No definition available.
Malignant neoplasm of eye and adnexa, excluding all cancers (controls excluding all cancers)
C3_EYE_ADNEXA_EXALLC
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
3 out of 7 registries used, show all original rules. |
568 |
4. Check minimum number of eventsNone |
568 |
5. Include endpointsNone |
568 |
6. Filter based on genotype QC (FinnGen only) |
568 |
Control definitions (FinnGen only)
- Control exclude
- C3_CANCER, C3_CANCER_WIDE_EXALLC
Extra metadata
- First used in FinnGen datafreeze
- DF12
Similar endpoints
↥List of similar endpoints to
Malignant neoplasm of eye and adnexa, excluding all cancers (controls excluding all cancers)
based on the number of shared cases.
Similar with more cases:
- Malignant neoplasm of eye, brain and central nervous system, excluding all cancers (controls excluding all cancers)
- Malignant neoplasm, excluding all cancers (controls excluding all cancers)
- Malignant neoplasm, wide definition for exclusion
- Malignant neoplasm, wide definition for exclusion, excluding all cancers (controls excluding all cancers)
- Any event in hilmo or specialist outpatient
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded (different definition than used in FinnGen).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 568 | 260 | 308 |
| Unadjusted period prevalence (%) | 0.11 | 0.09 | 0.14 |
| Median age at first event (years) | 62.65 | 60.04 | 64.85 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 259
- Matched controls
- 2588
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
C69.30
ICD-10 Finland
Malignant tumor of the chorioidea without histology
+∞
155.3
133
*
CKE60
NOMESCO Finland
Brachytherapy of choroid and retina
+∞
137.0
119
*
CKE65
NOMESCO Finland
Removal of brachytherapeutic plate from eye
+∞
137.0
119
*
C69.32
ICD-10 Finland
Malignant tumor of the chorioidea melanoma
+∞
121.7
107
*
XCD10
NOMESCO Finland
Electrophysiological examination of eye
92.9
117.5
126
26
WX140
NOMESCO Finland
Parabulbar anesthesy
36.8
77.9
101
44
XCK10
NOMESCO Finland
Photography of fundus of eye
16.8
73.4
131
148
CK2L4
NOMESCO Finland
Wide-field/panoramic imaging of ocular fundus
201.9
73.3
73
5
C69.3
ICD-10 Finland
Malignant neoplasm: Choroid
+∞
71.2
65
*
8720/3-C69.9
ICD-O-3
Malignant melanoma, NOS, of eye, NOS
+∞
70.0
64
*
8720/3-C69.3
ICD-O-3
Malignant melanoma, NOS, of choroid
+∞
67.7
62
*
130
Kela drug reimbursment
Malignant tumour
+∞
59.7
55
*
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
17.9
55.3
91
76
C78.7
ICD-10 Finland
Secondary malignant neoplasm of liver and intrahepatic bile duct
+∞
46.2
43
*
H02AB02
ATC
dexamethasone; systemic
55.6
39.4
46
10
WX002
NOMESCO Finland
Sedation and analgesia
7.0
38.9
117
273
C69.39
ICD-10 Finland
Malignant tumor in chorioidea other or unspecified histology
+∞
37.4
35
*
CA1CG
NOMESCO Finland
Eye and orbita extensive MRI examination with high intensity magnet
114.2
36.9
39
*
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
+∞
36.3
34
*
WF002
NOMESCO Finland
Radical radiotherapy
398.1
35.9
35
*
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
8.8
34.9
82
129
A04AA02
ATC
granisetron; systemic, transdermal
366.7
32.6
32
*
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
+∞
31.9
30
*
C83.80
ICD-10 Finland
B-cell lymphoma in marginal zone
+∞
31.9
30
*
XCW99
NOMESCO Finland
Other investigative procedure of eye
7.0
30.8
86
172
A03FA01
ATC
metoclopramide; systemic, rectal
7.4
30.6
81
150
ZXA05
NOMESCO Finland
Left side
4.9
29.8
130
441
CFA20
NOMESCO Finland
Biopsy of conjunctiva
168.8
29.3
30
*
C69.02
ICD-10 Finland
Malignant tumor in conjunctival melanoma
+∞
28.7
27
*
9510/3-C69.2
ICD-O-3
Retinoblastoma, NOS, of retina
+∞
27.6
26
*
CAA30
NOMESCO Finland
Biopsy of orbit
+∞
26.5
25
*
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
50.0
26.2
31
7
JN4BD
NOMESCO Finland
Extensive body CT
10.3
25.9
53
63
Z51.5
ICD-10 Finland
Palliative care
16.0
25.1
41
30
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
8.8
24.5
55
77
C69.00
ICD-10 Finland
Malignant tumor of the conjunctiva without histology
+∞
24.3
23
*
Z01.0
ICD-10 Finland
Examination of eyes and vision
4.8
23.4
91
260
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
+∞
23.3
22
*
YA1BD
NOMESCO Finland
Extensive CT examination of head and neck for dose design of radiotherapy
+∞
23.3
22
*
CF2S4
NOMESCO Finland
Photography of conjunctiva
239.3
21.9
22
*
1906B
ICD-9 Finland
Malignant neoplasm of eye, Choroid[MELANOMA CHORIOIDEAE]
+∞
21.1
20
*
ZXA00
NOMESCO Finland
Right side
3.8
20.9
122
496
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
4.0
20.7
104
373
8140/3-C61.9
ICD-O-3
Adenocarcinoma, NOS, of prostate gland
+∞
20.1
19
*
D31.3
ICD-10 Finland
Benign neoplasm: Choroid
21.6
20.0
29
15
ZX090
NOMESCO Finland
Other technic of radiotherapy
+∞
19.0
18
*
A04AA01
ATC
ondansetron; systemic, rectal
15.1
18.8
31
23
C61
ICD-10 Finland
Malignant neoplasm of prostate
204.1
18.8
19
*
S01ED51
ATC
timolol, combinations; ophthalmic
6.1
18.7
54
107
CA1DG
NOMESCO Finland
Eye and orbita very extensive MRI examination with high intensity magnet
+∞
17.9
17
*
L03AA13
ATC
pegfilgrastim; parenteral
+∞
17.9
17
*
H40.5
ICD-10 Finland
Glaucoma secondary to other eye disorders
45.5
17.6
21
5
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
13.4
17.3
30
25
CFC00
NOMESCO Finland
Excision of lesion of conjunctiva
53.9
17.2
20
*
L01AX03
ATC
temozolomide; systemic
+∞
16.8
16
*
WF003
NOMESCO Finland
Adjuvant radiotherapy
+∞
16.8
16
*
C69.21
ICD-10 Finland
Retina
+∞
16.8
16
*
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
181.1
16.7
17
*
N02AA05
ATC
oxycodone; systemic
4.6
16.5
63
170
XW000
NOMESCO Finland
Bone marrow biopsy
11.2
16.5
31
31
CKD05
NOMESCO Finland
Puncture of vitreous body with injection of medication
7.0
16.1
41
68
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
14.2
16.1
27
21
3770
FHL
Placing a radiating plate on the surface of the eye with additional measures
+∞
15.8
15
*
9699/3-C69.6
ICD-O-3
Marginal zone B-cell lymphoma, NOS, of orbit, NOS
+∞
15.8
15
*
ZX070
NOMESCO Finland
Intensity modified radiotherapy
+∞
15.8
15
*
8000/3-C69.3
ICD-O-3
Neoplasm, malignant of choroid
+∞
15.8
15
*
WD405
NOMESCO Finland
Simple antiboidy therapy of methastized malignancy
+∞
15.8
15
*
C69.40
ICD-10 Finland
Malignant tumor of ciliary body without histology
+∞
15.8
15
*
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
3.0
15.7
141
740
JN4CD
NOMESCO Finland
Very extensive body CT
17.5
15.6
24
15
C69.42
ICD-10 Finland
Malignant tumor of ciliary melanoma
+∞
14.7
14
*
3779
FHL
Other operations in this group include disc removal
+∞
14.7
14
*
CDC10
NOMESCO Finland
Enucleation of eye with insertion of prosthesis
+∞
14.7
14
*
Z90.0
ICD-10 Finland
Acquired absence of part of head and neck
158.5
14.6
15
*
D31.6
ICD-10 Finland
Benign neoplasm: Orbit, unspecified
158.5
14.6
15
*
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
18.3
14.6
22
13
XX3DW
NOMESCO Finland
Time consuming IT work
7.2
14.3
35
55
CBA10
NOMESCO Finland
Biopsy of eyelid
45.2
14.3
17
*
CDC00
NOMESCO Finland
Enucleation of eye
+∞
13.7
13
*
115
Kela drug reimbursment
Breast cancer
+∞
13.7
13
*
WF049
NOMESCO Finland
Radiotherapy of metastasis
+∞
13.7
13
*
180
Kela drug reimbursment
Interferon alfa
+∞
13.7
13
*
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
19.6
13.6
20
11
JN1DG
NOMESCO Finland
Very extensive MRI examination of upper part of abdomen with high intensity magnet
22.6
13.5
19
9
D31.0
ICD-10 Finland
Benign neoplasm: Conjunctiva
20.4
13.1
19
10
WX408
NOMESCO Finland
General anesthesy, balanced
3.2
13.0
83
336
CD2S4
NOMESCO Finland
Photography of eye
73.5
12.7
14
*
C69.20
ICD-10 Finland
Retina
+∞
12.6
12
*
PC2ET
NOMESCO Finland
Extensive embolisation of lesion of liver
+∞
12.6
12
*
WD415
NOMESCO Finland
Demanding antibody therapy of methastized malignancy
+∞
12.6
12
*
C69.09
ICD-10 Finland
Malignant tumor in conjunctival other or unspecified histology
+∞
12.6
12
*
HAC20
NOMESCO Finland
Total mastectomy
+∞
12.6
12
*
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
2.6
12.3
126
683
JN6AD
NOMESCO Finland
CT of torso and neck
68.1
11.7
13
*
S01ED01
ATC
timolol; ophthalmic
7.2
11.6
28
43
YX9AD
NOMESCO Finland
Other CT eamination for dose design of radiotherapy
+∞
11.5
11
*
C69.99
ICD-10 Finland
Malignant tumor in unspecified localization in eye or other unspecified histology
+∞
11.5
11
*
9699/3-C69.0
ICD-O-3
Marginal zone B-cell lymphoma, NOS, of conjunctiva
+∞
11.5
11
*
C69.03
ICD-10 Finland
Malignant tumor of conjunctival carcinoma
+∞
11.5
11
*
C83.31
ICD-10 Finland
Diffuse lymphoma with large B cells
+∞
11.5
11
*
PJA12
NOMESCO Finland
Sentinel node biopsy
+∞
11.5
11
*
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
8.7
11.4
24
30
CA1ME
NOMESCO Finland
Ultrasound oculometry
29.4
10.8
14
5
WF004
NOMESCO Finland
Palliative radiotherapy
+∞
10.5
10
*
CH2S4
NOMESCO Finland
Photography of iris
+∞
10.5
10
*
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
+∞
10.5
10
*
XX7GT
NOMESCO Finland
Selective internal radio therapy (SIRT) with Yttrium
+∞
10.5
10
*
116
Kela drug reimbursment
Prostate cancer
+∞
10.5
10
*
C69.60
ICD-10 Finland
Malignant tumor in orbit without histology
+∞
10.5
10
*
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
4.6
10.4
36
87
WX142
NOMESCO Finland
Sub-tenon anesthesy
24.5
10.3
14
6
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.4
10.2
130
766
R22.0
ICD-10 Finland
Localized swelling, mass and lump, head
12.9
10.0
17
14
Z97.0
ICD-10 Finland
Presence of artificial eye
57.2
9.7
11
*
H26.2
ICD-10 Finland
Complicated cataract
10.6
9.7
18
18
A06AH03
ATC
naloxegol; oral
103.6
9.5
10
*
ZX080
NOMESCO Finland
Image guided radiotherapy
+∞
9.4
9
*
C82.1
ICD-10 Finland
Follicular lymphoma grade II
+∞
9.4
9
*
C69.29
ICD-10 Finland
Retina
+∞
9.4
9
*
8720/3-C69.0
ICD-O-3
Malignant melanoma, NOS, of conjunctiva
+∞
9.4
9
*
XZZ00
NOMESCO Finland
Active surveillance of a diagnosed cancer
+∞
9.4
9
*
JN4AD
NOMESCO Finland
Body CT examination
6.5
9.2
23
38
AA1CD
NOMESCO Finland
Very extensive CT of head and brain
19.5
9.0
13
7
WZC30
NOMESCO Finland
Teaching
3.7
8.9
39
118
CA1CM
NOMESCO Finland
Eye and orbita extensive MRI examination with 3 Tesla magnet
51.8
8.7
10
*
L02AE02
ATC
leuprorelin; implant, parenteral
51.8
8.7
10
*
R1220
NOMESCO Finland
Psychological examination of need and possibilities to rehabilitation
51.8
8.7
10
*
CA1AE
NOMESCO Finland
Eye and orbita ultrasound examination
28.6
8.5
11
*
CA1BG
NOMESCO Finland
Eye and orbita MRI examination with high intensity magnet
20.9
8.5
12
6
C69.63
ICD-10 Finland
Malignant tumor of orbital carcinoma
+∞
8.4
8
*
C85.9
ICD-10 Finland
Non-Hodgkin lymphoma, unspecified
+∞
8.4
8
*
C50.41
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, ductal tumor
+∞
8.4
8
*
19003
ICD-8 Finland
Malignant neoplasm of eye, Retinae
+∞
8.4
8
*
A04AA55
ATC
palonosetron, combinations; systemic
+∞
8.4
8
*
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
+∞
8.4
8
*
YG1BD
NOMESCO Finland
Extensive CT examination of thorax for dose design of radiotherapy
+∞
8.4
8
*
CAW99
NOMESCO Finland
Other operation on orbit
+∞
8.4
8
*
WB113
NOMESCO Finland
Multiple adjuvant cytostatic therapy
+∞
8.4
8
*
L02BB03
ATC
bicalutamide; oral
+∞
8.4
8
*
C69.2
ICD-10 Finland
Malignant neoplasm: Retina
+∞
8.4
8
*
1905A
ICD-9 Finland
Malignant neoplasm of eye, Retina[RETINOBLASTOMA RETINAE]
+∞
8.4
8
*
L03AA14
ATC
lipegfilgrastim; parenteral
+∞
8.4
8
*
PJD52
NOMESCO Finland
Block dissection of axillary lymph nodes
+∞
8.4
8
*
ZXA10
NOMESCO Finland
Bilateral
2.6
8.1
68
316
EP1AE
NOMESCO Finland
Neck ultrasound examination
5.4
7.9
23
46
H33.0
ICD-10 Finland
Retinal detachment with retinal break
7.4
7.9
18
26
H05.2
ICD-10 Finland
Exophthalmic conditions
46.4
7.8
9
*
ZX120
NOMESCO Finland
Intravenous
4.1
7.6
29
78
L03AB05
ATC
interferon alfa-2b; parenteral
82.3
7.5
8
*
WD115
NOMESCO Finland
Multiple cystostatic therapy of methastized malignancy
82.3
7.5
8
*
HAB40
NOMESCO Finland
Wedge excision of mammary gland
82.3
7.5
8
*
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
+∞
7.3
7
*
C79.5
ICD-10 Finland
Secondary malignant neoplasm of bone and bone marrow
+∞
7.3
7
*
C69.45
ICD-10 Finland
Melanoma of iris
+∞
7.3
7
*
WD325
NOMESCO Finland
Demanding therapy of methastized malignancy with biomodifiers
+∞
7.3
7
*
9591/3-C69.9
ICD-O-3
Malignant lymphoma, non-Hodgkin, NOS, of eye, NOS
+∞
7.3
7
*
CAD00
NOMESCO Finland
Exenteration of orbit with use of graft or flap
+∞
7.3
7
*
166
Kela drug reimbursment
Dalteparin and tinzaparin (treatment for more than 6 months)
+∞
7.3
7
*
Z85.8
ICD-10 Finland
Personal history of malignant neoplasms of other organs and systems
+∞
7.3
7
*
3102
FHL
Enucleation
+∞
7.3
7
*
YA1VG
NOMESCO Finland
MRI examination of head and neck with high intesity magnet for dose design of radiotherapy
+∞
7.3
7
*
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
6.4
7.2
18
30
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.9
7.1
44
170
EN1BD
NOMESCO Finland
Very extensive CT examination of mouth and soft tissues of neck
11.4
6.9
12
11
Z96.1
ICD-10 Finland
Presence of intraocular lens
2.6
6.8
52
228
HA1AA
NOMESCO Finland
X-ray mammography
7.5
6.8
15
21
CA1AD
NOMESCO Finland
Orbita CT
41.1
6.8
8
*
YA1AD
NOMESCO Finland
CT examination of head and neck for dose design of radiotherapy
41.1
6.8
8
*
QAB10
NOMESCO Finland
Major dressing of wound of skin of head or neck
41.1
6.8
8
*
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
6.2
6.7
17
29
D48.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other specified sites
23.2
6.7
9
*
ZX112
NOMESCO Finland
Subcutaneous
23.2
6.7
9
*
XCD20
NOMESCO Finland
Photoangiography of eye
7.2
6.6
15
22
H43.1
ICD-10 Finland
Vitreous haemorrhage
7.2
6.6
15
22
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
6.5
6.6
16
26
Z51.1
ICD-10 Finland
Chemotherapy session for neoplasm
71.5
6.5
7
*
C69.90
ICD-10 Finland
Malignant tumor in unspecified localization in eye without histology
+∞
6.3
6
*
C83.1
ICD-10 Finland
Mantle cell lymphoma
+∞
6.3
6
*
C69.91
ICD-10 Finland
Malignant tumor in unspecified localization in the eye retinoblastoma
+∞
6.3
6
*
L03AA02
ATC
filgrastim; parenteral
+∞
6.3
6
*
C64.88
ICD-10 Finland
Other malignant neoplasm of kidney, except renal pelvis
+∞
6.3
6
*
CAB00
NOMESCO Finland
Anterior orbitotomy with excision of lesion
+∞
6.3
6
*
CFD10
NOMESCO Finland
Repair of conjunctiva
+∞
6.3
6
*
A04AD12
ATC
aprepitant; systemic
+∞
6.3
6
*
C78.0
ICD-10 Finland
Secondary malignant neoplasm of lung
+∞
6.3
6
*
8090/3-C44.3
ICD-O-3
Basal cell carcinoma, NOS, of skin of other and unspecified parts of face
+∞
6.3
6
*
C85.1
ICD-10 Finland
B-cell lymphoma, unspecified
+∞
6.3
6
*
PC2DT
NOMESCO Finland
Embolisation of lesion of liver
+∞
6.3
6
*
L02BG04
ATC
letrozole; oral
27.4
6.3
8
*
WW500
NOMESCO Finland
Blood transfusion
8.9
6.1
12
14
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
309
1271
4.14
61.82
5.3
2.8
30.9
33.3
u/l
0.69
299
1207
339
2045
2.63
27.57
10.7
3.9
12.6
12.1
umol/l
0.22
331
1925
83
237
3.93
25.82
3.4
1.4
7.5
4.1
ug/l
0.51
62
186
450
3209
2.94
24.79
13.8
5.4
86.4
77.3
u/l
2.26
429
2943
349
2269
2.40
22.19
15.7
6.3
3.9
4.3
e9/l
2.59
312
1974
26
6
45.25
21.58
1.3
1.8
—
—
—
0
0
44
89
5.27
21.00
2.2
1.7
19.2
147.8
u/ml
0.75
37
68
18
0
+∞
18.85
1.1
0.0
—
—
—
0
0
32
57
5.89
17.45
1.2
1.2
—
—
—
0
0
286
1828
2.14
17.40
6.5
3.9
34.7
35.4
g/l
1.33
264
1668
320
2166
2.09
16.37
9.2
6.0
1.2
1.2
mmol/l
0.55
265
1847
19
22
8.90
15.09
2.5
1.7
710.0
1016.2
e6/l
—
9
9
128
627
2.34
14.72
4.1
3.3
0.8
0.8
mmol/l
0.61
123
575
14
0
+∞
14.64
1.1
0.0
35.6
—
%
—
14
0
14
0
+∞
14.64
1.0
0.0
8.9
—
%
—
14
0
25
42
6.18
14.43
2.3
1.6
7.2
90.8
u/ml
0.46
25
42
290
1953
1.99
14.39
8.2
5.6
1.2
1.2
mmol/l
0.24
273
1727
79
338
2.55
12.08
2.7
2.0
0.2
0.2
g/l
0.39
73
308
212
1402
1.82
10.13
6.8
2.1
2.3
2.4
mmol/l
0.22
187
1150
342
2623
1.76
9.64
6.5
4.5
6.8
6.9
mmol/l
0.31
326
2440
259
1841
1.75
9.52
4.6
3.7
—
—
—
0
0
153
929
1.89
9.51
3.2
2.1
—
—
—
0
0
11
13
8.61
8.49
1.1
1.1
—
—
—
0
0
24
68
3.64
7.50
4.0
3.1
53.8
58.4
%
0.69
24
68
14
26
5.50
7.28
2.1
1.3
21.7
15.3
ug/l
0.99
14
26
11
7
15.98
7.25
5.5
1.0
23.6
13.7
u/ml
—
11
7
192
1340
1.65
7.04
3.4
2.3
61.1
56.1
u/l
0.77
179
1242
23
67
3.54
6.91
3.3
2.8
4.0
4.6
e9/l
0.42
23
67
12
21
5.82
6.61
1.2
1.2
—
—
—
0
0
79
435
1.95
6.44
4.2
2.4
10.7
8.3
umol/l
0.32
64
371
34
138
2.56
5.81
1.9
3.3
—
—
—
0
0
167
1183
1.58
5.54
3.5
3.0
0.5
0.4
e6/l
0.10
130
887
93
566
1.77
5.52
3.0
2.5
21.8
24.0
%
0.90
81
479
5
0
+∞
5.21
2.4
0.0
0.1
—
ug/l
—
5
0
207
1557
1.52
5.19
4.0
3.1
—
—
—
0
0
9
9
10.14
5.04
2.2
1.1
—
—
—
0
0
90
563
1.71
4.84
7.3
5.5
1.1
1.0
mmol/l
0.89
79
511
64
363
1.86
4.78
4.5
1.6
64.9
67.0
g/l
1.17
59
322
121
820
1.60
4.77
5.2
2.2
2.5
2.4
mmol/l
0.89
106
695
95
609
1.67
4.66
3.0
2.4
2.3
2.3
g/l
0.03
90
563
161
1172
1.52
4.62
3.2
2.5
6286.9
7594.7
umol/l
0.11
141
989
73
444
1.74
4.33
3.4
3.2
—
—
—
0
0
30
135
2.29
4.16
2.7
1.3
0.5
0.4
g/l
0.16
25
116
100
673
1.59
4.03
2.8
2.9
1.2
2.6
e6/l
1.35
54
364
473
4316
1.57
3.95
23.3
13.5
24.7
24.3
mg/l
0.10
406
3367
33
160
2.13
3.85
1.5
1.4
3.1
3.1
g/l
0.04
27
120
20
77
2.66
3.84
1.4
1.4
—
—
—
0
0
105
727
1.55
3.73
2.0
1.8
—
—
—
0
0
58
348
1.74
3.63
2.1
2.0
34.8
31.7
u/l
0.13
48
283
34
173
2.03
3.51
1.5
1.3
7.7
7.6
g/l
0.13
29
123
34
173
2.03
3.51
1.5
1.3
—
—
—
0
0
24
106
2.32
3.50
1.5
1.6
—
—
—
0
0
9
18
5.06
3.38
4.2
1.3
259.8
214.7
u/l
—
9
18
16
59
2.76
3.35
1.3
1.5
92.8
112.7
u/ml
—
5
9
23
102
2.31
3.33
2.5
2.1
12.9
11.9
mg/l
0.31
23
97
17
65
2.67
3.33
1.2
1.4
—
—
—
0
0
33
173
1.96
3.16
1.5
1.3
3.5
3.9
g/l
1.34
27
118
16
61
2.67
3.16
1.2
1.5
248.1
271.3
u/ml
—
9
36
9
20
4.55
3.12
1.3
2.5
9.1
3.7
nmol/l
—
9
20
11
34
3.28
3.07
1.3
1.5
—
—
—
0
0
15
57
2.68
2.98
1.2
1.3
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
26
130
2.05
2.85
2.8
6.2
0.3
0.3
u/ml
0.07
13
76
11
36
3.10
2.82
1.5
1.3
—
—
—
0
0
8
18
4.49
2.80
2.6
1.9
—
—
—
0
0
248
2093
1.33
2.79
3.9
3.8
0.0
0.0
estimate
0.00
50
339
95
685
1.46
2.77
3.0
2.4
12.5
13.5
umol/l
0.62
89
628
5
6
8.39
2.75
1.0
1.0
—
—
—
0
0
5
6
8.39
2.75
1.0
1.0
—
—
—
0
0
15
60
2.54
2.72
1.7
1.6
—
—
—
0
0
99
723
1.45
2.71
2.8
2.7
1.2
1.1
e6/l
0.06
54
414
45
278
1.67
2.58
2.3
1.6
—
—
—
0
0
12
44
2.76
2.56
1.2
1.0
—
—
—
0
0
115
872
1.40
2.55
2.0
1.9
1.3
1.2
mg/l
0.29
94
676
5
7
7.19
2.55
1.2
1.1
—
—
—
0
0
34
195
1.79
2.53
2.0
1.7
1.5
1.6
g/l
0.17
27
171
22
109
2.06
2.49
2.8
1.7
—
—
—
0
0
74
519
1.49
2.49
1.7
1.8
—
—
—
0
0
19
89
2.17
2.47
1.4
1.2
—
—
—
0
0
19
89
2.17
2.47
1.4
1.2
—
—
—
0
0
73
513
1.49
2.43
8.1
7.1
0.7
1.5
mmol/l
1.03
56
391
6
12
5.04
2.40
1.2
1.0
1420.0
1871.1
miu/ml
—
6
12
73
515
1.48
2.39
8.2
7.0
5.1
5.1
kpa
0.05
68
490
384
4164
0.76
2.38
6.3
6.5
40.3
40.8
mmol/mol
0.38
360
3820
8
22
3.67
2.37
1.9
3.4
—
—
—
0
0
24
126
1.94
2.34
3.7
1.3
57.1
45.1
mg/l
0.25
17
102
24
126
1.94
2.34
3.7
1.3
23.4
32.6
mg/l
1.55
17
102
73
518
1.47
2.32
1.8
1.8
—
—
—
0
0
66
459
1.50
2.32
5.8
3.3
1.8
2.0
mmol/l
0.24
53
363
416
4457
0.75
2.31
5.0
5.3
2.7
2.7
mmol/l
0.02
390
4062
5
9
5.59
2.21
1.2
1.2
—
—
—
0
0
401
4309
0.76
2.19
4.4
4.7
1.4
1.4
mmol/l
0.35
376
3919
489
4624
1.41
2.16
17.3
9.1
27.4
25.3
u/l
2.06
474
4423
65
460
1.47
2.11
5.8
3.3
5.6
5.8
kpa
0.58
65
445
17
82
2.11
2.09
1.7
1.6
—
—
—
0
0
42
273
1.58
2.01
1.5
1.6
—
—
—
0
0
9
32
2.84
2.01
1.0
1.0
—
—
—
0
0
356
3244
1.26
1.92
4.8
4.1
14.0
12.4
mm/h
1.07
332
2949
408
4350
0.78
1.89
4.5
4.7
4.5
4.5
mmol/l
0.04
381
3984
9
34
2.67
1.87
1.7
1.3
—
—
—
0
0
5
12
4.19
1.82
1.0
1.1
—
—
—
0
0
54
382
1.46
1.78
6.0
3.0
4.8
4.5
kpa
0.35
54
367
241
2115
1.24
1.77
4.0
3.8
0.0
0.0
estimate
0.50
51
332
10
41
2.46
1.76
2.8
2.1
—
—
—
0
0
297
2668
1.24
1.76
4.2
3.0
75.1
48.0
u/l
2.28
279
2462
238
2088
1.24
1.75
5.0
5.2
0.0
0.0
estimate
0.00
49
337
213
1848
1.24
1.73
4.1
3.9
30.6
79.2
ng/l
1.11
160
1364
16
82
1.98
1.71
1.1
1.7
—
—
—
0
0
12
55
2.21
1.68
1.7
1.6
—
—
—
0
0
33
213
1.58
1.66
7.0
5.7
25.7
24.8
mmol/l
0.58
33
197
22
128
1.75
1.62
1.5
1.3
—
—
—
0
0
116
946
1.28
1.58
4.6
4.1
334.1
362.7
ng/l
0.04
98
778
135
1126
1.26
1.53
4.2
4.0
0.0
0.0
estimate
0.50
45
334
392
4166
0.81
1.52
4.0
4.2
1.4
1.3
mmol/l
1.40
368
3758
10
45
2.24
1.47
1.4
1.8
—
—
—
0
0
98
1199
0.78
1.45
1.8
1.7
1.4
1.4
mmol/l
0.19
90
993
7
28
2.52
1.45
1.4
1.2
20.0
33.3
u/l
—
7
21
16
88
1.84
1.43
1.7
1.5
—
—
—
0
0
17
287
0.58
1.42
1.5
1.8
—
—
—
0
0
9
40
2.27
1.40
1.1
1.1
—
—
—
0
0
43
308
1.43
1.37
6.0
5.0
2.2
1.8
mmol/l
0.23
35
227
37
261
1.45
1.28
1.6
1.4
—
—
—
0
0
5
19
2.65
1.22
1.6
1.2
—
—
—
0
0
172
1512
1.20
1.17
3.5
3.2
1327.7
1632.1
ng/l
0.86
154
1279
51
390
1.34
1.13
1.7
1.8
1.9
1.6
%
0.72
43
334
52
667
0.76
1.12
1.3
1.2
31.9
10.1
u/ml
0.65
17
247
26
177
1.49
1.10
2.1
1.6
—
—
—
0
0
15
89
1.70
1.08
1.2
1.3
—
—
—
0
0
12
67
1.81
1.05
1.4
1.4
—
—
—
0
0
56
440
1.30
1.04
2.6
3.9
333.7
235.1
ng/l
0.66
50
409
417
4353
0.84
1.02
4.8
4.8
6.0
6.1
mmol/l
0.25
383
3917
371
3502
1.17
1.02
27.6
16.0
14.1
13.7
%
4.65
365
3406
35
257
1.39
1.01
2.0
2.8
24.5
25.3
mmol/l
0.73
35
250
24
165
1.47
0.98
1.8
1.5
—
—
—
0
0
5
23
2.18
0.98
1.0
1.4
—
—
—
0
0
5
23
2.18
0.98
4.2
1.7
—
—
—
0
0
5
23
2.18
0.98
4.2
1.7
—
—
—
0
0
46
356
1.32
0.97
2.7
2.2
48.8
61.9
ml/min/173m2
1.58
16
151
81
678
1.23
0.92
25.7
27.2
1.3
1.3
inr
0.01
11
94
14
86
1.64
0.91
1.5
1.7
1.7
4.6
iu/l
—
6
31
57
695
0.80
0.85
1.3
1.3
44.3
36.0
iu/ml
0.24
21
221
6
31
1.95
0.84
2.0
1.1
—
—
—
0
0
6
31
1.95
0.84
2.0
1.1
—
—
—
0
0
6
31
1.95
0.84
2.0
1.1
—
—
—
0
0
11
65
1.71
0.83
1.2
1.1
—
—
—
0
0
92
1061
0.84
0.79
1.7
1.7
534.2
21810176.1
pmol/l
1.00
78
862
6
34
1.77
0.76
1.7
1.6
—
—
—
0
0
9
55
1.65
0.73
1.6
1.3
—
—
—
0
0
16
110
1.47
0.69
3.6
3.7
42.6
27.0
mg/l
—
10
77
5
27
1.86
0.68
1.0
1.0
—
—
—
0
0
5
27
1.86
0.68
1.0
1.0
—
—
—
0
0
471
4581
1.16
0.68
26.0
16.5
139.5
139.7
mmol/l
0.88
457
4442
193
1782
1.13
0.66
2.4
2.3
80.4
77.8
nmol/l
0.57
176
1562
472
4596
1.16
0.65
26.0
16.6
4.0
4.0
mmol/l
0.10
455
4448
11
71
1.56
0.62
1.4
1.5
—
—
—
0
0
8
49
1.64
0.62
1.5
1.3
—
—
—
0
0
8
50
1.61
0.61
1.0
1.2
—
—
—
0
0
9
138
0.65
0.61
1.6
1.3
—
—
—
0
0
8
51
1.58
0.60
1.0
1.2
—
—
—
0
0
8
51
1.58
0.60
1.0
1.2
—
—
—
0
0
8
52
1.55
0.59
1.0
1.2
—
—
—
0
0
8
52
1.55
0.59
1.0
1.2
—
—
—
0
0
8
52
1.55
0.59
1.0
1.2
—
—
—
0
0
14
97
1.45
0.59
1.3
2.1
—
—
—
0
0
126
1144
1.13
0.57
2.2
2.2
3.0
3.0
mg/l
0.06
115
963
186
1992
0.90
0.54
2.3
2.1
93.6
94.3
pmol/l
0.07
102
1002
146
1580
0.90
0.51
4.4
4.0
17.9
7.6
mg/mmol
1.37
103
1002
13
92
1.42
0.51
1.2
1.3
—
—
—
0
0
416
4041
1.11
0.50
21.6
12.2
76.3
75.6
ml/min/173m2
0.25
362
3232
6
41
1.47
0.50
1.8
1.5
—
—
—
0
0
10
143
0.69
0.48
2.4
2.3
849.8
70.3
ug/min
—
5
87
63
553
1.16
0.47
1.3
1.5
—
—
—
0
0
7
49
1.43
0.46
1.1
1.1
—
—
—
0
0
7
50
1.40
0.45
2.0
3.8
—
—
—
0
0
8
56
1.43
0.42
1.5
1.3
—
—
—
0
0
391
4014
0.92
0.41
5.4
4.5
1.9
2.0
mu/l
1.34
362
3602
0
15
0.00
0.41
0.0
1.2
—
9.4
—
0
15
490
4818
1.12
0.41
33.3
19.8
132.2
135.7
g/l
5.08
480
4723
8
60
1.34
0.40
1.3
1.5
0.5
0.6
nmol/l
—
8
53
12
88
1.37
0.40
1.0
1.2
—
—
—
0
0
172
1622
1.09
0.38
4.2
4.0
—
—
—
0
0
145
1544
0.92
0.37
3.6
3.2
7.3
7.5
mmol/l
0.15
119
1293
135
1437
0.92
0.34
5.0
3.7
23.4
24.4
%
0.28
76
670
338
3284
1.07
0.33
4.5
3.7
15.0
15.0
pmol/l
0.06
314
2940
49
436
1.14
0.33
1.3
1.4
—
—
—
0
0
15
186
0.80
0.31
1.7
1.3
—
—
—
0
0
7
55
1.28
0.30
1.0
1.1
—
—
—
0
0
54
488
1.12
0.29
2.3
2.4
5.4
6.9
ug/l
0.53
44
421
11
137
0.80
0.24
1.1
2.2
—
—
—
0
0
26
228
1.15
0.23
1.2
1.2
140.3
133.1
iu/ml
0.04
11
94
5
41
1.22
0.22
1.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.4
—
—
—
0
0
0
12
0.00
0.21
0.0
2.4
—
1.2
—
0
12
0
12
0.00
0.21
0.0
1.8
—
—
—
0
0
390
3838
1.05
0.20
24.0
14.7
38.3
39.7
%
1.79
264
2545
56
597
0.93
0.17
13.4
7.4
—
—
—
0
0
151
1460
1.05
0.16
2.6
2.1
190.6
212.1
u/l
0.16
140
1359
90
859
1.06
0.16
1.3
1.3
0.5
1.9
u/ml
2.72
15
227
7
87
0.80
0.14
1.4
1.4
—
—
—
0
0
11
128
0.86
0.13
1.7
1.2
—
—
—
0
0
11
128
0.86
0.13
1.7
1.2
—
—
—
0
0
21
230
0.91
0.11
1.5
1.9
—
—
—
0
0
11
95
1.16
0.11
1.5
1.3
—
—
—
0
0
114
1173
0.96
0.10
1.8
1.5
20.6
21.0
nmol/l
0.09
104
992
5
45
1.11
0.10
1.4
1.6
—
—
—
0
0
30
281
1.07
0.09
1.7
2.3
10.0
15.0
nmol/l
2.40
25
248
5
48
1.04
0.09
1.2
1.4
—
—
—
0
0
11
123
0.89
0.08
1.7
1.7
—
—
—
0
0
19
205
0.92
0.08
1.4
1.8
—
—
—
0
0
8
78
1.03
0.07
1.5
1.6
353.8
265.4
mu/l
—
8
69
180
1773
1.02
0.07
5.4
3.9
3.4
2.0
ug/l
0.63
160
1573
7
83
0.84
0.07
1.0
1.1
29.5
21.7
u/l
—
7
71
102
997
1.03
0.07
1.9
1.8
1229.4
1174.0
nmol/l
0.26
85
739
17
158
1.08
0.06
6.9
4.2
4.0
3.9
mmol/l
0.19
17
147
11
100
1.10
0.05
1.3
1.1
—
—
—
0
0
179
1775
1.01
0.03
3.2
2.7
179.4
134.4
ug/l
1.19
170
1607
18
188
0.96
0.02
6.9
3.7
1.2
1.5
mmol/l
1.01
18
182
59
597
0.99
0.01
4.7
5.0
32.2
32.3
%
0.01
45
389
17
164
1.04
0.00
1.1
1.0
—
—
—
0
0
99
985
1.01
0.00
3.3
2.6
0.8
0.8
ug/l
0.01
74
659
100
996
1.00
0.00
4.7
4.1
1.0
1.0
kg/l
0.32
15
161
234
2335
1.00
0.00
2.5
2.6
—
—
—
0
0
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
9
99
0.91
0.00
1.2
1.2
—
—
—
0
0
6
63
0.95
0.00
3.0
4.0
240.2
355.4
umol/l
—
6
55
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
2.0
—
—
—
0
0
9
94
0.96
0.00
1.1
1.2
—
2.5
—
0
8
8
80
1.00
0.00
1.3
2.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
23.1
—
0
6
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥This endpoint is excluded (different definition than used in FinnGen).
Relationships between endpoints
↥Index endpoint: C3_EYE_ADNEXA_EXALLC – Malignant neoplasm of eye and adnexa, excluding all cancers (controls excluding all cancers)
GWS hits: 1
This endpoint is excluded (different definition than used in FinnGen).