No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
114491 |
4. Check minimum number of eventsNone |
114491 |
5. Include endpoints |
115391 |
6. Filter based on genotype QC (FinnGen only) |
115391 |
Control definitions (FinnGen only)
- Control exclude
- M13_DORSOPATHY
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
Similar endpoints
↥List of similar endpoints to Other dorsopathies, not elsewhere classified based on the number of shared cases.
Similar with more cases:
- Dorsopathies
- Diseases of the musculoskeletal system and connective tissue
- Any event in hilmo or specialist outpatient
Similar with less cases:
Case counts by codes
↥Summary Statistics
↥-FinRegistry-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | |||
Whole population | 842235 | 468842 | 368433 |
Only index persons | 795603 | 447324 | 348279 |
Unadjusted period prevalence (%) | |||
Whole population | 12.01 | 13.43 | 10.29 |
Only index persons | 15.07 | 16.44 | 13.30 |
Median age at first event (years) | |||
Whole population | 50.13 | 51.33 | 48.72 |
Only index persons | 49.50 | 50.63 | 48.05 |
-FinnGen-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | 115391 | 70468 | 44923 |
Unadjusted period prevalence (%) | 22.38 | 24.02 | 19.80 |
Median age at first event (years) | 51.26 | 49.68 | 53.75 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 10711
- Matched controls
- 71816
Mortality – FinRegistry
↥Association
Association between endpoint M13_DORSOPATHYOTH and mortality.
Females
Parameter | HR [95% CI] | p-value |
---|---|---|
M13_DORSOPATHYOTH | 1.193 [1.1, 1.3] | < 0.001 |
Birth year | 0.991 [0.98, 1.0] | 0.025 |
During the follow-up period (1.1.1998 — 31.12.2019), 53819 out of 393955 females with M13_DORSOPATHYOTH died.
Males
Parameter | HR [95% CI] | p-value |
---|---|---|
M13_DORSOPATHYOTH | 1.22 [1.12, 1.33] | < 0.001 |
Birth year | 0.988 [0.98, 1.0] | 0.004 |
During the follow-up period (1.1.1998 — 31.12.2019), 45669 out of 309610 males with M13_DORSOPATHYOTH died.
Mortality risk
Mortality risk for people of age
years, who have M13_DORSOPATHYOTH.N-year risk | Females | Males |
---|---|---|
1 | 0.083% | 0.191% |
5 | 0.55% | 1.369% |
10 | 1.414% | 3.368% |
15 | 2.645% | 6.16% |
20 | 4.588% | 10.609% |
Relationships between endpoints
↥Index endpoint: M13_DORSOPATHYOTH – Other dorsopathies, not elsewhere classified
GWS hits: 60