Psoriasis (vulgaris), strict definition

PSORI_STRICT

psoriasis: An autoimmune condition characterized by red, well-delineated plaques with silvery scales that are usually on the extensor surfaces and scalp. They can occasionally present with these manifestations: pustules; erythema and scaling in intertriginous areas, and erythroderma, that are often distributed on extensor surfaces and scalp.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions

L12_PSORI_VULG

4496

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Filter registries

KELA reimbursements: KELA codes 319|377|134

556

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Check pre-conditions, main-only, mode, ICD version None

556

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Check minimum number of events None

556

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Include endpoints None

556

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PSORI_STRICT

Extra metadata

First used in FinnGen datafreeze DF3

Summary Statistics

Key figures

All Female Male
Number of individuals 535 199 336
Unadjusted prevalence (%) 0.17 0.11 0.25
Mean age at first event (years) 51.13 51.40 50.96

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.69 [0.70, 4.10] 2.4e-1 23
15 years 0.01 1.01 [0.38, 2.70] 9.9e-1 12
5 years - - - -
1 year - - - -

Correlations

Index endpoint: PSORI_STRICT – Psoriasis (vulgaris), strict definition
GWS hits: 3

Survival analyses between endpoints

Plot

before Psoriasis (vulgaris), strict definition
after Psoriasis (vulgaris), strict definition

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Drugs most likely to be purchased after Psoriasis (vulgaris), strict definition