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Ulcerative colitis (strict definition, require KELA)

K11_UC_STRICT

ulcerative colitis: An inflammatory bowel disease involving the mucosal surface of the large intestine and rectum. It may present with an acute or slow onset and follows an intermittent or continuous course. Signs and symptoms include abdominal pain, diarrhea, fever, weight loss, and intestinal hemorrhage.

Endpoint definition

FinnGen phenotype data

414262 individuals

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Apply sex-specific rule None

414262

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Check conditions

K11_KELAUC

6138

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 K51
Hospital discharge: ICD-9 556
Hospital discharge: ICD-8 5631|569
Hospital discharge: excluded ICD-9 5564A
Cause of death: ICD-10 K51
Cause of death: ICD-9 556
Cause of death: ICD-8 5631|569
Cause of death: excluded ICD-9 5564A

2 out of 7 registries used, show all original rules.

5584

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Check minimum number of events None

5584

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Include endpoints None

5584

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Remove individuals based on genotype QC

5231

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K11_UC_STRICT

Control definitions

Control exclude K11_UC_STRICT_PSC
Control conditions not K11_KELAUC

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF3
Parent code in ICD-10 K50-K52
Name in latin Colitis ulcerosa

Similar endpoints

Summary Statistics

Key figures

All Female Male
Number of individuals 5231 2662 2569
Unadjusted prevalence (%) 1.39 1.26 1.55
Mean age at first event (years) 40.51 37.79 43.32

Mortality

Not a core endpoint, no data to show.

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Not a core endpoint, no data to show.

Correlations

Index endpoint: K11_UC_STRICT – Ulcerative colitis (strict definition, require KELA)
GWS hits:

Survival analyses between endpoints

Not a core endpoint, no data to show.

Drugs most likely to be purchased after Ulcerative colitis (strict definition, require KELA)

Not a core endpoint, no data to show.