Use of antiglaucoma preparations and miotics

H7_GLAUCOMAMEDICATION

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

None

473681

2. Check conditions

None

473681

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Medicine purchases: ATC S01EA

1 out of 7 registries used, show all original rules.

2864

4. Check minimum number of events

Min. number of events 3
2864

5. Include endpoints

None

2864

6. Filter based on genotype QC (FinnGen only)

2737

Control definitions (FinnGen only)

Control exclude
H7_GLAUCOMA

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 31315 19313 11757
Only index persons 26241 16426 9815
Unadjusted period prevalence (%)
Whole population 0.47 0.55 0.33
Only index persons 0.52 0.60 0.37
Median age at first event (years)
Whole population 71.87 73.07 69.86
Only index persons 70.67 71.97 68.49

-FinnGen-

Key figures

All Female Male
Number of individuals 2737 1468 1269
Unadjusted period prevalence (%) 0.60 0.58 0.64
Median age at first event (years) 67.66 67.08 68.34

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
2864
Matched controls
28638
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
S01ED02
ATC
betaxolol; ophthalmic
130.3
323.0
460
42
XCW99
NOMESCO Finland
Other investigative procedure of eye
7.9
323.0
944
1673
XCK10
NOMESCO Finland
Photography of fundus of eye
7.7
323.0
884
1571
S01EE05
ATC
tafluprost; ophthalmic
73.7
323.0
720
130
S01EA05
ATC
brimonidine; ophthalmic (sympathomimetics in glaucoma therapy)
9364.3
323.0
2574
32
S01EE01
ATC
latanoprost; ophthalmic
175.6
323.0
1941
338
WX140
NOMESCO Finland
Parabulbar anesthesy
19.6
323.0
763
521
114
Kela drug reimbursment
Glaucoma
881.0
323.0
2695
510
S01EC54
ATC
brinzolamide, combinations; ophthalmic
409.9
323.0
474
14
H40.5
ICD-10 Finland
Glaucoma secondary to other eye disorders
+∞
323.0
502
*
S01ED51
ATC
timolol, combinations; ophthalmic
403.7
323.0
2457
424
S01EC01
ATC
acetazolamide; systemic
138.0
323.0
1117
132
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
5.6
323.0
2013
8552
H40.10
ICD-10 Finland
Capsular glaucoma with pseudoexfoliation on the anterior lens capsule
1517.6
323.0
995
10
CHF05
NOMESCO Finland
Transscleral laser coagulation of ciliary body
+∞
323.0
343
*
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
4.8
323.0
1973
9005
H40.9
ICD-10 Finland
Glaucoma, unspecified
270.1
323.0
455
20
XCK00
NOMESCO Finland
Perimetry
40.2
323.0
1185
494
S01EA03
ATC
apraclonidine; ophthalmic
65.2
323.0
433
78
S01EC04
ATC
brinzolamide; ophthalmic
277.7
323.0
1455
106
H40.0
ICD-10 Finland
Glaucoma suspect
239.6
323.0
834
49
H40.13
ICD-10 Finland
Chronic glaucoma with open ventricular angle
1078.0
323.0
1541
30
S01EX03
ATC
NA
215.3
323.0
1127
86
CS444
NOMESCO Finland
Visual field testing with Octopus automated perimetry
49.4
323.0
433
103
S01EE03
ATC
bimatoprost; ophthalmic
196.1
323.0
845
61
CHD00
NOMESCO Finland
Laser trabeculoplasty
2272.1
323.0
530
*
S01EE04
ATC
travoprost; ophthalmic
106.9
323.0
704
87
S01EB01
ATC
pilocarpine; ophthalmic
174.5
323.0
379
25
CHD05
NOMESCO Finland
Selective lasertrabeculoplasty
9992.3
323.0
755
*
Z96.1
ICD-10 Finland
Presence of intraocular lens
7.8
323.0
1338
2904
S01EC03
ATC
dorzolamide; ophthalmic
259.9
323.0
805
43
S01ED01
ATC
timolol; ophthalmic
117.0
323.0
1337
213
H40.11
ICD-10 Finland
Low pressure glaucoma
482.5
323.0
380
9
CHD15
NOMESCO Finland
Trabeculectomy and iridectomy
3549.3
323.0
327
*
S01EA02
ATC
dipivefrine; ophthalmic
883.9
323.0
384
5
CHD65
NOMESCO Finland
Nonpenetrating glaucoma surgery
+∞
323.0
456
*
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
4.7
319.1
1983
9288
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
8.1
297.2
742
1179
Z01.0
ICD-10 Finland
Examination of eyes and vision
5.7
273.4
938
2263
CHC05
NOMESCO Finland
Iridotomy
94.0
267.4
295
35
XCH00
NOMESCO Finland
Eye pressure measurement
14.7
265.7
467
375
XCH05
NOMESCO Finland
Eye pressure longterm registration
544.7
255.0
250
5
CHD35
NOMESCO Finland
Laser goniopuncture
2505.5
252.7
241
*
CHD50
NOMESCO Finland
Shunt operation on anterior chamber
+∞
227.1
215
*
CHD99
NOMESCO Finland
Other filtering operation
+∞
220.7
209
*
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
12.8
214.0
399
358
H40
ICD-10 Finland
Glaucoma
76.1
209.8
238
34
CS1H4
NOMESCO Finland
Retinal nerve fibre layer imaging
161.7
200.5
210
14
3651A
ICD-9 Finland
Glaucoma, Open-angle glaucoma[GLAUCOMA SIMPLEX (AVOKULMA)]
+∞
196.1
186
*
H20.1
ICD-10 Finland
Chronic iridocyclitis
41.5
188.1
237
62
CS494
NOMESCO Finland
Other visual field testing
27.5
187.1
261
104
H25.1
ICD-10 Finland
Senile nuclear cataract
3.2
184.0
1542
7659
H40.22
ICD-10 Finland
Chronic glaucoma with closed ventricular angle
+∞
162.0
154
*
CS3P4
NOMESCO Finland
Optic nerve head stereophotography
149.5
160.2
169
12
ZXC20
NOMESCO Finland
Use of chemical agents
11.5
146.9
286
274
WX100
NOMESCO Finland
Conjunctival surface anesthesia
3.8
146.6
744
2431
CFW99
NOMESCO Finland
Other operation on conjunctiva
1501.3
146.1
141
*
CS5Z4
NOMESCO Finland
Specialised imaging for glaucoma
33.1
142.6
189
61
CJB10
NOMESCO Finland
Laser discission of secondary cataract
4.1
141.4
645
1912
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
5.7
127.4
395
775
H26.4
ICD-10 Finland
After-cataract
3.6
123.6
667
2251
CS434
NOMESCO Finland
Visual field testing with Humphrey automated perimetry
22.7
123.0
181
85
Z3229
NOMESCO Finland
Other healthcare associate professional
4.2
122.3
529
1475
S01BA07
ATC
fluorometholone; ophthalmic (corticosteroids, plain)
14.4
115.1
200
148
S01BC03
ATC
diclofenac; ophthalmic
9.0
112.0
248
298
H40.8
ICD-10 Finland
Other glaucoma
553.3
108.5
107
*
ZXA05
NOMESCO Finland
Left side
2.6
108.4
1096
5533
H34.8
ICD-10 Finland
Other retinal vascular occlusions
9.0
103.8
230
276
3651B
ICD-9 Finland
Glaucoma, Open-angle glaucoma[GLAUCOMA CAPSULARE (AVOKULMA)]
+∞
103.8
99
*
ZXA00
NOMESCO Finland
Right side
2.5
103.6
1125
5869
CKD65
NOMESCO Finland
Pars plana or pars plicata vitrectomy
8.9
102.6
228
275
H40.4
ICD-10 Finland
Glaucoma secondary to eye inflammation
991.5
98.7
96
*
37510
ICD-8 Finland
Glaucoma, Chronicum simplex
+∞
97.4
93
*
CKD05
NOMESCO Finland
Puncture of vitreous body with injection of medication
4.5
92.2
356
875
ZXA10
NOMESCO Finland
Bilateral
2.6
90.4
808
3721
H26.2
ICD-10 Finland
Complicated cataract
16.5
88.6
145
92
CKC12
NOMESCO Finland
Photocoagulation of retina
6.1
85.4
245
429
S01BA01
ATC
dexamethasone; ophthalmic (corticosteroids, plain)
6.0
82.7
241
430
H40.19
ICD-10 Finland
Other primary glaucoma with open ventricular angle
+∞
82.7
79
*
Z3231
NOMESCO Finland
Registered nurse
2.3
81.9
997
5356
H40.20
ICD-10 Finland
Acute glaucoma with closed ventricular angle
+∞
81.6
78
*
WX002
NOMESCO Finland
Sedation and analgesia
2.5
80.2
772
3666
H33.0
ICD-10 Finland
Retinal detachment with retinal break
7.1
79.2
204
308
H43.1
ICD-10 Finland
Vitreous haemorrhage
8.0
79.0
186
245
CKD40
NOMESCO Finland
Endophotocoagulation of retina
13.3
78.8
141
111
CS424
NOMESCO Finland
Visual field testing with Goldmann perimetry
25.0
78.2
111
46
H40.1
ICD-10 Finland
Primary open-angle glaucoma
166.6
77.5
81
5
S01BA04
ATC
prednisolone; ophthalmic (corticosteroids, plain)
6.8
76.3
201
313
H16.0
ICD-10 Finland
Corneal ulcer
5.7
71.0
217
409
F93
ICPC
Glaucoma
69.3
70.7
81
12
H40.3
ICD-10 Finland
Glaucoma secondary to eye trauma
+∞
70.1
67
*
S01BC05
ATC
ketorolac; ophthalmic
3.9
69.1
309
861
TCW99
NOMESCO Finland
Other minor procedure in eye surgery
9.7
68.6
144
156
3708
FHL
Trabeculectomy or equivalent
684.0
68.3
67
*
3650A
ICD-9 Finland
Glaucoma, Borderline glaucoma [glaucoma suspect][SUSPICIO GLAUCOMATIS (AVOKULMA)]
+∞
68.0
65
*
H3603, E103
ICD-10 Finland
NA
22.8
65.2
95
43
CS2P4
NOMESCO Finland
Optic nerve head imaging
104.0
65.1
71
7
CHD10
NOMESCO Finland
Trabeculectomy
+∞
64.8
62
*
H40.12
ICD-10 Finland
Pigmentary glaucoma
+∞
64.8
62
*
CKD20
NOMESCO Finland
Removal of vitreous body substitute
21.6
63.4
94
45
H21.0
ICD-10 Finland
Hyphaema
40.6
62.9
79
20
CHB10
NOMESCO Finland
Puncture of anterior chamber of eye with irrigation
22.1
61.2
90
42
WX142
NOMESCO Finland
Sub-tenon anesthesy
22.1
59.9
88
41
S01FA01
ATC
atropine; ophthalmic
24.4
58.2
83
35
H04.10
ICD-10 Finland
Dry eye syndrome
3.1
57.6
350
1231
CHC03
NOMESCO Finland
Laser iridoplasty
558.5
55.8
55
*
S01FA04
ATC
cyclopentolate; ophthalmic
11.2
55.4
107
99
37597
ICD-8 Finland
Glaucoma, Suspicio glaucomatis
+∞
54.3
52
*
TCG10
NOMESCO Finland
Removal of sutures from cornea
19.6
53.7
82
43
TCA20
NOMESCO Finland
Peribulbar therapeutic injection into orbit
56.6
51.7
61
11
H36.03
ICD-10 Finland
Proliferative diabetic retinopathy
17.2
51.3
82
49
CFB00
NOMESCO Finland
Suture of conjunctiva
112.1
50.9
55
5
ZXE00
NOMESCO Finland
One hour or less
1.9
49.8
1163
7725
H3603, E113
ICD-10 Finland
NA
11.5
49.6
94
84
H44.5
ICD-10 Finland
Degenerated conditions of globe
173.0
49.0
51
*
CKC15
NOMESCO Finland
Panretinal photocoagulation
11.0
49.0
95
89
CKD15
NOMESCO Finland
Injection of vitreous substitute
19.4
48.5
74
39
CKC20
NOMESCO Finland
Cryopexy of undetached retina
33.3
47.4
62
19
H21.1
ICD-10 Finland
Other vascular disorders of iris and ciliary body
62.2
47.4
55
9
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
7.8
47.0
111
147
SPAT1009
SPAT
Measurement of intraocular pressure
8.8
46.7
102
119
CKD92
NOMESCO Finland
Combined vitrectomy and retinal procedure
9.6
46.1
96
103
S01EX
ATC
Other antiglaucoma preparations
+∞
44.9
43
*
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
6.5
44.9
121
194
TCG20
NOMESCO Finland
Laser suture lysis in cornea or sclera
+∞
42.8
41
*
CHF15
NOMESCO Finland
Cryotherapy of ciliary body
+∞
42.8
41
*
ZXE10
NOMESCO Finland
More than one and less than three hours
1.8
42.1
1092
7390
CKD91
NOMESCO Finland
Extended vitrectomy through pars plana
6.9
41.3
106
159
H18.1
ICD-10 Finland
Bullous keratopathy
24.6
41.1
58
24
Z94.7
ICD-10 Finland
Corneal transplant status
19.2
40.6
62
33
CKD93
NOMESCO Finland
Extended combined procedure on vitreous body and retina
16.0
40.5
66
42
ZXD20
NOMESCO Finland
Day surgery
2.3
40.0
421
2009
H35.39
ICD-10 Finland
Degeneration of macula and posterior pole
3.8
39.9
177
485
S01GX01
ATC
cromoglicic acid; ophthalmic
2.1
39.0
477
2436
A10AB01
ATC
insulin (human); parenteral (insulins and analog. for injection, fast-acting)
4.1
38.9
158
401
S01CA02
ATC
prednisolone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
6.8
38.2
99
151
CJ2M4
NOMESCO Finland
Scans and measurement printouts for intraocular lens power calculation
7.6
37.1
89
121
A10AA01
ATC
NA
5.2
37.0
119
238
H25.0
ICD-10 Finland
Senile incipient cataract
2.7
36.8
272
1073
CHB99
NOMESCO Finland
Other operation on anterior chamber and anterior chamber angle
131.7
36.8
39
*
CKC10
NOMESCO Finland
Local photocoagulation of retina
4.7
36.3
128
283
CKD10
NOMESCO Finland
Insufflation of vitreous cavity
5.7
36.0
106
191
S01AX11
ATC
[U] ofloxacin; ophthalmic
3.2
34.2
194
644
H36.09*E10.3
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic retinopathy
16.5
34.2
55
34
H25.8
ICD-10 Finland
Other senile cataract
2.0
33.7
514
2858
A10AA02
ATC
NA
3.4
33.3
169
517
TCG00
NOMESCO Finland
Protection of cornea and sclera with soft lens
23.9
33.1
47
20
CFD10
NOMESCO Finland
Repair of conjunctiva
55.0
32.3
38
7
T85.2
ICD-10 Finland
Mechanical complication of intraocular lens
14.6
31.5
53
37
CKD70
NOMESCO Finland
Excision of preretinal or epiretinal membrane
5.2
31.2
99
195
TCF00
NOMESCO Finland
Subconjunctival therapeutic injection
42.7
30.9
38
9
H26.02
ICD-10 Finland
Presenil cataract
4.7
30.8
107
233
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
12.7
30.8
55
44
S01EX05
ATC
netarsudil; ophthalmic
+∞
30.3
29
*
E10.2
ICD-10 Finland
Type 1 diabetes mellitus, With renal complications
12.9
29.3
52
41
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
3.7
29.0
131
365
H54.2
ICD-10 Finland
Moderate visual impairment, binocular
6.6
28.5
74
114
T89
ICPC
Diabetes insulin dependent
4.0
28.1
117
304
H20.9
ICD-10 Finland
Iridocyclitis, unspecified
10.8
28.0
54
51
H16.9
ICD-10 Finland
Keratitis, unspecified
6.3
27.9
75
121
2500B
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE ,TYYPPI I]
5.8
27.6
80
142
XCD10
NOMESCO Finland
Electrophysiological examination of eye
3.8
27.4
121
331
Z2221
NOMESCO Finland
Medical doctor
1.7
26.9
763
5140
H27.0
ICD-10 Finland
Aphakia
13.7
26.8
46
34
CG2T4
NOMESCO Finland
Topography assessment of cornea
9.8
26.2
53
55
37520
ICD-8 Finland
Glaucoma, Secondary
+∞
26.1
25
*
H31.4
ICD-10 Finland
Choroidal detachment
94.3
25.7
28
*
S01AD03
ATC
aciclovir; ophthalmic
3.2
25.6
141
459
CGG45
NOMESCO Finland
Full thickness transplantation of cornea using homograft
22.0
25.6
37
17
CG2X4
NOMESCO Finland
Optical coherence tomography (OCT) of cornea
11.3
25.6
48
43
H27.1
ICD-10 Finland
Dislocation of lens
10.4
25.5
50
49
ZXD10
NOMESCO Finland
Scheduled procedure
1.5
25.3
1075
8005
A10AB04
ATC
insulin lispro; parenteral (insulins and analog. for injection, fast-acting)
4.0
24.9
103
267
CA1AE
NOMESCO Finland
Eye and orbita ultrasound examination
13.2
24.7
43
33
CWD00
NOMESCO Finland
Reoperation for superficial heamorrhage in eye and adjacent structures
131.1
24.6
26
*
A10AC01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate-acting)
2.1
24.4
292
1461
CKD94
NOMESCO Finland
Combined vitrectomy and procedure on lens through pars plana
5.0
24.4
80
165
R5210
NOMESCO Finland
Assessment of the improvements needed in the living environment
11.1
23.8
45
41
A10AE04
ATC
insulin glargine; parenteral
2.0
23.7
308
1593
H04AA01
ATC
glucagon; nasal, parenteral
5.7
23.7
69
124
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
2.2
23.2
250
1195
E10
ICD-10 Finland
Type 1 diabetes mellitus
6.4
22.8
60
95
XCD20
NOMESCO Finland
Photoangiography of eye
3.8
22.7
99
269
CHW99
NOMESCO Finland
Other operation on anterior chamber, anterior chamber angle, iris or ciliary body
121.0
22.6
24
*
H35.38
ICD-10 Finland
Preretinal fibrosis of the macula
3.0
22.5
131
444
CKD60
NOMESCO Finland
Anterior vitrectomy
5.5
21.7
65
121
H54.4
ICD-10 Finland
Blindness, monocular
18.5
21.7
33
18
H3601, E103
ICD-10 Finland
NA
8.6
21.3
46
54
H57.1
ICD-10 Finland
Ocular pain
3.8
20.6
89
241
E11.3
ICD-10 Finland
Type 2 diabetes mellitus, with ophthalmic complications
3.1
20.5
117
391
H40.6
ICD-10 Finland
Glaucoma secondary to drugs
+∞
19.8
19
*
H36.01
ICD-10 Finland
Diabetic maculopathy
5.0
19.8
64
131
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.9
19.6
331
1882
F43
ICPC
Eye, Other diagnostic procedure
4.6
19.6
68
150
H54.1
ICD-10 Finland
Severe visual impairment, binocular
17.8
19.5
30
17
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.6
19.4
659
4592
H01.0
ICD-10 Finland
Blepharitis
2.6
19.1
141
554
XCW10
NOMESCO Finland
Assessment of vision
10.1
18.8
37
37
37512
ICD-8 Finland
Glaucoma, Chronicum capsulare
+∞
18.8
18
*
3652B
ICD-9 Finland
Glaucoma, Primary angle-closure glaucoma[KROONINEN AHDASKULMAGLAUKOOMA]
+∞
18.8
18
*
S01EB02
ATC
carbachol; ophthalmic
+∞
18.8
18
*
H19.1*B00.5
ICD-10 Finland
Herpesviral keratoconjunctivitis
7.4
18.7
44
60
E10.1
ICD-10 Finland
Type 1 diabetes mellitus, With ketoacidosis
9.4
18.6
38
41
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
2.6
18.5
135
529
F99
ICPC
Eye/adnexa disease other
8.4
18.4
40
48
H33.4
ICD-10 Finland
Traction detachment of retina
13.6
18.2
31
23
H3600, E103
ICD-10 Finland
NA
7.5
17.6
41
55
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.4
17.6
1203
9661
3711
FHL
Cyclodiateria or cryocoagulation
181.0
17.5
18
*
R3120
NOMESCO Finland
Training in mobility skills
31.6
17.0
22
7
CJF30
NOMESCO Finland
Reduction of dislocation of artificial lens
10.8
16.9
32
30
H10.3
ICD-10 Finland
Acute conjunctivitis, unspecified
2.4
16.9
143
607
H52.1
ICD-10 Finland
Myopia
4.2
16.9
64
155
H40.29
ICD-10 Finland
Other [primary] glaucoma with closed ventricular angle
+∞
16.7
16
*
3656X
ICD-9 Finland
Glaucoma associated with other ocular disorders[GLAUCOMA SECUNDARIA ALIA SEU NUD]
+∞
16.7
16
*
3641A
ICD-9 Finland
Disorders of iris and ciliary body, Chronic iridocyclitis
35.2
16.7
21
6
CGG60
NOMESCO Finland
Reinforcement of sclera using graft
90.6
16.6
18
*
C08CA01
ATC
amlodipine; oral
1.4
16.1
1107
8856
J01DB01
ATC
cefalexin; oral
1.4
16.1
2028
18057
S01FA02
ATC
scopolamine; ophthalmic
5.5
16.0
47
87
H28.0*E10.3
ICD-10 Finland
Other specified diabetes mellitus - Diabetic cataract
21.1
16.0
23
11
WX110
NOMESCO Finland
Local anesthesy
1.4
16.0
1489
12564
103
Kela drug reimbursment
Diabetes, insulin-treated
1.5
15.9
808
6102
CWW99
NOMESCO Finland
Other reoperation on eye and adjacent structures
60.3
15.8
18
*
H20.8
ICD-10 Finland
Other iridocyclitis
15.7
15.7
25
16
H18.2
ICD-10 Finland
Other corneal oedema
15.7
15.7
25
16
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
7.0
15.6
38
55
H30.2
ICD-10 Finland
Posterior cyclitis
17.3
15.6
24
14
M08.3
ICD-10 Finland
Juvenile polyarthritis (seronegative)
22.2
15.5
22
10
S01BA09
ATC
clobetasone; ophthalmic
38.3
15.4
19
5
H02.4
ICD-10 Finland
Ptosis of eyelid
2.8
15.3
98
354
H35.36
ICD-10 Finland
Macular cyst
6.1
15.3
41
68
3626
FHL
Extracapsular cataract surgery and implantation of an artificial lens
2.9
15.2
94
334
25000
ICD-8 Finland
Diabetes mellitus, Sine complicatione
2.7
15.2
104
394
CKD50
NOMESCO Finland
Endodiathermy of retina
20.1
15.1
22
11
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.5
14.9
521
3623
M08.0
ICD-10 Finland
Juvenile rheumatoid arthritis
15.1
14.9
24
16
3663A
ICD-9 Finland
Cataract secondary to ocular disorders
12.5
14.8
26
21
E10.00
ICD-10 Finland
Insulin-dependent diabetes diabetic hypoglycemic coma
6.3
14.8
39
63
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
1.7
14.8
300
1804
TCA15
NOMESCO Finland
Retrobulbar therapeutic injection into orbit
57.0
14.8
17
*
H3603, E109
ICD-10 Finland
NA
57.0
14.8
17
*
A10AE05
ATC
insulin detemir; parenteral
2.1
14.8
161
774
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
1.9
14.7
223
1219
CA1CG
NOMESCO Finland
Eye and orbita extensive MRI examination with high intensity magnet
9.8
14.7
29
30
H26.3
ICD-10 Finland
Drug-induced cataract
7.5
14.7
34
46
3703
FHL
Laser operation on ventricular angle under general anesthesia
+∞
14.6
14
*
L04AB04
ATC
adalimumab; parenteral
4.9
14.5
47
98
3719
FHL
Other measure in this category
150.7
14.5
15
*
Q15.0
ICD-10 Finland
Congenital glaucoma
150.7
14.5
15
*
SPAT1262
SPAT
Handing over of treatment supplies
1.5
14.4
510
3557
I10
ICD-10 Finland
Essential (primary) hypertension
1.4
14.3
1778
15596
CG2S4
NOMESCO Finland
Photography of cornea
9.1
14.2
29
32
Z49.1
ICD-10 Finland
Extracorporeal dialysis
4.3
14.1
51
119
E10.8
ICD-10 Finland
Type 1 diabetes mellitus, With unspecified complications
5.3
14.0
42
80
F38
ICPC
Eye, Other laboratory test NEC
10.9
14.0
26
24
CJF15
NOMESCO Finland
Secondary implantation of skleral fixed artificial lens in posterior chamber
14.8
13.6
22
15
ZXD05
NOMESCO Finland
Urgent procedure
1.4
13.5
793
6118
CKC60
NOMESCO Finland
Local buckling of sclera using implant
6.8
13.4
33
49
CA1ME
NOMESCO Finland
Ultrasound oculometry
5.1
13.3
41
81
R1220
NOMESCO Finland
Psychological examination of need and possibilities to rehabilitation
8.1
13.3
29
36
G63.2*E10.4
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic polyneuropathy
13.8
13.2
22
16
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
3.6
13.2
59
167
H3603, E107
ICD-10 Finland
NA
40.2
13.1
16
*
J01CA04
ATC
amoxicillin; systemic
1.4
13.0
1908
17047
H54.0
ICD-10 Finland
Blindness, binocular
16.8
13.0
20
12
CDC00
NOMESCO Finland
Enucleation of eye
28.5
12.9
17
6
L04AD02
ATC
tacrolimus; systemic (calcineurin inhibitors)
8.1
12.8
28
35
CKC70
NOMESCO Finland
Circular buckling of sclera
8.5
12.7
27
32
J45.9
ICD-10 Finland
Asthma, unspecified
1.5
12.7
450
3135
H35.31
ICD-10 Finland
Senile macular degeneration (atrophic)(exudative)
1.9
12.6
179
956
N08.39
ICD-10 Finland
Glomerular disorders in diabetes mellitus microalbuminuria
5.9
12.5
34
58
A10AD01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate- or long-acting comb. with fast-acting)
2.6
12.5
90
352
H36.09*E11.3
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic retinopathy
4.9
12.5
40
83
CHC00
NOMESCO Finland
Iridotomy
130.5
12.4
13
*
A98
ICPC
Health maint/preventive medicine
1.4
12.4
2331
21600
H10.1
ICD-10 Finland
Acute atopic conjunctivitis
3.2
12.3
63
199
M08.4
ICD-10 Finland
Pauciarticular juvenile arthritis
14.4
12.3
20
14
E10.4
ICD-10 Finland
Type 1 diabetes mellitus, With neurological complications
7.0
12.1
29
42
H44.4
ICD-10 Finland
Hypotony of eye
46.8
11.9
14
*
CK2P4
NOMESCO Finland
Optic nerve head light layer imaging (OCT)
46.8
11.9
14
*
S01KA02
ATC
hypromellose; ophthalmic
2.9
11.8
70
244
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.4
11.8
535
3917
A11CC03
ATC
alfacalcidol; systemic
2.7
11.6
78
295
H18.5
ICD-10 Finland
Hereditary corneal dystrophies
5.0
11.5
36
73
H02AB06
ATC
prednisolone; systemic
1.3
11.5
1188
9986
CKD95
NOMESCO Finland
Extended combined vitectomy and lens procedure through pars plana
8.6
11.5
24
28
CJF45
NOMESCO Finland
Removal and implantation of artificial lens in anterior chamber with iridectomy or iridotomy
10.1
11.5
22
22
3656F
ICD-9 Finland
Glaucoma associated with other ocular disorders[GLAUCOMA POST UVEITIDEM]
+∞
11.5
11
*
3661A
ICD-9 Finland
Cataract, Senile cataract
2.7
11.5
76
284
JLE03
NOMESCO Finland
Allogenic total transplantation of pancreas with pancreaticoenterostomy
120.5
11.4
12
*
127
Kela drug reimbursment
Transplant complication
4.3
11.3
41
97
TK800
NOMESCO Finland
Hemodialysis
3.1
11.3
62
206
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
2.7
10.9
72
267
TCG40
NOMESCO Finland
Measurement of higher-grade errors of refraction
6.3
10.9
28
45
H54.5
ICD-10 Finland
Severe visual impairment, monocular
7.8
10.9
24
31
N02BE01
ATC
paracetamol; systemic, rectal
1.4
10.8
2258
20940
CHB15
NOMESCO Finland
Puncture of anterior chamber of eye with replacement of aqueous
21.5
10.7
15
7
H3601, E113
ICD-10 Finland
NA
2.9
10.6
64
227
A02BC02
ATC
pantoprazole; systemic
1.3
10.6
1652
14646
J01AA02
ATC
doxycycline; systemic
1.3
10.5
1951
17712
H10.9
ICD-10 Finland
Conjunctivitis, unspecified
2.2
10.5
106
495
H01.1
ICD-10 Finland
Noninfectious dermatoses of eyelid
7.3
10.4
24
33
E10.5
ICD-10 Finland
Type 1 diabetes mellitus, With peripheral circulatory complications
7.3
10.4
24
33
H53.4
ICD-10 Finland
Visual field defects
2.8
10.4
66
241
N0830, E102
ICD-10 Finland
NA
110.4
10.4
11
*
CHB30
NOMESCO Finland
Goniotomy
+∞
10.4
10
*
165
Kela drug reimbursment
Preservative-free combination of bimatoprost and timolol
+∞
10.4
10
*
CGG99
NOMESCO Finland
Other reconstructive operations on cornea and sclera
32.6
10.3
13
*
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.3
10.3
982
8121
H18.8
ICD-10 Finland
Other specified disorders of cornea
5.3
10.3
30
57
E10.6
ICD-10 Finland
Type 1 diabetes mellitus, With other specified complications
7.1
10.3
24
34
H10.5
ICD-10 Finland
Blepharoconjunctivitis
3.6
10.2
44
123
H35.30
ICD-10 Finland
Kuhnt-Junius degeneration
1.7
10.2
215
1310
L04AA17
ATC
[U] adalimumab; parenteral
14.6
10.0
16
11
CJF20
NOMESCO Finland
Removal of artificial lens
14.6
10.0
16
11
H35.29
ICD-10 Finland
Other proliferative retinopathy
40.2
10.0
12
*
L04AA06
ATC
mycophenolic acid; systemic
3.6
9.9
43
121
J01FF01
ATC
clindamycin; systemic
1.4
9.8
597
4596
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
5.2
9.8
29
56
H31.3
ICD-10 Finland
Choroidal haemorrhage and rupture
26.1
9.8
13
5
A10AE06
ATC
insulin degludec; parenteral
2.9
9.8
58
204
H35.0
ICD-10 Finland
Background retinopathy and retinal vascular changes
5.4
9.8
28
52
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
4.0
9.8
38
97
R2120
NOMESCO Finland
Counselling and guidance concerning rehabilitation services and social security
4.8
9.7
31
65
N08.39*E11.2
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic nephropathy
3.0
9.6
53
178
WX408
NOMESCO Finland
General anesthesy, balanced
1.4
9.6
603
4661
F29
ICPC
Eye symptom/complaint other
1.7
9.6
181
1067
Z94.0
ICD-10 Finland
Kidney transplant status
4.3
9.6
34
80
Z90.0
ICD-10 Finland
Acquired absence of part of head and neck
11.4
9.5
17
15
CJF10
NOMESCO Finland
Secondary implantation of artificial lens in posterior chamber
11.4
9.5
17
15
196
Kela drug reimbursment
Paricalcitol and cinacalcet
8.4
9.5
20
24
TPH04
NOMESCO Finland
Cathetrisation of vein
1.4
9.5
517
3901
CGG31
NOMESCO Finland
Posterior corneal lamellar transplantation
10.1
9.5
18
18
H221, M084
ICD-10 Finland
NA
+∞
9.4
9
*
CHC10
NOMESCO Finland
Peripheral iridectomy
+∞
9.4
9
*
CHB50
NOMESCO Finland
Trabeculotomy
+∞
9.4
9
*
3659X
ICD-9 Finland
Glaucoma, Unspecified glaucoma
+∞
9.4
9
*
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
3.2
9.3
48
154
V03AE02
ATC
sevelamer; oral
6.9
9.3
22
32
320
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
6.9
9.3
22
32
H36.00
ICD-10 Finland
Diabetic background retinopathy
3.2
9.2
47
150
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
1.7
9.2
179
1065
CKD99
NOMESCO Finland
Other intraoclular operations on vitreous body and retina
13.7
9.2
15
11
C10AA01
ATC
simvastatin; oral
1.3
9.1
1338
11668
H3600, E113
ICD-10 Finland
NA
2.9
9.1
53
185
H33.3
ICD-10 Finland
Retinal breaks without detachment
2.2
9.1
86
391
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
1.8
9.0
151
855
L04AA01
ATC
[U] ciclosporin; systemic
3.2
9.0
44
137
36402
ICD-8 Finland
Iritis, Iridocyclitis, uveitis chronica
18.6
8.9
13
7
H18.4
ICD-10 Finland
Corneal degeneration
7.5
8.9
20
27
E0000UV
ATC
NA
1.3
8.9
900
7471
H18.6
ICD-10 Finland
Keratoconus
6.8
8.8
21
31
CJE15
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in anterior chamber and iridectomy or iridotomy
3.1
8.8
46
150
CJF00
NOMESCO Finland
Secondary implantation of artificial lens in anterior chamber
10.7
8.8
16
15
R03AC02
ATC
salbutamol; inhalant
1.3
8.7
1159
9957
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
2.4
8.7
70
294
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.3
8.7
856
7071
S05.6
ICD-10 Finland
Penetrating wound of eyeball without foreign body
11.6
8.6
15
13
S01FA06
ATC
tropicamide; ophthalmic
11.6
8.6
15
13
CBJ40
NOMESCO Finland
Resection of levator muscle of eyelid
4.2
8.6
31
75
TCC40
NOMESCO Finland
Closure of lacrimal canaliculus with plug
9.0
8.5
17
19
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.3
8.5
681
5464
H34.1
ICD-10 Finland
Central retinal artery occlusion
4.1
8.4
31
76
H36.09
ICD-10 Finland
Diabetic retinopathy (E10-E14+ with common fourth character .3)
5.6
8.4
23
41
3651D
ICD-9 Finland
Glaucoma, Open-angle glaucoma[GLAUCOMA PIGMENTOSUM]
+∞
8.3
8
*
S01EXXX
ATC
NA
+∞
8.3
8
*
3650B
ICD-9 Finland
Glaucoma, Borderline glaucoma [glaucoma suspect][SUSPICIO GLAUCOMATIS (AHDASKULMA)]
+∞
8.3
8
*
3702
FHL
Trabeculotomy
+∞
8.3
8
*
37598
ICD-8 Finland
Glaucoma, Aliud definitum
+∞
8.3
8
*
3652A
ICD-9 Finland
Glaucoma, Primary angle-closure glaucoma[AKUUTTI AHDASKULMAGLAUKOOMA]
+∞
8.3
8
*
37511
ICD-8 Finland
Glaucoma, Chronicum irritativum sive congestivum
+∞
8.3
8
*
WX144
NOMESCO Finland
Subconjunctival anesthesy
2.8
8.3
50
180
M45
ICD-10 Finland
Ankylosing spondylitis
3.0
8.2
45
153
CK9F4
NOMESCO Finland
Fluorescein angiography (FAG) of choroid and retina
4.5
8.2
27
60
H43.8
ICD-10 Finland
Other disorders of vitreous body
1.6
8.0
186
1167
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.4
8.0
390
2880
Z5132
NOMESCO Finland
Nursing associate professional
4.7
7.9
25
53
PA6DE
NOMESCO Finland
Neck artery ultrasound examination with Doppler method
1.7
7.9
152
905
H04.5
ICD-10 Finland
Stenosis and insufficiency of lacrimal passages
2.6
7.9
56
222
A28
ICPC
Limited function/disability NOS
1.3
7.9
532
4153
H17.9
ICD-10 Finland
Corneal scar and opacity, unspecified
10.8
7.8
14
13
H22.0*B02.3
ICD-10 Finland
Zoster iridocyclitis
10.8
7.8
14
13
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
3.5
7.8
34
98
H04.3
ICD-10 Finland
Acute and unspecified inflammation of lacrimal passages
4.8
7.7
24
50
H02AB04
ATC
methylprednisolone; systemic
1.4
7.7
343
2490
CDC40
NOMESCO Finland
Evisceration of eye with insertion of prosthesis
45.1
7.7
9
*
CHD60
NOMESCO Finland
Deep sclerectomy without implant
45.1
7.7
9
*
3610A
ICD-9 Finland
Retinal detachments and defects, Retinal detachment with retinal defect
5.9
7.7
20
34
H46
ICD-10 Finland
Optic neuritis
7.4
7.7
17
23
4AA12
NOMESCO Finland
NA
18.4
7.6
11
6
2501B
ICD-9 Finland
Diabetes mellitus, Diabetes with ketoacidosis[DIABETES MELLITUS CUM KETOACIDOSI ,TYYPPI I]
11.9
7.6
13
11
CJG15
NOMESCO Finland
Extraction of dislocated lens with implantation of artificial lens in anterior chamber and iridectomy or iridotomy
25.1
7.6
10
*
AA1AD
NOMESCO Finland
CT of head and brain
1.3
7.5
665
5394
25002
ICD-8 Finland
Diabetes mellitus, Retinopathia diabetica
8.9
7.5
15
17
Z49.0
ICD-10 Finland
Preparatory care for dialysis
3.8
7.5
30
80
CD2S4
NOMESCO Finland
Photography of eye
5.7
7.5
20
35
CBG00
NOMESCO Finland
Epilation of cilia by electrolysis
5.7
7.5
20
35
A10AA03
ATC
NA
3.1
7.5
39
128
T90
ICPC
Diabetes non-insulin dependent
1.3
7.4
571
4540
CDC10
NOMESCO Finland
Enucleation of eye with insertion of prosthesis
80.3
7.4
8
*
BEF00
NOMESCO Finland
Continuous subcutaneous glucose monitoring
7.7
7.4
16
21
J05AB01
ATC
aciclovir; systemic
1.4
7.4
450
3455
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
1.6
7.3
179
1137
CHD20
NOMESCO Finland
Posterior sclerotomy
+∞
7.3
7
*
S01EB03
ATC
ecothiopate; ophthalmic
+∞
7.3
7
*
CHD30
NOMESCO Finland
Laser trabeculectomy
+∞
7.3
7
*
H221, M083
ICD-10 Finland
NA
+∞
7.3
7
*
H3603, H405
ICD-10 Finland
NA
+∞
7.3
7
*
R00.1
ICD-10 Finland
Bradycardia, unspecified
1.8
7.3
110
606
S01AA01
ATC
chloramphenicol; ophthalmic (antibiotics)
1.8
7.3
130
755
H15.1
ICD-10 Finland
Episcleritis
4.0
7.3
27
68
M14.6*E10.6
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic neuropathic
20.1
7.1
10
5
CA1CM
NOMESCO Finland
Eye and orbita extensive MRI examination with 3 Tesla magnet
7.9
7.1
15
19
R03AK06
ATC
salmeterol and fluticasone; inhalant
1.4
7.1
342
2519
S01BC01
ATC
indometacin; ophthalmic
12.0
7.1
12
10
F27
ICPC
Fear of eye disease
3.8
7.0
28
75
H33.5
ICD-10 Finland
Other retinal detachments
4.3
7.0
24
56
L04AD01
ATC
ciclosporin; systemic
3.1
7.0
35
113
S05.1
ICD-10 Finland
Contusion of eyeball and orbital tissues
3.2
6.9
34
108
H05BX01
ATC
cinacalcet; oral
4.6
6.9
22
48
R53
ICD-10 Finland
Malaise and fatigue
1.3
6.9
560
4487
Z94.8
ICD-10 Finland
Other transplanted organ and tissue status
6.7
6.8
16
24
S01XA18
ATC
ciclosporin; ophthalmic
5.0
6.8
20
40
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.3
6.8
532
4242
T86.8
ICD-10 Finland
Failure and rejection of other transplanted organs and tissues
40.1
6.8
8
*
3793C
ICD-9 Finland
Other disorders of eye, Aphakia and other disorders of lens[PSEUDOPHAKIA]
3.7
6.8
27
73
ZYC01
NOMESCO Finland
Remote contact by phone
1.9
6.7
86
448
0147
NOMESCO Finland
NA
16.7
6.7
10
6
WX720
NOMESCO Finland
Own respiration
2.0
6.7
79
398
B05DA
ATC
Isotonic solutions
4.7
6.7
21
45
C08CA13
ATC
lercanidipine; oral
1.4
6.7
370
2795
H10.4
ICD-10 Finland
Chronic conjunctivitis
3.9
6.7
25
64
H25.2
ICD-10 Finland
Senile cataract, morgagnian type
3.4
6.6
29
85
CKW99
NOMESCO Finland
Other operation on choroid, vitreous body and retina
3.4
6.6
29
85
H57.9
ICD-10 Finland
Disorder of eye and adnexa, unspecified
3.7
6.6
26
70
V03AE03
ATC
lanthanum carbonate; oral
6.8
6.5
15
22
S05.0
ICD-10 Finland
Injury of conjunctiva and corneal abrasion without mention of foreign body
2.8
6.5
38
135
H02AB07
ATC
prednisone; oral
1.4
6.5
354
2666
CBJ30
NOMESCO Finland
Plastic repair of levator aponeurosis of eyelid
4.5
6.5
21
47
R01AD08
ATC
fluticasone; nasal
1.3
6.4
518
4137
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.3
6.4
741
6204
Z2446
NOMESCO Finland
Social worker
1.6
6.4
146
913
CWF00
NOMESCO Finland
Reoperation for insufficiency of anastomosis or suture in eye and adjacent structures
70.0
6.4
7
*
S01XA02
ATC
retinol; ophthalmic
3.5
6.4
27
77
J01MA02
ATC
ciprofloxacin; systemic
1.2
6.4
987
8550
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
1.9
6.4
81
423
H33.2
ICD-10 Finland
Serous retinal detachment
6.5
6.3
15
23
A10AD04
ATC
insulin lispro; parenteral (insulins and analog. for injection, intermediate- or long-acting comb. with fast-acting)
5.2
6.3
18
35
S01AA12
ATC
tobramycin; ophthalmic
5.2
6.3
18
35
H53.1
ICD-10 Finland
Subjective visual disturbances
1.7
6.3
123
736
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.2
6.3
996
8641
71200
ICD-8 Finland
Rheumatoid arthritis and allied conditions, Juvenile rheumatoid arthritis
11.0
6.3
11
10
H30.9
ICD-10 Finland
Chorioretinal inflammation, unspecified
11.0
6.3
11
10
CK2L4
NOMESCO Finland
Wide-field/panoramic imaging of ocular fundus
4.0
6.3
23
58
C03CA01
ATC
furosemide; systemic
1.2
6.3
1048
9149
S01FB01
ATC
phenylephrine; ophthalmic (sympathomimetics excl. antiglaucoma prep.)
18.0
6.3
9
5
ZZL00
NOMESCO Finland
Free graft of amniotic membrane
18.0
6.3
9
5
3656C
ICD-9 Finland
Glaucoma associated with other ocular disorders[GLAUCOMA NEOVASCULARE]
+∞
6.2
6
*
H40.2
ICD-10 Finland
Primary angle-closure glaucoma
+∞
6.2
6
*
3651E
ICD-9 Finland
Glaucoma, Open-angle glaucoma[GLAUCOMA INFANTILE SEU JUVENILE]
+∞
6.2
6
*
S01EA01
ATC
epinephrine; ophthalmic
+∞
6.2
6
*
CGG20
NOMESCO Finland
Epikeratofakia or keratofakia
+∞
6.2
6
*
3651C
ICD-9 Finland
Glaucoma, Open-angle glaucoma[MATALAPAINEGLAUKOOMA]
+∞
6.2
6
*
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
1.8
6.2
107
618
H18.3
ICD-10 Finland
Changes in corneal membranes
26.7
6.2
8
*
H360, E113
ICD-10 Finland
NA
26.7
6.2
8
*
H3603, E117
ICD-10 Finland
NA
26.7
6.2
8
*
A02BC05
ATC
esomeprazole; systemic
1.2
6.2
917
7899
SPAT1325
SPAT
Vaccination
1.2
6.2
939
8109
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
1.7
6.2
120
719
I95.9
ICD-10 Finland
Hypotension, unspecified
2.5
6.1
45
184
S01GX08
ATC
ketotifen; ophthalmic
2.1
6.1
61
287
N18.0
ICD-10 Finland
End-stage renal disease
2.7
6.1
40
152
SPAT1014
SPAT
Treatment of eyes
2.2
6.1
58
266
CM2X4
NOMESCO Finland
Follow-up OCT of age-related macular degeneration lesions
3.2
6.1
29
91
H01.80
ICD-10 Finland
Prolonged inflammation in the edge of the eyelid
4.0
6.1
22
55
3620B
ICD-9 Finland
Other retinal disorders, Diabetic retinopathy[RETINOPATHIA DIABETICA PROLIFERATIVA]
12.5
6.1
10
8
H3602, E103
ICD-10 Finland
NA
12.5
6.1
10
8
3792A
ICD-9 Finland
Other disorders of eye, Disorders of vitreous body
12.5
6.1
10
8
XQ800
NOMESCO Finland
Prick test
1.8
6.1
105
607
CGF10
NOMESCO Finland
Suture of laceration of cornea
8.6
6.0
12
14
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.3
6.0
388
3000
CJD20
NOMESCO Finland
Extracapsular cataract extraction with implantation of artificial lens in posterior chamber
6.7
6.0
14
21
PBL09
NOMESCO Finland
Construction of arteriovenous fistula from brachial artery
6.7
6.0
14
21
N20.1
ICD-10 Finland
Calculus of ureter
1.9
6.0
82
437
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
1.4
6.0
266
1928

Mortality – FinRegistry

Association

Association between endpoint H7_GLAUCOMAMEDICATION and mortality.

Females

Parameter HR [95% CI] p-value
H7_GLAUCOMAMEDICATION 0.897 [0.84, 0.96] 0.002
Birth year 0.99 [0.98, 1.0] 0.019

During the follow-up period (1.1.1998 — 31.12.2019), 5847 out of 15112 females with H7_GLAUCOMAMEDICATION died.

Males

Parameter HR [95% CI] p-value
H7_GLAUCOMAMEDICATION 0.969 [0.89, 1.06] 0.483
Birth year 0.986 [0.98, 1.0] 0.004

During the follow-up period (1.1.1998 — 31.12.2019), 3519 out of 9395 males with H7_GLAUCOMAMEDICATION died.

Mortality risk

Mortality risk for people of age

years, who have H7_GLAUCOMAMEDICATION.

N-year risk Females Males
1 0.089% 0.153%
5 0.487% 1.08%
10 1.161% 2.555%
15 2.208% 5.031%
20 3.784% 8.639%

Relationships between endpoints

Index endpoint: H7_GLAUCOMAMEDICATION – Use of antiglaucoma preparations and miotics

GWS hits: 8

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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