Diseases of the musculoskeletal system and connective tissue

M13_MUSCULOSKELETAL

No definition available.

Endpoint definition

FinnGen phenotype data

321302 individuals

diagram downward connector

Apply sex-specific rule None

321302

diagram downward connector

Check conditions None

321302

diagram downward connector
diagram bullet

Filter registries

Hospital Discharge: ICD-10 M00-M99, M90.6*C40.99, M90.6*C41.99
Cause of death: ICD-10 M00-M99, M90.6*C40.99, M90.6*C41.99

166138

diagram downward connector
diagram bullet

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

166138

diagram downward connector

Check minimum number of events None

166138

diagram downward connector
M13_MUSCULOSKELETAL

Extra metadata

Level in the ICD hierarchy 1
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 171120 98589 72531
Unadjusted prevalence (%) 55.46 56.82 53.72
Mean age at first event (years) 46.81 45.51 48.58

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.30 [1.21, 1.40] 7.0e-12 14542
15 years 0.01 0.91 [0.85, 0.98] 1.1e-2 6938
5 years 0.00 1.49 [1.38, 1.60] 4.4e-28 2833
1 year 0.00 2.93 [2.60, 3.31] 1.3e-69 1043

Cumulative Incidence

Correlations

Index endpoint: M13_MUSCULOSKELETAL – Diseases of the musculoskeletal system and connective tissue
GWS hits: 12

Survival analyses between endpoints

Plot

before Diseases of the musculoskeletal system and connective tissue
after Diseases of the musculoskeletal system and connective tissue

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Diseases of the musculoskeletal system and connective tissue