Risteys ·

OMOP concept ID	Test name	Measurement unit (harmonized unit)	N people	N records	Missing measurement value	Harmonized value distribution
3003888	s-timotee	u/ml (u/ml)	4424	4784	0.04%
3003888	s-timotee	— (—)	3698	3847	100.00%	Distribution not available
3003888	timotei	— (—)	523	544	100.00%	Distribution not available
3003888	timotei	u/ml (u/ml)	212	220	0.00%

LabWAS

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

Asthma (mode)

2485

2727

5.21

307.65

1.1

1.0

5.64

5.08

u/ml

0.63

1585

1141

Asthma (diagnoses ohter than nonallergic)

2576

5710

4.01

307.65

1.1

5.48

5.87

u/ml

0.49

1729

2666

Disorders of conjunctiva

1954

6279

2.67

307.65

1.1

6.96

5.29

u/ml

3.79

1335

3069

Other diseases of upper respiratory tract

2158

4147

2.76

307.65

1.1

1.0

6.29

5.00

u/ml

2.15

1298

1874

Atopic dermatitis

1743

4988

3.10

307.65

1.1

7.35

5.75

u/ml

2.80

1136

2502

Conjunctivitis

1912

6129

2.80

307.65

1.1

6.96

5.33

u/ml

3.58

1312

3006

Allergic conjunctivitis

1648

5176

3.25

307.65

1.1

7.19

5.46

u/ml

3.39

1163

2457

Use of eye-antiallergens (taken as indicator of allergic/atopic conjunctivitis)

1596

4897

3.33

307.65

1.1

7.22

5.38

u/ml

3.65

1130

2305

Asthma-related infections

1512

3909

3.94

307.65

1.1

5.76

6.06

u/ml

0.26

1032

1895

Asthma (only as main-diagnosis)

2354

2715

5.45

307.65

1.1

1.0

5.61

5.08

u/ml

0.58

1526

1137

Asthma/COPD (KELA code 203)

2552

5242

3.54

307.65

1.1

5.18

5.89

u/ml

1.11

1561

2501

Asthma

2486

2715

5.10

307.65

1.1

1.0

5.64

5.08

u/ml

0.62

1581

1137

1321

3307

4.14

307.65

1.2

1.1

5.73

6.32

u/ml

0.55

905

1645

Asthma, hospital admission 2, infections

1512

3909

3.94

307.65

1.1

5.76

6.06

u/ml

0.26

1032

1895

Asthma, excluding more controls

2475

2678

5.13

307.65

1.1

1.0

5.65

5.14

u/ml

0.54

1577

1121

Allergic rhinitis

2004

2943

7.55

307.65

1.2

1.1

7.81

5.53

u/ml

4.83

1459

1399

Asthma and allergy

981

1019

10.87

307.65

1.2

1.0

6.74

6.49

u/ml

0.13

782

461

Asthma and allergy, excluding more controls

982

1033

10.73

307.65

1.2

1.0

6.73

6.56

u/ml

0.08

783

472

Asthma, including avohilmo

3542

5023

4.25

307.65

1.1

5.55

5.86

u/ml

0.37

2138

2377

Asthma, hospital admissions , main diagnosis only

2502

5834

3.99

307.65

1.1

5.61

5.75

u/ml

0.14

1655

2770

Desensitization to allergens

513

656

9.75

307.65

1.1

10.04

7.17

u/ml

1.92

405

371

Vasomotor and allergic rhinitis

2090

3020

7.46

307.65

1.1

1.0

7.68

5.27

u/ml

5.85

1499

1426

Allergic asthma (mode), excluding more controls

1327

1656

8.59

307.65

1.2

1.0

5.96

6.00

u/ml

0.02

1026

735

Dermatitis and eczema

2315

6102

2.54

307.65

1.1

6.24

5.28

u/ml

1.68

1406

2989

Pollen allergy

1594

2097

8.89

307.65

1.2

1.1

8.24

5.76

u/ml

4.37

1203

1078

Chronic lower respiratory diseases

3239

5296

3.41

307.65

1.1

5.52

5.90

u/ml

0.50

1984

2525

Asthma (only as main-diagnosis), excluding more controls

2348

2678

5.45

307.65

1.1

1.0

5.63

5.14

u/ml

0.51

1522

1121

Allergic asthma (mode)

1327

1657

8.58

307.65

1.2

1.0

5.96

6.00

u/ml

0.02

1026

734

Asthma, unspecified (mode)

1038

2245

3.76

303.34

1.1

1.0

5.16

4.62

u/ml

0.36

577

921

Asthma, unspecified (mode), excluding more controls

1037

2221

3.76

302.36

1.1

1.0

5.17

4.67

u/ml

0.33

576

910

Atopic dermatitis, strict definition with reimbursement

1116

3316

3.43

293.21

1.2

1.1

7.77

6.44

u/ml

1.48

809

1726

Chronic rhinitis, nasopharyngitis and pharyngitis

779

1869

4.33

293.03

1.1

1.0

4.30

4.38

u/ml

0.05

446

846

Chronic sinusitis

922

2499

3.80

291.60

1.1

1.0

3.47

4.33

u/ml

1.21

533

1082

Suggestive for eosinophilic asthma

303

317

10.33

262.38

1.2

1.0

2.56

5.76

u/ml

1.83

218

140

Nasal polyp

445

725

6.41

261.57

1.2

1.0

2.80

4.63

u/ml

1.87

294

308

Other pulmonary diagnosis

1507

2758

2.78

237.48

1.1

1.0

5.90

5.17

u/ml

0.71

863

1157

ILD differential diagnosis

1483

2727

2.77

231.65

1.1

1.0

5.94

5.08

u/ml

0.89

851

1141

COPD differential diagnosis

1483

2728

2.77

231.52

1.1

1.0

5.94

5.08

u/ml

0.89

851

1141

Atopic dermatitis, strict definition

1081

3678

3.02

230.53

1.1

7.79

6.53

u/ml

1.38

791

1973

Obesity related asthma

666

1709

4.03

228.37

1.1

4.28

5.09

u/ml

0.67

376

736

Excluding asthma or asthma-COPD overlap

1485

2758

2.74

227.89

1.1

1.0

5.95

5.17

u/ml

0.76

851

1157

Childhood asthma (age<16)

586

1125

4.38

204.55

1.1

1.0

8.18

7.16

u/ml

0.51

410

557

Childhood asthma (age<16), excluding more controls

586

1125

4.38

204.41

1.1

1.0

8.18

7.18

u/ml

0.50

410

556

Cough

849

2650

3.16

199.51

1.1

4.60

5.82

u/ml

1.14

482

1333

Diseases of vocal cords and larynx+other diseases of upper respiratory tract, no elsewhere classified

860

2922

2.94

180.66

1.1

1.0

5.37

4.47

u/ml

0.83

472

1268

Oral corticosteroids

1882

5541

2.08

169.10

1.1

5.17

5.29

u/ml

0.09

1108

2712

ILD medications: prednisolone, methylprednisolone, prednisone

2028

5705

2.04

168.52

1.1

5.52

5.60

u/ml

0.06

1181

2849

Diseases of the respiratory system

1097

2052

2.72

166.36

1.1

1.0

6.24

5.22

u/ml

0.86

607

865

Childhood allergy (age < 16)

735

2069

3.12

156.26

1.2

1.1

8.48

8.33

u/ml

0.06

549

1189

Asthma-related pneumonia

557

1690

3.37

147.90

1.1

5.82

5.88

u/ml

0.02

383

801

Asthma, hospital admissions 3, pneumonia

558

1698

3.36

147.46

1.1

5.81

5.94

u/ml

0.06

384

806

Asthma-related pneumonia or sepsis

558

1698

3.36

147.46

1.1

5.81

5.94

u/ml

0.06

384

806

Undetermined asthma, excluding more controls

272

503

5.61

140.00

1.2

1.0

5.37

5.53

u/ml

0.04

155

212

Undetermined asthma

272

506

5.58

139.10

1.2

1.0

5.37

5.46

u/ml

0.02

155

215

Abnormalities of breathing

1732

5227

2.00

138.23

1.1

5.36

6.11

u/ml

0.97

971

2700

ILD medications

2028

6063

1.86

128.99

1.1

5.58

5.80

u/ml

0.20

1188

3086

Inflammatory bowel disease treatment related agents

1997

6199

1.85

126.77

1.1

5.46

5.71

u/ml

0.24

1153

3144

Symptoms and signs involving the circulatory and respiratory systems

1940

5277

1.87

122.05

1.1

5.87

6.13

u/ml

0.24

1092

2729

Deviated nasal septum

471

1472

3.26

119.35

1.1

1.0

4.29

5.06

u/ml

0.50

255

635

Chronic diseases of tonsils and adenoids

1305

4024

2.08

118.43

1.1

1.0

6.02

5.08

u/ml

0.91

726

1836

First line medication for Crohn's disease

1964

5949

1.82

117.32

1.1

5.59

5.82

u/ml

0.21

1144

3033

Adverse effects, not elsewhere classified

531

1816

3.05

116.81

1.1

4.89

5.92

u/ml

0.86

382

985

Other medical care

593

2099

2.81

115.10

1.1

9.67

5.09

u/ml

6.35

445

1024

Dermatitis due to ingested food

262

580

5.02

107.35

1.3

1.1

7.03

7.93

u/ml

0.29

219

357

FESS (DNB20)

305

796

4.01

103.09

1.2

1.1

2.37

5.31

u/ml

4.49

188

402

Urticaria

687

2881

2.45

100.19

1.1

4.98

5.58

u/ml

0.48

439

1549

Ethmoidectomy

308

830

3.87

99.41

1.2

1.1

2.35

5.28

u/ml

4.65

190

416

Biological medicines for asthma

14.95

97.00

1.2

1.0

3.44

10.27

u/ml

1.46

Personal history of allergy to analgesic agent

31.48

94.34

1.5

1.1

1.73

4.67

u/ml

0.72

Urticaria and erythema

751

3373

2.28

93.16

1.1

4.94

5.61

u/ml

0.59

479

1778

Diseases of the skin and subcutaneous tissue

1666

4784

1.76

88.11

1.1

6.01

5.51

u/ml

0.49

986

2296

Dyspnoea

1260

5232

1.87

87.67

1.1

5.26

4.86

u/ml

0.39

721

2625

Other and unspecified effects of external causes

632

2720

2.39

87.06

1.1

4.92

6.24

u/ml

1.39

431

1482

Non-allergic asthma (mode)

296

853

3.51

84.31

1.1

1.0

2.59

5.38

u/ml

2.43

142

371

Non-allergic asthma (mode), excluding more controls

296

854

3.51

84.14

1.1

1.0

2.59

5.40

u/ml

2.45

142

370

Acute upper respiratory infections

1600

5862

1.73

82.88

1.1

5.53

5.63

u/ml

0.07

873

2990

Personal history of allergy to drugs, medicaments and biological substances

13.15

73.42

1.4

1.1

1.68

6.06

u/ml

1.40

Polypectomy (DHB20)

145

291

5.21

68.62

1.3

1.1

1.83

6.03

u/ml

2.84

100

137

Diseases of the eye and adnexa

1602

4878

1.66

68.61

1.1

6.76

5.63

u/ml

1.41

980

2416

Allergic contact dermatitis

293

973

3.11

67.92

1.1

6.20

4.97

u/ml

0.51

162

468

Acute sinusitis

912

4632

1.86

65.21

1.1

5.45

5.78

u/ml

0.19

507

2386

1646

5456

1.61

62.72

1.1

5.46

5.59

u/ml

0.10

896

2729

Dermatitis

762

4008

1.92

61.30

1.1

4.58

4.94

u/ml

0.27

428

1910

Acute upper respiratory infections of multiple and unspecified sites

1223

5474

1.69

61.06

1.1

5.52

5.85

u/ml

0.30

683

2840

Bronchitis

1569

6600

1.57

57.20

1.1

5.90

5.66

u/ml

0.19

874

3372

Any reimbursement code in KELA

1288

3911

1.67

56.15

1.1

6.39

5.90

u/ml

0.41

764

1969

Medical observation and evaluation for suspected diseases and conditions

1083

3219

1.74

55.34

1.1

5.49

5.78

u/ml

0.22

657

1577

D07AA Corticosteroids, weak (group I)

398

1713

2.40

55.19

1.2

1.1

7.99

6.15

u/ml

1.25

290

980

Other and unspecified dermatitis

634

3323

1.93

51.74

1.1

4.26

4.86

u/ml

0.50

358

1591

Other and unspecified urticaria

405

1811

2.29

51.29

1.1

4.72

5.82

u/ml

0.76

250

973

Sleep apnoea, including avohilmo

1197

4911

1.59

46.45

1.1

3.56

4.97

u/ml

3.11

577

2477

Asthma mixed form (mode), excluding more controls

100

209

4.94

45.09

1.1

1.0

4.95

5.06

u/ml

0.02

Asthma mixed form (mode)

100

211

4.90

44.59

1.1

1.0

4.95

5.01

u/ml

0.01

Other special examinations and investigations of persons without complaint or reported diagnosis

1041

3219

1.65

44.02

1.1

6.34

5.78

u/ml

0.38

572

1577

Examination and observation for other reasons

885

3199

1.70

43.34

1.1

4.81

5.74

u/ml

0.94

509

1564

Early onset COPD, excluding more controls

173

547

3.20

43.29

1.0

5.00

3.42

u/ml

0.47

191

Headache

1056

5630

1.58

41.49

1.1

5.62

5.95

u/ml

0.25

557

2939

Special screening examination for infectious and parasitic diseases

554

2210

1.91

41.06

1.1

5.66

6.47

u/ml

0.55

338

1062

Recurrent or chronic depression

703

2933

1.75

39.80

1.1

6.19

6.07

u/ml

0.05

374

1557

Voice disturbances

345

1601

2.19

39.73

1.1

4.15

4.79

u/ml

0.33

182

788

Pain in joint

890

3609

1.65

39.69

1.1

5.10

6.14

u/ml

1.00

499

1918

Migraine, single triptan purchase ok & required. ICD-code if available is included

1277

5809

1.50

38.22

1.1

5.88

6.05

u/ml

0.12

664

3044

Triptan medication for migraine, single purchase ok

1277

5809

1.50

38.22

1.1

5.88

6.05

u/ml

0.12

664

3044

Idiopathic urticaria

143

5.70

38.20

1.1

4.39

5.42

u/ml

0.25

COPD/asthma/ILD related infections

1499

5198

1.45

36.14

1.1

5.61

5.59

u/ml

0.02

809

2615

COPD/asthma related infections

1499

5198

1.45

36.14

1.1

5.61

5.59

u/ml

0.02

809

2615

Migraine

891

4837

1.59

35.29

1.1

5.18

6.50

u/ml

1.58

488

2543

Other acute lower respiratory infections

727

4229

1.66

35.28

1.2

1.1

6.27

6.05

u/ml

0.12

453

2315

Sleep apnoea

1044

4636

1.54

35.22

1.1

3.87

4.81

u/ml

1.36

504

2306

Chronic laryngitis and laryngotracheitis

154

518

3.02

34.93

1.1

1.0

6.06

4.09

u/ml

0.53

210

Symptoms and signs involving speech and voice

374

1900

1.99

33.77

1.1

4.09

4.79

u/ml

0.40

196

937

Depression or dysthymia

959

3457

1.56

33.56

1.1

5.29

6.07

u/ml

0.70

504

1828

Dermatographic urticaria

154

537

2.98

33.20

1.1

2.67

5.51

u/ml

2.29

279

Neurotic, stress-related and somatoform disorders

1344

6687

1.44

32.91

1.1

5.86

5.88

u/ml

0.01

758

3441

Episodal and paroxysmal disorders

1679

6204

1.40

32.57

1.1

5.22

6.10

u/ml

1.31

902

3325

Anxiety disorders

1348

6703

1.44

32.55

1.1

5.84

5.87

u/ml

0.02

763

3445

Asthma and opportunity respiratory infection

5.99

31.93

1.1

2.12

5.06

u/ml

0.72

Gastro-oesophageal reflux disease

779

4372

1.59

31.87

1.1

4.22

4.78

u/ml

0.49

371

2204

Bronchiectasis

140

4.80

29.23

1.0

1.1

2.09

5.59

u/ml

1.33

Temporomandibular joint disorders, including avohilmo

717

4577

1.58

29.05

1.1

5.62

6.08

u/ml

0.31

399

2362

Anxiety disorders, excluding more controls

1220

5703

1.43

28.44

1.1

5.38

5.82

u/ml

0.41

691

2940

Malignant neoplasm, wide definition for exclusion, excluding all cancers (controls excluding all cancers)

537

5222

0.60

28.25

1.1

5.28

4.54

u/ml

0.41

238

2655

Malignant neoplasm, wide definition for exclusion

537

5221

0.60

28.23

1.1

5.28

4.54

u/ml

0.41

238

2655

Malignant neoplasm, excluding all cancers (controls excluding all cancers)

538

5225

0.60

28.15

1.1

5.28

4.54

u/ml

0.41

238

2658

Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified

681

2114

1.63

27.66

1.1

6.66

6.59

u/ml

0.03

360

1126

Sleep disorders (combined)

1225

5691

1.42

27.61

1.1

4.35

5.20

u/ml

1.16

606

2919

Irritable bowel syndrome

396

2198

1.83

27.42

1.1

4.72

5.41

u/ml

0.43

204

1112

COPD

234

883

2.20

26.87

1.0

4.32

3.65

u/ml

0.20

119

352

Malignant neoplasm

508

4958

0.60

26.77

1.1

5.05

4.36

u/ml

0.40

228

2490

Low back pain

973

5169

1.46

26.21

1.1

4.46

5.67

u/ml

1.50

503

2660

Speech therapy

288

1474

1.98

25.63

1.1

2.44

4.98

u/ml

4.01

134

743

All anxiety disorders

1034

5851

1.43

25.47

1.1

6.12

6.21

u/ml

0.06

603

3075

Provisional assignment of new diseases of uncertain etiology

653

4211

1.57

25.46

1.1

5.23

6.13

u/ml

0.61

335

2279

Codes for special purposes

653

4214

1.57

25.38

1.1

5.23

6.13

u/ml

0.62

335

2281

Other headache syndromes

568

3564

1.61

24.92

1.1

5.05

5.17

u/ml

0.06

313

1775

Other chronic obstructive pulmonary disease

217

829

2.19

24.74

1.0

4.45

3.49

u/ml

0.30

112

327

Pain in throat and chest

1070

4615

1.43

24.50

1.1

4.66

5.74

u/ml

1.37

570

2331

Pain (limb, back, neck, head abdominally)

1087

3834

1.43

24.25

1.1

6.16

5.94

u/ml

0.14

603

2092

Dorsalgia

1399

5585

1.36

24.16

1.1

4.93

6.03

u/ml

1.54

747

2927

Any event in cancer register

619

5635

0.65

23.99

1.1

5.37

4.59

u/ml

0.50

279

2874

Persons encountering health services for examination and investigation

936

3219

1.47

23.97

1.1

6.22

5.78

u/ml

0.29

519

1577

Anxiety (asthma-related co-morbidities)

1005

5603

1.43

23.93

1.1

6.09

6.28

u/ml

0.13

583

2929

Covid-19 suspected case

385

2222

1.76

23.57

1.1

4.81

6.29

u/ml

0.79

186

1206

Other dorsopathies, not elsewhere classified

1449

5684

1.35

23.56

1.1

5.13

6.13

u/ml

1.35

763

2992

Conjunctivitis (acute, non atopic)

398

2318

1.73

23.17

1.1

6.84

5.20

u/ml

1.07

245

1212

Tonsillectomy and adenotomy

1117

5621

1.40

23.13

1.1

6.71

6.11

u/ml

0.50

635

3095

Acetic acid derivatives and related substances

365

1062

1.81

21.76

1.1

8.50

7.10

u/ml

0.51

179

602

Depression

1307

6738

1.34

21.37

1.1

5.40

5.89

u/ml

0.50

714

3463

Triptan medication for migraine, min. 3 purchases

931

5239

1.41

21.25

1.1

4.76

5.83

u/ml

1.24

472

2684

Acute bronchitis

465

2838

1.62

21.04

1.1

5.77

5.68

u/ml

0.04

263

1523

Persons encountering health services for specific procedures and health care

1445

6800

1.32

20.98

1.1

6.37

5.38

u/ml

1.28

905

3466

Atopic conjunctivitis

100

356

2.92

20.96

1.2

1.1

7.22

6.84

u/ml

0.08

196

Coxibs

363

1095

1.78

20.79

1.1

7.47

7.19

u/ml

0.08

184

614

Myalgia

316

1786

1.79

20.77

1.1

3.61

5.30

u/ml

1.87

176

909

Parasetamol

1266

4799

1.35

20.72

1.1

6.34

6.33

u/ml

0.00

675

2536

Other disorders of lacrimal gland

358

2101

1.72

20.53

1.1

3.66

5.20

u/ml

1.40

192

1020

Exposure to unspecified factor

1267

7415

1.33

20.10

1.1

5.29

5.76

u/ml

0.45

746

3857

Mood [affective] disorders

1356

6774

1.32

19.98

1.1

5.44

5.90

u/ml

0.47

733

3486

Abnormalities of heart beat

366

2158

1.69

19.90

1.1

5.45

5.51

u/ml

0.02

180

1069

Soft tissue disorders

1517

6054

1.31

19.71

1.1

5.86

6.08

u/ml

0.17

828

3244

Mood disorders

1355

6777

1.32

19.61

1.1

5.45

5.90

u/ml

0.45

732

3489

Disorders of lacrimal system

425

2651

1.62

19.24

1.1

3.77

5.08

u/ml

1.10

220

1273

Dorsopathies

1488

5845

1.31

19.04

1.1

5.68

6.19

u/ml

0.47

786

3117

Lower back pain or/and sciatica

1255

6609

1.32

18.74

1.1

4.29

5.65

u/ml

2.32

646

3354

Diseases of the musculoskeletal system and connective tissue

1026

3762

1.38

18.66

1.1

7.77

6.30

u/ml

1.17

584

2096

Propionic acid derivatives

453

1412

1.63

18.51

1.1

7.03

8.24

u/ml

0.57

248

853

Dental caries 2, only avohilmo

1129

6696

1.34

18.46

1.1

5.90

5.77

u/ml

0.10

642

3511

Other anxiety disorders

768

4834

1.42

18.41

1.1

5.77

6.52

u/ml

0.56

444

2569

Functional dyspepsia

295

1694

1.76

18.37

1.1

3.88

5.22

u/ml

0.80

145

829

Abnormal findings on diagnostic imaging of lung

306

1732

1.73

18.07

1.1

3.99

3.79

u/ml

0.09

143

816

Eosinophilic disease (BM)

7.22

17.96

1.2

1.0

1.28

2.49

u/ml

0.30

Temporomandibular joint disorders

240

1311

1.86

17.77

1.1

5.42

5.07

u/ml

0.12

121

665

Allergic urticaria

157

744

2.16

17.66

1.1

5.92

6.15

u/ml

0.06

109

412

Selective serotonin reuptake inhibitors

1316

5307

1.31

17.58

1.1

5.42

6.12

u/ml

0.75

709

2771

Other specific joint derangements/joint disorders

1107

5597

1.33

17.35

1.1

5.32

6.13

u/ml

0.83

596

2959

Gastrointestinal diseases

1098

4116

1.34

17.23

1.1

6.39

6.20

u/ml

0.11

607

2253

Soft tissue disorders related to use, overuse and pressure

254

1426

1.80

17.11

1.0

1.1

4.91

4.36

u/ml

0.21

126

669

Allergic contact dermatitis due to drugs in contact with skin

102

4.40

16.87

1.1

1.0

7.64

3.24

u/ml

0.55

Dental caries 2

1127

6751

1.32

16.79

1.1

5.92

5.73

u/ml

0.15

642

3538

Dental caries 2 and operation codes

1109

6713

1.32

16.62

1.1

5.89

5.78

u/ml

0.08

632

3517

Bronchitis, not specified as acute or chronic

360

2.62

16.47

1.1

5.06

5.37

u/ml

0.07

167

Neurological diseases

1382

5426

1.29

16.09

1.1

5.86

6.30

u/ml

0.40

753

2946

Opioids

1370

5610

1.29

16.04

1.1

5.37

5.76

u/ml

0.34

715

2881

Exposure to other specified factors

969

6853

1.33

15.97

1.1

5.89

5.93

u/ml

0.02

595

3579

Lichen simplex chronicus and prurigo

254

2.93

15.90

1.1

5.82

4.55

u/ml

0.19

120

Diabetes, insulin treatment (Kela reimbursement)

664

5681

0.71

15.87

1.0

1.1

4.84

4.91

u/ml

0.04

324

2949

Other soft tissue disorders, not elsewhere classified

1215

5797

1.30

15.82

1.1

5.52

5.87

u/ml

0.27

651

3077

Fenamates

184

633

1.98

15.56

1.1

3.23

5.39

u/ml

1.87

101

345

Diabetes, insuline treatment (Kela reimbursement), excluding more controls

650

5543

0.71

15.40

1.1

4.91

4.93

u/ml

0.01

319

2887

Other diseases of hard tissues of teeth

828

4554

1.36

15.35

1.1

5.12

5.52

u/ml

0.30

471

2372

Codeine

1261

5389

1.29

15.27

1.1

4.82

5.48

u/ml

0.75

646

2748

Early onset COPD

173

903

1.93

14.76

1.0

1.1

5.00

4.45

u/ml

0.13

421

Codeine or tramadol medication

1391

6101

1.27

14.59

1.1

4.63

5.40

u/ml

1.01

699

3082

Chronic conjunctivitis

182

3.25

14.56

1.1

5.00

6.25

u/ml

0.29

Renal tubulo-interstitial diseases

531

5797

0.70

14.48

1.1

3.52

5.39

u/ml

3.04

278

2987

Anti-inflammatory and antirheumatic products, non-steroids

432

1415

1.55

14.46

1.1

7.18

8.23

u/ml

0.46

235

856

Migraine with aura

389

2551

1.54

14.42

1.1

4.77

6.00

u/ml

0.91

222

1331

Other antidepressants

1265

5180

1.28

14.14

1.1

5.55

6.00

u/ml

0.39

654

2671

Depression medications

699

2535

1.40

14.09

1.1

6.60

7.13

u/ml

0.30

379

1431

Mood disorders, excluding more controls

1193

5681

1.28

14.06

1.1

5.18

5.82

u/ml

0.68

649

2904

Follow-up examination after treatment for conditions other than malignant neoplasms

544

2477

1.45

14.03

1.1

5.57

5.31

u/ml

0.12

274

1160

Persons encountering health services for other counselling and medical advice, not elsewhere classified

1425

6492

1.26

13.95

1.1

4.97

5.71

u/ml

0.99

823

3368

General symptoms and signs

1513

6089

1.25

13.85

1.1

5.05

5.84

u/ml

1.08

811

3187

Diseases of middle ear and mastoid

891

5547

1.32

13.80

1.1

6.44

6.31

u/ml

0.07

516

3058

Haemorrhage from respiratory passages

240

1309

1.71

13.68

1.1

4.25

5.49

u/ml

0.70

127

631

Neurological diseases, wide definition

659

2381

1.40

13.38

1.1

6.02

6.78

u/ml

0.49

357

1385

Abnormal findings on diagnostic imaging and in function studies, without diagnosis

486

3125

1.45

13.34

1.1

4.23

4.55

u/ml

0.20

238

1534

Other joint disorders

1361

5791

1.26

13.26

1.1

5.85

6.24

u/ml

0.30

737

3092

Secondary uncertain malignant neoplasm, excluding all cancers (controls excluding all cancers)

1668

0.44

13.18

1.0

1.1

6.18

3.41

u/ml

0.46

788

Oxicams

222

716

1.77

13.10

1.1

4.55

5.55

u/ml

0.36

114

392

Diabetes, varying definitions

807

6357

0.76

13.09

1.1

5.04

5.18

u/ml

0.09

400

3324

COPD (mode)

132

511

2.06

13.08

1.0

4.86

3.15

u/ml

0.38

183

Diabetes mellitus

816

6407

0.76

13.04

1.1

4.97

5.17

u/ml

0.13

408

3349

TMD related operations

232

1382

1.70

12.91

1.1

4.52

5.45

u/ml

0.46

125

701

Somatoform disorder

214

1247

1.74

12.90

1.1

4.65

5.47

u/ml

0.36

109

625

Abdominal and pelvic pain

1346

5409

1.26

12.89

1.1

5.24

5.97

u/ml

0.72

712

2916

Acute bronchiolitis

196

1006

1.81

12.82

1.3

1.1

7.69

7.63

u/ml

0.02

152

680

Pain and other conditions associated with female genital organs and menstrual cycle

354

2240

1.53

12.78

1.1

5.05

5.97

u/ml

0.48

182

1176

Migraine without aura

362

2406

1.52

12.72

1.1

5.84

6.19

u/ml

0.14

205

1285

Diseases of oesophagus, stomach and duodenum

1241

6004

1.26

12.70

1.1

4.13

5.20

u/ml

1.78

627

3107

Schizophrenia or delusion

166

2950

0.56

12.68

1.0

1.1

3.29

6.43

u/ml

3.11

1573

Diabetes medication

794

6344

0.76

12.66

1.1

4.75

5.12

u/ml

0.27

390

3304

Pruritus

123

608

2.05

12.42

1.1

5.60

4.89

u/ml

0.19

287

Schizophrenia, schizotypal and delusional disorders

168

2955

0.56

12.37

1.0

1.1

3.29

6.42

u/ml

3.10

1575

Migraine with aura and triptan purchases

269

1689

1.62

12.24

1.1

5.49

5.79

u/ml

0.11

154

908

Cystitis

1039

4980

1.28

12.17

1.1

5.57

5.29

u/ml

0.17

517

2554

Diseases of the ear and mastoid process

1578

6542

1.22

12.10

1.1

6.09

5.45

u/ml

0.69

836

3422

Dentofacial anomalies [including malocclusion]

420

2882

1.45

11.85

1.1

4.58

6.06

u/ml

1.30

226

1538

Paracetamol of NSAID medication

320

1030

1.58

11.82

1.1

8.46

8.13

u/ml

0.09

181

656

Schizophrenia

1417

0.40

11.57

1.0

1.1

3.37

6.56

u/ml

1.90

760

Other bacterial diseases

603

5610

0.74

11.56

1.0

1.1

5.27

5.00

u/ml

0.15

332

2917

Preparation and fitting of bite rail to mouth

192

1123

1.73

11.51

1.1

3.74

5.47

u/ml

1.11

103

566

Acute pharyngitis

264

1666

1.60

11.42

1.1

7.85

6.78

u/ml

0.40

156

988

Kela-code for severe mental illness

204

3341

0.61

11.40

1.1

2.67

6.05

u/ml

7.15

109

1765

Malignant neoplasm of breast, excluding all cancers (controls excluding all cancers)

205

2207

0.60

11.40

1.1

4.13

3.14

u/ml

0.35

1000

Malignant neoplasm of breast, HER2-negative, excluding all cancers (controls excluding all cancers)

205

2207

0.60

11.40

1.1

4.13

3.14

u/ml

0.35

1000

Symptoms and signs involving the skin and subcutaneous tissue

736

5609

1.31

11.14

1.1

5.87

5.00

u/ml

0.51

400

2854

ILD, hospital admissions 1, main diag only

345

2.28

10.47

1.1

3.98

3.50

u/ml

0.12

162

Intestinal infectious diseases

1155

7302

1.24

10.40

1.1

5.28

5.82

u/ml

0.48

662

3840

ILD, hospital admissions

385

2.20

10.35

1.1

3.90

3.77

u/ml

0.03

185

Other interstitial pulmonary diseases

386

2.19

10.29

1.1

3.89

3.77

u/ml

0.03

185

Interstitial lung disease

387

2.19

10.22

1.1

3.90

3.77

u/ml

0.03

185

Interstitial lung disease endpoints

387

2.19

10.22

1.1

3.90

3.77

u/ml

0.03

185

Symptoms and signs involving the digestive system and abdomen

1318

5411

1.22

10.18

1.1

4.91

5.96

u/ml

1.26

701

2918

Rotator cuff syndrome

507

2754

1.37

10.11

1.1

4.09

3.81

u/ml

0.14

239

1262

Eosinophilia

4.18

10.07

1.2

1.1

1.28

6.36

u/ml

1.36

Cervicocranial syndrome

117

614

1.93

10.05

1.1

7.59

5.21

u/ml

0.49

304

Emphysema

3.68

9.97

1.1

1.78

5.31

u/ml

1.09

Drugs, medicaments and biological substances causing adverse effects in therapeutic use

110

568

1.97

9.95

1.1

2.85

5.39

u/ml

2.16

305

Malignant neoplasm of breast

203

2335

0.62

9.94

1.1

4.02

3.04

u/ml

0.36

1036

Non-allergic asthma

420

2.12

9.85

1.0

1.1

1.11

4.88

u/ml

3.54

184

Other and unspecified nonorganic psychotic disorders

117

2125

0.54

9.84

1.0

1.1

2.86

7.25

u/ml

6.49

1166

Migraine without aura and triptan purchases

275

1829

1.52

9.79

1.1

6.38

5.80

u/ml

0.19

150

987

Allergic colitis

462

2.12

9.72

1.2

1.1

8.95

7.07

u/ml

0.28

317

Sciatica+with lumbago

506

3557

1.36

9.70

1.1

3.44

4.60

u/ml

1.42

263

1757

Other chronic obstructive pulmonary disease, including avohilmo

291

1617

1.50

9.70

1.0

1.1

3.75

3.76

u/ml

0.00

148

739

Schizophrenia or delusion, excluding more controls

166

2718

0.60

9.67

1.0

1.1

3.29

6.12

u/ml

2.63

1429

Inflammatory diseases of female pelvic organs

793

4695

1.28

9.63

1.1

5.28

5.04

u/ml

0.15

409

2316

Disturbances of skin sensation

337

2346

1.45

9.46

1.1

5.21

5.10

u/ml

0.04

188

1191

Other diseases of urinary system

1219

5636

1.22

9.39

1.1

5.15

5.38

u/ml

0.17

635

2931

Trochanteric bursitis

115

614

1.89

9.38

1.1

3.93

4.12

u/ml

0.05

282

Pain in thoracic spine

172

1036

1.68

9.31

1.1

5.56

6.16

u/ml

0.18

512

Disorders of eyelid, lacrimal system and orbit

828

5152

1.26

9.29

1.1

3.96

4.86

u/ml

1.08

428

2586

Mouth breathing

418

3027

1.39

9.29

1.1

4.84

5.17

u/ml

0.17

221

1629

Other and unspecified tonsillitis

571

3675

1.33

9.25

1.1

7.40

6.59

u/ml

0.46

312

2064

Persons encountering health services in other circumstances, wide

1496

6507

1.20

9.23

1.1

5.22

5.72

u/ml

0.56

835

3375

Transport accidents

596

4037

1.32

9.19

1.1

7.89

6.03

u/ml

1.11

332

2045

Benign neoplasm: Colon

286

1896

1.48

9.18

1.0

1.1

2.90

3.54

u/ml

0.48

139

862

Dental caries 2 and operation codes, only avohilmo

942

4699

1.25

9.16

1.1

5.82

5.89

u/ml

0.05

527

2500

Vaginitis/vulvovaginitis/vulvitis/abscess of vulva

254

1686

1.52

9.15

1.1

6.42

5.62

u/ml

0.30

132

882

Type 2 diabetes

703

5335

0.78

9.15

1.1

4.36

4.49

u/ml

0.09

335

2675

Suppurative and unspecified otitis media

629

4302

1.31

9.09

1.1

6.81

6.68

u/ml

0.07

370

2444

Other enthesopathies

294

2010

1.47

9.07

1.2

1.1

4.91

4.35

u/ml

0.24

146

942

Other nutritional deficiencies

772

5977

1.27

9.06

1.1

4.32

5.38

u/ml

1.43

414

3041

Other respiratory diseases principally affecting the interstitium

489

1.98

9.00

1.1

3.53

3.75

u/ml

0.06

239

Mental and behavioural disorders due to alcohol, excluding acute intoxication

208

3200

0.65

8.96

1.1

3.57

5.63

u/ml

1.64

110

1656

Disorders of skin appendages

604

4649

1.31

8.95

1.1

6.06

6.24

u/ml

0.09

327

2483

Respiratory diseases principally affecting the interstitium, IBD co-morbidites

319

2.07

8.93

1.1

3.73

4.98

u/ml

0.33

160

Enthesopathies of lower limb, excluding foot

233

1526

1.54

8.88

1.1

4.45

5.46

u/ml

0.42

123

741

Oter anti-inflammatory and antirheumatic agents, non-steroids

154

490

1.75

8.87

1.1

2.55

4.58

u/ml

1.26

250

Injuries to the wrist and hand

1213

7295

1.21

8.84

1.1

5.71

5.77

u/ml

0.04

657

3833

Vocal cord dysfunction

167

938

1.67

8.83

1.2

1.1

4.91

5.02

u/ml

0.02

477

Oedema, not elsewhere classified

254

1686

1.51

8.83

1.1

2.86

4.77

u/ml

2.54

146

848

Unspecified threat to breathing

3.81

8.74

1.2

1.1

2.93

6.65

u/ml

0.86

Dermatitis due to substances taken internally

328

2.20

8.73

1.1

1.0

12.04

5.24

u/ml

1.51

169

Organic, including symptomatic, mental disorders

1064

0.49

8.67

1.0

1.1

5.13

3.62

u/ml

0.26

500

Accidents

1137

4680

1.22

8.64

1.1

5.86

5.54

u/ml

0.24

643

2358

Disorders of the thyroid gland

1082

5811

1.22

8.60

1.1

4.51

5.42

u/ml

1.13

533

2976

Chronic gastritis

158

951

1.67

8.55

1.1

1.0

1.97

3.79

u/ml

1.68

436

Injury, poisoning and certain other consequences of external causes

825

3286

1.26

8.54

1.1

6.93

5.29

u/ml

1.54

463

1684

Alcohol use disorder, Swedish definition

288

3828

0.70

8.50

1.1

3.96

5.42

u/ml

1.03

147

1971

Other intervertebral disc disorders

871

4286

1.25

8.45

1.1

3.50

4.87

u/ml

2.62

422

2154

Nummular dermatitis

319

2.19

8.44

1.1

3.21

4.88

u/ml

0.51

150

COPD, hospital admissions

216

1184

1.55

8.41

1.0

1.1

4.45

3.80

u/ml

0.19

112

530

Injuries to the ankle and foot

947

7047

1.23

8.40

1.1

6.37

5.95

u/ml

0.30

554

3742

Simple and mucopurulent chronic bronchitis

106

3.15

8.39

1.0

1.1

6.37

7.21

u/ml

0.05

COPD, early/later onset

217

1190

1.54

8.34

1.0

1.1

4.45

3.79

u/ml

0.19

112

531

Prurigo nodularis

3.69

8.33

1.0

1.08

4.20

u/ml

1.30

Alcohol dependence

1641

0.53

8.33

1.1

2.55

5.41

u/ml

1.75

833

Cervicobrachial syndrome

222

1461

1.53

8.31

1.1

3.60

4.77

u/ml

0.73

110

680

Lumbar disc prolapse

632

3917

1.29

8.25

1.1

3.63

4.67

u/ml

1.32

313

1940

Malignant neoplasm of breast, HER2-negative

198

2232

0.65

8.24

1.1

4.23

2.98

u/ml

0.46

985

Alcohol use disorder, ICD-based

194

2971

0.65

8.19

1.1

3.20

5.68

u/ml

2.16

100

1533

Other menopausal disorders

272

1060

1.49

8.17

1.1

1.93

3.73

u/ml

2.32

133

473

Secondary malignant neoplasm of other and unspecified sites, excluding all cancers (controls excluding all cancers)

785

0.33

8.16

1.0

1.1

0.50

3.11

u/ml

6.77

360

Arthropathies

1372

5878

1.19

8.14

1.1

6.23

6.20

u/ml

0.02

753

3164

External causes of morbidity and mortality

975

3979

1.23

8.12

1.1

6.07

5.51

u/ml

0.41

542

2031

Pain in limb

907

5343

1.23

8.03

1.1

5.85

5.60

u/ml

0.14

481

2795

Unspecified mental disorder

272

3884

0.70

8.02

1.1

3.03

5.93

u/ml

4.61

145

2060

Other (not insulin) diabetes medications

637

4881

0.78

8.00

1.0

1.1

3.59

4.43

u/ml

0.83

292

2422

Benign neoplasm: Colon, unspecified

126

730

1.74

7.90

1.0

1.1

2.69

3.33

u/ml

0.32

334

Postviral fatigue syndrome

3.57

7.87

1.1

2.82

8.38

u/ml

1.23

Malignant neoplasm of digestive organs, excluding all cancers (controls excluding all cancers)

1383

0.56

7.84

1.0

1.1

6.96

3.28

u/ml

0.82

640

Other and unspecified rosacea

480

1.92

7.83

1.1

1.0

4.02

4.79

u/ml

0.21

225

Polyarthropathies

481

4200

0.76

7.81

1.1

4.63

5.28

u/ml

0.40

241

2135

Occupational exposure to risk-factors

150

2.72

7.80

1.1

7.63

6.25

u/ml

0.16

Dislocation, sprain and strain of joints and ligaments of knee

762

5700

1.25

7.79

1.1

5.48

5.64

u/ml

0.10

409

2921

361

4394

0.73

7.78

1.1

3.94

5.60

u/ml

1.46

185

2288

Shoulder lesions

714

3472

1.26

7.74

1.1

3.84

4.40

u/ml

0.41

331

1657

Other noninfective gastroenteritis and colitis

285

2005

1.43

7.63

1.2

1.1

6.75

6.21

u/ml

0.16

171

1128

Lichen simplex chronicus

146

2.72

7.62

1.1

7.27

4.66

u/ml

0.19

Female infertility, cervigal, vaginal, other or unspecified origin

411

2043

1.36

7.55

1.1

4.78

5.56

u/ml

0.47

191

1036

ILD, hospital admission 2, with pulmonary infections

212

2.38

7.51

1.1

1.0

5.36

3.75

u/ml

0.28

Substance abuse

359

4634

0.74

7.49

1.1

4.67

5.73

u/ml

0.64

194

2413

Type 2 diabetes, strict (exclude DM1)

639

4807

0.79

7.49

1.1

3.90

4.45

u/ml

0.45

293

2381

Hyperkinetic disorders, excluding more controls

242

1619

1.48

7.48

1.1

5.52

8.25

u/ml

1.61

152

1006

Generalized anxiety disorder

250

1729

1.46

7.44

1.1

5.86

6.59

u/ml

0.29

148

942

Mental and behavioural disorders due to psychoactive substance use

376

4755

0.74

7.44

1.1

4.65

5.83

u/ml

0.76

200

2470

Type 2 diabetes, definitions combined

640

4797

0.79

7.30

1.1

3.89

4.43

u/ml

0.45

294

2377

Benign neoplasm of other and ill-defined parts of digestive system

122

718

1.71

7.29

1.1

3.07

4.02

u/ml

0.42

336

335

4180

0.73

7.27

1.1

4.18

5.59

u/ml

1.05

174

2169

Factors influencing health status and contact with health services

388

1428

1.37

7.26

1.1

6.71

6.08

u/ml

0.24

217

666

Heartburn

111

639

1.76

7.22

1.1

4.92

5.31

u/ml

0.06

328

Disorders of synovium and tendon

559

3948

1.28

7.19

1.1

4.21

4.85

u/ml

0.50

283

1965

Other diseases of oesophagus

327

2.07

7.17

1.1

6.20

5.28

u/ml

0.12

164

Other and unspecified drugs and medicaments

495

1.86

7.16

1.1

2.86

5.79

u/ml

2.05

256

Other disorders of patella

221

1503

1.48

7.16

1.1

3.78

5.26

u/ml

1.07

116

733

Acute suppurative otitis media

502

3637

1.30

7.15

1.1

7.63

7.06

u/ml

0.28

309

2118

Biguanides

609

4725

0.79

7.13

1.0

1.1

3.61

4.46

u/ml

0.79

274

2338

Later onset COPD, excluding more controls

137

2.51

7.11

1.0

0.58

1.04

u/ml

0.36

General examination and investigation of persons without complaint and reported diagnosis

751

3219

1.25

7.10

1.1

4.99

5.78

u/ml

0.67

398

1577

Other inflammation of eyelid

128

770

1.68

7.09

1.1

3.88

5.08

u/ml

0.51

403

Benign neoplasm: Colon, unspecified

126

750

1.68

7.07

1.0

1.1

2.69

2.89

u/ml

0.09

335

Hypertrophy of breast in women and men

222

1519

1.47

6.98

1.1

4.62

4.94

u/ml

0.10

104

735

Obesity and other hyperalimentation

716

5752

1.24

6.93

1.1

3.87

5.34

u/ml

2.53

388

2903

Female infertility

457

2155

1.32

6.89

1.0

1.1

5.18

5.60

u/ml

0.23

216

1102

Other/unspecified dorsalgia

363

2693

1.35

6.87

1.1

4.54

5.21

u/ml

0.37

211

1371

Type 2 diabetes, definitions combined, including avohilmo

662

4868

0.80

6.86

1.1

4.00

4.46

u/ml

0.37

313

2415

Obesity

713

5736

1.24

6.86

1.1

3.87

5.34

u/ml

2.50

385

2900

Internal derangement of knee

393

2960

1.33

6.83

1.1

5.69

5.26

u/ml

0.12

197

1464

Diarrhoea and gastroenteritis of presumed infectious origin

855

6423

1.21

6.82

1.1

4.87

5.92

u/ml

1.36

501

3421

Olecranon bursitis

222

2.28

6.82

1.0

1.1

5.91

5.37

u/ml

0.06

105

Hypothyroidism, other/unspecified

999

5510

1.20

6.81

1.1

4.26

5.33

u/ml

1.50

495

2809

Seborrhoeic dermatitis

453

1.87

6.79

1.1

4.91

4.57

u/ml

0.09

224

Mental and behavioural disorders due to alcohol

293

3906

0.73

6.77

1.1

3.61

5.66

u/ml

2.03

154

2035

Other external causes of accidental injury

1111

4680

1.19

6.74

1.1

5.89

5.54

u/ml

0.26

637

2358

Parodontitis or/and operation codes

482

3680

0.78

6.71

1.1

3.80

5.29

u/ml

1.64

254

1893

Other and unspecified vaccines and biological substances

4.05

6.68

1.2

1.1

2.60

5.46

u/ml

0.46

Insulin medication

340

3890

0.74

6.66

1.0

1.1

6.34

5.38

u/ml

0.41

173

2121

Hard cardiovascular diseases

344

2951

0.75

6.51

1.0

1.1

2.88

3.90

u/ml

0.90

152

1411

Diaphragmatic hernia

224

1556

1.45

6.49

1.1

2.89

4.12

u/ml

0.94

119

712

Benign neoplasm of other and ill-defined parts of digestive system

122

743

1.65

6.46

1.1

3.07

3.86

u/ml

0.34

350

Heart failure, not strict

323

2991

0.74

6.38

1.0

1.1

4.60

4.10

u/ml

0.19

148

1467

Benign neoplasm: Liver/bile ducts

137

2.62

6.35

1.0

1.1

1.51

5.20

u/ml

1.57

Care involving use of rehabilitation procedures

622

4766

1.24

6.35

1.1

3.20

4.72

u/ml

2.62

351

2401

Peritonsillar abscess

213

1474

1.45

6.34

1.1

1.0

4.76

5.06

u/ml

0.14

117

692

Cerebrovascular diseases

271

2669

0.73

6.27

1.1

3.71

3.95

u/ml

0.10

122

1278

Other specified disorders of external ear

109

2.79

6.24

1.0

4.66

7.88

u/ml

0.46

Dislocation, sprain and strain of joints and ligaments at neck level

219

1534

1.44

6.18

1.1

6.81

6.50

u/ml

0.09

126

829

Acute and transient psychotic disorders

958

0.48

6.15

1.0

1.1

8.00

5.91

u/ml

0.26

484

Hypertrophy of breast

201

1386

1.46

6.15

1.1

4.39

4.51

u/ml

0.03

659

Cervicalgia

179

1206

1.49

6.12

1.1

5.17

5.26

u/ml

0.03

581

COPD, hospital admissions 1, only main diagnosis

146

797

1.56

6.11

1.0

1.1

3.34

3.98

u/ml

0.17

370

Benign neoplasm: Liver/bile ducts

140

2.56

6.09

1.0

1.1

1.51

5.36

u/ml

1.50

Unspecified privation

113

687

1.66

6.09

1.1

5.87

5.39

u/ml

0.12

352

Cervical disc disorders

271

1971

1.38

6.08

1.1

1.66

3.99

u/ml

7.00

125

901

Infective dermatitis

552

1.74

6.04

1.1

5.49

4.18

u/ml

0.30

251

Acute laryngitis and tracheitis

228

1591

1.43

6.03

1.2

1.1

5.25

7.65

u/ml

1.51

139

969

Restless leg syndrome

104

620

1.69

6.03

1.1

7.23

4.65

u/ml

0.56

311

Behavioural and emotional disorders with onset usually occurring in childhood and adolescence

433

3075

1.29

6.02

1.1

5.84

7.94

u/ml

1.71

258

1871

Obesity, other/unspecified

385

2957

1.31

6.02

1.1

3.28

5.42

u/ml

3.53

219

1508

Stroke, including SAH

188

2016

0.69

5.98

1.0

1.1

3.11

3.57

u/ml

0.18

963

Diseases of external ear

317

2373

1.34

5.94

1.1

6.64

5.78

u/ml

0.35

191

1281

Herpesviral [herpes simplex] infections

129

816

1.60

5.94

1.1

8.06

5.22

u/ml

0.88

422

Otalgia

107

647

1.68

5.93

1.1

4.21

5.57

u/ml

0.48

379

Rosacea

116

717

1.63

5.87

1.1

4.69

5.31

u/ml

0.15

352

Hypothyreosis and Thyroxine purchase for inclusion criteria

1014

5680

1.18

5.86

1.1

4.23

5.25

u/ml

1.42

500

2890

Benign neoplasm: Liver

125

2.63

5.86

1.0

1.1

1.67

6.03

u/ml

1.44

Genitourinary diseases

894

3752

1.20

5.81

1.1

5.94

6.48

u/ml

0.38

492

2152

Dysphagia

166

1114

1.50

5.80

1.1

3.99

4.88

u/ml

0.30

545

STROKE

289

2695

0.74

5.80

1.0

1.1

3.16

4.19

u/ml

0.75

137

1289

Ganglion

233

1669

1.41

5.78

1.1

4.33

5.45

u/ml

0.56

125

820

Benign neoplasm: Liver

126

2.61

5.77

1.0

1.1

1.67

5.38

u/ml

1.34

Disorders of thyroid, IBD co-morbidities

236

1226

1.41

5.77

1.0

1.1

3.78

5.57

u/ml

1.45

122

640

GASTRO-related operations

1256

5432

1.16

5.75

1.1

6.31

6.10

u/ml

0.13

683

2904

Any gastric operation

1256

5432

1.16

5.75

1.1

6.31

6.10

u/ml

0.13

683

2904

Irregular menses

674

4496

1.22

5.74

1.1

4.99

5.28

u/ml

0.20

352

2246

Hypothyroidism, strict autoimmune

854

4739

1.20

5.73

1.1

4.43

5.13

u/ml

0.69

413

2418

Emergency coronary revascularization (for ACS)

1168

0.61

5.71

1.1

1.0

2.56

3.13

u/ml

0.20

528

Substance abuse, excluding more controls

359

4076

0.77

5.71

1.1

4.67

5.89

u/ml

0.75

194

2087

Continuous positive airway pressure

183

1082

1.47

5.67

1.1

3.26

3.86

u/ml

0.30

610

Disorders of breast

529

3942

1.25

5.66

1.1

4.63

4.30

u/ml

0.19

269

1904

Striking against or struck by other objects

410

3204

1.29

5.63

1.1

6.33

6.97

u/ml

0.31

233

1829

Other disorders of eye and adnexa

163

1100

1.50

5.61

1.1

3.33

5.85

u/ml

2.15

593

Correction of physiology of bite - demanding therapy visit

582

1.69

5.57

1.1

7.69

5.68

u/ml

0.46

308

Bruxism

141

2.48

5.54

1.1

4.19

3.73

u/ml

0.07

Other and unspecified polyneuropathies, also in other diseases

101

614

1.65

5.45

1.1

5.76

4.16

u/ml

0.45

282

Ocular pain

102

624

1.66

5.44

1.0

1.1

3.28

5.72

u/ml

1.39

331

Persons with potential health hazards related to family and personal history and certain conditions influencing health status

811

6530

0.84

5.35

1.1

4.86

5.11

u/ml

0.16

422

3427

Malignant neoplasm of breast, ER-positive, excluding all cancers (controls excluding all cancers)

130

1595

0.66

5.29

1.1

2.83

2.59

u/ml

0.10

684

COPD related to multimorbidity

151

850

1.50

5.27

1.0

1.1

3.47

3.76

u/ml

0.09

377

Coronary revascularization (ANGIO or CABG)

1076

0.61

5.26

1.1

1.0

2.63

2.95

u/ml

0.10

498

Malaise and fatigue

425

2799

1.27

5.23

1.1

3.96

5.45

u/ml

1.99

238

1469

Fibromyalgia

104

646

1.63

5.22

1.1

5.02

5.47

u/ml

0.12

310

Diseases of oral cavity, salivary glands and jaws

1059

4660

1.17

5.21

1.1

5.67

5.46

u/ml

0.14

572

2429

Dislocation, sprain and strain of joints and ligaments at wrist and hand level

352

2730

1.30

5.20

1.1

5.49

6.17

u/ml

0.31

205

1464

Other contact dermatitis

487

1.72

5.17

1.1

6.35

4.33

u/ml

0.43

229

Sequelae of other external causes

257

2.01

5.15

1.1

5.42

5.28

u/ml

0.02

131

Other disorders of urethra and urinary system

706

4413

1.20

5.14

1.1

5.07

4.97

u/ml

0.05

354

2199

Tinnitus

183

1289

1.43

5.05

1.1

6.33

4.85

u/ml

0.41

628

Hypermobility syndrome

576

1.66

5.05

1.1

6.64

5.72

u/ml

0.14

309

ILD-related respiratory insufficiency

3.31

5.04

1.1

1.68

4.15

u/ml

—

Subjective visual disturbances

227

1660

1.38

5.04

1.1

4.17

5.74

u/ml

1.23

135

859

Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis

659

4474

1.21

5.02

1.1

4.67

u/ml

0.00

305

2212

Inflammatory diseases of prostate (prostatitis)

469

1.72

4.99

1.1

4.27

6.01

u/ml

0.70

237

Embedded and impacted teeth

494

3403

1.24

4.99

1.1

7.39

7.85

u/ml

0.20

282

1957

TMD related pain

282

1.95

4.98

1.1

5.83

4.87

u/ml

0.19

148

Disturbance of activity and attention

237

1732

1.37

4.97

1.1

4.83

8.09

u/ml

2.62

149

1090

Benign neoplasm of colon, rectum, anus and anal canal

331

2307

1.30

4.95

1.1

2.92

3.64

u/ml

0.61

157

1057

Injuries to the knee and lower leg

1405

7078

1.14

4.94

1.1

5.67

5.79

u/ml

0.09

755

3694

Accidental poisoning by and exposure to other and unspecified chemicals and noxious substances

297

1.92

4.93

1.1

6.03

6.52

u/ml

0.06

174

Other degenerative diseases of the nervous system

997

0.60

4.92

1.0

3.91

5.03

u/ml

0.29

490

Immunodeficiencies

347

1.84

4.92

1.1

6.13

6.54

u/ml

0.07

199

Excessive, frequent and irregular menstruation

555

2518

1.23

4.91

1.1

5.59

5.94

u/ml

0.18

279

1324

Type 2 diabetes, wide definition

414

3383

0.80

4.88

1.0

1.1

4.97

4.14

u/ml

0.43

187

1629

Mental retardation, wide definition

600

0.42

4.78

1.2

0.52

5.62

u/ml

12.41

413

Other and unspecified disorders of vitreous body

213

1547

1.37

4.76

1.0

1.1

2.14

3.23

u/ml

1.12

100

662

Any operation in hilmo

257

1.72

4.76

1.1

11.29

9.68

u/ml

0.21

144

COPD, hospital admission 2, with asthma infections

132

751

1.50

4.72

1.1

4.27

4.48

u/ml

0.04

353

Mental and behavioural disorders due to multiple drug use and use of multiple drugs and use of other psychoactive substances

763

0.49

4.71

1.1

6.34

7.22

u/ml

0.11

415

Subacute thyroiditis

191

2.13

4.70

1.0

1.1

3.28

4.50

u/ml

0.33

Impacted teeth

370

2726

1.27

4.69

1.1

6.82

8.37

u/ml

0.84

210

1584

All influenza

244

1830

1.34

4.63

1.1

6.43

5.94

u/ml

0.11

141

1000

Other enthesopathy of foot (+metatarsalgia)

627

1.59

4.63

1.1

2.36

5.55

u/ml

2.54

304

Hypothyroidism and >3 levothyroxin purchases

492

2298

1.24

4.61

1.1

5.60

6.31

u/ml

0.39

262

1284

Hypothyroidism, levothyroxine purchases

492

2298

1.24

4.61

1.1

5.60

6.31

u/ml

0.39

262

1284

Other systemic involvement of connective tissue (FG)

211

1538

1.37

4.61

1.1

5.90

4.84

u/ml

0.33

105

739

Insulin, combination of fast acting with intermediate-acting or long-acting

340

3973

0.79

4.60

1.0

1.1

6.34

5.33

u/ml

0.43

173

2145

COPD-related respiratory insufficiency

226

2.00

4.59

1.0

1.1

0.82

4.95

u/ml

3.35

Renal failure

112

1544

0.66

4.59

1.0

1.1

6.11

4.68

u/ml

0.30

792

Correction of physiology of bite - very demanding therapy visit

214

2.05

4.57

1.1

4.58

5.25

u/ml

0.10

104

Other systemic involvement of connective tissue

213

1568

1.36

4.57

1.1

6.03

4.85

u/ml

0.39

107

776

Spondylolisthesis/Spondylolysis

141

966

1.47

4.56

1.1

5.78

4.80

u/ml

0.24

457

Hyperkinetic disorders

250

1868

1.34

4.56

1.1

5.34

8.12

u/ml

1.82

160

1174

Stroke, excluding SAH

173

1793

0.72

4.54

1.0

1.1

2.99

3.53

u/ml

0.21

850

Thyroiditis

484

1.67

4.52

1.0

1.1

3.02

5.09

u/ml

1.05

254

Vasomotor rhinitis (mode)

371

1.77

4.52

1.1

3.29

5.05

u/ml

0.52

188

Mental retardation

585

0.43

4.51

1.2

0.52

5.69

u/ml

12.45

407

Schizoaffective disorder

671

0.47

4.50

1.0

1.1

1.23

6.51

u/ml

8.14

353

Otitis externa

230

1719

1.35

4.50

1.1

7.37

6.06

u/ml

0.46

140

924

Oesophagitis

215

2.02

4.47

1.2

1.1

3.67

5.29

u/ml

0.47

110

Infections of the skin and subcutaneous tissue

642

5380

1.19

4.47

1.1

5.77

5.81

u/ml

0.02

365

2914

malignant neoplasm of male genital organs, excluding all cancers (controls excluding all cancers)

677

0.58

4.43

1.0

1.1

6.40

3.86

u/ml

0.29

319

TMD muscular pain linked with fibromyalgia

3.21

4.43

1.2

1.0

6.80

2.13

u/ml

—

Hypothyroidism (congenital or acquired)

495

2324

1.23

4.39

1.1

5.62

6.29

u/ml

0.37

267

1304

Inflammatory disease of uterus

188

1369

1.38

4.38

1.1

3.87

5.27

u/ml

0.98

105

688

Acute tubulo-interstitial nephritis

391

4301

0.80

4.37

1.1

3.34

5.52

u/ml

3.53

214

2215

Other diseases of the respiratory system

103

667

1.55

4.36

1.1

6.37

4.45

u/ml

0.35

350

Other respiratory disorders and diseases

103

667

1.55

4.36

1.1

6.37

4.45

u/ml

0.35

350

Visual disturbances

432

3511

1.23

4.34

1.1

3.89

5.58

u/ml

2.29

248

1851

Panic disorder

225

1688

1.34

4.33

1.1

5.80

6.31

u/ml

0.21

134

894

Condition for Implicit Sepsis (Organ dysfunction codes)

586

5080

0.84

4.33

1.1

4.93

5.12

u/ml

0.11

318

2614

Septicaemia

161

2157

0.72

4.32

1.0

1.1

7.77

5.33

u/ml

0.74

1155

Transplanted organ and tissue status

688

0.49

4.32

1.1

4.14

5.84

u/ml

0.27

393

Other and unspecified nerve root and plexus disorders, also in other diseases

171

1229

1.40

4.29

1.1

4.00

5.30

u/ml

0.54

610

Other disorders of eyelid

226

1637

1.34

4.29

1.1

4.19

3.93

u/ml

0.09

107

736

Epiphora

2.74

4.28

1.0

1.81

4.38

u/ml

—

Dementia, including avohilmo

596

0.54

4.26

1.0

0.32

2.69

u/ml

5.17

267

Other and unspecified noninflammatory disorders of ovary, fallopian tube and broad ligament

220

1.99

4.26

1.0

1.1

5.34

4.07

u/ml

0.22

112

Pulmonary eosinophilia, not elsewhere classified

3.69

4.23

1.2

1.0

0.56

3.03

u/ml

—

Other disorders of breast

134

925

1.46

4.23

1.1

5.13

4.78

u/ml

0.09

461

Disorders of ocular muscles, binocular movement, accommodation and refraction

584

4862

1.20

4.22

1.1

4.00

6.43

u/ml

4.49

320

2662

Metatarsalgia

571

1.59

4.21

1.1

2.12

4.92

u/ml

2.00

274

Recurring oral aphthae, including avohilmo

140

975

1.45

4.21

1.1

4.89

5.96

u/ml

0.38

539

Ischaemic Stroke, excluding all haemorrhages

153

1621

0.71

4.18

1.0

1.1

2.53

3.44

u/ml

0.41

752

Dementia

556

0.53

4.16

1.0

0.32

2.82

u/ml

5.02

245

Unspecified acute lower respiratory infection

150

1061

1.42

4.15

1.1

5.04

6.45

u/ml

0.60

566

Other septicaemia

134

1874

0.70

4.14

1.1

8.42

5.46

u/ml

0.77

1014

951

5183

1.15

4.13

1.1

5.92

5.60

u/ml

0.23

562

2605

COPD/asthma/ILD related pneumonia or pneumonia derived septicaemia

951

5183

1.15

4.13

1.1

5.92

5.60

u/ml

0.23

562

2605

Noninflammatory disorders of female genital tract

637

2694

1.19

4.13

1.1

6.51

6.42

u/ml

0.04

326

1441

Other immunodeficiencies

2.65

4.12

1.1

4.24

4.98

u/ml

0.09

Benign neoplasm: Sigmoid colon

551

1.59

4.09

1.0

1.1

2.41

3.36

u/ml

0.40

247

Mental retardation, excluding more controls

552

0.45

4.07

1.2

0.52

6.88

u/ml

14.53

380

Noninfective enteritis and colitis

501

4158

1.21

4.07

1.1

6.58

5.84

u/ml

0.33

263

2286

Single spontaneous delivery

328

2200

0.79

4.07

1.1

5.55

6.01

u/ml

0.20

184

1161

Other diseases of lip and oral mucosa

123

842

1.47

4.05

1.1

5.65

5.04

u/ml

0.14

396

Mental and behavioural disorders due to opioids

391

0.35

4.03

1.1

4.20

7.08

u/ml

—

214

Other gastritis (incl. Duodenitis)

138

968

1.43

3.99

1.2

1.1

3.25

4.66

u/ml

0.75

467

Autoimmune diseases excluding thyroid diseases

1033

6524

0.88

3.99

1.1

6.76

5.74

u/ml

0.79

540

3508

Other general symptoms and signs

559

1.58

3.98

1.1

2.12

6.69

u/ml

5.10

364

Pain, not elsewhere classified

278

2174

1.28

3.96

1.1

4.93

5.64

u/ml

0.27

146

1146

Benign neoplasm: Transverse colon

275

1.83

3.96

1.0

2.62

3.39

u/ml

0.25

124

Anomalies of dental arch relationship, including avohilmo

312

2222

1.27

3.95

1.1

7.21

6.66

u/ml

0.21

187

1294

Certain disorders involving the immune mechanism

175

1283

1.37

3.93

1.1

5.14

5.30

u/ml

0.05

102

662

Acute appendicitis, no complications

648

5511

1.18

3.93

1.1

4.76

5.39

u/ml

0.49

329

2834

Dialysis, with operation codes

678

0.51

3.92

1.1

5.50

5.23

u/ml

0.03

371

Chondrocostal junction syndrome [Tietze]

185

2.03

3.91

1.2

1.1

2.52

5.46

u/ml

0.85

Other extrapyramidal and movement disorders in other diseases

154

1107

1.40

3.89

1.1

6.61

5.02

u/ml

0.43

551

Autoimmune diseases excluding thyroid diseases, strict definition

1014

6421

0.88

3.86

1.1

6.87

5.75

u/ml

0.86

524

3454

Unspecified chronic bronchitis

2.79

3.86

1.1

8.30

4.93

u/ml

—

Crossbite

157

1056

1.40

3.83

1.2

1.1

7.60

7.17

u/ml

0.11

111

695

Visual disturbances and blindness

449

3717

1.21

3.82

1.1

3.90

5.55

u/ml

2.36

262

1968

Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium

599

3292

1.19

3.81

1.1

5.34

5.76

u/ml

0.29

323

1725

Gingivitis and periodontal diseases

1003

4541

1.14

3.79

1.1

5.64

u/ml

0.00

540

2329

Postpartum care and examination

180

1540

0.74

3.78

1.1

4.62

5.74

u/ml

0.59

815

Erosion of teeth, including avohilmo

255

1918

1.29

3.78

1.1

5.53

6.58

u/ml

0.46

152

1008

Other reaction to severe stress, and adjustment disorders

481

4015

1.20

3.77

1.1

5.42

5.93

u/ml

0.30

270

2073

Menorrhagia

394

1768

1.24

3.77

1.1

3.63

4.97

u/ml

1.06

182

884

Immunodeficiency with predominantly antibody defects

195

1.99

3.77

1.1

6.88

7.08

u/ml

0.02

116

Disorders of other endocrine glands

467

3824

1.21

3.76

1.1

3.76

5.84

u/ml

2.75

239

2137

Benign neoplasm: Transverse colon

281

1.79

3.71

1.0

2.62

3.43

u/ml

0.26

130

Infections with a predominantly sexual mode of transmission

435

3602

1.21

3.70

1.1

5.11

5.96

u/ml

0.57

228

1901

Peripheral artery disease

983

0.65

3.70

1.1

1.0

4.30

3.36

u/ml

0.15

447

Any dementia, excluding more controls

456

0.52

3.69

1.0

1.23

3.98

u/ml

1.54

202

Other disorders of white blood cells

253

1.84

3.68

1.1

1.64

5.60

u/ml

2.64

132

Malignant neoplasm of skin, excluding all cancers (controls excluding all cancers)

201

1809

0.76

3.68

1.1

3.69

3.16

u/ml

0.22

829

Benign neoplasm: Small intestine

103

2.35

3.68

1.2

1.0

0.99

3.56

u/ml

1.50

Radiculopathy

102

687

1.49

3.67

1.1

3.12

4.44

u/ml

0.42

309

Ovarian cyst

468

2245

1.21

3.66

1.1

4.88

5.47

u/ml

0.36

232

1141

Nonsuppurative otitis media

394

2795

1.23

3.65

1.1

8.05

7.77

u/ml

0.09

247

1648

Urticaria due to cold and heat

2.84

3.65

1.1

11.51

6.14

u/ml

—

Other and unspecified acute skin changes due to ultraviolet radiation

2.89

3.64

1.0

4.67

4.06

u/ml

—

Injury of muscle and tendon at shoulder and upper arm level

215

1645

1.31

3.64

1.1

2.34

4.13

u/ml

2.76

785

Coronary artery bypass grafting

476

0.51

3.63

1.0

4.87

3.86

u/ml

0.12

207

Congenital malformations, deformations and chromosomal abnormalities

792

6612

1.15

3.62

1.1

5.83

6.13

u/ml

0.20

430

3591

Fissure and fistula of anal and rectal regions

208

1586

1.32

3.62

1.1

5.21

5.35

u/ml

0.03

820

Dyshidrosis [pompholyx]

2.40

3.62

1.1

6.52

6.05

u/ml

0.06

Fall on same level involving ice and snow

516

4352

1.19

3.61

1.1

5.20

5.58

u/ml

0.19

282

2229

Metabolic disorders

705

5071

0.86

3.60

1.1

4.26

4.88

u/ml

0.48

347

2597

Polyneuropathies and other disorders of the peripheral nervous system

119

830

1.44

3.59

1.1

5.32

4.45

u/ml

0.25

406

All influenza (not pneumonia)

168

1244

1.36

3.59

1.1

7.32

6.24

u/ml

0.17

696

Cerebrovascular diseases (FINNGEN)

192

1812

0.76

3.59

1.1

3.99

4.16

u/ml

0.05

887

Atypical facial pain

270

1.80

3.59

1.0

1.1

5.18

4.93

u/ml

0.02

135

Abnormal findings in secretions and smears from cervix uteri vagina vulva

617

4144

1.17

3.59

1.1

4.64

4.62

u/ml

0.01

293

2044

Viral pneumonia

118

823

1.44

3.59

1.1

6.46

5.95

u/ml

0.12

435

Thyroiditis, ILD-related definition

134

957

1.41

3.58

1.1

2.17

5.75

u/ml

4.70

494

Other obstetric conditions, not elsewhere classified

604

3344

1.18

3.58

1.1

5.26

5.74

u/ml

0.34

326

1743

Nonalcoholic fatty liver disease

571

1.54

3.58

1.1

3.85

4.68

u/ml

0.24

282

Complications predominantly related to the puerperium

328

2652

1.24

3.58

1.1

4.60

4.85

u/ml

0.12

161

1336

Dental operations, only avohilmo

653

2856

1.17

3.57

1.1

5.16

4.73

u/ml

0.24

337

1423

Keratitis

330

2669

1.24

3.57

1.1

6.78

5.72

u/ml

0.46

186

1383

Ehlers-Danlos syndrome

2.45

3.56

1.1

1.0

10.72

6.39

u/ml

0.35

Impingement syndrome of shoulder

166

1228

1.36

3.55

1.0

1.1

1.73

3.76

u/ml

1.99

557

Any dementia

466

0.53

3.55

1.0

1.13

3.14

u/ml

1.21

202

Disorders of muscles

612

1.51

3.55

1.1

3.37

5.94

u/ml

1.49

301

Sicca syndrome [Sjögren]

430

1.62

3.54

1.1

4.65

4.09

u/ml

0.12

198

195

0.26

3.53

1.0

—

5.07

—

Appendicitis, broad definition

806

6440

1.15

3.52

1.1

4.53

5.26

u/ml

0.71

405

3267

Concussion

606

4489

1.17

3.50

1.1

5.62

6.27

u/ml

0.32

343

2452

Separation of retinal layers (serosa)

179

1.98

3.50

1.1

4.01

4.40

u/ml

0.06

Postmenopausal atrophic vaginitis

162

712

1.37

3.49

1.1

1.57

2.95

u/ml

1.47

304

Parodontitis or operation codes

604

5187

0.86

3.47

1.1

3.56

4.63

u/ml

1.29

309

2546

Parodontitis

603

5183

0.86

3.47

1.1

3.57

4.63

u/ml

1.27

308

2543

Diseases of appendix

809

6451

1.15

3.47

1.1

4.53

5.25

u/ml

0.71

406

3274

Drug-induced adrenocortical insufficiency

2.39

3.45

1.1

0.30

7.73

u/ml

—

Adenomyosis (Endometriosis of uterus)

108

747

1.45

3.44

1.1

2.04

4.63

u/ml

2.36

352

Secondary malignant neoplasm of respiratory and digestive organs, excluding all cancers (controls excluding all cancers)

570

0.51

3.43

1.0

1.1

7.43

3.63

u/ml

—

260

Chronic periodontitis, including avohilmo

600

5173

0.86

3.43

1.1

3.58

4.63

u/ml

1.25

307

2538

Flat foot [pes planus] (acquired)

529

1.54

3.42

1.1

3.46

4.87

u/ml

0.56

249

Other diseases of intestines

1315

6871

1.11

3.42

1.1

5.04

5.71

u/ml

0.66

658

3695

Substance use, excluding alcohol

132

1815

0.72

3.40

1.1

6.79

6.85

u/ml

0.01

972

Other arthrosis

399

2356

1.21

3.39

1.1

2.35

4.16

u/ml

2.59

201

1063

Contracture of joint

3.15

3.39

1.0

1.1

16.45

11.41

u/ml

—

Unspecific neurodegenerative disorder

431

0.53

3.39

1.0

1.23

2.25

u/ml

0.49

180

Disorders of refraction and accommodation

349

2848

1.23

3.38

1.1

3.52

6.34

u/ml

4.35

191

1618

Idiopathic pulmonary fibrosis

140

2.08

3.37

1.0

1.1

4.76

3.38

u/ml

0.12

Exclusions for E4_PCOS_CONSORTIUM

742

5334

0.87

3.37

1.1

3.97

5.53

u/ml

2.16

345

2802

Other/unspecified enthesopathies, not elsewhere classified

397

1.62

3.36

1.3

1.1

6.21

5.06

u/ml

0.18

176

Obsessive-compulsive disorder

115

811

1.44

3.36

1.1

4.72

6.96

u/ml

0.97

463

Other/unspecified enthesopathies of lower limb, excluding foot

476

1.57

3.36

1.1

4.22

5.56

u/ml

0.43

234

Nontoxic goitre/thyroid nodule

190

1448

1.32

3.35

1.1

3.99

3.81

u/ml

0.05

674

Erysipelas

241

2782

0.79

3.34

1.0

1.1

4.93

4.47

u/ml

0.18

129

1361

Other viral hepatitis

587

0.52

3.32

1.2

1.1

3.97

7.14

u/ml

0.80

307

Sub-endpoint used in defining T1D endpoints

208

2629

0.78

3.32

1.0

1.1

6.79

6.37

u/ml

0.12

122

1498

Uterine polyps

509

1.54

3.31

1.0

1.1

2.54

3.88

u/ml

0.73

243

Excessive attrition of teeth

504

2306

1.19

3.31

1.1

5.85

6.11

u/ml

0.13

282

1217

Benign neoplasm: Choroid

197

1.89

3.30

1.1

1.0

5.95

4.60

u/ml

0.16

Sexual dysfunction

2.39

3.28

1.0

1.1

2.19

6.56

u/ml

—

Benign neoplasm: Sigmoid colon

582

1.50

3.28

1.0

1.1

2.41

3.00

u/ml

0.23

263

Other specified/unspecified bacterial intestinal infections

293

1.72

3.27

1.1

2.93

6.61

u/ml

1.60

155

Polyarthrosis

102

675

1.45

3.27

1.1

1.0

1.03

3.24

u/ml

3.03

264

Major coronary heart disease event

242

2043

0.79

3.26

1.1

2.16

3.32

u/ml

1.23

102

956

L04AD Calcineurin inhibitors

887

0.62

3.25

1.1

6.06

5.92

u/ml

0.02

521

Nephropathy related operations

662

0.56

3.25

1.1

5.81

5.11

u/ml

0.10

364

Dental operations

609

2677

1.17

3.25

1.1

4.67

4.74

u/ml

0.03

315

1339

Pulmonary embolism

152

1126

1.35

3.25

1.0

1.1

3.59

4.19

u/ml

0.23

532

Acute appendicitis

764

6319

1.14

3.24

1.1

4.57

5.28

u/ml

0.66

384

3211

Other and unspecified trigeminal disorders

2.55

3.24

1.0

1.75

5.96

u/ml

—

Disorders of sclera, cornea, iris and ciliary body

508

4324

1.18

3.24

1.1

6.50

5.35

u/ml

0.70

282

2223

Other deformities of toe(s)

136

2.08

3.23

1.0

1.1

0.36

5.71

u/ml

2.10

Injuries to the neck

262

2093

1.26

3.22

1.1

6.58

6.39

u/ml

0.06

145

1127

Pulmonary heart disease

152

1129

1.35

3.20

1.0

1.1

3.59

4.16

u/ml

0.22

535

Benign neoplasm: Small intestine

110

2.20

3.20

1.2

1.0

0.99

3.66

u/ml

1.68

ILD, hospital admissions 3, with pneumonia sepsis

178

1.92

3.19

1.1

6.61

4.31

u/ml

0.30

Special screening examination for neoplasms

117

2.15

3.16

1.0

1.91

4.05

u/ml

0.53

Diseases of male genital organs

506

2164

1.19

3.16

1.1

6.27

6.76

u/ml

0.23

289

1269

Hypothyroidism, strict autoimmune, 3 medication purchases required

884

5331

1.13

3.16

1.1

4.31

5.22

u/ml

1.04

418

2683

Deforming dorsopathies

260

2081

1.25

3.14

1.1

7.66

5.89

u/ml

0.59

134

1092

Benign neoplasm: Stomach

327

1.66

3.14

1.1

4.49

3.37

u/ml

0.22

148

Explicit Sepsis

205

2512

0.78

3.14

1.1

7.03

5.42

u/ml

0.53

118

1349

malignant neoplasm of male genital organs

696

0.66

3.14

1.0

1.1

5.87

3.73

u/ml

0.28

324

Insulin, intermediate and long-acting

302

3625

0.81

3.14

1.0

1.1

6.52

5.40

u/ml

0.44

156

1953

Blepharochalasis

131

955

1.38

3.12

1.1

3.44

2.51

u/ml

0.38

402

Other/unspecified soft tissue disorders related to use, overuse and pressure

159

1.98

3.11

1.1

6.50

6.65

u/ml

0.02

Spondylosis

345

2437

1.22

3.11

1.1

3.13

3.67

u/ml

0.31

162

1107

Meniscus derangement

480

2784

1.18

3.08

1.1

3.27

4.50

u/ml

1.80

238

1311

Disorders of parathyroid gland

103

713

1.43

3.07

1.1

2.16

4.23

u/ml

1.26

340

Myotonic disorders

2.98

3.06

1.3

1.0

9.96

6.07

u/ml

—

Other otitis externa (chronic)

400

1.59

3.06

1.0

1.1

7.58

5.88

u/ml

0.27

221

Endocrine, nutritional and metabolic diseases

1230

5639

1.11

3.06

1.1

6.19

6.22

u/ml

0.02

641

3083

Type 1 diabetes, wide definition

185

2380

0.77

3.05

1.1

7.63

6.44

u/ml

0.37

113

1381

Secondary and unspecified malignant neoplasm of lymph nodes, excluding all cancers (controls excluding all cancers)

585

0.54

3.04

1.1

3.83

3.68

u/ml

0.02

284

Short Achilles tendon (acquired)

126

2.09

3.04

1.1

2.74

6.41

u/ml

0.69

Viral hepatitis

634

0.56

3.04

1.2

1.1

3.78

6.76

u/ml

0.79

330

Dysplasia of cervi uteri

308

1945

1.23

3.03

1.1

5.32

5.14

u/ml

0.07

145

981

Other diseases of intestine

416

1.57

3.03

1.1

4.39

4.04

u/ml

0.08

208

Implicit Sepsis

434

3985

0.84

3.02

1.1

4.97

4.88

u/ml

0.04

238

2042

Other and unspecified mental retardation

321

0.39

3.01

1.2

0.90

5.50

u/ml

—

252

Other disorders of the musculoskeletal system and connective tissue

668

1.44

3.01

1.1

3.32

4.48

u/ml

0.39

312

Malignant neoplasm of eye, brain and central nervous system, excluding all cancers (controls excluding all cancers)

382

0.44

3.00

1.2

1.1

4.48

5.00

u/ml

—

208

Extrapyramidal and movement disorders

214

1684

1.27

2.99

1.1

5.18

4.93

u/ml

0.08

823

Inflammation of lacrimal passages (acute and unspecified)

2.44

2.99

1.2

1.0

0.53

2.57

u/ml

—

Systemic connective tissue disorders

260

2094

1.25

2.99

1.1

5.87

4.66

u/ml

0.48

130

1034

Superficial injury of lower leg

260

2096

1.25

2.98

1.1

6.59

6.78

u/ml

0.05

136

1139

Oral leukoplakia and related diseases, including avohilmo

348

1.62

2.96

1.1

1.12

4.62

u/ml

3.40

167

Complications of medical and surgical care

622

5140

1.15

2.96

1.1

4.21

4.70

u/ml

0.33

319

2561

Other diseases of stomach and duodenum

212

1.80

2.96

1.2

1.1

4.43

5.50

u/ml

0.19

107

Reimbursement for rheumatic diseases

379

4501

0.84

2.96

1.1

4.59

5.00

u/ml

0.18

186

2298

Other predominantly sexually transmitted diseases, not elsewhere classified

248

1993

1.25

2.95

1.1

5.17

6.00

u/ml

0.37

133

1077

Impetigo

518

1.51

2.93

1.2

1.1

5.70

6.06

u/ml

0.07

322

Appendectomy

731

6203

1.14

2.93

1.1

4.65

5.41

u/ml

0.72

383

3150

Alcohol withdrawal state with delirium

279

0.36

2.93

1.0

1.1

1.86

5.11

u/ml

—

129

Obesity due to excess calories

489

4190

1.17

2.92

1.1

4.14

5.29

u/ml

1.12

252

2153

Major anomalies of jaw size

214

1.80

2.91

1.0

1.1

8.65

8.46

u/ml

0.02

121

Benign neoplasm: Choroid

206

1.81

2.91

1.1

1.0

5.95

4.37

u/ml

0.20

100

Otitis media, unspecified

210

1526

1.28

2.91

1.2

1.1

6.43

7.35

u/ml

0.34

135

948

Other complications of surgical and medical care, not elsewhere classified

616

1.45

2.90

1.1

2.75

5.38

u/ml

1.84

314

Anosmia

2.23

2.89

1.1

0.86

3.13

u/ml

—

Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism

801

6472

0.89

2.89

1.1

5.70

4.95

u/ml

0.45

441

3346

Persons with potential health hazards related to socioeconomic and psychosocial circumstances

443

3731

1.18

2.88

1.1

4.04

6.09

u/ml

3.05

267

2090

Deep bite that required surgery

2.34

2.88

1.0

1.1

9.04

5.39

u/ml

—

Nonorganic sleeping disorders, excluding more controls

217

1722

1.27

2.88

1.1

6.00

6.05

u/ml

0.01

128

915

Fever of other and unknown origin

537

4298

1.16

2.88

1.1

4.85

6.11

u/ml

1.14

299

2275

Endometriosis

413

2068

1.19

2.86

1.1

3.93

5.16

u/ml

1.09

204

1047

Other inflammation of vagina/vulva

361

1.60

2.85

1.1

4.84

5.48

u/ml

0.11

188

Other disorders of teeth and supporting structures

160

1222

1.31

2.85

1.1

3.41

5.31

u/ml

1.19

620

Falls/tendency to fall

1435

6551

1.10

2.84

1.1

5.61

5.74

u/ml

0.10

780

3437

Polyuria

132

981

1.35

2.83

1.1

4.72

4.48

u/ml

0.05

489

Gluteal tendinitis

172

1.88

2.83

1.0

1.1

2.87

3.43

u/ml

0.11

Certain infectious and parasitic diseases

1278

5804

1.10

2.82

1.1

5.99

5.81

u/ml

0.11

684

3029

Chronic crepitant synovitis/bursitis of hand and wrist/periarthritis of wrist

2.51

2.81

1.1

1.0

4.43

5.37

u/ml

—

Other symptoms and signs involving the circulatory and respiratory systems

322

1.63

2.81

1.1

1.0

8.13

6.38

u/ml

0.19

172

Other acquired deformities of musculoskeletal system and connective tissue

246

1.72

2.81

1.1

4.02

5.40

u/ml

0.25

129

Benign neoplasm: Duodenum

2.49

2.80

1.3

1.0

1.08

4.74

u/ml

—

Benign neoplasm: Duodenum

2.49

2.80

1.3

1.0

1.08

4.39

u/ml

—

Benign neoplasm: Stomach

338

1.61

2.79

1.1

4.49

3.56

u/ml

0.18

165

Other diseases of peritoneum

202

1.80

2.78

1.0

4.20

4.63

u/ml

0.06

Other and unspecified follicular disorders

232

1.74

2.78

1.1

2.79

6.62

u/ml

1.27

121

Pericarditis

131

2.00

2.76

1.2

1.0

3.08

6.46

u/ml

0.90

Malignant neoplasm of digestive organs

1074

0.69

2.74

1.0

7.19

3.60

u/ml

0.58

483

Type 1 diabetes

210

2621

0.80

2.73

1.0

1.1

6.68

6.27

u/ml

0.12

124

1521

Patellar tendinitis

132

2.01

2.73

1.1

7.51

7.71

u/ml

0.01

Spinal osteochondrosis

2.65

2.73

1.1

6.39

11.63

u/ml

—

Use of anticholinesterases

343

0.49

2.73

1.0

0.57

2.07

u/ml

—

141

N06DA Anticholinesterases

343

0.49

2.73

1.0

0.57

2.07

u/ml

—

141

Other puerperal infections

130

973

1.35

2.73

1.1

5.34

5.92

u/ml

0.22

523

Deep bite

192

1323

1.28

2.72

1.1

7.34

7.42

u/ml

0.02

115

835

Galactorrhea

2.34

2.72

1.1

6.54

4.33

u/ml

0.26

Suppurative otitis media, unspecified

219

1.76

2.71

1.0

1.1

5.58

7.88

u/ml

0.31

135

Disorders of choroid and retina

416

3556

0.85

2.71

1.1

5.45

4.80

u/ml

0.21

209

1736

Other retinal artery occlusion

3.00

2.70

1.0

1.1

0.29

3.34

u/ml

—

Defects in the complement system

2.48

2.69

1.2

1.1

5.77

5.91

u/ml

—

Disorders of eyelid in diseases classified elsewhere

168

1.87

2.69

1.1

10.67

4.88

u/ml

0.75

Coronary angioplasty

873

0.69

2.68

1.1

1.0

1.86

3.37

u/ml

1.03

397

Insulin, fast-acting (human)

101

1387

0.72

2.68

1.0

1.1

6.21

6.87

u/ml

0.17

770

Pre-eclampsia or poor fetal growth

294

3531

0.83

2.68

1.1

3.61

5.02

u/ml

0.95

142

1768

Dislocation, sprain and strain of joints and ligaments at ankle and foot level

506

4376

1.16

2.67

1.1

6.11

6.67

u/ml

0.33

294

2376

Other infective otitis externa

335

1.60

2.66

1.0

1.1

4.59

4.74

u/ml

0.02

178

Inflammatory disorders of breast

571

1.45

2.64

1.1

5.55

6.10

u/ml

0.14

296

Degenerative diseases of the nervous system

394

0.55

2.63

1.0

1.21

3.36

u/ml

1.18

169

Tramadol

749

4268

1.13

2.63

1.1

3.49

4.81

u/ml

2.24

383

2134

Alzheimer disease, including avohilmo

331

0.52

2.63

1.0

1.45

1.72

u/ml

—

136

Cholecystectomy

545

4195

1.15

2.62

1.1

3.96

4.05

u/ml

0.04

245

1988

Malignant neoplasm of breast, HER-positive

128

1669

0.75

2.62

1.1

2.88

2.76

u/ml

0.04

709

Other diseases of anus and rectum

193

1527

1.27

2.62

1.1

5.67

4.97

u/ml

0.23

776

Sulfonylureas

674

0.65

2.61

1.0

1.1

1.08

3.10

u/ml

2.20

311

Type 1 diabetes, wide definition, subgroup 1

181

2283

0.79

2.60

1.0

1.1

7.04

6.52

u/ml

0.14

110

1316

Atherosclerosis, excluding cerebral and coronary sclerosis

789

0.68

2.60

1.1

1.0

4.87

2.85

u/ml

0.33

351

Thyroiditis, unspecified

2.22

2.60

1.0

1.1

5.02

5.20

u/ml

—

Candidiasis

121

902

1.35

2.59

1.1

3.06

5.79

u/ml

1.36

478

Benign neoplasm of eye and adnexa

425

1.51

2.59

1.1

4.13

4.55

u/ml

0.07

211

Benign neoplasm of eye and adnexa

425

1.51

2.59

1.1

4.13

4.52

u/ml

0.07

220

Impacted maxillary canine

136

1.99

2.59

1.0

1.1

4.17

9.07

u/ml

1.51

Other disorders of bone

209

1675

1.25

2.58

1.1

5.83

6.17

u/ml

0.10

115

877

Coeliac disease

131

989

1.33

2.58

1.1

5.79

6.18

u/ml

0.08

545

Lateral epicondylitis

115

851

1.36

2.58

1.2

1.1

5.01

4.83

u/ml

0.04

390

Superficial injury of wrist and hand

248

2026

1.23

2.58

1.1

4.87

6.43

u/ml

0.90

141

1143

Premenstrual syndrome

101

2.13

2.57

1.0

1.1

1.83

5.13

u/ml

—

Oligomenorrhoea

339

1.58

2.57

1.0

1.1

3.78

6.49

u/ml

1.36

188

Other specified/unspecified soft tissue disorders

178

1.81

2.56

1.1

7.69

5.57

u/ml

0.22

Covid-19 confirmed case

259

2126

1.22

2.55

1.1

5.52

5.97

u/ml

0.17

144

1151

Benign neoplasm: Ascending colon

354

1.56

2.55

1.1

3.73

3.69

u/ml

0.01

161

Synovial cyst of popliteal space [Baker]

253

1.67

2.55

1.1

1.37

5.17

u/ml

2.81

123

Vulvovaginal ulceration/inflammation in other diseases

601

1.43

2.54

1.1

6.88

5.85

u/ml

0.19

319

Persistent mood disorders

178

1403

1.27

2.54

1.1

4.90

5.83

u/ml

0.40

712

Drug-induced cataract

108

2.07

2.53

1.2

1.0

2.26

7.20

u/ml

1.53

Other specified/unspecified disorders of synovium and tendon +Other specified/unspecified bursopathies

332

1.58

2.53

1.1

3.44

6.35

u/ml

0.74

172

Viral infections characterized by skin and mucous membrane lesions

411

3518

1.17

2.53

1.1

6.53

5.42

u/ml

0.59

229

1930

Malignant neoplasm of prostate, excluding all cancers (controls excluding all cancers)

548

0.67

2.52

1.0

1.1

6.25

3.20

u/ml

0.34

241

Endometriosis of pelvic peritoneum

193

1518

1.26

2.51

1.1

4.24

5.16

u/ml

0.43

766

Pulmonary heart disease, diseases of pulmonary circulation

162

1263

1.29

2.50

1.0

1.1

3.40

4.47

u/ml

0.52

615

Kidney transplant status

367

0.49

2.50

1.2

1.1

4.93

6.81

u/ml

—

220

Benign neoplasm: Ascending colon

356

1.55

2.50

1.1

3.73

3.87

u/ml

0.03

169

L04AA Selective immunosuppressants

129

1690

0.76

2.50

1.0

1.1

4.48

5.94

u/ml

0.66

890

Rheumatism, unspecified

100

728

1.38

2.49

1.1

2.15

3.91

u/ml

1.51

335

Type 1 diabetes, strict (exclude DM2)

113

1500

0.75

2.49

1.1

6.79

7.41

u/ml

0.14

928

Delivery

357

2232

0.84

2.48

1.1

5.06

6.27

u/ml

0.74

196

1184

Other specified and unspecified disorders of eye and adnexa

180

1.80

2.48

1.1

0.43

7.29

u/ml

4.78

Androgenic alopecia

2.74

2.48

1.1

1.0

1.48

2.69

u/ml

—

Biomechanical lesions, not elsewhere classified

195

1.76

2.47

1.2

1.1

2.16

5.59

u/ml

1.29

Mycoses

216

1747

1.24

2.47

1.1

4.01

5.69

u/ml

0.94

114

912

Any mental disorder

1292

5914

1.10

2.47

1.1

5.56

5.68

u/ml

0.08

698

3089

Other acute skin changes due to ultraviolet radiation

130

1.94

2.46

1.1

1.0

2.63

3.71

u/ml

0.18

Hyperparathyroidism

571

1.42

2.46

1.1

2.58

3.74

u/ml

0.47

271

Intracranial injury

555

4704

1.14

2.45

1.1

5.74

5.87

u/ml

0.05

316

2536

Diseases of arteries, arterioles and capillaries

256

2315

0.82

2.44

1.1

3.94

4.17

u/ml

0.09

113

1120

Primary_lymphoid and hematopoietic malignant neoplasms

1040

0.70

2.44

1.1

8.06

4.51

u/ml

0.58

547

Procedures for purposes other than remedying health state

131

1.93

2.42

1.1

5.40

4.46

u/ml

0.08

Generalized epilepsy, strict definition

243

1.68

2.41

1.1

1.2

4.81

6.49

u/ml

0.26

155

Peroneal tendinitis

2.15

2.41

1.0

1.1

0.84

6.57

u/ml

—

Benign neoplasm: Colon

285

1815

1.21

2.41

1.0

1.1

2.90

3.30

u/ml

0.27

138

842

Other and/or unspecified nontoxic goitre

360

1.54

2.40

1.0

2.44

3.54

u/ml

0.53

166

Panniculitis affecting regions of neck and back

197

1.74

2.40

1.1

2.23

5.38

u/ml

1.42

Other abnormal products of conception

503

2918

1.15

2.40

1.1

5.09

5.13

u/ml

0.02

245

1470

Acute alcohol intoxication

136

1759

0.77

2.40

1.1

3.94

5.95

u/ml

0.81

920

Type 1 diabetes, strict definition

102

1365

0.74

2.40

1.1

7.95

7.65

u/ml

0.05

861

Other bursopathies

573

1.42

2.40

1.0

1.1

2.75

4.44

u/ml

0.91

260

Benign neoplasm: Middle ear, nasal cavity and accessory sinuses

153

1.85

2.39

1.0

4.48

5.12

u/ml

0.10

Benign neoplasm of middle ear and respiratory system

297

1.59

2.39

1.1

4.11

4.21

u/ml

0.02

151

Cardiovascular diseases

1111

5510

1.10

2.39

1.1

6.19

6.21

u/ml

0.01

598

3089

Malignant neoplasm of breast, ER-negative, excluding all cancers (controls excluding all cancers)

1140

0.72

2.37

1.0

1.1

5.27

2.75

u/ml

0.45

516

Testicular hypofunction

183

1.77

2.37

1.1

2.89

7.61

u/ml

1.67

Type1 diabetes, definitions combined, early onset

1210

0.72

2.36

1.1

7.53

7.39

u/ml

0.03

768

Bacterial Sepsis

169

1892

0.79

2.36

1.0

1.1

5.32

4.74

u/ml

0.16

948

Use of disulfiram, acamprosate or naltrexone

601

0.61

2.35

1.1

0.97

5.32

u/ml

6.06

299

Leiomyoma of uterus

406

2661

0.86

2.35

1.1

2.71

3.66

u/ml

1.02

167

1264

Other maternal disorders predominantly related to pregnancy

733

4113

1.12

2.35

1.1

4.45

5.32

u/ml

0.88

335

2076

Atrial septal defect

520

0.58

2.35

1.0

1.2

2.91

5.72

u/ml

0.80

367

Valvular heart disease excluding rheumatic fever

206

1856

0.81

2.35

1.0

1.1

5.34

4.36

u/ml

0.32

974

Complications associated with artificial fertilization

192

1.75

2.34

1.0

1.1

1.64

7.14

u/ml

3.14

109

Examination and encounter for administrative purposes

140

1.87

2.32

1.0

1.1

5.14

8.13

u/ml

0.42

Residual foreign body in soft tissue

324

1.56

2.31

1.1

4.79

7.15

u/ml

0.54

174

Maternal care for other known or suspected fetal problems

324

2451

0.84

2.30

1.1

4.18

5.68

u/ml

0.99

153

1313

Benign neoplasm: Middle ear, nasal cavity and accessory sinuses

155

1.82

2.30

1.0

1.1

4.48

4.94

u/ml

0.07

L02BG Aromatase inhibitors

1318

0.74

2.30

1.0

1.1

1.85

3.34

u/ml

1.64

580

Benign neoplasm: Scapula and long bones of upper limb

2.51

2.30

1.1

1.0

8.24

7.97

u/ml

—

Spinal instabilities

148

1.84

2.30

1.0

1.01

5.71

u/ml

2.35

Poor fetal growth

127

1643

0.77

2.30

1.1

5.42

5.56

u/ml

0.03

877

Other spirochaetal diseases

187

1503

1.25

2.29

1.1

4.59

4.95

u/ml

0.14

745

Open wound of wrist and hand

453

3903

1.15

2.29

1.0

1.1

5.92

6.01

u/ml

0.04

234

2107

Bleeding

504

4183

0.87

2.29

1.1

5.54

5.00

u/ml

0.21

258

2144

Xerosis cutis

2.72

2.29

1.0

14.28

8.29

u/ml

—

Other and unspecified local infections of skin and subcutaneous tissue

596

1.40

2.29

1.1

6.35

4.85

u/ml

0.31

323

Urethritis and urethral syndrome

106

2.01

2.27

1.1

4.01

10.27

u/ml

1.30

Fracture at wrist and hand level

345

2945

1.17

2.25

1.1

6.68

6.37

u/ml

0.12

193

1622

Adrenocortical insufficiency

217

1.68

2.24

1.1

0.28

7.01

u/ml

5.95

127

Lichen planus

506

1.43

2.23

1.0

1.1

7.41

3.89

u/ml

0.69

236

Dislocation, sprain and strain of joints and ligaments of shoulder girdle

257

2141

1.20

2.23

1.1

4.44

6.35

u/ml

1.52

127

1136

Acute alcohol intoxication, ICD10

119

1547

0.77

2.22

1.1

4.13

6.17

u/ml

0.74

824

Other disorders of penis

625

1.38

2.22

1.1

4.00

7.20

u/ml

1.08

386

Other neurological diseases

371

3466

0.86

2.22

1.1

3.55

4.72

u/ml

0.99

191

1721

Type 1 diabetes, definitions combined

116

1506

0.76

2.22

1.1

7.44

7.36

u/ml

0.01

931

Noninfectious colitis NAS

130

1005

1.30

2.21

1.2

1.1

4.98

6.30

u/ml

0.39

549

Chronic viral hepatitis

503

0.59

2.21

1.2

1.1

3.97

6.81

u/ml

0.69

257

Type 1 diabetes, strict definition, subgroup 1

1289

0.74

2.20

1.1

6.96

7.77

u/ml

0.17

804

Hypertensive diseases

708

4473

0.89

2.20

1.1

4.77

4.72

u/ml

0.03

344

2292

Keratitis and keratoconjunctivitis in other diseases classified elsewhere

158

1.79

2.18

1.1

4.90

5.15

u/ml

0.03

Bitten or stung by nonvenomous insect and other nonvenomous arthropods

242

1.63

2.18

1.1

2.48

7.03

u/ml

2.47

145

Suicide or other Intentional self-harm

195

2387

0.81

2.17

1.1

4.13

6.02

u/ml

1.04

1259

LeFortI or BSSRO operation

378

1.50

2.17

1.1

4.20

5.57

u/ml

0.30

193

Acute renal failure

650

0.64

2.17

1.0

1.1

6.99

4.86

u/ml

0.26

333

Haemangioma, any site

535

1.41

2.17

1.1

3.65

5.17

u/ml

0.50

286

Other local infections of skin and subcutaneous tissue

628

1.38

2.16

1.1

6.09

4.97

u/ml

0.22

335

Bicipital tendinitis

196

1.70

2.16

1.1

1.0

7.40

5.29

u/ml

0.23

Acne

187

1517

1.24

2.15

1.1

7.61

8.22

u/ml

0.15

107

890

Sacrococcygeal disorders, not elsewhere classified

189

1.71

2.15

1.1

1.56

5.25

u/ml

1.86

Other shoulder lesions

629

1.38

2.14

1.1

3.34

5.48

u/ml

0.98

309

Presence of other functional implants

191

1663

0.81

2.14

1.1

4.38

3.75

u/ml

0.21

776

Contraceptive management

526

3260

1.14

2.14

1.1

5.77

5.50

u/ml

0.13

265

1668

Hypersensitivity pneumonitis due to organic dust

2.39

2.13

1.1

1.0

0.27

8.28

u/ml

—

Persistent delusional disorders

398

0.55

2.13

1.0

1.1

1.60

5.07

u/ml

1.75

200

Finngen Rheumatological endpoints

1002

6254

0.91

2.13

1.1

5.25

5.54

u/ml

0.20

516

3235

Coronary atherosclerosis

256

1973

0.84

2.12

1.0

1.1

2.86

3.07

u/ml

0.11

111

934

Non-selective monoamine reuptake inhibitors

257

2087

1.20

2.12

1.1

2.95

3.84

u/ml

0.61

145

929

Retained placenta and membranes, without haemorrhage

122

942

1.30

2.12

1.1

2.67

4.33

u/ml

1.19

455

Benign neoplasm: Skin of ear and external auricular canal

116

1.91

2.11

1.0

0.92

5.24

u/ml

—

Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity

228

1.63

2.11

1.0

2.14

4.31

u/ml

0.82

126

917

1.29

2.11

1.0

2.46

2.72

u/ml

0.09

406

Persons encountering health services in circumstances related to reproduction

767

4688

1.11

2.10

1.1

5.46

6.10

u/ml

0.51

422

2567

Chondropathies

161

1288

1.26

2.10

1.1

5.91

6.53

u/ml

0.18

669

malignant neoplasm of female genital organs, excluding all cancers (controls excluding all cancers)

809

0.69

2.10

1.0

1.1

4.30

2.46

u/ml

0.43

373

Acute generalized exanthematous pustulosis

276

1.57

2.10

1.1

5.86

6.84

u/ml

0.12

158

Carpal tunnel syndrome

479

3801

1.14

2.09

1.1

4.01

4.07

u/ml

0.03

234

1799

Medicines for HER+ breast cancer

156

1897

0.80

2.09

1.1

3.08

3.52

u/ml

0.25

837

Hypertension

709

4463

0.90

2.09

1.1

4.77

4.73

u/ml

0.02

345

2283

Redundant prepuce, phimosis and paraphimosis

186

1506

1.23

2.08

1.1

7.64

7.71

u/ml

0.02

117

881

Other disorders of adrenal gland

341

1.51

2.08

1.1

3.49

6.08

u/ml

0.95

204

Benign paroxysmal vertigo

172

1387

1.24

2.08

1.1

3.88

4.54

u/ml

0.31

661

Malignant neoplasm of respiratory system and intrathoracic organs, excluding all cancers (controls excluding all cancers)

530

0.65

2.07

1.0

1.1

9.43

3.11

u/ml

0.56

242

Iron deficiency

223

1.64

2.06

1.1

3.36

5.75

u/ml

0.64

128

Colonic or urogenital fistula

211

1741

1.22

2.06

1.1

5.11

5.43

u/ml

0.09

885

Benign neoplasm of mouth and pharynx

515

1.40

2.06

1.0

1.1

7.14

4.51

u/ml

0.61

258

Other noninflammatory disorders of vulva and perineum

677

1.35

2.05

1.0

1.1

5.93

5.64

u/ml

0.08

353

Primary_lymphoid and hematopoietic malignant neoplasms

1006

0.72

2.05

1.1

8.06

4.75

u/ml

0.53

531

Haemangioma and lymphangioma, any site

609

1.37

2.05

1.1

3.70

5.50

u/ml

0.68

330

Speech and linguistic disorders, excluding more controls

160

1211

1.26

2.04

1.1

6.62

8.58

u/ml

0.63

103

791

Certain conditions originating in the perinatal period

201

1467

1.23

2.03

1.2

1.1

6.78

7.80

u/ml

0.35

128

951

Insulin, fast-acting or short human

243

2890

0.84

2.03

1.0

1.1

7.15

6.00

u/ml

0.41

132

1612

Presence of cardiac and vascular implants and grafts

119

1159

0.78

2.02

1.0

1.1

6.27

3.55

u/ml

0.60

551

Benign neoplasm of other and unspecified female genital organs

208

1.65

2.02

1.1

8.32

2.75

u/ml

1.06

101

Disorders of vitreous body and globe

259

2127

1.19

2.02

1.0

1.1

4.54

3.77

u/ml

0.17

123

955

Autoimmune thyroiditis

133

1.83

2.02

1.0

1.1

2.09

5.44

u/ml

1.14

Other noninflammatory disorders of vagina

509

1.40

2.01

1.0

1.1

7.19

5.41

u/ml

0.35

255

Use of biperiden

259

0.46

2.01

1.0

1.1

1.96

5.27

u/ml

—

128

Fibroblastic disorders

121

940

1.29

2.00

1.1

2.01

4.21

u/ml

2.20

426

Vascular disorders of the intestines

111

1.90

2.00

1.0

4.32

4.97

u/ml

—

Parodontitis and operation codes

580

5046

0.89

2.00

1.1

3.50

4.62

u/ml

1.34

297

2473

Acute otitis externa, noninfective

2.17

2.00

1.1

1.0

2.83

4.57

u/ml

—

Adhesive capsulitis of shoulder

102

775

1.32

1.99

1.1

4.66

4.00

u/ml

0.10

344

Scleritis and episcleritis

394

1.46

1.98

1.1

4.56

4.62

u/ml

0.01

197

Benign neoplasm of middle ear and respiratory system

312

1.51

1.98

1.1

4.11

4.72

u/ml

0.13

159

Haemangioma and lymphangioma, any site

613

1.36

1.98

1.1

3.70

5.62

u/ml

0.74

338

Lyme disease

180

1469

1.23

1.97

1.1

4.14

4.80

u/ml

0.31

722

Ulcerative colitis (strict definition, all Crohn cases excluded)

100

1305

0.76

1.97

1.1

7.23

6.81

u/ml

0.07

700

Mucosal proctocolitis

1134

0.75

1.96

1.1

6.69

6.72

u/ml

0.01

604

Glucosamine medication

188

1226

1.23

1.96

1.1

1.0

2.92

2.29

u/ml

0.23

519

Toxic effect of contact with venomous animals

265

1.56

1.96

1.1

5.43

7.68

u/ml

0.37

147

Congenital malformations of the musculoskeletal system, not elsewhere classified

157

1.76

1.96

1.1

9.95

5.69

u/ml

0.45

Severe mental retardation

0.00

1.96

0.0

1.1

—

7.64

—

Disorders of vitreous body

250

2062

1.19

1.95

1.0

1.1

4.37

3.81

u/ml

0.12

118

927

Insulin, fast-acting

243

2877

0.84

1.94

1.0

1.1

7.15

5.99

u/ml

0.41

132

1613

Nontoxic single thyroid nodule

379

1.46

1.94

1.1

6.05

4.67

u/ml

0.17

186

Pedestrian injured in other and unspecified transport accidents

2.48

1.94

1.2

1.1

1.00

7.12

u/ml

—

Benign intracranial hypertension

1.97

1.94

1.1

3.32

6.12

u/ml

—

Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure

435

3824

1.14

1.94

1.1

4.20

4.69

u/ml

0.27

224

1880

Nausea and vomiting

242

2002

1.19

1.94

1.1

5.33

5.97

u/ml

0.29

135

1139

Abnormal findings on diagnostic imaging of central nervous system

282

1.54

1.93

1.1

4.70

4.57

u/ml

0.02

152

Benign neoplasm: Skin of ear and external auricular canal

120

1.85

1.93

1.0

0.92

5.07

u/ml

—

Behavioural syndromes associated with physiological disturbances and physical factors

422

3706

1.14

1.93

1.1

5.86

6.49

u/ml

0.30

239

2031

Non-rheumatic valve diseases

202

1779

0.83

1.92

1.0

1.1

5.47

4.30

u/ml

0.39

918

Haemangioma, any site

548

1.38

1.92

1.1

3.65

5.53

u/ml

0.66

298

Pain associated with micturition

711

1.33

1.92

1.1

7.80

5.74

u/ml

0.27

384

Second line medication for Crohn's disease

439

4973

0.88

1.92

1.1

5.00

5.52

u/ml

0.29

228

2635

Haemorrhoids and perianal venous thrombosis

155

1249

1.24

1.90

1.0

1.1

4.75

4.28

u/ml

0.13

615

Testicular dysfunction

204

1.63

1.90

1.1

2.89

7.07

u/ml

1.53

106

Other factor of the environment

2.19

1.90

1.0

1.48

9.60

u/ml

—

Injury of muscle and tendon at lower leg level

114

887

1.29

1.90

1.1

2.67

5.58

u/ml

2.74

452

Viral pneumonia (unknown virus, not influenza)

448

1.42

1.89

1.1

8.30

6.25

u/ml

0.32

244

Seborrhoeic keratosis

100

764

1.31

1.89

1.1

1.0

2.81

3.71

u/ml

0.36

332

Disorders of gallbladder, biliary tract and pancreas

728

5176

0.90

1.89

1.1

3.56

4.50

u/ml

1.04

338

2558

Lichen planus, including avohilmo

107

826

1.30

1.89

1.0

1.1

6.13

4.03

u/ml

0.50

383

150

1.73

1.88

1.0

4.75

7.68

u/ml

0.67

Campylobacter enteritis

136

1.78

1.88

1.1

0.31

6.35

u/ml

3.84

Mental and behavioural disorders due to sedatives or hypnotics

542

0.64

1.88

1.0

1.1

6.87

5.93

u/ml

0.10

286

Alzheimer disease, excluding more controls

197

0.51

1.88

1.0

2.54

1.97

u/ml

—

Mental and behavioural disorders due to cannabinoids

355

0.56

1.88

1.1

1.38

7.64

u/ml

6.11

210

Exposure to other and unspecified inanimate mechanical forces

568

1.37

1.87

1.1

4.68

6.19

u/ml

0.49

317

Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances

142

1763

0.80

1.87

1.1

4.63

6.40

u/ml

0.62

962

Other superficial mycoses

129

1.81

1.87

1.1

1.91

7.80

u/ml

2.05

Other sleep disorders

688

1.33

1.87

1.1

4.65

6.08

u/ml

0.37

353

Injury of muscle and tendon at ankle and foot level

159

1.72

1.87

1.0

1.1

3.43

6.44

u/ml

0.74

Cholecystitis

474

1.40

1.86

1.1

6.66

3.73

u/ml

0.42

225

Mixed conductive and sensorineural hearing loss

441

1.41

1.85

1.0

0.83

4.40

u/ml

5.28

228

Generalized skin eruption due to drugs and medicaments

253

1.56

1.85

1.1

6.31

7.36

u/ml

0.12

145

Struck by thrown, projected or falling objec

367

1.46

1.85

1.1

4.60

7.18

u/ml

0.62

211

Benign neoplasm: Skin of eyelid, including canthus

620

1.34

1.85

1.0

1.1

3.07

4.42

u/ml

0.49

296

Benign neoplasms

1204

6224

1.08

1.84

1.1

5.20

6.09

u/ml

1.11

618

3291

Perforation of tympanic membrane

673

1.33

1.84

1.1

4.35

5.75

u/ml

0.44

366

Fasciculation

2.16

1.84

1.0

2.97

6.55

u/ml

—

Lichen ruber planus, wide definition including periferal and oral lichen planus

127

1006

1.27

1.84

1.0

1.1

5.57

4.07

u/ml

0.38

474

Mild mental retardation

275

0.50

1.84

1.1

1.2

0.11

7.93

u/ml

—

180

Polyarteritis nodosa and related conditions

2.15

1.83

1.3

1.1

9.42

4.05

u/ml

—

Major coronary heart disease event excluding revascularizations

215

1772

0.84

1.83

1.0

2.20

3.13

u/ml

0.80

808

Budesonide

120

945

1.28

1.83

1.1

6.95

6.65

u/ml

0.06

472

Benign neoplasm of other and unspecified female genital organs

214

1.60

1.83

1.1

8.32

2.97

u/ml

1.00

114

Autonomic disorders

108

1.87

1.83

1.1

1.0

5.26

9.03

u/ml

0.63

Contusion of toe(s) with damage to nail

2.10

1.83

1.1

14.41

7.54

u/ml

—

Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified

711

5102

0.91

1.82

1.1

4.46

4.39

u/ml

0.04

342

2492

Spirochaetal infections, other/unspecified

401

1.43

1.82

1.1

3.65

4.40

u/ml

0.20

211

Superficial injury of shoulder and upper arm

103

796

1.30

1.82

1.1

2.66

6.25

u/ml

2.57

419

Disease of hard tissues of teeth, NOS

2.30

1.82

1.5

1.1

2.38

3.27

u/ml

—

Diseases of pulp and periapical tissues

301

2594

1.16

1.82

1.1

4.29

5.35

u/ml

0.57

160

1298

Faecal incontinence

302

1.50

1.82

1.1

1.0

2.03

2.72

u/ml

0.27

146

Localized swelling, mass and lump of skin and subcutaneous tissue

250

2123

1.18

1.82

1.1

6.49

5.38

u/ml

0.24

133

1104

Unspecified event, undetermined intent

168

1.69

1.82

1.3

1.1

6.41

7.07

u/ml

0.10

Chronic kidney disease

991

0.74

1.82

1.1

4.37

4.72

u/ml

0.06

526

Syncope and collapse

323

2477

1.16

1.81

1.1

4.65

5.79

u/ml

0.73

176

1284

Congenital absence, atresia and stenosis of large intestine

0.00

1.81

0.0

1.2

—

11.53

—

Inflammatory disease of cervix uteri

311

1.49

1.81

1.1

2.23

2.51

u/ml

0.13

140

Tobacco use

336

1.47

1.80

1.0

1.1

9.73

6.79

u/ml

0.40

165

Burn and corrosion confined to eye and adnexa

161

1.70

1.80

1.1

13.62

7.30

u/ml

0.35

Benign neoplasm: Scapula and long bones of upper limb

2.21

1.80

1.1

1.0

8.24

7.54

u/ml

—

Benign mammary dysplasia

710

1.31

1.80

1.1

3.44

3.81

u/ml

0.11

331

Melanocytic naevi

278

2385

1.17

1.79

1.1

6.48

5.67

u/ml

0.32

153

1238

Secondary uncertain malignant neoplasm

414

0.60

1.79

1.1

4.80

3.95

u/ml

0.12

200

Atrial fibrillation and flutter

193

1515

0.83

1.78

1.0

1.1

3.37

4.11

u/ml

0.43

736

Helminthiases

1.92

1.77

1.1

1.06

5.36

u/ml

—

Disturbances of smell and taste

177

1.65

1.77

1.1

1.0

0.93

4.21

u/ml

2.73

Unspecified/other endometriosis

123

978

1.27

1.76

1.1

5.75

5.60

u/ml

0.04

507

Complications of procedures, not elsewhere classified

732

5760

1.10

1.76

1.1

4.85

4.78

u/ml

0.04

377

2860

Anogenital herpesviral [herpes simplex] infection

653

1.33

1.76

1.1

3.33

6.49

u/ml

2.98

357

Puerperal sepsis

107

836

1.29

1.75

1.1

2.44

4.49

u/ml

2.37

390

Palmar fascial fibromatosis [Dupuytren]

379

1.43

1.75

1.0

1.46

3.47

u/ml

1.84

169

Colorectal neuroendocrine tumor and carcinoma

2.25

1.75

1.0

23.21

8.23

u/ml

—

Diabetic nephropathy, excluding more controls

486

0.67

1.75

1.0

1.1

7.88

4.30

u/ml

0.63

223

Persons encountering health services in other circumstances

396

3489

1.14

1.75

1.1

6.03

6.40

u/ml

0.15

200

1854

Benign neoplasm of mouth and pharynx

532

1.36

1.74

1.0

1.1

7.14

4.95

u/ml

0.48

268

Malignant neoplasm of head and neck, excluding all cancers (controls excluding all cancers)

310

0.55

1.74

1.0

1.1

0.54

3.68

u/ml

—

143

Other diseases of liver

134

1077

1.25

1.73

1.1

4.06

4.56

u/ml

0.20

531

Alcoholic liver disease

335

0.57

1.73

1.1

1.18

4.52

u/ml

—

155

Haemorrhage in early pregnancy

330

2807

1.15

1.73

1.1

3.86

4.87

u/ml

0.75

148

1433

Hernia of abdominal wall

310

2690

1.15

1.73

1.1

5.68

4.54

u/ml

0.50

162

1342

Invasive ventilation

421

0.61

1.72

1.1

1.04

5.12

u/ml

4.36

255

Ulcerative colitis (strict definition, require KELA)

123

1534

0.80

1.72

1.1

7.32

6.46

u/ml

0.19

826

Congenital malformations and deformations of the musculoskeletal system

155

1263

1.23

1.72

1.1

7.31

6.19

u/ml

0.33

794

Other orthopaedic follow-up care

274

1.51

1.71

1.1

4.22

4.96

u/ml

0.10

134

Disorders of orbit

258

1.52

1.71

1.0

1.1

1.62

5.05

u/ml

3.14

138

Other bursitis of knee

2.09

1.71

1.0

1.27

11.60

u/ml

—

Leiomyoma of uterus

473

3020

0.89

1.71

1.1

2.46

3.62

u/ml

1.65

193

1414

Spinal stenosis

235

1561

1.18

1.71

1.1

2.00

3.30

u/ml

1.44

112

674

Other diseases of jaws

399

1.41

1.69

1.0

1.1

3.87

4.79

u/ml

0.23

201

Emotional disorders starting during childhood or adolecense, excluding more controls

108

834

1.28

1.69

1.1

6.23

9.26

u/ml

1.13

552

Antihypertensive medication - note that there are other indications

1047

5298

1.08

1.69

1.1

5.26

6.62

u/ml

1.83

555

2941

Colorectal neuroendocrine tumor and carcinoma, excluding all cancers (controls excluding all cancers)

2.21

1.68

1.0

23.21

7.13

u/ml

—

Bilateral sagittal split ramus osteotomy operation

309

1.47

1.67

1.0

1.1

4.04

6.25

u/ml

0.41

159

Psychiatric diseases

1268

5913

1.08

1.67

1.1

5.61

5.67

u/ml

0.04

688

3089

Burns and corrosions confined to eye and internal organs

188

1.61

1.67

1.1

12.02

6.96

u/ml

0.31

Lifestyle-related condition

2.13

1.67

1.0

1.48

8.23

u/ml

—

Alzheimer disease

270

0.59

1.67

1.0

1.82

1.50

u/ml

—

106

Hallux rigidus

519

1.35

1.67

1.1

1.0

2.49

3.13

u/ml

0.19

215

Nontoxic multinodular goitre

110

869

1.27

1.66

1.1

3.48

3.72

u/ml

0.06

400

Respiratory insufficiency

104

1.83

1.66

1.1

1.0

0.96

3.41

u/ml

—

Cerebral cysts

435

1.39

1.66

1.1

2.74

6.24

u/ml

2.53

243

Implicit bacterial Sepsis

129

1463

0.81

1.66

1.0

1.1

4.59

4.33

u/ml

0.06

711

Otitis externa, unspecified

111

879

1.27

1.66

1.1

6.42

6.21

u/ml

0.04

483

UC patients in KELA-register ( KELA 208 prior to 1994, or ICD K51)

134

1648

0.81

1.66

1.1

7.58

6.45

u/ml

0.27

892

Ulcer of vagina/vulva

173

1.64

1.65

1.1

13.31

3.89

u/ml

0.81

Postdysenteric arthropathy

2.29

1.65

1.1

1.0

2.79

8.14

u/ml

—

Calculus of kidney and ureter

179

1491

1.20

1.65

1.1

4.81

5.17

u/ml

0.10

739

Agranulocytosis

620

0.69

1.65

1.2

1.1

3.40

4.82

u/ml

0.43

329

Dialysis

252

0.51

1.65

1.3

1.1

0.60

6.86

u/ml

—

153

Pregnancy, childbirth and the puerperium

278

1686

0.86

1.64

1.0

1.1

4.78

7.02

u/ml

1.66

146

916

Cholera

127

1.74

1.64

1.0

1.1

3.49

1.51

u/ml

—

Sequelae of external causes of morbidity and mortality

164

1356

1.21

1.64

1.1

4.51

5.04

u/ml

0.18

101

689

Early lumbar disc prolapse, operated

130

1051

1.24

1.63

1.1

4.47

6.01

u/ml

0.69

540

Other erythematous conditions

158

1.66

1.63

1.1

1.25

5.72

u/ml

2.52

Heart failure, strict

160

1394

0.82

1.63

1.0

1.1

4.97

3.13

u/ml

0.52

669

Dislocation, sprain and strain of joint and ligaments of hip

120

1.76

1.62

1.1

13.26

8.71

u/ml

0.34

Fracture of femur

725

0.73

1.62

1.0

1.1

2.18

4.79

u/ml

2.25

376

Heart failure,strict

156

1365

0.82

1.62

1.0

1.1

5.12

3.07

u/ml

0.58

660

Leiomyosarcoma

3.62

1.62

1.0

—

1.57

—

Ulcerative colitis (strict definition, require KELA, min 2 HDR)

120

1489

0.80

1.62

1.1

7.32

6.35

u/ml

0.22

807

Diseases of tongue

286

1.48

1.62

1.0

1.1

6.27

4.62

u/ml

0.22

138

Acute lymphadenitis

566

1.34

1.62

1.1

3.71

6.08

u/ml

1.17

310

Other/unspecified rheumatoid arthritis

463

0.65

1.62

1.1

1.30

3.70

u/ml

2.57

220

Drug-induced neutropenia

302

0.56

1.61

1.1

5.02

3.88

u/ml

—

148

Osteopathies and chondropathies

422

3562

1.13

1.61

1.1

6.01

5.33

u/ml

0.32

227

1813

Statin medication

666

4102

0.91

1.61

1.1

4.36

4.87

u/ml

0.40

317

2110

Demyelinating diseases of the central nervous system

790

0.73

1.61

1.0

1.1

4.69

5.49

u/ml

0.15

419

Convergence insufficiency and excess

121

1.77

1.60

1.2

1.1

0.68

6.99

u/ml

3.31

Hyperlipidaemia, other/unspecified

164

1285

1.21

1.60

1.0

1.1

2.45

3.36

u/ml

0.45

608

Other skin changes

103

812

1.27

1.59

1.1

5.19

4.94

u/ml

0.05

412

Unknown and unspecified causes of morbidity

438

1.38

1.59

1.2

1.1

5.93

6.78

u/ml

0.14

231

Infective bursitis

106

1.81

1.59

1.1

3.59

8.09

u/ml

—

L04AX Other immunosuppressants

425

4758

0.89

1.59

1.1

5.07

5.45

u/ml

0.19

222

2514

Care involving dialysis

375

0.61

1.58

1.2

1.1

3.87

5.04

u/ml

0.17

200

Diagnoses used for exclusion with ILD

148

1216

1.22

1.58

1.1

3.63

5.08

u/ml

0.55

605

MS-disease / Multiple Sclerosis

671

0.71

1.57

1.0

1.1

5.47

5.46

u/ml

0.00

362

Adenocarcinoma, papilloma adenocarcinoma and mucinous carcinomas of rectum, excluding all cancers (controls excluding all cancers)

261

0.53

1.57

1.0

2.64

3.48

u/ml

—

118

Familial hypercholesterolemia

439

1.37

1.57

1.0

1.1

4.06

4.83

u/ml

0.18

224

Varicose veins

311

2684

0.87

1.56

1.1

3.32

3.23

u/ml

0.03

115

1191

Poisoning by drugs, medicaments and biological substances

212

2484

0.85

1.56

1.1

5.12

6.24

u/ml

0.49

107

1339

Other hammer toe(s) (acquired)

516

1.33

1.56

1.1

1.0

3.67

3.58

u/ml

0.01

210

Rheumatoid arthritis

162

1767

0.83

1.56

1.1

2.83

4.65

u/ml

1.40

790

Dental caries 1 and operation codes

890

4209

1.09

1.55

1.1

5.34

5.31

u/ml

0.02

476

2171

Injury of muscle and tendon at hip and thigh level

561

1.33

1.55

1.2

1.1

5.66

5.00

u/ml

0.18

286

Muscle strain

200

1.56

1.55

1.1

4.67

7.02

u/ml

0.40

109

Dermatitis herpetiformis

1.99

1.55

1.0

8.56

6.09

u/ml

—

DVT of lower extremities and pulmonary embolism

212

1799

1.18

1.54

1.0

1.1

3.34

4.25

u/ml

0.56

113

850

Malignant neoplasm of skin

187

1669

0.84

1.54

1.1

3.68

3.14

u/ml

0.21

742

Non-seminoma of testis, excluding all cancers (controls excluding all cancers)

0.00

1.54

0.0

1.1

—

8.82

—

Non-seminoma of testis

0.00

1.54

0.0

1.1

—

8.82

—

Glucagon-like peptide-1 (GLP-1) analogues

191

1857

0.84

1.53

1.0

1.1

3.26

3.50

u/ml

0.08

876

Umbilical hernia

195

1651

1.18

1.53

1.1

6.34

5.11

u/ml

0.37

110

837

Malignant neoplasm of prostate

585

0.75

1.53

1.0

1.1

5.50

2.97

u/ml

0.34

259

Single delivery by caesarean section

251

1681

0.86

1.53

1.1

5.98

5.84

u/ml

0.04

122

916

Nonorganic sleeping disorders

217

1855

1.17

1.53

1.1

6.00

6.21

u/ml

0.06

128

1009

Oxycodone

122

1452

0.81

1.53

1.0

1.1

2.90

4.12

u/ml

0.76

687

Extracorporeal dialysis

271

0.55

1.53

1.2

1.1

5.29

6.34

u/ml

—

147

Alopecia areata

201

1.56

1.52

1.0

1.1

12.77

5.26

u/ml

0.80

116

False labour

496

2804

1.11

1.52

1.1

5.71

5.39

u/ml

0.16

265

1459

Other and unspecified injuries of neck

2.20

1.52

1.1

5.37

6.70

u/ml

—

Ulcer of oesophagus

177

1.59

1.51

1.2

1.1

3.12

5.23

u/ml

0.53

Neuralgia and neuritis, unspecified

266

1.48

1.51

1.1

3.00

6.61

u/ml

1.17

129

Sleep disorders

237

2042

1.16

1.51

1.1

5.81

6.26

u/ml

0.15

136

1097

Alcohol abuse, main dg

1232

0.79

1.51

1.1

4.26

6.50

u/ml

0.74

655

Other or ill-defined heart diseases

258

1.48

1.50

1.2

1.1

8.66

6.95

u/ml

0.25

140

6-mercaptopurine

294

0.57

1.50

1.1

6.66

6.05

u/ml

—

167

Achalasia of cardia

2.09

1.50

1.0

2.37

5.57

u/ml

—

Hydronephrosis

537

0.69

1.49

1.0

1.1

2.24

5.29

u/ml

2.55

275

Other specified/unspecified dorsopathies

170

1.60

1.49

1.2

1.1

4.77

4.24

u/ml

0.06

Other and specified injuries of hip and thigh

1.96

1.49

1.1

0.85

9.81

u/ml

—

Dislocation, sprain and strain of joints and ligaments of thorax

186

1.57

1.49

1.0

1.1

9.51

6.76

u/ml

0.22

Other viral diseases

386

3431

1.13

1.49

1.1

7.48

6.42

u/ml

0.37

208

1972

Other specified disorders of muscle

139

1.67

1.49

1.0

1.1

2.50

5.71

u/ml

1.24

Vascular diseases of the intestine

2.01

1.48

1.1

1.0

6.91

u/ml

—

Polyp of the female genital tract

283

1432

1.15

1.48

1.1

3.22

4.74

u/ml

1.06

131

687

Congenital ichthyosis

2.60

1.48

1.1

1.0

3.59

11.37

u/ml

—

Other disorders starting during childhood or adolecense, excluding more controls

118

924

1.24

1.48

1.1

6.21

7.90

u/ml

0.51

623

Other functional intestinal disorders

371

3143

1.13

1.46

1.1

4.95

5.56

u/ml

0.20

195

1709

Malignant neoplasm of respiratory system and intrathoracic organs

394

0.65

1.46

1.0

9.25

3.24

u/ml

—

173

Other demyelinating diseases of the central nervous system

341

0.61

1.46

1.0

1.1

0.85

6.60

u/ml

—

180

Bullous disorders

195

1.55

1.46

1.0

1.1

7.29

4.97

u/ml

0.24

Contact with machinery

532

1.32

1.46

1.1

3.80

6.13

u/ml

0.60

268

Tongue abnormality

252

1.48

1.45

1.0

1.1

2.71

4.04

u/ml

0.52

120

Intermittent heterotropia

797

0.75

1.45

1.1

3.69

6.56

u/ml

1.11

510

Oral lichen ruber planus

1.89

1.45

1.0

1.1

8.02

2.78

u/ml

—

Rash and other nonspecific skin eruption

620

1.30

1.45

1.1

7.20

4.62

u/ml

0.56

334

Vitiligo

2.00

1.45

1.0

1.1

1.73

2.47

u/ml

—

Heterophoria

100

798

1.26

1.45

1.1

5.85

6.59

u/ml

0.17

471

Right bundle-branch block

1.88

1.45

1.0

1.1

3.31

8.20

u/ml

—

Dizziness and giddiness

607

4498

1.10

1.44

1.1

4.70

4.67

u/ml

0.01

302

2256

Benign neoplasm: Spinal meninges

2.76

1.44

1.0

—

4.93

—

Overexertion and strenuous or repetitive movements

736

1.27

1.44

1.1

4.72

5.67

u/ml

0.29

382

Ingrowing nail

396

1.37

1.43

1.1

5.70

6.20

u/ml

0.09

217

Mandibular retrognathia AND surgery (BSSRO)

221

1.51

1.42

1.1

4.39

5.23

u/ml

0.11

112

Crushed, pushed or stepped on by crowd or human stampede

103

827

1.25

1.42

1.1

9.29

7.14

u/ml

0.49

484

Presbyopia

337

1.40

1.42

1.1

3.44

4.33

u/ml

0.24

150

Other malignant neoplasms of skin (=non-melanoma skin cancer), excluding all cancers (controls excluding all cancers)

172

1397

0.84

1.42

1.1

3.61

2.77

u/ml

0.33

628

Hypersomnia

1.88

1.41

1.2

1.0

4.37

6.76

u/ml

—

Family history of malignant neoplasm

874

0.76

1.41

1.1

1.88

5.62

u/ml

3.62

434

Other and unspecified injuries of ankle and foot

406

1.37

1.41

1.1

5.36

6.10

u/ml

0.10

229

Achilles tendinitis

535

1.31

1.41

1.1

5.32

4.38

u/ml

0.16

241

Heart failure and coronary heart disease

484

0.72

1.41

1.0

0.95

3.95

u/ml

2.78

216

Impacted cerumen

457

1.34

1.41

1.1

3.88

5.95

u/ml

0.56

263

Amblyopia ex anopsia

441

1.35

1.40

1.1

4.47

6.97

u/ml

0.90

283

Adenocarcinoma and papilloma adenocarcinoma of rectum, excluding all cancers (controls excluding all cancers)

251

0.56

1.40

1.0

2.64

3.57

u/ml

—

115

Abnormal findings on diagnostic imaging of other body structures

588

1.30

1.40

1.1

3.50

4.29

u/ml

0.27

285

Acute nasopharyngitis (common cold)

113

912

1.24

1.40

1.1

6.39

5.79

u/ml

0.13

505

Poisoning by medicine

194

2264

0.85

1.40

1.1

5.36

6.12

u/ml

0.28

1231

Fitting and adjustment of other devices

146

1130

1.20

1.40

1.1

1.53

4.03

u/ml

4.20

525

Malignant neoplasm of breast, HER-negative

906

0.77

1.39

1.1

6.93

2.63

u/ml

0.64

411

Other specified and unspecified retinal disorders

111

1.72

1.39

1.1

1.0

1.56

5.51

u/ml

—

Bacterial infection, other or unspecified

253

2614

0.87

1.39

1.0

1.1

4.90

4.85

u/ml

0.02

138

1359

Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis

214

1.51

1.39

1.1

6.02

7.12

u/ml

0.15

111

Crohn disease (strict definition, all UC cases excluded)

450

1.34

1.39

1.1

9.06

6.46

u/ml

0.37

246

Use of pramipexole

111

900

1.24

1.39

1.1

5.91

3.81

u/ml

0.57

422

Cysts of oral region, not elsewhere classified

222

1.50

1.39

1.0

1.1

2.60

5.44

u/ml

1.43

119

Benign lipomatous neoplasm

190

1622

1.17

1.38

1.0

1.1

3.01

4.79

u/ml

2.13

792

Adenocarcinoma, papilloma adenocarcinoma and mucinous carcinomas of rectum

237

0.55

1.38

1.0

2.64

4.14

u/ml

—

Benign neoplasm: Vulva

1.82

1.38

1.1

10.78

1.87

u/ml

—

Benign neoplasm: Vulva

1.82

1.38

1.1

10.78

2.02

u/ml

—

Congenital malformations of great arteries

445

0.67

1.38

1.0

1.2

4.41

5.86

u/ml

0.43

337

Diseases of salivary glands

149

1246

1.20

1.38

1.1

4.46

5.20

u/ml

0.25

615

Ovarian hyperstimulation (induction)

207

1.52

1.38

1.0

1.1

1.72

4.97

u/ml

2.07

107

Polyarthritis, unspecified

182

1.55

1.38

1.1

6.97

4.82

u/ml

0.33

Abnormal involuntary movements

100

803

1.25

1.37

1.1

4.80

5.30

u/ml

0.15

419

Benign neoplasms

1097

5806

1.07

1.37

1.1

5.45

6.14

u/ml

0.70

580

3120

Dementia in Alzheimer disease

139

0.49

1.37

1.0

—

1.28

—

Delivery, wide proxy

319

1918

0.88

1.36

1.1

5.27

6.67

u/ml

0.80

172

1032

Gastric ulcer

468

1.33

1.36

1.1

1.92

3.86

u/ml

1.19

220

Other and unspecified mononeuropathies, also in other diseases

112

1.71

1.36

1.1

1.0

3.86

4.54

u/ml

—

Personality disorders, excluding more controls

309

2737

1.13

1.35

1.1

5.05

6.09

u/ml

0.60

178

1427

Aplastic and other anaemias

166

1856

0.85

1.35

1.1

5.45

4.64

u/ml

0.25

939

Benign neoplasm: Skin of eyelid, including canthus

653

1.27

1.35

1.0

1.1

3.07

4.34

u/ml

0.45

306

Viral meningitis

307

1.41

1.35

1.0

1.1

7.66

5.98

u/ml

0.26

165

Endometriosis of ovary

162

1365

1.19

1.35

1.0

1.1

4.28

5.06

u/ml

0.29

677

Pilonidal cyst

922

0.78

1.34

1.1

6.81

6.65

u/ml

0.02

494

Other disorders of conjunctiva

496

1.31

1.33

1.0

1.1

5.87

3.01

u/ml

0.73

217

Melanocytic naevi of other and unspecified parts of face

393

1.36

1.33

1.2

1.1

6.97

5.33

u/ml

0.29

204

Other benign neoplasms of skin

234

2037

1.15

1.33

1.1

3.78

5.11

u/ml

0.71

114

995

Lesion of ulnar nerve

798

1.24

1.32

1.1

2.38

5.15

u/ml

1.88

377

Other and unspecified visual disturbances

532

1.30

1.32

1.2

1.1

3.12

5.89

u/ml

1.92

277

Monoamine oxidase A inhibitors

620

1.28

1.32

1.0

1.1

5.98

4.59

u/ml

0.24

286

Other diseases of gallbladder

144

1.61

1.32

1.2

1.0

4.02

5.84

u/ml

0.30

Other and unspecified iridocyclitis

250

1.45

1.31

1.1

10.96

7.32

u/ml

0.37

134

Malignant neoplasm of bladder

1.81

1.31

1.1

1.0

3.09

4.44

u/ml

—

Cellulitis

185

1585

1.17

1.31

1.1

5.07

5.91

u/ml

0.34

856

All-cause Heart Failure

159

1354

0.85

1.31

1.0

1.1

4.97

3.18

u/ml

0.51

653

Myopia

162

1374

1.18

1.31

1.1

4.15

6.38

u/ml

1.17

757

Chalazion

773

1.25

1.30

1.1

4.70

5.62

u/ml

0.32

395

Delayed puberty

138

1.64

1.30

1.0

1.1

9.06

11.34

u/ml

0.21

101

Melanocytic naevi

278

2454

1.14

1.30

1.1

6.48

5.31

u/ml

0.52

153

1269

Oral leukoplakia, including avohilmo

1.77

1.29

1.1

0.24

6.77

u/ml

—

Misadventures to patients during surgical and medical care

774

1.24

1.29

1.1

4.42

4.89

u/ml

0.09

386

Myocarditis

318

1.39

1.29

1.0

1.1

8.19

5.33

u/ml

0.60

163

Other follicular disorders

579

1.29

1.1

6.29

5.83

u/ml

0.07

305

Episcleritis

344

1.37

1.29

1.1

3.99

4.69

u/ml

0.12

174

Sequelae of cerebrovascular disease

923

0.80

1.27

1.1

4.55

3.26

u/ml

0.31

425

Congenital malformations of cardiac septa

916

0.79

1.27

1.0

1.2

6.60

6.01

u/ml

0.12

616

Maternal care for other conditions predominantly related to pregnancy

295

2585

1.13

1.26

1.1

3.31

5.50

u/ml

3.06

145

1339

Retinal breaks without detachment

633

1.27

1.26

1.1

4.18

4.55

u/ml

0.08

292

Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure

457

4138

1.10

1.26

1.1

4.34

4.74

u/ml

0.20

236

2032

Oral lichen ruber planus, including avohilmo

252

1.44

1.26

1.0

1.1

4.43

3.99

u/ml

0.06

118

Juvenile arthritis (FINNGEN)

654

0.74

1.26

1.1

5.23

7.17

u/ml

0.32

392

Congenital malformations of the urinary system

574

0.73

1.26

1.0

1.1

5.69

6.45

u/ml

0.11

361

Other specified/unspecified systemic involvement of connective tissue

337

1.37

1.25

1.1

5.99

4.06

u/ml

0.31

163

Prepatellar bursitis

211

1.48

1.25

1.0

1.1

7.98

7.14

u/ml

—

Pacemaker

791

0.77

1.25

1.0

1.1

1.89

4.22

u/ml

2.13

389

Conotruncal defects

276

0.60

1.25

1.1

1.2

7.28

6.84

u/ml

0.05

206

Lymphoid leukaemia

241

0.58

1.24

1.2

4.47

7.71

u/ml

—

153

Abnormal results of function studies

529

1.29

1.24

1.0

1.1

6.29

5.80

u/ml

0.10

283

Oral leukoplakia and related diseases

187

1.50

1.24

1.0

1.1

1.28

4.93

u/ml

2.49

Colorectal adenocarcinoma, excluding all cancers (controls excluding all cancers)

481

0.71

1.24

1.0

1.1

1.53

3.05

u/ml

1.03

218

Other and unspecified erythematous conditions

147

1.58

1.23

1.1

1.42

5.84

u/ml

2.25

Chronic iridocyclitis

314

0.63

1.23

1.1

4.04

6.62

u/ml

—

175

Other/unspecified synovitis and tenosynovitis

707

1.25

1.23

1.0

1.1

3.91

5.54

u/ml

0.59

344

Other articular cartilage disorders

1.78

1.23

1.1

1.0

1.71

8.22

u/ml

—

Mandibular prognathia AND surgery (LeFortI or BSSO or LeFortI AND BSSO), including avohilmo

124

1.65

1.23

1.1

1.2

13.92

9.11

u/ml

0.39

Open wound of abdomen, lower back and pelvis

229

1.45

1.23

1.2

1.1

5.20

7.46

u/ml

0.35

131

Post-traumatic stress disorder

120

998

1.21

1.23

1.1

4.88

6.58

u/ml

0.50

556

Endometriosis of rectovaginal septum and vagina

486

1.30

1.22

1.1

2.63

5.05

u/ml

1.43

245

Emotional disorders and disorders of social functioning with onset specific to childhood

120

986

1.21

1.22

1.1

5.75

8.06

u/ml

0.89

638

Disorders of lipoprotein metabolism and other lipidaemias

479

3303

0.91

1.22

1.1

4.11

4.31

u/ml

0.09

227

1587

Amputation

240

0.58

1.22

1.0

14.98

5.25

u/ml

—

113

Pre-eclampsia

172

2000

0.86

1.22

1.1

2.75

4.76

u/ml

2.25

1008

Other neurotic disorders

204

1.48

1.22

1.3

1.1

1.81

6.14

u/ml

2.54

100

Viral hepatitis, IBD co-morbidity

479

0.71

1.22

1.2

1.1

3.78

7.82

u/ml

1.16

259

Disorders of vestibular function (Vertigo)

275

2420

1.13

1.22

1.1

4.11

4.30

u/ml

0.09

128

1145

Other specified/unspecified hearing loss

296

1.39

1.22

1.1

3.82

5.48

u/ml

0.46

156

Carcinoma in situ of breast, intraductal

361

0.66

1.21

1.0

11.79

2.17

u/ml

0.74

161

Laparoscopic right hemicolectomy

116

1.64

1.21

1.0

1.1

4.29

4.97

u/ml

—

Malignant neoplasm of bronchus and lung, excluding all cancers (controls excluding all cancers)

410

0.71

1.21

1.0

1.1

5.30

2.12

u/ml

0.43

188

Cardiac murmurs and other cardiac sounds

108

880

1.22

1.20

1.1

11.01

7.11

u/ml

0.98

514

Non-Hodgkin lymphoma, all, excluding all cancers (controls excluding all cancers)

443

0.70

1.20

1.0

1.1

8.20

4.50

u/ml

0.36

228

Combinations of oral blood glucose lowering drugs

1119

0.81

1.20

1.0

1.1

4.70

3.78

u/ml

0.18

529

Adenocarcinoma and papilloma adenocarcinoma of rectum

226

0.57

1.20

1.0

2.64

4.15

u/ml

—

Tic and related disorders

198

1.49

1.19

1.1

1.2

3.10

7.69

u/ml

2.10

144

Other rupture of muscle

2.34

1.19

1.0

3.56

5.69

u/ml

—

Colorectal cancer, excluding all cancers (controls excluding all cancers)

835

0.79

1.19

1.0

1.1

7.29

3.20

u/ml

0.70

372

Bulimia nervosa (incl. atypical)

463

1.31

1.19

1.2

1.1

2.92

6.77

u/ml

2.65

253

Benign neoplasm: Spinal meninges

2.33

1.19

1.0

1.1

—

5.44

—

Tic disorders

190

1.50

1.19

1.1

1.2

3.22

7.71

u/ml

1.86

140

Ischemic heart diseases

390

2701

0.90

1.19

1.0

1.1

3.51

3.68

u/ml

0.09

163

1272

Glomerular diseases

1084

0.81

1.19

1.1

5.64

5.77

u/ml

0.02

582

Other diseases of pleura

197

1514

1.15

1.19

1.1

4.77

4.07

u/ml

0.16

747

Female infertility, associated with anovulation

122

1020

1.20

1.19

1.0

1.1

6.06

5.42

u/ml

0.19

544

Cystic kidney disease

212

0.56

1.19

1.0

1.1

5.02

7.13

u/ml

—

127

Other disorders of Eustachian tube

157

1.54

1.18

1.1

11.87

7.19

u/ml

0.33

Alzheimer’s disease, wide definition, excluding more controls

171

0.60

1.18

1.0

2.11

1.71

u/ml

—

Superficial injury of hip and thigh

738

1.24

1.18

1.1

8.92

5.55

u/ml

0.63

384

Contact with and exposure to communicable diseases

416

4551

0.91

1.18

1.1

6.62

6.45

u/ml

0.07

229

2558

Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care

393

1.33

1.18

1.1

6.20

4.41

u/ml

0.24

198

Pure hypercholesterolaemia

369

2742

0.90

1.17

1.1

4.27

4.14

u/ml

0.05

185

1317

Other retinal disorders

293

2637

0.89

1.17

1.0

1.1

4.70

5.00

u/ml

0.12

150

1321

Sarcoidosis

730

1.24

1.17

1.1

4.05

4.06

u/ml

0.00

339

Female infertility, tubal origin

420

1.32

1.17

1.1

4.77

5.38

u/ml

0.12

209

Otorrhagia

0.00

1.17

0.0

1.1

—

7.67

—

Malignant neoplasm of eye and adnexa

0.00

1.17

0.0

1.1

—

6.12

—

Varicella [chickenpox]

429

1.31

1.17

1.1

4.55

6.83

u/ml

0.62

253

Other (seronegative) rheumatoid arthritis, wide

938

0.80

1.17

1.1

2.40

4.48

u/ml

1.48

455

Postpartum hemorraghe, parous women as controls

333

2621

1.12

1.16

1.1

5.47

4.88

u/ml

0.29

151

1296

Tooth agenesis EXCLUDE clefts and syndromes

598

1.27

1.16

1.1

9.64

8.24

u/ml

0.19

369

Fall on and from stairs and steps

191

1660

1.15

1.1

5.25

5.77

u/ml

0.16

106

861

Sequelae of injuries of lower limb

633

1.25

1.15

1.1

3.80

5.05

u/ml

0.47

318

Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified (FINNGEN)

460

3193

0.91

1.15

1.1

4.03

4.59

u/ml

0.37

218

1595

Secondary hypertension

514

0.73

1.14

1.0

1.1

5.19

5.83

u/ml

0.08

297

Delayed milestone in childhood

527

0.74

1.14

1.2

5.12

6.34

u/ml

0.23

411

Generalized epilepsy, mode (most common among epilepsy diagnosis)

335

1.36

1.14

1.1

7.18

6.45

u/ml

0.09

210

Unspecified kidney failure

235

0.59

1.14

1.1

1.0

11.44

6.54

u/ml

—

119

Seropositive rheumatoid arthritis, strict definition

790

0.78

1.14

1.0

1.1

3.85

4.57

u/ml

0.16

378

Urolithiasis

182

1578

1.16

1.14

1.1

4.81

5.21

u/ml

0.12

785

Rheumatoid arthritis, including avohilmo

189

2168

0.87

1.13

1.1

3.36

4.50

u/ml

0.68

104

1043

Other injuries of lower limb, level unspecified

2.03

1.13

1.0

1.1

5.43

9.18

u/ml

—

Nerve, nerve root and plexus disorders

984

5811

1.06

1.13

1.1

4.57

4.83

u/ml

0.21

468

2925

Septal defects

878

0.80

1.12

1.0

1.2

7.02

5.72

u/ml

0.27

599

Skin changes due to chronic exposure to nonionizing radiation

101

788

1.21

1.12

1.0

3.06

2.31

u/ml

0.24

344

Basal cell carcinoma, excluding all cancers (controls excluding all cancers)

161

1291

0.86

1.12

1.1

2.64

2.49

u/ml

0.07

569

Colorectal adenocarcinoma

471

0.72

1.12

1.0

1.1

1.53

3.10

u/ml

1.05

210

Pneumonia due to Streptococcus pneumoniae

192

1.47

1.11

1.0

1.1

14.84

6.93

u/ml

0.60

Melanocytic naevi of other and unspecified parts of face

406

1.31

1.11

1.2

1.1

6.97

5.06

u/ml

0.36

219

Disorder of lipoprotein metabolism, unspecified

388

1.32

1.11

1.0

1.1

1.69

4.06

u/ml

1.45

190

Clefts and syndromes for tooth agenesis exclusion, including avohilmo

490

0.73

1.11

1.1

1.2

1.71

6.49

u/ml

5.33

327

Symptoms and signs involving the nervous and musculoskeletal systems

483

4435

1.09

1.10

1.1

4.36

5.20

u/ml

0.74

261

2335

Juvenile osteochondrosis

346

1.34

1.10

1.0

1.1

10.36

6.71

u/ml

0.43

202

Other disorders of breast and lactation associated with childbirth

210

1.45

1.10

1.0

1.1

7.79

5.68

u/ml

0.21

110

Unspecified fall

420

3805

1.10

1.1

5.00

6.25

u/ml

0.97

251

2106

Insomnia

168

1454

1.16

1.10

1.1

5.92

6.22

u/ml

0.08

763

Other peripheral vertigo

363

1.33

1.09

1.1

4.04

4.03

u/ml

0.00

181

Erythema intertrigo

1.83

1.09

1.0

8.35

6.47

u/ml

—

Hordeolum and other deep inflammation of eyelid

425

1.30

1.09

1.1

1.50

5.63

u/ml

3.73

240

Retinal detachments and breaks

158

1361

1.16

1.09

1.1

8.35

3.68

u/ml

0.84

627

Benign neoplasm: Parotid gland

303

1.36

1.09

1.1

2.30

4.96

u/ml

1.36

146

Sacroiliitis, not elsewhere classified

443

1.29

1.08

1.0

1.1

8.95

6.47

u/ml

0.25

230

Phobic anxiety disorders

185

1615

1.15

1.07

1.1

6.60

7.30

u/ml

0.21

107

893

Focal epilepsy

139

1622

0.85

1.07

1.1

4.58

6.28

u/ml

0.86

914

Alcohol abuse, main dg, excluding more controls

1179

0.83

1.07

1.1

4.26

6.11

u/ml

0.57

621

Mixed specific developmental disorders

537

0.75

1.07

1.1

1.2

4.66

7.24

u/ml

0.50

403

Diseases of the digestive system

310

2787

1.11

1.07

1.1

5.11

5.42

u/ml

0.11

161

1491

Myocardial infarction, unclassifiable

365

0.71

1.06

1.0

1.1

3.66

4.00

u/ml

0.06

162

Other bullous disorders

121

1.58

1.06

1.0

7.59

5.33

u/ml

—

Dental caries 3 and operation codes

946

4565

1.06

1.1

5.52

5.47

u/ml

0.03

506

2369

Hypertensive diseases (excluding secondary)

592

3710

0.93

1.05

1.1

5.13

4.94

u/ml

0.10

290

1939

Stenosis and insufficiency of lacrimal passages

445

1.29

1.05

1.1

5.52

5.66

u/ml

0.02

240

Chondromalacia

162

1.49

1.04

1.1

1.0

4.07

4.88

u/ml

0.10

Bitten or struck by other mammals

123

1044

1.18

1.04

1.1

5.28

5.98

u/ml

0.22

556

Myocardial infarction

163

1349

0.87

1.04

1.0

2.51

2.70

u/ml

0.09

627

Thyrotoxicosis

189

1657

1.14

1.04

1.0

1.1

3.66

4.81

u/ml

0.70

100

830

Enlarged lymph nodes

133

1136

1.17

1.04

1.1

6.62

6.58

u/ml

0.01

603

Spermatocele

212

1.42

1.03

1.1

6.86

7.02

u/ml

0.02

100

Other arrhythmias

573

4067

1.08

1.03

1.1

5.42

4.69

u/ml

0.46

267

2052

Benign neoplasm: Tongue

1.64

1.03

1.0

12.15

6.35

u/ml

—

Benign neoplasm: Tongue

1.64

1.03

1.0

12.15

6.05

u/ml

—

Monoplegia

1.85

1.03

1.2

1.0

1.04

4.25

u/ml

—

Hypoparathyroidism

138

1.53

1.03

1.1

0.20

5.33

u/ml

—

Benign neoplasm: Other and unspecified parts of mouth

130

1.55

1.03

1.0

7.69

5.63

u/ml

0.20

Collagenous colitis

482

1.27

1.03

1.1

6.96

5.19

u/ml

0.30

251

Crohn's disease patients in KELA-register (KELA code 209, or 208 with ICD K50)

662

1.23

1.03

1.1

6.46

6.52

u/ml

0.01

368

Dental caries 1, only avohilmo

791

3788

1.07

1.02

1.1

5.40

5.42

u/ml

0.01

435

1941

Lichen sclerosus et atrophicus

447

1.28

1.02

1.1

4.28

4.35

u/ml

0.02

215

Dystonia

316

1.34

1.01

1.1

2.98

4.98

u/ml

0.74

165

Biological medication for rheuma

133

1548

0.86

1.01

1.1

3.08

6.28

u/ml

2.51

830

Other congenital malformations of ear

189

1.45

1.01

1.1

2.53

6.12

u/ml

1.65

127

Benign neoplasm of major salivary glands

377

1.30

1.01

1.1

2.01

4.32

u/ml

1.48

185

Symptoms and signs involving emotional state

248

1.38

1.00

1.1

11.29

5.77

u/ml

0.66

142

Non-follicular lymphoma, hilmo, excluding all cancers

298

0.67

1.00

1.0

1.1

12.36

5.01

u/ml

—

152

Carcinoma in situ of breast, intraductal

345

0.69

1.00

1.0

1.1

11.79

2.11

u/ml

0.75

149

Pre-eclampsia or eclampsia

184

2091

0.88

1.00

1.1

2.50

4.78

u/ml

3.12

1042

Spondylopathies

611

3450

1.08

1.00

1.1

3.84

4.80

u/ml

0.76

283

1679

Benign neoplasm: Larynx

1.62

1.00

1.2

1.1

3.63

5.86

u/ml

—

Diffuse brain injury

213

0.61

1.00

1.0

1.1

2.68

6.29

u/ml

—

121

L04AC Interleukin inhibitors

379

0.71

1.00

1.0

1.1

3.46

5.86

u/ml

0.73

198

Benign neoplasm of bone and articular cartilage

601

1.24

1.00

1.1

7.73

6.23

u/ml

0.27

318

Any mental disorder, or suicide (or attempt), or psychic disorders complicating pregnancy, partum or puerperium or nerve system disorders

295

3261

0.90

0.99

1.1

6.08

5.75

u/ml

0.11

142

1728

Algoneurodystrophy

240

1.39

0.99

1.1

5.62

5.59

u/ml

0.00

123

Female genital prolapse

221

1129

1.13

0.99

1.1

3.55

4.21

u/ml

0.30

101

522

Other abnormal immunological findings in serum

148

1.50

0.99

1.1

1.24

5.91

u/ml

2.43

Lower leg

0.00

0.98

0.0

1.1

—

6.94

—

Basal cell carcinoma, including avohilmo, excluding all cancers (controls excluding all cancers)

170

1338

0.87

0.98

1.1

2.56

2.52

u/ml

0.02

590

Contact with other hot fluids

275

1.36

0.98

1.1

3.86

7.10

u/ml

0.96

165

Caught, crushed, jammed or pinched in or between objects

406

1.29

0.98

1.1

8.07

6.30

u/ml

0.26

222

KRA_PSY_EATING, excluding more controls

136

1168

1.17

0.98

1.1

5.99

7.27

u/ml

0.34

683

Chronic myeloproliferative disease

0.00

0.98

0.0

1.1

—

4.56

—

Crohn disease (strict definition, require KELA)

621

1.23

0.98

1.1

7.01

6.57

u/ml

0.07

346

Malignant neoplasm of larynx

0.00

0.98

0.0

1.0

—

8.96

—

Ptosis of eyelid

344

1.31

0.98

1.1

1.39

3.33

u/ml

1.71

162

Other disorders of electrolyte and fluid balance, not elsewhere classified

0.00

0.98

0.0

1.1

—

5.09

—

Car occupant injured in other and unspecified transport accidents

205

1817

1.13

0.97

1.1

9.50

6.42

u/ml

0.64

102

968

Atrial fibrillation and flutter with reimbursement

119

896

0.85

0.97

1.0

1.1

3.05

3.07

u/ml

0.01

435

Nail disorders

585

1.24

0.97

1.1

4.47

5.56

u/ml

0.32

311

Lactose intolerance

241

1.38

0.97

1.1

5.88

6.18

u/ml

0.03

144

Anorexia (incl.atypical)

737

0.80

0.97

1.1

11.02

7.14

u/ml

0.60

422

Benign lipomatous neoplasm of skin and subcutaneous tissue of other and unspecified sites

0.00

0.97

0.0

1.0

—

4.88

—

Alzheimer’s disease, wide definition

228

0.66

0.97

1.0

1.81

1.20

u/ml

—

Disorders of lens

336

2330

0.91

0.97

1.1

4.82

3.66

u/ml

0.32

159

1071

Open wound of hip and thigh

250

1.37

0.96

1.1

5.93

7.03

u/ml

0.14

146

Benign neoplasm: salivary glands, exclude unknown (D119)

345

1.31

0.96

1.1

2.19

4.62

u/ml

1.37

170

Sequelae of injuries of upper limb

640

1.22

0.96

1.1

2.60

5.05

u/ml

1.26

328

Varicose veins of other sites

354

1.30

0.96

1.1

3.43

6.18

u/ml

0.98

177

Other disorders of cornea

478

1.26

0.96

1.1

8.92

5.21

u/ml

0.57

236

613

0.78

0.96

1.1

1.2

5.52

6.00

u/ml

0.10

446

Intestinal malabsorption

276

1.35

0.96

1.1

3.50

5.98

u/ml

0.56

154

Other juvenile arthritis

557

0.77

0.95

1.1

5.25

7.20

u/ml

0.27

339

Hyperhidrosis

242

1.37

0.95

1.2

1.1

3.11

6.66

u/ml

1.23

130

Benign neoplasm: Conjunctiva

141

1.50

0.95

1.0

1.1

0.88

6.03

u/ml

2.45

Speech and linguistic disorders

168

1415

1.15

0.95

1.1

6.29

7.77

u/ml

0.47

109

926

Sequelae of injuries, of poisoning and of other consequences of external causes

196

1736

1.13

0.95

1.1

2.84

5.73

u/ml

3.74

108

900

Glomerular disorders in diseases classified elsewhere

591

0.78

0.94

1.0

1.1

9.29

5.09

u/ml

0.58

309

Other congenital malformations of skin

382

1.29

0.94

1.1

3.89

5.57

u/ml

0.36

235

Crohn's disease of large intestine

444

1.27

0.94

1.1

6.91

6.14

u/ml

0.12

242

Actinic keratosis

729

1.20

0.94

1.0

3.18

2.29

u/ml

0.27

316

Ischaemic heart disease, wide definition

379

2589

0.92

0.94

1.1

3.53

3.46

u/ml

0.03

158

1218

Hypoplasia of dental enamel, prenatal , including avohilmo

154

0.56

0.94

1.1

1.3

2.30

5.78

u/ml

—

122

Exposure to other and unspecified animate mechanical forces

286

1.34

0.94

1.1

3.57

6.50

u/ml

0.82

167

Astigmatism

660

1.22

0.94

1.1

4.20

6.45

u/ml

1.00

416

Foreign body in alimentary tract

338

1.31

0.94

1.1

5.61

6.57

u/ml

0.19

203

Other disorders of veins

271

2445

1.11

0.94

1.1

4.25

3.77

u/ml

0.19

140

1122

5-aminosalicylic acid

196

1738

1.13

0.93

1.1

7.69

6.24

u/ml

0.48

900

Whooping cough

1.85

0.93

1.2

1.1

0.14

8.27

u/ml

—

Use of hypnotics and sedatives

947

5785

0.95

0.93

1.1

4.15

4.85

u/ml

0.72

459

2942

Lymphoid leukaemia

221

0.63

0.93

1.2

4.47

7.59

u/ml

—

146

Supernumerary teeth EXCLUDE clefts and syndromes, including avohilmo

126

1.54

0.93

1.1

1.2

11.03

7.60

u/ml

0.29

Tumor necrosis factor alpha inhibitors

123

1428

0.86

0.93

1.1

2.71

6.15

u/ml

2.69

775

COPD, hospital admissions 3, with asthma pneumonia sepsis

522

1.22

0.93

1.1

3.35

4.99

u/ml

0.36

242

Focal epilepsy, mode (most common among epilepsy diagnosis)

117

1363

0.86

0.92

1.1

3.85

6.30

u/ml

1.58

766

Acute gastritis

295

1.33

0.92

1.1

1.50

4.87

u/ml

1.80

142

Cardiac arrest

211

0.65

0.92

1.0

1.1

5.09

4.17

u/ml

—

100

Convergent concomitant strabismus

643

0.79

0.92

1.0

1.1

5.88

6.47

u/ml

0.12

372

Superficial injury of ankle and foot

151

1319

1.15

0.92

1.1

10.44

6.59

u/ml

1.01

748

Malignant neoplasm of bronchus and lung

317

0.71

0.92

1.0

0.79

2.62

u/ml

—

135

Cerebral palsy

219

0.63

0.91

1.1

1.2

11.32

6.05

u/ml

—

147

Polycystic ovarian syndrome, consortium definition

832

4734

1.06

0.91

1.1

4.45

5.24

u/ml

0.87

413

2364

Postprocedural disorders of nervous system

764

0.81

0.91

1.0

1.1

6.05

6.54

u/ml

0.10

423

Non-follicular lymphoma

291

0.69

0.91

1.0

1.1

12.36

4.95

u/ml

—

145

Other congenital malformations of tongue, mouth and pharynx

305

1.33

0.90

1.2

4.51

7.19

u/ml

1.09

230

Benign neoplasm: Larynx

102

1.58

0.90

1.2

1.1

3.63

5.69

u/ml

—

Tic and related disorders

211

1.40

0.90

1.1

1.2

3.10

6.86

u/ml

1.57

158

Background retinopathy and retinal vascular changes

1.76

0.90

1.0

1.1

10.17

4.31

u/ml

—

Papulosquamous disorders

278

2521

1.10

0.90

1.1

4.25

5.00

u/ml

0.36

141

1256

Other congenital malformations

125

1079

1.16

0.89

1.1

4.21

6.17

u/ml

0.88

658

Premature rupture of membranes

280

2267

0.91

0.89

1.1

5.12

5.47

u/ml

0.17

130

1204

Habitual aborter

237

1.36

0.89

1.1

6.75

5.77

u/ml

0.08

126

Gout, idiopatic and unspecified

630

0.79

0.89

1.1

1.82

4.23

u/ml

2.11

288

Diseases of inner ear

326

2918

1.09

0.88

1.1

4.57

4.35

u/ml

0.09

156

1394

Crohn disease (strict definition, require KELA, min 2 HDR)

611

1.22

0.88

1.1

6.74

6.64

u/ml

0.01

339

Lung cancer and mesothelioma

231

1.33

0.88

1.0

4.94

2.86

u/ml

0.27

Endometriosis ASRM stages 1,2

195

1737

1.13

0.88

1.1

4.19

5.22

u/ml

0.50

876

Erythema nodosum

152

1.46

0.88

1.1

4.64

3.94

u/ml

0.14

Other heart diseases

560

3960

0.93

0.88

1.1

6.14

5.46

u/ml

0.41

286

2147

Other congenital malformations of the digestive system

581

1.22

0.88

1.2

3.95

6.50

u/ml

1.49

394

Secondary and unspecified malignant neoplasm of lymph nodes

312

0.70

0.88

1.1

4.80

4.78

u/ml

0.00

156

Other/unspecified seropositive rheumatoid arthritis (ICD-10)

113

1314

0.86

0.88

1.0

1.1

2.85

4.59

u/ml

0.90

617

Other specified transport accidents

2.03

0.87

1.0

1.1

6.76

13.22

u/ml

—

Other/unspecified seropositive rheumatoid arthritis

114

1324

0.86

0.87

1.0

1.1

2.85

4.58

u/ml

0.89

619

Symptoms and signs concerning food and fluid intake

702

1.20

0.87

1.1

2.31

6.15

u/ml

3.77

427

Alcohol-induced chronic pancreatitis

276

0.69

0.87

1.0

1.1

0.89

5.92

u/ml

—

126

Benign neoplasm: Other and unspecified parts of mouth

136

1.48

0.87

1.0

7.69

4.91

u/ml

0.28

Disorders in reading

230

1.37

0.86

1.1

5.99

7.82

u/ml

0.21

156

Benign lipomatous neoplasm

190

1692

1.12

0.86

1.0

1.1

3.01

4.48

u/ml

1.66

822

Other specified/unspecified disorders of bone/cartilage

128

1.49

0.86

1.1

1.0

6.92

6.63

u/ml

—

Congenital malformations of heart and great arteries

129

1434

0.87

0.86

1.0

1.1

5.70

6.28

u/ml

0.17

900

150

1318

1.14

0.86

1.1

3.26

5.46

u/ml

1.99

109

685

Benign lipomatous neoplasm of other sites/unspecified

299

1.31

0.85

1.1

3.17

3.80

u/ml

0.19

140

Coxarthrosis, primary

234

1829

1.11

0.85

1.1

1.0

2.93

3.02

u/ml

0.03

101

806

Pedestrian injured in collision with pedal cycle

170

1.42

0.85

1.1

3.27

6.50

u/ml

0.86

Hypopituitarism

680

0.80

0.85

1.1

1.2

6.28

6.42

u/ml

0.02

425

Benign neoplasm: Long bones of lower limb

230

1.36

0.85

1.0

1.1

3.92

7.08

u/ml

0.78

132

Benign neoplasm: Long bones of lower limb

230

1.36

0.85

1.0

1.1

3.92

7.18

u/ml

0.81

129

Dental caries 1

773

3726

1.06

0.85

1.1

5.53

5.37

u/ml

0.09

423

1905

Loose body in joint

104

1.55

0.85

1.2

1.1

8.75

8.89

u/ml

—

Autoimmune diseases related-to ILD

839

6991

1.06

0.85

1.1

5.34

5.51

u/ml

0.10

396

3633

Other and unspecified nail disorders

1.60

0.85

1.1

1.79

7.56

u/ml

—

Undescended testicle

248

0.67

0.84

1.1

1.2

5.30

7.63

u/ml

—

193

Small fibre neuropathy

1.60

0.84

1.2

1.0

1.78

5.27

u/ml

—

Diabetic nephropathy

507

0.78

0.84

1.0

1.1

7.88

5.07

u/ml

0.46

229

Other and unspecified coagulation defects

380

1.27

0.84

1.2

1.1

5.73

5.29

u/ml

0.07

204

Focal epilepsy, strict definition

125

1436

0.87

0.84

1.1

4.03

6.40

u/ml

1.45

811

Other and unspecified myopathies

309

0.71

0.84

1.0

1.1

2.33

5.79

u/ml

1.77

155

Stomatitis and related lesions

615

1.21

0.83

1.1

11.21

6.12

u/ml

0.84

332

Benign neoplasm: Parotid gland

318

1.29

0.83

1.1

2.30

4.98

u/ml

1.44

158

Dental caries, including avohilmo

772

3725

1.06

0.83

1.1

5.54

5.37

u/ml

0.10

422

1905

Postpartum haemorrhage due to anatomy

144

1265

1.14

0.83

1.1

6.71

5.65

u/ml

0.36

663

Lesion of plantar nerve

257

1.33

0.83

1.1

1.0

2.82

3.54

u/ml

0.21

115

Mumps

146

1.45

0.83

1.1

1.0

0.82

6.67

u/ml

—

Gout

709

0.82

0.83

1.1

1.0

2.75

4.51

u/ml

0.76

321

Calcific aortic valvular stenosis, diagnosis (helper)

575

1.21

0.83

1.0

1.1

1.54

4.24

u/ml

2.10

270

Operations 2 for CAVS

575

1.21

0.83

1.0

1.1

1.54

4.24

u/ml

2.10

270

Benign neoplasm: Conjunctiva

146

1.45

0.83

1.0

0.88

5.62

u/ml

2.52

Cluster headache, strict, including avohilmo

399

1.26

0.82

1.1

5.89

6.31

u/ml

0.06

207

Ulcerative colitis

189

2112

0.89

0.82

1.1

6.14

6.49

u/ml

0.10

1141

Congenital malformations of breast

189

1.39

0.82

1.2

1.1

2.42

5.90

u/ml

1.09

100

Single delivery by forceps and vacuum extractor

224

1512

0.90

0.82

1.1

4.87

6.08

u/ml

0.67

107

838

Retinal detachment with retinal break

435

1.24

0.82

1.1

16.18

3.44

u/ml

0.81

202

Malignant neoplasm of rectum

237

0.67

0.81

1.1

1.0

6.87

4.06

u/ml

—

105

Abnormalities of forces of labour

118

1024

1.16

0.81

1.1

4.81

4.63

u/ml

0.05

493

Postmenopausal bleeding

138

661

1.15

0.81

1.1

1.90

2.86

u/ml

0.50

273

Fracture of neck

201

0.64

0.81

1.2

1.1

0.60

6.11

u/ml

—

103

Recurring oral aphthae

320

1.29

0.81

1.1

6.80

5.55

u/ml

0.16

187

Long labour

320

2567

1.09

0.80

1.1

4.02

5.06

u/ml

0.79

162

1305

Supplementary factors related to causes of morbidity and mortality classified elsewhere

279

2549

1.10

0.80

1.1

6.11

6.13

u/ml

0.00

155

1388

Cirrhosis, broad definition used in the article https://doi.org/10.1101/594523

532

0.79

0.80

1.0

1.1

1.38

4.36

u/ml

2.87

265

Other appendicitis

545

1.21

0.80

1.0

1.1

3.87

4.89

u/ml

0.25

264

Wide developmental disorders

596

0.80

1.1

1.2

3.70

7.28

u/ml

1.07

406

Other female pelvic inflammatory diseases

127

1109

1.15

0.80

1.1

3.14

4.76

u/ml

1.07

524

692

0.82

0.80

1.1

1.2

5.12

6.86

u/ml

0.53

503

Marasmic kwashiorkor

0.00

0.80

0.0

1.1

—

4.59

—

Cluster headache, wide,, including avohilmo

410

1.25

0.80

1.1

5.89

6.23

u/ml

0.05

212

Malignant melanoma, excluding all cancers (controls excluding all cancers)

587

0.80

1.1

2.65

3.16

u/ml

0.19

268

Pedestrian injured in collision with two- or three-wheeled motor vehicle

0.00

0.80

0.0

1.1

—

5.09

—

Unspecified protein-energy malnutrition

0.00

0.80

0.0

1.1

—

4.17

—

Other congenital malformations of circulatory system

139

1.45

0.79

1.2

1.0

9.67

5.32

u/ml

0.48

Rheumatic fever with heart involvement

0.00

0.79

0.0

1.0

—

14.18

—

Diseases of peritoneum

446

1.24

0.79

1.1

2.67

4.44

u/ml

0.56

226

Persons encountering health services for specific procedures, not carried out

546

1.21

0.79

1.1

5.88

5.45

u/ml

0.07

282

Peripheral artery operations in Hilmo

282

0.71

0.79

1.1

1.0

10.66

5.25

u/ml

0.38

127

Secondary malignant neoplasm of other and unspecified sites

0.00

0.79

0.0

1.1

—

2.16

—

Benign neoplasm: Caecum

268

1.31

0.79

1.0

3.31

3.40

u/ml

0.01

115

Vascular dementia (undefined)

0.00

0.79

0.0

1.0

—

5.06

—

Malignant melanoma of skin, excluding all cancers (controls excluding all cancers)

486

0.78

0.79

1.1

3.03

2.96

u/ml

0.02

224

Calcific aortic valvular stenosis, including rheumatic fever

578

1.20

0.79

1.0

1.1

1.54

4.21

u/ml

2.07

272

Follicular adenocarcinoma of thyroid gland

0.00

0.79

0.0

1.0

—

10.70

—

Other keratitis

841

1.17

0.78

1.1

6.30

6.02

u/ml

0.05

442

Circumscribed brain atrophy

0.00

0.78

0.0

1.1

—

4.17

—

Mixed connective tissue disease

375

1.26

0.78

1.1

3.93

3.98

u/ml

0.01

177

Gout, FINNGEN

772

0.83

0.78

1.1

2.75

4.03

u/ml

0.52

361

Malignant melanoma of skin

373

0.75

0.78

1.1

2.96

3.01

u/ml

0.01

175

Medial epicondylitis

199

1.36

0.78

1.3

1.0

9.02

5.40

u/ml

0.44

Macular hole

1.56

0.78

1.0

1.1

1.24

1.63

u/ml

—

Left bundle-branch block

199

1.36

0.78

1.0

2.25

3.66

u/ml

0.48

Benign lipomatous neoplasm of skin and subcutaneous tissue of other and unspecified sites

0.00

0.78

0.0

1.0

—

4.92

—

Other epidermal thickening

208

1.35

0.77

1.1

5.65

6.23

u/ml

0.07

108

Optic neuritis

360

0.75

0.77

1.0

1.1

5.85

6.30

u/ml

0.06

190

Abrasion of teeth

245

1637

1.10

0.77

1.1

2.96

5.08

u/ml

3.21

140

811

Qualitative platelet defects

2.22

0.77

1.2

8.58

4.70

u/ml

—

Acute pancreatitis (for exclusion)

954

0.85

0.77

1.1

5.50

4.79

u/ml

0.13

461

Vitreous haemorrhage

394

0.76

1.0

1.1

19.90

4.45

u/ml

0.54

200

Adult respiratory distress syndrome

0.00

0.76

0.0

1.1

—

5.87

—

Anomalies of pupillary function

149

1.42

0.76

1.1

6.74

7.89

u/ml

—

Viral conjunctivitis

149

1.42

0.76

1.0

1.1

6.85

5.74

u/ml

0.10

Other vitreous opacities

132

1.45

0.76

1.1

1.16

4.86

u/ml

—

Venous thromboembolism

293

2612

1.09

0.76

1.1

3.33

4.36

u/ml

0.88

156

1236

Viral Sepsis

123

1077

1.14

0.76

1.1

5.34

5.29

u/ml

0.01

587

Seropositive rheumatoid arthritis, wide

117

1338

0.87

0.76

1.0

1.1

2.77

4.55

u/ml

0.97

625

Prolonged pregnancy

200

2019

0.90

0.75

1.1

6.75

5.73

u/ml

0.41

107

1084

Acute pancreatitis

952

0.85

0.75

1.1

5.50

4.73

u/ml

0.14

461

Benign neoplasm of major salivary glands

395

1.24

0.75

1.1

2.01

4.75

u/ml

1.88

195

Sudden idiopathic hearing loss

395

1.24

0.75

1.1

1.0

6.08

4.39

u/ml

0.21

192

Atrophic disorders of skin

100

863

1.16

0.75

1.1

5.92

4.56

u/ml

0.33

431

Seropositive rheumatoid arthritis

117

1334

0.87

0.75

1.0

1.1

2.77

4.43

u/ml

0.88

616

Deficiency of other B group vitamins

1.65

0.75

1.2

1.0

1.17

4.07

u/ml

—

Benign neoplasm: Rectum

540

1.21

0.75

1.0

1.1

2.21

4.65

u/ml

1.03

251

Other symptoms and signs involving the nervous and musculoskeletal systems

359

3327

1.08

0.75

1.1

3.82

5.27

u/ml

1.73

191

1754

Chronic mastoiditis

1.57

0.75

1.0

1.1

1.88

7.25

u/ml

—

Scabies

342

1.26

0.75

1.1

1.34

7.16

u/ml

5.99

181

Crohn's disease of small intestine

615

1.19

0.74

1.1

7.27

6.38

u/ml

0.14

331

Benign neoplasm: Caecum

271

1.29

0.74

1.0

3.31

3.22

u/ml

0.01

124

Unstable angina pectoris

869

0.86

0.74

1.1

1.0

2.08

3.24

u/ml

0.51

382

Contusion of toe(s) without damage to nail

219

1.33

0.74

1.1

6.89

5.14

u/ml

0.17

118

Congenital deformities of hip

272

1.30

0.74

1.2

1.80

7.43

u/ml

3.19

180

Disorders of lacrimal system and orbit in diseases classified elsewhere

133

1.44

0.74

1.0

1.1

2.26

3.08

u/ml

0.32

Corneal ulcer

157

1400

1.12

0.74

1.1

6.78

5.87

u/ml

0.23

720

Meralgia paraesthetica

167

1.38

0.74

1.1

1.0

1.42

4.81

u/ml

—

Gout, unspecified

492

0.79

0.73

1.1

1.34

4.67

u/ml

3.15

222

Trigger finger

772

1.17

0.73

1.0

1.1

4.50

4.84

u/ml

0.07

351

malignant neoplasm of female genital organs

525

0.80

0.73

1.0

1.1

4.69

2.02

u/ml

0.55

241

Other and unspecified injuries of lower leg

616

1.19

0.73

1.0

1.1

7.17

6.58

u/ml

0.08

337

Calcific aortic valvular stenosis

584

1.19

0.73

1.0

1.1

1.54

4.20

u/ml

2.08

276

Calcific aortic valvular stenosis, operated

584

1.19

0.73

1.0

1.1

1.54

4.20

u/ml

2.08

276

Cardiomyopathy (excluding other)

480

0.79

0.73

1.1

7.51

5.08

u/ml

0.32

245

Injuries to the abdomen, lower back, lumbar spine and pelvis

296

2709

1.09

0.72

1.1

6.76

5.98

u/ml

0.29

179

1438

Barrett oesophagus

142

1.41

0.72

1.1

1.0

0.22

4.94

u/ml

—

Congenital deformities of feet

264

1.30

0.72

1.0

1.1

8.61

6.87

u/ml

0.21

164

Benign neoplasm of bone and articular cartilage

626

1.19

0.72

1.1

7.73

6.08

u/ml

0.31

332

Emotional disorders starting during childhood or adolescence

109

945

1.15

0.72

1.1

6.24

7.88

u/ml

0.51

608

Fall on and from ladder

299

1.27

0.72

1.1

6.11

6.43

u/ml

0.04

155

Other and unspecified injuries of thorax

1.59

0.72

1.0

1.1

9.46

10.23

u/ml

—

Other bacterial intestinal infections

106

923

1.15

0.72

1.1

2.55

5.16

u/ml

2.33

473

Burn and corrosion of trunk

194

1.35

0.71

1.1

6.84

7.54

u/ml

0.07

113

Cardiac arrhythmias

685

4775

0.95

0.71

1.1

5.51

5.16

u/ml

0.22

337

2513

Abnormal blood-pressure reading, without diagnosis

220

1.32

0.71

1.1

0.53

8.02

u/ml

5.49

116

Ménière disease

353

1.25

0.71

1.0

1.1

4.95

3.42

u/ml

0.33

166

Benign neoplasm of other and unspecified sites

134

1.42

0.71

1.1

1.0

4.81

6.87

u/ml

—

Diseases of arteries, arterioles and capillaries (FINNGEN)

125

991

0.88

0.71

1.0

1.1

4.49

3.47

u/ml

0.28

499

Maxillary retrognathism

221

1.33

0.71

1.1

2.48

8.02

u/ml

2.61

146

Impotence

170

0.65

0.70

1.1

7.71

7.04

u/ml

—

Familial hypercholesterolemia, with ischemic heart disease

177

1.36

0.70

1.0

2.15

4.30

u/ml

—

Lesion of radial nerve

160

1.38

0.70

1.1

1.0

1.15

4.41

u/ml

2.06

Contusion of other and unspecified parts of foot

518

1.20

0.70

1.1

14.79

7.18

u/ml

0.96

288

Dental caries 3

849

4133

1.05

0.70

1.1

5.21

5.53

u/ml

0.20

463

2132

Implicit viral Sepsis

122

1075

1.14

0.70

1.1

4.67

5.30

u/ml

0.21

586

Right ventricular outflow tract obstruction

180

0.65

0.70

1.1

1.2

10.29

6.93

u/ml

—

141

Gonarthrosis [arthrosis of knee](FG)

497

3114

0.94

0.70

1.1

2.93

3.59

u/ml

0.72

240

1407

Excessive vomiting in pregnancy

842

1.16

0.70

1.1

5.05

5.97

u/ml

0.23

441

Early lumbar disc prolapse operation

133

1180

1.13

0.70

1.1

4.46

6.15

u/ml

0.81

613

Disorders of tooth development and eruption

775

1.16

0.69

1.1

3.07

6.67

u/ml

2.58

504

Social disorders starting during childhood or adolecense, excluding more controls

127

1.44

0.69

1.0

1.1

1.09

8.86

u/ml

4.51

Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium

239

0.71

0.69

1.0

1.1

0.95

4.23

u/ml

—

129

Nontoxic diffuse goitre

118

1.45

0.69

1.1

11.26

2.37

u/ml

—

Congenital malformations of the nervous system

296

0.74

0.69

1.1

1.2

6.81

5.98

u/ml

0.09

198

Benign neoplasm of other and unspecified sites

135

1.41

0.69

1.1

1.0

4.81

7.04

u/ml

—

Migraine with aura, drug-induced

1.66

0.69

1.2

1.1

3.00

4.01

u/ml

—

Macular pucker

301

1.26

0.69

1.0

1.1

0.88

2.64

u/ml

1.96

137

Thyrotoxicosis, other and/or unspecified

154

1379

1.12

0.69

1.1

3.98

4.96

u/ml

0.46

700

Toxic effect of carbon monoxide

1.57

0.69

1.0

2.28

10.37

u/ml

—

Influenza and pneumonia

1160

7326

1.04

0.68

1.1

6.06

5.59

u/ml

0.35

680

3821

Benzodiazepine use

899

6690

0.96

0.68

1.1

4.32

5.20

u/ml

1.03

451

3393

Contact with other sharp object(s)

628

0.82

0.68

1.0

1.1

5.87

6.98

u/ml

0.29

334

Other noninflammatory disorders of uterus, except cervix

117

701

1.14

0.68

1.1

1.50

3.66

u/ml

2.83

313

Other and unspecified injuries of head

408

0.78

0.68

1.1

5.83

5.62

u/ml

0.02

227

Parkinson's disease

296

0.74

0.68

1.0

1.22

2.87

u/ml

—

126

Mixed disorders of conduct and emotions

429

0.79

0.68

1.0

1.1

5.48

7.74

u/ml

0.43

272

Congenital malformations of eye, ear, face and neck

826

1.16

0.68

1.1

4.82

6.53

u/ml

0.54

501

Dental caries 3, only avohilmo

858

4185

1.05

0.68

1.1

5.03

5.57

u/ml

0.41

467

2165

Benign lipomatous neoplasm of other sites/unspecified

311

1.26

0.67

1.1

3.17

3.66

u/ml

0.14

160

Dislocation, sprain and strain of joints and ligaments of head

420

1.22

0.67

1.1

4.92

5.79

u/ml

0.15

234

Injuries to the thorax

290

2681

1.08

0.67

1.1

6.26

5.58

u/ml

0.25

149

1391

Ankyloglossia

366

1.24

0.67

1.2

4.16

7.37

u/ml

1.48

272

Failed attempted abortion

145

1.40

0.67

1.1

1.52

5.19

u/ml

—

Use of teriflunomide

1.53

0.67

1.0

6.66

3.68

u/ml

—

Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck

267

1.28

0.67

1.1

2.41

4.39

u/ml

0.78

122

Overjet

465

1.21

0.66

1.2

1.1

8.80

7.77

u/ml

0.18

320

Open wound of lower leg

113

996

1.14

0.66

1.0

1.1

7.04

6.70

u/ml

0.07

544

Malignant neoplasm of colon, excluding all cancers (controls excluding all cancers)

517

0.81

0.66

1.0

1.1

6.33

3.72

u/ml

0.25

242

Maternal care for known or suspected disproportion

476

1.20

0.66

1.0

1.1

3.48

4.77

u/ml

0.29

236

Enterocolitis due to Clostridium difficile

373

0.78

0.66

1.1

4.78

4.23

u/ml

0.12

185

conjunctival haemorrhage

232

1.30

0.66

1.0

1.1

9.00

3.22

u/ml

0.74

103

Graves ophthalmopathy

128

1.41

0.66

1.0

2.26

3.04

u/ml

0.30

Malignant neoplasm of urinary organs, excluding all cancers (controls excluding all cancers)

328

0.76

0.66

1.0

1.1

6.60

3.77

u/ml

—

160

Other abnormal uterine and vaginal bleeding

165

1059

1.11

0.66

1.1

3.50

4.95

u/ml

0.73

519

Personal history of malignant neoplasm

225

0.71

0.65

1.1

21.57

5.46

u/ml

—

128

Cluster headache, wide

268

1.27

0.65

1.1

5.65

7.62

u/ml

0.28

131

Bacterial intestinal infections, IBD co-morbidities

105

922

1.14

0.65

1.1

2.41

5.44

u/ml

2.86

464

Other congenital malformations, not elsewhere classified

129

1.42

0.65

1.1

1.2

5.32

5.38

u/ml

—

Other and unspecified epidermal thickening

137

1.39

0.65

1.2

1.1

3.43

6.66

u/ml

0.55

Pedestrian injured in transport accident

431

1.21

0.65

1.1

4.46

5.95

u/ml

0.30

226

Gonarthrosis,primary

482

3218

0.94

0.65

1.1

2.77

3.18

u/ml

0.37

224

1417

Congenital malformations of aortic and mitral valves

360

0.77

0.65

1.0

1.2

2.39

7.68

u/ml

2.81

233

Keratoconus

163

1.36

0.64

1.1

12.90

7.63

u/ml

0.39

Myocardial infarction, without ST-elevation

112

911

1.13

0.64

1.1

1.0

2.91

2.89

u/ml

0.01

404

Diabetic retinopathy, excluding more controls

104

668

0.88

0.64

1.0

7.33

3.92

u/ml

0.84

307

Cluster headache, strict

260

1.28

0.64

1.1

5.65

7.77

u/ml

0.30

128

Other and unspecified acne

129

1.41

0.64

1.2

1.1

1.93

6.49

u/ml

2.07

Xanthelasma of eyelid

1.74

0.64

1.0

1.1

—

5.21

—

Heart failure and antihypertensive medication

113

845

0.88

0.64

1.0

1.1

6.25

3.82

u/ml

0.53

420

severe traumatic brain injury, does not include concussion

839

0.86

0.64

1.0

1.1

4.28

5.15

u/ml

0.30

422

Ventral hernia

129

1150

1.12

0.63

1.0

1.1

3.94

4.45

u/ml

0.16

562

Bursitis of shoulder

112

1.44

0.63

1.1

1.0

1.70

8.32

u/ml

—

Gout, strict definition

393

0.79

0.63

1.1

2.39

4.18

u/ml

0.86

172

Degenerative macular diseases

269

1.27

0.63

1.0

2.90

3.88

u/ml

0.21

124

Fracture of shoulder and upper arm

227

2468

0.92

0.63

1.1

5.04

6.51

u/ml

0.65

120

1346

Pathological resorption of teeth

181

1.33

0.63

1.0

1.1

2.16

5.99

u/ml

2.17

101

Melanoma in situ

1.50

0.63

1.2

1.0

3.29

2.63

u/ml

—

Other and unspecified mood [affective] disorders

794

1.15

0.63

1.0

1.1

4.82

7.18

u/ml

0.72

435

Ulcerative ileocolitis

314

0.76

0.63

1.1

9.09

5.35

u/ml

0.39

163

Contact with heat and hot substances

451

1.20

0.63

1.1

5.10

6.67

u/ml

0.41

263

Chronic periodontitis, complicated

370

0.78

0.63

1.0

1.1

0.88

3.68

u/ml

3.43

174

Unspecified misadventure during surgical and medical care

234

1.29

0.63

1.0

1.1

1.14

4.83

u/ml

2.59

123

Transient ischemic attack

177

1615

0.91

0.63

1.1

2.34

3.54

u/ml

0.92

741

L02BA Anti-estrogens

891

0.86

0.63

1.1

4.27

3.08

u/ml

0.41

404

Other/unspecified disorders of vestibular function

138

1.38

0.62

1.2

1.0

5.45

4.81

u/ml

—

Viral infections of the central nervous system

525

1.18

0.62

1.0

1.1

8.77

5.06

u/ml

0.85

279

Open wound of ankle and foot

776

1.15

0.62

1.0

1.1

6.82

6.15

u/ml

0.12

415

Other disorders of amniotic fluid and membranes

165

1802

0.90

0.62

1.1

3.73

5.25

u/ml

0.89

959

Hyperplasia of prostate

144

735

1.12

0.62

1.0

1.1

3.34

3.22

u/ml

0.04

352

Osteoporosis

766

1.15

0.62

1.1

5.70

4.01

u/ml

0.28

364

Malignant neoplasm of rectum, excluding all cancers (controls excluding all cancers)

347

0.78

0.62

1.1

8.55

3.67

u/ml

0.55

161

Developmental endpoint to exclude non autoimmune-cases from E4_HYTHY_AI_STRICT

280

2597

1.08

0.62

1.0

1.1

3.75

5.37

u/ml

1.47

155

1367

Disorders of optic nerve and visual pathways

761

0.85

0.62

1.1

7.55

6.19

u/ml

0.18

433

Streptococcal septicaemia

391

0.79

0.62

1.0

1.1

4.48

6.48

u/ml

0.40

227

Noonan syndrome

0.00

0.61

0.0

1.0

—

6.81

—

Myocardial infarction, strict

152

1229

0.90

0.61

1.0

2.62

2.76

u/ml

0.06

574

Peripheral arterial reconstruction

290

0.76

0.61

1.1

1.0

1.84

3.83

u/ml

—

114

Nontraumatic intracranial haemmorrhage

609

0.84

0.61

1.1

4.83

4.04

u/ml

0.12

287

Viral agents as the cause of diseases classified to other chapters

165

1.34

0.61

1.0

1.1

3.65

4.93

u/ml

0.18

Follicular cysts of skin and subcutaneous tissue

130

1164

1.12

0.61

1.1

5.28

5.41

u/ml

0.03

585

Erectile dysfunction

187

0.69

0.61

1.0

1.1

0.28

6.66

u/ml

—

Maternal care for known or suspected abnormality of pelvic organs

355

2291

1.07

0.61

1.1

4.52

4.95

u/ml

0.21

173

1179

Conduction disorders

147

1100

1.11

0.61

1.0

1.1

5.46

4.37

u/ml

0.34

566

Anisometropia and aniseikonia

218

1.29

0.60

1.0

1.1

2.44

6.63

u/ml

2.18

123

Benign neoplasm: Endocrine pancreas

0.00

0.60

0.0

1.0

—

11.88

—

Benign neoplasm: Connective and other soft tissue of trunk, unspecified

0.00

0.60

0.0

1.0

—

7.25

—

Extreme obesity with alveolar hypoventilation

163

0.67

0.60

1.2

1.0

7.89

5.26

u/ml

—

Alzheimer’s disease (Late onset)

180

0.71

0.60

1.0

2.51

0.85

u/ml

—

Haemolytic anaemias

183

1.32

0.60

1.1

12.03

6.01

u/ml

0.49

107

Benign neoplasm: Endocrine pancreas

0.00

0.59

0.0

1.0

—

10.96

—

Wide developmental disorders, excluding more controls

567

0.83

0.59

1.1

1.2

3.70

7.50

u/ml

1.16

390

Other mental disorders due to brain damage and dysfunction and to physical disease

311

0.77

0.59

1.0

1.1

7.53

4.54

u/ml

0.26

136

Valvular operations

542

0.83

0.59

1.0

1.1

5.43

5.28

u/ml

0.02

301

Spina bifida

0.00

0.59

0.0

1.0

—

3.57

—

Chronic tubulo-interstitial nephritis

157

1.34

0.59

1.1

4.54

4.51

u/ml

—

Sleep disorders, other/unspecified

309

1.24

0.58

1.2

1.1

7.30

7.34

u/ml

0.00

170

Cardiomyopathies, Primary/intrinsic

454

0.81

0.58

1.1

7.51

5.13

u/ml

0.31

236

Benign neoplasm: Connective and other soft tissue of trunk, unspecified

0.00

0.58

0.0

1.0

—

7.28

—

Acquired absence of limb

0.00

0.58

0.0

1.0

—

8.00

—

Benign neoplasm: Bladder

0.00

0.58

0.0

1.1

—

3.64

—

Benign neoplasm: Bladder

0.00

0.58

0.0

1.0

—

4.47

—

Parkinson's disease, including avohilmo

310

0.77

0.58

1.0

1.09

2.96

u/ml

—

136

Supervision of normal pregnancy

321

1964

0.93

0.58

1.1

5.69

5.72

u/ml

0.01

175

1000

Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk

753

1.14

0.58

1.0

1.1

3.20

4.19

u/ml

0.49

366

Pervasive developmental disorders excl. Autism + Asperger

295

0.76

0.58

1.0

1.3

1.11

7.29

u/ml

6.67

230

Open bite that required surgery (Lefort1 or BSSRO)

1.50

0.57

1.0

1.1

0.87

7.53

u/ml

—

Precocious puberty

0.56

0.57

1.2

13.12

7.40

u/ml

—

338

1.22

0.57

1.1

5.78

8.57

u/ml

0.70

217

Other aneurysm

132

1.37

0.57

1.1

1.0

1.57

4.31

u/ml

—

Cramp and spasm

283

1.24

0.57

1.1

8.55

5.76

u/ml

0.58

159

Diplopia

689

1.15

0.56

1.1

3.75

5.16

u/ml

0.38

344

Scarlet fever

1.56

0.56

1.0

1.1

1.35

5.16

u/ml

—

Other lesions of median nerve

1.51

0.56

1.1

1.0

4.46

4.24

u/ml

—

Other disorders of binocular vision

107

1.41

0.56

1.1

1.0

0.27

7.04

u/ml

—

Unspecified maternal hypertension

133

1.37

0.56

1.1

0.92

4.60

u/ml

—

Ascites

229

0.74

0.55

1.1

0.65

3.80

u/ml

—

111

Primary open-angle glaucoma

713

0.86

0.55

1.0

2.83

2.76

u/ml

0.02

320

Vasculitis limited to skin, not elsewhere classified

107

1.41

0.55

1.2

1.1

10.91

4.35

u/ml

—

Other benign neoplasms of skin

234

2127

1.08

0.55

1.1

3.78

4.82

u/ml

0.52

114

1037

Memory loss

239

1.26

0.55

1.1

1.81

4.69

u/ml

1.45

104

Superficial injury of thorax

105

936

1.12

0.55

1.1

5.37

6.21

u/ml

0.23

490

IgA nephropathy (IgA glomerulonephritis)

116

1.39

0.54

1.0

8.72

8.89

u/ml

—

Polymyalgia rheumatica

262

0.76

0.54

1.0

1.1

1.78

2.83

u/ml

—

115

Parkinson's disease, strict definition

262

0.76

0.54

1.0

1.40

3.19

u/ml

—

112

Superficial injury of head

192

1766

1.09

0.54

1.1

5.61

5.89

u/ml

0.08

113

968

Later onset COPD

287

1.20

0.54

1.0

0.58

2.11

u/ml

1.79

120

Herpesviral keratitis and keratoconjunctivitis

195

1.29

0.54

1.0

1.1

8.39

4.91

u/ml

0.39

Other congenital malformations of face and neck

249

1.25

0.54

1.1

2.83

6.56

u/ml

1.47

148

Effects of other external causes

240

1.26

0.54

1.1

12.52

6.55

u/ml

0.39

138

Aortic aneurysm

551

1.16

0.54

1.0

3.05

4.66

u/ml

0.60

255

Acne vulgaris

133

1205

1.11

0.53

1.1

8.57

7.97

u/ml

0.12

698

Sulfasalazine

208

1923

1.08

0.53

1.0

1.1

5.64

5.45

u/ml

0.05

922

Benign neoplasm: Skin, unspecified

187

1.29

0.53

1.0

1.1

1.22

4.07

u/ml

2.05

103

Benign neoplasm: Skin, unspecified

187

1.29

0.53

1.0

1.1

1.22

4.38

u/ml

2.11

Other anaemias

159

1677

0.91

0.53

1.1

5.62

4.29

u/ml

0.45

848

Volume depletion

338

0.80

0.52

1.1

10.62

6.13

u/ml

0.55

196

Chronic nephritic syndrome

181

0.72

0.52

1.0

9.27

7.04

u/ml

—

Trigeminal neuralgia

286

1.23

0.52

1.0

1.1

1.02

2.94

u/ml

1.87

132

Vertebral, anorectal, cardiavascular, thracheoesophagial, renal and limb anomaly

168

1770

0.92

0.52

1.0

1.1

6.27

6.37

u/ml

0.03

109

1087

Chromosomal abnormalities, not elsewhere classified

368

0.81

0.52

1.0

1.2

4.33

6.04

u/ml

0.40

264

Specific development disorders of scholastic skills

781

1.13

0.52

1.1

7.66

7.75

u/ml

0.01

520

Intracerebral haemorrhage

293

0.78

0.52

1.1

1.0

5.79

4.84

u/ml

—

140

Injuries to the shoulder and upper arm

711

5718

1.04

0.52

1.1

3.74

5.89

u/ml

4.17

356

2996

Carcinoma in situ of skin of other and unspecified parts of face

1.45

0.51

1.0

6.12

2.24

u/ml

—

Acute peritonitis

248

0.76

0.51

1.2

1.1

0.58

4.84

u/ml

4.91

126

Abnormal findings on examination of blood, without diagnosis

259

2262

1.07

0.51

1.1

4.15

5.19

u/ml

0.53

125

1175

Malignant neoplasm of ovary, excluding all cancers (controls excluding all cancers)

259

0.77

0.51

1.0

1.1

2.89

2.36

u/ml

—

130

Lactose intolerance, other/unspecified

206

1.27

0.51

1.0

1.1

6.53

6.78

u/ml

0.02

126

Vestibular neuronitis

391

0.82

0.51

1.1

1.0

6.10

4.26

u/ml

0.32

191

Hodgkin lymphoma

168

0.71

0.50

1.3

1.1

19.46

6.48

u/ml

—

Respiratory and cardiovascular disorders specific to the perinatal period

623

1.14

0.50

1.2

7.11

6.28

u/ml

0.17

464

Event of undetermined intent

519

1.16

0.50

1.1

4.49

6.37

u/ml

0.68

284

Congenital malformations of the respiratory system

180

1.29

0.50

1.2

4.06

7.04

u/ml

0.55

125

Mixed disorders of conduct and emotions, excluding more controls

411

0.82

0.50

1.0

1.1

5.48

8.02

u/ml

0.50

264

Burn and corrosion of head and neck

156

0.70

0.50

1.0

1.1

9.18

7.56

u/ml

—

Disorders of calcium metabolism

269

0.78

0.50

1.1

1.82

5.14

u/ml

—

143

Non-ischemic cardiomyopathy

812

0.89

0.50

1.0

1.1

5.68

3.44

u/ml

0.48

406

Inguinal hernia

431

3061

0.95

0.49

1.1

5.59

6.05

u/ml

0.22

222

1644

Vertical strabismus

198

1.27

0.49

1.1

3.14

5.52

u/ml

0.53

108

Other hearing loss

871

1.12

0.49

1.1

4.86

4.38

u/ml

0.09

407

Congenital malformations of pulmonary and tricuspid valves

166

0.71

0.49

1.1

1.3

10.29

6.65

u/ml

—

128

Gestational [pregnancy-induced] oedema and proteinuria without hypertension

669

0.86

0.49

1.1

3.66

4.58

u/ml

0.26

328

Other facial nerve disorders

136

1.33

0.49

1.4

1.1

10.10

4.24

u/ml

—

Other maltreatment syndromes

268

0.78

0.49

1.2

1.1

8.41

6.68

u/ml

0.10

144

Arthropathic psoriasis

690

0.87

0.49

1.1

4.01

5.07

u/ml

0.15

348

Other and unspecified abdominal hernia

145

1.31

0.49

1.2

1.1

0.99

3.76

u/ml

—

Hydrocephalus

279

0.79

0.49

1.0

1.1

11.28

6.02

u/ml

0.29

155

Viral and other specified intestinal infections

314

2890

1.06

0.48

1.1

6.66

8.01

u/ml

0.47

193

1749

Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck

280

1.22

0.48

1.1

2.41

4.43

u/ml

0.80

132

Personality disorders

309

2911

1.06

0.48

1.1

5.05

6.04

u/ml

0.57

178

1533

Other embolism and thrombosis

586

1.15

0.48

1.1

4.95

4.19

u/ml

0.12

282

Type of accident

250

2339

1.07

0.48

1.1

6.15

6.10

u/ml

0.01

140

1263

Social disorders starting during childhood or adolescence

137

1.33

0.48

1.0

1.2

1.09

6.61

u/ml

3.21

101

Crowding of teeth, including avohilmo

184

1404

1.08

0.48

1.1

8.45

7.71

u/ml

0.22

133

895

Preparatory care for dialysis

155

0.71

0.48

1.0

1.1

6.87

6.03

u/ml

—

Intracranial trauma

655

4696

1.04

0.48

1.1

5.47

6.32

u/ml

0.50

372

2546

Explicit bacterial Sepsis

550

0.85

0.48

1.0

1.1

6.20

6.05

u/ml

0.02

303

Other and unspecified anaemias

158

1662

0.92

0.48

1.1

5.69

4.23

u/ml

0.50

840

Other and unspecified mononeuropathies of lower limb

119

1.35

0.48

1.0

4.25

3.57

u/ml

—

Rheumatic fever incl heart disease

1.40

0.48

1.1

1.0

3.48

7.96

u/ml

—

Other disorders involving the immune mechanism, not elsewhere classified

208

1.26

0.48

1.0

1.1

5.03

7.56

u/ml

0.37

118

SLE, ICD10

200

0.75

0.48

1.2

1.1

7.29

4.57

u/ml

—

103

SLE, strict definition

200

0.75

0.48

1.2

1.1

7.29

4.57

u/ml

—

103

Other secondary gonarthrosis

190

1.27

0.48

1.0

1.1

2.62

4.09

u/ml

0.50

Left ventricular outflow tract obstruction (LVOTO), broad definition

752

0.88

0.48

1.0

1.1

5.52

5.11

u/ml

0.08

435

Cholelithiasis, broad definition with cholecystitis

630

4500

0.96

0.48

1.1

3.49

4.17

u/ml

0.56

288

2169

Ulcerative colitis, NAS

107

1184

0.90

0.47

1.1

5.79

6.44

u/ml

0.15

632

Anterior Iridocyclitis

124

1362

0.91

0.47

1.1

8.56

5.56

u/ml

0.71

685

Other specific arthropathies, wide

102

1.38

0.47

1.1

1.0

2.29

4.20

u/ml

—

Abdominal aortic aneurysm (AAA)

101

1.38

0.47

1.1

1.0

1.59

3.82

u/ml

—

Personal history of other diseases and conditions

166

1525

1.09

0.47

1.1

6.74

6.34

u/ml

0.11

919

Adalimumab

825

0.88

0.47

1.1

1.55

6.21

u/ml

8.31

444

Left ventricular outflow tract obstruction, narrow definition

462

0.84

0.47

1.0

1.2

2.77

7.43

u/ml

2.92

288

Disorders of psychological development

212

1832

1.07

0.46

1.1

6.78

8.08

u/ml

0.45

135

1185

Benign neoplasm of brain and other parts of central nervous system

364

0.82

0.46

1.1

2.68

5.55

u/ml

1.35

203

Thoracic aortic aneurysm

402

1.17

0.46

1.1

1.76

5.67

u/ml

2.31

189

Melanoma in situ

1.39

0.46

1.2

1.0

3.29

2.63

u/ml

—

Hypertension, essential

685

4064

0.96

0.46

1.1

4.59

4.49

u/ml

0.06

334

2014

Nonspecific lymphadenitis

421

1.17

0.46

1.1

6.66

5.78

u/ml

0.13

205

Hypoglycaemia, other or unspecified

482

0.85

0.45

1.1

6.10

5.79

u/ml

0.04

291

Ulcer of lower limb, not elsewhere classified

396

0.83

0.45

1.0

8.51

4.38

u/ml

0.45

189

Pregnancy with abortive outcome

700

3804

0.96

0.45

1.1

4.52

5.53

u/ml

1.07

352

1919

Myocardial infarction, with ST-elevation

396

0.83

0.45

1.0

1.1

2.08

4.20

u/ml

1.18

174

Congenital iodine-deficiency syndrome/hypothyroidism

147

1.30

0.45

1.1

2.38

7.16

u/ml

1.46

Traumatic subarachnoid haemorrhage

103

1.36

0.45

1.0

7.47

7.78

u/ml

—

Postpartum haemorrhage

333

2744

1.06

0.45

1.1

5.47

5.14

u/ml

0.15

151

1398

Bacterial pneumonia (organism specified)

274

2348

1.06

0.45

1.1

5.60

5.53

u/ml

0.02

156

1201

Other diseases of biliary tract

292

1.20

0.45

1.1

1.57

4.10

u/ml

1.06

145

Other endocrine disorders

824

1.11

0.45

1.1

1.2

4.68

6.41

u/ml

0.65

572

Abnormal findings on antenatal screening of mother

127

1162

1.10

0.44

1.1

4.53

6.31

u/ml

0.60

649

Other behavioural and emotional disorders with onset usually occurring in childhood and adolescence

119

1071

1.10

0.44

1.1

6.21

7.29

u/ml

0.29

706

Intrahepatic Cholestasis of Pregnancy (ICP) , incl. ICD-8, excluding more controls

828

1.11

0.44

1.1

3.14

5.59

u/ml

1.20

418

Non-small cell lung cancer, excluding all cancers (controls excluding all cancers)

311

0.82

0.44

1.0

1.1

5.44

2.36

u/ml

—

137

Disorders of globe

1.45

0.44

1.0

1.1

8.58

8.07

u/ml

—

Benign neoplasm: other/unspecified salivary gland

1.45

0.44

1.1

1.0

0.48

4.38

u/ml

—

Disorders of continuity of bone

667

1.13

0.44

1.1

5.52

5.86

u/ml

0.06

343

Asymmetry of jaw

139

1.30

0.44

1.2

1.1

11.56

7.97

u/ml

—

Thrombocytopenia, unspecified

351

0.82

0.44

1.1

1.71

5.18

u/ml

2.71

199

Pneumonia due to other infectious organisms, not elsewhere classified

130

1.31

0.44

1.2

1.0

4.24

6.32

u/ml

—

Disorders of puberty, all

331

1.19

0.44

1.1

1.2

8.14

8.29

u/ml

0.02

232

Benign neoplasm of colon, rectum, anus and anal canal

322

2176

1.06

0.43

1.1

3.01

3.53

u/ml

0.38

151

998

Other and unspecified disorders involving the immune mechanism, not elsewhere classified

193

1.25

0.43

1.0

1.1

5.20

8.06

u/ml

0.37

109

Plantar fascial fibromatosis

545

1.14

0.43

1.1

2.60

4.76

u/ml

1.05

248

Chronic pancreatitis

512

0.86

0.43

1.0

1.1

2.87

4.42

u/ml

0.49

256

Malignant neoplasm of kidney, except renal pelvis, excluding all cancers (controls excluding all cancers)

296

0.81

0.43

1.0

1.1

6.60

3.68

u/ml

—

147

Other disorders starting during childhood or adolescence

118

1070

1.10

0.43

1.1

6.21

6.88

u/ml

0.17

721

Injuries to unspecified part of trunk, limb or body region

668

1.13

0.43

1.1

6.19

5.83

u/ml

0.08

355

Cyst of kidney

184

1.25

0.43

1.1

1.0

3.73

4.05

u/ml

—

Carbimazole or st.post thyroidectomy, condition for graves disease

161

1491

1.08

0.43

1.0

1.1

3.19

4.90

u/ml

1.13

742

Sequelae with surgical and medical care as external cause

106

963

1.10

0.43

1.1

4.23

4.40

u/ml

0.05

477

Perineal laceration during delivery

223

2119

0.94

0.43

1.1

6.61

6.05

u/ml

0.20

109

1115

Injury of unspecified body region

480

1.15

0.43

1.0

1.1

5.70

5.44

u/ml

0.05

271

Graves ophthalmopathy, strict

113

1.33

0.43

1.0

2.23

3.34

u/ml

—

Inflammatory diseases of the central nervous system

543

0.86

0.43

1.1

13.22

5.10

u/ml

1.29

291

Erythema multiforme

113

1.33

0.43

1.2

1.1

5.29

5.46

u/ml

—

Burns and corrosions

134

1232

1.09

0.43

1.1

8.40

6.69

u/ml

0.36

690

Benign neoplasm: Rectum

574

1.13

0.43

1.0

1.1

2.21

3.94

u/ml

0.69

272

Autoimmune diseases

1262

6623

0.97

0.42

1.1

6.50

5.77

u/ml

0.59

666

3569

Burkitt lymphoma

0.00

0.42

0.0

1.1

—

9.62

—

Burkitt lymphoma, excluding all cancers (controls excluding all cancers)

0.00

0.42

0.0

1.1

—

9.62

—

Burkitt lymphoma, helper endpoint

0.00

0.42

0.0

1.1

—

9.62

—

Manic episode

218

0.78

0.42

1.0

1.1

7.16

7.59

u/ml

—

122

Multiple myeloma, Monoclonal gammopathy of undetermined significance (MGUS), excluding all cancers (controls excluding all cancers)

196

0.76

0.42

1.0

0.52

4.67

u/ml

—

Acute alcohol intoxication ICD-9

113

1.33

0.42

1.1

1.82

5.57

u/ml

—

Endometriosis diagnosis and infertility diagnosis occurring together

102

1122

0.91

0.42

1.0

1.1

3.51

4.88

u/ml

0.51

572

Benign neoplasm of other and unspecified endocrine glands

650

1.12

0.42

1.0

1.1

5.76

4.89

u/ml

0.12

327

Retinoblastoma, excluding all cancers (controls excluding all cancers)

0.00

0.42

0.0

1.0

—

9.02

—

Paralytic strabismus

284

0.81

0.42

1.1

2.68

5.65

u/ml

—

150

In situ neoplasms

189

1932

0.93

0.42

1.0

1.1

7.29

4.24

u/ml

1.14

927

Superficial injury of abdomen, lower back and pelvis

133

1223

1.09

0.42

1.1

7.11

6.46

u/ml

0.14

669

Parkinson's disease, excluding more controls

266

0.81

0.42

1.0

1.22

2.54

u/ml

—

115

Persons with potential health hazards related to communicable diseases

493

5097

0.96

0.42

1.1

6.30

6.41

u/ml

0.05

285

2851

Kidney diseases associated to Fabry's disease

0.00

0.42

0.0

1.1

—

4.11

—

Sphingolipidosis, other/unspecified

0.00

0.42

0.0

1.1

—

4.11

—

Benign neoplasm: other/unspecified salivary gland

1.43

0.41

1.1

1.0

0.48

3.97

u/ml

—

Exposure to sunlight

0.00

0.41

0.0

1.1

—

17.96

—

Eccrine sweat disorders

0.00

0.41

0.0

1.1

—

6.16

—

Cerebral palsy and other paralytic syndromes

785

0.89

0.41

1.1

3.25

5.40

u/ml

0.49

428

Other, unspecified and serous retinal detachments

1.36

0.41

1.1

1.0

39.78

6.34

u/ml

—

Fluid overload

0.00

0.41

0.0

1.1

—

6.39

—

Benign neoplasm: Endocrine gland, other/unspecified

0.00

0.41

0.0

1.0

—

1.16

—

Other heart diseases, wide

990

6326

0.97

0.41

1.1

5.92

5.16

u/ml

0.69

496

3337

Other infiltrative disorders of skin and subcutaneous tissue

0.00

0.41

0.0

1.1

—

2.77

—

Disorders of purine and pyrimidine metabolism

0.00

0.41

0.0

1.1

—

10.33

—

Sequelae of poisoning by drugs, medicaments and biological substances

0.00

0.41

0.0

1.1

—

2.36

—

Retinoblastoma

0.00

0.41

0.0

1.1

—

8.21

—

Artificial opening status

250

0.80

0.41

1.1

11.02

5.40

u/ml

—

146

Other and unspecified injuries of wrist and hand

314

1.18

0.41

1.2

1.1

10.47

6.04

u/ml

0.31

180

Cerebral oedema

0.00

0.41

0.0

1.0

—

8.44

—

Other drug-induced secondary parkinsonism

0.00

0.41

0.0

1.1

—

14.66

—

Hodgkin lymphoma, hilmo

161

0.74

0.41

1.2

1.1

19.46

6.14

u/ml

—

Benign neoplasm: Endocrine gland, other/unspecified

0.00

0.41

0.0

1.1

—

1.82

—

Idiopathic peripheral autonomic neuropathy

0.00

0.41

0.0

1.1

—

4.04

—

Sequelae of injuries of head

315

0.82

0.41

1.1

1.49

6.77

u/ml

3.00

170

Malignant neoplasm of gum, excluding all cancers (controls excluding all cancers)

0.00

0.41

0.0

1.1

—

3.88

—

Alport

0.00

0.40

0.0

1.2

—

8.55

—

Other and unspecified disorders of skin and subcutaneous tissue

305

1.18

0.40

1.1

2.65

4.69

u/ml

0.72

145

Malignant neoplasm of renal pelvis, excluding all cancers (controls excluding all cancers)

0.00

0.40

0.0

1.1

—

7.44

—

Other Crohn's disease

653

1.12

0.40

1.1

6.91

6.65

u/ml

0.04

351

Foreign object accidentally left in body during surgical and medical care

0.00

0.40

0.0

1.1

—

2.70

—

Labyrinthitis

0.00

0.40

0.0

1.0

—

9.90

—

Thyrotoxicosis with diffuse goitre

115

1054

1.09

0.40

1.0

1.1

3.25

5.46

u/ml

1.55

529

Malignant neoplasm of cervix uteri, excluding all cancers (controls excluding all cancers)

149

0.74

0.40

1.0

8.09

2.52

u/ml

—

Findings of drugs and other substances, not normally found in blood

0.00

0.40

0.0

1.0

—

7.33

—

Other eating disorders

761

0.89

0.40

1.2

1.1

5.00

6.86

u/ml

0.29

453

Blindness or visual impairment, binocular

0.00

0.40

0.0

1.0

—

7.01

—

Obstructed labour due to maternal pelvic abnormality

108

987

1.10

0.40

1.1

1.74

3.76

u/ml

2.05

436

Unattended death

0.00

0.40

0.0

1.1

—

4.28

—

Maternal care for cervical incompetence

278

1.19

0.40

1.0

1.1

5.78

4.54

u/ml

0.14

133

Placental disorders

1.35

0.40

1.1

1.0

2.80

5.71

u/ml

—

Malignant melanoma

465

0.86

0.40

1.1

2.46

3.13

u/ml

0.21

214

Liveborn infants according to place of birth

198

1.23

0.40

1.1

1.2

0.88

5.52

u/ml

4.57

148

Other complications of labour and delivery, not elsewhere classified

156

1616

0.93

0.40

1.1

5.28

5.70

u/ml

0.14

851

Hyperprolactinaemia

334

1.17

0.40

1.1

5.73

6.47

u/ml

0.07

178

Other disorders of bladder

411

0.85

0.39

1.1

6.46

4.58

u/ml

0.15

200

Ovarian dysfunction

949

0.90

0.39

1.1

1.39

6.19

u/ml

9.31

519

Pseudomembranous colitis

1.44

0.39

1.0

1.1

0.98

2.62

u/ml

—

Internuclear ophthalmoplegia

0.00

0.39

0.0

1.1

—

2.92

—

Typhoid and paratyphoid fevers

0.00

0.39

0.0

1.1

—

3.63

—

Polycystic ovarian syndrome

749

0.89

0.39

1.1

1.87

6.75

u/ml

6.23

419

Haemorrhage, not elsewhere classified

106

1.32

0.39

1.1

5.12

6.84

u/ml

—

Hypoplasia of dental enamel, including avohilmo

300

0.82

0.39

1.2

0.55

6.96

u/ml

9.48

243

Erosion and ectropion of cervix uteri

115

1.31

0.39

1.1

6.92

2.18

u/ml

—

Syphilis

124

1.30

0.39

1.1

2.42

8.79

u/ml

—

Fracture of lumbar spine and pelvis

853

0.90

0.38

1.0

1.1

7.86

4.88

u/ml

0.50

417

Methotrexate

833

0.90

0.38

1.0

1.43

6.02

u/ml

6.43

398

Orchitis and epididymitis

431

0.86

0.38

1.0

1.1

3.27

7.49

u/ml

1.85

240

Other and unspecified disorders of adult personality and behaviour

1.40

0.38

1.2

1.1

0.21

6.42

u/ml

—

Generalized epilepsy

476

1.14

0.38

1.1

6.14

6.34

u/ml

0.03

286

Chronic lymphocytic leukaemia

1.39

0.38

1.2

1.1

—

4.87

—

Other strabismus

247

2329

1.06

0.38

1.1

4.53

6.27

u/ml

1.23

141

1328

Pyogenic arthritis

298

1.18

0.38

1.2

1.1

6.61

7.18

u/ml

0.05

147

Systemic lupus erythematosus

214

0.79

0.38

1.2

1.1

7.29

4.61

u/ml

—

109

Other disorders of skin and subcutaneous tissue

470

4135

1.04

0.38

1.1

5.13

4.80

u/ml

0.16

244

2046

Other noninflammatory disorders of cervix uteri

206

1.22

0.38

1.1

5.84

2.35

u/ml

—

Use of levodopa decarboxylase inhibitor

236

0.80

0.38

1.0

1.14

3.32

u/ml

—

Other and unspecified disorders of psychological development

284

0.82

0.37

1.2

2.20

7.44

u/ml

3.69

219

Chronic respiratory disease originating in the perinatal period

0.61

0.37

1.2

9.08

5.96

u/ml

—

Retinal vascular occlusion

252

1.19

0.37

1.0

6.15

3.00

u/ml

0.35

110

Superficial injury of forearm

905

1.10

0.37

1.1

6.70

6.63

u/ml

0.01

511

Other disorders of glucose regulation and pancreatic internal secretion

589

0.88

0.37

1.1

4.82

5.53

u/ml

0.13

342

Intrahepatic Cholestasis of Pregnancy (ICP) , excluding more controls

781

1.10

0.37

1.1

3.37

5.71

u/ml

1.02

399

Complications following abortion and ectopic and molar pregnancy

170

1.24

0.37

1.1

0.69

2.07

u/ml

—

Malnutrition

143

1.27

0.37

1.3

1.2

1.79

6.26

u/ml

2.15

101

Melanocytic naevi of trunk

872

0.90

0.37

1.1

6.03

5.77

u/ml

0.05

459

Cholelithiasis

606

4400

0.97

0.37

1.1

3.51

4.18

u/ml

0.53

278

2114

Implicit fungal Sepsis

116

1.30

0.37

1.1

7.86

4.59

u/ml

—

Multiple delivery

767

0.90

0.37

1.1

2.54

4.49

u/ml

1.11

393

Reactive arthropathies

591

1.12

0.37

1.0

1.1

9.71

5.38

u/ml

0.71

286

Leisure time condition

145

1349

1.08

0.37

1.1

6.32

6.13

u/ml

0.04

733

Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk

782

1.10

0.36

1.0

1.1

3.20

4.18

u/ml

0.50

381

Vitamin B12 deficiency anaemia

300

0.83

0.36

1.1

1.65

3.61

u/ml

1.11

133

Colorectal cancer

609

0.89

0.36

1.0

1.1

7.06

3.76

u/ml

0.44

275

Fracture of skull and facial bones

155

1660

0.93

0.36

1.1

7.54

6.46

u/ml

0.27

892

Azathioprine

118

1277

0.92

0.36

1.1

6.04

6.60

u/ml

0.13

688

Etanercept

545

0.88

0.36

1.0

1.1

1.94

5.36

u/ml

2.90

302

Benign neoplasm: Skin of other and unspecified parts of face

459

1.13

0.36

1.1

2.90

5.11

u/ml

1.29

232

Benign neoplasm of ovary

907

1.09

0.36

1.0

1.1

2.67

3.37

u/ml

0.30

412

Other symptoms and signs involving the digestive system and abdomen

112

1032

1.09

0.36

1.1

4.38

5.13

u/ml

0.21

531

Osteomyelitis

272

1.18

0.36

1.1

9.82

6.51

u/ml

0.32

145

Infections, IBD-co-morbidities

132

891

1.08

0.36

1.1

3.24

6.25

u/ml

2.17

470

Exclusions for E4_PCOS_BROAD

173

1621

1.07

0.36

1.1

3.81

6.09

u/ml

1.35

946

Lack of expected normal physiological development

510

0.88

0.36

1.1

1.2

7.91

6.58

u/ml

0.20

388

Other disorders of bone density and structure

157

0.76

0.36

1.0

1.1

9.70

7.37

u/ml

—

Acute and subacute iridocyclitis

121

1307

0.92

0.36

1.1

8.56

5.73

u/ml

0.65

647

Malignant neoplasm of endocrine gland

385

0.86

0.36

1.1

3.88

4.75

u/ml

0.23

198

All dysplastic lesions of the vagina

168

0.77

0.36

1.0

1.1

6.73

2.72

u/ml

—

Other and unspecified corneal deformities and disorders

171

1.23

0.36

1.1

8.15

4.67

u/ml

0.31

Other benign neoplasms of connective and other soft tissue

576

0.88

0.35

1.1

4.25

5.24

u/ml

0.27

288

SLE (Finngen)

212

0.80

0.35

1.2

1.1

7.29

4.93

u/ml

—

105

Amenorrhoea

851

1.10

0.35

1.1

3.86

5.84

u/ml

1.23

480

Crohn disease

128

1188

1.08

0.35

1.1

6.87

6.84

u/ml

0.00

636

Myeloproliferative diseases

277

0.83

0.35

1.1

1.0

0.62

4.30

u/ml

4.18

125

Other viral diseases, not elsewhere classified

216

2036

1.06

0.35

1.1

7.25

6.29

u/ml

0.19

110

1186

Vitamin deficiency

245

1.19

0.35

1.2

1.1

9.52

5.57

u/ml

0.81

134

Vitamin deficiency, wide

245

1.19

0.35

1.2

1.1

9.52

5.57

u/ml

0.81

134

Exclusion endpoint for supernumerary teeth

178

0.78

0.35

1.2

1.1

0.84

8.03

u/ml

—

121

Short stature, not elsewhere classified

602

1.11

0.35

1.1

1.2

5.08

5.92

u/ml

0.22

451

Dental pulpitis 3

272

2058

0.95

0.35

1.1

6.85

9.08

u/ml

1.39

173

1313

Graves disease, strict definition

804

1.10

0.35

1.0

1.1

3.30

5.58

u/ml

1.15

414

Other disorders of optic disc

1.38

0.35

1.3

1.1

17.17

6.91

u/ml

—

Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure

490

0.88

0.34

1.1

4.68

5.08

u/ml

0.04

247

Gonarthrosis, primary, with knee surgery

186

1614

0.94

0.34

1.0

1.57

2.70

u/ml

1.69

660

Motorcycle rider injured in other and unspecified transport accidents

566

1.12

0.34

1.2

1.1

8.52

7.56

u/ml

0.14

311

Convalescence

283

1.17

0.34

1.2

1.1

3.94

4.28

u/ml

0.08

141

Missing teeth due to accident, extraction or parodontitis

509

1.12

0.34

1.1

2.86

5.55

u/ml

1.10

236

Injuries to the hip and thigh

278

2423

1.05

0.34

1.1

6.22

5.57

u/ml

0.24

141

1252

Isolated proteinuria

154

1.24

0.34

1.0

1.1

7.36

5.41

u/ml

—

Eustachian salpingitis and obstruction

892

1.09

0.34

1.1

8.11

6.74

u/ml

0.25

513

Other coagulation defects

538

1.12

0.34

1.2

1.1

4.79

5.59

u/ml

0.18

289

Other/unspecified reactive arthropathies

434

1.13

0.33

1.0

1.1

10.82

4.88

u/ml

0.87

229

Other or unspecified ileus, impaction or obstruction

633

1.11

0.33

1.1

1.08

4.34

u/ml

4.24

315

Chronic Coagulation defects

199

0.80

0.33

1.1

0.91

7.62

u/ml

—

113

Recurrent dislocation of patella

644

1.11

0.33

1.1

4.29

6.58

u/ml

0.84

347

Neuromuscular dysfunction of bladder

406

1.13

0.33

1.1

5.38

5.85

u/ml

0.04

208

Other diseases of blood and blood-forming organs

284

1.16

0.33

1.1

3.23

6.03

u/ml

0.75

141

Glaucoma

216

2001

0.95

0.33

1.0

1.1

3.32

3.88

u/ml

0.24

100

946

Retinal vascular disorders

256

1.17

0.33

1.0

6.15

2.98

u/ml

0.35

111

Infectious mononucleosis

128

1193

1.08

0.33

1.1

9.28

7.63

u/ml

0.42

684

Benign neoplasm: Rectum, anus and anal canal

644

1.10

0.33

1.0

1.1

2.45

4.14

u/ml

0.67

300

Abnormal serum enzyme levels

121

1110

1.08

0.32

1.0

1.1

3.37

4.35

u/ml

0.39

558

Other disorders of pigmentation

210

1.19

0.32

1.2

1.1

5.01

6.94

u/ml

0.33

112

Symptoms and signs involving cognition, perception, emotional state and behaviour

848

6102

0.97

0.32

1.1

5.08

5.07

u/ml

0.00

445

3114

Benign neoplasm of brain and other parts of central nervous system

349

0.86

0.32

1.1

2.68

5.18

u/ml

1.10

191

Hallux valgus (acquired)

220

1509

1.06

0.32

1.1

2.48

4.07

u/ml

0.91

100

637

Chronic suppurative otitis media, including avohilmo

626

1.10

0.32

1.1

3.59

6.32

u/ml

1.07

368

Injury of intra-abdominal organs

176

0.79

0.32

1.1

4.94

7.84

u/ml

—

103

Ankylosing spondylitis

607

1.11

0.32

1.0

1.1

4.68

5.68

u/ml

0.14

308

Diseases of liver

204

1932

1.06

0.32

1.1

3.95

4.84

u/ml

0.51

964

Disorders resulting from impaired renal tubular function

154

0.78

0.32

1.0

1.1

5.64

6.38

u/ml

—

Mandibular prognathia

174

1.21

0.32

1.1

1.2

14.55

8.07

u/ml

0.64

120

Degeneration of macula and posterior pole

122

936

1.07

0.32

1.0

1.1

1.51

3.00

u/ml

1.53

410

Other symptoms and signs involving the urinary system

474

1.12

0.32

1.0

1.1

2.45

5.17

u/ml

1.92

241

Sixth [abducent] nerve palsy

110

1.28

0.31

1.0

2.43

5.33

u/ml

—

Pneumonia (excl. viral and due to other infectious organisms not elsewhere classified)

950

6839

0.98

0.31

1.1

5.69

5.42

u/ml

0.19

558

3571

Disorders of speech understanding and production

641

0.90

0.31

1.2

6.21

6.95

u/ml

0.12

442

Maternal care related to the fetus and amniotic cavity and possible delivery problems

590

3364

1.03

0.31

1.1

5.65

5.30

u/ml

0.19

284

1690

Divergent concomitant strabismus

627

1.10

0.31

1.1

3.19

5.60

u/ml

1.12

332

Nonischemic cardiomyopathy

230

0.82

0.31

1.1

6.73

5.95

u/ml

0.10

115

Other specified congenital malformation syndromes affecting multiple systems

272

0.84

0.31

1.1

1.2

1.50

7.31

u/ml

4.41

189

Benign neoplasm of meninges

361

1.14

0.31

1.0

1.1

1.77

3.37

u/ml

0.82

171

Complications of labour and delivery

687

3720

1.03

0.31

1.1

5.54

5.13

u/ml

0.26

331

1861

Antenatal screening

346

2030

0.96

0.31

1.1

5.28

6.01

u/ml

0.35

186

1038

Mixed and other personality disorders

743

1.09

0.31

1.1

2.76

5.87

u/ml

2.66

385

Malignant neoplasm of urinary organs

251

0.84

0.31

1.0

1.1

7.54

4.26

u/ml

—

119

Speech disturbances, not elsewhere classified

315

0.86

0.30

1.0

1.1

3.54

5.96

u/ml

0.57

153

Benign neoplasm: Cerebral meninges

324

1.14

0.30

1.1

1.77

2.89

u/ml

0.53

152

Direct fill therapy

113

1212

0.93

0.30

1.1

3.60

6.46

u/ml

2.40

698

Social phobias

112

1043

1.08

0.30

1.1

5.66

7.43

u/ml

0.58

586

Glomerulonephritis

610

0.90

0.30

1.1

2.92

5.61

u/ml

0.74

350

Foreign body or object entering through skin

457

1.12

0.30

1.1

2.29

6.51

u/ml

3.91

252

Benign neoplasm: Pituitary gland, craniopharyngeal duct

315

1.15

0.30

1.0

1.1

5.07

5.96

u/ml

0.09

167

Benign leiomyoma with endometriosis

829

0.92

0.30

1.1

1.67

2.85

u/ml

1.09

387

Fibrosis and cirrhosis of liver

268

1.16

0.30

1.0

1.46

3.22

u/ml

1.21

133

Malignant neoplasm of mesothelium and soft tissue

120

1.25

0.30

1.1

1.0

4.80

4.31

u/ml

—

Ulcerative rectosigmoiditis

620

0.90

0.30

1.1

5.09

5.79

u/ml

0.09

322

Secondary right heart disease

102

1.28

0.30

1.0

1.1

0.36

3.94

u/ml

—

Malignant neoplasm of kidney, except renal pelvis

239

0.84

0.29

1.1

7.54

4.32

u/ml

—

116

Benign neoplasm of other and unspecified endocrine glands

668

1.09

0.29

1.0

1.1

5.76

4.67

u/ml

0.15

336

Hypotension

372

1.13

0.29

1.1

2.62

4.81

u/ml

1.02

174

Psoriatic and enteropathic arthropathies

807

0.92

0.29

1.1

3.93

5.09

u/ml

0.21

388

Venous complications and haemorrhoids in pregnancy

217

0.83

0.29

1.1

2.48

5.12

u/ml

—

113

Chronic hepatitis, not elsewhere classified

152

0.79

0.29

1.0

0.07

3.78

u/ml

—

Need for other prophylactic measures

382

1.13

0.29

1.1

3.38

5.90

u/ml

1.08

230

Dislocation, sprain and strain of joints and ligaments of elbow

611

1.10

0.29

1.1

7.31

5.97

u/ml

0.18

352

Fentanyl

260

0.84

0.29

1.0

9.39

4.46

u/ml

0.30

120

Reactive arthropathies, FINNGEN

506

1.11

0.29

1.0

1.1

10.13

5.19

u/ml

0.73

258

Infections of breast associated with childbirth

392

1.13

0.29

1.1

3.36

5.34

u/ml

0.44

206

Retention of urine

113

1023

0.93

0.29

1.1

4.12

4.32

u/ml

0.04

508

Other salmonella infections

176

1.20

0.29

1.0

1.1

2.16

5.39

u/ml

—

Other and unspecified iron deficiency

208

1979

1.05

0.28

1.1

8.44

4.94

u/ml

1.08

104

1046

Radial styloid tenosynovitis [de Quervain]

402

1.12

0.28

1.1

1.97

5.98

u/ml

2.68

189

Other dialysis

173

0.81

0.28

1.3

1.1

0.57

7.27

u/ml

—

Encephalitis

173

0.81

0.28

1.1

12.65

4.56

u/ml

—

Anorexia

112

1.26

0.28

1.2

1.1

7.78

6.63

u/ml

—

Additional codes for the location of defect, injury or illness

336

1.13

0.28

1.1

10.17

6.25

u/ml

0.42

187

Other and unspecified injuries of shoulder and upper arm

158

1.21

0.28

1.2

1.1

4.58

7.37

u/ml

0.37

Parkinson's disease, strict definition, excluding more controls

233

0.84

0.28

1.0

1.40

2.38

u/ml

—

100

Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs

374

1.12

0.28

1.1

2.56

4.64

u/ml

0.92

186

Other disorders of binocular movement

214

1.17

0.28

1.2

1.1

0.67

7.63

u/ml

5.38

122

Other diseases of arteries and capillaries

374

1.12

0.28

1.1

1.89

5.16

u/ml

1.67

180

Intrahepatic Cholestasis of Pregnancy (ICP) , incl. ICD-8

854

1.08

0.28

1.1

3.14

5.59

u/ml

1.17

434

Fall on same level

1286

7323

0.98

0.28

1.1

5.27

5.79

u/ml

0.52

715

3861

Colon adenocarcinoma, excluding all cancers (controls excluding all cancers)

248

0.85

0.28

1.0

1.1

0.54

2.81

u/ml

—

112

Cirrhosis of liver, NAS

149

1.21

0.28

1.1

1.0

1.66

5.12

u/ml

1.63

Hypertrichosis

233

1.16

0.28

1.0

1.1

3.95

4.75

u/ml

0.13

121

Other peripheral vascular diseases

441

1.11

0.27

1.1

3.70

5.69

u/ml

0.44

220

Effects of foreign body entering through natural orifice

213

2032

1.05

0.27

1.1

6.49

6.03

u/ml

0.15

116

1139

Other benign neoplasms of connective and other soft tissue

564

0.90

0.27

1.1

4.25

5.50

u/ml

0.35

281

Benign neoplasm: Pituitary gland, craniopharyngeal duct

318

1.13

0.27

1.0

1.1

5.07

6.71

u/ml

0.17

175

Habit and impulse disorders

150

0.80

0.27

1.0

1.1

10.99

8.72

u/ml

—

Other and unspecified mononeuropathies of upper limb

161

0.81

0.27

1.2

1.0

0.42

6.73

u/ml

—

Psoriatic arthropathies, ICD10

626

0.91

0.27

1.1

4.03

4.72

u/ml

0.10

308

ILD medications: azathioprine

118

1257

0.94

0.27

1.1

6.04

6.68

u/ml

0.16

681

Injury of muscle and tendon at wrist and hand level

906

0.93

0.27

1.1

3.13

5.79

u/ml

1.55

469

Non-small cell lung cancer

311

0.87

0.27

1.0

5.44

2.68

u/ml

—

132

Exposure to other specified electric current

113

1.25

0.27

1.0

1.1

6.17

7.27

u/ml

—

Glaucoma suspect

152

1438

1.06

0.27

1.0

1.1

3.69

3.80

u/ml

0.03

680

Gastroduodenal ulcer

757

1.08

0.26

1.1

2.70

3.72

u/ml

0.39

349

Endocarditis

113

1.24

0.26

1.0

1.1

12.85

7.89

u/ml

—

Spondylopathies (FG)

129

1215

1.06

0.26

1.0

1.1

5.82

6.31

u/ml

0.08

619

Benign neoplasm: Skin of other and unspecified parts of face

471

1.11

0.26

1.1

2.90

4.99

u/ml

1.20

237

Cholesteatoma of middle ear

193

0.83

0.26

1.1

5.98

6.21

u/ml

—

Other disorders of ear

750

4876

1.02

0.26

1.1

4.93

u/ml

0.00

371

2492

Melanocytic naevi of lower limb, including hip

300

1.14

0.26

1.1

5.55

6.39

u/ml

0.11

157

Dental pulpitis 3, only avohilmo

253

1926

0.96

0.26

1.1

6.90

9.43

u/ml

1.57

159

1228

Other ulcerative colitis

468

0.90

0.26

1.1

9.21

5.78

u/ml

0.42

255

Use of memantine

224

0.85

0.26

1.0

0.45

1.31

u/ml

—

Use of other anti-dementia drugs

224

0.85

0.26

1.0

0.45

1.31

u/ml

—

Contact with nonpowered hand tool

253

1.15

0.26

1.1

12.14

6.93

u/ml

0.37

134

Corns and callosities

310

0.87

0.26

1.1

10.63

4.72

u/ml

0.46

147

Pyoderma

1.28

0.26

1.1

1.0

0.61

6.73

u/ml

—

Other lack of coordination

1.30

0.26

1.0

1.1

3.69

7.27

u/ml

—

Thyrotoxicosis with toxic multinodular goitre

206

1.17

0.26

1.0

1.48

2.94

u/ml

0.66

Acute appendicitis, with complications

116

1234

0.94

0.26

1.1

3.42

5.06

u/ml

0.67

599

Hyphaema and other vascular disorders of iris and ciliary body

0.67

0.26

1.2

1.0

14.31

8.62

u/ml

—

Endometriosis ASRM stages 3,4

201

1919

1.05

0.26

1.1

4.52

4.64

u/ml

0.04

106

960

Colon adenocarcinoma

246

0.85

0.26

1.0

0.54

2.97

u/ml

—

101

Visual impairment including blindness (binocular or monocular)

299

0.87

0.26

1.0

1.1

5.29

6.94

u/ml

0.29

172

Fracture of foot, except ankle

227

2174

1.05

0.26

1.1

5.33

6.39

u/ml

0.48

131

1160

Other other unspecified disorders of the circulatory system

149

0.80

0.25

1.1

0.22

6.45

u/ml

—

Unspecified urinary incontinence

387

1.11

0.25

1.0

1.1

5.73

4.73

u/ml

0.20

199

Respiratory tuberculosis, confirmed and not-confirmed

114

1.23

0.25

1.1

4.09

5.27

u/ml

—

Respiratory tuberculosis

114

1.23

0.25

1.1

4.09

5.27

u/ml

—

Gonococcal infection

179

1.18

0.25

1.0

1.1

6.83

7.12

u/ml

0.03

Elevated blood glucose level

483

1.10

0.25

1.2

1.1

8.47

5.78

u/ml

0.37

274

Pedal cyclist injured in noncollision transport accidents

922

0.93

0.24

1.1

5.53

6.28

u/ml

0.16

492

Other and unspecified glaucoma

142

1.20

0.24

1.0

6.13

3.40

u/ml

—

Diabetic retinopathy

120

804

0.94

0.24

1.0

1.1

6.62

3.86

u/ml

0.75

361

Bacterial pneumonia, not elsewhere classified

243

2065

1.04

0.24

1.0

1.1

4.63

5.45

u/ml

0.38

139

1062

Bacterial meningitis

191

0.84

0.24

1.1

15.55

5.88

u/ml

0.54

Scissor bite

492

1.10

0.24

1.1

15.03

9.98

u/ml

0.71

331

Melanocytic naevi of upper limb, including shoulder

133

1.21

0.24

1.1

9.98

4.38

u/ml

—

Coxarthrosis [arthrosis of hip](FG)

252

1896

0.96

0.24

1.1

2.90

3.50

u/ml

0.27

111

825

Gender identity disorders

169

0.82

0.24

1.0

1.1

10.98

9.81

u/ml

—

100

117

1104

1.06

0.24

1.1

6.74

5.74

u/ml

0.23

556

Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs

379

1.11

0.24

1.1

2.56

4.40

u/ml

0.79

189

Sequelae of other and unspecified infectious and parasitic diseases

412

0.90

0.23

1.1

2.65

4.94

u/ml

0.85

201

Other fall from one level to another

205

2137

0.96

0.23

1.1

5.73

6.71

u/ml

0.33

112

1241

Polycystic ovarian syndrome, broad definition

159

1515

1.05

0.23

1.1

5.39

5.87

u/ml

0.16

820

Specific personality disorders

265

2554

1.04

0.23

1.1

5.26

6.11

u/ml

0.40

153

1342

Pyothorax

115

1.22

0.23

1.0

22.91

7.19

u/ml

—

Hyperkalaemia

115

1.22

0.23

1.0

6.41

5.34

u/ml

—

Other disorders of fluid, electrolyte and acid-base balance

119

1214

0.94

0.23

1.1

2.02

4.24

u/ml

2.07

619

Benign neoplasm: Descending colon

171

1.17

0.23

1.1

1.0

3.17

3.55

u/ml

0.05

Corneal scars and opacities

106

1.23

0.23

1.1

5.78

6.10

u/ml

—

Benign neoplasm: Connective and other soft tissue of upper limb, including shoulder

237

1.14

0.23

1.0

1.1

4.47

4.24

u/ml

0.04

121

Dental caries 1 and operation codes, only avohilmo

334

1623

1.04

0.23

1.1

6.57

6.17

u/ml

0.13

178

893

Congenital malformations of ovaries, fallopian tubes and broad ligaments

582

1.08

0.23

1.1

8.58

5.31

u/ml

0.48

304

Other sexually transmitted chlamydial diseases

931

1.07

0.23

1.1

6.01

7.36

u/ml

0.35

537

Other pulmonary heart/vessel disease

134

1.20

0.23

1.0

1.1

0.41

4.65

u/ml

—

Brachial plexus disorders

805

1.07

0.22

1.1

3.79

5.63

u/ml

0.99

405

Melanocytic naevi of trunk

846

0.93

0.22

1.1

6.03

5.98

u/ml

0.01

442

Placenta praevia

525

0.91

0.22

1.0

1.1

10.08

5.25

u/ml

0.38

277

Gingival hyperplasia

274

0.87

0.22

1.0

1.2

2.98

5.90

u/ml

0.95

169

Other metabolic disorders

105

990

1.06

0.22

1.0

1.1

3.69

4.99

u/ml

0.57

519

UC patients in KELA-register (code 208), prior to 1994

189

0.85

0.22

1.0

1.1

1.15

3.90

u/ml

—

Benign neoplasm: Cerebral meninges

333

1.11

0.22

1.1

1.77

3.14

u/ml

0.70

164

Androgen resistance syndrome

0.00

0.22

0.0

1.0

—

3.18

—

Use of interferon beta-1a

210

0.85

0.22

1.0

1.1

4.42

5.45

u/ml

—

102

Bacterial, viral and other infectious agents

709

1.07

0.22

1.0

1.1

3.65

5.76

u/ml

0.98

383

Other assisted single delivery

199

0.85

0.22

1.0

1.1

0.72

5.54

u/ml

2.89

101

Allergic purpura

229

1.14

0.21

1.1

6.27

8.83

u/ml

0.34

120

Traumatic amputation of shoulder and upper arm

0.00

0.21

0.0

1.2

—

0.92

—

Dislocations, sprains and strains involving multiple body regions

0.00

0.21

0.0

1.1

—

1.40

—

Supervision of high-risk pregnancy

295

1844

0.97

0.21

1.1

6.64

5.33

u/ml

0.55

140

938

Transitory endocrine and metabolic disorders specific to fetus and newborn

412

1.10

0.21

1.2

7.47

6.19

u/ml

0.16

315

Opening and dilatation of root channel of tooth

513

0.91

0.21

1.2

1.1

3.09

5.87

u/ml

1.26

270

Disorders of copper metabolism

0.00

0.21

0.0

1.0

—

27.66

—

Other sideroblastic anaemias

0.00

0.21

0.0

1.0

—

4.82

—

Benign neoplasm: Scrotum

0.00

0.21

0.0

1.0

—

11.26

—

Benign neoplasm: Eye, unspecified

0.00

0.21

0.0

1.1

—

2.20

—

Tuberculosis, IBD comorbidity

163

1.17

0.21

1.1

1.0

5.47

6.38

u/ml

—

Malignant neoplasm of ureter, excluding all cancers (controls excluding all cancers)

0.00

0.21

0.0

1.0

—

5.04

—

Pediculosis, acariasis and other infestations

430

1.09

0.21

1.1

1.30

6.10

u/ml

5.81

224

Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions

0.00

0.21

0.0

1.1

—

4.28

—

Recurrent cholesteatoma of postmastoidectomy cavity

0.00

0.21

0.0

1.0

—

2.77

—

0.00

0.21

0.0

1.1

—

1.82

—

Carcinoma in situ of prostate

0.00

0.21

0.0

1.1

—

2.25

—

Papillary adenocarcinoma of thyroid gland, excluding all cancers (controls excluding all cancers)

363

1.10

0.21

1.1

3.61

4.77

u/ml

0.41

189

Animal-rider or occupant of animal-drawn vehicle injured in transport accident

126

1.20

0.21

1.1

6.03

4.83

u/ml

—

Myositis

1.23

0.21

1.3

1.0

2.35

7.10

u/ml

—

Other malignant neoplasms of skin (=non-melanoma skin cancer)

159

1313

0.96

0.21

1.1

3.81

2.63

u/ml

0.47

564

Artrosis, including avohilmo

766

4118

1.02

0.21

1.1

4.95

4.53

u/ml

0.22

376

2026

Benign neoplasm: Connective and other soft tissue of upper limb, including shoulder

239

1.13

0.21

1.0

1.1

4.47

4.58

u/ml

0.02

126

Pregnancy examination and test

274

1653

1.04

0.21

1.1

6.48

5.87

u/ml

0.23

150

878

Abnormal spermatozoa

258

1.12

0.21

1.0

1.1

4.90

5.05

u/ml

—

125

Rare circulating lymphoid malignancy, excluding all cancers (controls excluding all cancers)

177

0.85

0.21

1.1

1.2

3.23

8.88

u/ml

—

124

Lung diseases due to external agents

440

1.09

0.21

1.1

3.45

5.70

u/ml

0.34

220

Systemic lupus erythematosus, unspecified

177

0.85

0.21

1.2

1.1

7.29

3.85

u/ml

—

Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function

0.00

0.21

0.0

1.1

—

1.48

—

Inflammatory bowel disease, strict (require KELA)

215

2232

0.96

0.21

1.1

7.40

6.48

u/ml

0.28

1224

Tuberculosis

126

1.19

0.21

1.1

4.09

5.42

u/ml

—

Other hyperalimentation

0.00

0.21

0.0

1.1

—

3.46

—

Thromboangiitis obliterans

0.00

0.21

0.0

1.1

—

8.17

—

Benign neoplasm: Scrotum

0.00

0.21

0.0

1.1

—

9.46

—

Benign neoplasm: Eye, unspecified

0.00

0.21

0.0

1.1

—

2.11

—

Basal cell carcinoma

164

1365

0.96

0.21

1.1

2.60

2.55

u/ml

0.02

588

Malignant neoplasm of hypopharynx, excluding all cancers (controls excluding all cancers)

0.00

0.21

0.0

1.1

—

5.46

—

Pneumonitis due to solids and liquids

230

0.87

0.21

1.1

5.76

5.84

u/ml

0.00

124

Diverticular disease of intestine

399

2577

1.03

0.21

1.1

1.76

3.47

u/ml

4.78

176

1180

Disorders of adult personality and behaviour

325

3154

1.03

0.21

1.1

5.38

6.24

u/ml

0.45

186

1668

ILD medications: immunosuppressive drugs

524

4908

1.02

0.20

1.1

5.20

5.43

u/ml

0.13

284

2471

Benign neoplasm of ovary

935

1.06

0.20

1.0

1.1

2.67

3.03

u/ml

0.14

440

Other disorders of nervous system

272

0.88

0.20

1.1

1.05

4.86

u/ml

—

130

Use of glatiramer acetate

166

0.84

0.20

1.0

1.1

2.53

4.25

u/ml

—

IBD patients in KELA-register

215

2231

0.96

0.20

1.1

7.40

6.59

u/ml

0.24

1224

Male infertility

412

1.09

0.20

1.1

10.77

8.44

u/ml

0.20

241

Sensorineural hearing loss

429

2924

1.03

0.20

1.1

4.18

4.43

u/ml

0.07

188

1383

Other disorders of the genitourinary system

470

0.91

0.20

1.2

1.0

2.66

u/ml

0.00

216

Fetus and newborn affected by maternal complications of pregnancy

193

1.15

0.20

1.1

1.3

5.81

6.72

u/ml

0.07

149

Postpartum haemorrhage due to retained placenta

143

1366

1.05

0.20

1.0

1.1

5.64

5.31

u/ml

0.07

691

Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified

282

0.89

0.20

1.0

1.1

0.97

3.83

u/ml

—

140

Erectile dysfunction, exclusion

0.00

0.20

0.0

1.1

—

4.70

—

Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease

0.00

0.20

0.0

1.1

—

6.38

—

Other disorders of choroid

1.25

0.20

1.3

1.0

44.55

5.84

u/ml

—

Any mental disorder, or suicide (or attempt), or psychic disorders complicating pregnancy, partum or puerperum or nerve system disorders, excluding more controls

295

3042

0.97

0.20

1.1

6.08

5.92

u/ml

0.05

142

1570

Agoraphobia

355

0.90

0.20

1.1

2.80

7.63

u/ml

1.92

194

Other obstructed labour

635

0.93

0.20

1.1

3.41

5.01

u/ml

0.44

315

Chronic periapical parodontitis

115

1210

0.95

0.20

1.1

3.38

5.32

u/ml

0.68

606

Fracture of lower leg, including ankle

410

4189

0.97

0.20

1.1

5.21

5.61

u/ml

0.17

224

2134

Benign neoplasm: Rectum, anus and anal canal

664

1.07

0.20

1.0

1.1

2.45

3.69

u/ml

0.46

310

Rare circulating lymphoid malignancy

176

0.85

0.20

1.1

1.2

3.23

8.67

u/ml

—

121

Wet age-related macular degeneration

217

1.13

0.20

1.0

0.13

1.35

u/ml

4.01

Dental pulpitis 2

680

3411

1.02

0.20

1.1

5.43

5.53

u/ml

0.05

364

1743

Visual field defects

365

0.90

0.20

1.0

1.1

1.78

4.73

u/ml

1.40

182

Convulsions, not elsewhere classified

219

2240

0.96

0.19

1.1

7.36

7.01

u/ml

0.10

121

1309

Abnormal findings on examination of urine, without diagnosis

231

1.13

0.19

1.0

1.1

5.87

6.11

u/ml

0.02

125

Other adrenocortical overactivity

1.23

0.19

1.0

1.2

5.46

6.44

u/ml

—

Carcinoma in situ of skin of other and unspecified parts of face

1.21

0.19

1.0

6.12

1.96

u/ml

—

Blood alcohol or alcohol intoxication level

186

0.86

0.19

1.0

1.1

9.44

8.21

u/ml

—

109

Glaucoma secondary to other eye disorders

146

1.17

0.19

1.1

1.0

5.16

5.39

u/ml

—

Colectomy operation

613

0.93

0.19

1.1

3.41

4.56

u/ml

0.35

294

Intestinal adhesions without obstruction

279

1.11

0.19

1.0

1.1

6.80

3.29

u/ml

0.31

143

Benign neoplasm of meninges

375

1.09

0.19

1.0

1.1

1.77

3.69

u/ml

1.08

182

Deep endometriosis

753

1.06

0.19

1.1

4.85

5.38

u/ml

0.12

391

Torsion of ovary, ovarian pedicle and fallopian tube

203

1.14

0.19

1.1

4.94

4.77

u/ml

0.02

111

Unspecified haematuria

195

1609

1.04

0.19

1.1

5.63

5.01

u/ml

0.20

808

Essential (haemorrhagic) thrombocythaemia

118

1.19

0.19

1.1

1.0

0.69

4.35

u/ml

—

Melanocytic naevi of upper limb, including shoulder

137

1.17

0.19

1.1

9.98

4.36

u/ml

—

ICD-8 DM (Sub-endpoint used for defining DM endpoints)

318

1.10

0.19

1.0

1.1

5.97

5.11

u/ml

0.11

154

Hyperfunction of pituitary gland

482

1.08

0.19

1.1

4.79

7.13

u/ml

0.34

270

Otosclerosis

318

1.10

0.18

1.0

1.1

0.78

3.37

u/ml

2.81

145

Hypokalaemia

482

1.08

0.18

1.1

1.87

5.37

u/ml

2.97

260

Assault by bodily force

817

0.94

0.18

1.1

4.74

6.61

u/ml

0.51

441

Inflammatory bowel disease

278

2863

0.97

0.18

1.1

6.50

6.08

u/ml

0.14

127

1548

Anxious personality disorder

185

0.86

0.18

1.0

1.1

8.37

8.66

u/ml

0.02

107

Postpartum hemorraghe, all women as controls

333

3228

1.03

0.18

1.1

5.47

5.03

u/ml

0.20

151

1644

Primary open-angle glaucoma, strict

579

0.93

0.18

1.0

1.59

2.63

u/ml

0.76

255

Systemic sclerosis (FG)

100

1.20

0.18

1.0

1.1

0.93

3.10

u/ml

—

Other arthritis (FG)

228

2355

0.97

0.18

1.1

6.04

5.52

u/ml

0.16

120

1198

Superficial injury of neck

166

1.15

0.18

1.2

1.1

5.87

8.49

u/ml

—

Neovascular glaucoma

147

1.16

0.18

1.1

1.0

5.16

5.05

u/ml

—

Intrahepatic Cholestasis of Pregnancy (ICP)

814

1.06

0.18

1.1

3.37

5.80

u/ml

1.05

414

Nephrotic syndrome

237

0.88

0.17

1.3

1.1

0.55

7.35

u/ml

—

159

Other specified and unspecified personality disorders

834

1.06

0.17

1.1

4.69

6.21

u/ml

0.39

436

Other disorders of male genital organs

233

1.12

0.17

1.0

1.1

4.20

10.43

u/ml

2.15

136

Injury of eye and orbit

127

1216

1.05

0.17

1.1

9.00

6.49

u/ml

0.37

660

Pedal cyclist injured in other and unspecified transport accidents

854

1.05

0.17

1.1

5.77

6.44

u/ml

0.15

450

Psoriatic arthropathies

630

0.94

0.17

1.1

3.88

5.35

u/ml

0.23

294

Optic atrophy

110

1.19

0.17

1.0

1.1

8.25

9.28

u/ml

—

Chronic ulcer of skin, not elsewhere classified

205

0.88

0.17

1.1

1.28

6.68

u/ml

2.71

Seronegative rheumatoid arthritis

568

0.93

0.17

1.1

2.98

3.96

u/ml

0.33

262

Autism

392

0.92

0.17

1.1

4.82

8.49

u/ml

0.69

259

Foreign body in ear

129

1.17

0.17

1.0

1.1

8.04

6.32

u/ml

—

Other pleural conditions

224

1.12

0.17

1.1

1.19

4.78

u/ml

2.73

108

Assault

135

1406

0.96

0.17

1.1

5.59

7.42

u/ml

0.59

770

Cellulitis of external ear

0.73

0.17

1.0

1.1

7.81

7.32

u/ml

—

Cholangitis (primary sclerosing, PSC)

278

0.90

0.17

1.0

1.1

3.74

4.88

u/ml

0.23

157

Follow-up care involving plastic surgery

186

1.13

0.17

1.1

2.75

3.18

u/ml

—

Distal bite

656

1.06

0.16

1.1

10.14

8.45

u/ml

0.27

430

Tuberculosis, wide

167

1.14

0.16

1.1

1.0

5.47

6.22

u/ml

—

Causalgia

101

1.19

0.16

1.0

21.44

5.46

u/ml

—

Benign leiomyoma with endometriosis

803

0.95

0.16

1.1

1.67

3.12

u/ml

1.36

379

Weight loss

534

1.07

0.16

1.1

3.08

5.06

u/ml

0.98

300

Cardiomyopathy

731

0.94

0.16

1.1

6.71

4.62

u/ml

0.47

384

Somnolence, stupor and coma

204

0.88

0.16

1.1

2.72

6.98

u/ml

—

107

Dental caries

225

2163

1.03

0.16

1.2

1.1

5.38

6.25

u/ml

0.32

144

1229

Viral warts

857

1.05

0.16

1.1

6.35

6.21

u/ml

0.02

471

Inguinal hernia, bilateral

331

1.09

0.16

1.0

1.1

4.15

6.13

u/ml

0.26

160

Pedal cyclist injured in collision with motor vehicle

235

1.11

0.15

1.1

6.68

7.03

u/ml

0.05

132

Chronic suppurative otitis media

506

1.07

0.15

1.1

3.86

6.49

u/ml

0.74

287

Malignant neoplasm of thyroid gland

349

0.92

0.15

1.1

3.88

5.25

u/ml

0.39

173

Fungal Sepsis

130

1.16

0.15

1.1

7.86

5.96

u/ml

—

Angina pectoris

238

1561

1.03

0.15

1.1

1.0

3.98

2.69

u/ml

0.52

714

Deposits [accretions] on teeth

714

0.95

0.15

1.2

5.23

6.35

u/ml

0.22

473

Procreative management

406

3352

1.02

0.15

1.1

5.87

6.27

u/ml

0.20

244

1883

Certain zoonotic bacterial diseases

0.76

0.15

1.0

—

6.95

—

Anaemias

318

2166

0.98

0.15

1.1

7.43

5.60

u/ml

0.73

173

1249

Other problems related to primary support group, including family circumstances

177

1670

1.03

0.15

1.1

3.24

6.37

u/ml

3.88

1037

Cyst of Bartholin Gland

303

1.09

0.15

1.1

3.92

3.67

u/ml

0.05

153

Melanocytic naevi of scalp and neck

161

0.87

0.15

1.1

16.80

8.72

u/ml

—

Transitory disorders of carbohydrate metabolism specific to fetus and newborn

402

1.08

0.15

1.2

7.94

6.19

u/ml

0.22

308

Postprocedural endocrine and metabolic disorders, not elsewhere classified

898

1.05

0.15

1.0

1.1

3.62

5.37

u/ml

0.76

461

Melanocytic naevi of lower limb, including hip

313

1.09

0.15

1.1

5.55

6.00

u/ml

0.06

175

Benign neoplasm: Adrenal gland

255

1.10

0.15

1.0

1.1

8.23

3.55

u/ml

0.34

116

Ulcerative enterocolitis

207

1.11

0.15

1.1

6.36

5.30

u/ml

0.08

102

Hydrocele

451

0.93

0.15

1.1

4.94

7.81

u/ml

0.61

245

Other psoriatic arthropathies

605

0.94

0.15

1.1

4.03

4.64

u/ml

0.08

295

Hypertrophic scar

488

1.07

0.15

1.1

9.45

5.40

u/ml

0.54

268

Assault by sharp object

129

0.85

0.15

1.0

1.1

2.52

8.33

u/ml

—

Mandibular retrognathia

827

0.95

0.14

1.1

6.23

7.70

u/ml

0.29

490

Dental caries 3 and operation codes, only avohilmo

404

1987

1.02

0.14

1.1

6.60

6.33

u/ml

0.10

221

1098

Other disorders originating in the perinatal period

285

1.10

0.14

1.2

0.57

5.71

u/ml

7.29

226

Motor disorders

438

0.93

0.14

1.1

1.2

4.63

6.67

u/ml

0.44

336

Burns and corrosions of external body surface, specified by site

100

958

1.04

0.14

1.1

8.04

6.68

u/ml

0.27

531

Salpingitis and oophoritis

108

1125

0.96

0.14

1.0

1.1

3.73

4.03

u/ml

0.08

504

Toxic effect of ethanol

337

0.92

0.14

1.0

1.1

4.64

6.78

u/ml

0.28

182

Dental pulpitis 4

1201

6310

0.99

0.14

1.1

4.88

6.19

u/ml

2.06

629

3324

Dental pulpitis 1

1201

6311

0.99

0.14

1.1

4.88

6.19

u/ml

2.06

629

3325

Injuries to the elbow and forearm

660

5873

1.02

0.14

1.1

6.41

6.05

u/ml

0.19

373

3114

Injuries to the head

1161

7473

1.01

0.14

1.1

6.43

5.55

u/ml

0.77

664

3913

Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium

482

4292

0.98

0.14

1.1

2.79

4.78

u/ml

5.00

220

2099

Cholangitis (primary sclerosing, PSC), with reimbursement 202

139

0.86

0.14

1.1

6.36

5.45

u/ml

—

Bicuspidal aortic valve syndrome

233

0.90

0.14

1.0

1.1

3.09

7.60

u/ml

—

140

Early complications of trauma

233

0.90

0.14

1.0

1.1

1.82

7.07

u/ml

2.99

122

!Aliquae complicationes praecoces traumatis

233

0.90

0.14

1.0

1.1

1.82

7.07

u/ml

2.99

122

Contact with sharp glass

357

0.92

0.14

1.1

3.50

6.04

u/ml

0.72

196

Pneumonia, organism unspecified

858

6122

1.01

0.14

1.1

5.60

5.18

u/ml

0.32

503

3194

Other abnormal findings of blood chemistry

208

1.11

0.14

1.0

1.1

2.77

5.21

u/ml

0.71

105

Iron deficiency anaemia secondary to blood loss (chronic)

675

0.95

0.14

1.1

5.66

5.05

u/ml

0.08

328

All dysplastic lesions of the cervix uteri

309

3016

1.02

0.14

1.1

5.31

4.79

u/ml

0.23

145

1536

Other disorders of gingiva or/and edentulous alveolar ridge

367

0.93

0.14

1.0

1.2

2.78

5.43

u/ml

1.23

220

Dental pulpitis 2, only avohilmo

687

3463

1.02

0.14

1.1

5.38

5.52

u/ml

0.07

367

1768

Autism spe, excluding more controls

377

0.93

0.14

1.1

4.82

8.08

u/ml

0.59

248

Superficial injuries involving multiple body regions

170

0.88

0.13

1.1

8.57

9.16

u/ml

—

Hypermetropia

734

1.05

0.13

1.2

1.1

2.40

6.91

u/ml

4.53

463

Other congenital malformations of male genital organs

180

0.88

0.13

1.3

1.2

7.95

7.75

u/ml

0.01

139

Malignant neoplasm of endocrine gland, excluding all cancers (controls excluding all cancers)

490

0.94

0.13

1.1

3.36

4.77

u/ml

0.61

260

Hyperkinetic disorders (excl. ADHD)

341

1.08

0.13

1.2

5.26

8.68

u/ml

0.51

243

Coxarthrosis

242

1683

0.97

0.13

1.1

3.00

3.49

u/ml

0.20

107

718

Follow-up examination after treatment for malignant neoplasms

284

0.92

0.13

1.1

1.0

1.11

4.42

u/ml

—

113

Spontaneous abortion

501

3350

1.02

0.13

1.1

3.83

5.15

u/ml

1.28

229

1671

Idiopathic gout

201

0.89

0.13

1.1

1.0

2.87

4.31

u/ml

—

Psychotic depression

422

1.07

0.13

1.0

1.1

2.82

6.85

u/ml

1.76

239

Other noninfective disorders of lymphatic vessels and lymph nodes

180

0.89

0.13

1.2

1.1

6.03

4.52

u/ml

—

Other disorders of kidney and ureter

510

0.94

0.13

1.1

4.56

4.77

u/ml

0.03

255

Artificial joint operation, meniscal resection

616

4036

1.02

0.13

1.1

3.49

4.70

u/ml

1.64

300

1920

Basal cell carcinoma, including avohilmo

174

1411

0.97

0.13

1.1

2.50

2.62

u/ml

0.06

601

Myeloproliferative diseases (CML excluded)

232

0.90

0.13

1.1

1.0

0.62

3.92

u/ml

3.57

105

Other osteochondrodysplasias

1.18

0.13

1.1

1.2

3.47

4.34

u/ml

—

Maternal care for known or suspected malpresentation of fetus

266

2029

0.98

0.13

1.1

4.34

4.99

u/ml

0.31

131

1070

Arthropod-borne viral fevers and viral haemorrhagic fevers

520

1.06

0.13

1.1

13.37

5.32

u/ml

0.43

251

Burn and corrosion of wrist and hand

345

0.93

0.13

1.2

1.1

12.16

5.85

u/ml

0.68

202

Meningitis

314

0.92

0.13

1.1

15.67

5.33

u/ml

1.06

166

Labour and delivery complicated by umbilical cord complications

468

0.94

0.12

1.0

1.1

3.24

5.40

u/ml

0.93

232

All dysplastic lesions of the vulva

283

0.92

0.12

1.1

4.46

3.46

u/ml

—

136

Other infectious diseases

355

0.93

0.12

1.0

1.1

7.63

5.49

u/ml

0.29

184

Bell's palsy

717

1.05

0.12

1.1

5.86

5.64

u/ml

0.03

361

Melanocytic naevi, other sites/unspecified

531

1.06

0.12

1.1

3.14

5.60

u/ml

1.41

277

Strabismus

265

2588

1.02

0.12

1.1

4.43

5.96

u/ml

1.11

148

1467

Non-invasive ventilation

168

1534

1.03

0.12

1.1

2.89

5.27

u/ml

2.01

803

Paroxysmal tachycardia

187

1623

0.97

0.12

1.1

4.50

5.60

u/ml

0.48

857

Heart failure and bmi 25plus

104

744

0.96

0.12

1.0

1.1

5.28

3.02

u/ml

0.59

327

Ankylosing spondylitis, ICD10

639

1.05

0.12

1.0

1.1

4.68

5.30

u/ml

0.09

323

Tooth eruption problems

233

2254

1.02

0.12

1.1

7.41

7.80

u/ml

0.13

150

1361

Other and unspecified psoriasis

307

1.08

0.12

1.2

1.1

3.14

6.13

u/ml

0.59

154

Other and unspecified disease of Bartholin gland

133

1.13

0.12

1.3

1.1

0.53

2.81

u/ml

—

Polyhydramnios

522

1.06

0.12

1.0

1.1

3.28

5.74

u/ml

0.77

283

Disorders of puberty

288

1.08

0.12

1.1

9.66

8.95

u/ml

0.07

202

Malignant neoplasm of intrahepatic ducts, biliary tract and gallbladder, excluding all cancers (controls excluding all cancers)

137

0.88

0.12

1.0

1.1

4.12

5.71

u/ml

—

Arterial embolism and thrombosis

133

1.13

0.12

1.0

6.75

6.33

u/ml

—

Specific developmental disorder of motor function

427

0.94

0.11

1.1

1.2

4.63

7.84

u/ml

0.79

330

Complications of the puerperium, not elsewhere classified

454

1.06

0.11

1.0

1.1

3.04

5.41

u/ml

1.63

237

Other cataract

182

1446

0.97

0.11

1.1

6.57

3.89

u/ml

0.48

680

Unspecified behavioural syndromes associated with physiological disturbances and physical factors +Physiological and behavioural factors associated with disorders of diseases classified elsewhere

201

1.10

0.11

1.1

1.2

5.47

9.12

u/ml

0.40

130

Coagulation defects, purpura and other haemorrhagic conditions

142

1379

1.03

0.11

1.1

6.72

6.08

u/ml

0.09

743

Toxic effects of substances chiefly nonmedicinal as to source

955

1.04

0.11

1.1

5.88

6.85

u/ml

0.22

523

Open wound of forearm

660

1.05

0.11

1.1

2.26

5.91

u/ml

2.41

339

Filling of root of tooth

172

1.11

0.11

1.1

2.42

5.67

u/ml

—

LSIL lesion of the cervix uteri

125

1212

1.03

0.11

1.1

4.90

5.31

u/ml

0.14

626

Twin gestation

1005

0.96

0.11

1.1

2.79

5.02

u/ml

1.75

518

Femoral hernia

124

1.13

0.11

1.1

1.0

0.99

5.05

u/ml

—

Spondyloarthritis

138

1340

1.03

0.11

1.0

1.1

6.59

5.73

u/ml

0.16

701

Other and unspecified intracranial injuries

153

1.11

0.11

1.1

12.54

6.79

u/ml

—

Complications of internal orthopaedic prosthetic devices, implants and grafts

700

0.96

0.11

1.0

1.1

5.38

3.72

u/ml

0.28

324

Benign neoplasm: Descending colon

182

1.10

0.11

1.1

3.17

3.67

u/ml

0.07

Measles

1.17

0.11

1.1

1.0

15.09

6.14

u/ml

—

Endometriosis of intestine

167

0.90

0.11

1.0

1.1

8.08

4.80

u/ml

—

Iron deficiency anaemia

255

2475

1.02

0.10

1.1

7.71

4.79

u/ml

1.04

125

1291

Abnormal weight loss

436

1.06

0.10

1.1

3.34

5.85

u/ml

1.12

242

Maternal care for known or suspected fetal abnormality and damage

214

1944

0.98

0.10

1.1

4.71

5.28

u/ml

0.24

120

1026

218

0.92

0.10

1.0

1.1

8.05

6.12

u/ml

—

100

Injury of other and unspecified intrathoracic organs

290

0.93

0.10

1.1

9.42

6.53

u/ml

0.28

153

Primary coxarthrosis, bilateral

751

1.04

0.10

1.1

1.0

3.65

2.76

u/ml

0.14

327

DVT of lower extremities

799

0.96

0.10

1.0

1.1

2.47

3.68

u/ml

0.76

374

Constipation

689

4879

1.01

0.10

1.1

4.12

4.77

u/ml

0.37

332

2547

Chronic lymphocytic leukaemia, helper endpoint

1.14

0.10

1.2

1.0

—

3.59

—

Chronic lymphocytic leukaemia and small lyphocytis leukaemia, excluding all cancers (controls excluding all cancers)

1.14

0.10

1.2

1.0

—

3.59

—

Pregnancy hypertension

453

4138

0.99

0.10

1.1

2.61

4.85

u/ml

6.41

210

2035

Complications of surgical and medical care, not elsewhere classified

873

6199

1.01

0.10

1.1

4.74

5.03

u/ml

0.20

455

3120

Injury of nerves at wrist and hand level

232

1.08

0.09

1.0

1.1

2.09

5.67

u/ml

1.27

120

Foreign body on external eye

113

1098

1.03

0.09

1.0

1.1

6.38

5.66

u/ml

0.15

605

Disorder of the sleep-wake schedule

176

0.91

0.09

1.1

1.56

7.21

u/ml

—

120

Failed induction of labour

747

0.96

0.09

1.1

3.38

5.76

u/ml

0.99

398

Pleural effusion

381

0.94

0.09

1.0

1.1

3.44

3.86

u/ml

0.05

182

Complications of other internal prosthetic devices, implants and grafts

145

0.90

0.09

1.1

4.89

7.30

u/ml

—

Other obstetric trauma

615

1.04

0.09

1.1

4.46

4.83

u/ml

0.09

312

Torticollis

145

1.11

0.09

1.2

1.1

11.05

6.02

u/ml

—

Medical treatment for female infertility

278

2727

1.02

0.09

1.0

1.1

4.25

4.88

u/ml

0.33

132

1394

Inguinal or femoral hernia, bilateral

340

1.06

0.09

1.0

1.1

4.15

5.97

u/ml

0.24

166

Presence of other devices

792

1.03

0.09

1.1

4.15

4.16

u/ml

0.00

378

Primary gonarthrosis, bilateral

195

1671

1.02

0.09

1.0

1.83

2.96

u/ml

1.36

698

Other blood glucose lowering drugs, excl. Insulins

513

0.95

0.09

1.0

1.1

1.61

3.38

u/ml

1.32

248

Lupus erythematosus

1.14

0.09

1.3

1.1

2.84

3.96

u/ml

—

Iridocyclitis

150

1535

0.98

0.09

1.1

8.51

5.78

u/ml

0.69

779

Zoster [herpes zoster]

756

0.97

0.09

1.1

8.55

4.32

u/ml

1.04

373

Benign neoplasm of breast

754

1.04

0.09

1.1

6.21

4.38

u/ml

0.31

365

Golimumab

288

0.94

0.09

1.0

1.1

2.93

6.10

u/ml

1.24

156

Disorders of mineral metabolism

380

1.05

0.09

1.1

1.92

4.60

u/ml

1.64

205

HSIL lesion of the cervix uteri

213

2091

1.02

0.08

1.0

1.1

5.42

4.86

u/ml

0.18

1082

Sodium-glucose co-transporter 2 (SGLT2) inhibitors

143

1397

1.02

0.08

1.0

1.1

2.90

3.89

u/ml

0.75

680

Gonarthrosis

440

2556

0.99

0.08

1.1

3.07

3.88

u/ml

0.82

213

1143

Congenital malformations of the circulatory system

157

1554

0.98

0.08

1.0

1.1

5.91

6.02

u/ml

0.03

964

Phlebitis and thrombophlebitis (not including DVT)

126

1229

1.03

0.08

1.1

2.66

4.36

u/ml

1.49

591

Toxic effect of alcohol

107

1.12

0.08

1.0

1.1

8.50

8.26

u/ml

—

Labour and delivery complicated by fetal stress [distress]

378

2488

1.01

0.08

1.1

5.30

5.62

u/ml

0.17

198

1300

Bacterial sepsis of newborn

185

1.09

0.08

1.2

10.63

7.03

u/ml

0.26

145

Cytomegalovirus infection, IBD co-morbidity

113

0.88

0.08

1.1

1.0

9.82

6.95

u/ml

—

Hypertensive Heart Disease

480

1.04

0.08

1.0

2.25

2.59

u/ml

0.11

222

Haemorrhagic and haematological disorders of fetus and newborn

565

0.96

0.08

1.2

5.88

6.36

u/ml

0.11

423

Benign neoplasm: Pancreas

0.83

0.08

1.0

2.75

3.31

u/ml

—

Emotionally unstable personality disorder

152

1488

1.02

0.08

1.1

4.36

6.37

u/ml

1.12

796

Cerebral aneurysm, nonruptured

381

1.05

0.08

1.1

2.65

3.25

u/ml

0.23

177

Melanocytic naevi of scalp and neck

154

0.91

0.08

1.1

16.80

8.77

u/ml

—

Problems related to lifestyle

906

0.97

0.08

1.1

8.97

6.59

u/ml

0.48

468

Preterm labour and delivery

224

2277

0.98

0.08

1.1

4.94

4.09

u/ml

0.34

102

1100

Pedal cyclist injured in transport accident

196

1925

1.02

0.08

1.1

6.54

6.52

u/ml

0.01

118

1033

Obstructed labour due to malposition and malpresentation of fetus

271

2591

0.98

0.08

1.1

4.76

4.79

u/ml

0.01

138

1291

Hirsutism in women

205

1.08

0.08

1.0

1.1

4.16

4.65

u/ml

0.07

106

Hypoplasia of dental enamel , including avohilmo

644

0.96

0.08

1.2

4.03

6.97

u/ml

0.99

466

Cardiovascular diseases (excluding rheumatic etc)

994

5697

1.01

0.08

1.1

5.77

5.84

u/ml

0.04

531

3126

Bacterial pneumoniae

259

2258

1.02

0.07

1.0

1.1

5.47

5.42

u/ml

0.02

148

1166

Duodenal ulcer

254

1.06

0.07

1.1

3.73

3.70

u/ml

0.00

111

Dentinal caries

188

1837

1.02

0.07

1.1

5.89

6.42

u/ml

0.15

124

1052

Outcome of delivery

260

1635

0.98

0.07

1.1

7.58

5.47

u/ml

1.01

157

857

Benign neoplasm: Adrenal gland

264

1.06

0.07

1.0

1.1

8.23

3.31

u/ml

0.36

123

Hypertrophic disorders of skin

520

1.04

0.07

1.1

9.10

5.42

u/ml

0.50

288

Scar conditions and fibrosis of skin

276

0.94

0.07

1.1

13.81

5.81

u/ml

0.58

144

Arthrosis

598

3256

1.01

0.07

1.1

3.52

4.46

u/ml

0.94

296

1546

Hernia of abdominal wall, postoperative

100

975

1.03

0.07

1.0

1.1

4.21

4.85

u/ml

0.15

459

Psoriasis (vulgaris), strict definition

186

1.08

0.07

1.1

1.28

6.42

u/ml

2.68

Special screening examination for other diseases and disorders

609

1.03

0.07

1.0

1.1

6.91

6.77

u/ml

0.02

322

Other disorders of skin and subcutaneous tissue, not elsewhere classified

698

1.03

0.07

1.0

1.1

1.79

4.52

u/ml

3.06

348

Benign neoplasm: Skin of trunk

235

1.06

0.07

1.2

1.1

11.21

6.43

u/ml

0.33

130

Mental disorders, not otherwise specified

813

0.97

0.07

1.1

3.57

6.31

u/ml

0.95

439

Gestational [pregnancy-induced] hypertension

294

2972

0.99

0.07

1.1

2.60

4.91

u/ml

5.06

131

1524

Total colectomy

245

0.94

0.07

1.1

4.92

6.82

u/ml

0.37

122

Total colectomy operation

245

0.94

0.07

1.1

4.92

6.82

u/ml

0.37

122

Recurrent dislocation and subluxation of joint

671

0.97

0.07

1.1

6.95

6.28

u/ml

0.13

337

Abnormalities of gait and mobility

509

0.96

0.07

1.2

1.1

6.88

5.15

u/ml

0.21

283

Unspecified lump in breast

956

1.03

0.07

1.1

3.34

4.11

u/ml

0.22

456

Infections of genitourinary tract in pregnancy

877

1.03

0.07

1.1

4.19

5.98

u/ml

0.78

476

Intentional self-harm by sharp object

275

0.94

0.07

1.0

1.1

5.18

7.84

u/ml

0.41

161

Dermatophytosis

630

1.03

0.06

1.1

6.33

4.98

u/ml

0.28

338

Family history of certain disabilities and chronic diseases leading to disablement

482

1.04

0.06

1.1

6.61

6.64

u/ml

0.00

264

Traumatic amputation of wrist and hand

173

0.92

0.06

1.1

6.67

5.84

u/ml

—

Hepatic failure, not elsewhere classified

132

0.91

0.06

1.2

1.0

5.68

5.51

u/ml

—

Calculus of lower urinary tract

132

0.91

0.06

1.1

1.0

3.09

5.77

u/ml

—

Pneumococcal septicemia

183

0.93

0.06

1.0

1.1

5.54

8.46

u/ml

0.37

111

Adjustment and management of implanted device

508

0.96

0.06

1.1

5.96

4.44

u/ml

0.22

245

Senile cataract

275

1683

1.01

0.06

1.1

1.0

3.15

2.98

u/ml

0.06

128

730

Other surgical follow-up care

236

1.06

0.06

1.0

1.1

11.80

4.85

u/ml

0.46

130

Paralytic ileus and intestinal obstruction

108

1056

1.02

0.06

1.1

2.75

4.25

u/ml

0.62

519

Benign neoplasm: Skin of trunk

236

1.06

0.06

1.2

1.1

11.21

6.37

u/ml

0.34

123

Sequelae of infectious and parasitic diseases

437

0.96

0.06

1.1

2.89

4.78

u/ml

0.70

211

Accidental poisoning by and exposure to other and unspecified drugs, medicaments and biological substances

609

0.97

0.06

1.1

3.16

6.54

u/ml

1.06

335

Eating disorder

136

1333

1.02

0.06

1.1

5.99

6.73

u/ml

0.18

793

Other specified cerebrovascular diseases, other cerebrovascular disorders in diseases classified elsewhere

162

0.92

0.06

1.2

1.0

1.58

5.84

u/ml

—

Hidradenitis suppurativa

325

0.95

0.06

1.1

10.55

5.30

u/ml

0.53

166

Other renal tubulo-interstitial diseases

162

0.92

0.06

1.1

1.0

2.24

4.96

u/ml

—

Other congenital malformations of limb(s)

119

1.10

0.06

1.1

4.13

5.50

u/ml

—

Cytomegaloviral disease

121

0.91

0.06

1.1

1.0

8.18

7.47

u/ml

—

Other diseases of the digestive system

139

1414

0.98

0.06

1.2

1.1

3.57

5.18

u/ml

0.67

724

Diseases of pulp and periapical tissues, including avohilmo

1207

6301

0.99

0.05

1.1

4.86

6.19

u/ml

2.14

632

3321

Coxarthrosis, primary, with hip surgery

133

1283

0.98

0.05

1.1

1.0

3.44

2.56

u/ml

0.22

557

Other and unspecified disorders of white blood cells

178

1.07

0.05

1.1

2.23

6.07

u/ml

—

411

1.03

0.05

1.0

0.48

1.86

u/ml

2.32

178

Abscess of anal and rectal regions

583

1.03

0.05

1.1

9.67

5.20

u/ml

0.73

317

Oral lichen ruber planus wide, hypothyreosis or thyroxin

188

1.06

0.05

1.1

2.34

2.30

u/ml

—

271

1.05

0.05

1.0

0.96

1.39

u/ml

—

115

Embedded teeth, including avohilmo

123

1252

0.98

0.05

1.0

1.1

7.95

7.06

u/ml

0.20

718

Malignant neoplasm of thyroid gland, excluding all cancers (controls excluding all cancers)

415

1.04

0.05

1.1

3.49

4.68

u/ml

0.46

215

Viral haemorrhagic fevers, not elsewhere classified/unspecified

425

1.04

0.05

1.1

17.62

5.74

u/ml

0.49

205

Subarachnoid haemorrhage

356

1.04

0.05

1.1

2.88

2.93

u/ml

0.01

167

Other viral infections characterized by skin and mucous membrane lesions, not elsewhere classified

564

1.03

0.05

1.2

1.1

6.81

6.13

u/ml

0.09

364

Benign neoplasm: Rectosigmoid junction

100

1.10

0.05

1.0

0.95

4.39

u/ml

—

All pneumoniae

1029

7064

1.01

0.05

1.1

5.77

5.50

u/ml

0.20

611

3681

Aortic valve malfunction, age under 60 years

576

0.97

0.05

1.0

1.1

6.15

4.98

u/ml

0.21

314

Calcific tendinitis of shoulder

297

1.04

0.05

1.0

1.1

2.12

4.38

u/ml

1.25

123

Systemic sclerosis, icd10

110

1.09

0.05

1.0

0.93

2.98

u/ml

—

Systemic sclerosis

110

1.09

0.05

1.0

0.93

3.07

u/ml

—

≡ Risteys

FG R12 + FR

FinnGen R11 + FinRegistry

FinnGen R10 + FinRegistry

FinnGen R10

FinnGen R9

FinnGen R8

FinnGen R7

FinnGen R6

FinnGen R5

FinnGen R4

FinnGen R3

Timothy IgE Ab [Units/volume] in Serum

Coding

Definition

OMOP mapping QC

Cohort

Year of birth distribution

Age at first measurement

Age at last measurement

Age at start of registry

Duration from first to last measurement

Statistics

Number of measurements over the years

Number of measurements per person

Distribution of lab values

Value range per person

LabWAS