Intracerebral haemorrhage

I9_ICH

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 I61
  • Hospital discharge: ICD-9 431
  • Hospital discharge: ICD-8 431
  • Cause of death: ICD-10 I61
  • Cause of death: ICD-9 431
  • Cause of death: ICD-8 431

2 out of 7 registries used, show all original rules.

5286

4. Check minimum number of events

None

5286

5. Include endpoints

None

5286

6. Filter based on genotype QC (FinnGen only)

5286

Control definitions (FinnGen only)

Control exclude
I9_STR_EXH, I9_TIA

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
I60-I69
Name in latin
Haemorrhagia intracerebralis

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 79457 36219 41747
Only index persons 46894 21914 24980
Unadjusted period prevalence (%)
Whole population 1.11 1.04 1.17
Only index persons 0.88 0.81 0.95
Median age at first event (years)
Whole population 70.68 74.26 67.66
Only index persons 71.33 75.26 67.88

-FinnGen-

Key figures

All Female Male
Number of individuals 5286 2089 3197
Unadjusted period prevalence (%) 1.13 0.71 1.41
Median age at first event (years) 70.61 70.70 70.56

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
4719
Matched controls
47179
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
I61.1
ICD-10 Finland
Intracerebral haemorrhage in hemisphere, cortical
+∞
323.0
769
*
I69.1
ICD-10 Finland
Sequelae of intracerebral haemorrhage
324.1
323.0
1116
45
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
18.1
323.0
823
543
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
158.2
323.0
980
78
I61.9
ICD-10 Finland
Intracerebral haemorrhage, unspecified
6139.4
323.0
1945
5
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
46.5
323.0
519
125
K90
ICPC
Stroke/cerebrovascular accident
40.3
323.0
548
153
AA1AD
NOMESCO Finland
CT of head and brain
6.6
323.0
2325
6024
I61.0
ICD-10 Finland
Intracerebral haemorrhage in hemisphere, subcortical
16384.0
323.0
2026
*
I61.4
ICD-10 Finland
Intracerebral haemorrhage in cerebellum
+∞
313.0
297
*
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
9.1
299.5
672
844
I63.3
ICD-10 Finland
Cerebral infarction due to thrombosis of cerebral arteries
1542.6
296.7
286
*
PA2BD
NOMESCO Finland
Extensive CT angiography of brain
27.7
247.5
345
134
I61.8
ICD-10 Finland
Other intracerebral haemorrhage
2348.6
243.6
234
*
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
3.5
238.1
1393
5081
I63.4
ICD-10 Finland
Cerebral infarction due to embolism of cerebral arteries
803.5
235.5
230
*
N03AX14
ATC
levetiracetam; systemic
14.4
227.8
399
300
XA800
NOMESCO Finland
Neuropsychological investigation
11.6
208.1
404
379
N18
ICPC
Paralysis/weakness
18.6
199.3
315
181
AA5BD
NOMESCO Finland
CT of cerebral ischaemia
44.2
199.1
248
59
I61.5
ICD-10 Finland
Intracerebral haemorrhage, intraventricular
+∞
195.1
186
*
G45.1
ICD-10 Finland
Carotid artery syndrome (hemispheric)
331.7
191.8
193
6
I61.3
ICD-10 Finland
Intracerebral haemorrhage in brain stem
+∞
187.7
179
*
G40.9
ICD-10 Finland
Epilepsy, unspecified
9.2
184.2
404
474
I61.6
ICD-10 Finland
Intracerebral haemorrhage, multiple localized
1937.0
183.4
177
*
B01AC30
ATC
platelet aggregation inhibitors excl. heparin - combinations
8.0
182.8
440
601
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
16.2
181.2
301
197
I69.0
ICD-10 Finland
Sequelae of subarachnoid haemorrhage
25.1
177.0
253
106
K91
ICPC
Cerebrovascular disease
26.7
170.2
239
94
R4120
NOMESCO Finland
Occupational therapy
6.2
165.1
478
845
S06.3
ICD-10 Finland
Focal brain injury
15.5
163.8
277
189
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
13.7
159.5
284
219
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.9
157.3
1130
4562
I60.9
ICD-10 Finland
Subarachnoid haemorrhage, unspecified
14.6
155.9
270
195
S06.5
ICD-10 Finland
Traumatic subdural haemorrhage
5.9
155.6
465
854
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
12.5
153.2
285
242
AAB30
NOMESCO Finland
Evacuation of spontaneous intracranial haematoma
1522.8
149.7
145
*
AAF00
NOMESCO Finland
Ventriculostomy
32.0
142.9
191
62
N03AF02
ATC
oxcarbazepine; oral
8.1
136.2
321
420
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
4.8
135.5
494
1132
I60.1
ICD-10 Finland
Subarachnoid haemorrhage from middle cerebral artery
29.7
120.6
164
57
I61.2
ICD-10 Finland
Intracerebral haemorrhage in hemisphere, unspecified
+∞
117.1
112
*
I61
ICD-10 Finland
Intracerebral haemorrhage
175.7
114.9
120
7
R56.8
ICD-10 Finland
Other and unspecified convulsions
5.0
112.2
386
826
4310A
ICD-9 Finland
Intracerebral haemorrhage[HAEMORRHAGIA INTRACEREBRALIS CUM HYPERTONIA]
+∞
107.7
103
*
I63.0
ICD-10 Finland
Cerebral infarction due to thrombosis of precerebral arteries
1061.3
106.7
104
*
AAC00
NOMESCO Finland
Ligature of intracranial aneurysm
18.0
105.2
167
96
R47.0
ICD-10 Finland
Dysphasia and aphasia
32.5
97.9
130
41
I63.1
ICD-10 Finland
Cerebral infarction due to embolism of precerebral arteries
+∞
96.1
92
*
H53.4
ICD-10 Finland
Visual field defects
9.2
95.3
206
232
N03AG01
ATC
valproic acid; systemic, rectal
4.3
94.1
377
938
PA6BD
NOMESCO Finland
Extensive CT of neck arteries
6.6
91.2
245
386
R4150
NOMESCO Finland
Neuropsychological rehabilitation
45.8
90.9
112
25
R4130
NOMESCO Finland
Speech therapy
8.9
90.5
200
234
4311A
ICD-9 Finland
Intracerebral haemorrhage[HAEMORRHAGIA INTRACEREBRALIS HYPERTONIA NON INDICAT]
+∞
88.8
85
*
G45.0
ICD-10 Finland
Vertebro-basilar artery syndrome
231.7
88.7
91
*
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.9
87.4
1672
10378
WX892
NOMESCO Finland
Monitored bed care
3.2
86.9
501
1683
AAD15
NOMESCO Finland
Evacuation of traumatic intracerebral haematoma
117.2
85.2
92
8
PA7AD
NOMESCO Finland
CT angiography of head and neck vasculature
10.2
84.0
171
173
N19
ICPC
Speech disorder
15.6
82.5
138
91
4319X
ICD-9 Finland
Intracerebral haemorrhage[HAEMORRHAGIA INTRACEREBRALIS NUD]
+∞
82.5
79
*
N03AB02
ATC
phenytoin; systemic
9.3
80.2
172
191
I63.5
ICD-10 Finland
Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
770.3
77.5
76
*
I10
ICD-10 Finland
Essential (primary) hypertension
1.8
76.0
3009
23434
PA2BC
NOMESCO Finland
Cerebral extensive angiography with X-ray
16.4
74.7
122
76
N03AF01
ATC
carbamazepine; oral, rectal
3.5
73.5
368
1106
I64
ICD-10 Finland
Stroke, not specified as haemorrhage or infarction
83.5
73.2
82
10
PA2AD
NOMESCO Finland
CT angiography of brain
31.9
72.9
97
31
PA2CC
NOMESCO Finland
Cerebral very extensive angiography with X-ray
21.4
70.6
105
50
4340A
ICD-9 Finland
Occlusion of cerebral arteries, Cerebral thrombosis
+∞
69.9
67
*
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
3.2
67.6
379
1239
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
5.9
67.4
196
342
SPAT1226
SPAT
Implementation of occupational therapy rehabilitation plan
4.8
67.4
236
511
I67.1
ICD-10 Finland
Cerebral aneurysm, nonruptured
7.9
67.1
158
205
T90.5
ICD-10 Finland
Sequelae of intracranial injury
10.5
67.0
134
131
R1260
NOMESCO Finland
Evaluation of communicative skills
7.6
67.0
162
219
PA6DE
NOMESCO Finland
Neck artery ultrasound examination with Doppler method
4.6
65.7
240
543
R51.80
ICD-10 Finland
Headache
2.5
64.1
542
2297
XF400
NOMESCO Finland
ECG with 12 standard connections
2.0
63.1
934
5138
I63.8
ICD-10 Finland
Other cerebral infarction
100.0
63.0
69
7
D68.3
ICD-10 Finland
Haemorrhagic disorder due to circulating anticoagulants
18.6
62.4
97
53
S06.6
ICD-10 Finland
Traumatic subarachnoid haemorrhage
8.9
62.1
136
157
AAF05
NOMESCO Finland
Ventriculoperitoneal shunt
7.4
58.9
145
202
C08CA01
ATC
amlodipine; oral
1.7
57.7
1862
13193
I60.0
ICD-10 Finland
Subarachnoid haemorrhage from carotid siphon and bifurcation
22.8
57.1
83
37
PA7CD
NOMESCO Finland
CT angiography of neck and brain, extensive
17.6
56.8
90
52
G40.20
ICD-10 Finland
Complex partial seizures with only alteration of consciousness
10.8
56.6
111
105
I69.2
ICD-10 Finland
Sequelae of other nontraumatic intracranial haemorrhage
46.6
56.5
69
15
TKC20
NOMESCO Finland
Catheterisation of bladder
2.5
56.2
487
2082
A28
ICPC
Limited function/disability NOS
1.9
54.3
953
5553
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.0
54.1
834
4629
N03AX18
ATC
lacosamide; systemic
20.8
53.5
80
39
W19
ICD-10 Finland
Unspecified fall
2.3
52.8
524
2402
205
Kela drug reimbursment
Chronic hypertension
1.6
51.6
1698
11990
B01AA03
ATC
warfarin; systemic
1.7
50.4
1295
8508
4380A
ICD-9 Finland
Late effects of cerebrovascular disease[SEQUELAE MORBI CEREBROVASCULARIS]
18.0
49.7
78
44
I69.8
ICD-10 Finland
Sequelae of other and unspecified cerebrovascular diseases
27.5
49.5
68
25
AA5PD
NOMESCO Finland
CT examination of brain pefusion
37.5
49.4
63
17
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.7
48.9
1423
9675
B01AC07
ATC
dipyridamole; systemic
2.8
48.3
326
1203
WX730
NOMESCO Finland
Conventional respirator
5.1
48.1
156
311
G40.10
ICD-10 Finland
Simple partial seizures
13.3
48.0
85
65
G40.12
ICD-10 Finland
Simple partial seizures with secondary generalization
12.7
46.6
84
67
PA7BD
NOMESCO Finland
CT angiography of neck and brain
8.3
46.3
105
129
G41.9
ICD-10 Finland
Status epilepticus, unspecified
16.2
46.0
75
47
Q28.2
ICD-10 Finland
Arteriovenous malformation of cerebral vessels
24.4
45.8
65
27
G40.19
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
17.8
45.8
72
41
I63.2
ICD-10 Finland
Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
232.0
45.0
46
*
J69.0
ICD-10 Finland
Pneumonitis due to food and vomit
4.2
45.0
176
426
C09AA05
ATC
ramipril; oral
1.6
42.4
1309
8970
N28
ICPC
Limited function/disability (N)
5.7
41.8
124
223
R4110
NOMESCO Finland
Physiotherapy
1.7
41.8
1130
7464
L28
ICPC
Limited function/disability (L)
1.8
41.4
843
5105
Q28.3
ICD-10 Finland
Other malformations of cerebral vessels
23.9
41.4
59
25
SPAT1224
SPAT
Implementation of speech therapy rehabilitation plan
6.9
41.3
105
154
G40.2
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
9.5
41.2
86
92
FFM32
NOMESCO Finland
Occlusion or excision of atrial appendage transvenously with a closing device
58.0
39.3
46
8
G91.0
ICD-10 Finland
Communicating hydrocephalus
10.9
39.2
76
71
I60.8
ICD-10 Finland
Other subarachnoid haemorrhage
26.8
38.5
53
20
SPAT1216
SPAT
Assessment of functional ability
1.8
38.4
824
5065
PA3AC
NOMESCO Finland
Carotis angiography with X-ray
27.6
38.1
52
19
G81.9
ICD-10 Finland
Hemiplegia, unspecified
10.6
37.7
74
71
SPAT1229
SPAT
Assessment of need for aid
2.1
37.6
457
2279
FFW96
NOMESCO Finland
Other operation on atria
33.0
37.5
49
15
R1230
NOMESCO Finland
Neuropsychological evaluation of need and possibilities to rehabilitation
12.9
36.5
65
51
S06.0
ICD-10 Finland
Concussion
2.1
36.3
452
2279
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.4
36.1
337
1487
183
Kela drug reimbursment
Lamotrigin and topiramate
10.7
36.0
70
66
B01AC04
ATC
clopidogrel; oral
1.8
35.7
733
4432
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
2.3
35.5
342
1534
R47.1
ICD-10 Finland
Dysarthria and anarthria
9.3
35.1
74
81
GBB00
NOMESCO Finland
Tracheostomy
5.1
34.1
110
219
I60.2
ICD-10 Finland
Subarachnoid haemorrhage from anterior communicating artery
12.1
33.3
61
51
R42
ICD-10 Finland
Dizziness and giddiness
1.6
33.0
947
6298
R41.0
ICD-10 Finland
Disorientation, unspecified
2.8
32.4
216
789
43190
ICD-8 Finland
Cerebral haemorrhage, Intracerebralis, hypertonia non indicata
+∞
32.3
31
*
I48
ICD-10 Finland
Atrial fibrillation and flutter
1.5
31.7
1361
9962
AAD10
NOMESCO Finland
Evacuation of chronic subdural haematoma
4.2
31.5
124
303
S01.0
ICD-10 Finland
Open wound of scalp
2.1
31.5
394
1987
R53
ICD-10 Finland
Malaise and fatigue
1.6
31.0
912
6091
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
2.4
30.6
277
1203
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
2.4
30.6
282
1235
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.2
30.6
342
1643
SPAT1231
SPAT
Assessment of adjustments needed in living environment
3.4
30.4
154
467
N88
ICPC
Epilepsy
12.1
30.1
55
46
I62.9
ICD-10 Finland
Intracranial haemorrhage (nontraumatic), unspecified
17.8
29.6
46
26
PA2AC
NOMESCO Finland
Cerebral angiography with X-ray
21.7
29.5
43
20
R55
ICD-10 Finland
Syncope and collapse
1.8
29.3
550
3218
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
4.8
29.2
99
209
G40
ICD-10 Finland
Epilepsy
8.7
29.1
63
73
N05BA09
ATC
clobazam; oral
13.6
28.9
50
37
SPAT1137
SPAT
Taking care of patient’s/customer’s hygiene
2.0
28.9
379
1948
C07AB07
ATC
bisoprolol; oral
1.4
28.8
2304
18995
G45.3
ICD-10 Finland
Amaurosis fugax
22.9
28.7
41
18
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.6
28.3
800
5271
X59
ICD-10 Finland
Exposure to unspecified factor
1.7
28.2
711
4539
C02AC05
ATC
moxonidine; oral
2.4
28.1
246
1050
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.6
27.8
754
4912
AA1CD
NOMESCO Finland
Very extensive CT of head and brain
4.0
27.5
113
288
NA1AD
NOMESCO Finland
Cervical spine CT examination
2.7
27.5
196
748
A06AD11
ATC
lactulose; oral
1.6
27.3
833
5590
N05AH04
ATC
quetiapine; oral
1.7
27.3
565
3405
AA1BD
NOMESCO Finland
Extensive CT of head and brain
3.2
27.3
145
456
I69.4
ICD-10 Finland
Sequelae of stroke, not specified as haemorrhage or infarction
53.6
27.2
32
6
Z50.5
ICD-10 Finland
Speech therapy
6.1
27.1
75
125
43199
ICD-8 Finland
Cerebral haemorrhage, Without mention of hypertension
+∞
27.1
26
*
AAD05
NOMESCO Finland
Evacuation of acute subdural haematoma
7.6
26.7
63
84
PAF14
NOMESCO Finland
Thrombendarterectomy of internal carotid artery
9.3
26.4
55
60
M03BX01
ATC
baclofen; systemic
4.4
26.2
96
220
I62.0
ICD-10 Finland
Nontraumatic subdural haemorrhage
5.5
26.1
78
143
4318X
ICD-9 Finland
Intracerebral haemorrhage[HAEMORRHAGIA INTRACEREBRALIS ALIA DEFINITA]
+∞
26.1
25
*
AA1DM
NOMESCO Finland
Very extensive MRI examination of brain with 3 Tesla magnet
8.3
26.0
58
71
S06.2
ICD-10 Finland
Diffuse brain injury
5.1
25.8
83
166
M01AH05
ATC
etoricoxib; oral
0.7
25.4
1302
16571
I60.7
ICD-10 Finland
Subarachnoid haemorrhage from intracranial artery, unspecified
11.0
25.3
48
44
AAC40
NOMESCO Finland
Extirpation of intracranial arterio-venous malformation
70.2
24.8
28
*
I69
ICD-10 Finland
Sequelae of cerebrovascular disease
21.3
24.7
36
17
N06AB04
ATC
citalopram; systemic
1.6
24.3
817
5602
SPAT1215
SPAT
Assessment of need for medical rehabilitation
2.5
24.2
195
798
PA2LT
NOMESCO Finland
Endovascular closure of extensive brain aneurysm
15.7
24.1
39
25
D21
ICPC
Swallowing problem
4.3
24.0
91
216
AAL10
NOMESCO Finland
Intracranial endovascular thrombolysis
241.0
23.7
24
*
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
1.8
23.4
424
2447
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
1.8
23.2
441
2581
AA9CW
NOMESCO Finland
NA
20.1
23.0
34
17
C10AA01
ATC
simvastatin; oral
1.4
22.5
2105
17532
N05AX08
ATC
risperidone; systemic
1.8
22.3
395
2257
I60.6
ICD-10 Finland
Subarachnoid haemorrhage from other intracranial arteries
18.0
22.1
34
19
AAB10
NOMESCO Finland
Partial excision of intracranial lesion
5.8
21.8
62
108
N06AX11
ATC
mirtazapine; oral
1.4
21.7
1158
8733
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
2.2
21.6
224
1040
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
1.8
21.4
412
2420
SPAT1254
SPAT
Administration of medicine
1.6
21.4
666
4470
PA4AC
NOMESCO Finland
Vertebralis angiography with X-ray
23.2
21.2
30
13
AAB00
NOMESCO Finland
Extirpation of intracranial lesion
4.4
21.1
77
177
AAF20
NOMESCO Finland
Revision of shunt of ventricle of brain
8.2
21.1
47
58
XCK00
NOMESCO Finland
Perimetry
1.9
21.0
311
1671
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
1.9
20.9
306
1636
43100
ICD-8 Finland
Cerebral haemorrhage, Intracerebralis, cum hypertonia
+∞
20.8
20
*
4351A
ICD-9 Finland
Transient cerebral ischaemia, Vertebral artery syndrome
+∞
20.8
20
*
XX2BT
NOMESCO Finland
Other injection with X-ray guidance
19.5
20.8
31
16
XA400
NOMESCO Finland
EEG
8.1
20.6
46
57
Z02.4
ICD-10 Finland
Examination for driving licence
0.7
20.6
603
8537
PA2VT
NOMESCO Finland
Intravascular evacuation of brain artery embolus
210.7
20.6
21
*
AAA27
NOMESCO Finland
Insertion of intracerebral pressure monitoring device
30.1
20.5
27
9
SPAT1234
SPAT
Support of social functional capacity
2.0
20.5
277
1437
K89
ICPC
Transient cerebral ischaemia
10.1
20.3
40
40
N06AB10
ATC
escitalopram; oral
1.6
20.2
569
3723
I68.0
ICD-10 Finland
Cerebral amyloid angiopathy
48.2
20.1
24
5
A98
ICPC
Health maint/preventive medicine
0.7
19.9
3167
34676
N80
ICPC
Head injury other
3.6
19.9
91
257
S06.8
ICD-10 Finland
Other intracranial injuries
14.4
19.8
33
23
TPX22
NOMESCO Finland
Intravenous arterial thrombolysis
12.6
19.8
35
28
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.2
19.7
214
1015
I67.9
ICD-10 Finland
Cerebrovascular disease, unspecified
5.2
19.6
61
119
WX872
NOMESCO Finland
Intensive care
2.1
19.6
229
1122
SPAT1245
SPAT
Provision of support and information to patient’s family members
2.0
19.5
263
1361
I63
ICD-10 Finland
Cerebral infarction
13.8
19.5
33
24
N03AX09
ATC
lamotrigine; oral
2.8
19.1
123
444
I68.0*E85.9
ICD-10 Finland
Cerebral amyloid angiopathy
26.1
19.1
26
10
G91.1
ICD-10 Finland
Obstructive hydrocephalus
8.4
18.8
41
49
A49.9
ICD-10 Finland
Bacterial infection, unspecified
1.6
18.8
520
3384
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.5
18.8
631
4302
A12BA01
ATC
potassium chloride; oral
1.8
18.7
311
1740
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.5
18.4
603
4088
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
1.8
17.9
308
1746
4300A
ICD-9 Finland
Subarachnoid haemorrhage[HAEMORRHAGIA SUBARACHNOID. POST ANEURYSMA SACCULARE]
6.6
17.6
45
69
P20
ICPC
Memory disturbance
1.5
17.6
644
4477
TPH07
NOMESCO Finland
Cathetrisation of artery
1.6
17.5
442
2804
C09AA02
ATC
enalapril; systemic
1.4
17.5
1011
7691
G81.1
ICD-10 Finland
Spastic hemiplegia
31.5
17.0
22
7
PA6AD
NOMESCO Finland
CT of neck arteries
6.3
16.8
44
70
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
1.9
16.8
248
1333
S02.00
ICD-10 Finland
Fracture of the upper part of the head closed
7.2
16.7
40
56
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
1.6
16.4
434
2785
F80.1
ICD-10 Finland
Expressive language disorder
8.2
16.4
36
44
R11
ICD-10 Finland
Nausea and vomiting
1.8
16.4
306
1779
YKA02
NOMESCO Finland
Excision of kidneys from cadaver donor
40.2
16.3
20
5
AAK00
NOMESCO Finland
Cranioplasty
30.1
16.1
21
7
TPH04
NOMESCO Finland
Cathetrisation of vein
1.4
15.9
812
6025
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.7
15.8
316
1875
C03CA01
ATC
furosemide; systemic
1.3
15.7
1649
13736
F10.31
ICD-10 Finland
Withdrawal symptoms caused by alcohol with seizures
5.6
15.6
45
81
4359X
ICD-9 Finland
Transient cerebral ischaemia, Unspecified transient cerebral ischaemia
+∞
15.6
15
*
G40.89
ICD-10 Finland
Other epilepsy
9.2
15.6
32
35
G91.2
ICD-10 Finland
Normal-pressure hydrocephalus
3.0
15.6
89
296
G40.11
ICD-10 Finland
Simple partial epileptic seizure that develops into a complex partial seizure
17.2
15.6
24
14
2161
FHL
Neck ligation, big brain
6.3
15.6
41
66
RS221
NOMESCO Finland
NA
3.6
15.6
71
202
G93.90
ICD-10 Finland
Brain death
160.4
15.5
16
*
G91.9
ICD-10 Finland
Hydrocephalus, unspecified
6.5
15.3
39
60
SPAT1221
SPAT
Guidance concerning rehabilitation services and livelihood
3.3
15.3
78
242
XX3XW
NOMESCO Finland
NA
6.3
15.3
40
64
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.5
15.2
603
4253
E78.01
ICD-10 Finland
Pure hypercholesterolaemia
1.4
15.2
764
5645
F05.9
ICD-10 Finland
Delirium, unspecified
2.5
15.2
115
459
N30.0
ICD-10 Finland
Acute cystitis
1.5
15.1
503
3417
JDB10
NOMESCO Finland
Percutaneous gastrostomy
3.5
15.1
70
202
WX704
NOMESCO Finland
Intubation
1.8
15.0
249
1394
I65.2
ICD-10 Finland
Occlusion and stenosis of carotid artery
3.4
15.0
73
219
I67.6
ICD-10 Finland
Nonpyogenic thrombosis of intracranial venous system
13.9
15.0
25
18
SPAT1296
SPAT
Other function in accordance with occupational therapy nomenclature
3.6
15.0
66
183
AAG50
NOMESCO Finland
Stereotactic intracranial radiotherapy
6.8
14.9
37
55
PA2BG
NOMESCO Finland
MRI examination of vessels in the head with high intensity magnet
9.4
14.9
30
32
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
1.5
14.7
460
3080
L01AX03
ATC
temozolomide; systemic
5.7
14.6
41
72
4350A
ICD-9 Finland
Transient cerebral ischaemia, Basilar artery syndrome
+∞
14.6
14
*
C07AB02
ATC
metoprolol; systemic
1.3
14.5
1087
8593
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
1.9
14.5
215
1158
N05BA01
ATC
diazepam; systemic, rectal
1.5
14.3
518
3583
R47.8
ICD-10 Finland
Other and unspecified speech disturbances
5.7
14.3
40
70
P15
ICPC
Chronic alcohol abuse
2.8
14.3
89
317
PA2KT
NOMESCO Finland
Endovascular closure of brain aneurysm
17.0
14.3
22
13
C10AA05
ATC
atorvastatin; oral
1.3
14.2
1537
12809
315
Kela drug reimbursment
Clopidogrel
4.1
14.2
54
132
G40.09
ICD-10 Finland
Other or unspecified partial (focal) idiopathic epilepsy or epileptic syndrome with local onset
9.1
14.2
29
32
E78.5
ICD-10 Finland
Hyperlipidaemia, unspecified
1.6
14.1
385
2492
G41.2
ICD-10 Finland
Complex partial status epilepticus
14.4
14.0
23
16
G40.1
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
8.8
13.9
29
33
F10.24
ICD-10 Finland
Alcohol depence active use
3.9
13.9
57
149
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
2.1
13.8
153
736
F01.9
ICD-10 Finland
Vascular dementia, unspecified
2.7
13.8
96
366
4019X
ICD-9 Finland
Essential hypertension, Unspecified
2.0
13.8
186
968
WW806
NOMESCO Finland
Transfer from treating institution to lower-Level care, accompanied by doctor
53.4
13.8
16
*
AAK80
NOMESCO Finland
Partial excision of skull cap
53.4
13.8
16
*
S06.9
ICD-10 Finland
Intracranial injury, unspecified
5.2
13.7
42
82
C08CA02
ATC
felodipine; oral
1.5
13.6
470
3213
S02.11
ICD-10 Finland
Fracture of base of skull, open
6.4
13.6
35
55
H53.2
ICD-10 Finland
Diplopia
2.5
13.6
110
454
43198
ICD-8 Finland
Cerebral haemorrhage, Aliandefinita, hypertonia non indicata
+∞
13.5
13
*
RS313
NOMESCO Finland
NA
7.9
13.5
30
38
WX882
NOMESCO Finland
High dependency care
2.3
13.5
122
534
C79.30
ICD-10 Finland
Secondary malignant tumor of the cerebrum
3.8
13.5
56
148
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.3
13.5
1071
8530
C08CA05
ATC
nifedipine; systemic
1.6
13.5
325
2039
YJA10
NOMESCO Finland
Excision of liver from cadaver donor
140.3
13.4
14
*
SPAT1295
SPAT
Other function in accordance with physical therapy nomenclature
1.9
13.4
212
1166
PA2MT
NOMESCO Finland
Endovascular closure of very extensive brain aneurysm
18.2
13.3
20
11
GBB03
NOMESCO Finland
Percutaneous tracheostomy
21.2
13.3
19
9
G45.8
ICD-10 Finland
Other transient cerebral ischaemic attacks and related syndromes
21.2
13.3
19
9
XX3DW
NOMESCO Finland
Time consuming IT work
1.6
13.2
365
2368
C03AA03
ATC
hydrochlorothiazide; oral
1.5
13.1
461
3166
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.4
13.1
568
4076
F10.29
ICD-10 Finland
Addiction caused by alcohol UNS
2.7
13.1
90
341
G40.21
ICD-10 Finland
Partial epileptic seizure with cloudiness and automatism
7.4
12.9
30
41
SPAT1297
SPAT
Other function in accordance with speech therapy nomenclature
6.9
12.8
31
45
W10
ICD-10 Finland
Fall on and from stairs and steps
1.9
12.6
190
1027
A29
ICPC
General symptom/complaint other
1.5
12.5
437
2997
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
1.7
12.5
285
1759
A10AC01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate-acting)
1.6
12.5
331
2126
S42.2
ICD-10 Finland
Fracture of upper end of humerus
1.8
12.3
195
1074
127
Kela drug reimbursment
Transplant complication
3.6
12.3
55
156
SPAT1252
SPAT
Overall medication plan or its review
1.6
12.2
309
1960
N29
ICPC
Neurological sympt/complt other
2.7
12.1
82
309
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
2.1
12.0
139
682
I60.3
ICD-10 Finland
Subarachnoid haemorrhage from posterior communicating artery
11.0
12.0
22
20
T36
ICD-10 Finland
Poisoning by systemic antibiotics
2.2
12.0
117
534
L04AA06
ATC
mycophenolic acid; systemic
3.3
11.8
59
182
TAB00
NOMESCO Finland
Lumbar puncture
2.1
11.8
126
597
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.5
11.7
410
2811
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.3
11.7
1044
8427
APM
HP
Auricle closure
65.1
11.6
13
*
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
1.8
11.6
211
1219
S06.4
ICD-10 Finland
Epidural haemorrhage
8.6
11.5
24
28
TK800
NOMESCO Finland
Hemodialysis
2.4
11.5
92
382
D43.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Brain, supratentorial
5.1
11.5
35
69
F10.25
ICD-10 Finland
Alcohol dependence continuous use
3.0
11.5
66
224
G942, I615
ICD-10 Finland
NA
+∞
11.5
11
*
XXA00
NOMESCO Finland
Clinical examination requiring general anaesthesia
5.4
11.4
33
61
A04
ICPC
Weakness/tiredness general
1.4
11.4
480
3423
AA7AA
NOMESCO Finland
Liquor cerebri shunt X-ray examinatin without contrast
7.8
11.3
25
32
C09BA02
ATC
enalapril and diuretics; systemic
1.5
11.3
399
2740
WYA20
NOMESCO Finland
Home visit
2.4
11.3
90
373
AAF25
NOMESCO Finland
Removal of shunt of ventricle of brain
10.5
11.2
21
20
G41.0
ICD-10 Finland
Grand mal status epilepticus
9.6
11.2
22
23
AAL00
NOMESCO Finland
Endovascular occlusion of intracranial aneurysm
7.3
11.2
26
36
AA1AG
NOMESCO Finland
Short MRI examination of brain with median intensity magnet
3.8
11.0
45
119
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
1.7
10.9
248
1531
2BD01
NOMESCO Finland
NA
6.6
10.9
27
41
PA2HT
NOMESCO Finland
Extensive embolisation of arterio-venous malformation of the brain
43.4
10.9
13
*
R01AD58
ATC
fluticasone, combinations; inhalant, nasal
0.6
10.9
239
3610
SPAT1293
SPAT
Other function in accordance with rehabilitation guidance nomenclature
5.0
10.9
34
69
R40.2
ICD-10 Finland
Coma, unspecified
3.4
10.9
51
151
XX1XW
NOMESCO Finland
Extensive written report from radiologist
2.5
10.7
80
320
A10AE04
ATC
insulin glargine; parenteral
1.5
10.6
358
2435
F03
ICD-10 Finland
Unspecified dementia
1.6
10.6
270
1722
3454A
ICD-9 Finland
Epilepsy, Partial epilepsy, with impairment of consciousness[EPILEPSIA GENERALISATA SECUNDARIA]
10.0
10.5
20
20
K78
ICPC
Atrial fibrillation/flutter
1.5
10.5
369
2537
PA2YT
NOMESCO Finland
Cerebral artery PTA with stent
14.2
10.5
17
12
43399
ICD-8 Finland
Cerebral thrombosis, Without mention of hypertension
+∞
10.4
10
*
43300
ICD-8 Finland
Cerebral thrombosis, Wtih hypertension (benign)
+∞
10.4
10
*
4341A
ICD-9 Finland
Occlusion of cerebral arteries, Cerebral embolism
+∞
10.4
10
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.4
10.3
485
3532
B01AB05
ATC
enoxaparin; parenteral
1.3
10.3
1141
9462
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
1.6
10.2
237
1476
R50.9
ICD-10 Finland
Fever, unspecified
1.4
10.2
493
3610
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
2.2
10.0
101
469
I67.3
ICD-10 Finland
Progressive vascular leukoencephalopathy
2.6
10.0
69
265
G41.8
ICD-10 Finland
Other status epilepticus
20.0
9.8
14
7
EBA15
NOMESCO Finland
Extraction of large number of teeth
1.9
9.8
143
770
M01AE01
ATC
ibuprofen; systemic, rectal
0.8
9.7
2908
31253
R20.2
ICD-10 Finland
Paraesthesia of skin
1.8
9.6
159
894
OAB43
SPAT
NA
0.5
9.6
72
1429
I67.8
ICD-10 Finland
Other specified cerebrovascular diseases
6.8
9.6
23
34
Z94.0
ICD-10 Finland
Kidney transplant status
3.6
9.6
41
114
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
2.4
9.6
78
326
R33
ICD-10 Finland
Retention of urine
1.4
9.5
401
2858
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
5.0
9.5
29
58
7803A
ICD-9 Finland
General symptoms, Convulsions
3.8
9.5
38
100
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.2
9.4
1727
15123
PA2JT
NOMESCO Finland
Very extensive embolisation of arterio-venous malformation of the brain
100.2
9.4
10
*
E78.00
ICD-10 Finland
Familial hypercholesterolaemia
1.8
9.4
168
967
N03AX23
ATC
brivaracetam; systemic
30.0
9.4
12
*
43599
ICD-8 Finland
Transient cerebral ischaemia, Without mention of hypertension
+∞
9.4
9
*
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
4.3
9.4
33
77
Z50.1
ICD-10 Finland
Other physical therapy
1.7
9.4
199
1208
N74
ICPC
Malignant neoplasm nervous system
21.7
9.3
13
6
I60.4
ICD-10 Finland
Subarachnoid haemorrhage from basilar artery
9.5
9.2
18
19
U04
ICPC
Incontinence urine
1.7
9.2
189
1137
ZSA00
NOMESCO Finland
Procedure related to previous procedure classified in chapter A
5.7
9.2
25
44
X58
ICD-10 Finland
Exposure to other specified factors
1.4
9.1
395
2829
G30.8
ICD-10 Finland
Other Alzheimer disease
1.9
9.1
121
630
I95.1
ICD-10 Finland
Orthostatic hypotension
1.8
9.1
162
936
R13
ICD-10 Finland
Dysphagia
1.6
9.1
235
1504
W17
ICD-10 Finland
Other fall from one level to another
1.8
9.1
141
778
G40.00
ICD-10 Finland
Benign childhood epilepsy with centrotemporal EEG spikes
11.5
9.0
16
14
N03AX15
ATC
zonisamide; oral
11.5
9.0
16
14
AAF15
NOMESCO Finland
Ventriculoatrial shunt
5.9
9.0
24
41
Z43.0
ICD-10 Finland
Attention to tracheostomy
9.0
9.0
18
20
AA1BM
NOMESCO Finland
MRI examination of brain with 3 Tesla magnet
3.5
9.0
40
115
AA1AA
NOMESCO Finland
Head X-ray examination
3.2
8.9
44
137
R1250
NOMESCO Finland
Evaluation of functional capability
2.4
8.9
74
313
N02BE01
ATC
paracetamol; systemic, rectal
1.2
8.9
3454
32510
G46.3*I67.9
ICD-10 Finland
Brain stem stroke syndrome (I60-I67+)
7.4
8.9
20
27
F01.19
ICD-10 Finland
Multi-infarct dementia without information on additional symptoms
6.1
8.9
23
38
G40.6
ICD-10 Finland
Grand mal seizures, unspecified (with or without petit mal)
5.2
8.9
26
50
G45
ICD-10 Finland
Transient cerebral ischaemic attacks and related syndromes
5.7
8.9
24
42
8000/3-C34.9
ICD-O-3
Neoplasm, malignant of lung, NOS
0.2
8.9
9
438
A41.9
ICD-10 Finland
Sepsis, unspecified
1.7
8.7
162
944
RP120
NOMESCO Finland
NA
50.0
8.7
10
*
H3603, E103
ICD-10 Finland
NA
4.1
8.6
32
79
R90.8
ICD-10 Finland
Other abnormal findings on diagnostic imaging of central nervous system
4.1
8.6
32
79
F10.39
ICD-10 Finland
Withdrawal symptoms caused by alcohol UNS
3.2
8.6
43
136
G91.8
ICD-10 Finland
Other hydrocephalus
11.6
8.6
15
13
PA6AM
NOMESCO Finland
Simple MRI examination of neck vasculature with 3 Tesla magnet
16.3
8.5
13
8
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
0.8
8.5
915
10909
W06
ICD-10 Finland
Fall involving bed
3.0
8.5
47
159
G94.2
ICD-10 Finland
Hydrocephalus in other diseases classified elsewhere
27.5
8.5
11
*
YA1AD
NOMESCO Finland
CT examination of head and neck for dose design of radiotherapy
3.2
8.4
41
127
H49.2
ICD-10 Finland
Sixth [abducent] nerve palsy
3.3
8.4
39
117
RL130
NOMESCO Finland
NA
7.8
8.3
18
23
R01AD12
ATC
fluticasone furoate; nasal
0.7
8.3
430
5615
4331A
ICD-9 Finland
Occlusion and stenosis of precerebral arteries, Carotid artery[OCCL/STENOSIS ARTERIAE CAROTIS CUM INFARCTU CEREBRI]
+∞
8.3
8
*
4349A
ICD-9 Finland
Occlusion of cerebral arteries, Cerebral artery occlusion, unspecified[OCCL/STENOS ARTER.CEREBRALES NUD CUM INFARCTU CEREB]
+∞
8.3
8
*
PA2CD
NOMESCO Finland
Very extensive CT angiography of brain arteries
+∞
8.3
8
*
C08DB01
ATC
diltiazem; oral
1.5
8.3
298
2055
Z02.7
ICD-10 Finland
Issue of medical certificate
1.6
8.3
203
1281
T85.0
ICD-10 Finland
Mechanical complication of ventricular intracranial (communicating) shunt
8.5
8.3
17
20
4373A
ICD-9 Finland
Other and ill-defined cerebrovascular disease, Cerebral aneurysm, nonruptured
8.5
8.3
17
20
SPAT1251
SPAT
Organisation of medication
1.7
8.2
163
972
W00
ICD-10 Finland
Fall on same level involving ice and snow
1.4
8.2
337
2391
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
2.1
8.2
93
456
E87.6
ICD-10 Finland
Hypokalaemia
1.9
8.2
115
614
N03AE01
ATC
clonazepam; systemic
1.6
8.2
184
1138
RS222
NOMESCO Finland
NA
2.7
8.2
54
205
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
1.4
8.2
451
3378
C71.23
ICD-10 Finland
Malignant tumor of temporal lobe grade IV glioma
8.1
8.1
17
21
E16.2
ICD-10 Finland
Hypoglycaemia, unspecified
2.6
8.0
56
218
F10.40
ICD-10 Finland
Withdrawal symptoms and delirium caused by alcohol without seizures
3.0
8.0
43
143
WW805
NOMESCO Finland
Transfer from treating institution to lower-Level care, accompanied by paramedic/nurse
22.0
8.0
11
5
I60
ICD-10 Finland
Subarachnoid haemorrhage
22.0
8.0
11
5
C02CA01
ATC
prazosin; oral
2.0
8.0
96
486
3451A
ICD-9 Finland
Epilepsy, Generalised convulsive epilepsy
7.2
7.9
18
25
R4120
SPAT
NA
7.2
7.9
18
25
J01EA01
ATC
trimethoprim; systemic
1.3
7.9
934
7767
K99
ICPC
Cardiovascular disease other
1.9
7.9
116
629
N03AX16
ATC
pregabalin; oral
1.3
7.9
782
6365
XFP96
NOMESCO Finland
Other intraoperative electrophysiological investigation in arhythmia or disturbance of impulse propagation
2.0
7.9
99
507
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
2.8
7.9
48
174
S00.0
ICD-10 Finland
Superficial injury of scalp
2.1
7.8
85
409
N06AX16
ATC
venlafaxine; oral
1.4
7.8
309
2177
R74
ICPC
Upper respiratory infection acute
0.7
7.8
368
4872
G40.51
ICD-10 Finland
Epileptic seizures related to alcohol
10.8
7.8
14
13
S70.0
ICD-10 Finland
Contusion of hip
1.7
7.8
146
856
Z51.5
ICD-10 Finland
Palliative care
1.5
7.8
267
1829
PA2CG
NOMESCO Finland
Extensive MRI examination of vessels in the head with high intensity magnet
9.4
7.8
15
16
K59.09
ICD-10 Finland
Constipation, unspecified
1.5
7.7
225
1482
SPAT1240
SPAT
Therapeutic discussion
1.6
7.7
213
1388
F05.8
ICD-10 Finland
Other delirium
3.1
7.7
39
125
G81
ICD-10 Finland
Hemiplegia
45.0
7.7
9
*
43090
ICD-8 Finland
Subarachnoid haemorrhage, Postaneurysma sacculare, hypertonia non indicata
5.0
7.7
23
46
F10.20
ICD-10 Finland
Alcohol dependence currently independent
2.4
7.7
60
248
A12AA04
ATC
calcium carbonate; oral
2.3
7.7
66
287
RS230
NOMESCO Finland
NA
4.6
7.7
25
55
103
Kela drug reimbursment
Diabetes, insulin-treated
1.2
7.6
1125
9588
R51
ICD-10 Finland
Headache
1.8
7.6
119
661
H53.1
ICD-10 Finland
Subjective visual disturbances
1.7
7.6
158
956
XF600
NOMESCO Finland
Bloodpressure measurement
1.5
7.6
225
1494
2132
FHL
Ventricular operators sunt
11.8
7.6
13
11
TFC25
NOMESCO Finland
Transseptal catheterisation of left atrium or ventricle
2.9
7.6
44
154
N05CF01
ATC
zopiclone; oral
1.2
7.5
1335
11591
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
1.9
7.5
105
562
F10.01
ICD-10 Finland
Alcohol-related acute intoxication with permanent or other somatic damage
3.8
7.4
29
76
A11CC03
ATC
alfacalcidol; systemic
2.0
7.4
91
462
G44.2
ICD-10 Finland
Tension-type headache
1.4
7.4
324
2328
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
0.8
7.3
754
9049
C09CA06
ATC
candesartan; oral
1.3
7.3
697
5646
43191
ICD-8 Finland
Cerebral haemorrhage, Subduralis non traumatica, hypertonia non indicata
+∞
7.3
7
*
AAK85
NOMESCO Finland
Replantation of previously excised part of skull cap
+∞
7.3
7
*
ZX120
NOMESCO Finland
Intravenous
1.4
7.3
321
2312
Z49.1
ICD-10 Finland
Extracorporeal dialysis
2.4
7.3
55
226
A10AE05
ATC
insulin detemir; parenteral
1.6
7.3
186
1193
N05BA04
ATC
oxazepam; oral
1.2
7.2
869
7236
SPAT1276
SPAT
Outlining of treatment with patient or their family members
1.9
7.2
96
502
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
3.3
7.2
34
104
PAN14
NOMESCO Finland
Plastic repair of arteries internal carotid artery
6.2
7.2
18
29
M17.0
ICD-10 Finland
Primary gonarthrosis, bilateral
0.7
7.2
308
4134
G41.1
ICD-10 Finland
Petit mal status epilepticus
20.0
7.1
10
5
RS312
NOMESCO Finland
NA
20.0
7.1
10
5
N05AD01
ATC
haloperidol; systemic
1.7
7.1
142
853
25000
ICD-8 Finland
Diabetes mellitus, Sine complicatione
1.9
7.1
103
557
SPAT1139
SPAT
Nutrition survey
1.8
7.1
122
699
N30.9
ICD-10 Finland
Cystitis, unspecified
1.5
7.1
198
1296
S82
ICPC
Naevus/mole
0.7
7.1
187
2721
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
2.8
7.0
42
151
I48.9
ICD-10 Finland
Atrial fibrillation and atrial flutter, unspecified
1.5
7.0
224
1515
N01
ICPC
Headache
1.5
6.9
200
1322
V03AE02
ATC
sevelamer; oral
4.0
6.9
25
62
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
2.2
6.8
66
304
F21
ICPC
NA
2.5
6.8
49
196
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.3
6.8
700
5721
E10.8
ICD-10 Finland
Type 1 diabetes mellitus, With unspecified complications
3.1
6.8
35
115
C07AB03
ATC
atenolol; systemic
1.4
6.8
281
2001
AA9PW
NOMESCO Finland
NA
40.1
6.8
8
*
G93.6
ICD-10 Finland
Cerebral oedema
40.1
6.8
8
*
B01AB10
ATC
tinzaparin; parenteral
1.5
6.7
221
1499
G31.2
ICD-10 Finland
Degeneration of nervous system due to alcohol
3.1
6.7
34
110
G81.0
ICD-10 Finland
Flaccid hemiplegia
16.7
6.7
10
6
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
2.6
6.7
44
167
A86
ICD-10 Finland
Unspecified viral encephalitis
4.3
6.7
23
54
SPAT1042
SPAT
Guidance concerning balance maintenance
3.4
6.7
30
89
PH1AE
NOMESCO Finland
Ultrasound examination of upper extremity veins
2.4
6.6
51
212
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
3.1
6.6
33
106
D43.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Central nervous system, unspecified
5.1
6.6
19
37
L82
ICD-10 Finland
Seborrhoeic keratosis
0.7
6.6
316
4167
ZXF05
NOMESCO Finland
Interruption of procedure for other patient related reason
4.0
6.6
24
60
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.3
6.5
506
3988
XX9BW
NOMESCO Finland
Submitting image material and/or investigation material to authority or other institution
2.8
6.5
39
141
N99
ICPC
Neurological disease other
2.5
6.5
46
182
F10.09
ICD-10 Finland
Alcohol intoxication UNS
2.2
6.5
59
268
TAA40
NOMESCO Finland
Cathetrisation of cerebrospinal fluid through skin
6.2
6.4
16
26
L04AD02
ATC
tacrolimus; systemic (calcineurin inhibitors)
3.8
6.4
25
66
F01.30
ICD-10 Finland
Mixed cortical and subcortical vascular dementia without additional symptoms
4.5
6.4
21
47
2213
FHL
Hematoma removal, intracerebral or cerebral palsy reversion
69.9
6.4
7
*
D32.00
ICD-10 Finland
Benign tumor of the meninges on the outer surface of the cerebrum
2.5
6.4
47
192
N06AX21
ATC
duloxetine; oral
1.4
6.4
273
1957
ZXM00
NOMESCO Finland
Intraoperative use of ultrasonographic imaging
3.0
6.4
34
115
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
1.6
6.4
146
911
F10.21
ICD-10 Finland
Alcohol dependence currently abstinent, but staying in restrictive environment
3.2
6.4
30
93
A10BB01
ATC
glibenclamide; oral
1.4
6.3
249
1753
WX408
NOMESCO Finland
General anesthesy, balanced
1.2
6.3
886
7489
F07.9
ICD-10 Finland
Unspecified organic personality and behavioural disorder due to brain disease, damage and dysfunction
8.1
6.3
13
16
H36.01
ICD-10 Finland
Diabetic maculopathy
2.5
6.3
45
179
S00.9
ICD-10 Finland
Superficial injury of head, part unspecified
2.7
6.3
39
145
G40.4
ICD-10 Finland
Other generalized epilepsy and epileptic syndromes
11.0
6.3
11
10
F01.8
ICD-10 Finland
Other vascular dementia
11.0
6.3
11
10
N06DX01
ATC
memantine; oral
1.4
6.3
348
2609
N06DA04
ATC
galantamine; oral
1.8
6.3
104
592
JN5BD
NOMESCO Finland
Head and body CT examination for trauma
3.2
6.3
30
94
4301A
ICD-9 Finland
Subarachnoid haemorrhage[HAEMORRHAGIA SUBARACH.POST MALFORMAT.ARTERIOVENOSAM]
+∞
6.2
6
*
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
2.4
6.2
51
218
D68.8
ICD-10 Finland
Other specified coagulation defects
3.1
6.2
31
100
J69.1
ICD-10 Finland
Pneumonitis due to oils and essences
26.7
6.2
8
*
L57.0
ICD-10 Finland
Actinic keratosis
0.7
6.2
251
3398
ZXC95
NOMESCO Finland
Use of surgical navigator
2.7
6.2
38
140
A10AA01
ATC
NA
2.0
6.2
73
368
M05BB03
ATC
alendronic acid and colecalciferol; oral
1.8
6.2
101
572
Z08
ICPC
Social welfare problem
2.8
6.2
36
128
-2
ICPC
NA
2.8
6.1
37
135
A10AA02
ATC
NA
1.7
6.1
124
750
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
1.9
6.1
83
439
Z72.1
ICD-10 Finland
Alcohol use
2.6
6.1
41
159
E11.00
ICD-10 Finland
Non-insulin dependent diabetes diabetic hypoglycaemic coma
1.6
6.1
153
975
C08CA13
ATC
lercanidipine; oral
1.3
6.1
503
3997
3313A
ICD-9 Finland
Other cerebral degenerations, Communicating hydrocephalus
7.7
6.1
13
17
K92.0
ICD-10 Finland
Haematemesis
1.8
6.1
104
595
B18.2
ICD-10 Finland
Chronic viral hepatitis C
3.4
6.1
27
80
V03AA01
ATC
NA
2.2
6.1
54
243
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.3
6.1
541
4343
N03AX11
ATC
topiramate; oral
2.4
6.0
45
186
SPAT1100
SPAT
Long-term monitoring of blood pressure
1.4
6.0
294
2160
N02AA05
ATC
oxycodone; systemic
1.3
6.0
619
5056

Mortality – FinRegistry

Association

Association between endpoint I9_ICH and mortality.

Females

Parameter HR [95% CI] p-value
I9_ICH 2.719 [2.45, 3.02] < 0.001
Birth year 0.991 [0.98, 1.0] 0.029

During the follow-up period (1.1.1998 — 31.12.2019), 8418 out of 15911 females with I9_ICH died.

Males

Parameter HR [95% CI] p-value
I9_ICH 2.682 [2.41, 2.99] < 0.001
Birth year 0.984 [0.98, 0.99] < 0.001

During the follow-up period (1.1.1998 — 31.12.2019), 9468 out of 18816 males with I9_ICH died.

Mortality risk

Mortality risk for people of age

years, who have I9_ICH.

N-year risk Females Males
1 0.171% 0.377%
5 1.531% 2.647%
10 3.57% 6.822%
15 6.276% 12.305%
20 11.045% 20.278%

Relationships between endpoints

Index endpoint: I9_ICH – Intracerebral haemorrhage

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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