Polyarthropathies

M13_POLYARTHROPATHIES

obsolete_juvenile idiopathic arthritis: ['A group of chronic, inflammatory childhood disorders of unknown etiology that primarily involve joints.']

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Hospital Discharge: ICD-10 M05-M14
Cause of death: ICD-10 M05-M14

22818

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

22818

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Check minimum number of events None

22818

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M13_POLYARTHROPATHIES

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Similar endpoints

List of similar endpoints to Polyarthropathies based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

Key figures

All Female Male
Number of individuals 24310 13314 10996
Unadjusted prevalence (%) 7.88 7.67 8.14
Mean age at first event (years) 52.52 49.33 56.39

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 2.31 [2.02, 2.66] 1.0e-32 2857
15 years 0.01 1.35 [1.19, 1.54] 6.2e-6 1211
5 years 0.00 2.78 [2.48, 3.12] 3.1e-69 800
1 year 0.00 6.28 [5.40, 7.31] <1e-100 370

Cumulative Incidence

Correlations

Index endpoint: M13_POLYARTHROPATHIES – Polyarthropathies
GWS hits: 14

Survival analyses between endpoints

Plot

before Polyarthropathies
after Polyarthropathies

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Drugs most likely to be purchased after Polyarthropathies