Disorders of other endocrine glands

E4_ENDOGLAND

endocrine system disease: A disease involving the endocrine system.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Hospital Discharge: ICD-10 E20-E35
Cause of death: ICD-10 E20-E35

8923

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

8898

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Check minimum number of events None

8898

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E4_ENDOGLAND

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 11564 7929 3635
Unadjusted prevalence (%) 3.75 4.57 2.69
Mean age at first event (years) 48.85 47.79 51.16

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 2.14 [1.65, 2.78] 9.3e-9 1318
15 years 0.01 1.37 [1.11, 1.69] 3.2e-3 606
5 years 0.00 2.71 [2.31, 3.18] 4.5e-34 385
1 year 0.00 5.90 [4.80, 7.25] 9.3e-64 165

Cumulative Incidence

Correlations

Index endpoint: E4_ENDOGLAND – Disorders of other endocrine glands
GWS hits: 1

Survival analyses between endpoints

Plot

before Disorders of other endocrine glands
after Disorders of other endocrine glands

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Drugs most likely to be purchased after Disorders of other endocrine glands