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This is a non-core endpoint: only basic statistics are computed.

See these related core endpoints for full statistics:

Hypothyroidism and >3 levothyroxin purchases

HYPOTHY_PURCHASE

hypothyroidism: Abnormally low levels of thyroid hormone.

Endpoint definition

FinnGen phenotype data

414262 individuals

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Apply sex-specific rule None

414262

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Check conditions

HYPOTHYROIDISM

52227

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Check pre-conditions, main-only, mode, registry filters None

0 out of 7 registries used, show all original rules.

0

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Check minimum number of events None

0

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Include endpoints

51422

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Remove individuals based on genotype QC

46921

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HYPOTHY_PURCHASE

Extra metadata

First used in FinnGen datafreeze DF3

Similar endpoints

List of similar endpoints to Hypothyroidism and >3 levothyroxin purchases based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

Key figures

All Female Male
Number of individuals 46921 37498 9423
Unadjusted prevalence (%) 12.44 17.79 5.67
Mean age at first event (years) 51.79 50.13 58.39

Mortality

Not a core endpoint, no data to show.

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Not a core endpoint, no data to show.

Correlations

Index endpoint: HYPOTHY_PURCHASE – Hypothyroidism and >3 levothyroxin purchases
GWS hits:

Survival analyses between endpoints

Not a core endpoint, no data to show.

Drugs most likely to be purchased after Hypothyroidism and >3 levothyroxin purchases

Not a core endpoint, no data to show.