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This is a non-core endpoint: only basic statistics are computed.

See its core counterpart C3_KAPOSI_SARCOMA_EXALLC for full statistics.

Kaposi sarcoma

C3_KAPOSI_SARCOMA

Kaposi's sarcoma: A malignant neoplasm characterized by a vascular proliferation which usually contains blunt endothelial cells. Erythrocyte extravasation and hemosiderin deposition are frequently present. The most frequent site of involvement is the skin; however it may also occur internally. It generally develops in people with compromised immune systems including those with acquired immune deficiency syndrome (AIDS).

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Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 C46
  • Cause of death: ICD-10 C46

2 out of 7 registries used, show all original rules.

61

4. Check minimum number of events

None

61

5. Include endpoints

None

61

6. Filter based on genotype QC (FinnGen only)

61

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
C45-C49
Name in latin
Sarcoma Kaposi

Similar endpoints

List of similar endpoints to Kaposi sarcoma based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Similar with more cases:

Venn diagram with a set fully inside an highlighted set Similar with less cases:

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 61 16 45
Unadjusted period prevalence (%) 0.02 0.01 0.02
Median age at first event (years) 72.97 66.89 75.13

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
52
Matched controls
520
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
C46.0
ICD-10 Finland
Kaposi sarcoma of skin
+∞
39.8
33
*
9140/3-C44.7
ICD-O-3
Kaposi sarcoma of skin of lower limb and hip
+∞
18.9
17
*
C46.9
ICD-10 Finland
Kaposi sarcoma, unspecified
+∞
11.9
11
*
C46.3
ICD-10 Finland
Kaposi sarcoma of lymph nodes
+∞
6.4
6
*
B23.1
ICD-10 Finland
HIV disease resulting in (persistent) generalized lymphadenopathy
+∞
6.4
6
*
C46.7
ICD-10 Finland
Kaposi sarcoma of other sites
+∞
6.4
6
*

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
18
40
5.97
8.29
1.7
1.4
—
—
—
0
0
16
42
4.81
5.99
2.1
1.2
—
—
—
0
0
16
48
4.16
5.02
1.8
1.6
—
—
—
0
0
12
32
4.42
4.33
4.6
1.5
—
—
—
0
0
14
44
3.83
4.07
2.4
1.3
—
—
—
0
0
10
25
4.59
3.87
4.7
1.4
—
—
—
0
0
29
149
2.80
3.75
3.9
2.1
—
—
—
0
0
7
11
7.02
3.28
1.6
1.4
—
—
—
0
0
5
5
10.72
3.03
1.4
1.0
—
—
—
0
0
8
19
4.68
2.78
1.6
1.1
—
—
—
0
0
12
44
3.15
2.73
2.4
1.5
—
—
—
0
0
23
122
2.42
2.63
5.1
2.6
—
—
—
0
0
24
130
2.40
2.62
11.0
5.1
—
—
—
0
0
29
177
2.22
2.35
14.4
5.8
58.0
59.3
%
0.23
29
164
34
230
2.08
2.04
12.4
6.5
9.9
11.9
umol/l
1.02
34
219
13
61
2.44
1.88
2.4
2.1
—
—
—
0
0
5
14
3.79
1.65
4.6
3.2
10.4
7.3
mmol/l
—
5
14
5
14
3.79
1.65
4.6
3.6
1.4
1.5
mmol/l
—
5
14
25
162
1.92
1.61
4.8
4.0
—
—
—
0
0
5
15
3.53
1.55
5.8
5.1
—
—
—
0
0
37
276
1.87
1.52
6.2
4.7
—
—
—
0
0
23
150
1.86
1.42
1.7
2.2
86.0
83.5
pmol/l
0.11
17
78
16
92
2.00
1.42
1.7
1.7
1.4
1.3
mmol/l
0.18
16
72
6
25
2.55
1.27
3.2
4.4
71.5
94.6
ng/l
—
6
19
18
112
1.86
1.27
4.4
3.5
361.3
4689.3
umol/l
0.50
18
95
16
96
1.90
1.26
15.7
6.9
—
—
—
0
0
10
50
2.20
1.24
1.1
1.3
—
—
—
0
0
7
31
2.42
1.14
1.4
1.4
—
—
—
0
0
7
32
2.34
1.12
5.6
4.3
0.1
0.1
e6/l
—
7
32
5
21
2.50
1.11
6.0
4.4
—
—
—
0
0
28
207
1.65
1.08
7.2
5.4
0.0
0.0
estimate
—
5
49
13
77
1.87
1.05
2.8
2.4
11.5
12.0
umol/l
0.06
13
67
7
36
2.06
1.00
1.6
4.0
60.6
65.0
g/l
—
7
31
25
183
1.62
0.98
35.8
12.1
1.8
1.3
inr
—
6
69
24
174
1.63
0.98
17.8
12.5
0.0
0.0
e9/l
0.05
19
147
28
211
1.60
0.98
5.2
4.3
0.0
0.0
estimate
—
6
47
12
72
1.83
0.93
2.8
2.5
2.3
2.3
g/l
0.01
12
64
27
206
1.56
0.87
5.1
4.2
0.0
0.0
estimate
—
6
50
6
32
1.97
0.84
5.3
4.1
—
7.4
—
0
5
5
23
2.27
0.78
4.6
2.7
27.5
25.1
mmol/l
—
5
23
5
25
2.09
0.74
4.6
2.8
131.6
127.0
g/l
—
5
25
17
122
1.55
0.70
2.3
3.0
—
—
—
0
0
18
132
1.52
0.67
8.4
5.1
—
—
—
0
0
5
30
1.72
0.63
2.2
2.2
—
—
—
0
0
6
34
1.85
0.60
4.3
2.8
4.9
4.0
kpa
—
6
34
0
23
0.00
0.59
0.0
1.7
—
—
—
0
0
6
36
1.74
0.58
1.0
3.4
—
—
—
0
0
6
38
1.64
0.56
7.8
4.9
—
—
—
0
0
6
39
1.60
0.55
1.5
1.2
—
—
—
0
0
6
39
1.60
0.55
12.3
4.9
0.0
0.6
%
—
6
13
46
420
1.39
0.44
34.4
21.2
83.3
87.6
umol/l
0.54
46
420
19
152
1.36
0.44
5.5
5.0
—
—
—
0
0
44
400
1.36
0.43
32.4
18.6
23.9
25.5
mg/l
0.16
38
330
16
125
1.38
0.42
6.1
3.7
—
—
—
0
0
11
82
1.42
0.37
15.0
6.3
—
—
—
0
0
6
43
1.44
0.36
4.3
3.4
—
—
—
0
0
6
44
1.40
0.35
4.3
3.3
2.9
2.3
mmol/l
—
6
38
6
45
1.37
0.35
4.3
3.3
6.3
5.9
kpa
—
6
45
15
120
1.33
0.34
3.7
3.4
198.8
586.2
mg/l
—
9
76
47
438
1.32
0.33
43.4
25.2
131.6
134.4
g/l
0.46
47
428
16
131
1.30
0.31
3.3
3.3
—
—
—
0
0
44
408
1.28
0.31
31.4
21.7
139.0
139.6
mmol/l
0.86
44
396
44
412
1.24
0.25
31.5
21.7
4.0
4.0
mmol/l
0.20
44
400
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
6
47
1.31
0.21
4.0
3.7
—
—
—
0
0
11
90
1.27
0.21
3.6
4.4
—
—
—
0
0
11
90
1.27
0.21
1.3
1.3
—
—
—
0
0
14
119
1.23
0.20
3.1
3.0
0.7
0.7
ug/l
—
9
74
46
438
1.20
0.18
43.9
25.0
30.7
30.3
pg
0.54
46
428
46
438
1.20
0.18
44.0
25.0
92.2
91.4
fl
0.57
46
428
15
132
1.18
0.15
4.3
4.5
0.0
0.0
estimate
—
5
44
15
134
1.16
0.12
1.9
2.6
52.1
55.1
u/l
0.09
15
128
28
262
1.13
0.12
4.1
3.6
15.7
15.0
pmol/l
0.60
23
225
40
384
1.12
0.10
13.6
5.2
6.1
6.1
mmol/l
0.00
35
344
35
339
1.08
0.05
27.5
17.7
38.3
40.2
%
0.31
22
222
30
290
1.07
0.04
4.8
4.5
—
—
—
0
0
40
408
0.94
0.02
27.7
17.1
—
—
—
0
0
14
137
1.03
0.00
4.6
3.4
—
—
—
0
0
15
145
1.05
0.00
2.3
2.1
150.5
288.5
u/l
0.53
15
137
0
8
0.00
0.00
0.0
2.0
—
208.6
—
0
8
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
2.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
2.8
—
68.3
—
0
5
0
5
0.00
0.00
0.0
2.6
—
5.3
—
0
5
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
6
60
1.00
0.00
1.8
7.8
4.8
4.9
kpa
—
6
55
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
2.7
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
239.0
—
0
5

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: C3_KAPOSI_SARCOMA – Kaposi sarcoma

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).