IBD patients in KELA-register

K11_KELAIBD

inflammatory bowel disease: A spectrum of small and large bowel inflammatory diseases of unknown etiology. It includes Crohn's disease, ulcerative colitis, and colitis of indeterminate type.

Endpoint definition

FinnGen phenotype data

414262 individuals

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Apply sex-specific rule None

414262

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Check conditions None

414262

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Check pre-conditions, main-only, mode, registry filters

KELA reimbursements: KELA codes 208|209

1 out of 7 registries used, show all original rules.

8162

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Check minimum number of events None

8162

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Include endpoints None

8162

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Remove individuals based on genotype QC

7625

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K11_KELAIBD

Control definitions

Control exclude K11_ENERCOLNONINF

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF3

Similar endpoints

List of similar endpoints to IBD patients in KELA-register based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

Key figures

All Female Male
Number of individuals 7625 3979 3646
Unadjusted prevalence (%) 2.02 1.89 2.19
Mean age at first event (years) 40.03 37.81 42.45

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.22 [0.87, 1.71] 2.4e-1 373
15 years 0.01 0.88 [0.66, 1.19] 4.1e-1 156
5 years 0.00 1.60 [1.18, 2.17] 2.4e-3 72
1 year 0.00 2.77 [1.75, 4.40] 1.5e-5 22

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: K11_KELAIBD – IBD patients in KELA-register
GWS hits: 52

Survival analyses between endpoints

Plot

before IBD patients in KELA-register
after IBD patients in KELA-register

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Drugs most likely to be purchased after IBD patients in KELA-register

Not a core endpoint, no data to show.