This is a non-core endpoint: only basic statistics are computed.
See its core counterpart C3_EYE_ADNEXA_EXALLC for full statistics.
Malignant neoplasm of eye and adnexa
C3_EYE_ADNEXA
No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
287 |
4. Check minimum number of eventsNone |
287 |
5. Include endpointsNone |
287 |
6. Filter based on genotype QC (FinnGen only) |
287 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF9
Similar endpoints
↥List of similar endpoints to
Malignant neoplasm of eye and adnexa
based on the number of shared cases.
Similar with more cases:
- Malignant neoplasm of eye and adnexa, excluding all cancers (controls excluding all cancers)
- Malignant neoplasm of eye, brain and central nervous system
- Malignant neoplasm of eye, brain and central nervous system, excluding all cancers (controls excluding all cancers)
- Malignant neoplasm
- Any event in cancer register
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded from FinRegistry analyses (omitted endpoint).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 287 | 133 | 154 |
| Unadjusted period prevalence (%) | 0.06 | 0.05 | 0.07 |
| Median age at first event (years) | 60.01 | 58.25 | 61.53 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 259
- Matched controls
- 2589
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
C69.30
ICD-10 Finland
Malignant tumor of the chorioidea without histology
2699.6
153.2
133
*
CKE65
NOMESCO Finland
Removal of brachytherapeutic plate from eye
2176.3
134.9
119
*
CKE60
NOMESCO Finland
Brachytherapy of choroid and retina
2176.3
134.9
119
*
XCD10
NOMESCO Finland
Electrophysiological examination of eye
104.9
119.8
126
23
C69.32
ICD-10 Finland
Malignant tumor of the chorioidea melanoma
1803.5
119.7
107
*
CK2L4
NOMESCO Finland
Wide-field/panoramic imaging of ocular fundus
336.8
75.7
73
*
WX140
NOMESCO Finland
Parabulbar anesthesy
28.3
72.0
101
57
C69.3
ICD-10 Finland
Malignant neoplasm: Choroid
+∞
71.2
65
*
XCK10
NOMESCO Finland
Photography of fundus of eye
15.6
70.7
131
159
8720/3-C69.9
ICD-O-3
Malignant melanoma, NOS, of eye, NOS
+∞
70.0
64
*
8720/3-C69.3
ICD-O-3
Malignant melanoma, NOS, of choroid
+∞
67.7
62
*
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
12.8
47.3
91
105
C69.39
ICD-10 Finland
Malignant tumor in chorioidea other or unspecified histology
+∞
37.4
35
*
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
9.4
36.2
82
122
CA1CG
NOMESCO Finland
Eye and orbita extensive MRI examination with high intensity magnet
91.1
35.9
39
5
WX002
NOMESCO Finland
Sedation and analgesia
6.2
35.4
117
302
Z3229
NOMESCO Finland
Other healthcare associate professional
8.4
33.0
80
131
C78.7
ICD-10 Finland
Secondary malignant neoplasm of liver and intrahepatic bile duct
30.1
32.2
43
17
XCW99
NOMESCO Finland
Other investigative procedure of eye
7.3
32.0
86
164
ZXD10
NOMESCO Finland
Scheduled procedure
4.8
31.0
168
721
CFA20
NOMESCO Finland
Biopsy of conjunctiva
168.9
29.3
30
*
C83.80
ICD-10 Finland
B-cell lymphoma in marginal zone
168.9
29.3
30
*
C69.02
ICD-10 Finland
Malignant tumor in conjunctival melanoma
+∞
28.7
27
*
9510/3-C69.2
ICD-O-3
Retinoblastoma, NOS, of retina
+∞
27.6
26
*
ZXA05
NOMESCO Finland
Left side
4.4
26.3
130
482
Z01.0
ICD-10 Finland
Examination of eyes and vision
5.2
25.2
91
243
CAA30
NOMESCO Finland
Biopsy of orbit
275.5
25.1
25
*
Z2221
NOMESCO Finland
Medical doctor
4.2
24.0
123
463
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
8.1
23.3
55
83
CF2S4
NOMESCO Finland
Photography of conjunctiva
+∞
23.3
22
*
C69.00
ICD-10 Finland
Malignant tumor of the conjunctiva without histology
251.3
23.0
23
*
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
26.9
22.8
31
13
ZXA00
NOMESCO Finland
Right side
3.8
21.5
122
489
D31.3
ICD-10 Finland
Benign neoplasm: Choroid
27.0
21.4
29
12
1906B
ICD-9 Finland
Malignant neoplasm of eye, Choroid[MELANOMA CHORIOIDEAE]
+∞
21.1
20
*
ZXE00
NOMESCO Finland
One hour or less
3.5
20.2
147
709
S01ED51
ATC
timolol, combinations; ophthalmic
5.8
18.0
54
112
D31.0
ICD-10 Finland
Benign neoplasm: Conjunctiva
102.2
17.8
19
*
CFC00
NOMESCO Finland
Excision of lesion of conjunctiva
53.9
17.2
20
*
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
3.1
17.1
141
713
C69.21
ICD-10 Finland
Retina
+∞
16.8
16
*
YA1BD
NOMESCO Finland
Extensive CT examination of head and neck for dose design of radiotherapy
29.9
16.8
22
8
CA1DG
NOMESCO Finland
Eye and orbita very extensive MRI examination with high intensity magnet
181.2
16.7
17
*
130
Kela drug reimbursment
Malignant tumour
5.2
16.6
55
128
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
12.0
16.5
30
28
H40.5
ICD-10 Finland
Glaucoma secondary to other eye disorders
28.4
15.9
21
8
9699/3-C69.6
ICD-O-3
Marginal zone B-cell lymphoma, NOS, of orbit, NOS
+∞
15.8
15
*
8000/3-C69.3
ICD-O-3
Neoplasm, malignant of choroid
+∞
15.8
15
*
C69.40
ICD-10 Finland
Malignant tumor of ciliary body without histology
+∞
15.8
15
*
3770
FHL
Placing a radiating plate on the surface of the eye with additional measures
+∞
15.8
15
*
Z51.5
ICD-10 Finland
Palliative care
6.5
15.3
41
73
CKD05
NOMESCO Finland
Puncture of vitreous body with injection of medication
6.2
14.9
41
76
C69.42
ICD-10 Finland
Malignant tumor of ciliary melanoma
+∞
14.7
14
*
3779
FHL
Other operations in this group include disc removal
+∞
14.7
14
*
D31.6
ICD-10 Finland
Benign neoplasm: Orbit, unspecified
158.6
14.6
15
*
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
2.8
14.1
126
646
ZXE10
NOMESCO Finland
More than one and less than three hours
2.8
13.8
129
677
WF002
NOMESCO Finland
Radical radiotherapy
6.8
13.8
35
58
Z90.0
ICD-10 Finland
Acquired absence of part of head and neck
79.4
13.7
15
*
CDC00
NOMESCO Finland
Enucleation of eye
+∞
13.7
13
*
CDC10
NOMESCO Finland
Enucleation of eye with insertion of prosthesis
147.4
13.6
14
*
H26.2
ICD-10 Finland
Complicated cataract
27.5
13.6
18
7
XW000
NOMESCO Finland
Bone marrow biopsy
7.7
13.3
31
45
A03FA01
ATC
metoclopramide; systemic, rectal
3.1
12.8
81
327
L01AX03
ATC
temozolomide; systemic
33.9
12.7
16
5
CD2S4
NOMESCO Finland
Photography of eye
73.6
12.7
14
*
C69.09
ICD-10 Finland
Malignant tumor in conjunctival other or unspecified histology
+∞
12.6
12
*
C69.20
ICD-10 Finland
Retina
+∞
12.6
12
*
CBA10
NOMESCO Finland
Biopsy of eyelid
22.6
12.2
17
8
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
5.9
12.0
34
65
WX142
NOMESCO Finland
Sub-tenon anesthesy
49.1
12.0
14
*
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
12.6
11.5
20
17
C69.03
ICD-10 Finland
Malignant tumor of conjunctival carcinoma
+∞
11.5
11
*
9699/3-C69.0
ICD-O-3
Marginal zone B-cell lymphoma, NOS, of conjunctiva
+∞
11.5
11
*
C69.99
ICD-10 Finland
Malignant tumor in unspecified localization in eye or other unspecified histology
+∞
11.5
11
*
Z97.0
ICD-10 Finland
Presence of artificial eye
+∞
11.5
11
*
PC2ET
NOMESCO Finland
Extensive embolisation of lesion of liver
125.4
11.5
12
*
JN1DG
NOMESCO Finland
Very extensive MRI examination of upper part of abdomen with high intensity magnet
12.7
11.0
19
16
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
2.6
10.9
104
531
H02AB02
ATC
dexamethasone; systemic
3.9
10.8
46
135
CA1BG
NOMESCO Finland
Eye and orbita MRI examination with high intensity magnet
62.6
10.7
12
*
JN4BD
NOMESCO Finland
Extensive body CT
3.5
10.6
53
178
XX7GT
NOMESCO Finland
Selective internal radio therapy (SIRT) with Yttrium
+∞
10.5
10
*
CH2S4
NOMESCO Finland
Photography of iris
+∞
10.5
10
*
C69.60
ICD-10 Finland
Malignant tumor in orbit without histology
+∞
10.5
10
*
180
Kela drug reimbursment
Interferon alfa
27.2
9.9
13
5
S01ED01
ATC
timolol; ophthalmic
5.6
9.7
28
55
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
5.8
9.7
27
51
A04AA02
ATC
granisetron; systemic, transdermal
4.8
9.6
32
74
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
7.4
9.5
22
32
JN6AD
NOMESCO Finland
CT of torso and neck
22.7
9.4
13
6
H05.2
ICD-10 Finland
Exophthalmic conditions
+∞
9.4
9
*
C69.29
ICD-10 Finland
Retina
+∞
9.4
9
*
8720/3-C69.0
ICD-O-3
Malignant melanoma, NOS, of conjunctiva
+∞
9.4
9
*
N02AA05
ATC
oxycodone; systemic
2.9
9.3
63
260
JN4CD
NOMESCO Finland
Very extensive body CT
6.3
9.3
24
41
CA1ME
NOMESCO Finland
Ultrasound oculometry
16.3
9.1
14
9
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
4.0
9.0
36
100
Z3231
NOMESCO Finland
Registered nurse
2.4
9.0
95
503
CA1CM
NOMESCO Finland
Eye and orbita extensive MRI examination with 3 Tesla magnet
51.8
8.7
10
*
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
4.5
8.6
30
73
ZX070
NOMESCO Finland
Intensity modified radiotherapy
11.3
8.4
15
14
1905A
ICD-9 Finland
Malignant neoplasm of eye, Retina[RETINOBLASTOMA RETINAE]
+∞
8.4
8
*
C69.63
ICD-10 Finland
Malignant tumor of orbital carcinoma
+∞
8.4
8
*
19003
ICD-8 Finland
Malignant neoplasm of eye, Retinae
+∞
8.4
8
*
CAW99
NOMESCO Finland
Other operation on orbit
+∞
8.4
8
*
C69.2
ICD-10 Finland
Malignant neoplasm: Retina
+∞
8.4
8
*
XCD20
NOMESCO Finland
Photoangiography of eye
10.5
8.1
15
15
A06AH03
ATC
naloxegol; oral
34.5
8.1
10
*
CA1AE
NOMESCO Finland
Eye and orbita ultrasound examination
22.9
8.1
11
5
ZXA10
NOMESCO Finland
Bilateral
2.5
8.0
68
320
C82.1
ICD-10 Finland
Follicular lymphoma grade II
46.4
7.8
9
*
H33.0
ICD-10 Finland
Retinal detachment with retinal break
6.8
7.6
18
28
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.1
7.5
130
842
A04AA01
ATC
ondansetron; systemic, rectal
3.8
7.5
31
89
9591/3-C69.9
ICD-O-3
Malignant lymphoma, non-Hodgkin, NOS, of eye, NOS
+∞
7.3
7
*
Z85.8
ICD-10 Finland
Personal history of malignant neoplasms of other organs and systems
+∞
7.3
7
*
CAD00
NOMESCO Finland
Exenteration of orbit with use of graft or flap
+∞
7.3
7
*
C69.45
ICD-10 Finland
Melanoma of iris
+∞
7.3
7
*
ZX090
NOMESCO Finland
Other technic of radiotherapy
6.2
7.1
18
31
R1220
NOMESCO Finland
Psychological examination of need and possibilities to rehabilitation
17.2
6.8
10
6
R22.0
ICD-10 Finland
Localized swelling, mass and lump, head
6.2
6.7
17
29
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
6.0
6.6
17
30
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
5.3
6.3
18
36
C69.91
ICD-10 Finland
Malignant tumor in unspecified localization in the eye retinoblastoma
+∞
6.3
6
*
C69.90
ICD-10 Finland
Malignant tumor in unspecified localization in eye without histology
+∞
6.3
6
*
C85.9
ICD-10 Finland
Non-Hodgkin lymphoma, unspecified
27.4
6.3
8
*
L03AB05
ATC
interferon alfa-2b; parenteral
27.4
6.3
8
*
AA1CD
NOMESCO Finland
Very extensive CT of head and brain
8.0
6.2
13
17
WX408
NOMESCO Finland
General anesthesy, balanced
2.1
6.2
83
477
L03AA13
ATC
pegfilgrastim; parenteral
5.4
6.1
17
33
H43.1
ICD-10 Finland
Vitreous haemorrhage
6.3
6.1
15
25
EP1AE
NOMESCO Finland
Neck ultrasound examination
4.0
6.1
23
62
Z96.1
ICD-10 Finland
Presence of intraocular lens
2.4
6.0
52
244
Mortality – FinRegistry
↥This endpoint is excluded from FinRegistry analyses (omitted endpoint).
Relationships between endpoints
↥Index endpoint: C3_EYE_ADNEXA – Malignant neoplasm of eye and adnexa
GWS hits: -
This endpoint is excluded from FinRegistry analyses (omitted endpoint).