
108
479
S01.1
ICD-10 Finland
Open wound of eyelid and periocular area
2.2
11.7
119
553
G25.1
ICD-10 Finland
Drug-induced tremor
8.9
11.7
24
27
F31.20
ICD-10 Finland
Bipolar disorder, manic episode with mood-congruent psychotic symptoms
4.3
11.7
42
98
S01.8
ICD-10 Finland
Open wound of other parts of head
2.8
11.6
73
264
S32.0
ICD-10 Finland
Fracture of lumbar vertebra
1.9
11.6
166
887
N87
ICD-10 Finland
Dysplasia of cervix uteri
22.9
11.6
16
7
UDQ42
NOMESCO Finland
Endoscopic assessment of swallowing function
8.1
11.5
25
31
N05AL01
ATC
sulpiride; systemic
2.5
11.5
85
337
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
0.3
11.5
29
872
AAG99
NOMESCO Finland
Other stereotactic intracranial operation
+∞
11.5
11
*
C10AA07
ATC
rosuvastatin; oral
0.8
11.3
740
9352
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
0.4
11.3
41
1054
AA1AA
NOMESCO Finland
Head X-ray examination
3.1
11.3
60
195
AA1BD
NOMESCO Finland
Extensive CT of head and brain
2.0
11.2
133
659
N04AB02
ATC
orphenadrine (chloride); systemic
25.0
11.1
15
6
NA1AD
NOMESCO Finland
Cervical spine CT examination
1.8
11.1
174
958
H01BA02
ATC
desmopressin; nasal, systemic, sublingual
2.6
11.1
78
301
R29.6
ICD-10 Finland
Tendency to fall, not elsewhere classified
5.0
11.0
34
68
Z11
ICPC
Compliance/being ill problem
3.9
11.0
44
114
R63.4
ICD-10 Finland
Abnormal weight loss
1.9
11.0
169
924
N03AF02
ATC
oxcarbazepine; oral
2.1
11.0
125
612
29520
ICD-8 Finland
Schizophrenia, Catatonic type
13.9
10.9
18
13
N06AB06
ATC
sertraline; oral
1.5
10.9
326
2155
TAW99
NOMESCO Finland
Other minor neurosurgical procedure
4.8
10.8
35
74
D12
ICPC
Constipation
1.8
10.8
175
974
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.3
10.8
694
5323
NA7EA
NOMESCO Finland
Scoliosis X-ray examination
2.7
10.8
72
270
ABC36
NOMESCO Finland
Decompression of lumbar nerve roots
1.7
10.7
244
1505
M54.9
ICD-10 Finland
Dorsalgia, unspecified
1.5
10.7
401
2787
JX1LA
NOMESCO Finland
Kinetic X-ray of alimentary tract with pictures
12.9
10.6
18
14
N05AB02
ATC
fluphenazine; systemic
3.6
10.6
46
128
TKC10
NOMESCO Finland
Percutaneous puncture of bladder
2.3
10.6
92
398
M79.6
ICD-10 Finland
Pain in limb
1.2
10.5
1440
12212
E9509
ICD-8 Finland
Suicide and self-inflicted poisoning by solid or liquid substances, Other and unspecified solid and liquid substances
3.9
10.5
42
109
G72.8
ICD-10 Finland
Other specified myopathies
2.3
10.5
94
414
P98
ICPC
Psychosis NOS/other
6.5
10.5
26
40
SPAT1243
SPAT
Psychiatric/psychological examination
2.9
10.4
62
217
AA400
NOMESCO Finland
Electroconvulsive therapy
4.3
10.4
37
86
SPAT1101
SPAT
Orthostatic test
1.6
10.3
247
1547
SPAT1263
SPAT
Sampling
1.2
10.3
1838
16038
G81.9
ICD-10 Finland
Hemiplegia, unspecified
3.0
10.3
56
186
F22.0
ICD-10 Finland
Delusional disorder
2.5
10.2
76
302
SPAT1262
SPAT
Handing over of treatment supplies
1.3
10.2
893
7158
R1230
NOMESCO Finland
Neuropsychological evaluation of need and possibilities to rehabilitation
4.1
10.2
38
93
P01
ICPC
Feeling anxious/nervous/tense
1.7
10.2
186
1079
N05AE04
ATC
ziprasidone; systemic
7.4
10.2
23
31
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
1.4
10.1
471
3419
S00.9
ICD-10 Finland
Superficial injury of head, part unspecified
3.0
10.1
56
188
G40.9
ICD-10 Finland
Epilepsy, unspecified
1.9
10.0
147
791
N05AD03
ATC
melperone; systemic
2.3
10.0
90
395
R44.3
ICD-10 Finland
Hallucinations, unspecified
4.1
10.0
37
90
N03AF01
ATC
carbamazepine; oral, rectal
1.6
10.0
235
1464
G21.2
ICD-10 Finland
Secondary parkinsonism due to other external agents
40.1
10.0
12
*
RF420
NOMESCO Finland
NA
2.6
9.9
68
260
S01.9
ICD-10 Finland
Open wound of head, part unspecified
2.4
9.9
84
359
M41.4
ICD-10 Finland
Neuromuscular scoliosis
16.7
9.9
15
9
R30.1
ICD-10 Finland
Vesical tenesmus
2.3
9.8
89
394
SPAT1294
SPAT
Other function in accordance with health social work nomenclature
2.0
9.8
118
589
359
Kela drug reimbursment
Mirabegroni
3.4
9.8
45
132
ICB03
SPAT
NA
9.5
9.7
19
20
2956C
ICD-9 Finland
Schizophrenic psychoses, Residual schizophrenia[RESIDUAALINEN SKITSOFRENIA,KROONINEN]
9.5
9.7
19
20
S20.2
ICD-10 Finland
Contusion of thorax
1.7
9.6
195
1164
IFA99
SPAT
NA
55.1
9.6
11
*
G04CB01
ATC
finasteride; oral (testosterone-5-alpha reductase inhibitors)
1.3
9.6
694
5411
A06AX04
ATC
linaclotide; oral
6.8
9.6
23
34
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
1.4
9.6
424
3050
G21.0
ICD-10 Finland
Malignant neuroleptic syndrome
10.0
9.5
18
18
W06
ICD-10 Finland
Fall involving bed
3.0
9.5
52
174
L01BC06
ATC
capecitabine; oral
0.4
9.5
38
941
E950A
ICD-9 Finland
Suicide and self-inflicted poisoning by solid or liquid substances
3.3
9.4
46
142
N05AX13
ATC
paliperidone; systemic
7.5
9.4
21
28
SPAT1172
SPAT
Guidance concerning hydration
1.9
9.4
140
762
XKC03
NOMESCO Finland
Water cystometry
1.8
9.3
145
799
U05
ICPC
Urination problems other
1.6
9.3
222
1393
R25.8
ICD-10 Finland
Other and unspecified abnormal involuntary movements
6.4
9.2
23
36
Z3226
NOMESCO Finland
Physiotherapist
1.3
9.2
792
6332
F25.0
ICD-10 Finland
Schizoaffective disorder, manic type
7.3
9.2
21
29
G35
ICD-10 Finland
Multiple sclerosis
3.0
9.2
50
167
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
0.7
9.2
326
4514
Y94.0
ICD-10 Finland
Accident at home
2.1
9.2
95
448
G25
ICD-10 Finland
Other extrapyramidal and movement disorders
13.7
9.2
15
11
C10AX09
ATC
ezetimibe; oral
0.7
9.2
266
3814
N17
ICPC
Vertigo/dizziness
1.4
9.1
490
3644
F20.01
ICD-10 Finland
Paranoid schizophrenia periodically with gradual deterioration
7.7
9.1
20
26
WYA20
NOMESCO Finland
Home visit
2.1
9.1
97
463
S01.41
ICD-10 Finland
Open wound in the temple-jaw region
2.9
9.1
53
184
U07
ICPC
Urine symptom/complaint other
1.6
9.1
260
1705
K88
ICPC
Postural hypotension
2.8
9.1
54
191
P03
ICPC
Feeling depressed
1.7
9.1
193
1173
AXX01
NOMESCO Finland
Memory assessment
36.7
9.0
11
*
3339X
ICD-9 Finland
Other extrapyramidal disease and abnormal movement disorders, Other and unspecified extrapyramidal diseases and abnormal movement disorders
36.7
9.0
11
*
29820
ICD-8 Finland
Other psychoses, Reactive confusion
9.0
9.0
18
20
2962E
ICD-9 Finland
Affective psychoses, Major depressive disorder, single episode[PSYCH.BIPOLARIS MANICA,VAIKEA-ASTE,PSYKOOT PIIRTEIT]
9.0
9.0
18
20
SPAT1251
SPAT
Organisation of medication
1.7
9.0
184
1105
SFA30
NOMESCO Finland
Filling on tree or more surfaces of tooth
1.2
9.0
1438
12368
SPAT1260
SPAT
Consultation of another employee
1.3
8.9
757
6037
K03.66
ICD-10 Finland
Tooth plaque
1.6
8.9
226
1436
L29
ICPC
Musculoskeletal sympt/complt other
1.5
8.9
296
2005
M80.9
ICD-10 Finland
Unspecified osteoporosis with pathological fracture
2.0
8.9
105
523
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
1.5
8.9
266
1764
N03AA03
ATC
primidone; oral
6.1
8.9
23
38
N05AF01
ATC
flupentixol; systemic
2.4
8.9
74
315
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
1.7
8.8
160
929
SPAT1292
SPAT
Other function in accordance with SHToL (Finnish classification of nursing interventions)
1.4
8.8
426
3111
M80.0
ICD-10 Finland
Postmenopausal osteoporosis with pathological fracture
2.1
8.8
97
470
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
2.5
8.8
67
272
K07
ICPC
Swollen ankles/oedema
1.6
8.7
221
1408
N31.1
ICD-10 Finland
Reflex neuropathic bladder, not elsewhere classified
3.5
8.7
38
108
A08
ICPC
Swelling
1.6
8.7
196
1213
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
1.6
8.6
210
1322
G24.8
ICD-10 Finland
Other dystonia
6.6
8.6
21
32
N02CA01
ATC
dihydroergotamine; nasal, systemic
4.2
8.5
31
75
IGY02
NOMESCO Finland
Psychiatric monitoring contact
2.9
8.5
50
175
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
1.7
8.5
162
953
F20.08
ICD-10 Finland
Paranoid schizophrenia other definite
9.0
8.5
17
19
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.3
8.5
608
4734
N03AX16
ATC
pregabalin; oral
1.3
8.5
943
7782
Z60.8
ICD-10 Finland
Other problems related to social environment
4.9
8.5
26
53
N05AE02
ATC
molindone; oral
27.5
8.5
11
*
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
1.5
8.4
241
1581
F32.3
ICD-10 Finland
Severe depressive episode with psychotic symptoms
2.4
8.4
69
293
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
1.3
8.4
578
4474
G22
ICD-10 Finland
Parkinsonism in diseases classified elsewhere
90.2
8.4
9
*
97010
ICD-8 Finland
Adverse effect of psychotherapeutics, Tranquillisers
4.3
8.4
29
67
C34.1
ICD-10 Finland
Malignant neoplasm: Upper lobe, bronchus or lung
0.2
8.4
11
461
NAG63
NOMESCO Finland
Posterior fusion of lumbar spine with fixation, more than 3 vertebraea
3.1
8.3
43
139
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
1.5
8.3
268
1808
SCA03
NOMESCO Finland
Preventive oral health care, extensive
1.8
8.3
131
728
S22.0
ICD-10 Finland
Fracture of thoracic vertebra
2.1
8.3
91
441
IAB01
NOMESCO Finland
Psychiatric pharmacotherapy consultation
5.2
8.3
24
46
N06CA01
ATC
amitriptyline and psycholeptics; systemic
1.4
8.3
398
2907
SCA01
NOMESCO Finland
Simple analysis and advice of nutrition with regard to dentistry
1.3
8.2
805
6539
2954A
ICD-9 Finland
Schizophrenic psychoses, Acute schizophrenic episode
7.1
8.2
19
27
F06.2
ICD-10 Finland
Organic delusional [schizophrenia-like] disorder
7.1
8.2
19
27
L21.9
ICD-10 Finland
Seborrhoeic dermatitis, unspecified
2.2
8.2
81
375
2956E
ICD-9 Finland
Schizophrenic psychoses, Residual schizophrenia[RESIDUAALINEN SKITSOFRENIA,KROONINEN AKUUTTI VAIHE]
11.7
8.1
14
12
N05AE03
ATC
sertindole; oral
10.0
8.0
15
15
N04AC01
ATC
benzatropine; systemic
22.0
8.0
11
5
AAF20
NOMESCO Finland
Revision of shunt of ventricle of brain
3.8
8.0
32
85
NA3EA
NOMESCO Finland
Lumbar spine X-ray examination with flexion
1.8
8.0
125
694
IAA01
NOMESCO Finland
Assessment of need for psychiatric treatment
2.8
8.0
48
172
B03BA03
ATC
hydroxocobalamin; parenteral
1.5
8.0
303
2115
N06AX26
ATC
vortioxetine; oral
1.8
8.0
139
797
9691A
ICD-9 Finland
Poisoning by psychotropic agents, Phenothiazine-based tranquillisers
5.9
8.0
21
36
ZYC01
NOMESCO Finland
Remote contact by phone
1.7
8.0
146
849
S20
ICPC
Corn/callosity
2.0
7.9
95
476
F31.30
ICD-10 Finland
Bipolar disorder Depressive episode without somatic syndrome
2.8
7.9
48
173
A01
ICPC
Pain general/multiple sites
1.5
7.9
302
2111
R07.4
ICD-10 Finland
Chest pain, unspecified
1.2
7.9
1221
10438
F03
ICD-10 Finland
Unspecified dementia
1.5
7.9
256
1731
F31.1
ICD-10 Finland
Bipolar affective disorder, current episode manic without psychotic symptoms
3.3
7.9
37
112
SPAT1304
SPAT
Counselling and guidance related to ageing
1.4
7.9
383
2802
SPAT1252
SPAT
Overall medication plan or its review
1.4
7.9
342
2451
F25.1
ICD-10 Finland
Schizoaffective disorder, depressive type
7.7
7.9
17
22
WF002
NOMESCO Finland
Radical radiotherapy
0.6
7.9
92
1608
NE1AD
NOMESCO Finland
Pelvis and hip bones CT examination
2.0
7.8
95
481
F31.6
ICD-10 Finland
Bipolar affective disorder, current episode mixed
3.4
7.8
35
102
I87.2
ICD-10 Finland
Venous insufficiency (chronic)(peripheral)
1.4
7.8
399
2948
RF433
NOMESCO Finland
NA
9.4
7.8
15
16
WX110
NOMESCO Finland
Local anesthesy
1.2
7.7
2690
24741
G23.3
ICD-10 Finland
Multiple system atrophy, cerebellar type [MSA-C]
45.0
7.7
9
*
N06DA02
ATC
donepezil; oral
1.4
7.7
319
2266
F05.0
ICD-10 Finland
Delirium not superimposed on dementia, so described
4.6
7.7
25
55
29630
ICD-8 Finland
Affective psychoses, Manic-depressive psychosis, circular type
7.4
7.7
17
23
29610
ICD-8 Finland
Affective psychoses, Manic-depression psychosis, manic type
7.4
7.7
17
23
D38.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Trachea, bronchus and lung
0.5
7.6
43
934
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
1.6
7.6
174
1081
NA2BG
NOMESCO Finland
Thoracal spine MRI examination with high intensity magnet
2.1
7.6
77
362
EBA05
NOMESCO Finland
Complicated extraction of tooth
1.3
7.6
645
5141
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.2
7.6
1292
11149
JC2KB
NOMESCO Finland
Functional X-ray examination of swallowing
2.4
7.5
60
253
F05.8
ICD-10 Finland
Other delirium
2.9
7.5
43
148
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.2
7.5
1326
11488
S40.0
ICD-10 Finland
Contusion of shoulder and upper arm
1.7
7.4
136
795
SPAT1360
SPAT
Extensive global examination
1.4
7.4
337
2439
M40.1
ICD-10 Finland
Other secondary kyphosis
6.4
7.4
18
28
N32.82
ICD-10 Finland
Instability of the detrusor vesicae muscle
2.2
7.4
73
341
2951E
ICD-9 Finland
Schizophrenic psychoses, Disorganised type[HEBEFREENISTYYPPINEN SKITSOFRENIA,KROONINEN AKUUTTI]
13.4
7.4
12
9
N06AG02
ATC
moclobemide; oral
1.6
7.4
168
1046
R56.8
ICD-10 Finland
Other and unspecified convulsions
1.6
7.3
182
1154
S00.1
ICD-10 Finland
Contusion of eyelid and periocular area
2.2
7.3
72
334
SAB01
NOMESCO Finland
Restricted oral and dental health check by dental hygienist or dental assistant
1.5
7.3
243
1651
TKC22
NOMESCO Finland
Catheterisation instruction
1.8
7.3
111
610
H51.1
ICD-10 Finland
Convergence insufficiency and excess
8.4
7.3
15
18
AA5DR
NOMESCO Finland
Brain metabolism PET with CT
8.4
7.3
15
18
A03FA02
ATC
cisapride; oral, rectal
1.4
7.3
356
2610
N04C02
ATC
NA
+∞
7.3
7
*
KE1BE
NOMESCO Finland
Rectal ultrasound examinaiton of prostata
1.3
7.3
450
3428
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
0.4
7.3
30
730
SAA01
NOMESCO Finland
Simple examination of mouth
1.2
7.3
2558
23503
TJD20
NOMESCO Finland
Change of gastrostomy tube
3.7
7.2
29
78
K56.2
ICD-10 Finland
Volvulus
2.9
7.2
42
147
AA052
NOMESCO Finland
NA
15.7
7.2
11
7
R39.1
ICD-10 Finland
Other difficulties with micturition
1.7
7.2
141
838
SAD01
NOMESCO Finland
Assessment of need for oral health care, standard
1.4
7.2
352
2580
P73
ICPC
Affective psychosis
5.4
7.2
20
37
N02AA05
ATC
oxycodone; systemic
1.3
7.2
730
5950
M21.4
ICD-10 Finland
Flat foot [pes planus] (acquired)
1.9
7.2
94
491
31099
ICD-8 Finland
Borderline mental retardation, Other and unspecified
7.3
7.2
16
22
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
0.6
7.2
100
1671
N05AC04
ATC
pipotiazine; systemic
30.0
7.1
9
*
F2090
ICD-10 Finland
NA
30.0
7.1
9
*
G04CA52
ATC
tamsulosin and dutasteride; systemic
1.3
7.1
536
4204
N31.0
ICD-10 Finland
Uninhibited neuropathic bladder, not elsewhere classified
3.8
7.1
28
74
SFA20
NOMESCO Finland
Filling on two surfaces of tooth
1.2
7.1
1946
17502
WB113
NOMESCO Finland
Multiple adjuvant cytostatic therapy
0.5
7.1
40
872
F31
ICD-10 Finland
Bipolar affective disorder
3.4
7.1
32
95
L76
ICPC
Fracture: other
1.8
7.1
120
683
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
1.4
7.1
404
3038
F20.32
ICD-10 Finland
Undifferentiated schizophrenia stable periodically
12.0
7.1
12
10
SDA02
NOMESCO Finland
Parodonthologic therapy
1.2
7.1
1095
9352
G40.20
ICD-10 Finland
Complex partial seizures with only alteration of consciousness
2.5
7.1
50
198
N05CF01
ATC
zopiclone; oral
1.2
7.0
1527
13464
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
1.6
7.0
158
980
3AX01
NOMESCO Finland
NA
4.7
7.0
22
47
N31.8
ICD-10 Finland
Other neuromuscular dysfunction of bladder
3.4
7.0
31
91
ZY000
NOMESCO Finland
Hospital inpatient
3.4
7.0
31
91
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
1.5
7.0
200
1317
M20.4
ICD-10 Finland
Other hammer toe(s) (acquired)
1.6
7.0
172
1093
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
0.6
6.9
76
1349
G24.5
ICD-10 Finland
Blepharospasm
5.1
6.9
20
39
N05BE01
ATC
buspirone; oral
1.9
6.9
98
529
M43.1
ICD-10 Finland
Spondylolisthesis
1.7
6.9
140
845
S01
ICD-10 Finland
Open wound of head
2.3
6.9
61
271
ICB03
NOMESCO Finland
Psychiatric treatment plan, monitoring
2.9
6.9
38
131
30180
ICD-8 Finland
Personality disorders, Immatura
3.8
6.8
27
72
SAA03
NOMESCO Finland
Extended examination of mouth
1.2
6.8
1249
10841
J01MA02
ATC
ciprofloxacin; systemic
1.2
6.8
1817
16302
R21
NOMESCO Finland
Counselling and guidance in rehabilitation
2.6
6.8
45
173
G21
ICD-10 Finland
Secondary parkinsonism
40.1
6.8
8
*
RF432
NOMESCO Finland
NA
40.1
6.8
8
*
IBB01
SPAT
NA
40.1
6.8
8
*
Z73.6
ICD-10 Finland
Limitation of activities due to disability
2.6
6.7
46
180
M54
ICD-10 Finland
Dorsalgia
1.4
6.7
353
2621
SPAT1104
SPAT
Monitoring of emergency patient
1.4
6.7
292
2096
OAA80
SPAT
NA
0.2
6.7
7
333
RF410
NOMESCO Finland
NA
2.3
6.7
55
237
X59
ICD-10 Finland
Exposure to unspecified factor
1.3
6.7
683
5569
H53.2
ICD-10 Finland
Diplopia
1.7
6.7
129
765
L75
ICPC
Fracture: femur
2.1
6.7
70
336
IHZ05
SPAT
NA
3.5
6.7
29
84
F31.4
ICD-10 Finland
Bipolar affective disorder, current episode severe depression without psychotic symptoms
2.8
6.7
39
138
3321A
ICD-9 Finland
Parkinson's disease, Secondary Parkinsonism
22.5
6.7
9
*
N05BA12
ATC
alprazolam; oral
1.4
6.6
366
2741
G04CB02
ATC
dutasteride; oral
1.4
6.6
367
2750
XFP96
NOMESCO Finland
Other intraoperative electrophysiological investigation in arhythmia or disturbance of impulse propagation
1.8
6.6
107
603
K02
ICD-10 Finland
Dental caries
1.5
6.6
222
1515
M41.5
ICD-10 Finland
Other secondary scoliosis
4.6
6.6
21
46
WD405
NOMESCO Finland
Simple antiboidy therapy of methastized malignancy
0.3
6.5
16
483
WZA10
NOMESCO Finland
Long statement of health and health related matters
2.6
6.5
43
164
U02
ICPC
Urinary frequency/urgency
1.3
6.5
488
3823
F41.1
ICD-10 Finland
Generalized anxiety disorder
2.0
6.5
78
395
ZXE15
NOMESCO Finland
Procedure duration 120 to 149 minutes
2.4
6.5
51
215
K90
ICPC
Stroke/cerebrovascular accident
1.6
6.5
143
883
U07.1
ICD-10 Finland
Emergency use of U07.1 | COVID-19, virus identified
1.4
6.5
309
2257
R27.0
ICD-10 Finland
Ataxia, unspecified
3.5
6.5
28
81
A49.9
ICD-10 Finland
Bacterial infection, unspecified
1.3
6.5
534
4241
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.3
6.4
460
3581
N04AA03
ATC
metixene; oral
69.9
6.4
7
*
S72.1
ICD-10 Finland
Pertrochanteric fracture
1.7
6.4
123
730
L03AA02
ATC
filgrastim; parenteral
0.4
6.4
26
637
M10.9
ICD-10 Finland
Gout, unspecified
0.7
6.4
171
2484
G24.3
ICD-10 Finland
Spasmodic torticollis
2.8
6.3
37
131
F41.2
ICD-10 Finland
Mixed anxiety and depressive disorder
1.7
6.3
131
796
Z43.1
ICD-10 Finland
Attention to gastrostomy
6.5
6.3
15
23
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
0.7
6.3
170
2467
NE1AA
NOMESCO Finland
Pelvis X-ray examination
1.4
6.3
304
2223
A04AA02
ATC
granisetron; systemic, transdermal
0.6
6.3
96
1570
A02BC01
ATC
omeprazole; systemic
1.2
6.3
1244
10857
ZXY02
NOMESCO Finland
Neuropsychologist
4.2
6.3
22
53
R74
ICPC
Upper respiratory infection acute
0.8
6.3
450
5644
G91.9
ICD-10 Finland
Hydrocephalus, unspecified
3.6
6.3
26
73
F02.33
ICD-10 Finland
Dementia in Parkinson's disease other additional symptoms, mainly depression
+∞
6.2
6
*
2953D
ICD-9 Finland
Schizophrenic psychoses, Paranoid type[PARANOIDISTYYPPINEN SKITSOFRENIA,SUBKROON AKUUTTI]
26.7
6.2
8
*
F20.12
ICD-10 Finland
Hebefren schizophrenia stable periodically
26.7
6.2
8
*
F21
ICPC
NA
2.4
6.2
49
208
A46
ICD-10 Finland
Erysipelas
1.3
6.2
647
5291
K40.9
ICD-10 Finland
Unilateral or unspecified inguinal hernia, without obstruction or gangrene
1.3
6.2
647
5292
G62.9
ICD-10 Finland
Polyneuropathy, unspecified
1.5
6.1
168
1098
N31.2
ICD-10 Finland
Flaccid neuropathic bladder, not elsewhere classified
2.5
6.1
45
184
M47.9
ICD-10 Finland
Spondylosis, unspecified
1.6
6.1
137
850
R2
NOMESCO Finland
Guidance supporting rehabilitation
12.5
6.1
10
8
F99
ICD-10 Finland
Mental disorder, not otherwise specified
2.5
6.1
44
178
-1
NOMESCO Finland
NA
1.2
6.1
1018
8753
R26
ICD-10 Finland
Abnormalities of gait and mobility
3.8
6.1
23
60
P28
ICPC
Limited function/disability (P)
3.0
6.1
32
108
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.2
6.0
924
7869
SPAT1293
SPAT
Other function in accordance with rehabilitation guidance nomenclature
2.9
6.0
35
123
29830
ICD-8 Finland
Other psychoses, Acute paranoid reaction
4.4
6.0
20
46
SPAT1307
SPAT
Psychosocial counselling and guidance
1.8
6.0
102
586
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
0.3
6.0
16
468

Mortality – FinRegistry

Association

Association between endpoint G6_PARKINSON and mortality.

Females

Parameter HR [95% CI] p-value
G6_PARKINSON 2.269 [2.1, 2.45] < 0.001
Birth year 0.996 [0.99, 1.0] 0.325

During the follow-up period (1.1.1998 — 31.12.2019), 9442 out of 18382 females with G6_PARKINSON died.

Males

Parameter HR [95% CI] p-value
G6_PARKINSON 2.162 [1.96, 2.38] < 0.001
Birth year 0.988 [0.98, 1.0] 0.006

During the follow-up period (1.1.1998 — 31.12.2019), 11970 out of 22585 males with G6_PARKINSON died.

Mortality risk

Mortality risk for people of age

years, who have G6_PARKINSON.

N-year risk Females Males
1 0.163% 0.462%
5 1.349% 2.815%
10 3.481% 6.134%
15 6.402% 11.465%
20 11.11% 19.01%

Relationships between endpoints

Index endpoint: G6_PARKINSON – Parkinson's disease

GWS hits: 5

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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