Intermittent heterotropia

H7_INTERHETEROTRO

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

2 out of 7 registries used, show all original rules.

2445

4. Check minimum number of events

None

2445

5. Include endpoints

None

2445

6. Filter based on genotype QC (FinnGen only)

2445

Control definitions (FinnGen only)

Control exclude
H7_OCUMUSCLE

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 40828 21955 18837
Only index persons 29323 15895 13428
Unadjusted period prevalence (%)
Whole population 0.58 0.63 0.53
Only index persons 0.55 0.58 0.51
Median age at first event (years)
Whole population 5.28 5.40 5.07
Only index persons 6.80 7.08 6.45

-FinnGen-

Key figures

All Female Male
Number of individuals 2445 1619 826
Unadjusted period prevalence (%) 0.49 0.55 0.36
Median age at first event (years) 22.05 19.37 27.30

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
2174
Matched controls
21731
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
CEC10
NOMESCO Finland
Recession and resection of extraocular muscle
+∞
323.0
457
*
H50.52
ICD-10 Finland
Exophoria
884.7
323.0
369
5
H50.1
ICD-10 Finland
Divergent concomitant strabismus
3959.2
323.0
347
*
H50.31
ICD-10 Finland
Intermittent exotropia
15080.1
323.0
1314
*
H50.30
ICD-10 Finland
Intermittent esotropy
4067.8
323.0
620
*
3782B
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Intermittent heterotropia[STRABISMUS DIVERGENS INTERMITTENS]
+∞
307.7
288
*
H50.0
ICD-10 Finland
Convergent concomitant strabismus
2846.7
278.0
263
*
CEC00
NOMESCO Finland
Recession of extraocular muscle
+∞
254.2
239
*
3503
FHL
Single muscle retroposition
+∞
250.9
236
*
H53.2
ICD-10 Finland
Diplopia
18.1
138.4
221
135
3507
FHL
Retroposition and resection
+∞
124.1
118
*
H52.0
ICD-10 Finland
Hypermetropia
35.6
122.2
159
48
37301
ICD-8 Finland
Strabismus, Concomitans divergens
+∞
114.6
109
*
H50.2
ICD-10 Finland
Vertical strabismus
543.1
105.6
104
*
H53.0
ICD-10 Finland
Amblyopia ex anopsia
27.1
95.6
133
52
CEC30
NOMESCO Finland
Resection of extraocular muscle
+∞
93.4
89
*
H50.51
ICD-10 Finland
Esophoria
128.1
91.7
98
8
Z01.0
ICD-10 Finland
Examination of eyes and vision
3.2
80.0
490
1798
XCW99
NOMESCO Finland
Other investigative procedure of eye
4.4
79.9
316
803
H52.2
ICD-10 Finland
Astigmatism
27.2
75.0
104
40
H50.9
ICD-10 Finland
Strabismus, unspecified
54.5
66.4
79
15
H52.1
ICD-10 Finland
Myopia
9.5
59.5
126
140
H52.3
ICD-10 Finland
Anisometropia and aniseikonia
82.4
57.2
64
8
H50.3
ICD-10 Finland
Intermittent heterotropia
+∞
55.4
53
*
37303
ICD-8 Finland
Strabismus, Heterophoria (exophoria, esophroria, hypophoria)
+∞
49.1
47
*
3505
FHL
Single muscle resection
+∞
49.1
47
*
3782A
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Intermittent heterotropia[STRABISMUS CONVERGENS INTERMITTENS]
+∞
46.0
44
*
37300
ICD-8 Finland
Strabismus, Concomitans convergens
+∞
44.9
43
*
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
3.2
44.5
254
858
3781B
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Divergent concomitant strabismus[STRABISMUS DIVERGENS ALTERNANS]
+∞
43.9
42
*
H51.1
ICD-10 Finland
Convergence insufficiency and excess
+∞
42.8
41
*
H50.8
ICD-10 Finland
Other specified strabismus
+∞
40.7
39
*
3781A
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Divergent concomitant strabismus[STRABISMUS CONCOMITANS DIVERGENS]
+∞
38.6
37
*
H50.39
ICD-10 Finland
Intermittent heterotropia
198.3
37.9
39
*
WX140
NOMESCO Finland
Parabulbar anesthesy
5.7
35.2
105
193
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
2.9
34.1
227
847
CEC60
NOMESCO Finland
Transposition of extraocular muscle with adjustable suture
+∞
33.4
32
*
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
2.0
32.7
537
3115
CEW99
NOMESCO Finland
Other operation on extraocular muscle
+∞
32.4
31
*
F79.0
ICD-10 Finland
Unspecified mental retardation, with the statement of no, or minimal, impairment of behaviour
12.1
31.7
58
49
N03AG01
ATC
valproic acid; systemic, rectal
3.1
30.6
179
611
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
2.7
30.5
222
873
R62.0
ICD-10 Finland
Delayed milestone
5.7
30.5
90
164
3504
FHL
Retroposition of two muscles
295.5
28.8
29
*
XCK00
NOMESCO Finland
Perimetry
3.6
28.1
132
382
H49.2
ICD-10 Finland
Sixth [abducent] nerve palsy
146.8
27.7
29
*
F83
ICD-10 Finland
Mixed specific developmental disorders
5.4
27.3
84
161
F95
ICPC
Strabismus
263.4
25.7
26
*
AA1AD
NOMESCO Finland
CT of head and brain
2.0
25.1
352
1896
3784B
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Heterophoria[EXOPHORIA]
+∞
25.0
24
*
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.7
24.9
185
734
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.7
24.6
614
4034
N05AH04
ATC
quetiapine; oral
1.9
24.3
396
2257
N03AX11
ATC
topiramate; oral
4.3
24.2
91
217
F70.0
ICD-10 Finland
Mild mental retardation, With the statement of no, or minimal, impairment of behaviour
9.3
24.0
50
55
XA800
NOMESCO Finland
Neuropsychological investigation
3.0
23.4
141
491
CEC50
NOMESCO Finland
Advancement of extraocular muscle
+∞
21.9
21
*
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.5
21.6
183
780
WX408
NOMESCO Finland
General anesthesy, balanced
1.7
21.6
554
3648
ZXA10
NOMESCO Finland
Bilateral
1.9
21.5
348
1971
TCG00
NOMESCO Finland
Protection of cornea and sclera with soft lens
60.6
20.9
24
*
3780B
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Convergent concomitant strabismus[STRABISMUS CONVERGENS ALTERNANS]
+∞
20.9
20
*
H53.1
ICD-10 Finland
Subjective visual disturbances
2.9
20.8
129
457
H49.1
ICD-10 Finland
Fourth [trochlear] nerve palsy
211.8
20.6
21
*
RL140
NOMESCO Finland
NA
9.9
20.1
40
41
ZXA00
NOMESCO Finland
Right side
1.8
19.7
414
2554
G40.9
ICD-10 Finland
Epilepsy, unspecified
3.6
19.3
90
261
G80.2
ICD-10 Finland
Spastic hemiplegic cerebral palsy
31.6
19.3
25
8
ZXA05
NOMESCO Finland
Left side
1.8
18.4
380
2329
P85
ICPC
Mental retardation
11.1
18.2
34
31
N05AH03
ATC
olanzapine; systemic
2.4
17.9
157
682
Z01.1
ICD-10 Finland
Examination of ears and hearing
1.9
17.6
285
1607
G80.1
ICD-10 Finland
Spastic diplegic cerebral palsy
18.8
17.3
26
14
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
2.6
17.3
127
502
F82
ICD-10 Finland
Specific developmental disorder of motor function
5.0
17.2
55
112
N05AX08
ATC
risperidone; systemic
2.3
17.1
163
738
H55
ICD-10 Finland
Nystagmus and other irregular eye movements
12.1
16.8
30
25
N06AX11
ATC
mirtazapine; oral
1.6
16.8
544
3772
Z96.1
ICD-10 Finland
Presence of intraocular lens
2.4
16.7
141
600
H50.4
ICD-10 Finland
Other and unspecified heterotropia
+∞
16.7
16
*
CEC20
NOMESCO Finland
Recession and advancement of extraocular muscle
+∞
16.7
16
*
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.6
16.5
488
3303
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
2.2
16.5
174
828
N05BA09
ATC
clobazam; oral
5.8
16.3
46
81
H53.3
ICD-10 Finland
Other disorders of binocular vision
15.4
16.2
26
17
TPH04
NOMESCO Finland
Cathetrisation of vein
1.7
16.1
344
2123
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
3.3
15.6
79
245
H50.50
ICD-10 Finland
Alternating hyperphoria
+∞
15.6
15
*
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.8
15.4
298
1782
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
3.7
15.4
68
190
N03AX09
ATC
lamotrigine; oral
2.4
15.2
135
591
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
2.3
14.9
135
596
F79.9
ICD-10 Finland
Unspecified mental retardation, without mention of impairment of behaviour
21.2
14.6
21
10
N03AX12
ATC
gabapentin; oral
1.9
14.6
230
1283
H50
ICD-10 Finland
Other strabismus
150.9
14.5
15
*
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.0
14.4
179
912
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
3.1
14.2
78
258
N03AX16
ATC
pregabalin; oral
1.7
14.2
343
2188
G47.3
ICD-10 Finland
Sleep apnoea
1.7
13.8
285
1736
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.5
13.8
638
4759
N03AX14
ATC
levetiracetam; systemic
3.2
13.6
71
227
SPAT1229
SPAT
Assessment of need for aid
2.5
13.4
108
450
N06AX16
ATC
venlafaxine; oral
1.7
13.2
274
1673
H52.5
ICD-10 Finland
Disorders of accommodation
40.3
13.1
16
*
N05AH02
ATC
clozapine; systemic
3.5
13.1
61
179
SPAT1240
SPAT
Therapeutic discussion
1.7
13.0
298
1871
R1230
NOMESCO Finland
Neuropsychological evaluation of need and possibilities to rehabilitation
3.6
12.7
57
163
SPAT1216
SPAT
Assessment of functional ability
1.8
12.6
217
1245
N03AF02
ATC
oxcarbazepine; oral
2.8
12.5
78
281
F71.0
ICD-10 Finland
Moderate mental retardation, with the statement of no, or minimal, impairment of behaviour
17.4
12.5
19
11
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.1
12.5
139
678
R42
ICD-10 Finland
Dizziness and giddiness
1.6
12.4
311
1999
602
Kela drug reimbursment
Children's severe malnutrition
4.0
12.3
49
126
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
2.5
12.3
96
394
WX100
NOMESCO Finland
Conjunctival surface anesthesia
2.2
12.3
123
571
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.8
12.2
222
1299
R1260
NOMESCO Finland
Evaluation of communicative skills
4.6
12.2
41
90
SPAT1310
SPAT
Counselling related to known health issue
1.4
12.2
666
5116
G80.9
ICD-10 Finland
Cerebral palsy, unspecified
26.8
12.0
16
6
R51.80
ICD-10 Finland
Headache
1.6
12.0
338
2239
R06.5
ICD-10 Finland
Mouth breathing
2.0
12.0
150
766
N03AE01
ATC
clonazepam; systemic
2.5
11.9
96
401
SPAT1263
SPAT
Sampling
1.4
11.9
856
6906
Z01.8
ICD-10 Finland
Other specified special examinations
1.6
11.8
363
2462
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
1.9
11.8
188
1052
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.6
11.7
298
1923
L28
ICPC
Limited function/disability (L)
1.8
11.7
202
1160
183
Kela drug reimbursment
Lamotrigin and topiramate
4.2
11.7
43
103
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
1.7
11.7
263
1640
N06AB04
ATC
citalopram; systemic
1.6
11.6
334
2224
N05BA01
ATC
diazepam; systemic, rectal
1.8
11.6
213
1249
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.0
11.5
139
701
N04AA02
ATC
biperiden; systemic
3.8
11.5
48
129
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
2.2
11.5
118
556
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.7
11.5
231
1395
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
4.1
11.5
44
110
RT150
NOMESCO Finland
NA
5.5
11.5
33
61
H49.0
ICD-10 Finland
Third [oculomotor] nerve palsy
+∞
11.5
11
*
3780A
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Convergent concomitant strabismus[STRABISMUS CONCOMITANS CONVERGENS]
+∞
11.5
11
*
N02BE01
ATC
paracetamol; systemic, rectal
1.4
11.4
1529
13659
M03BX01
ATC
baclofen; systemic
4.4
11.4
40
92
R50.9
ICD-10 Finland
Fever, unspecified
1.6
11.4
296
1923
C07AA05
ATC
propranolol; systemic
1.6
11.4
368
2523
M41.4
ICD-10 Finland
Neuromuscular scoliosis
15.1
11.3
18
12
N02AX02
ATC
tramadol; systemic, rectal
1.4
11.3
572
4316
N05AB03
ATC
perphenazine; systemic, rectal
2.8
11.2
70
252
SPAT1301
SPAT
No procedures
1.4
11.2
593
4507
G40.20
ICD-10 Finland
Complex partial seizures with only alteration of consciousness
5.5
11.2
32
59
TAB00
NOMESCO Finland
Lumbar puncture
2.3
11.1
98
430
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
2.2
11.1
112
521
A06AD11
ATC
lactulose; oral
1.8
11.1
186
1060
G91.1
ICD-10 Finland
Obstructive hydrocephalus
9.2
11.0
22
24
NA7EA
NOMESCO Finland
Scoliosis X-ray examination
3.7
11.0
46
125
R5140
NOMESCO Finland
Monitoring the use of the aid
2.0
10.9
139
717
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
1.8
10.8
200
1176
H04.10
ICD-10 Finland
Dry eye syndrome
2.0
10.8
144
756
CA1CG
NOMESCO Finland
Eye and orbita extensive MRI examination with high intensity magnet
7.2
10.7
25
35
XKD00
NOMESCO Finland
Uroflowmetry
1.8
10.7
174
980
UKC02
NOMESCO Finland
Cystoscopy
1.8
10.7
188
1087
CE2W4
NOMESCO Finland
Eye movement mapping
21.5
10.7
15
7
N06AX21
ATC
duloxetine; oral
1.8
10.7
179
1021
RT190
NOMESCO Finland
NA
12.9
10.6
18
14
AA1BM
NOMESCO Finland
MRI examination of brain with 3 Tesla magnet
4.5
10.5
36
81
N04BA02
ATC
levodopa and decarboxylase inhibitor; oral
3.5
10.5
47
135
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.5
10.5
395
2798
R56.8
ICD-10 Finland
Other and unspecified convulsions
2.1
10.4
122
609
G80.3
ICD-10 Finland
Dyskinetic cerebral palsy
110.4
10.4
11
*
3783A
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Other and unspecified heterotropia
+∞
10.4
10
*
R1410
NOMESCO Finland
Drawing up a rehabilitation plan
7.7
10.4
23
30
N05AX12
ATC
aripiprazole; systemic
2.1
10.4
115
562
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
1.8
10.3
168
947
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
2.2
10.2
102
475
RT490
NOMESCO Finland
NA
9.6
10.2
20
21
G81.1
ICD-10 Finland
Spastic hemiplegia
23.5
10.2
14
6
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.5
10.2
393
2797
H03AA01
ATC
levothyroxine sodium; systemic
1.5
10.2
348
2413
N03AF01
ATC
carbamazepine; oral, rectal
2.6
10.2
75
298
SPAT1312
SPAT
General health counselling
1.4
10.2
742
5957
M02AA10
ATC
ketoprofen; topical
1.7
10.1
210
1277
Z46.8
ICD-10 Finland
Fitting and adjustment of other specified devices
3.5
10.1
45
129
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
1.8
10.0
159
891
RT274
NOMESCO Finland
NA
14.6
10.0
16
11
N04BC05
ATC
pramipexole; oral
2.2
10.0
100
467
H50.59
ICD-10 Finland
Heterophor UNS
40.2
10.0
12
*
H25.0
ICD-10 Finland
Senile incipient cataract
2.7
9.9
64
238
N05AA02
ATC
levomepromazine; systemic
2.6
9.9
73
291
N05BA06
ATC
lorazepam; systemic, sublingual
2.5
9.8
77
320
N05CD08
ATC
midazolam; nasal, systemic
3.0
9.8
56
192
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
1.9
9.8
147
807
Z87.6
ICD-10 Finland
Personal history of certain conditions arising in the perinatal period
3.1
9.7
51
166
F71.1
ICD-10 Finland
Moderate mental retardation, significant impairment of behaviour requiring attention or treatment
55.2
9.6
11
*
G44.2
ICD-10 Finland
Tension-type headache
1.6
9.5
238
1528
M79.6
ICD-10 Finland
Pain in limb
1.4
9.5
575
4456
SPAT1153
SPAT
Removal of sutures
1.4
9.5
450
3335
AAF20
NOMESCO Finland
Revision of shunt of ventricle of brain
15.1
9.5
15
10
XKD06
NOMESCO Finland
Physiologic investigation of micturition
3.1
9.5
49
158
H02.4
ICD-10 Finland
Ptosis of eyelid
3.5
9.4
43
126
WX110
NOMESCO Finland
Local anesthesy
1.3
9.4
1430
12794
H51.9
ICD-10 Finland
Disorder of binocular movement, unspecified
100.4
9.4
10
*
N05BA04
ATC
oxazepam; oral
1.5
9.4
399
2893
H51.8
ICD-10 Finland
Other specified disorders of binocular movement
+∞
9.4
9
*
N05CF01
ATC
zopiclone; oral
1.5
9.4
408
2977
N06AA09
ATC
amitriptyline; systemic
2.0
9.3
120
622
F70.1
ICD-10 Finland
Mild mental retardation, Significant impairment of behaviour requiring attention or treatment
8.1
9.3
20
25
G20
ICD-10 Finland
Parkinson disease
3.5
9.3
41
117
SPAT1033
SPAT
Irrigation or wax removal of outer auditory canal
1.6
9.3
232
1490
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
2.0
9.2
121
631
SPAT1249
SPAT
Treatment-related counselling outside office
1.3
9.2
795
6530
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.5
9.1
322
2245
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.4
9.1
699
5634
SDA02
NOMESCO Finland
Parodonthologic therapy
1.4
9.0
625
4952
WX002
NOMESCO Finland
Sedation and analgesia
1.5
9.0
284
1931
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.7
9.0
188
1149
F72.0
ICD-10 Finland
Severe mental retardation, with the statement of no, or minimal, impairment of behaviour
24.1
8.9
12
5
CA1CM
NOMESCO Finland
Eye and orbita extensive MRI examination with 3 Tesla magnet
24.1
8.9
12
5
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.3
8.8
998
8515
SPAT1260
SPAT
Consultation of another employee
1.5
8.8
318
2230
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
1.8
8.8
161
947
G40.10
ICD-10 Finland
Simple partial seizures
4.5
8.6
29
65
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.8
8.6
145
826
WX882
NOMESCO Finland
High dependency care
2.1
8.6
93
452
G40.12
ICD-10 Finland
Simple partial seizures with secondary generalization
4.0
8.5
32
80
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.9
8.5
130
720
RS142
NOMESCO Finland
NA
9.0
8.5
17
19
H53.4
ICD-10 Finland
Visual field defects
3.7
8.5
35
95
N05AF03
ATC
chlorprothixene; systemic
2.7
8.5
54
200
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.5
8.4
277
1901
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.5
8.4
268
1826
H47.2
ICD-10 Finland
Optic atrophy
7.9
8.4
18
23
3508
FHL
Transposition or anteposition
+∞
8.3
8
*
H50.5
ICD-10 Finland
Heterophoria
+∞
8.3
8
*
CEC40
NOMESCO Finland
Resection and advancement of extraocular muscle
+∞
8.3
8
*
K02.1
ICD-10 Finland
Caries of dentine
1.3
8.3
1189
10449
WX402
NOMESCO Finland
General anaesthesia
1.5
8.3
311
2196
H54.7
ICD-10 Finland
Unspecified visual loss
6.2
8.3
21
34
N06AB06
ATC
sertraline; oral
1.6
8.3
222
1451
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
3.0
8.2
45
152
AA5HE
NOMESCO Finland
Brain ultrasound examination in a child
3.1
8.2
43
141
UDC00
NOMESCO Finland
Ear microscopy
1.8
8.2
138
788
K59.09
ICD-10 Finland
Constipation, unspecified
2.0
8.2
97
489
110
Kela drug reimbursment
Parkinson's disease and comparable movement disrorders
3.4
8.1
37
110
N28
ICPC
Limited function/disability (N)
4.8
8.1
25
52
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.5
8.0
260
1774
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
3.2
8.0
40
127
G80.0
ICD-10 Finland
Spastic quadriplegic cerebral palsy
22.1
8.0
11
5
N05AD01
ATC
haloperidol; systemic
2.8
8.0
49
179
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.5
8.0
301
2128
Z31.5
ICD-10 Finland
Genetic counselling
1.9
7.9
117
640
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.4
7.9
371
2735
P22.0
ICD-10 Finland
Respiratory distress syndrome of newborn
7.8
7.9
17
22
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
1.6
7.9
199
1280
SAA03
NOMESCO Finland
Extended examination of mouth
1.3
7.8
871
7371
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.6
7.8
209
1367
H52.4
ICD-10 Finland
Presbyopia
4.2
7.8
28
68
M79.1
ICD-10 Finland
Myalgia
1.6
7.8
224
1491
M01AX17
ATC
nimesulide; oral
1.5
7.8
257
1763
R26.8
ICD-10 Finland
Other and unspecified abnormalities of gait and mobility
3.6
7.7
33
93
L17
ICPC
Foot/toe symptom/complaint
1.4
7.7
432
3289
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
2.1
7.7
82
397
G03BA03
ATC
testosterone; systemic, rectal, sublingual, transdermal
2.3
7.6
64
278
NFL22
NOMESCO Finland
Myotomy or tenotomy of hip or thigh
18.4
7.6
11
6
Z63.7
ICD-10 Finland
Other stressful life events affecting family and household
2.3
7.6
68
303
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
1.8
7.6
127
727
S18
ICPC
Laceration/cut
1.3
7.6
640
5203
N03AX22
ATC
perampanel; oral
8.9
7.5
15
17
F05
ICPC
Visual disturbance other
2.6
7.5
50
192
G04BD12
ATC
mirabegron; oral
1.9
7.4
107
580
XKC03
NOMESCO Finland
Water cystometry
2.6
7.4
51
198
AAF05
NOMESCO Finland
Ventriculoperitoneal shunt
5.6
7.4
20
36
H60.8
ICD-10 Finland
Other otitis externa
2.6
7.3
51
199
TPH07
NOMESCO Finland
Cathetrisation of artery
1.7
7.3
144
865
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.7
7.3
137
810
N03AG04
ATC
vigabatrin; oral
8.4
7.3
15
18
3671A
ICD-9 Finland
Disorders of refraction and accommodation, Myopia
+∞
7.3
7
*
J45.9
ICD-10 Finland
Asthma, unspecified
1.5
7.3
294
2105
N05AN01
ATC
lithium; oral
2.6
7.3
49
190
AA7AA
NOMESCO Finland
Liquor cerebri shunt X-ray examinatin without contrast
9.4
7.3
14
15
H54.5
ICD-10 Finland
Severe visual impairment, monocular
9.4
7.3
14
15
G91.0
ICD-10 Finland
Communicating hydrocephalus
9.4
7.3
14
15
SPAT1254
SPAT
Administration of medicine
1.4
7.2
303
2188
T36
ICD-10 Finland
Poisoning by systemic antibiotics
1.9
7.2
102
552
F80.1
ICD-10 Finland
Expressive language disorder
2.9
7.2
42
148
G81.9
ICD-10 Finland
Hemiplegia, unspecified
5.4
7.2
20
37
N39.4
ICD-10 Finland
Other specified urinary incontinence
2.0
7.2
91
470
37720
ICD-8 Finland
Other diseases of retina and optic nerve, Amblyopia
30.1
7.1
9
*
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.3
7.1
820
6943
N04BD01
ATC
selegiline; oral
4.8
7.1
22
46
N06AX12
ATC
bupropion; oral
1.7
7.1
137
816
H57.1
ICD-10 Finland
Ocular pain
2.2
7.1
65
294
AAF25
NOMESCO Finland
Removal of shunt of ventricle of brain
12.0
7.1
12
10
G40.4
ICD-10 Finland
Other generalized epilepsy and epileptic syndromes
6.0
7.1
18
30
R39.1
ICD-10 Finland
Other difficulties with micturition
2.8
7.1
42
151
R4110
NOMESCO Finland
Physiotherapy
1.4
7.0
422
3247
F70.9
ICD-10 Finland
Mild mental retardation, Without mention of impairment of behaviour
8.8
7.0
14
16
181
Kela drug reimbursment
Retigabine and vigabatrin
8.8
7.0
14
16
Q53.2
ICD-10 Finland
Undescended testicle, bilateral
10.0
7.0
13
13
Q21.11
ICD-10 Finland
Paten or persistent foramen ovale
4.3
7.0
24
56
N04BC04
ATC
ropinirole; oral
4.7
7.0
22
47
Q21.10
ICD-10 Finland
Persistent ostium secundum
3.2
7.0
34
107
A01
ICPC
Pain general/multiple sites
1.8
7.0
124
724
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.3
7.0
539
4318
R62.8
ICD-10 Finland
Other lack of expected normal physiological development
4.0
7.0
26
66
N06BA04
ATC
methylphenidate; oral
1.9
6.9
91
477
SAA01
NOMESCO Finland
Simple examination of mouth
1.3
6.9
1472
13461
N06CA01
ATC
amitriptyline and psycholeptics; systemic
1.7
6.9
125
732
R11
ICD-10 Finland
Nausea and vomiting
1.6
6.9
160
1009
RT160
NOMESCO Finland
NA
4.6
6.9
22
48
P07.2
ICD-10 Finland
Extreme immaturity
13.8
6.9
11
8
RL130
NOMESCO Finland
NA
4.4
6.8
23
53
NA7CG
NOMESCO Finland
Spine and spinal cord extensive MRI examination with high intensity magnet
3.2
6.8
33
104
S01FA01
ATC
atropine; ophthalmic
11.0
6.8
12
11
K59.0
ICD-10 Finland
Constipation
1.9
6.8
90
476
XX4AW
NOMESCO Finland
NA
3.6
6.8
28
78
H54.2
ICD-10 Finland
Moderate visual impairment, binocular
5.3
6.8
19
36
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.6
6.8
160
1015
F79
ICD-10 Finland
Unspecified mental retardation
16.7
6.7
10
6
H60.9
ICD-10 Finland
Otitis externa, unspecified
1.7
6.7
123
724
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
2.0
6.7
79
399
R52.2
ICD-10 Finland
Other chronic pain
2.4
6.7
51
211
M25.5
ICD-10 Finland
Pain in joint
1.3
6.7
450
3525
N06AA10
ATC
nortriptyline; systemic
2.9
6.7
37
128
H47.7
ICD-10 Finland
Disorder of visual pathways, unspecified
22.6
6.7
9
*
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.3
6.6
1066
9390
E30.09
ICD-10 Finland
Delayed puberty NOS
7.8
6.6
14
18
N03AX18
ATC
lacosamide; systemic
4.2
6.6
23
55
101
Kela drug reimbursment
Anterior pituitary hypofunction
3.5
6.6
28
80
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
2.1
6.6
69
333
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
2.0
6.5
78
398
TNX33
NOMESCO Finland
Custom moulded cast, unspecified region
1.9
6.5
84
442
NK6MA
NOMESCO Finland
Measurement of bone age from hand and elbow using X-ray
2.2
6.5
64
302
G40.89
ICD-10 Finland
Other epilepsy
5.0
6.5
19
38
R13
ICD-10 Finland
Dysphagia
2.0
6.5
77
391
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
1.9
6.5
88
472
M54.5
ICD-10 Finland
Low back pain
1.3
6.4
531
4287
N31.0
ICD-10 Finland
Uninhibited neuropathic bladder, not elsewhere classified
7.4
6.4
14
19
NA1AD
NOMESCO Finland
Cervical spine CT examination
2.2
6.4
63
297
Q25.0
ICD-10 Finland
Patent ductus arteriosus
3.9
6.4
24
62
SPAT1234
SPAT
Support of social functional capacity
2.1
6.4
70
346
WX704
NOMESCO Finland
Intubation
1.8
6.3
109
630
NA1CG
NOMESCO Finland
Cervical spine extensive MRI examination with high intensity magnet
3.2
6.3
31
99
NF1DA
NOMESCO Finland
X-ray of hips
3.2
6.3
31
99
SPAT1053
SPAT
Memory test
1.7
6.3
116
684
H06.2*E05.9
ICD-10 Finland
Dysthyroid exophthalmos
8.2
6.3
13
16
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.4
6.3
275
1999
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.3
6.3
665
5546
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
1.8
6.3
96
535
F29
ICD-10 Finland
Unspecified nonorganic psychosis
1.9
6.3
88
476
H35.39
ICD-10 Finland
Degeneration of macula and posterior pole
3.3
6.3
29
89
XCW11
NOMESCO Finland
Assessment of strabismus
+∞
6.2
6
*
CEC90
NOMESCO Finland
Total transposition of extraocular muscle or muscles
+∞
6.2
6
*
N02AA05
ATC
oxycodone; systemic
1.6
6.2
140
878
H02AB09
ATC
hydrocortisone; systemic
2.2
6.2
61
286
G43.3
ICD-10 Finland
Complicated migraine
2.9
6.2
34
118
EBA05
NOMESCO Finland
Complicated extraction of tooth
1.4
6.2
285
2093
F45.4
ICD-10 Finland
Persistent somatoform pain disorder
3.2
6.2
29
90
K04.5
ICD-10 Finland
Chronic apical periodontitis
1.4
6.2
334
2522
KAT00
NOMESCO Finland
Extracorporeal shock wave lithotripsy of pelvis of kidney
5.3
6.1
17
32
R1210
NOMESCO Finland
Medical assessment of need and possibilities to rehabilitation
3.2
6.1
30
96
EBA15
NOMESCO Finland
Extraction of large number of teeth
2.2
6.1
56
255
NJ3CG
NOMESCO Finland
Extensive MRI examination of extremities with median high magnet
7.7
6.1
13
17
P20
ICPC
Memory disturbance
1.8
6.1
94
523
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
2.6
6.1
40
153
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
1.7
6.1
129
793
TJD20
NOMESCO Finland
Change of gastrostomy tube
4.7
6.1
19
41
E0000UV
ATC
NA
1.3
6.1
757
6443
G40.19
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
4.0
6.1
22
55
N05CF02
ATC
zolpidem; oral
1.5
6.1
242
1726
JDB10
NOMESCO Finland
Percutaneous gastrostomy
3.9
6.1
23
60
XJH00
NOMESCO Finland
Transanal ultrasonography
2.3
6.1
53
237
M03BX02
ATC
tizanidine; oral
1.3
6.1
954
8354
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
1.8
6.1
92
512
-
ICD-10 Finland
NA
2.9
6.1
33
114
U04
ICPC
Incontinence urine
2.2
6.0
55
250

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
73
94
7.97
53.29
1.2
1.1
0.5
4.0
nmol/l
—
9
18
1096
8136
1.63
29.57
8.5
7.0
1.2
1.2
mmol/l
0.56
922
6999
1010
7416
1.62
28.03
8.9
6.9
1.2
1.2
mmol/l
0.97
923
6832
651
4350
1.68
25.86
2.5
2.1
210.9
222.1
u/l
0.08
611
4133
99
314
3.24
25.12
5.2
5.2
410.1
376.0
umol/l
1.00
93
282
1295
10318
1.54
23.77
6.3
4.8
6.3
6.4
mmol/l
0.30
1217
9394
715
5131
1.56
20.29
2.8
2.5
51.8
55.7
u/l
2.57
656
4767
1542
13055
1.49
19.13
7.3
6.6
83.1
81.2
u/l
0.65
1440
12308
2083
18920
1.68
18.09
16.4
11.9
139.7
139.5
mmol/l
3.24
2029
18350
2083
18954
1.67
17.55
16.4
12.0
3.9
3.9
mmol/l
0.47
2027
18326
1770
15542
1.50
17.30
4.7
3.9
14.6
14.5
pmol/l
1.40
1626
14314
707
5222
1.50
16.96
3.6
3.0
37.0
45.5
ng/l
0.26
403
2842
373
2382
1.67
16.84
1.7
1.6
1241.2
1176.7
nmol/l
0.70
284
1834
873
6762
1.45
16.30
5.1
5.1
36.4
36.7
g/l
0.90
807
6307
713
5337
1.47
15.79
2.8
3.0
2.4
2.4
mmol/l
0.51
616
4776
959
7623
1.42
15.28
2.8
2.4
71.0
72.8
nmol/l
1.28
874
7087
705
5298
1.46
15.19
3.4
2.5
—
—
—
0
0
1032
8346
1.41
14.75
5.8
5.9
11.3
12.0
umol/l
0.72
957
7843
1979
17982
1.53
14.65
5.4
4.5
1.8
1.9
mu/l
0.55
1847
16874
348
2273
1.62
14.23
2.0
1.6
—
—
—
0
0
443
3080
1.53
13.79
1.6
1.6
35106846.5
32239008.1
pmol/l
0.04
376
2649
541
3938
1.48
13.48
4.1
4.0
—
—
—
0
0
668
5073
1.44
13.29
4.6
3.5
0.0
0.0
estimate
1.49
253
1843
729
5640
1.42
13.04
7.9
6.8
1.2
1.1
inr
0.10
223
1765
219
1303
1.75
12.71
5.2
4.6
0.1
0.4
%
0.54
53
296
214
1268
1.75
12.60
12.1
9.2
96.0
96.0
%
0.01
209
1224
51
168
3.08
12.28
13.4
13.8
825.2
800.0
nmol/l
0.14
51
162
54
184
2.98
12.27
1.7
1.5
—
—
—
0
0
529
3897
1.46
12.25
3.5
3.2
—
—
—
0
0
451
3222
1.49
12.21
3.3
3.3
1074.3
1086.8
ng/l
0.02
373
2658
596
4497
1.43
12.12
4.5
3.7
7.4
7.4
ph
0.09
128
857
770
6115
1.38
11.50
1.9
1.8
98.0
96.7
pmol/l
0.35
408
3298
1180
10014
1.34
11.45
7.3
6.5
0.0
0.0
e9/l
0.38
1047
8656
471
3435
1.46
11.41
1.5
1.5
20.5
20.3
nmol/l
0.10
403
3023
230
1429
1.67
11.39
5.2
4.4
1.5
0.9
%
0.83
62
376
1465
12850
1.35
11.35
5.2
4.0
1488.3
1892.2
e6/l
0.15
23
142
2175
20426
1.58
11.34
10.4
8.6
26.4
25.7
u/l
0.76
2104
19765
1143
9669
1.34
11.27
4.1
3.3
0.0
0.0
estimate
0.80
256
1839
137
734
1.92
11.18
7.2
7.3
24.5
24.2
mmol/l
0.26
128
684
231
1446
1.66
11.11
11.4
8.6
5.1
5.1
kpa
0.22
223
1378
231
1446
1.66
11.11
11.4
8.6
12.9
13.2
kpa
0.22
226
1381
1134
9596
1.34
11.09
4.1
3.2
0.0
0.0
estimate
1.08
247
1841
220
1366
1.67
10.91
5.3
4.5
0.2
0.1
%
0.26
59
349
563
4282
1.41
10.77
4.0
3.4
1.0
1.0
kg/l
0.65
88
666
342
2364
1.52
10.77
8.7
7.3
1.1
1.1
mmol/l
0.83
321
2222
2215
20934
1.61
10.73
13.9
10.0
—
—
—
0
0
1207
10341
1.33
10.69
8.0
6.9
0.2
0.2
e9/l
0.30
1081
9107
1171
9990
1.33
10.68
7.3
6.5
0.6
0.6
e9/l
0.87
1039
8631
1305
11309
1.33
10.67
10.5
9.0
4.1
3.9
e9/l
2.70
1153
9814
1212
10393
1.33
10.66
7.2
6.5
2.1
2.1
e9/l
0.41
1085
9198
2157
20273
1.54
10.59
15.0
11.7
69.9
70.0
umol/l
0.05
2157
20265
292
1958
1.56
10.55
2.4
2.2
348.3
374.9
nmol/l
1.51
267
1816
1533
13612
1.34
10.52
4.4
3.8
9.6
9.6
mm/h
0.01
1421
12702
211
1309
1.67
10.50
4.3
4.2
1.1
0.6
%
1.14
49
283
228
1443
1.64
10.50
11.6
8.6
1.2
0.9
mmol/l
0.61
174
1112
28
70
4.03
10.22
2.1
2.4
20.2
16.1
umol/l
0.90
28
70
1125
9596
1.32
10.05
5.4
4.5
0.0
0.0
estimate
0.50
261
1901
205
1281
1.65
9.92
7.0
6.3
—
—
—
0
0
1834
16800
1.37
9.80
4.1
3.5
5.7
5.7
mmol/l
0.43
1689
15548
244
1597
1.59
9.78
6.9
5.9
7.4
7.4
ph
0.23
26
130
1506
13409
1.32
9.73
4.8
3.9
—
—
—
0
0
245
1608
1.58
9.71
6.9
5.9
5.1
5.1
kpa
0.48
234
1529
356
2542
1.47
9.50
6.2
5.3
0.8
0.8
mmol/l
0.32
332
2404
189
1173
1.66
9.40
13.1
9.1
123.9
122.0
g/l
0.58
184
1131
819
6738
1.32
9.24
7.2
6.8
—
—
—
0
0
262
1771
1.54
9.11
9.5
7.4
104.8
104.6
mmol/l
0.35
256
1738
93
469
2.02
9.08
1.5
2.5
—
—
—
0
0
2121
19997
1.46
8.89
14.6
11.1
20.4
21.6
mg/l
0.93
1668
15097
195
1243
1.62
8.73
6.8
6.4
24.3
24.2
mmol/l
0.14
185
1209
1664
15164
1.30
8.29
5.1
4.4
38.3
38.0
mmol/mol
0.46
1545
14288
1268
11161
1.28
8.29
3.5
3.1
—
—
—
0
0
534
4214
1.34
7.82
1.7
1.6
1.4
1.3
mmol/l
0.34
462
3683
459
3546
1.36
7.72
3.5
2.7
548.6
558.3
mosm/kgh2o
0.40
400
3044
584
4689
1.32
7.56
2.2
2.4
2.8
2.8
mg/l
0.22
497
4058
184
1202
1.57
7.45
5.1
3.8
1.2
1.2
mmol/l
0.14
159
1039
127
763
1.70
7.18
6.1
5.2
—
—
—
0
0
296
2149
1.43
7.17
1.3
1.2
—
—
—
0
0
48
205
2.37
7.13
1.1
1.1
38.7
34.8
mg/l
0.22
42
162
93
511
1.85
7.13
5.4
5.2
—
—
—
0
0
47
199
2.39
7.12
1.1
1.1
223.7
226.8
mg/l
0.03
42
171
32
112
2.88
7.05
2.7
3.1
2.8
2.5
mmol/l
0.35
32
107
2348
22789
1.76
6.96
21.6
16.2
89.5
89.3
fl
1.12
2316
22497
2346
22766
1.75
6.94
21.7
16.3
259.5
260.5
e9/l
0.32
2293
22129
2348
22792
1.75
6.92
21.6
16.2
29.9
29.9
pg
0.48
2316
22499
228
1586
1.48
6.91
3.2
3.0
10.2
10.1
g/l
0.22
210
1470
2349
22805
1.76
6.91
21.9
16.4
135.1
135.2
g/l
0.02
2316
22512
227
1578
1.48
6.90
2.5
3.0
0.2
0.2
g/l
0.07
211
1500
2349
22806
1.76
6.89
21.8
16.3
6.9
6.8
e9/l
1.28
2289
22125
2348
22796
1.75
6.86
21.7
16.2
4.5
4.5
e12/l
0.05
2285
22114
221
1531
1.49
6.84
10.5
9.3
6.9
7.3
mmol/l
0.55
215
1481
79
418
1.92
6.81
7.3
6.5
1.3
1.2
mmol/l
0.11
71
358
92
512
1.83
6.78
1.4
2.4
17.8
13.9
e6/l
0.12
76
389
92
512
1.83
6.78
1.4
2.5
1073.1
708.5
e6/l
0.18
78
404
470
3712
1.33
6.75
3.4
2.5
6.6
7.5
e6/l
0.50
414
3269
1049
9178
1.25
6.65
7.9
6.7
0.6
0.7
%
0.70
1002
8647
89
494
1.83
6.63
2.3
2.5
247.3
350.4
ug/l
0.49
78
460
182
1225
1.52
6.47
3.6
3.3
—
—
—
0
0
1438
13054
1.25
6.46
3.5
3.0
41.9
36.9
u/l
0.87
1356
12437
1078
9485
1.24
6.43
7.7
6.6
2.7
2.9
%
1.96
1028
8912
1085
9556
1.24
6.40
8.1
6.7
8.3
8.2
%
0.06
1041
9032
131
822
1.63
6.31
3.1
2.9
—
—
—
0
0
169
1126
1.54
6.30
1.3
1.4
—
—
—
0
0
1113
9845
1.24
6.27
7.2
6.3
55.2
54.8
%
0.45
1059
9329
75
402
1.89
6.25
2.1
3.1
31.2
33.2
umol/l
0.41
66
354
344
2624
1.36
6.20
2.9
2.4
13.6
14.0
umol/l
0.49
310
2446
402
3158
1.33
5.95
1.3
1.2
18.4
28.5
iu/ml
1.73
120
909
350
2704
1.34
5.80
1.4
1.4
395.9
505.8
titre
1.07
58
507
185
1281
1.48
5.76
3.6
2.9
—
—
—
0
0
149
986
1.54
5.75
2.0
2.7
66.4
66.7
g/l
0.22
138
916
193
1351
1.46
5.69
2.6
2.1
10.3
11.4
nmol/l
0.99
165
1173
191
1336
1.47
5.66
4.1
3.6
—
—
—
0
0
242
1769
1.41
5.65
12.8
9.3
—
—
—
0
0
546
4499
1.27
5.61
3.8
3.2
—
—
—
0
0
1121
9999
1.22
5.61
7.6
6.5
30.5
30.7
%
0.29
1067
9441
647
5442
1.26
5.59
4.1
3.2
30.8
65.7
e6/l
1.51
517
4082
61
319
1.94
5.51
3.2
2.4
17.1
16.8
%
0.29
32
166
465
3777
1.29
5.34
2.6
2.7
1079.7
4611.8
umol/l
3.31
390
3370
16
44
3.65
5.20
2.2
2.8
—
—
—
0
0
65
356
1.85
5.13
3.7
4.0
3.9
3.8
mmol/l
0.22
60
331
782
6780
1.23
5.02
1.8
1.9
—
—
—
0
0
170
1191
1.46
5.02
5.6
5.0
78.6
71.8
ng/l
0.41
154
1084
146
993
1.50
5.00
2.3
2.3
8.9
6.7
ug/l
0.30
120
878
176
1243
1.45
4.98
2.8
3.2
69.2
70.6
e9/l
0.21
125
892
596
5024
1.25
4.98
3.9
3.1
0.2
0.4
e6/l
2.96
470
3716
285
2191
1.34
4.87
3.1
2.5
21.7
23.2
%
1.20
237
1921
110
710
1.57
4.79
18.2
11.4
—
—
—
0
0
306
2384
1.32
4.78
3.0
2.4
2.5
2.4
g/l
0.04
273
2216
64
358
1.81
4.74
7.9
4.4
2.1
2.2
mmol/l
0.12
45
220
594
5035
1.24
4.68
3.9
3.0
—
—
—
0
0
73
427
1.73
4.66
7.4
4.0
7.4
7.4
ph
1.52
62
353
323
2550
1.31
4.59
2.7
3.3
29.7
29.8
s
0.24
307
2478
153
1072
1.46
4.54
8.3
6.7
9.3
9.5
kpa
0.62
145
1021
769
6713
1.21
4.52
4.8
3.6
93.5
76.4
e6/l
0.17
555
4425
63
357
1.78
4.49
6.5
3.5
—
—
—
0
0
323
2558
1.30
4.48
2.5
2.6
2.4
2.4
mmol/l
0.02
271
2225
180
1303
1.41
4.48
3.5
3.2
4.7
4.7
pmol/l
0.11
161
1158
636
5456
1.22
4.45
3.8
2.8
—
—
—
0
0
50
265
1.90
4.41
2.7
2.7
1.2
1.4
e9/l
0.51
33
168
45
230
1.97
4.40
4.1
3.4
1.8
1.2
%
0.39
34
187
369
2980
1.28
4.40
1.3
1.2
6.2
11.1
u/ml
1.24
155
1167
1107
10013
1.19
4.40
3.1
2.9
80.8
79.4
ug/l
0.13
1035
9432
359
2895
1.28
4.33
5.0
4.3
2.4
2.2
ug/l
0.17
321
2622
1847
17513
1.22
4.32
4.2
3.8
2.8
2.8
mmol/l
0.37
1714
16404
22
83
2.66
4.32
1.3
1.3
—
—
—
0
0
49
260
1.90
4.31
1.4
2.6
—
—
—
0
0
18
61
2.96
4.28
2.9
2.4
—
—
—
0
0
545
4619
1.23
4.26
5.8
4.2
—
—
—
0
0
254
1959
1.33
4.26
7.5
6.2
1.6
1.6
mmol/l
0.01
205
1540
72
431
1.69
4.26
2.2
1.6
—
—
—
0
0
1830
17355
1.22
4.18
4.0
3.5
4.6
4.6
mmol/l
0.52
1713
16383
672
5829
1.21
4.16
2.7
2.3
—
—
—
0
0
24
97
2.49
4.13
1.3
1.3
—
—
—
0
0
183
1352
1.38
4.06
2.4
2.3
23.3
20.6
au/ml
—
9
100
36
175
2.07
4.06
1.2
1.2
—
—
—
0
0
78
484
1.63
4.04
1.4
1.4
299.6
323.6
ug/g
0.43
39
262
580
4975
1.22
4.01
3.6
3.5
7.4
8.1
mmol/l
2.65
498
4351
197
1476
1.36
4.01
18.5
19.1
1.3
1.2
inr
0.58
29
214
71
431
1.67
4.01
6.2
3.7
23.7
24.2
mmol/l
0.59
66
385
526
4468
1.23
4.01
4.5
4.7
90.3
91.9
%
0.88
510
4356
257
2006
1.31
3.97
1.4
1.5
—
—
—
0
0
40
205
1.97
3.92
1.1
1.1
—
—
—
0
0
62
368
1.70
3.82
2.4
2.3
132.1
132.5
g/l
0.06
51
287
191
1436
1.36
3.82
12.9
8.5
1.3
1.4
mmol/l
0.50
182
1352
1813
17233
1.20
3.78
4.0
3.5
1.4
1.5
mmol/l
3.60
1692
16208
43
230
1.88
3.74
2.7
2.7
12.2
10.4
%
0.47
25
171
988
8941
1.18
3.70
4.3
4.0
—
—
—
0
0
51
293
1.76
3.54
7.3
3.5
—
—
—
0
0
290
2348
1.27
3.40
2.1
1.9
—
—
—
0
0
1004
9143
1.17
3.39
11.1
9.0
0.0
0.0
e9/l
0.26
857
7381
104
720
1.46
3.36
17.6
11.2
24.3
24.2
mmol/l
0.08
95
688
223
1751
1.30
3.33
5.4
3.4
—
—
—
0
0
578
5037
1.19
3.32
7.0
7.2
—
—
—
0
0
82
542
1.53
3.31
2.1
2.0
4.4
4.3
iu/l
0.03
40
208
1737
16526
1.18
3.25
3.6
3.2
1.3
1.2
mmol/l
2.17
1608
15506
36
196
1.85
3.02
2.6
2.1
—
—
—
0
0
32
168
1.92
2.99
2.8
4.0
—
—
—
0
0
250
2021
1.26
2.98
3.2
3.9
5.8
6.8
umol/l
0.82
208
1707
38
212
1.80
2.96
2.7
3.9
—
—
—
0
0
56
349
1.62
2.94
1.5
1.6
—
—
—
0
0
512
4466
1.18
2.88
2.8
2.3
—
—
—
0
0
71
472
1.52
2.84
2.4
1.9
2.2
2.3
ug/l
0.01
59
415
33
578
0.56
2.77
1.1
1.1
17.9
6.5
u/ml
0.38
13
275
134
1007
1.35
2.76
3.3
3.3
129.2
173.4
ng/l
0.85
120
903
102
733
1.41
2.75
2.0
2.2
—
—
—
0
0
39
225
1.74
2.74
2.3
2.7
445.8
522.7
e6/l
0.57
31
172
158
1218
1.32
2.74
2.0
1.8
1.2
1.3
g/l
0.68
149
1138
175
1370
1.30
2.71
1.9
1.5
17.7
18.5
iu/l
0.16
136
1080
41
241
1.71
2.70
2.6
2.8
46.4
41.4
%
—
7
14
353
2998
1.21
2.67
3.1
2.7
1.0
1.2
e6/l
0.51
207
1640
103
746
1.40
2.67
1.1
1.1
—
—
—
0
0
342
2900
1.21
2.63
3.4
2.9
3.9
3.0
e6/l
0.90
195
1541
38
221
1.73
2.61
2.3
2.7
0.2
0.2
e9/l
0.39
32
172
202
1629
1.26
2.49
1.4
1.3
201.4
243.1
u/ml
0.37
179
1513
50
765
0.65
2.46
1.1
1.1
7.1
3.4
u/ml
0.54
14
241
219
1787
1.25
2.45
3.3
3.7
1.7
1.6
%
0.19
200
1618
56
367
1.54
2.43
5.5
3.9
55.0
55.9
%
0.18
56
367
1844
17762
1.15
2.43
17.9
13.8
13.5
13.4
%
0.90
1815
17403
103
761
1.37
2.40
14.7
11.8
1.2
1.2
mg/l
0.17
93
728
325
2768
1.20
2.39
3.4
3.4
281.1
484.9
ng/l
1.45
205
1770
181
1449
1.27
2.39
1.2
1.2
116.9
122.5
titre
—
8
42
28
489
0.57
2.37
1.0
1.1
0.1
0.4
u/ml
—
8
164
153
1201
1.29
2.36
1.2
1.2
—
—
—
0
0
45
283
1.60
2.34
2.7
3.6
38.7
31.3
mg/l
0.24
31
225
45
283
1.60
2.34
2.7
3.6
44.8
70.4
mg/l
0.49
31
225
207
1688
1.25
2.34
3.1
2.7
1.0
0.7
ug/l
0.69
125
1006
176
1411
1.27
2.30
6.9
6.8
24.0
23.8
mmol/l
0.52
165
1326
10
35
2.86
2.30
1.2
1.6
—
—
—
0
0
27
148
1.83
2.28
2.2
3.4
—
—
—
0
0
32
185
1.74
2.28
1.2
1.4
1.4
0.8
u/ml
0.26
12
63
45
287
1.58
2.22
1.5
3.4
—
—
—
0
0
22
114
1.94
2.20
1.0
1.2
—
62.7
—
0
13
83
1129
0.73
2.20
1.5
1.5
—
—
—
0
0
171
1376
1.26
2.18
1.8
1.6
367.7
310.7
mu/l
0.80
156
1236
81
1102
0.73
2.15
1.5
1.5
—
—
—
0
0
45
290
1.56
2.14
1.6
1.4
—
—
—
0
0
204
2459
0.81
2.12
1.2
1.3
—
—
—
0
0
136
1068
1.29
2.12
2.2
1.6
5.7
8.0
u/l
3.04
106
807
33
534
0.61
2.11
1.1
1.1
25.3
7.1
u/ml
0.47
13
274
133
1044
1.29
2.08
1.5
1.4
—
—
—
0
0
105
1366
0.76
2.08
1.4
1.4
—
—
—
0
0
5
10
5.01
2.07
1.8
2.5
—
—
—
0
0
53
358
1.49
2.05
4.8
3.6
4.0
4.0
e9/l
0.03
53
358
24
132
1.83
2.03
2.7
2.9
66.0
52.5
%
2.28
15
89
12
50
2.41
2.02
2.0
2.3
—
—
—
0
0
8
26
3.08
2.01
10.0
8.0
—
—
—
0
0
99
1290
0.76
1.99
1.6
1.6
—
—
—
0
0
82
1098
0.74
1.99
1.5
1.5
—
—
—
0
0
14
64
2.19
1.94
1.9
2.7
—
—
—
0
0
233
1966
1.20
1.93
2.7
2.3
6018.8
6813.7
u/l
0.14
92
777
157
1272
1.25
1.92
3.6
2.4
3.9
4.2
e9/l
1.08
117
1065
650
5933
1.13
1.92
1.5
1.4
1.3
1.9
u/ml
0.90
196
1442
30
180
1.67
1.91
1.1
1.3
—
—
—
0
0
242
2054
1.20
1.89
1.2
1.2
—
—
—
0
0
34
212
1.61
1.88
1.6
1.6
284.7
286.6
mosm/kgh2o
0.23
28
162
379
3342
1.16
1.86
1.8
1.6
—
—
—
0
0
39
253
1.55
1.84
1.4
1.9
74.4
70.4
mmol/l
0.22
32
219
10
40
2.51
1.83
2.3
1.4
—
—
—
0
0
12
53
2.27
1.80
1.4
3.2
—
—
—
0
0
7
23
3.05
1.80
1.4
1.3
—
—
—
0
0
29
176
1.66
1.79
1.4
1.4
1.2
1.3
promille
0.10
19
140
340
3856
0.86
1.78
1.4
1.6
—
—
—
0
0
34
521
0.65
1.76
1.2
1.1
—
—
—
0
0
179
1487
1.22
1.76
2.8
2.2
—
—
—
0
0
454
4074
1.14
1.75
2.2
2.2
1.1
1.2
mg/l
0.16
331
2960
42
281
1.50
1.74
4.6
2.9
—
—
—
0
0
55
766
0.71
1.74
1.1
1.1
0.8
1.3
u/ml
0.76
25
431
34
519
0.65
1.74
1.2
1.1
—
—
—
0
0
362
3201
1.15
1.72
2.2
2.7
138.8
112.1
ug/g
0.47
283
2526
65
474
1.38
1.72
1.5
1.3
—
—
—
0
0
68
500
1.37
1.71
1.2
1.6
55.0
76.4
titre
—
6
47
13
61
2.14
1.71
3.3
3.4
7.4
7.4
ph
—
6
17
25
148
1.70
1.70
2.2
1.8
15.2
23.8
umol/l
1.31
25
143
64
864
0.73
1.68
1.1
1.2
0.4
2.7
u/ml
5.49
32
463
150
1230
1.23
1.68
1.3
1.2
—
—
—
0
0
92
711
1.31
1.67
1.1
1.1
3.3
6.2
u/ml
0.72
13
104
64
470
1.37
1.64
1.1
1.2
5.7
3.1
u/ml
—
8
45
207
1758
1.19
1.63
1.3
1.3
—
—
—
0
0
31
197
1.58
1.62
1.5
1.2
—
—
nmol/l
—
0
0
567
5189
1.12
1.59
1.6
1.5
2.1
2.1
g/l
0.15
360
3096
93
726
1.29
1.58
4.2
4.5
0.2
0.3
g/l
0.73
47
397
51
363
1.41
1.57
6.9
7.2
—
—
—
0
0
22
130
1.70
1.53
1.0
1.1
—
—
—
0
0
205
1752
1.19
1.52
2.7
2.1
—
—
—
0
0
6
21
2.86
1.50
1.2
1.8
—
—
—
0
0
12
58
2.07
1.49
1.3
1.7
—
—
—
0
0
100
796
1.27
1.48
1.8
1.7
—
—
—
0
0
60
797
0.75
1.45
1.1
1.1
3.7
6.6
u/ml
1.11
30
510
219
1892
1.17
1.44
2.7
2.1
—
—
—
0
0
34
228
1.50
1.44
1.4
1.2
—
0.7
nmol/l
—
0
8
6
22
2.73
1.43
1.2
1.1
1.4
1.7
umol/24h
—
6
22
13
66
1.97
1.43
1.1
1.0
—
—
—
0
0
17
95
1.79
1.43
1.7
1.9
—
—
—
0
0
92
729
1.27
1.42
1.2
1.2
0.3
0.7
u/ml
—
10
53
427
4692
0.89
1.40
1.8
1.7
—
—
—
0
0
5
17
2.94
1.36
10.0
8.4
4.3
6.2
mmol/l
—
5
17
125
1499
0.82
1.32
1.3
1.3
—
—
—
0
0
25
160
1.57
1.31
1.2
1.2
—
—
—
0
0
6
24
2.50
1.30
1.5
1.5
—
—
—
0
0
40
284
1.41
1.29
2.0
1.7
—
—
—
0
0
40
284
1.41
1.29
2.0
1.7
—
—
—
0
0
40
284
1.41
1.29
2.0
1.7
—
—
—
0
0
40
284
1.41
1.29
2.0
1.7
—
—
—
0
0
9
175
0.51
1.28
1.1
1.4
—
—
—
0
0
13
230
0.56
1.27
3.0
3.8
25.3
23.4
u/ml
0.08
13
224
215
1877
1.16
1.26
2.6
2.1
—
—
—
0
0
216
1889
1.16
1.24
2.5
2.1
—
—
—
0
0
5
19
2.63
1.21
1.0
1.2
—
8.9
—
0
6
26
173
1.51
1.17
1.2
1.1
—
—
—
0
0
24
157
1.53
1.17
1.2
1.2
—
—
—
0
0
17
102
1.67
1.16
6.4
3.4
99.3
146.5
umol/l
—
9
59
8
39
2.05
1.15
1.9
1.7
—
—
—
0
0
5
20
2.50
1.15
1.2
1.5
—
—
—
0
0
0
35
0.00
1.15
0.0
1.1
—
4.5
—
0
25
24
158
1.52
1.14
1.2
1.1
—
—
—
0
0
18
111
1.63
1.12
1.7
2.1
1.8
1.9
u/field
0.04
12
58
20
127
1.58
1.11
1.1
1.0
—
—
—
0
0
204
1795
1.15
1.10
1.2
1.2
106.7
146.0
iu/ml
0.88
78
658
30
209
1.44
1.10
1.3
1.2
—
—
—
0
0
108
902
1.21
1.09
1.9
2.5
34.7
43.0
u/ml
0.37
102
866
12
66
1.82
1.09
1.2
1.8
—
—
—
0
0
8
41
1.95
1.08
2.8
2.7
—
—
—
0
0
8
41
1.95
1.08
2.4
14.0
—
—
—
0
0
29
202
1.44
1.07
1.1
1.5
483.0
435.5
pmol/l
0.09
22
153
11
59
1.87
1.07
1.6
1.4
—
—
—
0
0
26
178
1.47
1.05
1.0
1.1
—
—
—
0
0
14
82
1.71
1.05
1.1
1.5
135.5
139.0
nmol/l
0.12
14
82
14
228
0.61
1.04
1.1
1.1
0.0
2.6
u/ml
—
5
48
49
376
1.31
1.03
1.2
1.1
—
—
—
0
0
66
527
1.26
1.02
2.7
3.3
—
—
—
0
0
5
109
0.46
1.00
1.0
1.0
—
6.3
—
0
14
9
48
1.88
1.00
4.9
6.5
—
—
—
0
0
7
35
2.00
1.00
2.6
1.0
—
—
—
0
0
85
701
1.22
1.00
2.3
2.3
—
—
—
0
0
16
99
1.62
0.99
2.6
2.3
—
—
—
0
0
15
92
1.63
0.97
1.0
1.0
—
10.2
—
0
20
114
974
1.18
0.93
1.1
1.1
—
—
—
0
0
208
1858
1.13
0.93
2.5
2.0
—
—
—
0
0
85
709
1.21
0.91
1.2
1.7
—
9.6
—
0
25
14
86
1.63
0.90
2.7
2.5
—
—
—
0
0
6
29
2.07
0.89
2.2
2.0
—
—
—
0
0
409
3799
1.09
0.88
4.0
4.1
13.9
11.1
mg/mmol
0.27
267
2497
129
1120
1.16
0.88
1.5
1.3
211.8
239.3
miu/ml
0.28
43
550
28
204
1.38
0.85
1.1
1.7
—
—
—
0
0
6
31
1.94
0.84
3.2
1.2
—
—
—
0
0
390
3627
1.09
0.83
3.2
3.4
713.3
329.9
mg/l
0.61
254
2402
6
32
1.88
0.81
1.3
1.3
67.8
55.2
%
—
6
22
50
400
1.25
0.81
1.6
1.4
22.2
17.3
u/l
0.45
39
348
183
1641
1.12
0.80
2.8
2.4
26.7
67.8
u/l
0.78
156
1378
8
48
1.67
0.78
3.4
2.2
—
—
—
0
0
71
593
1.20
0.78
1.6
1.7
—
—
—
0
0
75
632
1.19
0.76
1.6
1.6
0.2
0.2
g/l
0.45
69
596
51
413
1.24
0.75
1.1
1.0
3.4
3.2
u/ml
0.04
22
187
23
167
1.38
0.73
10.4
11.4
12.7
11.3
%
1.00
23
167
77
653
1.18
0.73
1.6
1.6
1.2
1.2
g/l
0.07
70
617
30
228
1.32
0.72
2.4
2.4
—
—
—
0
0
5
25
2.00
0.72
1.2
1.2
—
—
—
0
0
10
60
1.67
0.72
7.7
5.3
1.2
1.2
mmol/l
—
10
55
100
869
1.16
0.71
2.8
4.2
21.3
21.8
s
0.55
88
776
24
321
0.74
0.71
2.4
2.6
80.5
117.2
ug/min
0.29
13
209
69
582
1.19
0.70
1.7
2.0
1.4
1.4
g/l
0.18
61
515
9
142
0.63
0.69
1.2
1.2
—
—
—
0
0
26
195
1.34
0.69
3.0
4.4
—
—
—
0
0
75
640
1.18
0.68
1.2
1.2
—
—
—
0
0
26
196
1.33
0.67
1.7
2.0
—
—
—
0
0
26
196
1.33
0.67
1.7
2.5
888.5
806.0
e6/l
0.18
12
49
139
1243
1.13
0.66
1.5
1.5
—
—
—
0
0
5
28
1.79
0.66
1.8
1.1
8.4
33.4
%
—
5
22
30
233
1.29
0.64
1.4
1.4
6.2
6.5
g/l
0.24
18
167
22
164
1.34
0.62
2.6
2.9
263.8
303.9
e6/l
0.12
13
104
9
137
0.66
0.60
3.1
5.0
12.9
8.6
mg/l
—
9
120
9
141
0.64
0.60
1.0
1.1
—
—
—
0
0
17
122
1.40
0.60
1.8
3.1
77.1
16.6
mg/l
0.69
12
89
44
363
1.22
0.59
1.2
1.1
—
—
—
0
0
8
54
1.48
0.57
1.0
1.2
—
—
—
0
0
147
1334
1.11
0.57
1.4
1.4
—
—
—
0
0
18
132
1.37
0.57
1.2
1.2
1.1
1.1
ratio
—
5
56
46
383
1.20
0.57
1.6
2.5
—
—
—
0
0
66
568
1.17
0.56
1.7
1.7
112.2
99.7
u/ml
0.72
18
86
8
55
1.46
0.56
2.3
2.2
1.9
3.4
ug/l
—
8
50
21
274
0.76
0.56
1.1
1.3
2.3
3.8
u/ml
0.30
12
144
6
37
1.62
0.55
1.8
1.2
—
—
—
0
0
19
142
1.34
0.54
2.0
2.3
4.2
3.9
mmol/l
0.98
19
142
20
151
1.33
0.53
3.1
4.8
—
—
—
0
0
61
525
1.17
0.53
10.6
8.7
—
—
—
0
0
75
656
1.15
0.53
2.7
3.0
6.1
6.5
umol/l
0.13
54
521
6
99
0.60
0.52
1.2
1.1
—
—
—
0
0
23
179
1.29
0.51
1.0
1.0
—
—
—
0
0
25
197
1.27
0.51
9.0
4.7
6.4
6.5
mmol/l
0.08
20
161
29
233
1.25
0.51
1.4
1.4
0.5
0.4
g/l
0.50
19
164
29
233
1.25
0.51
1.4
1.4
2.6
2.6
g/l
0.00
19
166
29
233
1.25
0.51
1.2
1.2
—
—
—
0
0
15
109
1.38
0.50
1.1
1.2
—
—
—
0
0
123
1115
1.11
0.50
3.0
4.2
7.2
25.0
ug/l
1.25
90
867
163
1767
0.92
0.49
1.5
1.4
—
—
—
0
0
18
136
1.33
0.49
2.1
2.3
—
—
—
0
0
7
109
0.64
0.48
1.6
1.2
3.6
12.7
u/ml
—
7
96
29
235
1.24
0.48
1.4
1.4
—
—
—
0
0
128
1167
1.10
0.48
2.3
2.6
—
—
—
0
0
12
85
1.41
0.46
1.0
1.1
—
—
—
0
0
7
48
1.46
0.46
1.0
1.1
—
—
—
0
0
7
48
1.46
0.46
2.6
3.1
—
—
—
0
0
11
77
1.43
0.45
1.1
1.1
—
—
—
0
0
65
735
0.88
0.44
1.2
1.2
—
—
—
0
0
13
95
1.37
0.43
3.0
1.9
—
—
—
0
0
26
211
1.23
0.43
4.7
4.0
—
—
—
0
0
5
31
1.61
0.43
1.8
1.3
6.6
1.5
%
—
5
23
30
249
1.21
0.41
1.7
1.4
—
—
—
0
0
8
59
1.36
0.41
1.1
1.6
—
—
—
0
0
0
17
0.00
0.40
0.0
5.0
—
—
—
0
0
5
34
1.47
0.40
1.2
1.7
—
—
—
0
0
1990
19723
1.05
0.38
15.8
12.2
39.9
40.0
%
0.12
1475
16074
18
142
1.27
0.38
2.1
2.3
106.2
105.5
mmol/l
0.31
18
142
13
98
1.33
0.37
2.0
2.2
—
—
—
0
0
5
37
1.35
0.37
1.0
1.3
—
—
—
0
0
216
2041
1.06
0.36
1.6
1.5
—
—
—
0
0
31
364
0.85
0.36
1.7
1.7
—
—
—
0
0
38
438
0.87
0.35
1.2
1.2
—
—
—
0
0
12
90
1.33
0.35
1.8
1.4
71868.3
101139.3
e6/l
—
6
56
77
698
1.11
0.35
1.5
1.5
192.7
225.2
u/ml
0.75
48
393
1824
18412
0.96
0.35
18.1
14.0
333.5
333.5
g/l
0.01
1806
18255
41
357
1.15
0.35
1.4
1.7
0.5
0.8
g/l
1.84
29
271
10
134
0.75
0.35
1.8
1.4
3.7
6.3
ug/l
—
10
114
6
44
1.36
0.34
1.3
1.7
—
—
—
0
0
6
46
1.30
0.33
2.0
1.2
—
—
—
0
0
6
47
1.28
0.32
1.0
1.0
162.0
165.3
g/l
—
6
47
11
143
0.77
0.32
1.2
1.4
1.8
1.4
nmol/l
0.90
11
130
7
98
0.71
0.30
1.0
1.0
—
—
—
0
0
7
98
0.71
0.30
1.3
1.1
—
—
—
0
0
7
57
1.23
0.29
1.1
1.2
—
—
—
0
0
7
57
1.23
0.29
1.1
1.2
—
—
—
0
0
7
57
1.23
0.29
1.1
1.2
—
—
—
0
0
37
326
1.14
0.28
1.6
1.7
7438.3
13116.1
e6/l
1.19
32
246
674
6891
0.97
0.28
2.3
2.1
—
—
—
0
0
8
62
1.29
0.28
1.0
1.2
—
—
—
0
0
65
596
1.09
0.26
1.3
1.2
—
—
—
0
0
5
72
0.69
0.26
2.4
1.9
—
—
—
0
0
21
180
1.17
0.23
3.0
3.1
0.8
0.8
nmol/l
0.01
14
139
28
246
1.14
0.23
1.1
1.1
5.3
8.1
iu/ml
—
7
50
16
190
0.84
0.23
1.2
1.3
—
180.0
—
0
9
19
162
1.17
0.22
1.9
2.8
2.7
38.1
nmol/l
0.51
19
155
34
304
1.12
0.22
1.4
1.3
—
—
—
0
0
5
40
1.25
0.22
1.8
1.9
—
—
—
0
0
193
1853
1.04
0.22
1.4
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
0.1
—
0
5
0
11
0.00
0.21
0.0
1.0
—
0.2
—
0
6
36
325
1.11
0.21
1.1
1.1
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
71.6
—
0
13
0
13
0.00
0.21
0.0
1.2
—
33.9
—
0
13
0
13
0.00
0.21
0.0
1.3
—
—
—
0
0
0
14
0.00
0.20
0.0
1.0
—
9.0
—
0
5
37
336
1.10
0.19
2.3
2.0
40.4
38.0
g/l
1.36
30
298
28
250
1.12
0.19
1.6
1.7
—
—
—
0
0
35
384
0.91
0.18
1.4
1.1
151.1
158.6
iu/ml
—
10
117
70
657
1.07
0.18
1.1
1.2
—
—
—
0
0
12
100
1.20
0.18
1.8
1.4
1867.1
2148.9
e6/l
—
7
70
25
223
1.12
0.18
1.5
1.6
—
—
—
0
0
11
91
1.21
0.17
1.8
1.3
6.6
6.4
mmol/l
0.11
11
83
13
110
1.18
0.17
2.6
2.8
—
—
—
0
0
36
330
1.09
0.16
2.8
2.6
—
—
—
0
0
18
204
0.88
0.16
4.2
4.0
66.3
92.7
u/ml
—
6
61
42
452
0.93
0.15
1.1
1.2
—
—
—
0
0
6
77
0.78
0.15
1.3
2.3
—
209.7
—
0
10
6
79
0.76
0.15
1.3
1.1
—
4.4
iu/ml
—
0
7
35
323
1.08
0.14
1.2
1.2
—
—
—
0
0
48
512
0.94
0.14
1.4
1.5
0.5
0.5
nmol/l
0.04
35
426
16
181
0.88
0.14
1.2
1.4
—
—
—
0
0
8
97
0.82
0.13
7.6
6.8
—
—
—
0
0
13
149
0.87
0.13
1.3
1.7
—
—
—
0
0
36
335
1.08
0.13
2.8
3.6
—
—
—
0
0
244
2495
0.98
0.13
1.8
2.0
—
—
—
0
0
225
2197
1.03
0.12
1.2
1.2
—
—
—
0
0
27
248
1.09
0.12
1.7
1.5
—
—
—
0
0
41
385
1.07
0.12
1.4
1.3
—
—
—
0
0
15
133
1.13
0.12
2.0
1.4
—
—
—
0
0
13
114
1.14
0.11
37.2
32.4
123.9
142.9
ug/l
0.34
13
104
16
143
1.12
0.11
1.4
1.2
—
—
—
0
0
36
339
1.06
0.10
1.3
1.3
3.5
4.9
u/ml
0.52
17
150
38
359
1.06
0.09
1.1
1.1
—
—
—
0
0
18
164
1.10
0.09
1.0
1.0
—
—
—
0
0
39
369
1.06
0.09
2.9
3.0
21.5
25.1
mg/l
0.38
27
220
20
217
0.92
0.09
1.4
1.5
—
—
—
0
0
5
48
1.04
0.09
1.0
1.1
—
—
—
0
0
13
116
1.12
0.09
1.0
1.1
—
—
—
0
0
14
126
1.11
0.09
3.5
3.3
—
—
—
0
0
12
134
0.89
0.08
1.1
1.1
—
—
—
0
0
15
137
1.10
0.07
1.5
1.2
—
—
—
0
0
8
76
1.05
0.07
1.8
1.9
—
—
—
0
0
9
87
1.03
0.07
6.1
3.9
—
—
—
0
0
8
95
0.84
0.06
2.6
1.5
—
—
—
0
0
76
780
0.97
0.06
2.7
2.8
—
—
—
0
0
543
5467
0.99
0.06
1.9
1.7
—
—
—
0
0
15
161
0.93
0.05
1.1
1.1
—
—
—
0
0
41
423
0.97
0.04
1.9
1.8
—
—
—
0
0
11
119
0.92
0.04
1.3
1.1
—
—
—
0
0
674
6711
1.01
0.03
2.5
2.3
—
—
—
0
0
15
141
1.06
0.03
1.0
1.0
19.2
19.5
mmol/l
0.10
15
135
17
162
1.05
0.02
1.8
2.1
—
—
—
0
0
690
6915
1.00
0.02
1.7
1.7
—
—
—
0
0
14
133
1.05
0.01
1.0
1.0
—
—
—
0
0
10
106
0.94
0.01
1.4
1.1
227.8
206.3
iu/ml
—
10
106
13
127
1.02
0.00
1.0
1.1
1722.5
1416.8
miu/ml
0.45
13
127
12
124
0.97
0.00
1.5
1.6
0.1
11.6
u/ml
—
6
30
10
104
0.96
0.00
8.3
5.8
72.4
78.4
mg/l
—
10
87
76
765
0.99
0.00
1.7
1.6
—
—
—
0
0
15
148
1.01
0.00
1.0
1.1
249.6
297.1
mg/l
2.34
15
131
16
156
1.03
0.00
1.5
1.2
—
—
—
0
0
14
145
0.97
0.00
1.1
1.2
—
—
—
0
0
10
96
1.04
0.00
1.6
1.2
—
—
—
0
0
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
0.00
0.0
4.8
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
8
83
0.96
0.00
1.8
1.4
—
—
—
0
0
0
7
0.00
0.00
0.0
1.9
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
3.6
—
1.9
—
0
5
9
92
0.98
0.00
1.7
1.5
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
0.1
—
0
5
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
8
79
1.01
0.00
1.0
1.1
—
—
—
0
0
8
79
1.01
0.00
2.0
2.5
2006.3
2086.8
ml
—
8
74
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint H7_INTERHETEROTRO and mortality.

Females

Parameter HR [95% CI] p-value
H7_INTERHETEROTRO 1.207 [0.97, 1.5] 0.09
Birth year 0.999 [0.99, 1.01] 0.839

During the follow-up period (1.1.1998 — 31.12.2019), 413 out of 17721 females with H7_INTERHETEROTRO died.

Males

Parameter HR [95% CI] p-value
H7_INTERHETEROTRO 1.247 [1.01, 1.53] 0.036
Birth year 0.985 [0.98, 0.99] 0.002

During the follow-up period (1.1.1998 — 31.12.2019), 436 out of 15644 males with H7_INTERHETEROTRO died.

Mortality risk

Mortality risk for people of age

years, who have H7_INTERHETEROTRO.

N-year risk Females Males
1 0.137% 0.3%
5 0.895% 1.526%
10 2.02% 3.477%
15 3.824% 6.621%
20 6.883% 11.084%

Relationships between endpoints

Index endpoint: H7_INTERHETEROTRO – Intermittent heterotropia

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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