Small cell lung cancer, excluding all cancers (controls excluding all cancers)

C3_SCLC_EXALLC

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

  • HLP_C3_SCLC
942

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 C34
  • Hospital discharge: ICD-9 162
  • Hospital discharge: ICD-8 162
  • Cause of death: ICD-10 C34
  • Cause of death: ICD-9 162
  • Cause of death: ICD-8 162
  • Cancer registry: Topography ICD-O-3 C34
  • Cancer registry: Morphology ICD-O-3 8041
  • Cancer registry: Behaviour codes 3

3 out of 7 registries used, show all original rules.

942

4. Check minimum number of events

None

942

5. Include endpoints

942

6. Filter based on genotype QC (FinnGen only)

942

Control definitions (FinnGen only)

Control exclude
C3_CANCER, C3_CANCER_WIDE_EXALLC
Control conditions
not HLP_C3_SCLC

Extra metadata

First used in FinnGen datafreeze
DF12

Similar endpoints

List of similar endpoints to Small cell lung cancer, excluding all cancers (controls excluding all cancers) based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Similar with more cases:

Venn diagram with a set fully inside an highlighted set Similar with less cases:

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 942 210 732
Unadjusted period prevalence (%) 0.27 0.07 0.32
Median age at first event (years) 70.86 68.64 71.49

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
889
Matched controls
8889
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H02AB02
ATC
dexamethasone; systemic
191.5
323.0
343
29
8041/3-C34.9
ICD-O-3
Small cell carcinoma, NOS, of lung, NOS
+∞
323.0
577
*
130
Kela drug reimbursment
Malignant tumour
+∞
323.0
468
*
C34.16
ICD-10 Finland
Malignant tumor of the anterior, bronchial or pulmonary microcellular carcinoma
+∞
294.6
266
*
A03FA01
ATC
metoclopramide; systemic, rectal
20.1
267.4
444
420
L01CB01
ATC
etoposide; systemic
+∞
242.0
221
*
C34.1
ICD-10 Finland
Malignant neoplasm: Upper lobe, bronchus or lung
+∞
239.7
219
*
C34.86
ICD-10 Finland
Malignant overall tumor of bronchial and pulmonary microcellular carcinoma
+∞
201.9
186
*
UGC12
NOMESCO Finland
Flexible bronchoscopy
15.4
196.0
355
368
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
684.8
175.8
168
*
D38.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Trachea, bronchus and lung
54.2
175.8
209
50
C34.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of bronchus and lung
+∞
169.3
157
*
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
11.6
168.7
354
479
WF049
NOMESCO Finland
Radiotherapy of metastasis
+∞
165.9
154
*
C34.36
ICD-10 Finland
Malignant tumor of the lower lobe, bronchus or lung microcellular carcinoma
+∞
163.7
152
*
A04AA01
ATC
ondansetron; systemic, rectal
49.6
156.2
189
48
8041/3-C34.1
ICD-O-3
Small cell carcinoma, NOS, of upper lobe, lung
+∞
151.4
141
*
C34.3
ICD-10 Finland
Malignant neoplasm: Lower lobe, bronchus or lung
+∞
134.9
126
*
WF004
NOMESCO Finland
Palliative radiotherapy
1329.5
121.8
116
*
Z51.5
ICD-10 Finland
Palliative care
19.8
119.9
187
118
C34.9
ICD-10 Finland
Malignant neoplasm: Bronchus or lung, unspecified
+∞
114.0
107
*
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
623.3
113.6
110
*
C34.90
ICD-10 Finland
Malignant tumor in unspecified location in bronchus and lung without histology
+∞
111.8
105
*
A04AA02
ATC
granisetron; systemic, transdermal
1135.3
105.5
101
*
8041/3-C34.3
ICD-O-3
Small cell carcinoma, NOS, of lower lobe, lung
+∞
97.7
92
*
C34.96
ICD-10 Finland
Malignant tumor in unspecified localization in bronchial and pulmonary microcellular carcinoma
+∞
94.5
89
*
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
+∞
93.4
88
*
N02AA05
ATC
oxycodone; systemic
6.5
92.8
277
576
C34.06
ICD-10 Finland
Malignant tumor of the main bronchial microcellular carcinoma
+∞
88.0
83
*
WF002
NOMESCO Finland
Radical radiotherapy
453.4
84.5
83
*
C79.30
ICD-10 Finland
Secondary malignant tumor of the cerebrum
+∞
79.3
75
*
C34.99
ICD-10 Finland
Malignant tumor in unspecified localization in bronchial and pulmonary other or unspecified histology
+∞
79.3
75
*
YG1BD
NOMESCO Finland
Extensive CT examination of thorax for dose design of radiotherapy
+∞
77.2
73
*
C34.10
ICD-10 Finland
Malignant tumor of the upper lobe, bronchus or lung without histology
+∞
75.1
71
*
C34.0
ICD-10 Finland
Malignant neoplasm: Main bronchus
+∞
69.7
66
*
WD115
NOMESCO Finland
Multiple cystostatic therapy of methastized malignancy
721.1
69.0
67
*
GD5BD
NOMESCO Finland
Thorax and upper abdomen combined extensive CT examination of
22.5
64.7
95
47
L03AA13
ATC
pegfilgrastim; parenteral
+∞
63.3
60
*
JN4BD
NOMESCO Finland
Extensive body CT
8.8
61.9
140
184
XX3DW
NOMESCO Finland
Time consuming IT work
10.3
61.3
126
140
C34.80
ICD-10 Finland
Malignant overall tumor of bronchus and lung without histology
+∞
56.9
54
*
C34.19
ICD-10 Finland
Malignant tumor of the upper lobe, bronchus or lung other or unspecified histology
+∞
55.8
53
*
C78.7
ICD-10 Finland
Secondary malignant neoplasm of liver and intrahepatic bile duct
+∞
55.8
53
*
ZX090
NOMESCO Finland
Other technic of radiotherapy
+∞
53.7
51
*
8041/3-C34.0
ICD-O-3
Small cell carcinoma, NOS, of main bronchus
+∞
48.4
46
*
C34.00
ICD-10 Finland
Malignant tumor of the main bronchus without histology
+∞
46.2
44
*
ZX070
NOMESCO Finland
Intensity modified radiotherapy
459.3
44.6
44
*
8140/3-C61.9
ICD-O-3
Adenocarcinoma, NOS, of prostate gland
+∞
44.1
42
*
JN4AD
NOMESCO Finland
Body CT examination
10.0
43.7
90
99
D70.82
ICD-10 Finland
Drug-induced neutropenia
96.9
42.2
46
5
A04AA55
ATC
palonosetron, combinations; systemic
+∞
42.0
40
*
C34.30
ICD-10 Finland
Malignant tumor of the lower lobe, bronchus or lung without histology
+∞
42.0
40
*
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
150.3
41.1
43
*
YA1BD
NOMESCO Finland
Extensive CT examination of head and neck for dose design of radiotherapy
415.2
40.4
40
*
YG1CD
NOMESCO Finland
Very extensive CT examination of thorax for dose design of radiotherapy
+∞
39.9
38
*
A98
ICPC
Health maint/preventive medicine
0.4
39.5
337
5427
WB113
NOMESCO Finland
Multiple adjuvant cytostatic therapy
404.2
39.4
39
*
YX9AD
NOMESCO Finland
Other CT eamination for dose design of radiotherapy
+∞
38.8
37
*
XGX32
NOMESCO Finland
Bronchoscopic ultrasonography
75.0
38.3
43
6
C34.26
ICD-10 Finland
Malignant tumor of the middle lobe, bronchus or lung microcellular carcinoma
+∞
37.8
36
*
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
7.7
37.4
90
128
TGD00
NOMESCO Finland
Needle biopsy of lung
85.9
37.1
41
5
L03AA02
ATC
filgrastim; parenteral
104.5
37.0
40
*
R84
ICPC
Malignant neoplasm bronchus/lung
192.6
36.0
37
*
L03AA14
ATC
lipegfilgrastim; parenteral
+∞
35.6
34
*
ZX080
NOMESCO Finland
Image guided radiotherapy
+∞
35.6
34
*
YG1AD
NOMESCO Finland
CT examination of thorax for dose design of radiotherapy
+∞
34.6
33
*
1623B
ICD-9 Finland
Malignant neoplasm of trachea, bronchus and lung, Upper lobe, bronchus or lung[NEOPL MAL LOB SUPER PULMONIS,CA MICROCELLURE]
+∞
33.5
32
*
C34.2
ICD-10 Finland
Malignant neoplasm: Middle lobe, bronchus or lung
+∞
33.5
32
*
AA1BD
NOMESCO Finland
Extensive CT of head and brain
10.7
32.6
64
64
C61
ICD-10 Finland
Malignant neoplasm of prostate
56.5
32.5
38
7
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
6.1
31.5
89
158
AA1CD
NOMESCO Finland
Very extensive CT of head and brain
20.1
30.7
46
24
8041/3-C34.2
ICD-O-3
Small cell carcinoma, NOS, of middle lobe, lung
+∞
30.4
29
*
Z51.1
ICD-10 Finland
Chemotherapy session for neoplasm
+∞
30.4
29
*
UGC18
NOMESCO Finland
Flexible bronchoscopy with biopsy of lung
85.6
29.9
33
*
L01XX17
ATC
[U] topotecan; systemic
+∞
29.3
28
*
C34.39
ICD-10 Finland
Malignant tumor of the lower lobe, bronchus or lung other or unspecified histology
+∞
29.3
28
*
A04AD12
ATC
aprepitant; systemic
+∞
29.3
28
*
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
2.8
28.9
217
915
C34.12
ICD-10 Finland
Malignant tumor of the anterior, bronchial or pulmonary adenocarcinoma
+∞
26.2
25
*
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
2.5
26.0
245
1169
GD1CT
NOMESCO Finland
Biopsy of the lung with CT guidance
41.4
26.0
32
8
C34.89
ICD-10 Finland
Malignant overall tumor of the bronchus and lung other or unspecified histology
+∞
24.1
23
*
WW500
NOMESCO Finland
Blood transfusion
9.7
24.0
49
53
GD1AD
NOMESCO Finland
Thorax CT examination
6.3
23.9
65
110
1625B
ICD-9 Finland
Malignant neoplasm of trachea, bronchus and lung, Lower lobe, bronchus or lung[NEOPL MAL LOBI INFERIORIS PULMONIS,CA MICROCELLURE]
+∞
23.0
22
*
ZX095
NOMESCO Finland
Combined chemoradiotherapy
+∞
23.0
22
*
GD5AD
NOMESCO Finland
Thorax and upper abdomen combined CT examination of
23.6
22.7
32
14
A06AH03
ATC
naloxegol; oral
46.3
22.5
27
6
C79.5
ICD-10 Finland
Secondary malignant neoplasm of bone and bone marrow
+∞
22.0
21
*
116
Kela drug reimbursment
Prostate cancer
+∞
22.0
21
*
N06DX01
ATC
memantine; oral
0.0
21.8
*
623
Z51.0
ICD-10 Finland
Radiotherapy session
+∞
20.9
20
*
D38.6
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Respiratory organ, unspecified
+∞
19.9
19
*
N40
ICD-10 Finland
Hyperplasia of prostate
0.4
18.8
104
2159
WB121
NOMESCO Finland
Demanding neoadjuvant cytostatic therapy
+∞
18.8
18
*
WF003
NOMESCO Finland
Adjuvant radiotherapy
193.7
18.6
19
*
C34.11
ICD-10 Finland
Malignant tumor of the anterior, bronchial or pulmonary epidermoid carcinoma
+∞
17.8
17
*
R03AK03
ATC
[D] fenoterol & other drugs for obstructive airway dis; inhalant
2.5
16.9
141
617
I10
ICD-10 Finland
Essential (primary) hypertension
0.5
16.8
300
4316
GD1AT
NOMESCO Finland
Biopsy of the lung with ultrasound guidance
64.6
16.8
19
*
YX9BD
NOMESCO Finland
Other extensive CT eamination for dose design of radiotherapy
+∞
16.7
16
*
YA1AD
NOMESCO Finland
CT examination of head and neck for dose design of radiotherapy
+∞
16.7
16
*
C34.09
ICD-10 Finland
Malignant tumor of the main bronchus other or unspecified histology
+∞
16.7
16
*
N02AA01
ATC
morphine; systemic, rectal
9.3
16.5
34
38
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
11.0
16.0
30
28
C34.20
ICD-10 Finland
Malignant tumor of the middle lobe, bronchus or lung without histology
+∞
15.7
15
*
GD5CD
NOMESCO Finland
Thorax and upper abdomen combined very extensive CT examination of
26.8
15.6
21
8
PJ2AT
NOMESCO Finland
Biopsy of lymphnode with ultrasound guidance
86.6
15.6
17
*
WZC30
NOMESCO Finland
Teaching
3.3
15.6
82
268
TGE00
NOMESCO Finland
Needle biopsy of mediastinum
29.2
15.2
20
7
GAA10
NOMESCO Finland
Intercostal insertion of pleural drainage tube
8.1
14.9
33
42
H02AB06
ATC
prednisolone; systemic
1.8
14.9
405
2842
JN4CD
NOMESCO Finland
Very extensive body CT
8.3
14.6
32
40
C79.31
ICD-10 Finland
Secondary malignant tumor of the cerebellum
+∞
14.6
14
*
N07BA03
ATC
varenicline; oral
5.8
14.5
41
74
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.8
14.4
334
2221
P20
ICPC
Memory disturbance
0.3
14.1
27
902
G04CA02
ATC
tamsulosin; oral
0.5
13.6
139
2392
N06DA02
ATC
donepezil; oral
0.1
13.6
6
494
C78.0
ICD-10 Finland
Secondary malignant neoplasm of lung
+∞
13.6
13
*
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
+∞
13.6
13
*
G30.1
ICD-10 Finland
Alzheimer disease with late onset
0.2
13.3
11
596
J90
ICD-10 Finland
Pleural effusion, not elsewhere classified
3.5
13.1
63
192
R03BB04
ATC
tiotropium bromide; inhalant
2.1
12.6
160
849
WF090
NOMESCO Finland
Profylactic radiotherapy
+∞
12.5
12
*
8090/3-C44.3
ICD-O-3
Basal cell carcinoma, NOS, of skin of other and unspecified parts of face
+∞
12.5
12
*
C67.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of bladder
+∞
12.5
12
*
1628B
ICD-9 Finland
Malignant neoplasm of trachea, bronchus and lung, Other parts of bronchus or lung[NEOPL MAL PULMONIS LOCO MULTIPLICI,CA MICROCELLURE]
+∞
12.5
12
*
C34.15
ICD-10 Finland
Malignant tumor of the anterior, bronchial or lung other non-microcellular carcinoma
+∞
12.5
12
*
L02AE02
ATC
leuprorelin; implant, parenteral
131.7
12.5
13
*
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
0.5
12.1
110
1971
307
Kela drug reimbursment
Tacrine, donepezil, rivastigmine, galantamine and other major and expensive drugs used to treat Alzheimer's disease
0.2
12.0
13
595
SAA02
NOMESCO Finland
Basic examination of mouth
0.5
11.9
153
2477
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
3.5
11.8
55
164
SAA01
NOMESCO Finland
Simple examination of mouth
0.6
11.8
195
2954
J01MA12
ATC
levofloxacin; systemic
1.9
11.7
179
1017
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
0.4
11.5
55
1231
C77.1
ICD-10 Finland
Secondary and unspecified malignant neoplasm: Intrathoracic lymph nodes
+∞
11.5
11
*
C79.3
ICD-10 Finland
Secondary malignant neoplasm of brain and cerebral meninges
+∞
11.5
11
*
A04AA03
ATC
tropisetron; systemic
+∞
11.5
11
*
8120/3-C67.9
ICD-O-3
Transitional cell carcinoma, NOS, of bladder, NOS
+∞
11.5
11
*
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
121.4
11.4
12
*
ZX120
NOMESCO Finland
Intravenous
2.8
11.3
74
280
SPAT1312
SPAT
General health counselling
0.4
11.3
68
1399
EB1AA
NOMESCO Finland
Tooth X-ray examination
0.5
11.2
133
2211
R03AL06
ATC
olodaterol and tiotropium bromide; inhalant
5.2
11.2
34
68
NK6AN
NOMESCO Finland
Total body bone isotope imaging
20.3
11.1
16
8
WW200
SPAT
NA
0.0
11.1
*
303
SFA20
NOMESCO Finland
Filling on two surfaces of tooth
0.5
11.0
128
2143
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
0.6
11.0
169
2618
J01DB01
ATC
cefalexin; oral
0.6
11.0
379
4850
I25.1
ICD-10 Finland
Atherosclerotic heart disease
0.6
10.9
155
2456
JN5DR
NOMESCO Finland
PET-CT of upper body metabolism
43.8
10.9
13
*
1240
FHL
Bronchoscopy
4.9
10.5
33
69
L01CE01
ATC
topotecan; systemic
+∞
10.4
10
*
WF099
NOMESCO Finland
Other radiotherapy
+∞
10.4
10
*
115
Kela drug reimbursment
Breast cancer
+∞
10.4
10
*
L02BB03
ATC
bicalutamide; oral
+∞
10.4
10
*
C34.35
ICD-10 Finland
Malignant tumor of the lower lobe, bronchus or lung other non-microcellular carcinoma
+∞
10.4
10
*
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
0.5
10.4
88
1620
SPAT1053
SPAT
Memory test
0.4
10.4
46
1064
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
0.6
10.3
154
2416
H25.1
ICD-10 Finland
Senile nuclear cataract
0.5
10.3
132
2154
GA4YT
NOMESCO Finland
Puncture of pleura with ultrasound guidance
4.0
10.2
40
104
2391A
ICD-9 Finland
Neoplasm of unspecified nature, Respiratory system
14.8
10.0
16
11
J01MA14
ATC
moxifloxacin; systemic
2.4
9.8
87
390
GEA00
NOMESCO Finland
Mediastinoscopy
20.3
9.8
14
7
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.6
9.6
327
2358
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
0.5
9.5
60
1219
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
0.4
9.5
39
930
SPAT1043
SPAT
Audiometry
0.2
9.4
14
536
C10AA05
ATC
atorvastatin; oral
0.6
9.4
169
2542
C34.81
ICD-10 Finland
Malignant overall tumor of bronchial and pulmonary epidermoid carcinoma
+∞
9.4
9
*
1622B
ICD-9 Finland
Malignant neoplasm of trachea, bronchus and lung, Main bronchus[NEOPL MAL BRONCH PRINCIP,CA MICROCELLURE]
+∞
9.4
9
*
C34.29
ICD-10 Finland
Malignant tumor of the middle lobe, bronchus or lung other or unspecified histology
+∞
9.4
9
*
SPAT1325
SPAT
Vaccination
0.6
9.3
124
2008
I50.0
ICD-10 Finland
Congestive heart failure
0.4
9.1
33
825
N02BE01
ATC
paracetamol; systemic, rectal
0.6
9.1
440
5349
G04CA52
ATC
tamsulosin and dutasteride; systemic
0.4
9.0
30
781
SDA03
NOMESCO Finland
Demanding parodonthologic therapy
0.5
9.0
61
1212
351
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
0.4
9.0
33
823
SFA30
NOMESCO Finland
Filling on tree or more surfaces of tooth
0.5
8.9
90
1579
XG470
NOMESCO Finland
Measurement of diffusion capastity of the lungs
3.7
8.7
36
99
TGA30
NOMESCO Finland
Thoracocentesis
7.7
8.7
19
25
F17.29
ICD-10 Finland
Addiction caused by tobacco UNS
5.9
8.6
23
40
SPAT1256
SPAT
Intramuscular and subcutaneous injection
0.6
8.6
135
2103
M25.5
ICD-10 Finland
Pain in joint
0.4
8.6
48
1022
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
6.5
8.5
21
33
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
27.8
8.5
11
*
A79
ICPC
Malignancy NOS
27.8
8.5
11
*
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
0.4
8.5
27
714
G04CB01
ATC
finasteride; oral (testosterone-5-alpha reductase inhibitors)
0.5
8.4
66
1253
GCA32
NOMESCO Finland
Endoscopic insertion of stent into bronch
90.8
8.4
9
*
N05AX08
ATC
risperidone; systemic
0.3
8.4
19
591
NGB20
NOMESCO Finland
Primary total prosthetic replacement of knee joint without patellar part
0.3
8.4
14
504
ZX013
NOMESCO Finland
Radiotherapy with large shaped fields - SSD therapy
+∞
8.3
8
*
WD305
NOMESCO Finland
Simple therapy of methastized malignancy with biomodifiers
+∞
8.3
8
*
GDC01
NOMESCO Finland
Thoracoscopic lobectomy of lung
+∞
8.3
8
*
PJA12
NOMESCO Finland
Sentinel node biopsy
+∞
8.3
8
*
YL1BD
NOMESCO Finland
Extensive CT examination of pelvis for dose design of radiotherapy
+∞
8.3
8
*
1624B
ICD-9 Finland
Malignant neoplasm of trachea, bronchus and lung, Middle lobe, bronchus or lung[NEOPL MAL LOBI MEDII PULMONIS,CA MICROCELLURE]
+∞
8.3
8
*
1623X
ICD-9 Finland
Malignant neoplasm of trachea, bronchus and lung, Upper lobe, bronchus or lung[NEOPL MAL LOB SUPER PULMONIS,EI HIST/SYTOL DG]
+∞
8.3
8
*
I50.9
ICD-10 Finland
Heart failure, unspecified
0.5
8.3
86
1502
G04CB02
ATC
dutasteride; oral
0.3
8.2
17
547
SFA10
NOMESCO Finland
Fillning on one surface of tooth
0.6
8.1
132
2043
Z02.4
ICD-10 Finland
Examination for driving licence
0.5
8.1
86
1492
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
0.5
8.1
97
1624
B02AA02
ATC
tranexamic acid; systemic
2.2
8.0
80
380
TGD04
NOMESCO Finland
Needle biopsy of the lungs in bronchoscopy
13.2
7.9
13
10
M17.1
ICD-10 Finland
Other primary gonarthrosis
0.5
7.9
55
1082
J38.0
ICD-10 Finland
Paralysis of vocal cords and larynx
5.8
7.9
21
37
GDC00
NOMESCO Finland
Lobectomy of lung
45.3
7.7
9
*
C67.9
ICD-10 Finland
Malignant neoplasm: Bladder, unspecified
45.3
7.7
9
*
KE1BE
NOMESCO Finland
Rectal ultrasound examinaiton of prostata
0.3
7.7
13
465
G30.9
ICD-10 Finland
Alzheimer disease, unspecified
0.2
7.7
8
377
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
0.5
7.7
79
1384
M01AH05
ATC
etoricoxib; oral
0.6
7.6
178
2545
D38.3
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Mediastinum
18.5
7.6
11
6
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
2.7
7.6
49
186
J01FA06
ATC
roxithromycin; oral
1.5
7.4
301
2234
8500/3-C50.9
ICD-O-3
Infiltrating duct carcinoma, NOS, of breast, NOS
80.7
7.4
8
*
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
0.5
7.4
54
1049
R59.0
ICD-10 Finland
Localized enlarged lymph nodes
5.0
7.3
22
45
C64.88
ICD-10 Finland
Other malignant neoplasm of kidney, except renal pelvis
+∞
7.3
7
*
166
Kela drug reimbursment
Dalteparin and tinzaparin (treatment for more than 6 months)
+∞
7.3
7
*
C50.99
ICD-10 Finland
Breast, unspecified
+∞
7.3
7
*
C34
ICD-10 Finland
Malignant neoplasm of bronchus and lung
+∞
7.3
7
*
C34.92
ICD-10 Finland
Malignant tumor in unspecified localization in bronchial and pulmonary adenocarcinoma
+∞
7.3
7
*
C79.39
ICD-10 Finland
Secondary malignant tumor of the meninges, ventricle or other part of the brain
+∞
7.3
7
*
WB111
NOMESCO Finland
Multiple neoadjuvant cytostatic therapy
+∞
7.3
7
*
C34.91
ICD-10 Finland
Malignant tumor in unspecified localization in bronchial and pulmonary epidermoid carcinoma
+∞
7.3
7
*
C77.0
ICD-10 Finland
Secondary and unspecified malignant neoplasm: Lymph nodes of head, face and neck
+∞
7.3
7
*
J70.0
ICD-10 Finland
Acute pulmonary manifestations due to radiation
+∞
7.3
7
*
Z01.2
ICD-10 Finland
Dental examination
0.5
7.3
83
1414
GA1AE
NOMESCO Finland
Ultrasound examination of thorax
4.3
7.3
25
59
ZX050
NOMESCO Finland
Stereotactic radiotherapy
30.2
7.2
9
*
K02.1
ICD-10 Finland
Caries of dentine
0.6
7.1
145
2142
K03.82
ICD-10 Finland
Split tooth for reasons other than trauma
0.0
7.0
*
203
R04.2
ICD-10 Finland
Haemoptysis
2.7
7.0
45
171
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
1.8
7.0
129
777
H91.1
ICD-10 Finland
Presbycusis
0.3
6.9
11
406
SDA02
NOMESCO Finland
Parodonthologic therapy
0.5
6.9
60
1104
M17.0
ICD-10 Finland
Primary gonarthrosis, bilateral
0.4
6.8
28
667
HA6AA
NOMESCO Finland
Extra corporeal mammography of operated mammary gland
40.3
6.8
8
*
H02
ICPC
Hearing complaint
0.4
6.8
26
636
M05BX04
ATC
denosumab; parenteral
3.5
6.7
29
84
C09CA01
ATC
losartan; oral
0.6
6.7
85
1407
JN6AD
NOMESCO Finland
CT of torso and neck
22.7
6.7
9
*
C10AA07
ATC
rosuvastatin; oral
0.5
6.6
72
1246
Z72.0
ICD-10 Finland
Tobacco use
4.6
6.6
21
46
G04BD12
ATC
mirabegron; oral
0.3
6.6
12
412
Z25.8
ICD-10 Finland
Need for immunization against other specified single viral diseases
0.2
6.6
7
322
F01.9
ICD-10 Finland
Vascular dementia, unspecified
0.0
6.5
*
164
FN2BA
NOMESCO Finland
Percutaneous transluminal coronary angioplasty with stent (includes balloon pre-dilation)
0.2
6.5
6
305
SPAT1033
SPAT
Irrigation or wax removal of outer auditory canal
0.5
6.5
67
1172
ZXA10
NOMESCO Finland
Bilateral
0.5
6.4
51
969
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.3
6.4
57
257
WD325
NOMESCO Finland
Demanding therapy of methastized malignancy with biomodifiers
70.3
6.4
7
*
M79.6
ICD-10 Finland
Pain in limb
0.6
6.4
96
1528
I21.9
ICD-10 Finland
Acute myocardial infarction, unspecified
0.2
6.4
7
321
C09CA06
ATC
candesartan; oral
0.5
6.4
49
936
L17
ICPC
Foot/toe symptom/complaint
0.5
6.3
65
1143
N03AX14
ATC
levetiracetam; systemic
3.5
6.3
27
78
N06DA03
ATC
rivastigmine; oral, transdermal
0.2
6.3
8
337
KCD02
NOMESCO Finland
Transurethral resection of bladder
9.3
6.3
12
13
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
0.4
6.3
21
546
WX734
NOMESCO Finland
JET-ventilation
+∞
6.3
6
*
GD004
NOMESCO Finland
Palliative radiotherapy of trachea, bronchi and lungs
+∞
6.3
6
*
C32.0
ICD-10 Finland
Malignant neoplasm: Glottis
+∞
6.3
6
*
XZZ00
NOMESCO Finland
Active surveillance of a diagnosed cancer
+∞
6.3
6
*
1629B
ICD-9 Finland
Malignant neoplasm of trachea, bronchus and lung, Bronchus and lung, unspecified[NEOPL MAL PULMONIS LOCO ALIO/NUD,CA MICROCELLURE]
+∞
6.3
6
*
C34.31
ICD-10 Finland
Malignant tumor of the lower lobe, bronchus or lung epidermoid carcinoma
+∞
6.3
6
*
C80.90
ICD-10 Finland
Malignant tumor without specified localization without histology
+∞
6.3
6
*
C78.2
ICD-10 Finland
Secondary malignant neoplasm of pleura
+∞
6.3
6
*
YN7BD
NOMESCO Finland
Extensive CT examination of spine for dose design of radiotherapy
+∞
6.3
6
*
1629X
ICD-9 Finland
Malignant neoplasm of trachea, bronchus and lung, Bronchus and lung, unspecified[NEOPL MAL PULMONIS LOCO ALIO/NUD,EI HIST/SYTOL DG]
+∞
6.3
6
*
C34.82
ICD-10 Finland
Malignant overall tumor of bronchial and pulmonary adenocarcinoma
+∞
6.3
6
*
C38.4
ICD-10 Finland
Malignant neoplasm: Pleura
+∞
6.3
6
*
C34.01
ICD-10 Finland
Malignant tumor of the main bronchial epidermoid carcinoma
+∞
6.3
6
*
SPAT1310
SPAT
Counselling related to known health issue
0.6
6.2
91
1455
A07AA02
ATC
nystatin; oral
2.4
6.1
50
218
F00.10*G30.1
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, senile onset without additional symptoms
0.2
6.1
*
251
SPAT1301
SPAT
No procedures
0.6
6.1
112
1699
OAB73
NOMESCO Finland
Prevention and treatment of malnutrition
12.6
6.1
10
8
SAD01
NOMESCO Finland
Assessment of need for oral health care, standard
0.2
6.0
8
327
KMAK
NOMESCO Finland
NA
0.6
6.0
138
1993
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
0.6
6.0
156
2199

Mortality – FinRegistry

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

Index endpoint: C3_SCLC_EXALLC – Small cell lung cancer, excluding all cancers (controls excluding all cancers)

GWS hits: 1

This endpoint is excluded (different definition than used in FinnGen).