Gout, strict definition

GOUT_STRICT

gout: A condition characterized by painful swelling of the joints, which is caused by deposition of urate crystals.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions

GOUT_IDIOP_NOS

4918

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Filter registries

Medicine purchases: ATC M04AA01|M04AA03|M04AB01|M04AB03

3957

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Check pre-conditions, main-only, mode, ICD version None

3399

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Check minimum number of events

Min. number of events 3

3399

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Include endpoints None

3399

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GOUT_STRICT

Extra metadata

First used in FinnGen datafreeze DF3

Summary Statistics

Key figures

All Female Male
Number of individuals 3290 649 2641
Unadjusted prevalence (%) 1.07 0.37 1.96
Mean age at first event (years) 62.08 65.35 61.27

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.78 [1.29, 2.46] 4.9e-4 695
15 years 0.01 1.30 [0.97, 1.73] 7.6e-2 378
5 years 0.00 1.97 [1.51, 2.57] 4.7e-7 183
1 year 0.00 1.23 [0.76, 1.99] 3.9e-1 22

Correlations

Index endpoint: GOUT_STRICT – Gout, strict definition
GWS hits: 6

Survival analyses between endpoints

Plot

before Gout, strict definition
after Gout, strict definition

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Drugs most likely to be purchased after Gout, strict definition