Risteys ·

OMOP concept ID	Test name	Measurement unit (harmonized unit)	N people	N records	Missing measurement value	Harmonized value distribution
3002109	kol/hdlsuh	— (—)	40358	66822	100.00%	Distribution not available
3002109	kol/hdl-su	— (—)	736	977	100.00%	Distribution not available
3002109	kol/hdl	— (—)	276	397	100.00%	Distribution not available
3002109	kolesterolinjahdl-kolest.suhde	— (—)	163	268	100.00%	Distribution not available

LabWAS

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

Diabetes, insulin treatment (Kela reimbursement)

2483

31889

0.45

314.35

2.0

1.7

—

Diabetes, insuline treatment (Kela reimbursement), excluding more controls

2439

31091

0.46

304.12

2.0

1.7

—

Insulin medication

724

21213

0.28

282.54

1.7

—

Type 2 diabetes, wide definition

1330

22179

0.37

279.83

2.0

1.8

—

Heart failure, not strict

872

18401

0.31

269.10

1.7

1.8

—

Diabetes medication

3090

34124

0.53

247.86

2.0

1.7

—

Insulin, combination of fast acting with intermediate-acting or long-acting

725

21195

0.30

243.61

1.7

—

Substance abuse, excluding more controls

1208

25575

0.39

229.87

1.7

—

Unspecified mental disorder

661

20914

0.29

227.94

1.5

1.7

—

Diabetes mellitus

3273

34122

0.55

227.60

2.0

1.7

—

Kela-code for severe mental illness

506

18414

0.26

226.18

1.6

1.7

—

Schizophrenia or delusion, excluding more controls

429

16882

0.23

224.86

1.5

1.7

—

Diabetes, varying definitions

3261

33908

0.55

223.46

2.0

1.7

—

Mental and behavioural disorders due to psychoactive substance use

1271

27084

0.42

203.03

1.6

1.7

—

Substance abuse

1208

26559

0.41

202.65

1.7

—

Insulin, intermediate and long-acting

661

19521

0.32

201.37

1.7

—

Schizophrenia or delusion

429

15910

0.25

198.98

1.5

1.7

—

Schizophrenia, schizotypal and delusional disorders

432

15914

0.25

197.93

1.5

1.7

—

Type 2 diabetes

3093

31293

0.56

195.24

2.1

1.7

—

Psychiatric diseases

4134

32860

0.61

190.55

1.6

1.7

—

Any mental disorder

4151

32948

0.61

189.96

1.6

1.7

—

1320

25470

0.44

184.84

1.7

—

1197

24430

0.43

182.60

1.7

—

Alcohol use disorder, Swedish definition

1108

23290

0.42

177.75

1.7

1.8

—

Mental and behavioural disorders due to alcohol

1037

23153

0.41

172.82

1.6

1.7

—

Other (not insulin) diabetes medications

2912

29413

0.58

171.69

2.1

1.7

—

Other bacterial diseases

2506

30080

0.56

171.03

1.7

—

Condition for Implicit Sepsis (Organ dysfunction codes)

2044

27054

0.53

166.51

1.7

—

Biguanides

2756

28447

0.58

162.32

2.0

1.7

—

Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism

2766

33052

0.58

161.81

1.7

—

Mental and behavioural disorders due to alcohol, excluding acute intoxication

811

19844

0.39

159.39

1.7

1.8

—

Insulin, fast-acting

435

14188

0.29

156.90

1.6

1.7

—

Benzodiazepine use

3171

36113

0.60

156.46

1.8

1.7

—

Insulin, fast-acting or short human

438

14149

0.29

154.71

1.6

1.7

—

Persons encountering health services for specific procedures and health care

3761

35817

0.63

152.66

1.7

—

Type 2 diabetes, strict (exclude DM1)

3015

29019

0.60

151.43

2.1

1.7

—

Pneumonia, organism unspecified

2679

31987

0.58

151.13

1.7

—

Type 2 diabetes, definitions combined

3014

28982

0.60

151.06

2.1

1.7

—

Pneumonia (excl. viral and due to other infectious organisms not elsewhere classified)

3124

34842

0.61

148.72

1.7

—

Alcohol use disorder, ICD-based

738

18248

0.38

148.45

1.7

1.8

—

Mood disorders, excluding more controls

3494

32876

0.62

146.34

1.6

1.7

—

Bleeding

1718

23098

0.52

146.22

1.8

—

Renal tubulo-interstitial diseases

2067

27732

0.55

145.83

1.7

—

Schizophrenia

7910

0.11

145.07

1.7

—

All pneumoniae

3342

35821

0.62

143.92

1.7

—

Pneumonias (Asthma/COPD co-morbidities)

3307

35650

0.62

143.75

1.7

—

Implicit Sepsis

1375

20983

0.49

142.93

1.7

—

Personality disorders, excluding more controls

605

15740

0.36

141.42

1.5

1.6

—

Type 2 diabetes, definitions combined, including avohilmo

3178

29313

0.62

137.01

2.1

1.7

—

Type 1 diabetes

383

12159

0.29

133.19

1.5

1.6

—

Sub-endpoint used in defining T1D endpoints

382

11912

0.30

130.09

1.5

1.6

—

Metabolic disorders

2963

28776

0.62

129.86

1.9

1.7

—

Other and unspecified nonorganic psychotic disorders

291

10435

0.26

129.13

1.5

1.6

—

Persons with potential health hazards related to family and personal history and certain conditions influencing health status

3044

31988

0.63

127.88

1.7

—

Influenza and pneumonia

3773

36726

0.66

127.82

1.7

—

Heart failure,strict

384

8841

0.30

127.21

1.6

1.9

—

Disorders of adult personality and behaviour

645

15581

0.39

125.58

1.5

1.6

—

Alcohol dependence

322

10870

0.28

124.53

1.7

1.8

—

Symptoms and signs involving cognition, perception, emotional state and behaviour

3012

32364

0.63

121.67

1.8

1.7

—

Heart failure, strict

394

8733

0.31

121.11

1.6

1.9

—

Mood disorders

3837

36769

0.67

120.42

1.6

1.7

—

Type 1 diabetes, wide definition

337

10811

0.29

120.00

1.5

1.6

—

Mood [affective] disorders

3835

36766

0.67

119.75

1.6

1.7

—

Personality disorders

605

14629

0.39

118.14

1.5

1.6

—

All-cause Heart Failure

382

8493

0.31

117.85

1.6

1.9

—

Depression

3628

36573

0.66

117.01

1.6

1.7

—

Type 1 diabetes, wide definition, subgroup 1

326

10450

0.29

116.39

1.5

1.6

—

Polyarthropathies

2123

23060

0.59

113.02

1.7

—

Tramadol

2642

26356

0.62

112.66

1.8

1.7

—

Hard cardiovascular diseases

1765

19312

0.57

111.27

2.0

1.8

—

Any mental disorder, or suicide (or attempt), or psychic disorders complicating pregnancy, partum or puerperum or nerve system disorders, excluding more controls

777

16631

0.44

110.98

1.5

1.6

—

Glucagon-like peptide-1 (GLP-1) analogues

690

12997

0.42

110.80

2.0

1.8

—

COPD/asthma/ILD related pneumonia or pneumonia derived septicaemia

3098

29019

0.65

109.56

1.7

—

3098

29019

0.65

109.56

1.7

—

Heart failure and antihypertensive medication

291

6476

0.28

109.49

1.7

—

Autoimmune diseases excluding thyroid diseases

4172

32788

0.69

108.43

1.6

1.7

—

Autoimmune diseases excluding thyroid diseases, strict definition

4100

32336

0.69

106.40

1.6

1.7

—

Oxycodone

316

9623

0.30

104.25

1.5

1.8

—

STROKE

1473

17684

0.56

100.00

2.0

1.8

—

Substance use, excluding alcohol

332

9671

0.32

98.34

1.6

1.7

—

Anxiety (asthma-related co-morbidities)

2562

30358

0.64

97.81

1.5

1.6

—

Other chronic obstructive pulmonary disease, including avohilmo

518

10529

0.40

97.24

1.7

1.9

—

Specific personality disorders

526

12412

0.40

96.79

1.5

1.6

—

Cerebrovascular diseases

1270

16273

0.54

95.59

1.9

1.8

—

Poisoning by drugs, medicaments and biological substances

507

12018

0.40

93.93

1.5

1.6

—

Parodontitis or operation codes

2833

30703

0.66

93.91

1.7

—

Parodontitis

2831

30688

0.66

93.56

1.7

—

Suicide or other Intentional self-harm

511

12023

0.40

92.74

1.6

1.7

—

Chronic periodontitis, including avohilmo

2828

30653

0.66

91.61

1.7

—

Spondylopathies

2508

22916

0.65

91.13

1.8

—

Disorders of lipoprotein metabolism and other lipidaemias

2272

21867

0.64

89.95

2.1

1.8

—

Any reimbursement code in KELA

3594

25222

0.69

89.36

1.6

—

Any mental disorder, or suicide (or attempt), or psychic disorders complicating pregnancy, partum or puerperium or nerve system disorders

777

15412

0.48

88.22

1.5

1.6

—

Cerebrovascular diseases (FINNGEN)

944

12680

0.51

87.73

1.9

1.8

—

Disorders of lens

1437

15342

0.57

87.59

1.9

—

Poisoning by medicine

451

10816

0.39

86.16

1.5

1.6

—

Hypertension, essential

3194

25873

0.68

85.65

1.9

1.7

—

Organic, including symptomatic, mental disorders

258

5963

0.30

85.35

1.6

1.8

—

COPD

384

8320

0.37

85.29

1.7

1.9

—

Major coronary heart disease event

1201

14112

0.55

85.08

2.1

1.9

—

Ischemic heart diseases

1899

18683

0.62

84.72

2.1

1.8

—

Acute alcohol intoxication

391

9931

0.37

83.76

1.7

—

Oral corticosteroids

4106

33766

0.72

83.44

1.7

—

Parodontitis and operation codes

2669

30127

0.67

82.88

1.7

1.8

—

All anxiety disorders

2601

30377

0.66

82.50

1.5

1.6

—

Stroke, including SAH

892

12528

0.51

82.20

1.9

1.8

—

Renal failure

336

8403

0.35

81.94

1.9

1.8

—

Major coronary heart disease event excluding revascularizations

996

12616

0.53

81.76

2.1

1.9

—

Insulin, fast-acting (human)

204

6942

0.27

81.68

1.4

1.6

—

Anaemias

1024

12128

0.53

81.11

1.6

—

Diseases of arteries, arterioles and capillaries

1033

13888

0.54

79.92

1.8

—

Dyspnoea

2661

29425

0.68

79.37

1.7

—

Heart failure and bmi 25plus

227

5129

0.29

79.33

1.7

1.9

—

Disorders of choroid and retina

1828

20678

0.63

78.08

1.8

—

Ischaemic heart disease, wide definition

1873

18124

0.63

77.60

2.2

1.8

—

Other anxiety disorders

1755

24014

0.62

76.89

1.5

1.6

—

Anxiety disorders, excluding more controls

3589

32466

0.71

76.64

1.6

1.7

—

Other chronic obstructive pulmonary disease

368

7800

0.38

76.32

1.7

1.9

—

COPD (mode)

269

6236

0.33

75.49

1.8

—

Asthma, unspecified (mode), excluding more controls

1673

20508

0.62

75.19

1.7

—

Hypertension

3449

26766

0.71

74.91

1.9

1.7

—

Hypertensive diseases

3451

26782

0.71

74.85

1.9

1.7

—

Bacterial Sepsis

518

10124

0.44

74.63

1.8

—

Bipolar affective disorders

443

10076

0.41

74.58

1.5

1.6

—

COPD, early/later onset

368

7766

0.39

72.82

1.7

1.9

—

ILD medications: immunosuppressive drugs

2073

29367

0.66

72.20

1.6

1.7

—

Pure hypercholesterolaemia

1767

18239

0.63

71.88

2.1

1.8

—

COPD, hospital admissions

368

7726

0.39

71.52

1.7

1.9

—

Asthma, unspecified (mode)

1677

20514

0.63

71.25

1.7

—

COPD related to multimorbidity

210

5703

0.30

71.23

1.8

1.9

—

Care involving use of rehabilitation procedures

1839

26344

0.64

70.63

1.7

—

Other retinal disorders

1041

14471

0.56

69.95

1.8

1.7

—

Disorders of gallbladder, biliary tract and pancreas

3285

28955

0.71

69.87

1.7

—

Stroke, excluding SAH

799

11077

0.52

69.55

1.9

1.8

—

Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances

347

8398

0.39

68.38

1.5

1.6

—

Implicit bacterial Sepsis

368

8173

0.40

68.08

1.8

—

Dental caries

554

11218

0.47

68.05

1.6

1.7

—

Senile cataract

1131

11848

0.58

67.95

1.9

—

Hypertensive diseases (excluding secondary)

2718

22067

0.69

67.84

1.9

1.7

—

Acute alcohol intoxication, ICD10

341

8330

0.39

67.61

1.6

1.7

—

Peripheral artery disease

295

6309

0.37

66.75

1.8

1.9

—

Other antidepressants

4431

30135

0.75

65.84

1.7

—

Inflammatory bowel disease treatment related agents

4848

35411

0.76

65.37

1.7

—

General examination and investigation of persons without complaint and reported diagnosis

2854

21007

0.70

64.37

1.6

1.7

—

Autoimmune diseases

5052

32992

0.77

64.35

1.6

1.7

—

General symptoms and signs

5178

33064

0.77

63.97

1.7

—

Non-selective monoamine reuptake inhibitors

797

13926

0.54

63.89

1.8

—

Alcohol abuse, main dg, excluding more controls

272

7094

0.36

63.63

1.6

1.7

—

Malaise and fatigue

1060

14797

0.58

63.61

1.7

—

Persons encountering health services in other circumstances, wide

5188

34258

0.77

63.42

1.6

1.7

—

Dentinal caries

457

9696

0.45

63.41

1.6

1.7

—

Diseases of arteries, arterioles and capillaries (FINNGEN)

561

7829

0.48

62.89

1.9

1.8

—

Myocardial infarction

752

9929

0.53

62.63

2.1

1.9

—

Coronary atherosclerosis

1403

14214

0.62

62.56

2.2

1.8

—

Mental and behavioural disorders due to multiple drug use and use of multiple drugs and use of other psychoactive substances

3673

0.15

62.51

1.4

1.6

—

Diseases of oesophagus, stomach and duodenum

4188

33102

0.75

62.49

1.8

1.7

—

Nerve, nerve root and plexus disorders

4001

32880

0.75

62.40

1.7

—

Secondary uncertain malignant neoplasm, excluding all cancers (controls excluding all cancers)

525

9445

0.47

62.36

1.6

1.8

—

Complications of surgical and medical care, not elsewhere classified

3463

33060

0.74

62.18

1.7

—

Dental pulpitis 4

4701

31244

0.77

60.33

1.6

1.7

—

Dental pulpitis 1

4705

31250

0.77

59.96

1.6

1.7

—

Acute and transient psychotic disorders

168

5346

0.29

59.68

1.5

1.7

—

Other heart diseases

2363

21774

0.69

59.24

1.8

1.7

—

Diseases of pulp and periapical tissues, including avohilmo

4712

31207

0.77

58.71

1.6

1.7

—

Angina pectoris

1027

11542

0.59

58.64

2.1

1.9

—

Bacterial infection, other or unspecified

888

13743

0.57

58.52

1.7

1.8

—

Neurotic, stress-related and somatoform disorders

3869

35668

0.75

57.97

1.6

1.7

—

Anxiety disorders

3895

35752

0.75

57.72

1.6

1.7

—

Use of hypnotics and sedatives

4327

32093

0.76

57.47

1.8

1.7

—

Type 1 diabetes, strict (exclude DM2)

185

5453

0.31

57.40

1.3

1.5

—

Other neurological diseases

1565

18887

0.65

57.07

1.9

1.8

—

Constipation

2503

24750

0.71

56.89

1.8

1.7

—

Type 1 diabetes, definitions combined

192

5518

0.32

56.57

1.3

1.5

—

ILD medications: prednisolone, methylprednisolone, prednisone

4741

33934

0.77

56.55

1.7

—

Asthma/COPD (KELA code 203)

3885

35340

0.76

55.50

1.6

1.7

—

Other disorders of fluid, electrolyte and acid-base balance

289

6810

0.40

55.11

1.6

1.8

—

Sulfonylureas

201

4660

0.34

55.09

2.2

1.8

—

Non-ischemic cardiomyopathy

214

4922

0.35

55.01

1.5

1.8

—

Dental pulpitis 1, only avohilmo

4816

31677

0.78

54.21

1.6

1.7

—

ILD medications

5053

34723

0.78

54.17

1.7

—

Dental pulpitis 4, only avohilmo

4806

31607

0.78

54.10

1.6

1.7

—

COPD, hospital admission 2, with asthma infections

202

4928

0.34

54.07

1.6

1.8

—

First line medication for Crohn's disease

5028

34333

0.78

53.90

1.7

—

Other degenerative diseases of the nervous system

355

6022

0.43

53.74

1.6

1.7

—

Fever of other and unknown origin

1619

21991

0.67

53.47

1.6

1.7

—

Intracranial trauma

2461

25102

0.71

53.44

1.6

—

Atherosclerosis, excluding cerebral and coronary sclerosis

255

5232

0.38

53.32

1.9

—

Ischaemic Stroke, excluding all haemorrhages

741

9881

0.55

53.07

1.9

1.8

—

Coronary revascularization (ANGIO or CABG)

607

7883

0.52

52.44

2.1

1.9

—

Explicit Sepsis

673

11542

0.54

52.01

1.6

1.7

—

Septicaemia

558

10122

0.52

51.58

1.6

1.7

—

Type 1 diabetes, strict definition

159

4756

0.31

51.35

1.4

1.5

—

Other disorders of ear

3020

26619

0.74

51.33

1.7

1.8

—

Dialysis, with operation codes

3577

0.20

51.16

1.4

1.8

—

Myocardial infarction, strict

700

9033

0.55

50.86

2.1

1.9

—

Chronic kidney disease

180

5229

0.33

50.64

1.9

1.8

—

Alcohol abuse, main dg

272

6458

0.40

50.60

1.6

1.7

—

Emotionally unstable personality disorder

276

6435

0.40

50.04

1.4

1.6

—

Persons encountering health services for other counselling and medical advice, not elsewhere classified

4799

34107

0.79

49.85

1.6

1.7

—

Dizziness and giddiness

2159

24184

0.71

49.67

1.8

1.7

—

Acute tubulo-interstitial nephritis

1459

19098

0.66

49.42

1.7

1.6

—

Type 1 diabetes, strict definition, subgroup 1

150

4527

0.30

49.38

1.4

1.5

—

Lower back pain or/and sciatica

4094

35903

0.78

49.28

1.7

—

Pain in limb

2946

28047

0.74

49.19

1.6

1.7

—

Early onset COPD, excluding more controls

302

6860

0.42

49.11

1.7

1.8

—

L04AA Selective immunosuppressants

415

8353

0.47

48.86

1.6

1.7

—

Atrial fibrillation and flutter

1172

11729

0.63

48.62

1.9

1.8

—

Nephropathy related operations

3403

0.21

48.45

1.4

1.8

—

Finngen Rheumatological endpoints

4521

32208

0.78

48.24

1.7

—

Low back pain

2891

29267

0.74

48.20

1.7

—

Dorsalgia

4517

30581

0.79

47.87

1.6

—

Other heart diseases, wide

4196

32706

0.78

47.71

1.8

1.7

—

Schizoaffective disorder

3406

0.22

47.61

1.7

—

Valvular heart disease excluding rheumatic fever

873

10461

0.60

47.52

1.9

1.8

—

Other septicaemia

463

8847

0.50

47.44

1.6

1.7

—

Symptoms and signs involving the urinary system

2056

21943

0.71

47.12

1.8

1.7

—

Atrial fibrillation and flutter with reimbursement

698

7709

0.56

47.04

2.0

1.8

—

Used for control exclusion in common control thyroid runs

5067

31684

0.80

46.99

1.6

1.7

—

Non-rheumatic valve diseases

865

10348

0.60

46.95

1.9

1.8

—

Erysipelas

1258

17223

0.65

46.63

1.7

1.8

—

Aplastic and other anaemias

544

9524

0.53

46.57

1.7

1.8

—

Endocrine, nutritional and metabolic diseases

4565

28900

0.79

46.49

1.7

1.6

—

Chronic lower respiratory diseases

5375

35566

0.80

46.30

1.7

—

Depression medications

2174

14883

0.71

46.03

1.6

1.5

—

Spondylosis

1411

17688

0.67

45.76

1.8

—

Problems related to lifestyle

172

4741

0.34

45.68

1.4

1.6

—

Dental caries 3

3471

22771

0.76

45.66

1.6

1.7

—

Convulsions, not elsewhere classified

589

10316

0.54

45.60

1.6

—

Presence of other functional implants

850

9859

0.60

45.41

1.8

—

Emergency coronary revascularization (for ACS)

640

8094

0.56

45.23

2.1

1.9

—

COPD, hospital admissions 1, only main diagnosis

252

5140

0.41

45.06

1.7

1.8

—

COPD, hospital admissions 3, with asthma pneumonia sepsis

117

3410

0.28

44.64

1.6

1.8

—

Mixed and other personality disorders

129

3997

0.30

44.34

1.5

1.7

—

Symptoms and signs involving the nervous and musculoskeletal systems

1488

21337

0.68

43.97

1.6

1.7

—

Heart failure and coronary heart disease

115

2937

0.29

43.42

1.8

1.9

—

Asthma, excluding more controls

3651

24627

0.77

43.41

1.6

1.7

—

Other reaction to severe stress, and adjustment disorders

1475

20970

0.68

42.93

1.5

1.6

—

Diseases of pulp and periapical tissues

1055

16025

0.64

42.86

1.7

—

Other soft tissue disorders, not elsewhere classified

3882

30050

0.78

42.83

1.7

1.6

—

Sciatica+with lumbago

1707

22550

0.70

42.66

1.7

—

Parasetamol

4433

27969

0.79

42.42

1.7

1.6

—

Malignant neoplasm of digestive organs, excluding all cancers (controls excluding all cancers)

618

8377

0.56

42.35

1.8

1.9

—

Early onset COPD

302

6495

0.45

42.29

1.7

1.9

—

Selective serotonin reuptake inhibitors

4661

30181

0.80

42.27

1.7

—

Diabetic retinopathy, excluding more controls

240

3218

0.41

41.90

1.8

2.0

—

Bacterial pneumoniae

850

11983

0.61

41.64

1.7

—

Dental caries 3, only avohilmo

3541

22927

0.78

41.63

1.6

1.7

—

Epilepsy

729

11942

0.59

41.56

1.6

1.7

—

Asthma

3674

24794

0.78

41.47

1.6

1.7

—

Secondary malignant neoplasm of other and unspecified sites, excluding all cancers (controls excluding all cancers)

186

4817

0.37

40.96

1.5

1.9

—

Hypertensive heart and/or renal disease

213

4071

0.40

40.96

1.7

1.8

—

Conductive and sensorineural hearing loss

2126

19814

0.73

40.76

1.8

—

Other specified and unspecified personality disorders

156

4250

0.34

40.73

1.6

—

Parodontitis or/and operation codes

2217

17603

0.73

40.56

1.7

—

Dental caries 1

3259

21212

0.77

40.24

1.7

—

Chronic diseases of tonsils and adenoids

5309

27750

1.24

40.22

1.7

—

Presence of cardiac and vascular implants and grafts

567

7539

0.56

40.15

1.9

—

Dental caries, including avohilmo

3258

21198

0.77

40.06

1.7

—

Malignant neoplasm

3595

26742

0.78

39.82

1.8

—

Diabetic nephropathy, excluding more controls

2416

0.22

39.66

1.8

2.1

—

Bacterial pneumonia, not elsewhere classified

775

11031

0.61

39.64

1.7

—

Other anaemias

499

8690

0.54

39.60

1.7

1.8

—

Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified (FINNGEN)

2379

19778

0.74

39.30

1.8

1.7

—

Other and unspecified anaemias

494

8609

0.54

38.95

1.7

1.8

—

Second line medication for Crohn's disease

1812

24605

0.72

38.88

1.6

1.7

—

Cardiovascular diseases (excluding rheumatic etc)

3937

28078

0.79

38.84

1.7

1.6

—

Transplanted organ and tissue status

3239

0.27

38.76

1.6

1.8

—

Mental and behavioural disorders due to sedatives or hypnotics

2870

0.23

38.76

1.3

1.7

—

Sodium-glucose co-transporter 2 (SGLT2) inhibitors

560

9606

0.56

38.64

2.2

1.8

—

Dental caries 3 and operation codes

3936

25019

0.79

38.18

1.6

1.7

—

Infections, IBD-co-morbidities

482

6277

0.53

38.15

1.7

—

Injuries to the head

4595

36384

0.81

38.10

1.6

1.7

—

Rheumatoid arthritis

708

10443

0.60

37.98

1.6

1.7

—

Type1 diabetes, definitions combined, early onset

124

3605

0.32

37.89

1.3

1.5

—

Other symptoms and signs involving the nervous and musculoskeletal systems

1100

16198

0.66

37.87

1.6

1.7

—

Spinal stenosis

981

11654

0.65

37.66

1.9

—

Asthma (only as main-diagnosis), excluding more controls

3288

24627

0.78

37.62

1.6

1.7

—

Any dementia, excluding more controls

108

2461

0.30

37.49

1.5

1.8

—

Care involving dialysis

2181

0.14

37.37

1.1

1.8

—

Dental pulpitis 2, only avohilmo

2992

19517

0.77

37.28

1.7

—

Dental pulpitis 2

2951

19287

0.77

37.22

1.7

—

Reimbursement for rheumatic diseases

1684

22933

0.72

37.07

1.6

1.7

—

L04AX Other immunosuppressants

1748

23690

0.72

37.05

1.6

1.7

—

Other diseases of pleura

559

8507

0.57

36.82

1.8

—

L04AD Calcineurin inhibitors

143

3882

0.35

36.54

1.5

1.7

—

Persons encountering health services in other circumstances

1162

16792

0.67

36.51

1.6

—

Coronary angioplasty

437

6158

0.53

36.31

2.1

1.9

—

Cholelithiasis, broad definition with cholecystitis

2854

24897

0.77

36.23

1.7

—

Nutritional anaemias

882

13143

0.64

36.18

1.7

—

Gonarthrosis [arthrosis of knee](FG)

2780

20919

0.77

36.13

1.9

1.8

—

Dementia, including avohilmo

175

3084

0.39

35.82

1.4

1.8

—

Dementia

148

2803

0.36

35.56

1.5

1.8

—

Sensorineural hearing loss

1875

17627

0.73

35.49

1.8

—

Diabetic retinopathy

265

3595

0.45

35.37

1.8

2.0

—

Asthma (only as main-diagnosis)

3295

24794

0.79

35.07

1.6

1.7

—

Dialysis

1120

0.07

35.03

1.0

1.8

—

Asthma (mode)

3672

24889

0.80

34.95

1.6

1.7

—

Use of disulfiram, acamprosate or naltrexone

161

4020

0.37

34.77

1.9

1.8

—

Cirrhosis, broad definition used in the article https://doi.org/10.1101/594523

127

3604

0.34

34.75

1.6

1.9

—

Asthma (diagnoses ohter than nonallergic)

3227

34348

0.79

34.60

1.6

1.7

—

Bacterial pneumonia (organism specified)

895

12321

0.65

34.41

1.7

—

Gonarthrosis,primary

2660

21369

0.77

34.35

1.9

1.8

—

Glomerular disorders in diseases classified elsewhere

101

3173

0.30

34.19

1.5

1.7

—

Cardiac arrhythmias

3198

26273

0.79

33.94

1.8

1.6

—

Dental caries 1, only avohilmo

3362

21384

0.79

33.84

1.7

—

Pain in throat and chest

3862

28846

0.80

33.77

1.8

1.7

—

Other cataract

736

8964

0.62

33.59

1.9

1.8

—

Any dementia

108

2360

0.32

33.55

1.5

1.8

—

Use of biperiden

1731

0.10

33.33

1.7

1.8

—

Chronic periapical parodontitis

461

8009

0.55

33.30

1.7

1.8

—

Coxarthrosis

1254

12046

0.69

33.30

1.9

—

Other symptoms and signs involving cognitive functions and awareness

773

11207

0.63

33.07

1.7

1.8

—

Coxarthrosis [arthrosis of hip](FG)

1282

13054

0.70

32.97

1.8

1.9

—

Persistent mood disorders

448

7815

0.55

32.88

1.6

1.7

—

Depression or dysthymia

3180

22124

0.79

32.50

1.7

—

Hypertensive Heart Disease

184

3576

0.41

32.50

1.6

1.8

—

Glomerular diseases

262

5361

0.47

32.12

1.8

1.7

—

Acute renal failure

160

3978

0.39

32.06

1.9

1.8

—

Benign neoplasm of colon, rectum, anus and anal canal

1379

13605

0.71

31.73

1.9

1.8

—

Viral hepatitis, IBD co-morbidity

132

3417

0.35

31.64

1.5

1.6

—

Dental caries 1 and operation codes

3778

23615

0.81

31.25

1.6

1.7

—

Other medical care

724

10933

0.63

31.23

1.6

1.7

—

Diverticular disease of intestine

2025

17553

0.75

31.21

1.9

1.8

—

Hypo-osmolality and hyponatraemia

124

3394

0.35

31.19

1.6

1.8

—

Non-invasive ventilation

698

10134

0.62

31.18

1.8

1.7

—

Iron deficiency anaemia

768

11597

0.64

31.07

1.6

1.7

—

Mental and behavioural disorders due to opioids

1892

0.17

30.79

1.3

1.6

—

Carpal tunnel syndrome

1981

23211

0.76

30.58

1.7

1.8

—

Phobic anxiety disorders

418

7222

0.55

30.57

1.5

—

Obesity due to excess calories

1585

21145

0.73

30.50

1.7

—

Other intervertebral disc disorders

3612

26908

0.81

30.33

1.8

1.7

—

Cholelithiasis

2779

24358

0.79

30.28

1.7

—

Any event in cancer register

4078

29095

0.82

30.23

1.7

—

Focal epilepsy

390

6911

0.55

30.09

1.7

—

Kidney transplant status

1679

0.13

30.07

1.2

1.8

—

Autoimmune diseases related-to ILD

3382

36268

0.81

30.00

1.6

1.7

—

Obesity

2324

29151

0.77

29.90

1.8

1.7

—

COPD/asthma/ILD related infections

4899

29080

0.83

29.88

1.6

1.7

—

COPD/asthma related infections

4899

29080

0.83

29.88

1.6

1.7

—

Alcoholic liver disease

2604

0.29

29.74

1.7

1.9

—

Coxibs

1562

6076

1.40

29.64

1.7

1.5

—

Alcohol withdrawal state with delirium

2164

0.23

29.62

2.0

1.9

—

Persistent delusional disorders

2404

0.26

29.49

1.6

1.7

—

Concussion

2186

24119

0.77

29.46

1.6

—

1466

0.08

28.80

1.5

1.9

—

Mental retardation, excluding more controls

1440

0.09

28.73

1.5

1.6

—

Obesity and other hyperalimentation

2347

29244

0.78

28.71

1.8

1.7

—

Migraine, single triptan purchase ok & required. ICD-code if available is included

5092

29304

1.20

28.59

1.7

1.6

—

Triptan medication for migraine, single purchase ok

5092

29304

1.20

28.59

1.7

1.6

—

Other arrhythmias

2338

22598

0.78

28.39

1.8

1.7

—

Osteopathies and chondropathies

1471

18677

0.73

28.38

1.7

—

Chronic periodontitis

235

4759

0.47

28.21

1.8

—

Chronic viral hepatitis

2626

0.31

28.16

1.5

1.6

—

Malignant neoplasm, wide definition for exclusion, excluding all cancers (controls excluding all cancers)

3895

27614

0.82

28.02

1.8

1.7

—

Malignant neoplasm, wide definition for exclusion

3895

27614

0.82

28.01

1.8

1.7

—

Malignant neoplasm, excluding all cancers (controls excluding all cancers)

3894

27608

0.82

28.00

1.8

1.7

—

Other nutritional deficiencies

2477

30176

0.79

27.73

1.8

1.7

—

Pain, not elsewhere classified

779

11504

0.66

27.62

1.7

—

Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified

3714

29083

0.82

27.62

1.7

—

ICD-8 DM (Sub-endpoint used for defining DM endpoints)

2070

0.24

27.53

1.5

1.8

—

Other menopausal disorders

1460

6198

1.40

27.41

1.8

1.6

—

Sequelae of cerebrovascular disease

373

5777

0.56

27.28

1.9

1.8

—

Other and unspecified iron deficiency

575

9006

0.62

26.59

1.7

—

Nausea and vomiting

549

8535

0.62

26.56

1.5

1.6

—

Diabetic retinopathy, strict definition

127

2811

0.38

26.36

1.4

2.0

—

Behavioural syndromes associated with physiological disturbances and physical factors

1115

15304

0.71

26.33

1.6

—

Fentanyl

1858

0.21

26.26

1.5

1.8

—

Nonorganic sleeping disorders, excluding more controls

591

9087

0.62

26.24

1.6

—

Extracorporeal dialysis

1514

0.14

26.20

1.1

1.8

—

Fall on same level

5457

35401

0.85

26.20

1.7

—

Recurrent or chronic depression

2102

19171

0.77

26.16

1.6

1.7

—

Diabetic nephropathy

2237

0.28

25.90

1.8

2.0

—

Hypothyroidism (congenital or acquired)

1860

13672

0.76

25.85

1.7

1.5

—

Other acute lower respiratory infections

1595

19880

0.75

25.83

1.6

1.7

—

Asthma-related infections

1885

23690

0.77

25.79

1.6

1.7

—

Asthma, hospital admission 2, infections

1885

23690

0.77

25.79

1.6

1.7

—

Complications of procedures, not elsewhere classified

2938

30913

0.81

25.73

1.7

—

Diseases of the digestive system

929

13146

0.69

25.71

1.6

1.7

—

Mental retardation, wide definition

1365

0.11

25.66

1.6

—

Focal epilepsy, strict definition

353

6139

0.56

25.47

1.7

—

Examination and observation for other reasons

2787

20775

0.80

25.45

1.6

1.7

—

Hypothyroidism and >3 levothyroxin purchases

1854

13611

0.76

25.28

1.7

1.6

—

Hypothyroidism, levothyroxine purchases

1854

13611

0.76

25.28

1.7

1.6

—

Dermatitis

1913

24330

0.77

25.28

1.7

—

Focal epilepsy, mode (most common among epilepsy diagnosis)

340

5954

0.55

25.22

1.7

—

Rheumatism, unspecified

244

4683

0.50

24.90

1.6

1.8

—

Other viral hepatitis

127

3028

0.39

24.88

1.5

1.6

—

Mental retardation

1300

0.11

24.60

1.5

1.6

—

Other dialysis

827

0.09

24.52

1.0

1.7

—

Rheumatoid arthritis, including avohilmo

813

11678

0.68

24.37

1.6

1.7

—

Degenerative diseases of the nervous system

111

2186

0.38

24.30

1.5

1.8

—

Mental and behavioural disorders due to use of other stimulants, including caffeine

1537

0.19

24.30

1.5

1.6

—

Behavioural and emotional disorders with onset usually occurring in childhood and adolescence

737

9729

0.66

24.25

1.4

—

Ulcer of lower limb, not elsewhere classified

2580

0.35

24.11

2.0

1.8

—

Opioids

5116

31154

0.85

24.08

1.7

1.6

—

Other disorders of teeth and supporting structures

493

7778

0.61

24.07

1.8

1.7

—

Unstable angina pectoris

438

5952

0.60

24.02

2.1

1.9

—

Use of eye-antiallergens (taken as indicator of allergic/atopic conjunctivitis)

3191

26111

1.23

23.96

1.7

1.6

—

Chronic pancreatitis

164

3552

0.44

23.91

1.8

—

Abnormalities of breathing

4395

30579

0.84

23.86

1.8

1.6

—

Retention of urine

434

6010

0.60

23.84

1.8

—

Viral hepatitis

153

3344

0.43

23.79

1.5

1.7

—

Oedema, not elsewhere classified

662

9776

0.66

23.78

1.7

—

Other disorders of skin and subcutaneous tissue

1877

21777

0.78

23.60

1.8

1.7

—

Nontraumatic intracranial haemmorrhage

180

3784

0.46

23.48

1.9

1.8

—

Dental operations

2785

17433

0.81

23.43

1.7

1.8

—

Postmenopausal atrophic vaginitis

1109

4824

1.42

23.41

1.9

1.7

—

Secondary malignant neoplasm of respiratory and digestive organs, excluding all cancers (controls excluding all cancers)

169

3617

0.45

23.36

1.6

1.8

—

Other special examinations and investigations of persons without complaint or reported diagnosis

3477

21008

0.83

23.34

1.7

—

Mental disorders, not otherwise specified

191

3840

0.47

23.32

1.5

1.6

—

Mental and behavioural disorders due to cannabinoids

1645

0.22

23.27

1.1

1.5

—

Gout

323

5143

0.56

23.02

1.9

—

Other disorders of urethra and urinary system

2281

21144

0.80

22.89

1.7

1.6

—

Gingivitis and periodontal diseases

4219

25542

0.84

22.85

1.6

1.7

—

Dental operations, only avohilmo

2943

18226

0.82

22.59

1.7

1.8

—

Respiratory diseases principally affecting the interstitium, IBD co-morbidites

178

2719

0.46

22.55

1.9

1.7

—

Acetic acid derivatives and related substances

1516

5991

1.34

22.53

1.7

1.5

—

Gonarthrosis

2478

17443

0.80

22.48

1.8

—

Diseases of liver

806

11406

0.69

22.46

1.8

—

GI-bleeding

459

7289

0.62

22.45

1.7

1.8

—

Benign neoplasm: Colon

1095

11355

0.73

22.34

1.9

1.8

—

Methotrexate

281

5004

0.54

22.29

1.6

1.7

—

Shoulder lesions

3119

22873

0.82

22.22

1.9

1.7

—

Unspecific neurodegenerative disorder

129

2108

0.42

22.21

1.5

1.8

—

Infections of the skin and subcutaneous tissue

2196

26937

0.80

22.14

1.6

1.7

—

Seropositive rheumatoid arthritis

495

7659

0.63

22.06

1.6

1.8

—

Viral Sepsis

273

4902

0.54

21.94

1.6

1.7

—

Implicit viral Sepsis

272

4889

0.54

21.94

1.6

1.7

—

Other diseases of the digestive system

466

7335

0.62

21.93

1.7

1.8

—

Hyperlipidaemia, other/unspecified

614

8641

0.66

21.90

2.0

1.8

—

Other and unspecified mood [affective] disorders

176

3553

0.47

21.89

1.6

—

Allergic conjunctivitis

3271

27096

1.21

21.78

1.7

1.6

—

Asthma-related pneumonia

703

10139

0.68

21.69

1.6

1.7

—

Accidental poisoning by and exposure to other and unspecified drugs, medicaments and biological substances

101

2519

0.38

21.57

1.6

—

Secondary hypertension

114

2693

0.40

21.57

1.8

1.7

—

Asthma-related pneumonia or sepsis

707

10163

0.68

21.43

1.6

1.7

—

Asthma, hospital admissions 3, pneumonia

707

10163

0.68

21.43

1.6

1.7

—

Other/unspecified dorsalgia

1202

15782

0.74

21.40

1.6

1.7

—

Other and unspecified dermatitis

1576

20048

0.77

21.00

1.7

—

Persons with potential health hazards related to socioeconomic and psychosocial circumstances

1074

14146

0.73

20.92

1.5

—

Other dorsopathies, not elsewhere classified

5074

30741

0.86

20.88

1.7

1.6

—

Cardiomyopathy

249

4521

0.54

20.86

1.6

1.8

—

Hypothyroidism, drug reimbursement

764

7664

0.69

20.85

1.7

1.6

—

Fibromyalgia

206

3900

0.50

20.84

1.5

1.7

—

Cutaneous abscess, furuncle and carbuncle

764

10722

0.69

20.67

1.6

1.7

—

Fracture of femur

221

3816

0.52

20.66

1.6

1.7

—

Assault

465

7102

0.63

20.45

1.5

1.6

—

Varicose veins

1683

16068

0.78

20.42

1.7

1.8

—

Intracranial injury

1837

22119

0.79

20.35

1.6

1.7

—

Rotator cuff syndrome

2158

19668

0.80

20.28

1.9

1.8

—

Disorders of psychological development

314

4881

0.57

20.25

1.4

—

Obesity related asthma

943

12762

0.72

20.13

1.8

1.7

—

Neurological diseases

4825

27923

0.86

20.08

1.7

1.6

—

Asthma, including avohilmo

5385

35651

0.87

19.93

1.6

1.7

—

Certain infectious and parasitic diseases

5164

29580

0.86

19.89

1.7

—

Malignant neoplasm of digestive organs

436

6707

0.63

19.73

1.8

1.9

—

Medical observation and evaluation for suspected diseases and conditions

3488

21008

0.84

19.70

1.7

—

COPD-related respiratory insufficiency

1621

0.26

19.70

1.7

1.9

—

Post-traumatic stress disorder

227

4097

0.53

19.69

1.6

1.5

—

Delirium, not induced by alcohol and other psychoactive substances

1663

0.27

19.66

1.6

1.8

—

ILD medications: azathioprine

414

6459

0.62

19.64

1.4

1.6

—

Amputation

1498

0.24

19.56

1.5

1.9

—

Ascites

1641

0.27

19.56

1.6

1.8

—

Azathioprine

414

6449

0.62

19.50

1.4

1.6

—

Syncope and collapse

1160

13495

0.75

19.47

1.7

—

Schizotypal disorder

1150

0.16

19.33

1.4

1.6

—

Other CVD (FINNGEN)

132

2268

0.44

19.29

1.8

1.7

—

Peripheral artery operations in Hilmo

1894

0.32

19.25

1.6

1.8

—

Cardiomyopathy (excluding other)

150

3107

0.47

19.14

1.6

1.8

—

Lung cancer and mesothelioma

169

2900

0.49

19.12

1.7

1.8

—

Panic disorder

536

7865

0.66

19.11

1.5

—

Diseases of oral cavity, salivary glands and jaws

4313

25547

0.86

19.09

1.7

—

Invasive ventilation

1768

0.31

19.06

1.7

1.8

—

Other disorders of glucose regulation and pancreatic internal secretion

107

2486

0.41

18.94

1.7

—

Other pulmonary diagnosis

4336

25029

0.86

18.76

1.7

—

Other/unspecified seropositive rheumatoid arthritis (ICD-10)

482

7261

0.65

18.75

1.6

1.7

—

Asthma, hospital admissions , main diagnosis only

3340

34975

0.84

18.72

1.6

1.7

—

Seropositive rheumatoid arthritis, wide

495

7406

0.65

18.59

1.6

1.7

—

Respiratory insufficiency

1233

0.19

18.54

1.8

—

Propionic acid derivatives

1596

6288

1.30

18.52

1.6

1.5

—

Other/unspecified seropositive rheumatoid arthritis

488

7314

0.65

18.49

1.6

1.7

—

Direct fill therapy

288

4824

0.58

18.46

1.5

1.7

—

Excluding asthma or asthma-COPD overlap

4342

25029

0.86

18.43

1.7

—

Cardiomyopathies, Primary/intrinsic

145

2996

0.47

18.39

1.5

1.8

—

Dental caries 2 and operation codes, only avohilmo

3640

19350

1.18

18.39

1.6

—

Other diseases of the respiratory system

189

3599

0.51

18.37

1.8

—

Other respiratory disorders and diseases

189

3599

0.51

18.37

1.8

—

Acute bronchitis

1051

13563

0.75

18.27

1.7

—

Complications of medical and surgical care

2393

27263

0.82

18.23

1.7

—

Female infertility, cervigal, vaginal, other or unspecified origin

1810

9766

1.27

18.17

1.6

1.5

—

Psychotic depression

110

2468

0.42

18.15

1.6

—

Hernia

3888

30482

0.85

18.14

1.8

1.7

—

Gastroduodenal ulcer

315

5175

0.60

18.04

1.6

1.8

—

Statin medication

3688

23994

0.85

17.97

2.2

1.6

—

Preparatory care for dialysis

1043

0.14

17.93

1.3

1.8

—

Sleep disorders

666

9320

0.69

17.90

1.6

—

ILD differential diagnosis

4328

24889

0.86

17.80

1.7

—

Chronic periodontitis, complicated

118

2572

0.44

17.70

1.6

1.8

—

Fenamates

771

3722

1.44

17.70

1.7

1.5

—

COPD differential diagnosis

4332

24898

0.86

17.67

1.7

—

Polycystic ovarian syndrome, consortium definition

2943

20930

0.84

17.65

1.6

—

Disorders of eyelid, lacrimal system and orbit

2922

26992

0.84

17.59

1.7

—

Gout, FINNGEN

323

5242

0.61

17.40

1.9

—

Headache

3041

29746

0.84

17.35

1.6

1.7

—

Hyperkinetic disorders, excluding more controls

380

5684

0.62

17.33

1.4

—

Anti-inflammatory and antirheumatic products, non-steroids

1583

6288

1.29

17.23

1.6

1.5

—

Pneumonitis due to solids and liquids

1425

0.27

17.10

1.5

1.8

—

Social phobias

256

4298

0.57

17.06

1.6

1.5

—

Osteoporosis

253

4134

0.57

16.95

1.7

1.8

—

Triptan medication for migraine, min. 3 purchases

3636

24845

1.18

16.93

1.6

—

Other diseases of intestines

5191

34040

0.88

16.58

1.7

—

Mild mental retardation

860

0.11

16.50

1.3

1.6

—

Lumbar disc prolapse

2712

25357

0.84

16.45

1.8

1.7

—

Cardiovascular diseases

4175

25968

0.86

16.45

1.7

1.6

—

1577

19323

0.80

16.44

1.6

—

Other mental disorders due to brain damage and dysfunction and to physical disease

1961

0.39

16.39

1.7

1.8

—

Alzheimer disease, excluding more controls

1263

0.37

16.39

1.5

1.8

—

Later onset COPD

1426

0.36

16.37

1.7

1.8

—

Generalized anxiety disorder

556

7876

0.68

16.36

1.5

—

Dorsopathies

5362

30821

0.88

16.33

1.6

—

Sulfasalazine

937

12302

0.75

16.33

1.6

1.7

—

Other diseases of blood and blood-forming organs, wide

434

6476

0.65

16.31

1.7

—

Systemic connective tissue disorders

770

10422

0.73

16.28

1.6

1.7

—

Other arthrosis

1846

16090

0.81

16.26

1.9

1.8

—

Gout, idiopatic and unspecified

260

4369

0.58

16.25

2.0

1.9

—

Alcohol-induced chronic pancreatitis

2130

0.41

16.22

2.0

1.9

—

Malignant neoplasm of bronchus and lung, excluding all cancers (controls excluding all cancers)

168

2671

0.52

16.20

1.7

1.9

—

Malignant neoplasm of respiratory system and intrathoracic organs, excluding all cancers (controls excluding all cancers)

226

3314

0.56

16.20

1.7

1.8

—

Symptoms and signs involving the digestive system and abdomen

5152

29134

0.88

16.16

1.7

—

Nonorganic sleeping disorders

591

8282

0.69

16.13

1.6

—

Other blood glucose lowering drugs, excl. Insulins

206

3664

0.55

16.11

2.1

1.8

—

Lung diseases due to external agents

120

2521

0.47

15.86

1.5

1.8

—

Open wound of head

1663

20059

0.80

15.81

1.6

1.7

—

Primary gonarthrosis, bilateral

962

11020

0.75

15.78

1.9

—

Hypokalaemia

142

2796

0.49

15.72

1.7

1.8

—

Later onset COPD, excluding more controls

1352

0.36

15.72

1.7

1.8

—

Conjunctivitis

4179

31992

1.15

15.71

1.7

1.6

—

Persons encountering health services in circumstances related to reproduction

3871

22919

1.16

15.64

1.7

—

Transient ischemic attack

900

9855

0.75

15.63

2.0

1.8

—

Paroxysmal tachycardia

791

8934

0.73

15.56

1.7

—

Obesity, other/unspecified

1246

15666

0.78

15.53

1.8

1.7

—

Venous thromboembolism

1228

15075

0.78

15.45

1.8

—

Dissocial personality disorder

789

0.11

15.42

1.2

1.8

—

Injuries to the thorax

1224

15449

0.78

15.40

1.7

—

Myocardial infarction, without ST-elevation

456

6190

0.67

15.39

2.1

1.9

—

Extreme obesity with alveolar hypoventilation

1112

0.23

15.38

2.0

1.8

—

Coronary artery bypass grafting

266

3342

0.60

15.12

2.1

1.9

—

Ill-defined and unknown causes of mortality

906

0.15

15.11

2.1

1.9

—

Intestinal stricture

518

7376

0.69

14.94

1.7

1.8

—

Cardiac arrest

1458

0.37

14.94

2.2

1.8

—

Volume depletion

1650

0.37

14.89

1.4

1.7

—

Cervical disc disorders

1120

14202

0.77

14.77

1.8

—

Female infertility

1949

9981

1.23

14.74

1.5

—

Neurological diseases, wide definition

2116

12672

0.82

14.69

1.6

1.5

—

DVT of lower extremities and pulmonary embolism

804

10625

0.74

14.68

1.8

—

Arthrosis

3254

20641

0.86

14.61

1.8

—

Secondary parkinsonism, excluding more controls

545

0.12

14.49

1.4

1.7

—

Intracerebral haemorrhage

1798

0.40

14.28

1.6

1.8

—

Polyneuropathies and other disorders of the peripheral nervous system

324

4986

0.64

14.08

1.9

1.8

—

Antihypertensive medication - note that there are other indications

4001

24807

0.87

14.07

1.7

1.5

—

Biological medication for rheuma

521

7255

0.70

13.92

1.5

1.6

—

Obsessive-compulsive disorder

183

3172

0.55

13.89

1.6

1.5

—

Abnormal findings on diagnostic imaging and in function studies, without diagnosis

1595

17949

0.81

13.78

1.8

—

Codeine

4981

30610

0.89

13.75

1.7

1.6

—

Gout, unspecified

202

3462

0.57

13.75

2.1

1.9

—

Polyarthrosis

304

4523

0.63

13.70

1.8

—

Wide developmental disorders, excluding more controls

1271

0.32

13.70

1.4

—

Hypoglycaemia, other or unspecified

2011

0.45

13.58

1.6

1.7

—

384

5623

0.66

13.55

1.5

1.6

—

Other gastritis (incl. Duodenitis)

417

6052

0.68

13.51

1.6

1.8

—

Agoraphobia

1544

0.38

13.51

1.3

1.5

—

Somatoform disorder

480

6743

0.69

13.36

1.8

1.7

—

Alzheimer’s disease, wide definition, excluding more controls

1105

0.39

13.36

1.6

1.8

—

Oxicams

1041

4607

1.31

13.27

1.8

1.6

—

Diarrhoea and gastroenteritis of presumed infectious origin

2965

30939

0.86

13.26

1.7

1.6

—

Cerebral palsy and other paralytic syndromes

212

3526

0.58

13.24

1.7

—

Intentional self-harm by sharp object

1046

0.27

13.23

1.6

1.5

—

Other systemic involvement of connective tissue (FG)

588

7956

0.72

13.14

1.7

—

Supplementary factors related to causes of morbidity and mortality classified elsewhere

942

12005

0.77

13.11

1.6

1.7

—

Haemorrhage from respiratory passages

711

8753

0.74

13.06

1.8

1.7

—

Mental and behavioural disorders due to tobacco

161

2852

0.54

12.99

1.8

—

Gout, strict definition

157

2835

0.54

12.96

2.1

1.9

—

Malignant neoplasm of respiratory system and intrathoracic organs

147

2500

0.53

12.93

1.7

1.8

—

Parkinson's disease, excluding more controls

115

2226

0.49

12.93

1.9

1.8

—

Other diseases of hard tissues of teeth

2953

25264

0.86

12.93

1.7

—

Lesion of ulnar nerve

348

5148

0.66

12.89

1.8

—

Fracture of lower leg, including ankle

1906

22482

0.83

12.81

1.7

—

Dislocation, sprain and strain of joints and ligaments of knee

3691

30335

1.15

12.76

1.7

—

Cystitis

4199

22781

1.14

12.74

1.7

1.6

—

Smoking dependency

161

2836

0.55

12.74

1.8

—

Amputation of toe

1074

0.28

12.73

1.5

1.9

—

Diseases of the myoneural junction and muscle

169

2956

0.56

12.70

1.7

—

Other arthritis (FG)

965

12217

0.78

12.69

1.7

—

Other abnormal uterine and vaginal bleeding

546

5355

0.71

12.67

1.6

—

Tobacco use

1822

0.44

12.63

1.5

1.7

—

Pain (limb, back, neck, head abdominally)

3971

22452

0.88

12.63

1.7

—

Paralytic ileus and intestinal obstruction

446

6317

0.69

12.60

1.7

1.8

—

Other and unspecified polyneuropathies, also in other diseases

261

4102

0.62

12.56

1.9

1.8

—

Disorders of conjunctiva

4410

32998

1.13

12.56

1.7

1.6

—

All influenza

678

8968

0.74

12.55

1.6

1.7

—

Other ill-defined and unspecified causes of mortality

754

0.15

12.52

2.3

1.9

—

Conduction disorders

495

5739

0.71

12.52

1.9

1.8

—

5252

30787

0.89

12.49

1.6

1.7

—

Symptoms and signs concerning food and fluid intake

157

2782

0.55

12.47

1.6

1.7

—

Soft tissue disorders

5356

30840

0.89

12.44

1.7

1.6

—

Injuries to the elbow and forearm

2635

27452

0.86

12.44

1.6

1.7

—

Other problems related to primary support group, including family circumstances

349

4981

0.66

12.41

1.5

1.6

—

Sequelae of external causes of morbidity and mortality

522

7170

0.71

12.36

1.7

—

Tumor necrosis factor alpha inhibitors

472

6535

0.70

12.26

1.6

—

Cirrhosis of liver, NAS

1026

0.28

12.26

1.6

1.8

—

Maltreatment syndromes

139

2501

0.53

12.25

1.4

1.6

—

Other and unspecified myopathies

1825

0.45

12.25

1.9

1.8

—

Diseases of the skin and subcutaneous tissue

5361

29782

0.89

12.23

1.7

—

Arthropathies in other diseases classified elsewhere

1119

0.31

12.21

1.5

1.7

—

Persons encountering health services for examination and investigation

3707

21008

0.88

12.17

1.7

—

Use of anticholinesterases

100

1666

0.48

12.15

1.5

1.8

—

N06DA Anticholinesterases

100

1666

0.48

12.15

1.5

1.8

—

Brachial plexus disorders

290

4368

0.64

12.11

1.6

1.7

—

Autism spe, excluding more controls

1008

0.28

12.10

1.2

1.4

—

Special screening examination for infectious and parasitic diseases

2277

14637

1.19

12.06

1.5

1.6

—

Other (seronegative) rheumatoid arthritis, wide

348

5102

0.67

12.04

1.6

1.7

—

Disorders of other endocrine glands

1356

16201

0.81

12.03

1.7

1.6

—

Deposits [accretions] on teeth

129

2299

0.52

12.00

1.6

1.7

—

Secondary parkinsonism+Parkinsonism in other disease

478

0.14

11.96

1.4

1.7

—

Pulmonary heart disease, diseases of pulmonary circulation

521

7130

0.72

11.91

1.8

—

Malignant neoplasm of bronchus and lung

107

1987

0.50

11.89

1.7

1.8

—

Suppurative and unspecified otitis media

1673

17596

0.83

11.72

1.5

—

Extrapyramidal and movement disorders

685

8980

0.75

11.66

1.8

—

Emphysema

1144

0.33

11.65

1.7

1.8

—

Secondary parkinsonism

468

0.14

11.65

1.4

1.7

—

Toxic effect of ethanol

1654

0.44

11.64

1.4

1.7

—

Decubitus ulcer and pressure area

846

0.23

11.63

1.5

1.8

—

Charcot foot

482

0.15

11.62

1.9

1.8

—

Fracture of rib(s), sternum and thoracic spine

650

8561

0.75

11.58

1.7

1.8

—

Insomnia

501

6816

0.71

11.57

1.6

—

Aneurysms, operations, SAH

284

4296

0.65

11.56

1.9

1.8

—

Persons with potential health hazards related to communicable diseases

1780

20788

0.83

11.55

1.6

—

Wide developmental disorders

1184

0.35

11.53

1.4

—

Adrenocortical insufficiency

1009

0.30

11.46

1.3

1.7

—

Diabetic neuropathy

1531

0.43

11.43

1.7

2.1

—

L01XE Protein kinase inhibitors

1110

0.33

11.42

1.3

1.8

—

Alzheimer disease

1294

0.45

11.42

1.5

1.8

—

Subarachnoid haemorrhage

123

2284

0.52

11.40

2.0

1.8

—

Speech and linguistic disorders, excluding more controls

241

3516

0.62

11.35

1.4

—

Autism

1004

0.31

11.31

1.2

1.4

—

Suppurative and necrotic conditions of lower respiratory tract

1219

0.36

11.28

1.7

1.8

—

Malignant neoplasm of breast, HER2-negative, excluding all cancers (controls excluding all cancers)

1504

11776

0.82

11.28

1.8

1.7

—

Seropositive rheumatoid arthritis, strict definition

298

4431

0.66

11.24

1.5

1.7

—

Autism spe

970

0.30

11.23

1.2

1.4

—

Nonischemic cardiomyopathy

1618

0.44

11.22

1.4

1.8

—

Malignant neoplasm of breast, excluding all cancers (controls excluding all cancers)

1505

11777

0.82

11.22

1.8

1.7

—

Drug-induced adrenocortical insufficiency

491

0.17

11.18

1.3

1.7

—

Agranulocytosis

185

3041

0.59

11.09

1.6

1.7

—

Hyperkalaemia

772

0.21

11.09

1.8

—

Acute pancreatitis

413

5778

0.70

11.06

1.8

—

Gonarthrosis, primary, with knee surgery

1058

10708

0.80

11.04

1.9

—

Hydrocephalus

1229

0.37

10.99

1.8

1.7

—

Radiculopathy

313

4597

0.67

10.98

1.7

1.8

—

Infective dermatitis

232

3608

0.63

10.96

1.6

1.7

—

Episodal and paroxysmal disorders

5648

31793

0.90

10.94

1.7

1.6

—

Alzheimer disease, including avohilmo

112

1551

0.52

10.94

1.5

1.8

—

Injuries to the hip and thigh

1083

12205

0.80

10.85

1.7

—

Acute pancreatitis (for exclusion)

413

5758

0.70

10.84

1.8

—

Hyperkinetic disorders

380

5265

0.69

10.83

1.4

—

Abdominal and pelvic pain

5260

29134

0.90

10.83

1.7

—

Vocal cord dysfunction

507

6334

0.72

10.83

1.7

—

Other functional intestinal disorders

1203

13942

0.81

10.82

1.7

—

Falls/tendency to fall

5867

32197

0.91

10.81

1.6

1.7

—

Disorders resulting from impaired renal tubular function

872

0.27

10.78

1.5

1.7

—

Unspecified kidney failure

1432

0.42

10.73

1.5

1.8

—

Cervicobrachial syndrome

744

9492

0.77

10.67

1.8

1.7

—

Pain in joint

2921

21929

0.87

10.64

1.7

—

Non-allergic asthma (mode), excluding more controls

531

7029

0.73

10.62

1.6

1.7

—

Fungal Sepsis

803

0.25

10.57

1.4

1.7

—

Papulosquamous disorders

1174

14263

0.81

10.56

1.7

—

Manic episode

1232

0.39

10.54

1.4

1.7

—

Disturbance of activity and attention

360

5003

0.69

10.49

1.4

—

Peripheral arterial reconstruction

1832

0.50

10.45

1.6

1.9

—

Dementia in Alzheimer disease

701

0.25

10.42

1.5

1.8

—

Acute alcohol intoxication ICD-9

899

0.30

10.32

2.2

1.9

—

Diabetes mellitus in pregnancy

1835

13870

0.84

10.31

1.5

—

Vitreous haemorrhage

143

2464

0.56

10.30

1.9

1.8

—

Intestinal infectious diseases

4120

35559

0.89

10.27

1.7

—

Combinations of oral blood glucose lowering drugs

630

8187

0.76

10.25

2.3

1.8

—

Other systemic involvement of connective tissue

602

7874

0.75

10.25

1.7

—

Other specified/unspecified arthritis

836

10480

0.78

10.22

1.7

—

Dependent personality disorder

708

0.22

10.22

1.5

1.8

—

Acute peritonitis

1461

0.44

10.22

1.6

1.8

—

Disorders of thyroid, IBD co-morbidities

917

8290

0.79

10.15

1.7

1.6

—

Unspecified haematuria

850

9142

0.79

10.14

1.9

1.8

—

Chronic ulcer of skin, not elsewhere classified

1347

0.42

10.10

1.7

1.8

—

Fibrosis and cirrhosis of liver

1658

0.48

10.10

1.5

1.8

—

Specific development disorders of scholastic skills

1812

0.50

10.06

1.4

—

Non-allergic asthma (mode)

531

6970

0.74

10.03

1.6

1.7

—

Diagnoses used for exclusion with ILD

532

7048

0.74

9.95

1.7

1.8

—

Other or unspecified ileus, impaction or obstruction

277

4088

0.67

9.94

1.7

1.8

—

Other diseases of upper respiratory tract

5956

28427

1.10

9.92

1.7

—

Deforming dorsopathies

883

10964

0.79

9.92

1.6

1.7

—

Pulmonary embolism

502

6705

0.74

9.88

1.8

—

Gastric ulcer

214

3328

0.63

9.85

1.7

1.8

—

Pulmonary heart disease

502

6699

0.74

9.83

1.8

—

Alzheimer’s disease (Late onset), excluding more controls

684

0.35

9.80

1.5

1.8

—

Duodenal ulcer

1838

0.51

9.79

1.6

1.9

—

Traumatic subdural haemorrhage

136

2311

0.57

9.73

1.6

1.8

—

Pacemaker

300

4234

0.68

9.67

1.8

—

Pain in thoracic spine

463

6202

0.73

9.67

1.6

1.7

—

Psoriasis

867

10745

0.79

9.61

1.7

—

Implicit fungal Sepsis

741

0.26

9.58

1.5

1.8

—

Paranoid personality disorder

694

0.24

9.58

1.1

1.7

—

Disorders of parathyroid gland

283

4081

0.67

9.58

1.7

1.8

—

Dissociative [conversion] disorders

1554

0.48

9.57

1.5

—

Persons encountering health services for specific procedures, not carried out

181

2869

0.61

9.56

1.6

1.7

—

Spondyloarthritis

533

6993

0.75

9.52

1.6

1.7

—

Artrosis, including avohilmo

4092

24852

0.90

9.50

1.8

1.7

—

Noninfective enteritis and colitis

1691

19676

0.85

9.46

1.6

1.7

—

Other disorders of adrenal gland

1282

0.43

9.38

1.3

1.6

—

Human immunodeficiency virus [HIV] disease

885

0.33

9.29

1.4

1.8

—

Exclusions for E4_PCOS_CONSORTIUM

3295

23062

0.89

9.26

1.7

1.6

—

Seronegative rheumatoid arthritis

228

3429

0.65

9.20

1.6

1.8

—

Other/unspecified rheumatoid arthritis

162

2633

0.60

9.19

1.6

1.8

—

Glomerulonephritis

188

2939

0.62

9.19

1.9

1.7

—

Fitting and adjustment of other devices

535

6531

0.75

9.18

1.7

1.8

—

Emotional disorders starting during childhood or adolecense, excluding more controls

114

1960

0.55

9.15

1.3

—

Trigger finger

384

5247

0.71

9.14

1.8

—

1085

0.40

9.11

1.7

1.8

—

Myocardial infarction, unclassifiable

162

2360

0.61

9.10

2.0

1.9

—

Lyme disease

946

7715

1.25

9.08

1.7

—

Other specific joint derangements/joint disorders

3760

27903

0.89

9.07

1.7

1.6

—

Parkinson's disease, strict definition, excluding more controls

111

1950

0.55

9.06

1.8

—

Trochanteric bursitis

286

4105

0.68

9.05

1.7

1.8

—

Other enthesopathies

1110

13330

0.82

9.04

1.8

—

Dysphagia

514

6745

0.75

9.02

1.8

1.7

—

Continuous positive airway pressure

666

7280

0.77

9.02

1.9

1.8

—

Drugs, medicaments and biological substances causing adverse effects in therapeutic use

168

2679

0.61

9.01

1.9

1.7

—

Drug-induced neutropenia

102

1848

0.53

8.97

1.6

1.7

—

Demyelinating diseases of the central nervous system

260

3766

0.67

8.97

1.6

—

Other and unspecified drugs and medicaments

145

2391

0.59

8.96

1.9

1.7

—

Codeine or tramadol medication

5588

33667

0.91

8.94

1.8

1.7

—

Assault by unspecified means

956

0.37

8.92

1.4

1.6

—

Adalimumab

273

3912

0.67

8.89

1.6

1.7

—

Primary_lymphoid and hematopoietic malignant neoplasms

381

5212

0.72

8.88

1.8

—

Gastro-oesophageal reflux disease

2539

25385

0.88

8.86

1.8

1.7

—

Missing teeth due to accident, extraction or parodontitis

233

3457

0.66

8.85

1.8

—

Ventral hernia

503

6595

0.75

8.81

1.9

1.8

—

Other spirochaetal diseases

956

7831

1.24

8.80

1.7

—

Secondary and unspecified malignant neoplasm of lymph nodes, excluding all cancers (controls excluding all cancers)

231

3439

0.66

8.80

1.6

1.8

—

Dipeptidyl peptidase 4 (DPP-4) inhibitors

143

2367

0.59

8.79

2.3

1.8

—

Hypothyroidism, strict autoimmune

3271

24121

0.89

8.78

1.7

—

Drug-induced hypoglycaemia without coma

385

0.17

8.75

2.6

1.6

—

Cardiomyopathy, other and unspecified

112

1967

0.55

8.75

1.6

1.8

—

Hypothyroidism, strict autoimmune, 3 medication purchases required

3457

26173

0.89

8.74

1.7

1.6

—

Type of accident

885

10829

0.80

8.73

1.6

1.7

—

Assault by bodily force

268

3830

0.67

8.71

1.5

1.6

—

Other condition

389

5247

0.72

8.59

1.6

1.7

—

Diplopia

248

3616

0.67

8.57

1.7

—

severe traumatic brain injury, does not include concussion

359

4928

0.72

8.57

1.7

1.8

—

KRA_PSY_EATING, excluding more controls

325

4474

0.70

8.56

1.5

1.4

—

Cellulitis

608

7735

0.77

8.56

1.7

—

Paracetamol of NSAID medication

1148

4786

1.23

8.55

1.6

1.5

—

MS-disease / Multiple Sclerosis

218

3231

0.65

8.55

1.5

1.6

—

Spondylopathies (FG)

501

6510

0.75

8.55

1.6

1.7

—

Malignant neoplasm of pancreas, excluding all cancers (controls excluding all cancers)

1238

0.45

8.52

1.8

1.9

—

Poisoning by narcotics and psychodysleptics [hallucinogens]

729

0.30

8.45

1.4

1.6

—

Weight loss

130

2176

0.58

8.44

1.6

1.7

—

Neuromuscular dysfunction of bladder

149

2407

0.60

8.41

1.9

1.7

—

Malignant neoplasm of skin, excluding all cancers (controls excluding all cancers)

1343

10823

0.84

8.40

1.8

—

Sequelae of injuries of head

107

1863

0.55

8.37

1.7

—

Mixed specific developmental disorders

574

0.25

8.34

1.4

1.2

—

Anankastic personality disorder

1596

0.52

8.33

1.6

—

Other headache syndromes

1719

19793

0.86

8.33

1.7

1.6

—

Iron deficiency anaemia secondary to blood loss (chronic)

251

3641

0.68

8.33

1.6

1.7

—

Endovascular or surgical operations to intracerebral aneurysms

1679

0.53

8.33

1.9

1.8

—

Disorders of synovium and tendon

2274

23156

0.87

8.29

1.7

—

Unspecified jaundice

1066

0.42

8.29

1.7

1.8

—

Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified

2690

15153

0.88

8.28

1.6

—

Acute suppurative otitis media

1285

14093

0.84

8.27

1.5

—

Oesophageal varices

904

0.37

8.27

1.3

1.9

—

Osteomyelitis

1482

0.50

8.26

1.6

1.8

—

Zoster [herpes zoster]

276

3923

0.69

8.18

1.7

—

Speech and linguistic disorders

242

3357

0.67

8.16

1.4

—

Pleural effusion

151

2428

0.61

8.15

1.7

1.8

—

Dental pulpitis 3

481

4516

0.75

8.15

1.2

—

Deviated nasal septum

1555

13392

1.18

8.14

1.9

1.8

—

Habit and impulse disorders

757

0.33

8.10

1.5

1.6

—

Human immunodeficiency virus [HIV] disease resulting in other conditions

812

0.35

8.08

1.4

1.8

—

Unspecified fall

1491

17180

0.85

8.03

1.7

—

Monoamine oxidase A inhibitors

300

4169

0.70

7.99

1.7

1.8

—

Fracture of foot, except ankle

863

10472

0.81

7.97

1.6

—

Symptoms and signs involving the circulatory and respiratory systems

5697

30902

0.92

7.97

1.7

1.6

—

Schizoid personality disorder

710

0.31

7.96

1.4

1.7

—

Otitis media, unspecified

316

4005

0.71

7.93

1.5

—

Contact with and exposure to communicable diseases

1554

17847

0.85

7.90

1.5

—

Blood alcohol or alcohol intoxication level

969

0.41

7.89

1.5

1.6

—

Pyothorax

886

0.38

7.89

1.8

—

Primary_lymphoid and hematopoietic malignant neoplasms

381

5116

0.73

7.89

1.8

—

Emotional disorders and disorders of social functioning with onset specific to childhood

125

2032

0.59

7.87

1.3

—

Pre-eclampsia or poor fetal growth

1354

15726

0.84

7.86

1.6

1.5

—

Unknown and unspecified causes of morbidity

165

2555

0.63

7.85

1.6

1.7

—

Superficial injury of head

636

7962

0.79

7.83

1.6

1.7

—

Special screening examination for other diseases and disorders

213

3131

0.66

7.82

1.4

1.6

—

Alcoholic gastritis

394

0.22

7.81

3.2

1.8

—

Other neurotic disorders

1474

0.52

7.80

1.5

1.8

—

Hyperplasia of prostate

949

6549

0.82

7.79

2.0

—

Abnormal findings on diagnostic imaging of lung

924

10864

0.82

7.76

1.9

1.8

—

Sequelae of injuries, of poisoning and of other consequences of external causes

807

9831

0.81

7.76

1.7

—

Hyperparathyroidism

243

3461

0.68

7.76

1.7

1.8

—

Toxic effects of substances chiefly nonmedicinal as to source

322

4393

0.71

7.74

1.6

—

Abnormal weight loss

113

1914

0.58

7.73

1.7

—

Coxarthrosis, primary

1161

11929

0.84

7.73

1.9

—

Status epilepticus

959

0.41

7.72

1.4

1.7

—

Other disorders of the musculoskeletal system and connective tissue

292

4053

0.71

7.66

1.7

1.8

—

Somnolence, stupor and coma

1137

0.46

7.66

1.7

—

Hepatic failure, not elsewhere classified

842

0.38

7.64

1.6

1.8

—

Adhesive capsulitis of shoulder

428

5608

0.75

7.64

1.7

1.8

—

Benign neoplasm of colon, rectum, anus and anal canal

1395

14660

0.85

7.63

1.9

1.8

—

Other CVD

192

2887

0.66

7.63

1.8

—

Any gastric operation

4875

26579

0.91

7.61

1.6

—

GASTRO-related operations

4875

26579

0.91

7.61

1.6

—

Spondylolisthesis/Spondylolysis

496

6365

0.77

7.56

1.8

—

Degeneration of the brain due to alcohol

485

0.20

7.56

1.6

1.9

—

Sequelae with surgical and medical care as external cause

385

5119

0.74

7.56

1.7

—

Injuries to the shoulder and upper arm

3266

30203

0.90

7.53

1.7

—

Malignant neoplasm of intrahepatic ducts, biliary tract and gallbladder

526

0.22

7.52

1.5

1.8

—

Elevated blood glucose level

148

2326

0.62

7.51

1.7

—

Psoriatic and enteropathic arthropathies

357

4771

0.73

7.50

1.7

—

Injuries to the abdomen, lower back, lumbar spine and pelvis

1109

13021

0.84

7.50

1.6

1.7

—

Other noninflammatory disorders of uterus, except cervix

482

4258

0.76

7.50

1.8

1.7

—

Degeneration of nervous system due to alcohol

482

0.20

7.49

1.6

1.9

—

Postprocedural musculoskeletal disorders, not elsewhere classified

1486

0.53

7.46

1.7

1.8

—

Exclusions for E4_PCOS_BROAD

496

6337

0.77

7.41

1.6

1.7

—

Other respiratory diseases principally affecting the interstitium

194

2886

0.66

7.34

1.9

1.8

—

Other malignant neoplasms of skin (=non-melanoma skin cancer), excluding all cancers (controls excluding all cancers)

1017

8323

0.83

7.31

1.8

—

Diseases of peritoneum

171

2594

0.64

7.30

1.8

1.7

—

Lateral epicondylitis

483

6169

0.76

7.29

1.8

—

Evidence of alcohol involvement determined by blood alcohol level

558

0.27

7.27

1.9

1.6

—

Glaucoma

1094

11361

0.84

7.26

1.8

—

Other diseases of pancreas

103

1752

0.57

7.24

1.7

1.8

—

Medical treatment for female infertility

1376

11875

1.18

7.22

1.5

—

Emotional disorders starting during childhood or adolescence

114

1863

0.59

7.22

1.3

—

Hernia of abdominal wall

1334

15487

0.85

7.21

1.9

1.8

—

Parkinson's disease, including avohilmo

120

1976

0.60

7.19

1.9

—

Gastrointestinal diseases

3897

21358

0.91

7.17

1.6

—

Hernia of abdominal wall, postoperative

473

6064

0.77

7.15

1.9

1.8

—

Soft tissue disorders related to use, overuse and pressure

789

9564

0.81

7.15

1.8

—

Myocardial infarction, with ST-elevation

190

2824

0.66

7.15

2.1

1.9

—

Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure

168

2541

0.65

7.12

1.5

1.7

—

Dental pulpitis 3, only avohilmo

440

4159

0.76

7.12

1.2

—

Psoriasis vulgaris

537

6764

0.78

7.08

1.7

—

Explicit bacterial Sepsis

171

2577

0.65

7.07

1.7

—

Malignant neoplasm of breast

1491

12391

0.86

7.04

1.8

1.7

—

Calcific aortic valvular stenosis, including rheumatic fever

241

3349

0.70

7.03

1.9

—

Use of other anti-dementia drugs

1001

0.48

7.01

1.6

1.7

—

Use of memantine

1001

0.48

7.01

1.6

1.7

—

Juvenile arthritis (FINNGEN)

127

2015

0.61

6.96

1.5

—

Operations 2 for CAVS

240

3333

0.70

6.95

1.9

—

Calcific aortic valvular stenosis, diagnosis (helper)

240

3333

0.70

6.95

1.9

—

Mixed disorders of conduct and emotions, excluding more controls

1055

0.47

6.93

1.3

—

Non-small cell lung cancer, excluding all cancers (controls excluding all cancers)

135

2020

0.62

6.92

1.7

1.9

—

Hallux valgus (acquired)

1092

9303

0.84

6.90

1.8

—

Unspecified dementia

526

0.29

6.90

1.3

1.8

—

Viral infections characterized by skin and mucous membrane lesions

1474

16905

0.86

6.90

1.7

—

Hypotension

134

2127

0.62

6.90

1.8

—

Haemorrhage in early pregnancy

1194

13555

0.85

6.90

1.5

1.6

—

Ulcerative colitis

904

10768

0.83

6.89

1.6

1.7

—

Vascular dementia

327

0.21

6.88

1.4

1.8

—

Calcific aortic valvular stenosis

241

3337

0.70

6.87

1.9

—

Calcific aortic valvular stenosis, operated

241

3337

0.70

6.87

1.9

—

Alzheimer’s disease, wide definition

1099

0.52

6.86

1.6

1.8

—

Corns and callosities

114

1860

0.60

6.85

1.8

—

Abnormal findings on examination of blood, without diagnosis

1123

12322

0.84

6.85

1.8

—

Parkinson's disease

115

1888

0.60

6.83

1.9

—

Secondary uncertain malignant neoplasm

159

2420

0.65

6.83

1.6

1.8

—

Fracture of shoulder and upper arm

985

11651

0.84

6.82

1.6

1.7

—

Mycoses

711

8659

0.81

6.79

1.6

1.7

—

Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis

2923

21612

1.11

6.74

1.6

—

Assault by sharp object

804

0.40

6.73

1.7

—

Inguinal hernia

2414

18142

0.89

6.73

1.8

1.7

—

Familial hypercholesterolemia

190

2786

0.67

6.72

1.9

1.8

—

Arthropathies

5216

28611

0.92

6.72

1.6

—

Malignant neoplasm of pancreas

775

0.39

6.70

1.6

1.8

—

Other diseases of spinal cord

858

0.42

6.66

1.6

1.7

—

Other and unspecified nerve root and plexus disorders, also in other diseases

615

7569

0.80

6.65

1.8

1.7

—

Malignant neoplasm of breast, HER2-negative

1417

11980

0.86

6.63

1.8

1.7

—

Bronchitis

4899

34649

0.92

6.62

1.6

1.7

—

Injuries to the ankle and foot

3391

33739

0.91

6.59

1.6

1.7

—

Fracture of forearm

1860

19646

0.88

6.58

1.6

1.7

—

Speech therapy

649

7953

0.81

6.56

1.7

—

Malignant neoplasm of intrahepatic ducts, biliary tract and gallbladder, excluding all cancers (controls excluding all cancers)

879

0.43

6.56

1.7

1.9

—

Dental caries 3 and operation codes, only avohilmo

1344

7806

0.85

6.53

1.6

—

Unspecified human immunodeficiency virus [HIV] disease

454

0.24

6.52

1.2

1.8

—

Fracture of lumbar spine and pelvis

341

4510

0.75

6.51

1.6

1.7

—

Poisoning by medicine, drug-induced

522

0.28

6.51

1.8

1.7

—

Algoneurodystrophy

1268

0.53

6.50

1.4

1.7

—

Preterm labour and delivery

983

11550

0.84

6.48

1.6

1.7

—

Infections of genitourinary tract in pregnancy

293

3935

0.73

6.47

1.5

—

Alcohol abuse counselling and surveillance

682

0.37

6.46

1.6

1.8

—

Speech disturbances, not elsewhere classified

110

1789

0.60

6.45

1.6

1.7

—

Factors influencing health status and contact with health services

1909

10811

0.88

6.44

1.7

—

Disorder of lipoprotein metabolism, unspecified

179

2627

0.67

6.42

2.2

1.8

—

Anaemia in chronic diseases classified elsewhere

435

0.22

6.38

1.7

—

Inflammatory bowel disease

1237

14277

0.86

6.37

1.5

1.7

—

Undefined dementia

511

0.30

6.34

1.3

1.8

—

Abnormal involuntary movements

294

3945

0.73

6.32

1.7

—

Other complications of surgical and medical care, not elsewhere classified

222

3109

0.70

6.32

1.7

—

Diseases of the ear and mastoid process

6233

33705

0.93

6.31

1.7

—

Other disorders of kidney and ureter

209

2965

0.69

6.30

2.0

1.8

—

Other symptoms and signs involving general sensations and perceptions

925

0.46

6.29

1.9

1.6

—

Malignant neoplasm of liver and intrahepatic bile ducts

336

0.23

6.29

1.6

1.8

—

Eating disorders

372

4809

0.75

6.29

1.5

1.4

—

Neovascular glaucoma

845

0.44

6.29

1.9

1.7

—

DVT of lower extremities

374

4861

0.76

6.29

1.7

1.8

—

Assault by blunt object

627

0.35

6.27

1.5

1.7

—

Glaucoma secondary to other eye disorders

843

0.44

6.25

1.9

1.7

—

Certain disorders involving the immune mechanism

537

6657

0.79

6.19

1.7

—

Complications of internal orthopaedic prosthetic devices, implants and grafts

323

4279

0.75

6.18

1.7

1.8

—

Mixed disorders of conduct and emotions

1014

0.49

6.17

1.3

1.2

—

Bell's palsy

289

3868

0.73

6.15

1.7

—

Poor fetal growth

539

6644

0.79

6.15

1.5

—

Idiopathic gout

1520

0.58

6.14

1.8

1.9

—

Hypermobility syndrome

162

2369

0.66

6.10

1.5

1.6

—

Paralytic strabismus

1624

0.59

6.10

1.6

1.8

—

Abnormalities of gait and mobility

144

2180

0.65

6.09

1.7

1.8

—

Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium

1798

13107

0.88

6.03

1.5

1.4

—

Attention to artificial openings

692

0.39

6.03

1.3

1.8

—

Drug-induced osteoporosis

265

0.18

6.01

1.6

1.7

—

Ankylosing spondylitis

279

3730

0.73

6.01

1.6

1.7

—

Other and unspecified psoriasis

120

1869

0.62

5.98

1.6

1.8

—

Alcohol-induced acute pancreatitis

1150

0.53

5.98

2.0

1.9

—

Chronic gastritis

484

6062

0.79

5.95

1.8

—

Strabismus

889

10449

0.84

5.95

1.6

—

Other noninfective gastroenteritis and colitis

664

8024

0.82

5.95

1.7

—

Enterocolitis due to Clostridium difficile

136

2072

0.65

5.95

1.8

1.7

—

Fracture of skull and facial bones

763

9092

0.83

5.93

1.7

—

Vitamin deficiency, wide

1294

0.55

5.92

1.6

1.7

—

Vitamin deficiency

1294

0.55

5.92

1.6

1.7

—

Endometriosis

1830

9668

1.14

5.91

1.6

1.5

—

Behavioural disorders, excluding more controls

1043

0.51

5.90

1.5

—

malignant neoplasm of male genital organs, excluding all cancers (controls excluding all cancers)

690

5102

0.82

5.90

1.9

2.0

—

Focal brain injury

143

2140

0.65

5.89

1.7

—

Other pleural conditions

1516

0.59

5.85

1.6

1.8

—

ILD, hospital admission 2, with pulmonary infections

1611

0.60

5.82

1.8

—

Outcome of delivery

1219

6559

1.18

5.81

1.5

1.6

—

Other disorders of breast

538

4358

1.26

5.80

1.6

—

Left ventricular outflow tract obstruction (LVOTO), broad definition

292

3856

0.74

5.80

1.8

—

Amiodarone users

109

1732

0.62

5.80

1.9

—

Nephrotic syndrome

853

0.46

5.80

2.1

1.7

—

Personal history of certain other diseases

749

0.43

5.79

1.4

—

Ulcer of oesophagus

1369

0.57

5.79

1.7

1.8

—

AV-block

188

2440

0.69

5.79

1.9

1.8

—

Toxic effect of other and unspecified substances

532

0.33

5.76

1.6

—

Other obstetric conditions, not elsewhere classified

1852

13449

0.88

5.76

1.5

1.4

—

Other endocrine disorders

1486

0.60

5.72

1.5

—

Viral pneumonia

309

4053

0.75

5.72

1.7

—

Intestinal malabsorption

1438

0.58

5.69

1.6

1.7

—

Plantar fascial fibromatosis

280

3712

0.74

5.69

1.8

—

Other diseases of biliary tract

107

1697

0.62

5.68

1.5

1.8

—

Dementia in other diseases classified elsewhere

575

0.36

5.66

1.6

1.7

—

5-aminosalicylic acid

879

10299

0.84

5.65

1.5

1.7

—

Visual impairment including blindness (binocular or monocular)

1332

0.57

5.62

1.4

1.7

—

Alzheimer’s disease (Late onset)

728

0.47

5.61

1.5

1.7

—

Other juvenile arthritis

110

1709

0.62

5.58

1.5

—

Failure and rejection of transplanted organs and tissues

406

0.25

5.57

1.1

1.8

—

D07AA Corticosteroids, weak (group I)

519

6366

0.80

5.57

1.6

—

Thrombocytopenia, unspecified

104

1647

0.62

5.56

2.0

1.7

—

Intestinal adhesions without obstruction

116

1796

0.63

5.55

1.5

1.8

—

malignant neoplasm of male genital organs

654

5027

0.82

5.54

1.9

—

834

0.47

5.54

1.3

1.7

—

Lichen simplex chronicus and prurigo

112

1740

0.63

5.54

1.9

1.8

—

Cerebral cysts

122

1855

0.64

5.52

1.7

1.6

—

Other disorders of skin and subcutaneous tissue, not elsewhere classified

281

3719

0.74

5.50

1.7

—

Use of donepezil

1001

0.53

5.50

1.6

1.8

—

Disorders of mineral metabolism

147

2158

0.67

5.48

1.6

1.7

—

Migraine without aura

930

10812

0.85

5.48

1.6

1.5

—

Streptococcal septicaemia

125

1897

0.65

5.46

1.7

—

Disorders of continuity of bone

258

3438

0.73

5.46

1.7

—

Adjustment and management of implanted device

210

2908

0.71

5.43

1.9

1.8

—

Atopic dermatitis, strict definition with reimbursement

1483

16192

0.88

5.40

1.6

—

Non-Hodgkin lymphoma, all, excluding all cancers (controls excluding all cancers)

190

2666

0.70

5.40

1.8

—

Drug-induced cataract

610

0.39

5.40

1.6

1.7

—

Visual disturbances and blindness

1554

17484

0.88

5.39

1.7

—

Diseases of vocal cords and larynx+other diseases of upper respiratory tract, no elsewhere classified

2553

22791

1.11

5.38

1.8

1.7

—

Abnormal findings in secretions and smears from cervix uteri vagina vulva

2695

19349

1.11

5.38

1.6

—

Myocarditis

143

2087

0.66

5.37

1.7

—

Juvenile rheumatoid arthirtis

1028

0.53

5.36

1.5

1.6

—

Cervicalgia

618

7440

0.82

5.36

1.7

—

Need for immunization against other single viral diseases

646

0.41

5.36

1.2

1.7

—

Symptoms and signs involving appearance and behaviour

265

0.21

5.36

1.2

1.6

—

Malignant neoplasm, without specification of site, excluding all cancers (controls excluding all cancers)

603

0.39

5.36

2.2

1.8

—

Isolated proteinuria with specified morphological lesion

299

0.25

5.35

1.0

1.7

—

Dermatitis and eczema

5128

35897

0.93

5.35

1.7

—

ILD, hospital admissions 3, with pneumonia sepsis

1216

0.57

5.35

1.9

1.8

—

Disorders of calcium metabolism

1447

0.60

5.35

1.7

—

IBD patients in KELA-register

952

11035

0.85

5.35

1.5

1.7

—

Chronic nephritic syndrome

1114

0.55

5.33

2.0

1.8

—

Vascular syndromes of brain in cerebrovascular disorders

615

0.40

5.32

2.0

1.8

—

Other fall from one level to another

701

8329

0.83

5.31

1.6

1.7

—

Psoriatic arthropathies

305

3955

0.75

5.29

1.8

1.7

—

Inflammatory bowel disease, strict (require KELA)

952

11025

0.85

5.29

1.5

1.7

—

Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure

1993

22005

0.90

5.28

1.7

—

All influenza (not pneumonia)

487

5984

0.80

5.28

1.6

1.7

—

Use of glatiramer acetate

770

0.46

5.27

1.5

1.6

—

Otitis externa

662

7900

0.83

5.25

1.8

1.7

—

Use of levodopa decarboxylase inhibitor

1438

0.61

5.24

1.8

—

Osteonecrosis

1472

0.61

5.22

1.8

—

Mixed connective tissue disease

131

1941

0.66

5.21

1.8

1.6

—

Other shoulder lesions

284

3704

0.75

5.18

1.6

1.7

—

Purpura and other haemorrhagic conditions

293

3814

0.76

5.15

1.9

1.7

—

Cholecystitis

208

2851

0.72

5.13

1.7

1.8

—

Diffuse large B-cell lymphoma, excluding all cancers (controls excluding all cancers)

714

0.45

5.13

1.8

—

Diffuse large B-cell lymphoma, helper endpoint

714

0.45

5.13

1.8

—

Aortic valve malfunction, age under 60 years

274

3582

0.75

5.12

1.8

—

Maternal care for other known or suspected fetal problems

1354

9811

0.87

5.11

1.4

1.5

—

Unspecified acute lower respiratory infection

462

5686

0.80

5.10

1.7

—

Personality and behavioural disorders due to brain disease, damage and dysfunction

388

0.27

5.10

1.2

1.7

—

Other maltreatment syndromes

100

1543

0.62

5.10

1.6

1.7

—

Fibroblastic disorders

557

6744

0.82

5.08

1.8

—

Non-small cell lung cancer

135

1991

0.67

5.01

1.7

1.8

—

Other eating disorders

153

2178

0.68

5.01

1.4

—

710

0.46

5.00

1.2

1.3

—

Open wound of ankle and foot

275

3587

0.75

5.00

1.6

1.7

—

Conduct disorder

981

0.53

5.00

1.4

1.5

—

Noninfectious colitis NAS

351

4446

0.78

4.99

1.7

—

Hyperkinetic disorders (excl. ADHD)

688

0.45

4.99

1.7

1.5

—

Diffuse large B-cell lymphoma

706

0.46

4.98

1.8

—

Pre-existing hypertension complicating pregnancy, childbirth and the puerperium

311

3970

0.76

4.97

1.8

1.6

—

Diseases of the musculoskeletal system and connective tissue

3574

19357

0.92

4.96

1.6

—

Immunodeficiencies

1425

0.61

4.94

1.6

1.7

—

Colorectal cancer, excluding all cancers (controls excluding all cancers)

433

5193

0.80

4.94

1.8

1.9

—

Other symptoms and signs involving the digestive system and abdomen

447

5507

0.80

4.94

1.7

—

Mental and behavioural disorders due to hallucinogens

245

0.22

4.93

1.2

1.5

—

Retinal breaks without detachment

504

4124

1.24

4.93

1.9

1.8

—

Otitis externa, unspecified

300

3860

0.76

4.92

1.8

1.7

—

Non-follicular lymphoma, hilmo, excluding all cancers

116

1748

0.65

4.91

1.7

1.8

—

Cytomegalovirus infection, IBD co-morbidity

638

0.43

4.90

1.8

1.7

—

Congenital malformations and deformations of the musculoskeletal system

265

3442

0.75

4.90

1.6

1.5

—

Communicating hydrocephalus

398

0.29

4.89

1.8

1.7

—

Malignant neoplasm of eye, brain and central nervous system, excluding all cancers (controls excluding all cancers)

131

1919

0.67

4.89

1.6

1.7

—

Other disorders starting during childhood or adolecense, excluding more controls

145

2001

0.68

4.88

1.4

1.3

—

Eating disorder

325

4123

0.77

4.88

1.5

1.4

—

Other/unspecified cytomegaloviral diseases

552

0.40

4.87

1.9

1.7

—

Other disorders involving the immune mechanism, not elsewhere classified

992

0.54

4.87

1.5

1.7

—

Abrasion of teeth

967

8192

0.86

4.86

1.7

1.6

—

Misadventures to patients during surgical and medical care

322

4108

0.77

4.86

1.7

—

Injury, poisoning and certain other consequences of external causes

3188

17312

0.92

4.85

1.6

1.7

—

Personal history of risk-factors, not elsewhere classified

448

0.34

4.84

1.1

1.6

—

Injury of other and unspecified intrathoracic organs

124

1829

0.66

4.83

1.6

1.8

—

Interstitial lung disease endpoints

165

2322

0.70

4.79

1.9

1.8

—

Interstitial lung disease

165

2322

0.70

4.79

1.9

1.8

—

Other interstitial pulmonary diseases

165

2321

0.70

4.77

1.9

1.8

—

Superficial injury of thorax

394

4898

0.79

4.77

1.7

—

Other and unspecified effects of external causes

1084

12347

0.87

4.76

1.6

—

Vertebral, anorectal, cardiavascular, thracheoesophagial, renal and limb anomaly

498

5843

0.81

4.76

1.7

1.6

—

Use of rivastigmine

686

0.46

4.76

1.4

1.8

—

Coagulation defects, purpura and other haemorrhagic conditions

506

6131

0.81

4.75

1.7

—

Abnormal findings on antenatal screening of mother

364

4538

0.78

4.75

1.4

—

Tonsillectomy and adenotomy

3934

25559

1.08

4.75

1.6

—

Cough

1396

15040

0.88

4.75

1.7

—

Ankylosing spondylitis, ICD10

272

3521

0.75

4.74

1.6

1.7

—

≡ Risteys

FG R12 + FR

FinnGen R11 + FinRegistry

FinnGen R10 + FinRegistry

FinnGen R10

FinnGen R9

FinnGen R8

FinnGen R7

FinnGen R6

FinnGen R5

FinnGen R4

FinnGen R3

Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma

Coding

Definition

OMOP mapping QC

Cohort

Year of birth distribution

Age at first measurement

Age at last measurement

Age at start of registry

Duration from first to last measurement

Statistics

Number of measurements over the years

Number of measurements per person

Distribution of lab values

Value range per person

LabWAS