hypopituitarism: A condition of diminution or cessation of secretion of one or more hormones from the anterior pituitary gland. This may result from surgical or radiation ablation, non-secretory pituitary neoplasms, metastatic tumors, infarction, pituitary apoplexy, infiltrative or granulomatous processes, and other conditions.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
3 out of 7 registries used, show all original rules. |
2764 |
4. Check minimum number of eventsNone |
2764 |
5. Include endpointsNone |
2764 |
6. Filter based on genotype QC (FinnGen only) |
2764 |
Control definitions (FinnGen only)
- Control exclude
- E4_ENDOGLAND
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
Similar endpoints
↥List of similar endpoints to
Hypopituitarism
based on the number of shared cases.
Similar with more cases:
- Disorders of other endocrine glands
- Endocrine, nutritional and metabolic diseases
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 15672 | 5905 | 9659 |
| Only index persons | 13551 | 5010 | 8541 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.23 | 0.17 | 0.27 |
| Only index persons | 0.27 | 0.18 | 0.33 |
| Median age at first event (years) | |||
| Whole population | 41.91 | 39.45 | 43.37 |
| Only index persons | 42.21 | 38.87 | 44.17 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 2764 | 1007 | 1757 |
| Unadjusted period prevalence (%) | 0.62 | 0.34 | 0.77 |
| Median age at first event (years) | 46.48 | 42.53 | 48.75 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 2457
- Matched controls
- 24550
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H01AC01
ATC
somatropin; parenteral
2333.7
323.0
373
*
E23.00
ICD-10 Finland
Panhypopituitarism
+∞
323.0
578
*
AA4CG
NOMESCO Finland
Extensive MRI examination of sella turcica with high intensity magnet
197.2
323.0
540
35
D35.2
ICD-10 Finland
Benign neoplasm: Pituitary gland
233.1
323.0
472
25
E23.05
ICD-10 Finland
Lack of TSH
1956.7
323.0
328
*
G03BA03
ATC
testosterone; systemic, rectal, sublingual, transdermal
31.0
323.0
1080
606
H02AB09
ATC
hydrocortisone; systemic
68.3
323.0
843
186
E23.04
ICD-10 Finland
Hypogonadotropic hypogonadism
448.8
323.0
908
32
H03AA01
ATC
levothyroxine sodium; systemic
8.5
323.0
1139
2274
101
Kela drug reimbursment
Anterior pituitary hypofunction
+∞
323.0
1042
*
AAE10
NOMESCO Finland
Transsphenoidal total or partial excision of intracranial lesion
292.5
284.4
285
11
E23.03
ICD-10 Finland
Lack of ACTH
+∞
254.6
240
*
E23.01
ICD-10 Finland
Isolated deficiency of growth hormone
+∞
243.8
230
*
102
Kela drug reimbursment
Diabetes insipidus
+∞
177.2
168
*
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
13.3
177.0
323
276
E23.06
ICD-10 Finland
Empty sella
+∞
161.2
153
*
186
Kela drug reimbursment
Growth retardation associated with renal failure (growth hormone)
+∞
145.2
138
*
301
Kela drug reimbursment
Growth hormone
1459.7
142.0
137
*
E23.09
ICD-10 Finland
Pituitary insufficiency NOS
+∞
136.7
130
*
E29.1
ICD-10 Finland
Testicular hypofunction
34.6
130.4
171
53
NK6MA
NOMESCO Finland
Measurement of bone age from hand and elbow using X-ray
17.4
125.8
203
126
E34.35
ICD-10 Finland
Abnormal growth retardation
431.9
124.9
124
*
E22.1
ICD-10 Finland
Hyperprolactinaemia
428.2
123.9
123
*
H01BA02
ATC
desmopressin; nasal, systemic, sublingual
11.7
119.3
229
213
D44.3
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Pituitary gland
594.8
116.0
114
*
121
Kela drug reimbursment
Severe hypofunction of sexual glands
23.5
110.7
161
73
N04BC06
ATC
cabergoline; oral (dopamine agonists)
170.5
109.2
114
7
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
4.7
108.2
404
978
AA4BG
NOMESCO Finland
MRI examination of sella turcica with high intensity magnet
145.1
105.0
111
8
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
4.7
104.4
394
962
E23.2
ICD-10 Finland
Diabetes insipidus
+∞
101.7
97
*
E27.4
ICD-10 Finland
Other and unspecified adrenocortical insufficiency
996.4
98.7
96
*
E23.02
ICD-10 Finland
Neurosecretory dysfunction of the growth hormone
+∞
97.5
93
*
E34.39
ICD-10 Finland
Short stature, not elsewhere classified
496.5
97.1
96
*
AA4CM
NOMESCO Finland
Extensive MRI examination of sella turcica with 3 Tesla magnet
491.1
96.0
95
*
Y28
ICPC
Limited function/disability (Y)
48.1
94.3
115
25
G47.3
ICD-10 Finland
Sleep apnoea
2.7
80.8
700
3182
AA4DG
NOMESCO Finland
Very extensive MRI examination of sella turcica with high intensity magnet
193.1
72.5
75
*
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.8
72.1
545
2259
E27.3
ICD-10 Finland
Drug-induced adrenocortical insufficiency
686.2
68.3
67
*
E27.1
ICD-10 Finland
Primary adrenocortical insufficiency
+∞
68.0
65
*
XCK00
NOMESCO Finland
Perimetry
4.7
67.7
247
570
N06AX16
ATC
venlafaxine; oral
3.0
65.9
439
1666
E23.08
ICD-10 Finland
Hypopituitarism
+∞
64.8
62
*
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
6.3
64.6
180
303
H53.4
ICD-10 Finland
Visual field defects
9.1
64.2
139
160
N06AX11
ATC
mirtazapine; oral
2.3
63.0
783
4197
SPAT1256
SPAT
Intramuscular and subcutaneous injection
2.1
62.2
1035
6311
T99
ICPC
Endocr/metab/nutrit disease other
12.0
60.5
113
98
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
4.8
59.8
214
483
ZXC86
NOMESCO Finland
Use of endoscopic device
22.5
59.5
87
40
D35.30
ICD-10 Finland
Craniopharyngoma
+∞
58.5
56
*
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
6.6
58.2
157
253
E89.30
ICD-10 Finland
Postprocedural hypopituitarism
+∞
56.4
54
*
2273A
ICD-9 Finland
Benign neoplasm of other endocrine glands and related structures, Pituitary gland and craniopharyngeal duct (pouch)
559.9
55.8
55
*
E34.9
ICD-10 Finland
Endocrine disorder, unspecified
559.9
55.8
55
*
E22.0
ICD-10 Finland
Acromegaly and pituitary gigantism
+∞
55.4
53
*
E23.0
ICD-10 Finland
Hypopituitarism
+∞
55.4
53
*
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.3
55.1
627
3186
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.0
52.9
1008
6367
E23
ICD-10 Finland
Hypofunction and other disorders of pituitary gland
+∞
52.2
50
*
N05BA04
ATC
oxazepam; oral
2.3
52.2
591
2986
N06AX21
ATC
duloxetine; oral
3.1
51.7
317
1125
E34.30
ICD-10 Finland
Short stature NOS
+∞
51.2
49
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.2
50.9
666
3586
N06AB10
ATC
escitalopram; oral
2.3
50.7
545
2679
R53
ICD-10 Finland
Malaise and fatigue
2.4
50.3
510
2435
N05AH04
ATC
quetiapine; oral
2.4
49.6
485
2272
N03AX16
ATC
pregabalin; oral
2.2
47.6
557
2838
N03AX12
ATC
gabapentin; oral
2.6
47.5
388
1645
N06AB04
ATC
citalopram; systemic
2.3
46.4
498
2435
A55
ICPC
General and Unspecified, Local injection/infiltration
15.2
46.1
77
52
E23.6
ICD-10 Finland
Other disorders of pituitary gland
+∞
46.0
44
*
105
Kela drug reimbursment
Adrenal cortical hypofunction
+∞
44.9
43
*
A02BC02
ATC
pantoprazole; systemic
1.8
44.2
1381
10154
Z01.8
ICD-10 Finland
Other specified special examinations
2.2
44.2
554
2899
G02CB01
ATC
bromocriptine; systemic
11.1
43.1
83
77
AA1AD
NOMESCO Finland
CT of head and brain
2.2
43.0
539
2818
R06.0
ICD-10 Finland
Dyspnoea
2.1
42.4
550
2918
R51.80
ICD-10 Finland
Headache
2.4
42.4
428
2020
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
3.0
41.8
268
975
2542
FHL
Transasal hypophysectomy
+∞
41.8
40
*
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.5
41.3
357
1554
E34.31
ICD-10 Finland
Short stature, prenatal disorder
+∞
40.7
39
*
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.5
40.6
363
1607
N02AX02
ATC
tramadol; systemic, rectal
1.8
40.4
932
6133
A50
ICPC
General and Unspecified, Medication/prescr/renewal
4.9
39.5
135
289
R5140
NOMESCO Finland
Monitoring the use of the aid
2.6
39.2
315
1311
AAB10
NOMESCO Finland
Partial excision of intracranial lesion
10.1
37.8
76
77
H47.2
ICD-10 Finland
Optic atrophy
23.0
37.5
54
24
N05CF01
ATC
zopiclone; oral
1.9
37.2
661
3944
D35.31
ICD-10 Finland
Cyst in Rathke's pocket
45.7
36.9
45
10
N02AA05
ATC
oxycodone; systemic
2.5
36.9
307
1302
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.1
36.2
476
2518
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
2.7
35.8
264
1044
E66.8
ICD-10 Finland
Other obesity
3.6
35.6
167
482
E66.01
ICD-10 Finland
Obesity due to excess calories
2.9
34.8
232
861
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.0
34.7
501
2750
9350/1-C75.2
ICD-O-3
Craniopharyngioma, NOS, of craniopharyngeal duct
+∞
34.4
33
*
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
3.0
34.3
211
743
-50
ICPC
Medication/prescr/renewal
4.3
33.9
131
318
N03AE01
ATC
clonazepam; systemic
3.3
33.5
178
566
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.9
33.2
598
3563
E03.89
ICD-10 Finland
Other specified hypothyroidism
5.1
32.9
107
217
N05BA01
ATC
diazepam; systemic, rectal
2.3
32.4
324
1507
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.4
32.4
304
1371
E27.2
ICD-10 Finland
Addisonian crisis
+∞
32.3
31
*
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.7
32.3
230
889
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
3.2
32.2
177
577
WX408
NOMESCO Finland
General anesthesy, balanced
1.8
32.2
677
4244
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.6
32.1
258
1070
N03AX09
ATC
lamotrigine; oral
3.4
32.0
164
507
N06AA09
ATC
amitriptyline; systemic
2.8
32.0
225
864
G03GA01
ATC
chorionic gonadotrophin; parenteral
4.8
31.5
109
237
N91.1
ICD-10 Finland
Secondary amenorrhoea
7.9
31.5
73
95
2532A
ICD-9 Finland
Disorders of the pituitary gland and its hypothalamic control, Panhypopituitarism[PANHYPOPITUITARISMUS]
+∞
31.3
30
*
G02CB03
ATC
cabergoline; oral (prolactine inhibitors)
32.0
31.3
41
13
N06AX26
ATC
vortioxetine; oral
3.0
31.3
190
664
E21.09
ICD-10 Finland
Other primary hyperparathyroidism
161.9
30.7
32
*
N05CD07
ATC
temazepam; oral
2.5
30.7
255
1076
N02BE01
ATC
paracetamol; systemic, rectal
1.7
30.6
1873
15917
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.7
30.2
1021
7356
T28
ICPC
Limited function/disability (T)
10.0
29.9
60
61
N06AX12
ATC
bupropion; oral
2.8
29.6
198
736
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
3.4
29.6
149
455
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
3.2
29.3
165
544
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.2
29.0
339
1691
J45.9
ICD-10 Finland
Asthma, unspecified
2.0
28.9
405
2181
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
2.5
28.8
241
1021
A02BC05
ATC
esomeprazole; systemic
1.7
28.8
838
5764
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.6
28.6
230
953
104
Kela drug reimbursment
Thyroid insufficiency
3.3
28.5
148
463
AA1DM
NOMESCO Finland
Very extensive MRI examination of brain with 3 Tesla magnet
10.4
28.4
56
55
E24.0
ICD-10 Finland
Pituitary-dependent Cushing disease
+∞
28.2
27
*
SPAT1254
SPAT
Administration of medicine
2.1
28.0
355
1831
H02AA02
ATC
fludrocortisone; oral
17.2
27.9
44
26
E66.00
ICD-10 Finland
Metabolic syndrome
3.1
27.3
161
550
N05BA12
ATC
alprazolam; oral
2.4
27.3
238
1031
2370A
ICD-9 Finland
Neoplasm of uncertain behaviour of endocrine glands and nervous system, Pituitary gland and craniopharyngeal duct
+∞
27.1
26
*
22620
ICD-8 Finland
Benign neoplasm of endocrine glands, Pituitary gland and craniopharyngeal duct (pouch)
+∞
27.1
26
*
R50.9
ICD-10 Finland
Fever, unspecified
2.0
27.0
383
2065
E23.7
ICD-10 Finland
Disorder of pituitary gland, unspecified
273.7
26.8
27
*
J01FF01
ATC
clindamycin; systemic
1.8
26.6
591
3733
A06AC01
ATC
ispaghula (psylla seeds); oral
1.9
26.2
447
2582
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.0
26.0
392
2164
CS434
NOMESCO Finland
Visual field testing with Humphrey automated perimetry
5.9
25.7
73
127
AAB00
NOMESCO Finland
Extirpation of intracranial lesion
7.2
25.4
62
88
I10
ICD-10 Finland
Essential (primary) hypertension
1.6
25.0
1036
7744
TAB00
NOMESCO Finland
Lumbar puncture
3.0
24.8
148
511
SPAT1263
SPAT
Sampling
1.6
24.8
920
6691
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.3
24.6
238
1082
E29.9
ICD-10 Finland
Testicular dysfunction, unspecified
43.3
24.6
30
7
SPAT1262
SPAT
Handing over of treatment supplies
1.9
24.5
397
2246
CS424
NOMESCO Finland
Visual field testing with Goldmann perimetry
8.7
24.5
53
62
M05BA04
ATC
alendronic acid; oral
3.2
24.3
131
421
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.6
24.3
761
5285
N05CF02
ATC
zolpidem; oral
1.9
24.1
376
2098
C07AB07
ATC
bisoprolol; oral
1.6
24.1
840
5996
R52.2
ICD-10 Finland
Other chronic pain
4.0
23.8
99
258
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.7
23.8
701
4781
D32.00
ICD-10 Finland
Benign tumor of the meninges on the outer surface of the cerebrum
8.6
23.5
51
60
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
2.9
23.5
152
553
N06AB06
ATC
sertraline; oral
2.2
23.5
269
1325
C07AA05
ATC
propranolol; systemic
1.8
23.5
423
2483
ZXC95
NOMESCO Finland
Use of surgical navigator
7.4
23.5
56
77
N03AG01
ATC
valproic acid; systemic, rectal
2.6
23.4
177
707
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
2.6
23.4
174
689
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.8
23.2
424
2498
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.0
23.1
342
1869
G44.2
ICD-10 Finland
Tension-type headache
2.1
23.0
283
1436
M03BX02
ATC
tizanidine; oral
1.5
23.0
1337
10749
H02AB06
ATC
prednisolone; systemic
1.6
23.0
961
7155
SPAT1249
SPAT
Treatment-related counselling outside office
1.6
22.8
856
6201
C03CA01
ATC
furosemide; systemic
1.8
22.7
438
2626
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.4
22.7
203
888
C08CA01
ATC
amlodipine; oral
1.7
22.7
633
4242
R07.4
ICD-10 Finland
Chest pain, unspecified
1.7
22.7
534
3407
CS494
NOMESCO Finland
Other visual field testing
5.0
22.7
73
148
A06AD11
ATC
lactulose; oral
2.2
22.6
258
1265
SPAT1153
SPAT
Removal of sutures
1.7
22.6
625
4177
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.9
22.6
342
1882
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.5
22.6
1210
9536
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.6
22.6
950
7075
SPAT1301
SPAT
No procedures
1.6
22.5
660
4485
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.4
22.3
202
888
J01DB01
ATC
cefalexin; oral
1.6
22.2
1880
16446
R42
ICD-10 Finland
Dizziness and giddiness
1.9
22.1
391
2275
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.8
22.0
454
2783
BF20A
NOMESCO Finland
NA
+∞
21.9
21
*
25320
ICD-8 Finland
Diseases of pituitary gland, Chromophobe adenoma, pituitary
+∞
21.9
21
*
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
2.0
21.9
320
1740
R03AC02
ATC
salbutamol; inhalant
1.5
21.8
1170
9193
N06AB03
ATC
fluoxetine; oral
2.1
21.7
277
1425
CS5Z4
NOMESCO Finland
Specialised imaging for glaucoma
5.2
21.4
67
132
M01AE03
ATC
ketoprofen; systemic, rectal
1.6
21.3
742
5256
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.0
21.3
277
1437
D32.02
ICD-10 Finland
Benign tumor of the meninges at the base of the brain
9.9
21.0
42
43
E23.3
ICD-10 Finland
Hypothalamic dysfunction, not elsewhere classified
+∞
20.9
20
*
E24.9
ICD-10 Finland
Cushing syndrome, unspecified
+∞
20.9
20
*
E30.09
ICD-10 Finland
Delayed puberty NOS
+∞
20.9
20
*
CS444
NOMESCO Finland
Visual field testing with Octopus automated perimetry
3.7
20.8
92
254
N02AJ06
ATC
codeine and paracetamol; systemic
1.6
20.7
792
5735
602
Kela drug reimbursment
Children's severe malnutrition
6.3
20.6
55
89
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.8
20.6
405
2439
N06AB05
ATC
paroxetine; oral
2.6
20.6
153
606
L28
ICPC
Limited function/disability (L)
2.0
20.6
273
1428
UJF32
NOMESCO Finland
Coloscopy
1.7
20.5
491
3139
E03.80
ICD-10 Finland
Hypothyroidism caused by autoimmune thyroiditis
4.9
20.0
66
138
J01MA12
ATC
levofloxacin; systemic
1.8
19.9
351
2037
NA2AA
NOMESCO Finland
Thoracal spine X-ray examination without contrast
4.1
19.9
78
194
25310
ICD-8 Finland
Diseases of pituitary gland, Panhypopituitarismus
+∞
19.8
19
*
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.6
19.8
741
5323
WX110
NOMESCO Finland
Local anesthesy
1.5
19.8
1602
13630
F34.1
ICD-10 Finland
Dysthymia
3.3
19.7
101
314
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.7
19.7
464
2951
R06.5
ICD-10 Finland
Mouth breathing
2.1
19.6
249
1278
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
1.9
19.5
312
1749
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
2.3
19.4
192
884
WX723
NOMESCO Finland
CPAP therapy
3.1
19.1
109
366
N05BE01
ATC
buspirone; oral
3.4
19.0
92
274
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
2.1
19.0
215
1051
F32.11
ICD-10 Finland
Moderate depressive episode with somatic syndrome
3.5
18.9
89
259
M54.5
ICD-10 Finland
Low back pain
1.6
18.8
687
4896
E89.39
ICD-10 Finland
Postprocedural hypopituitarism, other or several procedures
+∞
18.8
18
*
E27.9
ICD-10 Finland
Disorder of adrenal gland, unspecified
+∞
18.8
18
*
E23.1
ICD-10 Finland
Drug-induced hypopituitarism
+∞
18.8
18
*
E22.80
ICD-10 Finland
Central precocious puberty
+∞
18.8
18
*
A02BC01
ATC
omeprazole; systemic
1.6
18.7
519
3449
Z51.80
ICD-10 Finland
Manipulation of puberty development with hormone therapy
191.2
18.5
19
*
SPAT1310
SPAT
Counselling related to known health issue
1.6
18.5
673
4791
EP1AE
NOMESCO Finland
Neck ultrasound examination
2.7
18.4
129
493
RD210
NOMESCO Finland
NA
3.4
18.2
90
273
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.1
18.1
222
1122
F33.11
ICD-10 Finland
Recurrent depression, moderate episode of somatic syndrome
3.8
18.1
77
207
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
2.2
18.0
185
868
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
2.9
17.9
113
406
N02CC01
ATC
sumatriptan; nasal, systemic, rectal
1.9
17.7
278
1546
2530A
ICD-9 Finland
Disorders of the pituitary gland and its hypothalamic control, Acromegaly and gigantism[ACROMEGALIA]
+∞
17.7
17
*
XCW99
NOMESCO Finland
Other investigative procedure of eye
2.1
17.7
219
1111
R11
ICD-10 Finland
Nausea and vomiting
2.2
17.7
183
859
M79.6
ICD-10 Finland
Pain in limb
1.5
17.7
701
5077
XA800
NOMESCO Finland
Neuropsychological investigation
2.4
17.7
153
657
J01AA02
ATC
doxycycline; systemic
1.5
17.6
1577
13515
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.6
17.5
615
4328
Z01.1
ICD-10 Finland
Examination of ears and hearing
1.8
17.4
312
1816
R01AD08
ATC
fluticasone; nasal
1.6
17.3
586
4085
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
2.1
17.2
211
1067
SPAT1216
SPAT
Assessment of functional ability
1.9
17.1
273
1525
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.9
17.1
269
1498
A10BA02
ATC
metformin; oral
1.6
16.9
493
3305
A02BC03
ATC
lansoprazole; oral
1.6
16.8
527
3601
Z31.5
ICD-10 Finland
Genetic counselling
2.5
16.8
136
566
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.9
16.7
257
1420
Y08
ICPC
Sexual function sympt/compl male
10.4
16.7
32
31
N05AA02
ATC
levomepromazine; systemic
2.7
16.6
112
421
E22.9
ICD-10 Finland
Hyperfunction of pituitary gland, unspecified
170.9
16.5
17
*
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
2.3
16.4
153
682
R01AD09
ATC
mometasone; nasal
1.4
16.3
951
7447
A41.9
ICD-10 Finland
Sepsis, unspecified
3.0
16.2
95
326
D64.9
ICD-10 Finland
Anaemia, unspecified
2.2
16.2
175
838
D75.1
ICD-10 Finland
Secondary polycythaemia
10.4
16.2
31
30
H04.10
ICD-10 Finland
Dry eye syndrome
2.1
16.1
181
881
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
3.7
16.1
70
192
SPAT1203
SPAT
Injection therapy, other than intramuscular or subcutaneous
3.1
16.0
91
303
A04
ICPC
Weakness/tiredness general
1.9
15.9
257
1442
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.6
15.8
436
2878
ZX114
NOMESCO Finland
Intramuscular
4.3
15.8
59
141
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.7
15.8
396
2548
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.6
15.8
470
3162
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
2.9
15.8
97
343
M48.0
ICD-10 Finland
Spinal stenosis
2.1
15.8
194
980
T29
ICPC
Endocr/metab/nutr sympt/compl other
4.2
15.8
60
146
N06AG02
ATC
moclobemide; oral
2.7
15.8
106
397
7834C
ICD-9 Finland
Symptoms concerning nutrition, metabolism and development, Lack of expected normal physiological development[HÄIRIINTYNYT PITUUSKASVU]
60.3
15.8
18
*
SAA03
NOMESCO Finland
Extended examination of mouth
1.4
15.7
921
7204
M81.9
ICD-10 Finland
Osteoporosis, unspecified
3.9
15.7
64
166
SPAT1240
SPAT
Therapeutic discussion
1.9
15.7
254
1427
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.5
15.7
613
4407
Q87.16
ICD-10 Finland
Mulibrey nanism
+∞
15.6
15
*
103
Kela drug reimbursment
Diabetes, insulin-treated
1.6
15.6
503
3453
E03
ICD-10 Finland
Other hypothyroidism
2.8
15.5
104
388
H49.0
ICD-10 Finland
Third [oculomotor] nerve palsy
11.8
15.5
28
24
TPH04
NOMESCO Finland
Cathetrisation of vein
1.6
15.5
415
2714
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
2.7
15.5
105
396
H01CB03
ATC
lanreotide; parenteral
38.3
15.4
19
5
M54.4
ICD-10 Finland
Lumbago with sciatica
1.7
15.4
318
1932
ZXA10
NOMESCO Finland
Bilateral
1.7
15.2
361
2286
SPAT1229
SPAT
Assessment of need for aid
2.4
15.2
135
590
F31.30
ICD-10 Finland
Bipolar disorder Depressive episode without somatic syndrome
4.0
15.2
60
152
R60.0
ICD-10 Finland
Localized oedema
2.0
15.2
196
1013
E21.0
ICD-10 Finland
Primary hyperparathyroidism
45.2
15.1
18
*
SPAT1260
SPAT
Consultation of another employee
1.7
15.1
347
2177
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
3.1
15.0
84
280
C03DA01
ATC
spironolactone; oral
2.1
15.0
182
915
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.5
15.0
619
4494
J01MA02
ATC
ciprofloxacin; systemic
1.5
14.9
725
5447
ZX120
NOMESCO Finland
Intravenous
2.0
14.9
202
1063
UDQ12
NOMESCO Finland
Flexible laryngoscopy
2.4
14.9
127
543
C08CA13
ATC
lercanidipine; oral
1.9
14.9
218
1182
J01CA04
ATC
amoxicillin; systemic
1.5
14.9
1879
16897
UDC00
NOMESCO Finland
Ear microscopy
2.1
14.9
168
822
XF400
NOMESCO Finland
ECG with 12 standard connections
1.7
14.8
350
2212
AA1AG
NOMESCO Finland
Short MRI examination of brain with median intensity magnet
4.4
14.8
53
122
WX722
NOMESCO Finland
PEEP
2.5
14.8
121
508
R03BA05
ATC
fluticasone; inhalant
1.6
14.7
397
2601
E0000UV
ATC
NA
1.4
14.7
815
6284
M25.5
ICD-10 Finland
Pain in joint
1.5
14.6
570
4085
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.6
14.6
474
3253
2594A
ICD-9 Finland
Other endocrine disorders, Dwarfism, not elsewhere classified
+∞
14.6
14
*
J05AB01
ATC
aciclovir; systemic
1.6
14.6
388
2535
G03DB01
ATC
dydrogesterone; oral
2.0
14.5
197
1035
F31.9
ICD-10 Finland
Bipolar affective disorder, unspecified
3.2
14.5
75
237
E89.6
ICD-10 Finland
Postprocedural adrenocortical(-medullary) hypofunction
150.7
14.5
15
*
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.8
14.4
253
1460
N03AF01
ATC
carbamazepine; oral, rectal
2.6
14.4
108
431
ABD30
NOMESCO Finland
Implantation of spinal stimulation device
6.9
14.4
35
51
C10AC01
ATC
colestyramine; oral
3.7
14.3
61
166
SPAT1312
SPAT
General health counselling
1.5
14.1
682
5105
N06AB08
ATC
fluvoxamine; oral
3.2
14.1
73
231
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.6
14.0
354
2275
M01AE02
ATC
naproxen; oral, rectal
1.4
14.0
1224
10229
R62.8
ICD-10 Finland
Other lack of expected normal physiological development
9.4
13.9
28
30
Y50
ICPC
Male Genital, Medication/prescr/renewal
30.2
13.9
18
6
P76
ICPC
Depressive disorder
2.2
13.9
144
678
A46
ICD-10 Finland
Erysipelas
1.8
13.8
261
1540
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
3.1
13.8
74
240
N46
ICD-10 Finland
Male infertility
3.6
13.8
62
176
D35.0
ICD-10 Finland
Benign neoplasm: Adrenal gland
4.5
13.8
48
108
E28.2
ICD-10 Finland
Polycystic ovarian syndrome
20.1
13.8
20
10
N05BA06
ATC
lorazepam; systemic, sublingual
2.6
13.7
102
407
T90
ICPC
Diabetes non-insulin dependent
1.6
13.7
398
2655
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
1.8
13.6
249
1452
N06AX22
ATC
agomelatine; oral
3.3
13.6
69
215
M03BC01
ATC
orphenadrine (citrate); systemic
1.5
13.6
488
3424
G03FB08
ATC
dydrogesterone and estrogen; systemic (progestogens and estrogens, sequential prep.)
2.8
13.6
89
329
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.5
13.6
555
4007
A03FA01
ATC
metoclopramide; systemic, rectal
1.6
13.6
339
2171
WVA30
SPAT
NA
3.1
13.6
73
238
E26.0
ICD-10 Finland
Primary hyperaldosteronism
+∞
13.5
13
*
J45.1
ICD-10 Finland
Nonallergic asthma
2.1
13.5
160
796
H01CB02
ATC
octreotide; parenteral
34.2
13.5
17
5
G93.2
ICD-10 Finland
Benign intracranial hypertension
16.3
13.4
21
13
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.9
13.4
194
1045
J01FA10
ATC
azithromycin; systemic
1.4
13.4
1291
10938
H02AB04
ATC
methylprednisolone; systemic
1.7
13.4
267
1604
M80.8
ICD-10 Finland
Other osteoporosis with pathological fracture
18.3
13.4
20
11
M02AA07
ATC
piroxicam; topical
1.5
13.3
636
4744
M01AH01
ATC
celecoxib; oral (coxibs)
1.7
13.3
318
2013
J02AC01
ATC
fluconazole; systemic
1.5
13.3
643
4807
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
1.9
13.3
197
1070
K03.66
ICD-10 Finland
Tooth plaque
2.0
13.3
183
968
NA2BG
NOMESCO Finland
Thoracal spine MRI examination with high intensity magnet
3.5
13.2
61
177
T50
ICPC
Metabolic, Medication/prescr/renewal
13.8
13.2
22
16
N06AX03
ATC
mianserin; oral
2.6
13.2
95
372
Z00.0
ICD-10 Finland
General medical examination
1.6
13.2
372
2462
F45.4
ICD-10 Finland
Persistent somatoform pain disorder
4.1
13.1
50
123
N06BA04
ATC
methylphenidate; oral
2.7
13.0
90
345
E66.9
ICD-10 Finland
Obesity, unspecified
2.8
13.0
82
298
E28.3
ICD-10 Finland
Primary ovarian failure
28.5
12.9
17
6
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
2.6
12.8
91
353
XX1ZW
NOMESCO Finland
Very extensive written report from radiologist
9.7
12.7
25
26
P06
ICPC
Sleep disturbance
1.8
12.7
209
1179
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
2.1
12.7
143
700
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.1
12.6
149
740
R03DC03
ATC
montelukast; oral
1.6
12.6
337
2194
F31.7
ICD-10 Finland
Bipolar affective disorder, currently in remission
3.6
12.6
57
163
R01BA52
ATC
pseudoephedrine, combinations; oral
1.5
12.6
560
4105
N03AX11
ATC
topiramate; oral
3.1
12.6
67
217
N06CA01
ATC
amitriptyline and psycholeptics; systemic
2.0
12.6
174
922
SAA04
NOMESCO Finland
Special inverstigation of mouth
2.1
12.6
149
745
R06AE07
ATC
cetirizine; oral
1.4
12.5
875
6986
C10AA05
ATC
atorvastatin; oral
1.4
12.5
623
4674
M54.9
ICD-10 Finland
Dorsalgia, unspecified
1.8
12.5
213
1216
25390
ICD-8 Finland
Diseases of pituitary gland, Diabetes insipidus
+∞
12.5
12
*
E89.31
ICD-10 Finland
Postirradiation hypopituitarism
+∞
12.5
12
*
G02CB04
ATC
quinagolide; oral
+∞
12.5
12
*
106
Kela drug reimbursment
Hypoparathyroidism
+∞
12.5
12
*
F32.00
ICD-10 Finland
Mild depressive episode without somatic syndrome
2.5
12.5
100
415
UDH02
NOMESCO Finland
Rhinopharyngoscopy
2.1
12.5
150
752
G91.1
ICD-10 Finland
Obstructive hydrocephalus
9.3
12.5
25
27
S18
ICPC
Laceration/cut
1.4
12.5
807
6360
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
1.7
12.5
257
1558
H05AA02
ATC
teriparatide; parenteral
130.5
12.4
13
*
AA1BD
NOMESCO Finland
Extensive CT of head and brain
3.6
12.4
56
160
UKC02
NOMESCO Finland
Cystoscopy
1.7
12.4
271
1670
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
1.9
12.4
192
1064
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.4
12.3
1181
9937
T36
ICD-10 Finland
Poisoning by systemic antibiotics
2.3
12.3
116
523
C09CA06
ATC
candesartan; oral
1.6
12.3
377
2546
UDM02
NOMESCO Finland
Sinoscopy
3.2
12.2
63
200
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
2.2
12.2
121
560
T55
ICPC
Metabolic, Local injection/infiltration
37.7
12.2
15
*
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.4
12.2
1029
8474
X59
ICD-10 Finland
Exposure to unspecified factor
1.5
12.2
414
2862
C09CA01
ATC
losartan; oral
1.5
12.1
397
2721
T82
ICPC
Obesity
2.6
12.1
87
339
C03EA01
ATC
hydrochlorothiazide and potassium-sparing agents; oral
1.8
12.1
208
1191
A02BA04
ATC
nizatidine; systemic
2.1
12.1
132
638
N06AA12
ATC
doxepin; systemic
2.4
12.0
101
431
N05AX08
ATC
risperidone; systemic
2.0
12.0
154
794
G03GA02
ATC
human menopausal gonadotrophin; parenteral
4.1
12.0
45
110
SPAT1292
SPAT
Other function in accordance with SHToL (Finnish classification of nursing interventions)
2.0
11.9
153
790
UGC12
NOMESCO Finland
Flexible bronchoscopy
2.1
11.9
137
674
M05BX04
ATC
denosumab; parenteral
3.0
11.9
69
237
A11CC03
ATC
alfacalcidol; systemic
3.5
11.9
55
161
R55
ICD-10 Finland
Syncope and collapse
1.8
11.8
193
1087
L17
ICPC
Foot/toe symptom/complaint
1.5
11.8
463
3304
L03
ICPC
Low back symptom/complaint
1.5
11.8
448
3171
E87.0
ICD-10 Finland
Hyperosmolality and hypernatraemia
11.7
11.8
21
18
R03BA08
ATC
ciclesonide; inhalant
2.0
11.8
158
830
Y99
ICPC
Genital disease male other
10.5
11.7
22
21
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.8
11.7
197
1120
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.8
11.7
211
1228
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
2.0
11.6
148
758
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
2.0
11.6
150
774
BBA30
NOMESCO Finland
Excision of lesion of parathyroid gland
65.2
11.6
13
*
N06AA06
ATC
trimipramine; systemic
3.3
11.6
57
175
N06AX05
ATC
trazodone; oral
3.3
11.6
57
175
F83
ICD-10 Finland
Mixed specific developmental disorders
3.6
11.5
51
144
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.6
11.5
285
1818
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
1.9
11.5
181
1005
DM1AI
NOMESCO Finland
Cone beam CT of paranasal sinus
3.0
11.5
66
224
NJ3DA
NOMESCO Finland
Long bones of extremities X-ray examination
8.6
11.5
24
28
JN3AD
NOMESCO Finland
Abdominal CT examination
2.0
11.5
149
772
2533A
ICD-9 Finland
Disorders of the pituitary gland and its hypothalamic control, Pituitary dwarfism[NANISMUS HYPOPHYSARIUS]
+∞
11.5
11
*
D35.3
ICD-10 Finland
Benign neoplasm: Craniopharyngeal duct
+∞
11.5
11
*
2535A
ICD-9 Finland
Disorders of the pituitary gland and its hypothalamic control, Diabetes insipidus
+∞
11.5
11
*
R01AD12
ATC
fluticasone furoate; nasal
1.4
11.5
613
4652
F32.1
ICD-10 Finland
Moderate depressive episode
2.2
11.4
120
569
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
2.3
11.4
107
480
SPAT1325
SPAT
Vaccination
1.4
11.4
656
5045
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.8
11.4
198
1140
J45.0
ICD-10 Finland
Predominantly allergic asthma
1.8
11.4
194
1107
WX780
NOMESCO Finland
Remote monitoring CPAP
2.3
11.3
104
464
F41.2
ICD-10 Finland
Mixed anxiety and depressive disorder
1.9
11.3
179
995
F60.31
ICD-10 Finland
Emotionally unstable personality disorder, borderline condition
4.5
11.3
39
88
A07AA02
ATC
nystatin; oral
2.3
11.3
106
478
M54.2
ICD-10 Finland
Cervicalgia
2.0
11.2
141
721
DMB20
NOMESCO Finland
Functional endoscopic opening of maxillary antrum
2.2
11.2
114
534
N48.4
ICD-10 Finland
Impotence of organic origin
3.0
11.2
65
224
F31.4
ICD-10 Finland
Bipolar affective disorder, current episode severe depression without psychotic symptoms
3.5
11.2
50
143
A08.4
ICD-10 Finland
Viral intestinal infection, unspecified
2.2
11.1
110
506
R56.8
ICD-10 Finland
Other and unspecified convulsions
2.0
11.1
142
729
9530/0-C70.0
ICD-O-3
Meningioma, NOS, of cerebral meninges
7.1
11.0
26
37
R03AK06
ATC
salmeterol and fluticasone; inhalant
1.7
11.0
258
1624
F31.6
ICD-10 Finland
Bipolar affective disorder, current episode mixed
4.0
11.0
42
105
R35
ICD-10 Finland
Polyuria
2.1
11.0
122
595
NA7DG
NOMESCO Finland
Spine and spinal cord very extensive MRI examination with high intensity magnet
4.8
11.0
35
73
318
Kela drug reimbursment
Teriparatide
43.5
10.9
13
*
D35.1
ICD-10 Finland
Benign neoplasm: Parathyroid gland
43.5
10.9
13
*
F33.4
ICD-10 Finland
Recurrent depressive disorder, currently in remission
3.0
10.9
62
210
R13
ICD-10 Finland
Dysphagia
2.1
10.8
116
556
N06AX18
ATC
reboxetine; oral
4.8
10.8
35
74
NA1AA
NOMESCO Finland
Cervical spine X-ray examination without contrast
2.6
10.8
79
311
WZC10
NOMESCO Finland
Extensive specialist consultion with written report
2.2
10.8
106
489
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
2.0
10.8
144
755
YX8VG
NOMESCO Finland
Stereotactic MRI exmaination with high intensity magnet for dose design of radiotherapy
10.6
10.8
20
19
M81.8
ICD-10 Finland
Other osteoporosis
8.9
10.7
22
25
T73
ICPC
Neoplasm endocrine other/unspecified
28.1
10.7
14
5
C10AA07
ATC
rosuvastatin; oral
1.5
10.7
408
2889
J01FA09
ATC
clarithromycin; systemic
1.4
10.7
628
4837
SPAT1215
SPAT
Assessment of need for medical rehabilitation
2.3
10.7
95
419
BA1AE
NOMESCO Finland
Thyroiid ultrasound examination
4.3
10.7
38
89
H53.2
ICD-10 Finland
Diplopia
2.7
10.6
71
267
N06AA10
ATC
nortriptyline; systemic
3.4
10.6
50
149
E89.4
ICD-10 Finland
Postprocedural ovarian failure
60.2
10.6
12
*
N04BC01
ATC
bromocriptine; oral
60.2
10.6
12
*
AAK40
NOMESCO Finland
Closure of cerebrospinal fluid fistula
60.2
10.6
12
*
XKD00
NOMESCO Finland
Uroflowmetry
1.6
10.6
289
1894
C10AA01
ATC
simvastatin; oral
1.4
10.6
654
5080
N17.9
ICD-10 Finland
Acute renal failure, unspecified
2.7
10.5
71
270
SAA02
NOMESCO Finland
Basic examination of mouth
1.3
10.5
1485
13122
M01AX17
ATC
nimesulide; oral
1.5
10.5
386
2714
R62.0
ICD-10 Finland
Delayed milestone
3.2
10.4
54
173
A12BA01
ATC
potassium chloride; oral
2.9
10.4
62
218
A02BC04
ATC
rabeprazole; oral
1.9
10.4
157
860
E30.00
ICD-10 Finland
Familial delayed puberty
110.4
10.4
11
*
25311
ICD-8 Finland
Diseases of pituitary gland, Hypopituitarismus partialis
+∞
10.4
10
*
25300
ICD-8 Finland
Diseases of pituitary gland, Aeromegalia
+∞
10.4
10
*
25319
ICD-8 Finland
Diseases of pituitary gland, Hypopituitarismus alia sive NUD
+∞
10.4
10
*
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
1.8
10.4
172
974
NF1AA
NOMESCO Finland
Hip X-ray examination
2.0
10.4
137
715
C07AB02
ATC
metoprolol; systemic
1.6
10.4
297
1966
R01AD58
ATC
fluticasone, combinations; inhalant, nasal
1.5
10.3
425
3056
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.5
10.3
418
2994
F82
ICD-10 Finland
Specific developmental disorder of motor function
4.1
10.3
39
97
E78.01
ICD-10 Finland
Pure hypercholesterolaemia
1.6
10.2
313
2108
M03BC51
ATC
orphenadrine, combinations; systemic
1.4
10.2
525
3943
R01AD01
ATC
beclometasone; nasal
1.6
10.2
288
1903
S50
ICPC
Skin, Medication/prescr/renewal
6.6
10.2
25
38
N30.0
ICD-10 Finland
Acute cystitis
1.7
10.1
196
1167
J01FA06
ATC
roxithromycin; oral
1.4
10.1
728
5795
R03BA01
ATC
beclometasone; inhalant
1.6
10.1
246
1562
A02BA02
ATC
ranitidine; systemic
1.6
10.1
310
2089
N03AF02
ATC
oxcarbazepine; oral
2.4
10.1
87
376
R1230
NOMESCO Finland
Neuropsychological evaluation of need and possibilities to rehabilitation
3.2
10.1
52
167
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.5
10.0
420
3029
M79.1
ICD-10 Finland
Myalgia
1.7
10.0
231
1446
H02AB07
ATC
prednisone; oral
1.6
10.0
237
1495
M80.4
ICD-10 Finland
Drug-induced osteoporosis with pathological fracture
14.6
10.0
16
11
SBB00
NOMESCO Finland
Fotograf of mouth and teeth
2.1
10.0
108
522
H52.0
ICD-10 Finland
Hypermetropia
3.0
10.0
55
185
J01DA01
ATC
[U] cefalexin; systemic
1.3
9.9
1231
10633
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
3.1
9.9
53
175
J45
ICD-10 Finland
Asthma
1.8
9.9
176
1022
BC00A
NOMESCO Finland
NA
12.2
9.8
17
14
J46
ICD-10 Finland
Status asthmaticus
3.1
9.8
52
170
TAB20
NOMESCO Finland
Epidural puncture
8.1
9.8
21
26
F60.5
ICD-10 Finland
Anankastic personality disorder
4.4
9.8
34
78
N05AX12
ATC
aripiprazole; systemic
2.2
9.8
97
451
F31.8
ICD-10 Finland
Other bipolar affective disorders
3.1
9.8
51
165
F41.3
ICD-10 Finland
Other mixed anxiety disorders
3.8
9.8
40
107
WF099
NOMESCO Finland
Other radiotherapy
9.6
9.7
19
20
KFH00
NOMESCO Finland
Operation for undescended or ectopic testis
6.5
9.7
24
37
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
2.1
9.7
110
541
S97
ICPC
Chronic ulcer skin
2.2
9.7
93
425
M03BX01
ATC
baclofen; systemic
3.6
9.7
42
118
B01AB05
ATC
enoxaparin; parenteral
1.4
9.7
484
3610
R03AC03
ATC
terbutaline; inhalant
1.6
9.7
263
1719
AEA00
NOMESCO Finland
Replacement of impulse generator of stimulation device in the nervous system
7.4
9.7
22
30
G72.8
ICD-10 Finland
Other specified myopathies
3.8
9.7
39
103
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.4
9.7
427
3110
K59.09
ICD-10 Finland
Constipation, unspecified
2.1
9.6
112
557
BBA40
NOMESCO Finland
Subtotal parathyroidectomy
55.2
9.6
11
*
R05DA20
ATC
opium alkaloids and derivatives - combinations
1.4
9.6
468
3471
Z01.9
ICD-10 Finland
Special examination, unspecified
2.1
9.6
109
536
M01AC06
ATC
meloxicam; systemic, rectal
1.4
9.6
619
4834
O99.2
ICD-10 Finland
Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium
4.5
9.6
32
71
Q53.2
ICD-10 Finland
Undescended testicle, bilateral
11.4
9.5
17
15
M80.9
ICD-10 Finland
Unspecified osteoporosis with pathological fracture
5.0
9.5
29
58
F90.0
ICD-10 Finland
Disturbance of activity and attention
2.2
9.5
94
435
R52.1
ICD-10 Finland
Chronic intractable pain
6.0
9.5
25
42
SPAT1243
SPAT
Psychiatric/psychological examination
2.4
9.5
80
342
F43.22
ICD-10 Finland
Adaptation disorder with mixed anxiety and depression
2.3
9.5
86
383
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
1.6
9.5
222
1396
E78.29
ICD-10 Finland
Other mixed hyperlipidaemia
4.8
9.4
30
63
G04CA01
ATC
alfuzosin; oral
1.6
9.4
225
1420
E27.0
ICD-10 Finland
Other adrenocortical overactivity
100.3
9.4
10
*
Z71.8
ICD-10 Finland
Other specified counselling
1.4
9.4
469
3497
V04CD01
ATC
metyrapone; oral
+∞
9.4
9
*
E24.8
ICD-10 Finland
Other Cushing syndrome
+∞
9.4
9
*
E22.2
ICD-10 Finland
Syndrome of inappropriate secretion of antidiuretic hormone
+∞
9.4
9
*
BF10A
NOMESCO Finland
NA
+∞
9.4
9
*
AAF05
NOMESCO Finland
Ventriculoperitoneal shunt
4.6
9.4
31
68
R1250
NOMESCO Finland
Evaluation of functional capability
2.8
9.4
57
205
A28
ICPC
Limited function/disability NOS
1.7
9.4
213
1327
G43.0
ICD-10 Finland
Migraine without aura [common migraine]
2.0
9.4
112
564
L01
ICPC
Neck symptom/complaint
1.6
9.3
241
1554
G03FB06
ATC
medroxyprogesterone and estrogen; systemic (progestogens and estrogens, sequential prep.)
2.2
9.3
95
445
SPAT1252
SPAT
Overall medication plan or its review
2.0
9.3
114
581
F11.22
ICD-10 Finland
Addiction-induced dependence is currently independent but uses substitute intermittent medication
4.9
9.3
29
60
SFC01
NOMESCO Finland
Adjuvant procedure of filling therapy
1.4
9.3
521
3969
F41.1
ICD-10 Finland
Generalized anxiety disorder
2.1
9.2
97
461
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
1.9
9.2
126
669
R06AX22
ATC
ebastine; oral
1.5
9.2
313
2158
R03AK07
ATC
formoterol and budesonide; inhalant
1.5
9.2
361
2565
XX3DW
NOMESCO Finland
Time consuming IT work
1.7
9.2
177
1053
N05AH03
ATC
olanzapine; systemic
1.9
9.2
133
718
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
1.4
9.2
527
4027
SHA02
NOMESCO Finland
Correction of physiology of bite - basic therapy visit
1.9
9.1
127
678
N05AN01
ATC
lithium; oral
2.7
9.1
62
237
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
3.0
9.1
49
163
M01AC01
ATC
piroxicam; systemic, rectal
1.6
9.1
223
1419
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
1.8
9.1
164
957
NA1AD
NOMESCO Finland
Cervical spine CT examination
2.2
9.1
89
412
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
1.8
9.1
149
842
WX882
NOMESCO Finland
High dependency care
2.1
9.0
103
509
R06.2
ICD-10 Finland
Wheezing
2.1
9.0
103
510
J01MA14
ATC
moxifloxacin; systemic
1.8
9.0
156
900
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
2.3
9.0
83
374
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.3
9.0
1146
9882
WZA90
NOMESCO Finland
Other doctors statement
1.4
9.0
493
3736
G04BD04
ATC
oxybutynin; oral, transdermal
2.3
9.0
80
354
SPAT1255
SPAT
Intravenous administration of medicine
2.0
9.0
117
608
E83.50
ICD-10 Finland
Hypercalcemia
6.5
8.9
22
34
P01AB01
ATC
metronidazole; oral, rectal
1.3
8.9
676
5411
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
2.6
8.9
61
236
E000001
ATC
NA
1.4
8.9
397
2898
A01
ICPC
Pain general/multiple sites
1.9
8.8
130
708
E16.2
ICD-10 Finland
Hypoglycaemia, unspecified
3.7
8.8
36
97
JKA21
NOMESCO Finland
Laparoscopic cholecystectomy
1.7
8.8
175
1051
P20
ICPC
Memory disturbance
1.8
8.8
138
770
D07AB02
ATC
hydrocortisone butyrate; topical
1.4
8.8
503
3837
L08
ICPC
Shoulder symptom/complaint
1.5
8.8
322
2255
SAA01
NOMESCO Finland
Simple examination of mouth
1.3
8.8
1583
14279
WX1PA
NOMESCO Finland
Total body mineral density measurement with Dual energy X-ray absorptiometry (DXA)
9.5
8.8
17
18
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
2.1
8.7
98
479
N62
ICD-10 Finland
Hypertrophy of breast
2.4
8.7
70
294
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
1.9
8.7
120
639
N29
ICPC
Neurological sympt/complt other
3.2
8.7
43
135
E21.3
ICD-10 Finland
Hyperparathyroidism, unspecified
50.1
8.7
10
*
2159
FHL
Other measure in this category
50.1
8.7
10
*
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
2.3
8.7
76
335
SPAT1033
SPAT
Irrigation or wax removal of outer auditory canal
1.5
8.6
299
2069
A01AB09
ATC
miconazole; local oral
1.8
8.6
138
774
RS221
NOMESCO Finland
NA
2.9
8.6
50
174
AA400
NOMESCO Finland
Electroconvulsive therapy
4.3
8.6
30
70
XG466
NOMESCO Finland
Sleep oxymetry
2.4
8.6
69
290
L04AD01
ATC
ciclosporin; systemic
2.7
8.6
55
204
Z01.2
ICD-10 Finland
Dental examination
1.3
8.5
900
7543
2152
FHL
Extraction, big brain
16.3
8.5
13
8
E87.6
ICD-10 Finland
Hypokalaemia
2.7
8.5
55
205
G03CA03
ATC
estradiol; nasal, systemic, rectal, transdermal, vaginal
1.4
8.5
443
3324
R03AK08
ATC
formoterol and beclometasone; inhalant
2.3
8.5
75
331
M01AH02
ATC
rofecoxib; oral
1.6
8.5
208
1322
P01
ICPC
Feeling anxious/nervous/tense
1.6
8.5
205
1300
N07BC02
ATC
methadone; systemic
10.0
8.5
16
16
SHB00
NOMESCO Finland
Prepation and fitting of bite rail to mouth
1.7
8.5
182
1115
SPAT1097
SPAT
Recording of ECG
1.6
8.5
234
1537
E29.8
ICD-10 Finland
Other testicular dysfunction
27.6
8.5
11
*
D35.9
ICD-10 Finland
Benign neoplasm: Endocrine gland, unspecified
27.6
8.5
11
*
R89.1
ICD-10 Finland
Abnormal findings in specimens from other organs, systems and tissues, abnormal level of hormones
27.6
8.5
11
*
C02AC05
ATC
moxonidine; oral
2.3
8.5
75
333
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
1.8
8.4
144
825
NAG40
NOMESCO Finland
Anterior fusion of cervical spine without fixation
2.6
8.4
61
242
H05BX01
ATC
cinacalcet; oral
90.3
8.4
9
*
R07.3
ICD-10 Finland
Other chest pain
1.7
8.4
161
957
127
Kela drug reimbursment
Transplant complication
2.9
8.4
49
172
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
1.9
8.4
113
598
TAA40
NOMESCO Finland
Cathetrisation of cerebrospinal fluid through skin
12.8
8.4
14
11
N18.8
ICD-10 Finland
Other chronic renal failure
2.8
8.3
53
195
Y29
ICPC
Genital symptom/complaint male other
4.1
8.3
31
77
UJD02
NOMESCO Finland
Gastroscopy
2.2
8.3
82
382
AA1AA
NOMESCO Finland
Head X-ray examination
4.5
8.3
28
63
E2300, D352
ICD-10 Finland
NA
+∞
8.3
8
*
25398
ICD-8 Finland
Diseases of pituitary gland, Alii definiti
+∞
8.3
8
*
E89.3
ICD-10 Finland
Postprocedural hypopituitarism
+∞
8.3
8
*
Q87.19
ICD-10 Finland
Congenital malformation syndromes predominantly associated with short stature
+∞
8.3
8
*
SPAT1296
SPAT
Other function in accordance with occupational therapy nomenclature
3.6
8.3
36
102
T88.7
ICD-10 Finland
Unspecified adverse effect of drug or medicament
3.6
8.3
35
97
K76.0
ICD-10 Finland
Fatty (change of) liver, not elsewhere classified
2.6
8.3
58
228
R25.1
ICD-10 Finland
Tremor, unspecified
2.6
8.3
57
221
J01EA01
ATC
trimethoprim; systemic
1.5
8.2
337
2413
H90.4
ICD-10 Finland
Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
2.3
8.2
75
335
205
Kela drug reimbursment
Chronic hypertension
1.4
8.2
403
2991
A12AA04
ATC
calcium carbonate; oral
3.7
8.2
34
93
7890A
ICD-9 Finland
Other symptoms involving abdomen and pelvis, Abdominal pain
2.1
8.2
90
439
SBB10
NOMESCO Finland
Teeth copy
1.7
8.2
184
1145
M01AH05
ATC
etoricoxib; oral
1.3
8.2
1143
9931
J05AB11
ATC
valaciclovir; oral
1.6
8.1
221
1445
F51.0
ICD-10 Finland
Nonorganic insomnia
1.6
8.1
234
1553
T86
ICPC
Hypothyroidism/myxoedema
2.5
8.1
59
235
R51
ICD-10 Finland
Headache
2.0
8.1
102
525
G96.0
ICD-10 Finland
Cerebrospinal fluid leak
17.2
8.1
12
7
XW000
NOMESCO Finland
Bone marrow biopsy
2.2
8.0
80
375
N97.0
ICD-10 Finland
Female infertility associated with anovulation
3.7
8.0
33
90
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
1.9
8.0
118
644
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
1.8
8.0
124
690
F50.0
ICD-10 Finland
Anorexia nervosa
5.0
8.0
24
48
D43.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Brain, supratentorial
5.0
8.0
24
48
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.3
8.0
1001
8563
N76
ICPC
Neoplasm nervous system unspecified
22.1
8.0
11
5
A01AB04
ATC
amphotericin B; local oral
2.3
8.0
69
303
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.5
8.0
243
1633
-55
ICPC
Local injection/infiltration
5.9
8.0
21
36
E86
ICD-10 Finland
Volume depletion
2.9
8.0
46
160
285
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
2.0
7.9
97
494
L02BG03
ATC
anastrozole; oral
4.0
7.9
30
76
R1220
NOMESCO Finland
Psychological examination of need and possibilities to rehabilitation
3.0
7.9
43
145
F50.9
ICD-10 Finland
Eating disorder, unspecified
4.4
7.9
27
62
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
1.7
7.9
163
991
AA1CD
NOMESCO Finland
Very extensive CT of head and brain
3.3
7.9
38
118
R05FA02
ATC
opium derivatives and expectorants; systemic
1.3
7.9
693
5649
R03BA02
ATC
budesonide; inhalant
1.4
7.8
332
2393
XF602
NOMESCO Finland
Bloodpressure monitoring
3.6
7.8
33
92
ABD32
NOMESCO Finland
Implantation of temporary spinal stimulation device
6.1
7.8
20
33
AAG50
NOMESCO Finland
Stereotactic intracranial radiotherapy
5.7
7.8
21
37
SPAT1053
SPAT
Memory test
1.7
7.8
172
1066
M02AA10
ATC
ketoprofen; topical
1.5
7.8
254
1736
R03BB04
ATC
tiotropium bromide; inhalant
1.7
7.8
145
855
K80.2
ICD-10 Finland
Calculus of gallbladder without cholecystitis
1.7
7.8
172
1067
D07AC01
ATC
betamethasone; topical
1.3
7.8
602
4817
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
2.0
7.7
89
444
Q87.14
ICD-10 Finland
Noonan's syndrome
45.1
7.7
9
*
H47.4
ICD-10 Finland
Disorders of optic chiasm
45.1
7.7
9
*
ZX050
NOMESCO Finland
Stereotactic radiotherapy
5.0
7.7
23
46
R03AC12
ATC
salmeterol; inhalant
2.3
7.7
69
308
N05AD01
ATC
haloperidol; systemic
2.5
7.7
57
231
SPAT1360
SPAT
Extensive global examination
1.8
7.7
130
745
N04BC05
ATC
pramipexole; oral
1.9
7.6
111
604
M03BA52
ATC
carisoprodol, combinations excl. psycholeptics; oral
2.6
7.6
53
207
XG410
NOMESCO Finland
Flow-volume spirometry
2.0
7.6
88
439
N75
ICPC
Benign neoplasm nervous system
18.4
7.6
11
6
F41.00
ICD-10 Finland
Moderate panic disorder
2.9
7.6
42
144
C10AX09
ATC
ezetimibe; oral
1.6
7.6
176
1105
A03FA02
ATC
cisapride; oral, rectal
1.8
7.6
116
643
H25.8
ICD-10 Finland
Other senile cataract
1.8
7.5
123
694
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
1.8
7.5
125
711
R22.9
ICD-10 Finland
Localized swelling, mass and lump, unspecified
1.8
7.5
125
712
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
2.7
7.5
48
178
EBA10
NOMESCO Finland
Surgical removal of tooth
1.5
7.5
262
1817
E78.9
ICD-10 Finland
Disorder of lipoprotein metabolism, unspecified
2.4
7.5
62
266
E000002
ATC
NA
1.6
7.5
214
1417
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
2.1
7.5
76
361
R60.9
ICD-10 Finland
Oedema, unspecified
2.1
7.5
82
400
346
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
2.0
7.4
87
437
H05BA01
ATC
calcitonin (salmon synthetic); nasal, parenteral
3.6
7.4
31
86
F31
ICD-10 Finland
Bipolar affective disorder
3.3
7.4
35
107
G40.9
ICD-10 Finland
Epilepsy, unspecified
2.1
7.4
77
366
R03AK10
ATC
vilanterol and fluticasone furoate; inhalant
2.1
7.4
80
389
2250A
ICD-9 Finland
Benign neoplasm of brain and other parts of nervous system, Brain
80.3
7.4
8
*
E30.9
ICD-10 Finland
Disorder of puberty, unspecified
80.3
7.4
8
*
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
1.7
7.4
155
947
S06.0
ICD-10 Finland
Concussion
1.5
7.4
216
1440
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
1.9
7.4
107
582
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
1.4
7.4
326
2369
TPX10
NOMESCO Finland
Implantation of vascular injection port
2.4
7.4
58
242
D43.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Central nervous system, unspecified
7.7
7.4
16
21
K02.1
ICD-10 Finland
Caries of dentine
1.3
7.4
1259
11154
R1100
NOMESCO Finland
General evaluation of the need for rehabilitation
2.6
7.4
49
188
F32.3
ICD-10 Finland
Severe depressive episode with psychotic symptoms
2.6
7.4
49
188
G43.9
ICD-10 Finland
Migraine, unspecified
1.9
7.4
107
583
TAW99
NOMESCO Finland
Other minor neurosurgical procedure
5.3
7.4
21
40
R90.8
ICD-10 Finland
Other abnormal findings on diagnostic imaging of central nervous system
3.9
7.3
28
72
G56.0
ICD-10 Finland
Carpal tunnel syndrome
1.5
7.3
215
1431
G62.9
ICD-10 Finland
Polyneuropathy, unspecified
2.3
7.3
62
271
L04AA06
ATC
mycophenolic acid; systemic
2.8
7.3
44
159
R52.9
ICD-10 Finland
Pain, unspecified
1.7
7.3
146
881
25312
ICD-8 Finland
Diseases of pituitary gland, Nanismus hypophysarius
+∞
7.3
7
*
AA4AD
NOMESCO Finland
CT of sella turcica
+∞
7.3
7
*
9350/1-C75.1
ICD-O-3
Craniopharyngioma, NOS, of pituitary gland
+∞
7.3
7
*
Q87.15
ICD-10 Finland
Prader-Willi syndrome
+∞
7.3
7
*
7597A
ICD-9 Finland
Other and unspecified congenital anomalies, Multiple congenital anomalies, so described
+∞
7.3
7
*
Q96.3
ICD-10 Finland
Mosaicism, 45,X/46,XX or XY
+∞
7.3
7
*
R05
ICD-10 Finland
Cough
1.4
7.3
346
2551
K59.0
ICD-10 Finland
Constipation
2.0
7.3
86
435
N91.0
ICD-10 Finland
Primary amenorrhoea
9.4
7.3
14
15
R06AE09
ATC
levocetirizine; oral
1.5
7.2
277
1958
G40.20
ICD-10 Finland
Complex partial seizures with only alteration of consciousness
3.9
7.2
28
73
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
1.5
7.2
226
1530
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
1.5
7.2
227
1535
NE1AA
NOMESCO Finland
Pelvis X-ray examination
1.9
7.2
98
522
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
2.4
7.2
60
258
SFA20
NOMESCO Finland
Filling on two surfaces of tooth
1.3
7.2
1214
10725
XCD10
NOMESCO Finland
Electrophysiological examination of eye
2.7
7.2
46
170
A10BH01
ATC
sitagliptin; oral
1.7
7.2
150
916
TPH07
NOMESCO Finland
Cathetrisation of artery
1.6
7.2
182
1171
J34.2
ICD-10 Finland
Deviated nasal septum
1.8
7.2
122
699
SPAT1149
SPAT
Suture or treatment of traumatic wound
1.5
7.2
221
1490
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
1.9
7.2
93
486
TNX33
NOMESCO Finland
Custom moulded cast, unspecified region
1.9
7.2
99
529
R41.0
ICD-10 Finland
Disorientation, unspecified
2.7
7.2
47
179
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
2.5
7.2
54
222
N06AX17
ATC
milnacipran; oral
3.8
7.1
28
74
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
2.9
7.1
41
142
F60.30
ICD-10 Finland
Emotionally unstable personality disorder, impulsive
2.9
7.1
41
142
XF404
NOMESCO Finland
Ambulatory ECG
1.7
7.1
159
987
WX290
NOMESCO Finland
Other blockade of nerve
1.3
7.1
960
8248
D33.00
ICD-10 Finland
Medial pilosytic astrocytoma of the cerebrum
20.1
7.1
10
5
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
2.4
7.1
57
242
SPAT1281
SPAT
Other administrative function
1.7
7.1
157
972
M80
ICD-10 Finland
Osteoporosis with pathological fracture
6.6
7.1
17
26
D32.9
ICD-10 Finland
Benign neoplasm: Meninges, unspecified
6.6
7.1
17
26
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
2.4
7.1
59
253
A10AE04
ATC
insulin glargine; parenteral
1.6
7.1
173
1104
F11.24
ICD-10 Finland
Addiction-induced dependence caused by opiates active addiction
6.0
7.1
18
30
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.4
7.0
301
2174
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.3
7.0
814
6867
J45.8
ICD-10 Finland
Mixed asthma
2.3
7.0
62
277
EBA05
NOMESCO Finland
Complicated extraction of tooth
1.4
7.0
371
2789
SPAT1226
SPAT
Implementation of occupational therapy rehabilitation plan
2.5
7.0
50
201
R41.3
ICD-10 Finland
Other amnesia
2.7
6.9
43
159
C03EB01
ATC
furosemide and potassium-sparing agents; systemic
2.4
6.9
53
220
JL5BG
NOMESCO Finland
MRI examinaiton of bile and pancreas ducts with high intesity magnet
2.7
6.9
45
170
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.4
6.9
318
2329
NA1EA
NOMESCO Finland
Cervical spine X-ray examination with flexion
3.2
6.9
33
103
F61.0
ICD-10 Finland
Mixed personality disorders
2.7
6.9
44
163
M79.7
ICD-10 Finland
Fibromyalgia
2.5
6.9
50
203
I95.1
ICD-10 Finland
Orthostatic hypotension
2.5
6.9
50
203
C03AA03
ATC
hydrochlorothiazide; oral
1.7
6.9
128
756
J31.0
ICD-10 Finland
Chronic rhinitis
1.7
6.8
145
890
H26.2
ICD-10 Finland
Complicated cataract
3.4
6.8
31
93
P80
ICPC
Personality disorder
8.3
6.8
14
17
H47.0
ICD-10 Finland
Disorders of optic nerve, not elsewhere classified
8.3
6.8
14
17
Z01.4
ICD-10 Finland
Gynaecological examination (general)(routine)
1.5
6.8
205
1375
Z63.7
ICD-10 Finland
Other stressful life events affecting family and household
2.4
6.8
55
235
ABD99
NOMESCO Finland
Other operation on spinal cord or nerve for pain or impaired function
10.9
6.8
12
11
R03DA04
ATC
theophylline; systemic, rectal
2.1
6.8
70
332
F80.8
ICD-10 Finland
Other developmental disorders of speech and language
5.0
6.8
20
40
H47.1
ICD-10 Finland
Papilloedema, unspecified
5.0
6.8
20
40
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
1.7
6.8
129
767
M81.4
ICD-10 Finland
Drug-induced osteoporosis
9.3
6.8
13
14
9109
FHL
Other measure in this category
9.3
6.8
13
14
R94.6
ICD-10 Finland
Abnormal results of thyroid function studies
6.1
6.8
17
28
J01DC02
ATC
cefuroxime; systemic
1.8
6.8
109
614
K00.29
ICD-10 Finland
Other or indefinite deviation in the shape or size of the teeth
40.1
6.8
8
*
AAF99
NOMESCO Finland
Other shunt operation on ventricle of brain or intracerebral cyst
16.7
6.7
10
6
J09
ICD-10 Finland
Influenza due to identified zoonotic or pandemic influenza virus
2.5
6.7
49
199
NA7EA
NOMESCO Finland
Scoliosis X-ray examination
3.2
6.7
33
105
L01BA01
ATC
methotrexate; systemic (folic acid analog.)
2.2
6.7
65
302
WX402
NOMESCO Finland
General anaesthesia
1.4
6.7
338
2518
TDM10
NOMESCO Finland
Puncture of maxillary antrum
2.1
6.7
72
349
P03
ICPC
Feeling depressed
1.6
6.7
172
1109
XF600
NOMESCO Finland
Bloodpressure measurement
1.7
6.7
143
879
C74.1
ICD-10 Finland
Malignant neoplasm: Medulla of adrenal gland
22.6
6.7
9
*
D33.2
ICD-10 Finland
Benign neoplasm: Brain, unspecified
22.6
6.7
9
*
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
2.1
6.7
70
338
K59.1
ICD-10 Finland
Functional diarrhoea
1.9
6.7
87
456
SPAT1307
SPAT
Psychosocial counselling and guidance
1.7
6.7
130
781
M47.82
ICD-10 Finland
Other spondylosis, cervical region
2.2
6.6
65
305
EBA15
NOMESCO Finland
Extraction of large number of teeth
2.0
6.6
83
430
M01AB05
ATC
diclofenac; systemic, rectal
1.2
6.6
1311
11753
SPAT1074
SPAT
Venesection
6.4
6.6
16
25
F41.01
ICD-10 Finland
Severe panic disorder
5.2
6.6
19
37
XG474
NOMESCO Finland
Exhalation nntrogen oxide
2.2
6.6
64
298
H26.3
ICD-10 Finland
Drug-induced cataract
4.6
6.6
21
46
Q53.1
ICD-10 Finland
Undescended testicle, unilateral
4.6
6.6
21
46
Z75.1
ICD-10 Finland
Person awaiting admission to adequate facility elsewhere
3.5
6.6
28
80
ZXA05
NOMESCO Finland
Left side
1.4
6.6
407
3138
E66.2
ICD-10 Finland
Extreme obesity with alveolar hypoventilation
4.0
6.6
24
60
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
2.0
6.6
80
409
N03AB02
ATC
phenytoin; systemic
3.9
6.6
25
65
WZC05
NOMESCO Finland
Specialty-specific consultation based on referral by dentist or doctor
1.7
6.5
115
670
N03AX14
ATC
levetiracetam; systemic
2.1
6.5
66
312
BCA31
NOMESCO Finland
Endoscopic unilateral adrenalectomy
10.0
6.5
12
12
D89.89
ICD-10 Finland
Other specified disorders involving the immune mechanism, not elsewhere classified
10.0
6.5
12
12
F60.8
ICD-10 Finland
Other specific personality disorders
4.3
6.5
22
51
OAB72
NOMESCO Finland
Weight control and weight loss guidance
4.8
6.5
20
42
R02
ICPC
Shortness of breath/dyspnoea
1.5
6.5
194
1298
JN3BD
NOMESCO Finland
Extensive abdominal CT
1.6
6.5
176
1152
SPAT1137
SPAT
Taking care of patient’s/customer’s hygiene
2.2
6.5
63
293
L14
ICPC
Leg/thigh symptom/complaint
1.7
6.5
119
700
A12AA06
ATC
calcium lactate gluconate; oral
70.0
6.4
7
*
E28.8
ICD-10 Finland
Other ovarian dysfunction
70.0
6.4
7
*
D35.50
ICD-10 Finland
Carotid body
70.0
6.4
7
*
Z46.8
ICD-10 Finland
Fitting and adjustment of other specified devices
2.5
6.4
46
185
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
2.4
6.4
50
211
M80.5
ICD-10 Finland
Idiopathic osteoporosis with pathological fracture
7.4
6.4
14
19
K04.5
ICD-10 Finland
Chronic apical periodontitis
1.3
6.4
452
3555
G47.9
ICD-10 Finland
Sleep disorder, unspecified
2.4
6.4
49
204
R06AX27
ATC
desloratadine; oral
1.3
6.4
560
4545
SPAT1221
SPAT
Guidance concerning rehabilitation services and livelihood
2.6
6.4
43
168
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
2.6
6.4
45
178
EB1JA
NOMESCO Finland
Double panorama tomography of teeth and jaws or similar X-ray examination
3.8
6.4
25
67
SHA01
NOMESCO Finland
Correction of physiology of bite - simple therapy visit
1.6
6.4
179
1182
B02.9
ICD-10 Finland
Zoster without complication
1.9
6.3
83
438
SFA00
NOMESCO Finland
Small filling
1.5
6.3
235
1648
F40.1
ICD-10 Finland
Social phobias
2.3
6.3
57
256
A29
ICPC
General symptom/complaint other
1.5
6.3
179
1186
N07CA01
ATC
betahistine; oral
1.8
6.3
106
609
SJA03
NOMESCO Finland
Demanding plan for orthodontic care
8.2
6.3
13
16
D80.1
ICD-10 Finland
Nonfamilial hypogammaglobulinaemia
8.2
6.3
13
16
T10
ICPC
Growth delay
8.2
6.3
13
16
S10
ICPC
Boil/carbuncle
1.8
6.3
102
578
K80.0
ICD-10 Finland
Calculus of gallbladder with acute cholecystitis
2.1
6.3
65
312
TPH00
NOMESCO Finland
Phlebotomy
5.2
6.3
18
35
Z03.8
ICD-10 Finland
Observation for other suspected diseases and conditions
2.0
6.3
72
361
LC2AE
NOMESCO Finland
Ultrasound examination of uterus and parametria
1.7
6.3
126
760
L29
ICPC
Musculoskeletal sympt/complt other
1.7
6.3
121
723
NA3EA
NOMESCO Finland
Lumbar spine X-ray examination with flexion
2.2
6.3
57
258
ACC51
NOMESCO Finland
Release of median nerve
1.7
6.3
116
686
9101
FHL
Bone biopsy
9.3
6.3
12
13
A10BK03
ATC
empagliflozin; oral
1.7
6.3
123
741
JN4BD
NOMESCO Finland
Extensive body CT
1.6
6.3
172
1128
BBA20
NOMESCO Finland
Exploration of parathyroid gland
+∞
6.2
6
*
E27.8
ICD-10 Finland
Other specified disorders of adrenal gland
+∞
6.2
6
*
D352, E221
ICD-10 Finland
NA
+∞
6.2
6
*
E26.9
ICD-10 Finland
Hyperaldosteronism, unspecified
+∞
6.2
6
*
Y55
ICPC
Male Genital, Local injection/infiltration
+∞
6.2
6
*
W00
ICD-10 Finland
Fall on same level involving ice and snow
1.5
6.2
181
1206
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
1.7
6.2
122
731
K59.00
ICD-10 Finland
Constipation caused by slow bowel passage (SCT)
2.5
6.2
44
175
G50.1
ICD-10 Finland
Atypical facial pain
3.0
6.2
33
112
H25.0
ICD-10 Finland
Senile incipient cataract
2.0
6.2
73
370
M01AB55
ATC
diclofenac, combinations; oral
1.8
6.2
95
530
Z96.1
ICD-10 Finland
Presence of intraocular lens
1.6
6.2
143
900
M89.0
ICD-10 Finland
Algoneurodystrophy
3.8
6.2
24
64
KA1AE
NOMESCO Finland
Kidney ultrasound examination
2.4
6.2
47
194
C08DA01
ATC
verapamil; systemic
2.1
6.2
64
309
J02AC02
ATC
itraconazole; systemic
1.4
6.2
287
2108
R4190
NOMESCO Finland
Nutritional therapy
1.8
6.1
104
598
EB1BA
NOMESCO Finland
Extensive intraoral X-ray examination
5.7
6.1
16
28
SFA30
NOMESCO Finland
Filling on tree or more surfaces of tooth
1.3
6.1
764
6479
F31.0
ICD-10 Finland
Bipolar affective disorder, current episode hypomanic
2.9
6.1
33
113
XQ800
NOMESCO Finland
Prick test
1.6
6.1
160
1041
L68.0
ICD-10 Finland
Hirsutism
7.7
6.1
13
17
I95.9
ICD-10 Finland
Hypotension, unspecified
3.4
6.1
27
80
RS222
NOMESCO Finland
NA
2.7
6.1
37
136
A10BJ06
ATC
semaglutide; parenteral
2.1
6.1
66
324
Z50.1
ICD-10 Finland
Other physical therapy
1.9
6.1
85
460
F32.8
ICD-10 Finland
Other depressive episodes
2.8
6.1
36
130
KF8AE
NOMESCO Finland
Ultrasound examination of scrotum
2.1
6.1
63
303
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.4
6.0
340
2580
G04CA02
ATC
tamsulosin; oral
1.4
6.0
350
2667
XF402
NOMESCO Finland
ECG with work load test
1.5
6.0
177
1181
E89.00
ICD-10 Finland
Postirradiation hypothyroidism
4.9
6.0
18
37
F33.1
ICD-10 Finland
Recurrent depressive disorder, current episode moderate
2.2
6.0
55
249
H54.2
ICD-10 Finland
Moderate visual impairment, binocular
4.4
6.0
20
46
EB1AI
NOMESCO Finland
Cone beam imaging of teeth and jaws (one quarter)
2.7
6.0
39
147
Mortality – FinRegistry
↥Association
Association between endpoint E4_HYPOPIT and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| E4_HYPOPIT | 2.411 [2.07, 2.8] | < 0.001 |
| Birth year | 0.995 [0.99, 1.0] | 0.239 |
During the follow-up period (1.1.1998 — 31.12.2019), 540 out of 4131 females with E4_HYPOPIT died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| E4_HYPOPIT | 1.663 [1.44, 1.92] | < 0.001 |
| Birth year | 0.983 [0.97, 0.99] | < 0.001 |
During the follow-up period (1.1.1998 — 31.12.2019), 775 out of 6770 males with E4_HYPOPIT died.
Mortality risk
Mortality risk for people of age
years, who have E4_HYPOPIT.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.197% | 0.354% |
| 5 | 1.331% | 1.862% |
| 10 | 3.358% | 4.465% |
| 15 | 6.434% | 8.397% |
| 20 | 11.583% | 14.004% |
Relationships between endpoints
↥Index endpoint: E4_HYPOPIT – Hypopituitarism
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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