Appendicitis, broad definition

APPENDICITIS_BROAD

appendicitis: Acute inflammation of the vermiform appendix.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries None

0

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Check pre-conditions, main-only, mode, ICD version None

0

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Check minimum number of events None

0

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Include endpoints

25065

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APPENDICITIS_BROAD

Extra metadata

First used in FinnGen datafreeze DF3

Summary Statistics

Key figures

All Female Male
Number of individuals 24365 13274 11091
Unadjusted prevalence (%) 7.90 7.65 8.21
Mean age at first event (years) 33.94 32.22 36.00

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.01 1.03 [0.87, 1.23] 7.2e-1 1304
15 years 0.00 0.78 [0.67, 0.91] 2.1e-3 590
5 years 0.00 1.10 [0.92, 1.31] 3.1e-1 193
1 year 0.00 1.95 [1.47, 2.58] 3.2e-6 62

Correlations

Index endpoint: APPENDICITIS_BROAD – Appendicitis, broad definition
GWS hits: 7

Survival analyses between endpoints

Plot

before Appendicitis, broad definition
after Appendicitis, broad definition

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Drugs most likely to be purchased after Appendicitis, broad definition