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Testicular dysfunction

E4_TESTIDYS

testicular disease: A non-neoplastic or neoplastic disorder affecting the testis. Representative examples include torsion, infarction, germ cell tumor, sex cord-stromal tumor, lymphoma, and leukemia.

Suggest a new description

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

only males

226837

2. Check conditions

None

226837

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 E29
  • Cause of death: ICD-10 E29

2 out of 7 registries used, show all original rules.

1091

4. Check minimum number of events

None

1091

5. Include endpoints

1333

6. Filter based on genotype QC (FinnGen only)

1333

Control definitions (FinnGen only)

Control exclude
E4_ENDOGLAND

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
E20-E35
Name in latin
Dysfunctio testicularis

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 1333 - 1333
Unadjusted period prevalence (%) 0.59 - 0.59
Median age at first event (years) 51.79 - 51.79

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1175
Matched controls
11750
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
121
Kela drug reimbursment
Severe hypofunction of sexual glands
389.7
323.0
391
15
E29.1
ICD-10 Finland
Testicular hypofunction
548.9
323.0
882
64
G03BA03
ATC
testosterone; systemic, rectal, sublingual, transdermal
118.6
323.0
986
493
E23.04
ICD-10 Finland
Hypogonadotropic hypogonadism
85.2
163.2
181
25
E29.9
ICD-10 Finland
Testicular dysfunction, unspecified
118.7
91.5
98
9
Y28
ICPC
Limited function/disability (Y)
42.3
86.6
108
28
A50
ICPC
General and Unspecified, Medication/prescr/renewal
14.1
83.9
148
119
A55
ICPC
General and Unspecified, Local injection/infiltration
28.2
64.9
89
34
101
Kela drug reimbursment
Anterior pituitary hypofunction
+∞
63.1
60
*
G47.3
ICD-10 Finland
Sleep apnoea
2.9
55.2
454
2101
E29.8
ICD-10 Finland
Other testicular dysfunction
125.0
45.1
48
*
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
9.4
41.9
89
102
G03GA01
ATC
chorionic gonadotrophin; parenteral
35.5
39.7
51
15
AA4CG
NOMESCO Finland
Extensive MRI examination of sella turcica with high intensity magnet
30.2
38.9
52
18
SPAT1256
SPAT
Intramuscular and subcutaneous injection
2.2
35.4
495
2877
KF8AE
NOMESCO Finland
Ultrasound examination of scrotum
5.5
34.5
107
211
N48.4
ICD-10 Finland
Impotence of organic origin
5.8
32.1
95
177
KFC00
NOMESCO Finland
Unilateral orchiectomy
14.5
31.8
54
39
G04CA01
ATC
alfuzosin; oral
2.7
30.9
247
1063
R5140
NOMESCO Finland
Monitoring the use of the aid
2.9
30.8
216
856
N03AX16
ATC
pregabalin; oral
2.5
30.5
291
1379
N02AX02
ATC
tramadol; systemic, rectal
2.1
30.5
529
3314
M01AH05
ATC
etoricoxib; oral
2.1
30.4
726
5174
H03AA01
ATC
levothyroxine sodium; systemic
3.2
30.3
176
615
N06AX11
ATC
mirtazapine; oral
2.2
29.9
385
2112
E29
ICD-10 Finland
Testicular dysfunction
102.6
27.8
30
*
A02BC05
ATC
esomeprazole; systemic
2.1
27.7
449
2702
N05BA04
ATC
oxazepam; oral
2.4
27.0
274
1329
T99
ICPC
Endocr/metab/nutrit disease other
10.2
26.2
52
53
N06AB10
ATC
escitalopram; oral
2.4
25.6
257
1236
N03AX12
ATC
gabapentin; oral
2.7
25.2
195
814
H02AB09
ATC
hydrocortisone; systemic
15.1
24.8
41
28
N06AX12
ATC
bupropion; oral
3.5
24.7
123
381
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.9
24.0
565
3859
N06AX16
ATC
venlafaxine; oral
2.6
23.6
186
783
J01MA02
ATC
ciprofloxacin; systemic
1.9
23.3
437
2737
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.6
23.1
188
804
WX408
NOMESCO Finland
General anesthesy, balanced
2.1
22.9
324
1814
A02BC02
ATC
pantoprazole; systemic
1.8
22.7
681
5017
J01DB01
ATC
cefalexin; oral
2.0
22.3
950
7910
R53
ICD-10 Finland
Malaise and fatigue
2.4
22.0
203
929
N06AX26
ATC
vortioxetine; oral
3.7
21.8
99
285
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.9
21.6
476
3140
N06AX21
ATC
duloxetine; oral
2.9
21.5
137
506
N05CF02
ATC
zolpidem; oral
2.3
21.4
218
1048
-50
ICPC
Medication/prescr/renewal
5.0
21.4
70
147
M03BX02
ATC
tizanidine; oral
1.8
21.2
740
5676
N02AJ06
ATC
codeine and paracetamol; systemic
1.9
21.2
473
3129
J01FA10
ATC
azithromycin; systemic
1.8
21.1
637
4653
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
3.2
21.1
115
382
J01CA04
ATC
amoxicillin; systemic
1.9
20.8
901
7412
A06AC01
ATC
ispaghula (psylla seeds); oral
2.3
20.8
214
1033
T28
ICPC
Limited function/disability (T)
16.1
20.6
33
21
Q98.0
ICD-10 Finland
Klinefelter syndrome karyotype 47,XXY
112.0
20.6
22
*
D40.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Testis
9.8
20.4
41
43
R03AC02
ATC
salbutamol; inhalant
1.8
19.7
544
3829
N62
ICD-10 Finland
Hypertrophy of breast
7.9
19.7
45
59
N02BE01
ATC
paracetamol; systemic, rectal
1.9
19.3
924
7740
R01AD09
ATC
mometasone; nasal
1.8
18.9
479
3266
E34.9
ICD-10 Finland
Endocrine disorder, unspecified
+∞
18.8
18
*
N05CF01
ATC
zopiclone; oral
1.9
18.8
323
1929
XKD00
NOMESCO Finland
Uroflowmetry
2.2
18.7
223
1147
N06AB04
ATC
citalopram; systemic
2.1
18.7
231
1210
N05AH04
ATC
quetiapine; oral
2.1
18.5
228
1191
D75.1
ICD-10 Finland
Secondary polycythaemia
12.1
18.4
33
28
M03BC51
ATC
orphenadrine, combinations; systemic
1.9
18.3
316
1888
M54.5
ICD-10 Finland
Low back pain
1.9
18.2
367
2312
M01AB05
ATC
diclofenac; systemic, rectal
1.8
18.2
780
6220
E23.00
ICD-10 Finland
Panhypopituitarism
+∞
17.7
17
*
J01AA02
ATC
doxycycline; systemic
1.8
17.5
831
6792
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.9
17.5
324
1977
T55
ICPC
Metabolic, Local injection/infiltration
29.3
17.5
23
8
UKC02
NOMESCO Finland
Cystoscopy
2.3
17.2
179
864
N46
ICD-10 Finland
Male infertility
4.4
16.8
62
148
M03BC01
ATC
orphenadrine (citrate); systemic
1.9
16.7
285
1684
R01AD12
ATC
fluticasone furoate; nasal
1.9
16.7
318
1956
I10
ICD-10 Finland
Essential (primary) hypertension
1.7
16.7
556
4068
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.9
16.7
310
1891
R06.0
ICD-10 Finland
Dyspnoea
2.0
16.7
230
1255
WX723
NOMESCO Finland
CPAP therapy
3.4
16.6
83
258
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.2
16.6
195
994
R01AD08
ATC
fluticasone; nasal
1.9
16.5
310
1895
T50
ICPC
Metabolic, Medication/prescr/renewal
40.7
16.4
20
5
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.7
16.3
114
443
D35.2
ICD-10 Finland
Benign neoplasm: Pituitary gland
21.3
16.0
23
11
H02AB06
ATC
prednisolone; systemic
1.7
15.8
457
3195
N40
ICD-10 Finland
Hyperplasia of prostate
1.9
15.8
271
1601
M01AC06
ATC
meloxicam; systemic, rectal
1.8
15.7
363
2372
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
3.4
15.6
78
243
R06.5
ICD-10 Finland
Mouth breathing
2.3
15.1
151
712
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
4.5
15.0
53
122
M48.0
ICD-10 Finland
Spinal stenosis
2.6
14.9
114
469
L02BA01
ATC
tamoxifen; oral
25.4
14.7
20
8
M01AE02
ATC
naproxen; oral, rectal
1.6
14.6
601
4596
C62.11
ICD-10 Finland
Malignant tumor of the descending testicle, seminoma
14.4
14.6
24
17
M54.4
ICD-10 Finland
Lumbago with sciatica
2.1
14.5
184
966
Q98.4
ICD-10 Finland
Klinefelter syndrome, unspecified
151.8
14.5
15
*
A02BC03
ATC
lansoprazole; oral
1.8
14.4
282
1736
E66.00
ICD-10 Finland
Metabolic syndrome
3.0
14.4
87
310
R06AX27
ATC
desloratadine; oral
1.8
14.3
271
1650
Y50
ICPC
Male Genital, Medication/prescr/renewal
27.5
14.3
19
7
E66.01
ICD-10 Finland
Obesity due to excess calories
2.8
14.2
92
343
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
2.1
14.2
178
930
J02AC01
ATC
fluconazole; systemic
1.9
14.2
220
1246
N06AB06
ATC
sertraline; oral
2.4
14.0
127
569
N05BA12
ATC
alprazolam; oral
2.4
14.0
120
525
C09CA06
ATC
candesartan; oral
1.9
14.0
224
1287
A02BC01
ATC
omeprazole; systemic
1.8
13.9
253
1521
WX780
NOMESCO Finland
Remote monitoring CPAP
2.9
13.9
84
299
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.6
13.8
553
4179
L02BG04
ATC
letrozole; oral
13.8
13.7
23
17
R52.2
ICD-10 Finland
Other chronic pain
4.6
13.6
47
106
P01AB01
ATC
metronidazole; oral, rectal
1.7
13.5
315
2045
R07.4
ICD-10 Finland
Chest pain, unspecified
1.8
13.5
278
1736
Z01.8
ICD-10 Finland
Other specified special examinations
1.9
13.4
228
1333
C07AA05
ATC
propranolol; systemic
2.0
13.4
187
1018
R06AE07
ATC
cetirizine; oral
1.6
13.3
416
2933
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
3.7
13.3
58
163
SPAT1254
SPAT
Administration of medicine
2.2
13.2
137
656
M79.6
ICD-10 Finland
Pain in limb
1.7
13.2
322
2116
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.2
13.1
147
729
J05AB01
ATC
aciclovir; systemic
2.0
13.0
177
955
L02BG03
ATC
anastrozole; oral
22.8
12.9
18
8
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
3.2
12.9
68
222
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
3.6
12.8
57
163
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.1
12.8
151
765
F51.0
ICD-10 Finland
Nonorganic insomnia
2.2
12.8
138
672
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.8
12.7
248
1520
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.4
12.7
109
478
R01AD58
ATC
fluticasone, combinations; inhalant, nasal
1.9
12.6
221
1307
J01FA06
ATC
roxithromycin; oral
1.6
12.5
393
2765
E29.0
ICD-10 Finland
Testicular hyperfunction
+∞
12.5
12
*
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.8
12.4
226
1352
E0000UV
ATC
NA
1.6
12.3
361
2491
R50.9
ICD-10 Finland
Fever, unspecified
2.1
12.3
156
816
R51.80
ICD-10 Finland
Headache
2.1
12.3
141
706
N04BC05
ATC
pramipexole; oral
2.9
12.1
72
255
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
2.3
12.1
111
503
N05CD07
ATC
temazepam; oral
2.3
12.1
117
542
AA1AD
NOMESCO Finland
CT of head and brain
1.8
12.0
228
1379
L03
ICPC
Low back symptom/complaint
1.8
12.0
215
1279
R10.1
ICD-10 Finland
Pain localized to upper abdomen
2.1
11.8
138
695
E89.5
ICD-10 Finland
Postprocedural testicular hypofunction
65.6
11.6
13
*
WVA30
SPAT
NA
3.8
11.6
48
130
N06AB03
ATC
fluoxetine; oral
2.2
11.5
126
620
X59
ICD-10 Finland
Exposure to unspecified factor
1.8
11.5
239
1488
J01FA09
ATC
clarithromycin; systemic
1.7
11.5
310
2085
E30.09
ICD-10 Finland
Delayed puberty NOS
+∞
11.5
11
*
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
2.6
11.4
82
324
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
2.9
11.4
70
251
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.7
11.4
258
1650
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
2.5
11.3
91
383
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.6
11.3
329
2258
P06
ICPC
Sleep disturbance
2.2
11.3
112
527
J01MA12
ATC
levofloxacin; systemic
1.8
11.2
193
1129
KFH50
NOMESCO Finland
Insertion of prosthetic replacement for testis
20.2
11.1
16
8
G04CA02
ATC
tamsulosin; oral
1.7
11.0
285
1893
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
2.4
11.0
98
437
E22.1
ICD-10 Finland
Hyperprolactinaemia
43.7
10.9
13
*
H02AB04
ATC
methylprednisolone; systemic
2.0
10.9
138
720
XW000
NOMESCO Finland
Bone marrow biopsy
3.4
10.9
52
158
S50
ICPC
Skin, Medication/prescr/renewal
12.0
10.9
19
16
S55
ICPC
Skin, Local injection/infiltration
15.7
10.8
17
11
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.5
10.8
452
3388
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
1.7
10.8
257
1665
Y05
ICPC
Scrotum/testis sympt/compl other
5.0
10.6
33
68
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
2.9
10.5
63
225
J01FF01
ATC
clindamycin; systemic
1.6
10.5
294
1991
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
3.2
10.5
54
174
N06BA04
ATC
methylphenidate; oral
4.2
10.5
39
96
T29
ICPC
Endocr/metab/nutr sympt/compl other
5.3
10.5
31
60
KE1BE
NOMESCO Finland
Rectal ultrasound examinaiton of prostata
2.1
10.5
118
586
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.7
10.5
245
1578
H01AC01
ATC
somatropin; parenteral
+∞
10.4
10
*
R01BA52
ATC
pseudoephedrine, combinations; oral
1.6
10.4
289
1953
J05AB11
ATC
valaciclovir; oral
2.1
10.4
118
591
J01EA01
ATC
trimethoprim; systemic
2.3
10.3
93
415
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
2.1
10.3
119
596
M04AA01
ATC
allopurinol; systemic
2.0
10.3
141
759
A02BC04
ATC
rabeprazole; oral
2.4
10.1
87
382
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
1.8
10.0
175
1030
NK6MA
NOMESCO Finland
Measurement of bone age from hand and elbow using X-ray
40.4
10.0
12
*
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.9
10.0
152
853
C08CA01
ATC
amlodipine; oral
1.6
9.9
319
2232
SPAT1262
SPAT
Handing over of treatment supplies
1.7
9.9
205
1270
UDC00
NOMESCO Finland
Ear microscopy
2.5
9.9
79
331
C62.12
ICD-10 Finland
Malignant tumor of the descending testicle, embryonic carsinoma, teratocarcinoma or coriocarsinoma
16.9
9.9
15
9
Y99
ICPC
Genital disease male other
12.3
9.9
17
14
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.7
9.7
222
1418
M25.5
ICD-10 Finland
Pain in joint
1.6
9.7
257
1710
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.8
9.7
169
990
R03DC03
ATC
montelukast; oral
1.9
9.7
137
747
SPAT1203
SPAT
Injection therapy, other than intramuscular or subcutaneous
3.4
9.7
45
135
C10AA07
ATC
rosuvastatin; oral
1.7
9.6
243
1593
E66.8
ICD-10 Finland
Other obesity
2.8
9.6
61
226
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.8
9.6
168
984
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.7
9.5
226
1457
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
2.3
9.5
85
379
S01GX01
ATC
cromoglicic acid; ophthalmic
1.8
9.5
165
966
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
2.5
9.5
71
291
UJF32
NOMESCO Finland
Coloscopy
1.7
9.4
222
1426
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
2.5
9.4
74
310
Y55
ICPC
Male Genital, Local injection/infiltration
100.8
9.4
10
*
E23.09
ICD-10 Finland
Pituitary insufficiency NOS
+∞
9.4
9
*
2572A
ICD-9 Finland
Testicular dysfunction, Other testicular hypofunction
+∞
9.4
9
*
R03BA08
ATC
ciclesonide; inhalant
2.4
9.3
77
332
OAB72
NOMESCO Finland
Weight control and weight loss guidance
10.8
9.3
17
16
R06AX22
ATC
ebastine; oral
1.8
9.3
155
897
9061/3-C62.9
ICD-O-3
Seminoma, NOS, of testis, NOS
13.8
9.2
15
11
Z76.0
ICD-10 Finland
Issue of repeat prescription
1.8
9.2
166
984
N06AA12
ATC
doxepin; systemic
2.7
9.2
59
222
N06CA01
ATC
amitriptyline and psycholeptics; systemic
2.3
9.1
86
396
A98
ICPC
Health maint/preventive medicine
2.1
9.1
1112
10491
J01DA01
ATC
[U] cefalexin; systemic
1.5
9.1
621
5107
N06AB05
ATC
paroxetine; oral
2.4
9.1
77
336
R60.0
ICD-10 Finland
Localized oedema
2.2
9.0
88
412
NA2BG
NOMESCO Finland
Thoracal spine MRI examination with high intensity magnet
4.3
9.0
32
76
WX320
NOMESCO Finland
Spinalanesthesy
1.7
9.0
189
1172
J45.9
ICD-10 Finland
Asthma, unspecified
1.8
9.0
151
875
N41.1
ICD-10 Finland
Chronic prostatitis
2.9
9.0
53
189
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
3.1
8.9
47
155
R03AK07
ATC
formoterol and budesonide; inhalant
1.7
8.9
190
1187
WX110
NOMESCO Finland
Local anesthesy
1.5
8.9
745
6370
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.1
8.8
102
515
A06AD11
ATC
lactulose; oral
2.0
8.8
106
544
SAA03
NOMESCO Finland
Extended examination of mouth
1.5
8.8
399
3011
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.6
8.7
277
1923
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
2.7
8.7
57
217
M02AA07
ATC
piroxicam; topical
1.5
8.7
315
2258
H05BX01
ATC
cinacalcet; oral
50.4
8.7
10
*
N06AX22
ATC
agomelatine; oral
4.0
8.7
33
84
C03CA01
ATC
furosemide; systemic
1.7
8.7
180
1116
N02AA05
ATC
oxycodone; systemic
1.9
8.7
121
656
C07AB07
ATC
bisoprolol; oral
1.5
8.7
405
3075
L28
ICPC
Limited function/disability (L)
2.0
8.6
103
526
A03FA01
ATC
metoclopramide; systemic, rectal
1.9
8.6
139
794
UDH02
NOMESCO Finland
Rhinopharyngoscopy
2.3
8.6
79
357
UDQ12
NOMESCO Finland
Flexible laryngoscopy
2.5
8.6
65
267
M54.2
ICD-10 Finland
Cervicalgia
2.4
8.6
72
314
M79.1
ICD-10 Finland
Myalgia
2.0
8.6
105
543
L08
ICPC
Shoulder symptom/complaint
1.8
8.6
169
1029
G04BD12
ATC
mirabegron; oral
2.4
8.5
72
315
SCA01
NOMESCO Finland
Simple analysis and advice of nutrition with regard to dentistry
1.6
8.5
259
1781
N03AE01
ATC
clonazepam; systemic
2.4
8.5
68
289
N05BA01
ATC
diazepam; systemic, rectal
1.8
8.5
140
807
M01AH01
ATC
celecoxib; oral (coxibs)
1.8
8.5
150
885
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.7
8.4
190
1205
Q53.2
ICD-10 Finland
Undescended testicle, bilateral
90.7
8.4
9
*
E23.05
ICD-10 Finland
Lack of TSH
90.7
8.4
9
*
AA4BG
NOMESCO Finland
MRI examination of sella turcica with high intensity magnet
90.7
8.4
9
*
Z01.2
ICD-10 Finland
Dental examination
1.5
8.4
392
2968
E21.09
ICD-10 Finland
Other primary hyperparathyroidism
+∞
8.3
8
*
E23.01
ICD-10 Finland
Isolated deficiency of growth hormone
+∞
8.3
8
*
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.5
8.2
289
2052
M01AX05
ATC
glucosamine; oral
1.9
8.2
116
633
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
3.2
8.2
41
131
M01AB55
ATC
diclofenac, combinations; oral
2.7
8.2
54
207
127
Kela drug reimbursment
Transplant complication
3.9
8.2
32
84
J01AA04
ATC
lymecycline; systemic
1.9
8.2
130
738
SPAT1263
SPAT
Sampling
1.5
8.2
380
2872
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.5
8.1
413
3177
ZXA05
NOMESCO Finland
Left side
1.6
8.1
225
1508
AA4CM
NOMESCO Finland
Extensive MRI examination of sella turcica with 3 Tesla magnet
33.6
8.1
10
*
Y08
ICPC
Sexual function sympt/compl male
6.9
8.1
19
28
75210
ICD-8 Finland
Congenital anomalies of genital organs, Undescended testicle
3.8
8.1
32
85
H02.3
ICD-10 Finland
Blepharochalasis
3.2
8.1
41
133
N03AX09
ATC
lamotrigine; oral
2.5
8.0
61
251
R52.9
ICD-10 Finland
Pain, unspecified
2.3
8.0
75
345
SPAT1310
SPAT
Counselling related to known health issue
1.5
7.9
283
2016
SAA01
NOMESCO Finland
Simple examination of mouth
1.4
7.9
757
6563
A02BA02
ATC
ranitidine; systemic
1.7
7.8
158
970
SPAT1249
SPAT
Treatment-related counselling outside office
1.5
7.8
337
2503
M19.0
ICD-10 Finland
Primary arthrosis of other joints
2.1
7.8
88
438
X58
ICD-10 Finland
Exposure to other specified factors
1.6
7.7
188
1218
I87.2
ICD-10 Finland
Venous insufficiency (chronic)(peripheral)
2.3
7.6
68
305
H02AB07
ATC
prednisone; oral
1.9
7.6
113
626
KFA00
NOMESCO Finland
Exploration of testis
8.1
7.6
16
20
M81.9
ICD-10 Finland
Osteoporosis, unspecified
5.2
7.6
22
43
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
2.1
7.6
84
415
R35
ICD-10 Finland
Polyuria
2.3
7.5
68
309
J01MA01
ATC
ofloxacin; systemic
2.1
7.5
80
391
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.4
7.5
507
4104
M05BA04
ATC
alendronic acid; oral
3.2
7.5
37
118
WX722
NOMESCO Finland
PEEP
2.4
7.5
61
262
R06AX13
ATC
loratadine; oral
1.8
7.5
133
786
G44.2
ICD-10 Finland
Tension-type headache
2.0
7.4
92
477
L01
ICPC
Neck symptom/complaint
1.9
7.4
100
537
R03AC03
ATC
terbutaline; inhalant
1.8
7.3
123
711
R03BA05
ATC
fluticasone; inhalant
1.7
7.3
156
973
G03GA02
ATC
human menopausal gonadotrophin; parenteral
+∞
7.3
7
*
E23.03
ICD-10 Finland
Lack of ACTH
+∞
7.3
7
*
SPAT1325
SPAT
Vaccination
1.5
7.3
244
1708
R05FA02
ATC
opium derivatives and expectorants; systemic
1.5
7.2
342
2582
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.4
7.2
590
4926
KED22
NOMESCO Finland
Transurethral resection of prostate
2.4
7.1
59
255
N06AA09
ATC
amitriptyline; systemic
2.1
7.1
79
392
Z01.1
ICD-10 Finland
Examination of ears and hearing
1.9
7.1
109
612
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
2.1
7.1
83
419
A99
ICPC
Disease/condition unspecnature/site
2.2
7.1
67
309
F34.1
ICD-10 Finland
Dysthymia
2.9
7.1
41
145
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
3.1
7.1
36
118
SAA02
NOMESCO Finland
Basic examination of mouth
1.4
7.0
660
5641
R02
ICPC
Shortness of breath/dyspnoea
1.9
6.9
94
503
SPAT1301
SPAT
No procedures
1.5
6.9
259
1860
L17
ICPC
Foot/toe symptom/complaint
1.6
6.9
193
1292
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.8
6.9
116
671
L03AA02
ATC
filgrastim; parenteral
3.4
6.9
31
93
Y88
ICD-10 Finland
Sequelae with surgical and medical care as external cause
8.3
6.8
14
17
N06AG02
ATC
moclobemide; oral
2.5
6.8
49
199
C09DA03
ATC
valsartan and diuretics; oral
2.6
6.8
48
192
R01AD01
ATC
beclometasone; nasal
1.7
6.8
145
906
N18.8
ICD-10 Finland
Other chronic renal failure
3.0
6.8
36
122
G03GA05
ATC
follitropin alfa; parenteral
40.3
6.8
8
*
B01AB05
ATC
enoxaparin; parenteral
1.5
6.8
234
1648
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
3.4
6.7
30
89
SPAT1312
SPAT
General health counselling
1.5
6.7
272
1981
EP1AE
NOMESCO Finland
Neck ultrasound examination
2.5
6.7
48
194
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
2.2
6.7
69
331
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
2.2
6.7
65
306
C02AC05
ATC
moxonidine; oral
2.6
6.7
45
176
N45.9
ICD-10 Finland
Orchitis, epididymitis and epididymo-orchitis without abscess
2.6
6.7
47
187
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.0
6.7
82
423
R74
ICPC
Upper respiratory infection acute
1.5
6.6
237
1683
NA3EA
NOMESCO Finland
Lumbar spine X-ray examination with flexion
3.0
6.6
36
124
A04
ICPC
Weakness/tiredness general
1.9
6.6
90
487
C62.19
ICD-10 Finland
Malignant tumor of the descending testicle, other or undetermined histology
12.3
6.6
11
9
M54.1
ICD-10 Finland
Radiculopathy
2.6
6.6
44
172
M54.9
ICD-10 Finland
Dorsalgia, unspecified
1.8
6.6
101
570
D07BB04
ATC
hydrocortisone butyrate and antiseptics; topical
1.7
6.5
123
737
C09CA03
ATC
valsartan; oral
2.0
6.5
85
450
OAA65
SPAT
NA
1.8
6.5
118
700
SPAT1094
SPAT
Continuous Positive Airway Pressure
4.2
6.5
23
56
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.0
6.5
77
394
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.9
6.5
89
481
T90
ICPC
Diabetes non-insulin dependent
1.5
6.5
227
1604
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.6
6.5
151
964
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.2
6.4
63
298
AA4DG
NOMESCO Finland
Very extensive MRI examination of sella turcica with high intensity magnet
70.2
6.4
7
*
C91.0
ICD-10 Finland
Acute lymphoblastic leukaemia [ALL]
14.4
6.4
10
7
NJ3CG
NOMESCO Finland
Extensive MRI examination of extremities with median high magnet
14.4
6.4
10
7
ZX120
NOMESCO Finland
Intravenous
2.0
6.4
82
432
D07AC13
ATC
mometasone; topical
1.5
6.4
264
1934
L57.0
ICD-10 Finland
Actinic keratosis
2.3
6.3
57
259
R39.1
ICD-10 Finland
Other difficulties with micturition
2.7
6.3
41
157
N04BC06
ATC
cabergoline; oral (dopamine agonists)
18.1
6.3
9
5
Q53.9
ICD-10 Finland
Undescended testicle, unspecified
+∞
6.3
6
*
Y10
ICPC
Infertility/subfertility male
26.8
6.2
8
*
N01
ICPC
Headache
2.1
6.2
66
323
S46.0
ICD-10 Finland
Injury of muscle(s) and tendon(s) of the rotator cuff of shoulder
1.9
6.2
94
526
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.8
6.2
103
596
G56.0
ICD-10 Finland
Carpal tunnel syndrome
1.8
6.2
105
613
NA1AD
NOMESCO Finland
Cervical spine CT examination
2.5
6.2
45
185
F41.2
ICD-10 Finland
Mixed anxiety and depressive disorder
2.0
6.2
72
366
7525A
ICD-9 Finland
Congenital anomalies of genital organs, Undescended testicle[RETENTIO TESTIS (CRYPTORCHISMUS)]
6.3
6.2
15
24
C08CA13
ATC
lercanidipine; oral
1.8
6.2
103
598
-55
ICPC
Local injection/infiltration
7.7
6.1
13
17
R01AD11
ATC
triamcinolone; nasal
1.9
6.1
80
427
M23.9
ICD-10 Finland
Internal derangement of knee, unspecified
1.9
6.1
88
487
R42
ICD-10 Finland
Dizziness and giddiness
1.6
6.1
146
940
XKD06
NOMESCO Finland
Physiologic investigation of micturition
3.0
6.0
32
109
A07DA03
ATC
loperamide; oral
2.8
6.0
36
132
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
2.3
6.0
52
232
NE1BG
NOMESCO Finland
Pelvic, hip and femur MRI examination with high intensity magnet
3.3
6.0
28
87
N02AJ13
ATC
tramadol and paracetamol; systemic
3.7
6.0
24
66

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: E4_TESTIDYS – Testicular dysfunction

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).