Cholelithiasis, broad definition with cholecystitis

CHOLELITH_BROAD

cholelithiasis: The presence of calculi in the gallbladder.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries None

0

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Check pre-conditions, main-only, mode, ICD version None

0

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Check minimum number of events None

0

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Include endpoints

31035

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CHOLELITH_BROAD

Extra metadata

First used in FinnGen datafreeze DF3

Summary Statistics

Key figures

All Female Male
Number of individuals 30015 20289 9726
Unadjusted prevalence (%) 9.73 11.69 7.20
Mean age at first event (years) 51.86 48.56 58.73

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.55 [1.38, 1.74] 6.3e-14 3827
15 years 0.01 1.00 [0.90, 1.11] 9.9e-1 1716
5 years 0.00 1.61 [1.45, 1.79] 1.6e-18 821
1 year 0.00 4.79 [4.15, 5.53] <1e-100 468

Correlations

Index endpoint: CHOLELITH_BROAD – Cholelithiasis, broad definition with cholecystitis
GWS hits: 43

Survival analyses between endpoints

Plot

before Cholelithiasis, broad definition with cholecystitis
after Cholelithiasis, broad definition with cholecystitis

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Drugs most likely to be purchased after Cholelithiasis, broad definition with cholecystitis