info icon

Any event in hilmo or specialist outpatient

ANY_HILMO

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 ANY
  • Hospital discharge: ICD-9 ANY
  • Hospital discharge: ICD-8 ANY

1 out of 7 registries used, show all original rules.

516428

4. Check minimum number of events

None

516428

5. Include endpoints

None

516428

6. Filter based on genotype QC (FinnGen only)

516428

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

No data for upset plot.

No data for upset table.

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 516428 292086 224342
Unadjusted period prevalence (%) 99.27 99.56 98.90
Median age at first event (years) 25.90 22.65 30.13

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

No data available

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
225
56
31.75
206.16
5.1
1.9
—
—
—
0
0
294
200
13.10
177.61
6.3
2.4
6.5
6.9
mmol/l
1.06
273
170
379
408
9.92
168.23
7.5
1.5
77.8
71.9
u/l
0.94
360
372
173
46
26.81
153.16
8.5
2.9
1.1
1.1
inr
0.02
51
17
150
21
49.09
152.88
2.7
1.4
—
—
—
0
0
243
151
12.89
152.13
6.9
1.4
10.9
12.7
umol/l
0.94
235
142
310
319
8.72
138.06
9.2
1.9
4.1
3.7
e9/l
1.66
276
283
177
74
17.06
132.90
8.9
2.1
1.2
1.2
mmol/l
0.09
167
64
170
71
16.86
127.42
1.6
1.2
—
—
—
0
0
554
1180
8.77
126.68
12.7
2.1
23.1
21.4
mg/l
0.40
422
663
189
104
13.16
124.39
10.9
2.0
1.2
1.2
mmol/l
1.12
167
96
372
541
6.89
120.89
3.6
1.6
8.2
6.7
mm/h
1.70
349
493
121
19
41.56
119.89
5.5
2.4
—
—
—
0
0
153
63
16.59
114.77
2.4
1.3
23.4
10.5
e6/l
0.68
124
42
294
361
6.93
109.63
4.0
1.4
85.9
1583.6
e6/l
—
10
5
176
106
11.71
109.49
6.0
1.5
36.4
39.7
g/l
5.31
170
99
521
1144
6.95
109.39
14.8
2.4
139.6
140.2
mmol/l
6.64
503
1069
524
1168
6.91
107.72
14.9
2.5
4.0
4.0
mmol/l
2.93
505
1094
175
109
11.29
106.64
3.1
1.4
51.0
299.0
e6/l
0.63
129
62
338
501
6.19
104.99
4.1
1.5
—
—
—
0
0
155
81
13.06
103.68
6.2
2.4
—
—
—
0
0
256
284
7.16
103.47
5.7
1.7
0.6
0.6
e9/l
0.25
229
253
254
285
7.04
101.44
5.8
1.7
0.0
0.0
e9/l
0.10
229
252
240
252
7.36
101.33
8.3
2.3
0.0
0.0
e9/l
0.50
191
199
268
322
6.72
100.73
5.7
1.7
1.8
2.0
e9/l
2.91
245
292
259
306
6.73
98.55
6.0
1.7
0.2
0.2
e9/l
0.03
236
279
129
52
16.28
96.94
2.4
1.4
0.3
0.3
e6/l
0.08
101
33
102
20
32.20
95.97
2.9
1.3
—
—
—
0
0
231
248
7.07
95.12
5.7
1.5
0.7
0.7
%
0.17
218
231
174
129
9.42
94.53
3.8
1.3
35.4
62.7
ng/l
0.21
103
30
240
272
6.78
94.24
6.0
1.9
8.4
8.0
%
0.70
230
257
237
270
6.71
92.45
5.8
1.7
2.9
3.2
%
0.75
224
254
129
58
14.57
92.27
2.2
1.3
—
—
—
0
0
253
321
6.15
89.08
5.7
1.8
27.9
32.2
%
6.15
242
300
112
39
18.35
88.87
3.3
1.6
93.6
90.9
%
0.27
112
39
484
1126
5.43
88.30
14.7
2.4
13.3
13.5
%
0.93
476
1067
248
311
6.17
88.18
5.5
1.6
58.1
53.8
%
4.90
238
295
154
108
9.64
86.28
3.3
1.2
56.1
68.4
u/l
0.70
149
102
101
34
18.65
80.91
2.1
1.4
4.6
2.9
e6/l
0.91
96
24
90
24
23.18
77.76
2.1
1.2
582.9
597.8
mosm/kgh2o
0.08
83
15
578
1710
6.07
73.93
11.2
2.3
—
—
—
0
0
121
74
10.51
73.16
8.0
1.8
—
—
—
0
0
326
620
4.49
71.55
3.4
1.6
—
—
—
0
0
372
788
4.37
71.30
3.5
1.9
14.8
14.6
pmol/l
0.74
346
691
457
1137
4.47
71.19
4.1
2.0
1.8
2.0
mu/l
1.62
431
1052
248
378
4.98
70.26
3.1
1.4
0.0
0.0
estimate
0.00
48
34
250
384
4.95
70.22
3.2
1.4
0.0
0.0
estimate
0.00
44
31
137
111
8.08
68.75
3.1
1.2
2.4
2.4
mmol/l
0.55
123
97
246
379
4.90
68.66
4.3
2.1
0.0
0.0
estimate
0.00
47
34
115
77
9.50
65.53
2.9
1.2
—
—
—
0
0
120
87
8.82
64.91
3.6
1.8
—
—
—
0
0
133
112
7.72
64.68
1.8
1.2
—
—
—
0
0
84
31
16.55
64.63
2.8
1.3
124.6
3997.5
ng/l
0.46
55
17
192
266
5.02
59.21
2.9
1.5
—
—
—
0
0
175
231
5.15
56.58
1.8
1.3
—
—
—
0
0
109
84
8.15
56.22
1.6
1.1
0.9
0.3
mg/l
1.70
88
58
66
19
20.68
55.29
2.8
1.3
—
—
—
0
0
578
1935
4.77
53.49
9.1
2.3
28.4
27.3
u/l
0.73
559
1859
622
2229
6.11
52.02
17.8
2.9
244.5
253.6
e9/l
3.14
610
2123
624
2252
6.15
51.29
17.9
2.9
6.6
6.1
e9/l
8.16
613
2134
623
2247
6.08
51.17
17.6
2.9
30.2
30.0
pg
2.24
614
2183
623
2247
6.08
51.17
17.7
2.9
90.0
89.1
fl
4.72
614
2182
623
2249
6.07
51.02
17.7
2.9
4.7
4.8
e12/l
14.28
612
2136
624
2257
6.12
50.92
17.8
2.9
140.0
144.8
g/l
12.02
615
2193
65
23
16.78
50.58
1.7
1.1
1024.6
996.8
nmol/l
0.06
53
16
171
258
4.44
46.94
2.1
1.5
—
—
—
0
0
131
165
5.07
43.71
3.2
1.6
0.0
0.0
estimate
0.49
44
33
112
121
5.78
43.45
3.2
1.4
—
—
—
0
0
91
80
6.94
42.11
1.9
1.4
2.7
2.6
mg/l
0.07
83
66
97
96
6.20
40.62
1.7
1.3
—
—
—
0
0
63
35
10.62
39.59
1.6
1.1
—
—
—
0
0
473
1533
3.12
39.50
3.7
2.2
5.8
5.6
mmol/l
3.93
444
1441
56
25
13.10
39.34
1.3
1.0
—
—
—
0
0
122
158
4.86
39.31
1.3
1.1
2.5
2.3
g/l
0.54
76
117
209
419
3.44
38.61
2.4
1.7
132.6
64.6
ug/l
3.40
193
402
85
81
6.33
36.66
1.3
1.1
21.0
20.4
nmol/l
0.12
76
72
83
77
6.49
36.62
2.3
1.2
133.8
100.0
ug/g
0.30
65
62
141
220
4.10
36.46
1.8
1.2
89.6
93.6
pmol/l
0.43
77
115
447
1440
2.92
36.46
4.6
2.7
39.1
36.8
mmol/mol
5.46
428
1379
120
164
4.58
36.30
3.2
2.4
125.5
143.1
mg/l
0.05
77
101
129
188
4.34
36.23
1.3
1.1
1.1
1.9
u/ml
0.41
38
51
79
71
6.67
35.76
1.3
1.1
4.3
12.1
u/ml
0.46
30
34
127
185
4.33
35.65
3.8
2.9
16.7
7.4
mg/mmol
0.61
83
133
148
244
3.90
35.62
2.7
1.4
—
—
—
0
0
82
78
6.32
35.39
1.3
1.0
14.0
20.5
iu/ml
0.45
27
23
40
10
22.91
34.72
4.4
1.1
—
—
—
0
0
118
165
4.46
34.70
3.1
1.5
1.0
1.0
kg/l
—
10
17
99
120
5.04
33.99
1.9
1.3
—
—
—
0
0
144
243
3.79
33.46
2.8
2.0
9.0
10.0
mmol/l
0.99
126
211
49
24
11.81
32.83
1.2
1.0
—
—
—
0
0
523
1900
3.01
32.58
3.9
2.4
2.8
3.1
mmol/l
14.67
495
1819
502
1786
2.90
32.36
3.4
2.3
1.3
1.3
mmol/l
0.54
476
1716
528
1932
3.03
32.35
12.7
2.6
41.2
42.3
%
2.52
446
1727
515
1876
2.91
31.20
3.6
2.4
1.4
1.4
mmol/l
3.12
489
1803
515
1884
2.88
30.69
3.7
2.4
4.6
5.0
mmol/l
16.05
491
1812
122
197
3.86
29.84
4.5
1.3
—
—
—
0
0
38
15
14.45
28.07
1.4
1.1
—
—
—
0
0
125
223
3.48
26.50
2.9
1.5
6674.5
3281.9
umol/l
0.31
116
211
49
35
8.08
26.21
1.4
1.1
—
—
—
0
0
39
5
44.64
26.18
8.1
5.4
—
—
—
0
0
58
52
6.50
26.16
1.7
1.3
—
—
—
0
0
41
7
33.58
26.14
4.4
1.4
17.4
1.5
ug/l
—
33
7
202
506
2.64
24.11
4.0
1.9
2.1
1.7
ug/l
0.78
183
473
68
83
4.81
22.94
2.2
1.4
—
—
—
0
0
36
20
10.22
22.47
3.6
1.2
4.5
4.9
pmol/l
0.72
30
15
32
15
12.06
21.81
5.4
1.5
—
—
—
0
0
32
15
12.06
21.81
3.0
1.1
—
—
—
0
0
77
111
4.10
21.48
1.8
1.4
382.4
383.1
pmol/l
0.01
70
104
41
32
7.31
20.55
2.9
1.4
—
—
—
0
0
28
12
13.12
19.88
1.5
1.0
—
—
—
0
0
26
12
12.14
17.82
1.5
1.0
—
—
—
0
0
26
12
12.14
17.82
1.5
1.0
—
—
—
0
0
113
246
2.78
17.00
1.7
1.3
1.5
1.4
mmol/l
0.18
98
223
28
17
9.25
16.56
1.0
1.0
—
—
—
0
0
19
0
+∞
15.42
1.8
0.0
13.4
—
ug/l
—
19
0
30
25
6.74
14.29
1.4
1.2
—
—
—
0
0
23
5
25.68
14.04
4.0
1.2
1.2
1.2
mmol/l
—
23
5
24
15
8.93
13.94
2.6
1.2
—
—
—
0
0
33
32
5.81
13.87
1.4
1.0
—
—
—
0
0
36
39
5.21
13.66
2.6
1.8
4.1
4.2
e9/l
0.08
31
32
62
107
3.35
13.51
1.7
1.1
—
—
—
0
0
23
6
21.39
13.43
2.2
1.3
—
—
—
0
0
34
36
5.32
13.19
1.1
1.1
997.3
116.2
u/ml
0.59
28
31
35
43
4.59
11.69
1.2
1.0
—
—
—
0
0
119
317
2.25
11.65
2.6
1.7
0.8
0.7
ug/l
0.37
72
127
31
34
5.12
11.63
2.5
1.9
—
8.1
—
0
9
40
58
3.90
11.03
1.1
1.0
—
—
—
0
0
39
57
3.86
10.65
1.2
1.1
72.2
174.2
iu/ml
1.44
14
29
13
0
+∞
10.53
1.7
0.0
10.0
—
mg/l
—
13
0
32
40
4.49
10.50
2.1
1.2
—
—
—
0
0
28
33
4.74
9.78
1.1
1.1
—
—
—
0
0
17
5
18.81
9.71
1.4
2.0
—
—
—
0
0
63
142
2.54
8.75
1.4
1.3
—
—
—
0
0
18
9
11.07
8.55
1.6
1.3
—
—
—
0
0
36
60
3.37
8.28
1.7
1.3
35.6
42.4
nmol/l
1.19
36
60
10
0
+∞
8.09
3.5
0.0
2.5
—
nmol/l
—
10
0
17
15
6.26
7.74
1.2
1.1
—
—
—
0
0
16
14
6.31
7.33
1.5
1.1
—
—
—
0
0
9
0
+∞
7.28
6.7
0.0
50.7
—
%
—
9
0
9
0
+∞
7.28
1.0
0.0
—
—
—
0
0
9
0
+∞
7.28
6.6
0.0
2.8
—
e9/l
—
9
0
9
0
+∞
7.28
3.1
0.0
9.2
—
kpa
—
9
0
9
0
+∞
7.28
3.1
0.0
5.1
—
kpa
—
9
0
14
6
12.85
7.16
3.6
1.2
—
—
—
0
0
8
0
+∞
6.47
3.7
0.0
—
—
—
0
0
8
0
+∞
6.47
3.7
0.0
4.0
—
mmol/l
—
8
0
8
0
+∞
6.47
1.8
0.0
0.4
—
nmol/l
—
8
0
8
0
+∞
6.47
3.8
0.0
107.4
—
mmol/l
—
8
0
18
21
4.74
6.38
1.1
1.0
—
—
—
0
0
14
8
9.64
6.38
1.4
1.0
—
—
—
0
0
16
17
5.19
6.21
1.2
1.0
—
—
—
0
0
14
13
5.93
6.11
1.3
1.1
—
—
—
0
0
17
20
4.69
5.98
1.6
1.5
—
—
—
0
0
7
0
+∞
5.66
1.3
0.0
—
—
—
0
0
7
0
+∞
5.66
2.4
0.0
—
—
—
0
0
7
0
+∞
5.66
1.3
0.0
—
—
—
0
0
11
5
12.07
5.59
1.5
2.2
—
—
—
0
0
25
43
3.23
5.54
1.1
1.0
—
—
—
0
0
12
7
9.42
5.48
1.8
1.3
—
—
—
0
0
20
30
3.69
5.35
1.8
1.9
—
—
—
0
0
82
258
1.82
5.02
1.4
1.2
—
—
—
0
0
6
0
+∞
4.85
1.3
0.0
—
—
—
0
0
6
0
+∞
4.85
10.0
0.0
30.5
—
umol/l
—
6
0
6
0
+∞
4.85
7.2
0.0
0.5
—
mmol/l
—
6
0
6
0
+∞
4.85
1.0
0.0
69.5
—
mmol/l
—
6
0
6
0
+∞
4.85
1.2
0.0
—
—
—
0
0
6
0
+∞
4.85
1.5
0.0
—
—
—
0
0
6
0
+∞
4.85
1.5
0.0
2.1
—
mmol/l
—
6
0
6
0
+∞
4.85
1.3
0.0
1904.0
—
u/l
—
6
0
13
15
4.76
4.67
2.3
1.1
—
—
—
0
0
5
0
+∞
4.04
2.2
0.0
—
—
nmol/l
—
0
0
5
0
+∞
4.04
1.4
0.0
—
—
—
0
0
5
0
+∞
4.04
1.6
0.0
93.1
—
%
—
5
0
5
0
+∞
4.04
1.0
0.0
—
—
—
0
0
5
0
+∞
4.04
2.6
0.0
—
—
—
0
0
5
0
+∞
4.04
3.4
0.0
—
—
—
0
0
5
0
+∞
4.04
3.8
0.0
42.2
—
nmol/l
—
5
0
5
0
+∞
4.04
1.0
0.0
7.1
—
ug/l
—
5
0
14
20
3.85
4.00
2.1
1.9
—
—
—
0
0
208
870
1.42
3.84
2.5
1.9
—
—
—
0
0
9
7
7.03
3.68
1.1
1.0
—
—
—
0
0
11
15
4.02
3.32
1.1
1.1
—
—
—
0
0
7
5
7.64
3.08
1.4
1.0
122.3
159.5
iu/ml
—
7
5
7
5
7.64
3.08
1.0
1.2
—
—
—
0
0
15
28
2.94
3.00
1.1
1.0
—
—
—
0
0
9
10
4.92
2.96
1.1
1.0
—
—
—
0
0
25
62
2.23
2.96
1.6
1.3
153.7
205.8
miu/ml
—
10
40
17
36
2.59
2.77
11.3
2.2
—
—
—
0
0
9
12
4.10
2.59
1.0
1.1
—
—
—
0
0
7
7
5.45
2.56
1.0
1.1
—
—
—
0
0
7
7
5.45
2.56
1.0
1.0
29.8
32.5
nmol/l
—
7
7
6
5
6.54
2.49
1.2
1.0
—
—
—
0
0
33
99
1.84
2.43
1.4
1.2
—
—
—
0
0
8
14
3.12
1.85
1.0
1.2
—
—
—
0
0
25
76
1.81
1.82
2.0
1.3
—
—
—
0
0
40
142
1.56
1.69
1.5
1.2
—
—
—
0
0
11
27
2.22
1.40
1.1
1.1
—
—
—
0
0
42
160
1.45
1.32
1.5
1.2
—
—
—
0
0
42
161
1.44
1.29
1.5
1.2
—
—
—
0
0
42
161
1.44
1.29
1.5
1.2
—
—
—
0
0
42
162
1.43
1.25
1.5
1.2
—
—
—
0
0
18
64
1.54
0.83
1.5
1.4
—
—
—
0
0
9
30
1.63
0.73
1.2
1.0
—
—
—
0
0
9
30
1.63
0.73
1.2
1.0
—
—
—
0
0
11
36
1.66
0.70
1.1
1.1
0.9
4.3
u/ml
—
5
11
87
525
0.88
0.47
1.4
1.3
—
—
—
0
0
44
272
0.87
0.36
1.4
1.3
—
—
—
0
0
5
21
1.29
0.23
1.0
1.3
—
—
—
0
0
5
26
1.04
0.09
2.0
1.1
0.9
1.0
g/l
—
5
26
23
117
1.07
0.06
1.9
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: ANY_HILMO – Any event in hilmo or specialist outpatient

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).