Hypothyroidism, drug reimbursement

HYPOTHY_REIMB

hypothyroidism: Abnormally low levels of thyroid hormone.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

KELA reimbursements: KELA codes 104

10175

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Check pre-conditions, main-only, mode, ICD version None

10175

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Check minimum number of events None

10175

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Include endpoints None

10175

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HYPOTHY_REIMB

Extra metadata

First used in FinnGen datafreeze DF3

Summary Statistics

Key figures

All Female Male
Number of individuals 9868 8269 1599
Unadjusted prevalence (%) 3.20 4.77 1.18
Mean age at first event (years) 46.86 46.19 50.33

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.01 0.94 [0.77, 1.15] 5.4e-1 648
15 years 0.00 0.69 [0.57, 0.84] 2.2e-4 297
5 years 0.00 0.46 [0.33, 0.65] 1.1e-5 41
1 year 0.00 0.66 [0.35, 1.26] 2.1e-1 10

Correlations

Index endpoint: HYPOTHY_REIMB – Hypothyroidism, drug reimbursement
GWS hits: 12

Survival analyses between endpoints

Plot

before Hypothyroidism, drug reimbursement
after Hypothyroidism, drug reimbursement

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Hypothyroidism, drug reimbursement