ulcerative colitis: An inflammatory bowel disease involving the mucosal surface of the large intestine and rectum. It may present with an acute or slow onset and follows an intermittent or continuous course. Signs and symptoms include abdominal pain, diarrhea, fever, weight loss, and intestinal hemorrhage.
Ulcerative colitis (strict definition, require KELA, min 2 HDR)
DOID EFO Endpoint Browser PheWeb
K11_UC_STRICT2
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditions
|
8123 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
7439 |
4. Check minimum number of eventsNone |
7439 |
5. Include endpointsNone |
7439 |
6. Filter based on genotype QC (FinnGen only) |
7439 |
Control definitions (FinnGen only)
- Control conditions
- not K11_KELAUC
Extra metadata
- Level in the ICD hierarchy
- C
- First used in FinnGen datafreeze
- DF3
- Parent code in ICD-10
- K50-K52
- Name in latin
- Colitis ulcerosa
Similar endpoints
↥List of similar endpoints to
Ulcerative colitis (strict definition, require KELA, min 2 HDR)
based on the number of shared cases.
Similar with more cases:
- Ulcerative colitis (strict definition, require KELA)
- UC patients in KELA-register ( KELA 208 prior to 1994, or ICD K51)
- IBD patients in KELA-register
- Inflammatory bowel disease, strict (require KELA)
- Ulcerative colitis
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 41969 | 18869 | 22911 |
| Only index persons | 39683 | 18151 | 21532 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.59 | 0.54 | 0.64 |
| Only index persons | 0.75 | 0.67 | 0.82 |
| Median age at first event (years) | |||
| Whole population | 37.32 | 36.03 | 38.27 |
| Only index persons | 36.56 | 35.57 | 37.40 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 7439 | 3770 | 3669 |
| Unadjusted period prevalence (%) | 1.45 | 1.29 | 1.62 |
| Median age at first event (years) | 38.35 | 35.00 | 41.78 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 6648
- Matched controls
- 66479
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
5561A
ICD-9 Finland
Idiopathic proctocolitis, Ulcerative (chronic) ileocolitis
+∞
323.0
322
*
J01MA02
ATC
ciprofloxacin; systemic
2.9
323.0
3079
15209
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
4.5
323.0
2865
9544
K51.2
ICD-10 Finland
Ulcerative (chronic) proctitis
274.4
323.0
1788
89
M07.5*K51.9
ICD-10 Finland
Arthropathy in ulcerative colitis
561.6
323.0
322
6
208
Kela drug reimbursment
Ulcerative colitis and Crohn's disease
+∞
323.0
6648
404
L04AX01
ATC
azathioprine; systemic
55.5
323.0
2818
870
K51.9
ICD-10 Finland
Ulcerative colitis, unspecified
364.5
323.0
4072
287
UJF14
NOMESCO Finland
Enteroscopy of ileoanal anastomosis
175.1
323.0
517
32
H02AB06
ATC
prednisolone; systemic
9.0
323.0
5259
19630
A07EC02
ATC
mesalazine; oral, rectal
1873.2
323.0
6326
694
K51.0
ICD-10 Finland
Ulcerative (chronic) pancolitis
341.7
323.0
936
32
L01BB02
ATC
mercaptopurine; oral
79.0
323.0
826
119
326
Kela drug reimbursment
Adalimumab, golimumab, infliximab and ustekinumab (intestinal diseases)
71.1
323.0
567
87
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
11.9
323.0
1788
1998
K50.1
ICD-10 Finland
Crohn disease of large intestine
34.2
323.0
599
192
K51.3
ICD-10 Finland
Ulcerative (chronic) rectosigmoiditis
811.2
323.0
2787
58
56310
ICD-8 Finland
Chronic enteritis and ulcerative colitis, Ulcerative colitis
273.3
323.0
386
15
K51.1
ICD-10 Finland
Ulcerative (chronic) ileocolitis
373.7
323.0
1266
42
K50.9
ICD-10 Finland
Crohn disease, unspecified
23.5
323.0
599
279
A07EA06
ATC
budesonide; oral, local oral
67.5
323.0
2375
543
K51.8
ICD-10 Finland
Other ulcerative colitis
280.3
323.0
1756
85
O99.6
ICD-10 Finland
Diseases of the digestive system complicating pregnancy, childbirth and the puerperium
44.0
323.0
428
104
UJF32
NOMESCO Finland
Coloscopy
22.0
323.0
5003
8060
D94
ICPC
Chronic enteritis/ulcerative colitis
94.0
323.0
528
61
A07EA02
ATC
hydrocortisone; rectal
228.6
323.0
2590
185
H02AB07
ATC
prednisone; oral
6.4
323.0
2056
4340
K51
ICD-10 Finland
Ulcerative colitis
472.9
323.0
1114
28
K50.8
ICD-10 Finland
Other Crohn disease
22.3
323.0
598
294
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
11.2
323.0
826
832
K51.5
ICD-10 Finland
Left sided colitis
761.6
323.0
4278
155
A07EC01
ATC
sulfasalazine; oral, rectal
9.3
323.0
1697
2361
A07EA01
ATC
prednisolone; rectal
255.9
323.0
541
23
UJF30
NOMESCO Finland
Ileoscopy through colon
18.7
323.0
2800
2488
5562A
ICD-9 Finland
Idiopathic proctocolitis, Ulcerative (chronic) proctitis
1621.0
312.6
302
*
P01AB01
ATC
metronidazole; oral, rectal
2.7
307.5
3169
16689
ZX120
NOMESCO Finland
Intravenous
4.8
297.0
1113
2688
JFH30
NOMESCO Finland
Total colectomy, mucosal proctectomy and ileoanal anastomosis without ileostomy
281.1
264.9
269
10
5568X
ICD-9 Finland
Idiopathic proctocolitis, Other ulcerative colitis
517.2
252.5
250
5
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.7
250.2
2171
9991
UJF12
NOMESCO Finland
Enteroscopy through intestinal stoma
96.0
249.4
276
30
K83.0
ICD-10 Finland
Cholangitis
21.3
241.6
364
180
A07EC03
ATC
olsalazine; oral
307.9
233.3
236
8
K52.88
ICD-10 Finland
Other specified noninfective gastroenteritis and colitis
11.4
225.7
439
408
4AA12
NOMESCO Finland
NA
61.3
176.9
208
35
A05AA02
ATC
ursodeoxycholic acid; oral
10.1
174.4
361
376
4AB02
NOMESCO Finland
NA
49.7
174.0
212
44
JFG00
NOMESCO Finland
Closure of loop enterostomy without resection
30.3
172.4
234
80
L04AB04
ATC
adalimumab; parenteral
8.4
170.5
393
493
TPH04
NOMESCO Finland
Cathetrisation of vein
2.5
167.0
1578
7323
WX002
NOMESCO Finland
Sedation and analgesia
2.6
166.9
1458
6474
A02BC02
ATC
pantoprazole; systemic
2.0
165.6
4149
29772
K50.0
ICD-10 Finland
Crohn disease of small intestine
10.5
158.8
321
319
A06AC01
ATC
ispaghula (psylla seeds); oral
2.4
153.1
1612
7863
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.0
142.2
2666
16674
JKE98
NOMESCO Finland
Other transduodenal endoscopic operation on bile duct or ampulla of Vater
11.5
142.0
274
248
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.4
139.1
1393
6576
L04AD01
ATC
ciclosporin; systemic
7.4
126.5
314
440
M07.5
ICD-10 Finland
Arthropathy in ulcerative colitis
425.6
126.3
126
*
1370
FHL
Colonoscopy, whole colon
34.2
119.5
157
47
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
3.0
118.4
750
2682
A07DA03
ATC
loperamide; oral
5.4
118.3
377
733
JFH33
NOMESCO Finland
Total colectomy, mucosal proctectomy, ileoanal anastomosis and ileostomy
203.6
115.9
120
6
JFH10
NOMESCO Finland
Total colectomy and ileostomy
54.8
108.0
129
24
WX302
NOMESCO Finland
Thoracal epidural anesthesy
3.9
107.7
478
1296
UJF92
NOMESCO Finland
Capsular endoscopy
6.4
106.6
295
481
JFH11
NOMESCO Finland
Laparoscopic colectomy
531.3
106.0
105
*
5560A
ICD-9 Finland
Idiopathic proctocolitis, Ulcerative (chronic) enterocolitis
139.8
103.4
110
8
JFA15
NOMESCO Finland
Endoscopic polypectomy in colon
4.3
103.4
408
993
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
3.6
103.2
513
1529
Z93.2
ICD-10 Finland
Ileostomy status
44.2
101.5
126
29
JGB50
NOMESCO Finland
Mucosal proctectomy and ileoanal anastomosis
259.3
100.0
102
*
K62.8
ICD-10 Finland
Other specified diseases of anus and rectum
14.1
95.8
167
121
K62.5
ICD-10 Finland
Haemorrhage of anus and rectum
3.8
94.7
437
1223
253
Kela drug reimbursment
NA
164.0
92.4
97
6
3042
Kela drug reimbursment
NA
164.0
92.4
97
6
K92.1
ICD-10 Finland
Melaena
4.1
92.1
386
992
C05AA08
ATC
fluocortolone; rectal, topical
2.3
90.9
972
4637
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.5
90.1
778
3325
K56.6
ICD-10 Finland
Other and unspecified intestinal obstruction
5.2
89.1
289
572
4AA33
NOMESCO Finland
NA
105.9
86.1
94
9
JFF10
NOMESCO Finland
Loop enterostomy
16.9
82.7
134
81
3005
Kela drug reimbursment
Tofacitinib
29.2
82.2
112
39
JFH20
NOMESCO Finland
Proctocolectomy and ileostomy
92.3
82.1
91
10
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
3.8
80.4
367
1015
H02AB09
ATC
hydrocortisone; systemic
5.0
80.4
272
564
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
2.4
78.6
767
3481
JF1CG
NOMESCO Finland
Extensive MRI of small bowel
10.8
74.6
147
139
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
5.6
72.4
221
407
K51.4
ICD-10 Finland
Inflammatory polyps
189.6
72.3
75
*
L04AB06
ATC
golimumab; parenteral
8.7
68.9
153
180
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
4.9
68.8
237
501
6419
FHL
Other measure in this category
84.3
67.1
75
9
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
4.6
66.2
239
531
3AC01
NOMESCO Finland
NA
7.7
65.4
156
206
L04AA29
ATC
tofacitinib; oral
21.6
64.9
96
45
H02AB04
ATC
methylprednisolone; systemic
2.0
63.6
896
4763
L04AC05
ATC
ustekinumab; parenteral
13.5
62.2
110
83
M09.2*K51.9
ICD-10 Finland
Juvenile arthritis in ulcerative colitis
+∞
61.5
59
*
N02BE01
ATC
paracetamol; systemic, rectal
1.7
61.5
5256
46246
JN1DG
NOMESCO Finland
Very extensive MRI examination of upper part of abdomen with high intensity magnet
5.6
60.8
185
340
A07AA09
ATC
vancomycin; oral
7.4
60.6
149
206
C10AC01
ATC
colestyramine; oral
4.3
59.3
231
553
JL5SB
NOMESCO Finland
Endoscopic retrograd cholangiopancreaticography
6.7
59.2
155
235
JFA98
NOMESCO Finland
Other transluminal endoscopic local operation on intestine
5.6
58.2
177
325
UJK12
NOMESCO Finland
Peroral cholangioscopy
33.4
58.0
76
23
JFG20
NOMESCO Finland
Closure of enterostomy with resection of exteriorised loop
15.5
57.1
95
62
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
2.2
56.6
626
2992
56902
ICD-8 Finland
Other diseases of intestines and peritoneum, Proctitis haemorrhagica (ulcerosa)
70.5
55.2
63
9
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.6
54.2
2139
15502
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.0
54.1
825
4502
D16
ICPC
Rectal bleeding
4.6
53.9
194
430
JL5AG
NOMESCO Finland
Simple MRI examinaiton of bile and pancreas ducts with high intesity magnet
9.1
53.6
115
128
WVA20
NOMESCO Finland
Medicine administration
4.3
53.5
207
493
K56.5
ICD-10 Finland
Intestinal adhesions [bands] with obstruction
5.8
52.2
152
265
A02BC01
ATC
omeprazole; systemic
1.6
50.9
1484
9934
K50
ICD-10 Finland
Crohn disease [regional enteritis]
14.3
50.1
86
61
UJK02
NOMESCO Finland
ERCP
4.4
49.7
186
429
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.9
49.6
789
4362
JL5BG
NOMESCO Finland
MRI examinaiton of bile and pancreas ducts with high intesity magnet
4.0
48.4
202
517
N02AX02
ATC
tramadol; systemic, rectal
1.5
48.0
2315
17445
1490
FHL
Sigmoideoscopy (fiberscope)
24.5
48.0
68
28
J01MA12
ATC
levofloxacin; systemic
1.8
47.2
995
6046
JF1DG
NOMESCO Finland
Small bowel very extensive MRI with with high intensity magnet
11.7
46.5
87
75
A02BC03
ATC
lansoprazole; oral
1.6
46.1
1514
10410
JFG73
NOMESCO Finland
Excision of ileal pelvic pouch
236.6
46.0
47
*
L04AA01
ATC
[U] ciclosporin; systemic
5.1
45.8
150
301
M07.4*K50.9
ICD-10 Finland
Arthropathy in Crohn's disease [regional enteritis]
19.3
43.9
67
35
UJG02
NOMESCO Finland
Proctoscopy
4.0
43.3
181
464
UJF34
NOMESCO Finland
Left colonoscopy
9.0
42.9
92
103
L04AA33
ATC
vedolizumab; parenteral
94.7
42.8
47
5
5586X
ICD-9 Finland
Other non-infective gastro-enteritis and colitis[KROONINEN INFLAMMATOORINEN SUOLISTOSAIRAUS, NUD]
115.8
42.8
46
*
N02AJ06
ATC
codeine and paracetamol; systemic
1.5
42.4
2191
16634
A02BC05
ATC
esomeprazole; systemic
1.5
41.8
2184
16608
B01AB05
ATC
enoxaparin; parenteral
1.5
41.6
1516
10644
R50.9
ICD-10 Finland
Fever, unspecified
1.8
41.3
827
4929
Z01.8
ICD-10 Finland
Other specified special examinations
1.6
41.2
1198
7946
JF1BD
NOMESCO Finland
Very extensive small bowel CT
9.3
40.7
86
94
TJF80
NOMESCO Finland
Ostomy education
6.7
40.6
106
161
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
2.3
39.0
396
1812
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.8
39.0
733
4274
JH1CG
NOMESCO Finland
Extensive MRI of perianal area
7.7
36.7
87
115
JN3AD
NOMESCO Finland
Abdominal CT examination
2.1
36.6
432
2114
JFF13
NOMESCO Finland
Terminal enterostomy
17.4
36.2
57
33
K60.3
ICD-10 Finland
Anal fistula
3.6
36.1
168
473
K92.2
ICD-10 Finland
Gastrointestinal haemorrhage, unspecified
3.7
36.1
163
448
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
1.9
36.0
567
3106
6410
FHL
Panprococolectomy and ileostomy
359.3
36.0
36
*
JGB40
NOMESCO Finland
Excision of rectum and end ileostomy
359.3
36.0
36
*
5551A
ICD-9 Finland
Regional enteritis, Large intestine
186.0
35.8
37
*
WX402
NOMESCO Finland
General anaesthesia
1.6
35.7
971
6305
TJJ00
NOMESCO Finland
Percutaneous needle biopsy of liver
14.4
35.4
60
42
Z93
ICD-10 Finland
Artificial opening status
14.4
35.4
60
42
D18
ICPC
Change in faeces/bowel movements
3.7
35.0
157
429
WX408
NOMESCO Finland
General anesthesy, balanced
1.5
34.8
1509
10949
JF2AB
NOMESCO Finland
Colongraphy with X-ray
15.0
34.8
58
39
JHA00
NOMESCO Finland
Anal or perianal incision
4.0
33.7
140
358
K56.7
ICD-10 Finland
Ileus, unspecified
4.8
33.6
115
244
D06BX01
ATC
metronidazole; topical
1.9
33.5
569
3198
56300
ICD-8 Finland
Chronic enteritis and ulcerative colitis, Regional enteritis
50.3
33.4
40
8
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
2.3
33.2
333
1512
A06AC51
ATC
ispaghula, combinations; systemic
2.5
33.1
279
1161
D11
ICPC
Diarrhoea
1.7
32.7
717
4377
M45
ICD-10 Finland
Ankylosing spondylitis
3.1
32.7
182
589
Z98.0
ICD-10 Finland
Intestinal bypass and anastomosis status
10.1
32.5
65
65
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
2.2
32.4
350
1646
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.4
31.6
2600
21188
JF1AB
NOMESCO Finland
Passage examination of small bowell with X-ray
4.7
31.1
109
237
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.6
30.7
951
6367
D12.6
ICD-10 Finland
Benign neoplasm: Colon, unspecified
2.5
30.5
251
1034
J01DB01
ATC
cefalexin; oral
1.4
30.2
5049
46029
K61.0
ICD-10 Finland
Anal abscess
3.3
29.9
153
466
UJF30
SPAT
NA
8.4
29.8
66
79
56399
ICD-8 Finland
Chronic enteritis and ulcerative colitis, Other
25.8
29.6
41
16
K91.4
ICD-10 Finland
Colostomy and enterostomy malfunction
17.8
29.6
46
26
JFG40
NOMESCO Finland
Revision of enterostomy or colostomy without laparotomy
12.8
29.2
52
41
1380
FHL
Colonoscopy, left side
31.8
29.0
38
12
K83.8
ICD-10 Finland
Other specified diseases of biliary tract
15.8
28.9
47
30
C05AA01
ATC
hydrocortisone; rectal, topical
2.3
28.8
278
1242
5552A
ICD-9 Finland
Regional enteritis, Small intestine with large intestine
80.5
28.7
32
*
UJF02
NOMESCO Finland
Peroral enteroscopy
7.9
28.3
65
83
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
2.4
28.1
244
1033
601
Kela drug reimbursment
Severe malabsorption of nutrients, mainly fats
5.2
28.0
88
171
5761C
ICD-9 Finland
Other disorders of biliary tract, Cholangitis[CHOLANGITIS SCLEROSIVA]
282.7
27.8
28
*
E0000UV
ATC
NA
1.4
27.7
2209
17794
K59.1
ICD-10 Finland
Functional diarrhoea
2.2
27.6
284
1307
6525
FHL
Enterostomy occlusion
28.6
27.5
37
13
NA6BG
NOMESCO Finland
Sacro-iliac joint MRI examination with high intensity magnet
3.4
27.5
136
404
R19.8
ICD-10 Finland
Other specified symptoms and signs involving the digestive system and abdomen
4.5
27.5
98
218
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.5
27.1
1107
7874
D07AC01
ATC
betamethasone; topical
1.4
26.9
1793
14003
SPAT1262
SPAT
Handing over of treatment supplies
1.5
26.8
889
6032
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
2.9
26.8
168
591
5563A
ICD-9 Finland
Idiopathic proctocolitis, Ulcerative (chronic) proctosigmoiditis
272.1
26.7
27
*
L01BA01
ATC
methotrexate; systemic (folic acid analog.)
2.4
26.7
226
944
0093A
ICD-9 Finland
Ill-defined intestinal infections, Diarrhoea of presumed infectious origin
3.9
26.5
111
288
QBB10
NOMESCO Finland
Major dressing of wound of skin of trunk
2.5
26.5
218
898
JHD00
NOMESCO Finland
Anal dilatation
5.8
25.8
74
129
M05BA04
ATC
alendronic acid; oral
2.1
25.8
291
1395
UJD02
NOMESCO Finland
Gastroscopy
2.3
25.6
240
1057
K55.9
ICD-10 Finland
Vascular disorder of intestine, unspecified
14.6
25.1
42
29
ZXC86
NOMESCO Finland
Use of endoscopic device
6.9
24.9
62
90
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
1.9
24.7
379
2052
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
2.0
24.4
334
1737
K76.9
ICD-10 Finland
Liver disease, unspecified
3.7
23.2
104
287
JAH00
NOMESCO Finland
Laparotomy
2.7
23.0
160
601
JFA58
NOMESCO Finland
Endoscopic dilatation of colon
11.1
22.8
43
39
WW200
NOMESCO Finland
Immunization
2.5
22.8
185
758
A03CA02
ATC
clidinium and psycholeptics; oral
2.1
22.7
265
1291
6408
FHL
Colectomy and ileostomy
230.7
22.6
23
*
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.7
22.5
542
3383
K73.2
ICD-10 Finland
Chronic active hepatitis, not elsewhere classified
8.4
22.3
49
59
Z94.4
ICD-10 Finland
Liver transplant status
8.5
22.0
48
57
JF1AD
NOMESCO Finland
Small bowel CT
6.8
21.5
54
80
SPAT1263
SPAT
Sampling
1.3
21.3
2315
19327
J01FA10
ATC
azithromycin; systemic
1.3
21.3
3502
30890
R01AD08
ATC
fluticasone; nasal
1.4
21.3
1576
12434
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.3
21.1
2119
17486
JFB00
NOMESCO Finland
Partial resection of small intestine
3.6
21.1
96
269
OAB74
NOMESCO Finland
Nutritional guidance related to treatment and rehabilitation for medical condition
5.2
21.1
65
125
JL5CG
NOMESCO Finland
Extensive MRI examinaiton of bile and pancreas ducts with high intesity magnet
4.6
20.7
72
158
JJC00
NOMESCO Finland
Allogenic transplantation of liver
11.2
20.4
38
34
E86
ICD-10 Finland
Volume depletion
3.1
20.3
112
364
A07AA02
ATC
nystatin; oral
2.0
20.0
277
1447
K74.3
ICD-10 Finland
Primary biliary cirrhosis
6.5
20.0
52
81
JN1BG
NOMESCO Finland
MRI examination of upper part of abodmen with high intensity magnet
4.6
19.6
68
149
K56.0
ICD-10 Finland
Paralytic ileus
4.5
19.6
70
158
JFF11
NOMESCO Finland
Laparoscopic loop enterostomy
9.8
19.5
39
40
UJH02
NOMESCO Finland
Anoscopy
2.1
19.5
223
1079
JFH00
NOMESCO Finland
Total colectomy and ileorectal anastomosis
13.8
19.5
33
24
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
2.5
19.3
151
610
Y0599
ICD-8 Finland
Investigation of digestive system
3.4
19.2
94
280
K83.9
ICD-10 Finland
Disease of biliary tract, unspecified
8.0
19.2
43
54
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
1.7
19.1
414
2509
M01AE01
ATC
ibuprofen; systemic, rectal
0.8
18.8
5078
53893
XX6XT
NOMESCO Finland
Other intravascular therapy with radiological guidance
6.2
18.7
50
81
D99
ICPC
Disease digestive system other
4.0
18.7
74
185
D12.3
ICD-10 Finland
Benign neoplasm: Transverse colon
2.9
18.4
112
388
1300
FHL
Esophagogastroduodenoscopy (also includes staining)
4.4
18.4
66
150
A49.9
ICD-10 Finland
Bacterial infection, unspecified
1.6
18.3
437
2722
K43.9
ICD-10 Finland
Other and unspecified ventral hernia without obstruction or gangrene
2.1
18.1
212
1037
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.6
17.5
458
2918
JKE32
NOMESCO Finland
Endoscopic dilatation of bile duct
8.4
17.1
37
44
K52.80
ICD-10 Finland
(Hemorrhagic) colitis caused by antibiotics
9.8
17.1
34
35
UJF32
SPAT
NA
3.1
16.9
92
298
5604
FHL
Vascular preparation or cannulation in the operating room
8.6
16.9
36
42
Z43.2
ICD-10 Finland
Attention to ileostomy
10.0
16.9
33
33
J05AB01
ATC
aciclovir; systemic
1.4
16.8
1019
7748
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.3
16.7
1757
14488
JGB61
NOMESCO Finland
Laparoscopic excision of rectum and ileoanal anastomosis
+∞
16.7
16
*
D64.9
ICD-10 Finland
Anaemia, unspecified
1.7
16.6
373
2282
JKD20
NOMESCO Finland
Anastomosis of bile duct to jejunum
20.1
16.4
24
12
K83.1
ICD-10 Finland
Obstruction of bile duct
3.9
16.3
66
169
TPH07
NOMESCO Finland
Cathetrisation of artery
1.6
16.3
429
2743
D07AD01
ATC
clobetasol; topical
1.4
16.2
732
5277
JJ9AE
NOMESCO Finland
Ultrasound examination of liver transplant
11.6
16.0
29
25
D07AC13
ATC
mometasone; topical
1.3
16.0
1462
11821
J02AC01
ATC
fluconazole; systemic
1.3
15.9
2022
17062
JHD33
NOMESCO Finland
Completing incision of fistula-in-ano
7.7
15.8
36
47
A02BA02
ATC
ranitidine; systemic
1.4
15.7
821
6075
JKE02
NOMESCO Finland
Transduodenal endoscopic incision of common bile duct orifice
3.4
15.6
74
217
JAP00
NOMESCO Finland
Freeing of adhesions in the peritoneal cavity
3.9
15.4
63
163
D29
ICPC
Digestive symptom/complaint other
2.7
15.4
102
376
K75.9
ICD-10 Finland
Inflammatory liver disease, unspecified
3.4
15.4
74
219
D01
ICPC
Abdominal pain/cramps general
1.5
15.4
544
3727
D12.2
ICD-10 Finland
Benign neoplasm: Ascending colon
2.5
15.1
118
478
SPAT1131
SPAT
Colonoscopy
2.2
15.1
152
699
K76.0
ICD-10 Finland
Fatty (change of) liver, not elsewhere classified
2.3
15.1
135
585
1470
FHL
Rectoscopy
5.3
15.0
45
85
K62.4
ICD-10 Finland
Stenosis of anus and rectum
9.4
14.9
30
32
I84.2
ICD-10 Finland
Internal hemorrhoids without complication
1.7
14.9
343
2117
R01AD12
ATC
fluticasone furoate; nasal
1.3
14.8
1665
13807
SPAT1255
SPAT
Intravenous administration of medicine
1.7
14.8
305
1821
JHW96
NOMESCO Finland
Other operation on anus or perianal tissue
5.1
14.8
46
91
JFA38
NOMESCO Finland
Endoscopic dilatation of small intestine
16.5
14.7
23
14
JFG50
NOMESCO Finland
Laparotomy with revision of enterostomy or colostomy
25.1
14.7
20
8
L88
ICD-10 Finland
Pyoderma gangrenosum
9.1
14.6
30
33
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
1.6
14.6
433
2849
XJW99
NOMESCO Finland
Other investigative procedure on digestive system
7.5
14.4
33
44
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.2
14.4
2261
19503
J01AA02
ATC
doxycycline; systemic
1.2
14.2
4296
39701
J05AB11
ATC
valaciclovir; oral
1.4
14.0
609
4351
M46.1
ICD-10 Finland
Sacroiliitis, not elsewhere classified
2.8
14.0
91
332
D12.8
ICD-10 Finland
Benign neoplasm: Rectum
2.1
13.9
160
778
WZC30
NOMESCO Finland
Teaching
1.4
13.9
606
4333
JHD20
NOMESCO Finland
Incision of fistula-in-ano
3.1
13.9
76
249
R74.0
ICD-10 Finland
Elevation of levels of transaminase and lactic acid dehydrogenase [LDH]
2.6
13.8
99
384
B80
ICPC
Iron deficiency anaemia
2.5
13.8
105
419
M13.9
ICD-10 Finland
Arthritis, unspecified
1.6
13.7
336
2105
E27.3
ICD-10 Finland
Drug-induced adrenocortical insufficiency
6.2
13.7
36
58
B03BA03
ATC
hydroxocobalamin; parenteral
1.8
13.7
216
1186
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
1.7
13.6
268
1580
A98
ICPC
Health maint/preventive medicine
1.5
13.6
6236
60591
E000001
ATC
NA
1.3
13.6
1070
8445
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
1.6
13.6
318
1970
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.5
13.6
418
2775
Z35.8
ICD-10 Finland
Supervision of other high-risk pregnancies
1.5
13.6
406
2680
JFH31
NOMESCO Finland
Laparoscopic total colectomy, mucosal proctectomy and ileoanal anastomosis without ileostomy
+∞
13.5
13
*
6522
FHL
Ileostomy
140.3
13.4
14
*
L01BB01
ATC
NA
9.7
13.2
26
27
R01AD09
ATC
mometasone; nasal
1.2
12.9
2487
21853
JHD30
NOMESCO Finland
Incomplete incision of fistula-in-ano
6.4
12.9
33
52
JFA76
NOMESCO Finland
Closure of fistula of small intestine
50.1
12.8
15
*
K73.9
ICD-10 Finland
Chronic hepatitis, unspecified
6.1
12.8
34
56
JAD30
NOMESCO Finland
Repair of incisional hernia using prosthetic material
2.7
12.8
84
308
M07.4
ICD-10 Finland
Arthropathy in Crohn disease [regional enteritis]
11.5
12.8
23
20
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
1.6
12.8
316
1987
JJ1LE
NOMESCO Finland
Ultrasound elastography of liver
3.5
12.7
58
167
5559X
ICD-9 Finland
Regional enteritis, Unspecified site
70.0
12.6
14
*
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
1.9
12.6
180
956
J01DA01
ATC
[U] cefalexin; systemic
1.2
12.5
3486
31739
J01CA04
ATC
amoxicillin; systemic
1.2
12.5
4950
46688
D12.0
ICD-10 Finland
Benign neoplasm: Caecum
2.5
12.3
94
379
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.2
12.2
1699
14394
-
ICD-10 Finland
NA
2.2
12.2
121
553
QBE15
NOMESCO Finland
Excision of other superficial lesion of skin of trunk
5.6
12.0
34
61
A07AA11
ATC
rifaximin; oral
8.2
12.0
26
32
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
1.8
11.9
187
1026
Z90.4
ICD-10 Finland
Acquired absence of other parts of digestive tract
46.7
11.9
14
*
J01FA06
ATC
roxithromycin; oral
1.2
11.8
2029
17581
JHB30
NOMESCO Finland
Rubber band ligature of haemorrhoids or prolapse of mucosa
1.7
11.7
252
1528
D07AB02
ATC
hydrocortisone butyrate; topical
1.3
11.7
1383
11492
JJ5AT
NOMESCO Finland
NA
12.5
11.6
20
16
6437
FHL
Rectum resection and sphincter-sparing through-anastomosis
+∞
11.5
11
*
K90.0
ICD-10 Finland
Coeliac disease
2.0
11.4
140
703
T81.8
ICD-10 Finland
Other complications of procedures, not elsewhere classified
2.4
11.4
97
414
M03BC51
ATC
orphenadrine, combinations; systemic
1.2
11.4
1412
11798
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.4
11.4
571
4190
S18
ICPC
Laceration/cut
1.2
11.3
1954
16916
RD210
NOMESCO Finland
NA
2.3
11.3
107
479
SPAT1153
SPAT
Removal of sutures
1.2
11.3
1408
11768
M46.9
ICD-10 Finland
Inflammatory spondylopathy, unspecified
2.8
11.1
70
254
M81.4
ICD-10 Finland
Drug-induced osteoporosis
6.4
11.0
28
44
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
1.9
11.0
154
815
B02.9
ICD-10 Finland
Zoster without complication
1.7
11.0
215
1268
D07BB04
ATC
hydrocortisone butyrate and antiseptics; topical
1.4
11.0
623
4667
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.3
10.9
913
7251
M09.1*K50.9
ICD-10 Finland
Juvenile arthritis in Crohn's disease [regional enteritis]
43.4
10.9
13
*
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
1.9
10.9
149
782
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.2
10.9
1557
13203
A03BA03
ATC
hyoscyamine; oral
3.8
10.8
44
116
L52
ICD-10 Finland
Erythema nodosum
3.7
10.8
45
121
D07XC01
ATC
betamethasone, combinations; topical
1.4
10.8
532
3891
J01FA09
ATC
clarithromycin; systemic
1.2
10.8
1631
13916
N11.9
ICD-10 Finland
Chronic tubulo-interstitial nephritis, unspecified
6.1
10.7
28
46
JD1AB
NOMESCO Finland
Gastro-duodenography with X-ray
17.8
10.7
16
9
SPAT1249
SPAT
Treatment-related counselling outside office
1.2
10.7
2038
17797
L04AB02
ATC
infliximab; parenteral
60.1
10.6
12
*
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
1.5
10.6
352
2379
WX110
NOMESCO Finland
Local anesthesy
1.2
10.5
4050
37694
Z98.8
ICD-10 Finland
Other specified postsurgical states
2.7
10.4
70
263
JGB60
NOMESCO Finland
Excision of rectum and ileoanal anastomosis
+∞
10.4
10
*
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
1.2
10.4
1358
11396
B01AB10
ATC
tinzaparin; parenteral
1.6
10.4
277
1782
K29.3
ICD-10 Finland
Chronic superficial gastritis
2.0
10.4
125
625
SAA01
NOMESCO Finland
Simple examination of mouth
1.2
10.4
4206
39298
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
1.4
10.3
456
3269
A04.9
ICD-10 Finland
Bacterial intestinal infection, unspecified
3.7
10.2
43
117
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
0.6
10.2
182
2882
WW500
NOMESCO Finland
Blood transfusion
1.8
10.1
166
928
N17.9
ICD-10 Finland
Acute renal failure, unspecified
1.9
10.1
134
695
J01MA01
ATC
ofloxacin; systemic
1.5
10.1
333
2246
K61.1
ICD-10 Finland
Rectal abscess
4.7
10.1
33
71
K85.9
ICD-10 Finland
Acute pancreatitis, unspecified
2.3
10.0
90
396
N03AX16
ATC
pregabalin; oral
1.3
9.9
1040
8498
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
1.6
9.9
222
1365
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
1.7
9.9
208
1255
K85.8
ICD-10 Finland
Other acute pancreatitis
3.8
9.8
40
106
5589X
ICD-9 Finland
Other non-infective gastro-enteritis and colitis, Other and unspecified non-infectious gastro-enteritis and colitis
8.1
9.8
21
26
R03AC02
ATC
salbutamol; inhalant
1.2
9.8
2788
25205
SPAT1325
SPAT
Vaccination
1.2
9.8
1487
12672
JG1JB
NOMESCO Finland
Defekography with X-ray
3.7
9.7
41
112
M25.5
ICD-10 Finland
Pain in joint
1.2
9.7
1379
11668
R11
ICD-10 Finland
Nausea and vomiting
1.5
9.7
338
2315
N82.2
ICD-10 Finland
Fistula of vagina to small intestine
55.1
9.6
11
*
JFA45
NOMESCO Finland
Endoscopic contact coagulation in colon
5.3
9.6
28
53
R4190
NOMESCO Finland
Nutritional therapy
1.8
9.6
170
975
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.3
9.6
1061
8729
TJD00
NOMESCO Finland
Insertion of nasogastric or naso-gastroduodenal tube
2.7
9.5
62
231
N82.3
ICD-10 Finland
Fistula of vagina to large intestine
9.1
9.5
19
21
K52.1
ICD-10 Finland
Toxic gastroenteritis and colitis
10.0
9.5
18
18
N05CF01
ATC
zopiclone; oral
1.2
9.5
1386
11758
56500
ICD-8 Finland
Anal fissure and fistula, Anal fissure
3.7
9.5
40
110
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.2
9.4
1428
12160
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
1.5
9.4
298
1998
J01MA14
ATC
moxifloxacin; systemic
1.4
9.4
373
2618
K83.3
ICD-10 Finland
Fistula of bile duct
30.0
9.4
12
*
4AC05
NOMESCO Finland
NA
30.0
9.4
12
*
WZA90
NOMESCO Finland
Other doctors statement
1.2
9.4
1169
9742
JFG70
NOMESCO Finland
Conversion of continent ileostomy to conventional ileostomy
+∞
9.4
9
*
M075, K515
ICD-10 Finland
NA
+∞
9.4
9
*
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
1.9
9.4
134
716
A01AB09
ATC
miconazole; local oral
1.5
9.3
341
2358
SAA02
NOMESCO Finland
Basic examination of mouth
1.2
9.2
3850
35858
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.2
9.2
2569
23139
K60.4
ICD-10 Finland
Rectal fistula
6.4
9.2
23
36
K55.1
ICD-10 Finland
Chronic vascular disorders of intestine
13.7
9.2
15
11
5550A
ICD-9 Finland
Regional enteritis, Small intestine
13.7
9.2
15
11
S01BA04
ATC
prednisolone; ophthalmic (corticosteroids, plain)
2.2
9.1
92
428
5781A
ICD-9 Finland
Gastro-intestinal haemorrhage, Melaena[MELAENA]
7.7
9.1
20
26
F29
ICD-10 Finland
Unspecified nonorganic psychosis
0.5
9.1
76
1459
D12.5
ICD-10 Finland
Benign neoplasm: Sigmoid colon
1.8
9.1
147
821
JGB96
NOMESCO Finland
Other proctectomy or excision of rectum
11.5
9.0
16
14
JH1CM
NOMESCO Finland
Perianal extensive MRI with 3 Tesla magnet
11.5
9.0
16
14
6455
FHL
Perianal fistula surgery
5.1
9.0
27
53
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
1.2
9.0
3001
27424
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.3
9.0
800
6402
71240
ICD-8 Finland
Rheumatoid arthritis and allied conditions, Spondylitis ankylopoietica
6.5
8.9
22
34
D12.4
ICD-10 Finland
Benign neoplasm: Descending colon
2.5
8.9
65
258
WD315
NOMESCO Finland
Multiple therapy of methastized malignancy with biomodifiers
7.4
8.9
20
27
K52.0
ICD-10 Finland
Gastroenteritis and colitis due to radiation
7.4
8.9
20
27
H20.1
ICD-10 Finland
Chronic iridocyclitis
2.6
8.9
61
234
ZX112
NOMESCO Finland
Subcutaneous
2.1
8.9
96
462
UKC02
NOMESCO Finland
Cystoscopy
1.3
8.9
590
4533
N20.1
ICD-10 Finland
Calculus of ureter
1.7
8.8
165
962
54099
ICD-8 Finland
Acute appendicitis, Without mention of peritonitis
0.3
8.8
25
712
SFA20
NOMESCO Finland
Filling on two surfaces of tooth
1.2
8.8
3304
30459
5781B
ICD-9 Finland
Gastro-intestinal haemorrhage, Melaena[HAEMORRHAGIA EX ANO]
8.6
8.8
18
21
K91.8
ICD-10 Finland
Other postprocedural disorders of digestive system, not elsewhere classified
10.7
8.8
16
15
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.3
8.7
727
5766
DMB20
NOMESCO Finland
Functional endoscopic opening of maxillary antrum
1.5
8.7
258
1705
NA6AA
NOMESCO Finland
Sacro-iliac joint X-ray examination
4.2
8.6
31
74
N11.8
ICD-10 Finland
Other chronic tubulo-interstitial nephritis
6.6
8.6
21
32
-44
ICPC
Preventive immunization/medic
1.5
8.6
322
2233
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
1.5
8.6
309
2127
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.4
8.6
501
3767
T81.3
ICD-10 Finland
Disruption of operation wound, not elsewhere classified
2.0
8.6
101
504
D07BC01
ATC
betamethasone and antiseptics; topical
1.3
8.6
515
3894
JFK10
NOMESCO Finland
Freeing of adhesions in intestinal obstruction
5.5
8.6
24
44
B81
ICPC
Anaemia vit B12/folate deficiency
1.8
8.5
133
734
SPAT1125
SPAT
Stoma care and guidance
2.6
8.5
58
221
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
1.4
8.5
350
2478
K80.3
ICD-10 Finland
Calculus of bile duct with cholangitis
3.6
8.5
36
100
J31.0
ICD-10 Finland
Chronic rhinitis
1.4
8.5
350
2480
N82.4
ICD-10 Finland
Other female intestinal-genital tract fistulae
20.0
8.5
12
6
D07AB08
ATC
desonide; topical
1.4
8.5
483
3621
TDM10
NOMESCO Finland
Puncture of maxillary antrum
1.6
8.4
186
1142
I84.1
ICD-10 Finland
Internal hemorrhoids with other complications
2.0
8.4
101
509
JN1CM
NOMESCO Finland
Upper part of abdomen extensive MRI examination with 3 Tesla magnet
6.7
8.3
20
30
JJC60
NOMESCO Finland
Total excision of transplanted liver
+∞
8.3
8
*
J45.9
ICD-10 Finland
Asthma, unspecified
1.3
8.3
776
6243
WX600
NOMESCO Finland
Single shot through catheter
2.0
8.2
102
518
I80.0
ICD-10 Finland
Phlebitis and thrombophlebitis of superficial vessels of lower extremities
1.8
8.2
145
833
K63.9
ICD-10 Finland
Disease of intestine, unspecified
4.4
8.2
28
64
K43.0
ICD-10 Finland
Incisional hernia with obstruction, without gangrene
3.0
8.2
45
152
S01CA02
ATC
prednisolone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
2.7
8.2
53
198
Z01.2
ICD-10 Finland
Dental examination
1.2
8.1
2233
20032
D62
ICPC
Digestive, Administrative procedure
4.1
8.1
30
74
JJA20
NOMESCO Finland
Open biopsy of liver
5.4
8.1
23
43
K85
ICD-10 Finland
Acute pancreatitis
2.2
8.1
75
338
6403
FHL
Ileocal resection
33.4
8.1
10
*
JFH01
NOMESCO Finland
Laparoscopic colectomy with ileorectal anastomosis
33.4
8.1
10
*
JN3DE
NOMESCO Finland
Abdominal extensive ultrasoudn examination with blood flow measurements after transplantation
3.6
8.0
34
95
JFG96
NOMESCO Finland
Other operation on intestinal stoma or pouch
22.0
8.0
11
5
B25.8
ICD-10 Finland
Other cytomegaloviral diseases
5.0
8.0
24
48
N05AH02
ATC
clozapine; systemic
0.4
8.0
25
681
H15.1
ICD-10 Finland
Episcleritis
2.3
8.0
68
294
J01AA04
ATC
lymecycline; systemic
1.3
7.8
661
5252
WX004
NOMESCO Finland
Patient-controlled sedation
3.3
7.8
36
108
E000002
ATC
NA
1.3
7.8
544
4209
L40.0
ICD-10 Finland
Psoriasis vulgaris
1.6
7.7
193
1225
DNB20
NOMESCO Finland
Endoscopic ethmoidectomy
1.8
7.7
124
692
K83
ICD-10 Finland
Other diseases of biliary tract
45.0
7.7
9
*
56398
ICD-8 Finland
Chronic enteritis and ulcerative colitis, Alia definita
45.0
7.7
9
*
1CB02
NOMESCO Finland
NA
45.0
7.7
9
*
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
1.9
7.7
104
546
WX892
NOMESCO Finland
Monitored bed care
1.4
7.7
300
2104
K02.0
ICD-10 Finland
Caries limited to enamel
1.3
7.7
732
5907
6451
FHL
Dilatation
3.4
7.6
34
99
M03BX02
ATC
tizanidine; oral
1.2
7.6
3418
31788
A02BA03
ATC
famotidine; systemic
1.8
7.6
134
770
6611
FHL
Needle biopsy in the operating room
11.8
7.6
13
11
JN1DM
NOMESCO Finland
Upper part of abdomen very extensive MRI examination with 3 Tesla magnet
11.8
7.6
13
11
M81.9
ICD-10 Finland
Osteoporosis, unspecified
1.9
7.6
101
530
JKE18
NOMESCO Finland
Endoscopic internal drainage of bile duct
3.0
7.5
40
133
NH3EA
NOMESCO Finland
Feet X-ray examination with load
2.0
7.5
95
490
78570
ICD-8 Finland
Symptoms referable to abdomen and lower gastro-intestinal tract, Melaena (not of newborn)
5.4
7.5
21
39
F20.9
ICD-10 Finland
Schizophrenia, unspecified
0.4
7.5
28
709
WX419
NOMESCO Finland
Other general anesthesy
2.5
7.5
53
210
K03.64
ICD-10 Finland
Dental calculus supragingival
1.2
7.4
1480
12899
JFA70
NOMESCO Finland
Suture of small intestine
4.8
7.4
23
48
JFH40
NOMESCO Finland
Proctocolectomy and continent ileostomy
80.2
7.4
8
*
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
1.6
7.3
166
1030
H26.3
ICD-10 Finland
Drug-induced cataract
3.3
7.3
34
103
N02AA05
ATC
oxycodone; systemic
1.3
7.3
495
3819
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
1.6
7.3
174
1096
R06.0
ICD-10 Finland
Dyspnoea
1.2
7.2
989
8310
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.2
7.2
1077
9133
M02AA07
ATC
piroxicam; topical
1.2
7.2
1544
13543
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.3
7.2
662
5316
M80.4
ICD-10 Finland
Drug-induced osteoporosis with pathological fracture
4.6
7.2
23
50
5609X
ICD-9 Finland
Intestinal obstruction without mention of hernia, Unspecified intestinal obstruction
7.3
7.2
16
22
J01FA15
ATC
telithromycin; oral
1.3
7.1
445
3391
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.3
7.1
754
6165
D07CA01
ATC
hydrocortisone and antibiotics; topical
1.3
7.1
598
4751
6402
FHL
Small bowel resection
7.9
7.1
15
19
JAG41
NOMESCO Finland
Repair of stomal hernia, laparoscopic
12.0
7.1
12
10
O99.0
ICD-10 Finland
Anaemia complicating pregnancy, childbirth and the puerperium
2.5
7.1
51
205
SDA02
NOMESCO Finland
Parodonthologic therapy
1.2
7.0
1671
14778
JF1DM
NOMESCO Finland
Very extensive MRI of small bowel (more than 1.5 T)
10.0
7.0
13
13
R01BA52
ATC
pseudoephedrine, combinations; oral
1.2
7.0
1429
12478
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
1.7
7.0
132
780
L71.9
ICD-10 Finland
Rosacea, unspecified
1.9
7.0
90
468
SAA03
NOMESCO Finland
Extended examination of mouth
1.2
6.9
2119
19116
K62.6
ICD-10 Finland
Ulcer of anus and rectum
2.7
6.9
45
170
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.1
6.9
2988
27640
JGA05
NOMESCO Finland
Endoscopic polypectomy in rectum
3.9
6.8
26
67
K92.9
ICD-10 Finland
Disease of digestive system, unspecified
3.6
6.8
28
77
R4110
NOMESCO Finland
Physiotherapy
1.2
6.8
1171
10065
L88
ICPC
Rheumatoid/seropositive arthritis
1.6
6.8
146
894
R06AE07
ATC
cetirizine; oral
1.2
6.8
2317
21062
XF400
NOMESCO Finland
ECG with 12 standard connections
1.3
6.8
625
5019
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
1.4
6.8
285
2032
K83.2
ICD-10 Finland
Perforation of bile duct
40.1
6.8
8
*
N05AH03
ATC
olanzapine; systemic
0.7
6.7
152
2284
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.2
6.7
1038
8829
A04.6
ICD-10 Finland
Enteritis due to Yersinia enterocolitica
7.2
6.7
15
21
R03DC03
ATC
montelukast; oral
1.2
6.6
730
5989
SPAT1104
SPAT
Monitoring of emergency patient
1.4
6.6
255
1787
B82
ICPC
Anaemia other/unspecified
2.0
6.6
81
414
R51.80
ICD-10 Finland
Headache
1.3
6.6
702
5736
JFA56
NOMESCO Finland
Faecal microbiota transplantation
7.8
6.6
14
18
SPAT1301
SPAT
No procedures
1.2
6.6
1443
12666
K62.9
ICD-10 Finland
Disease of anus and rectum, unspecified
3.1
6.5
33
107
D07AA02
ATC
hydrocortisone; topical
1.3
6.5
660
5360
JHA20
NOMESCO Finland
Excision of lesion of anal canal or perianal tissue
2.3
6.5
54
234
XQ800
NOMESCO Finland
Prick test
1.4
6.5
348
2589
SHA01
NOMESCO Finland
Correction of physiology of bite - simple therapy visit
1.3
6.5
498
3905
R2110
NOMESCO Finland
Giving the first information
1.4
6.5
310
2262
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.3
6.5
475
3704
UGC12
NOMESCO Finland
Flexible bronchoscopy
1.4
6.5
264
1870
R05
ICPC
Cough
1.2
6.4
991
8424
K85.0
ICD-10 Finland
Idiopathic acute pancreatitis
3.0
6.4
34
114
NA6CG
NOMESCO Finland
Sacro-iliac joint extensive MRI examination with high intensity magnet
3.0
6.4
34
114
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.3
6.4
415
3178
R01AD05
ATC
budesonide; nasal
1.4
6.4
342
2543
Z93.3
ICD-10 Finland
Colostomy status
2.9
6.4
37
130
L30.0
ICD-10 Finland
Nummular dermatitis
1.7
6.3
133
810
K13.79
ICD-10 Finland
Change in the oral mucosa UNS
1.9
6.3
91
492
A02BA04
ATC
nizatidine; systemic
1.4
6.3
265
1889
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
1.5
6.3
215
1473
JWW96
NOMESCO Finland
Other reoperation in gastroenterological surgery
5.5
6.3
17
31
K02.1
ICD-10 Finland
Caries of dentine
1.1
6.3
3315
31003
WX720
NOMESCO Finland
Own respiration
1.6
6.3
152
962
E000006
ATC
NA
1.4
6.3
281
2029
K43.5
ICD-10 Finland
Parastomal hernia without obstruction or gangrene
18.0
6.3
9
5
M075, K509
ICD-10 Finland
NA
+∞
6.2
6
*
JFG53
NOMESCO Finland
Revision of ileal pelvic pouch
+∞
6.2
6
*
O996, K515
ICD-10 Finland
NA
+∞
6.2
6
*
M073, K519
ICD-10 Finland
NA
+∞
6.2
6
*
6407
FHL
Colectomy and ileorectostomy
26.7
6.2
8
*
ZX100
NOMESCO Finland
Oral
2.2
6.2
57
259
B01AA03
ATC
warfarin; systemic
1.3
6.2
598
4829
J41.1
ICD-10 Finland
Mucopurulent chronic bronchitis
4.8
6.2
19
40
E000003
ATC
NA
1.5
6.2
199
1346
TPH05
NOMESCO Finland
Open cannulation of peripheral vein
2.8
6.2
37
134
H04.10
ICD-10 Finland
Dry eye syndrome
1.3
6.2
365
2757
JFA42
NOMESCO Finland
Endoscopic injection in colon
5.0
6.2
18
36
K45.8
ICD-10 Finland
Other specified abdominal hernia without obstruction or gangrene
3.2
6.2
29
90
JWA00
NOMESCO Finland
Repair of wound dehiscence in gastroenterological surgery
3.3
6.1
28
85
127
Kela drug reimbursment
Transplant complication
2.0
6.1
71
357
A07EB01
ATC
cromoglicic acid; oral
7.7
6.1
13
17
K85.1
ICD-10 Finland
Biliary acute pancreatitis
2.9
6.1
33
113
JL5AM
NOMESCO Finland
Bile and pancreas ducts simple MRI examination with 3 Tesla magnet
12.5
6.1
10
8
M81.8
ICD-10 Finland
Other osteoporosis
3.0
6.1
32
108
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.2
6.0
839
7060
JFA05
NOMESCO Finland
Endoscopic polypectomy in small intestine
8.6
6.0
12
14
JL5BM
NOMESCO Finland
Bile and pancreas ducts MRI examination with 3 Tesla magnet
8.6
6.0
12
14
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
1.4
6.0
240
1695
K63.3
ICD-10 Finland
Ulcer of intestine
6.7
6.0
14
21
Mortality – FinRegistry
↥Association
Association between endpoint K11_UC_STRICT2 and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| K11_UC_STRICT2 | 1.017 [0.9, 1.15] | 0.782 |
| Birth year | 0.995 [0.99, 1.0] | 0.231 |
During the follow-up period (1.1.1998 — 31.12.2019), 854 out of 14198 females with K11_UC_STRICT2 died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| K11_UC_STRICT2 | 0.958 [0.87, 1.06] | 0.399 |
| Birth year | 0.984 [0.97, 0.99] | < 0.001 |
During the follow-up period (1.1.1998 — 31.12.2019), 1501 out of 17157 males with K11_UC_STRICT2 died.
Mortality risk
Mortality risk for people of age
years, who have K11_UC_STRICT2.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.098% | 0.165% |
| 5 | 0.541% | 1.007% |
| 10 | 1.374% | 2.582% |
| 15 | 2.774% | 4.897% |
| 20 | 4.964% | 8.31% |
Relationships between endpoints
↥Index endpoint: K11_UC_STRICT2 – Ulcerative colitis (strict definition, require KELA, min 2 HDR)
GWS hits: 53
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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