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Asthma (only as main-diagnosis)

J10_ASTHMA_MAIN

asthma: A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors resulting in recurring periods of wheezing (a whistling sound while breathing), chest tightness, shortness of breath, mucus production and coughing. The symptoms appear due to a variety of triggers such as allergens, irritants, respiratory infections, weather changes, exercise, stress, reflux disease, medications, foods and emotional anxiety.

Endpoint definition

FinnGen phenotype data

414262 individuals

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Apply sex-specific rule None

414262

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Check conditions None

414262

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Check pre-conditions, main-only, mode, registry filters

Check only main diagnosis Yes, side diagnoses are not checked
Hospital Discharge: ICD-10 J45, J46
Hospital discharge: ICD-9 493
Hospital discharge: ICD-8 493
Cause of death: ICD-10 J45, J46
Cause of death: ICD-9 493
Cause of death: ICD-8 493

2 out of 7 registries used, show all original rules.

37585

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Check minimum number of events None

37585

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Include endpoints None

37585

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Remove individuals based on genotype QC

34343

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J10_ASTHMA_MAIN

Control definitions

Control exclude J10_ASTHMA, ASTHMA_EXCL

Extra metadata

First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 34343 21278 13065
Unadjusted prevalence (%) 9.11 10.09 7.86
Mean age at first event (years) 42.54 41.30 44.55

Mortality

Not a core endpoint, no data to show.

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Not a core endpoint, no data to show.

Correlations

Index endpoint: J10_ASTHMA_MAIN – Asthma (only as main-diagnosis)
GWS hits:

Survival analyses between endpoints

Not a core endpoint, no data to show.

Drugs most likely to be purchased after Asthma (only as main-diagnosis)

Not a core endpoint, no data to show.