laryngeal neoplasm: A benign or malignant neoplasm involving the larynx.
Benign neoplasm: Connective and other soft tissue of trunk, unspecified
DOID EFO Endpoint Browser PheWeb
CD2_BENIGN_CONNSOFT_TRUNK
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
225 |
4. Check minimum number of eventsNone |
225 |
5. Include endpointsNone |
225 |
6. Filter based on genotype QC (FinnGen only) |
221 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- D21
- Name in latin
- Neoplasma benignum textus connectivi trunci
Similar endpoints
↥List of similar endpoints to
Benign neoplasm: Connective and other soft tissue of trunk, unspecified
based on the number of shared cases.
Similar with more cases:
- Other benign neoplasms of connective and other soft tissue
- Benign neoplasms
- Neoplasms
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1719 | 1001 | 710 |
| Only index persons | 1440 | 860 | 580 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.02 | 0.03 | 0.02 |
| Only index persons | 0.03 | 0.03 | 0.02 |
| Median age at first event (years) | |||
| Whole population | 46.16 | 44.72 | 48.09 |
| Only index persons | 43.93 | 42.86 | 45.52 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 221 | 131 | 90 |
| Unadjusted period prevalence (%) | 0.04 | 0.05 | 0.04 |
| Median age at first event (years) | 45.09 | 41.36 | 50.52 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 225
- Matched controls
- 2250
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D21.6
ICD-10 Finland
Benign neoplasm: Connective and other soft tissue of trunk, unspecified
+∞
206.3
165
*
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
15.4
66.2
66
59
21502
ICD-8 Finland
Other benign neoplasm of muscular and connective tissue, Trunci
+∞
56.7
52
*
NAR20
NOMESCO Finland
Complete excision of soft tissue tumour of spine, unspecified
+∞
12.6
12
*
R22.2
ICD-10 Finland
Localized swelling, mass and lump, trunk
7.5
8.8
20
29
ZXD10
NOMESCO Finland
Scheduled procedure
2.2
7.8
101
604
ZXA00
NOMESCO Finland
Right side
2.3
7.5
73
387
N06AX11
ATC
mirtazapine; oral
2.2
7.0
89
524
XW3AT
NOMESCO Finland
Biopsy of other superficial organ with ultrasound guidance
71.8
6.5
7
*
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
50
290
1.93
3.80
4.3
3.1
0.78
0.82
mmol/l
1.29
45
269
30
145
2.23
3.68
3.5
2.9
76.00
62.82
ml/min/173m2
1.32
12
60
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
13
42
3.22
3.43
1.8
2.2
0.41
0.34
u/ml
—
5
21
34
183
2.01
3.18
4.4
4.7
21.50
31.85
ug/l
0.15
25
152
83
596
1.62
2.95
6.1
3.2
2.36
2.35
mmol/l
0.21
72
531
51
325
1.74
2.83
1.7
1.7
1084.79
1232.40
nmol/l
0.53
41
243
38
225
1.83
2.69
4.9
4.7
1.02
1.00
mmol/l
0.25
32
200
108
840
1.55
2.66
9.7
12.3
1.21
1.23
inr
0.08
31
245
19
90
2.21
2.47
11.3
5.2
25.72
24.46
mmol/l
0.80
19
90
62
432
1.60
2.43
3.1
2.1
—
—
—
0
0
46
302
1.66
2.28
2.9
2.8
2.19
2.73
e6/l
0.25
25
167
7
18
3.98
2.27
1.0
1.2
—
—
—
0
0
142
1198
1.50
2.24
5.4
4.6
2.83
212.35
e6/l
—
6
20
6
14
4.37
2.16
1.0
1.1
592.83
242.29
pmol/l
—
6
14
6
14
4.37
2.16
1.2
1.9
11.17
12.56
umol/l
—
6
14
120
993
1.45
2.00
8.3
5.7
9.95
11.23
umol/l
1.05
113
936
5
11
4.62
1.95
1.0
1.8
—
—
—
0
0
32
199
1.71
1.94
1.6
1.8
—
—
—
0
0
47
327
1.55
1.83
4.9
3.0
2.41
2.45
mmol/l
1.77
42
288
42
285
1.58
1.82
1.6
1.8
—
—
—
0
0
31
196
1.67
1.77
1.5
1.7
—
—
—
0
0
48
339
1.53
1.75
2.8
3.7
59.21
222.77
ng/l
0.90
29
252
45
315
1.54
1.71
2.8
2.7
0.56
1.02
e6/l
1.24
26
179
68
520
1.44
1.68
3.6
3.1
0.28
0.38
e6/l
0.45
55
397
198
1840
1.63
1.60
19.9
13.7
24.78
22.68
mg/l
0.38
169
1448
10
44
2.33
1.58
1.2
1.2
—
—
—
0
0
25
155
1.69
1.55
12.0
6.2
1.19
1.54
mmol/l
1.67
25
149
11
51
2.22
1.53
1.3
1.2
—
—
—
0
0
159
1423
1.40
1.49
10.3
7.1
75.35
75.58
u/l
0.02
147
1330
97
804
1.36
1.47
8.6
5.2
1.20
1.22
mmol/l
1.87
86
721
104
879
1.34
1.36
10.8
6.0
1.19
1.22
mmol/l
2.54
87
750
29
194
1.57
1.35
11.8
6.7
14.22
12.07
kpa
1.17
29
181
29
194
1.57
1.35
11.9
6.7
5.47
5.20
kpa
0.61
29
180
123
1067
1.34
1.35
6.7
4.5
6.41
6.67
mmol/l
1.05
117
988
123
1070
1.33
1.31
14.2
9.2
4.14
4.13
e9/l
0.02
113
938
141
1252
1.34
1.30
3.2
2.9
55.30
43.19
u/l
0.58
130
1174
10
48
2.13
1.29
1.5
2.8
1.44
1.59
mg/l
—
10
41
9
44
2.09
1.28
1.3
1.4
—
—
—
0
0
55
424
1.39
1.28
1.9
1.8
0.75
1.13
mg/l
1.69
46
316
80
660
1.33
1.21
3.6
3.1
—
—
—
0
0
10
184
0.52
1.20
5.8
3.2
—
—
—
0
0
8
38
2.15
1.19
1.5
1.4
—
—
—
0
0
8
38
2.15
1.19
1.5
1.4
—
—
—
0
0
6
26
2.34
1.19
1.0
1.4
—
—
—
0
0
72
587
1.33
1.18
2.1
2.3
53.97
55.04
u/l
0.12
67
541
0
34
0.00
1.17
0.0
1.7
—
—
—
0
0
5
20
2.53
1.15
1.0
1.2
—
—
—
0
0
5
21
2.41
1.09
1.0
1.9
—
—
—
0
0
28
197
1.48
1.06
12.2
6.7
0.72
1.34
mmol/l
0.39
21
155
5
22
2.30
1.04
1.2
1.9
—
—
—
0
0
7
34
2.09
1.04
2.3
1.6
—
—
—
0
0
16
99
1.66
1.03
3.8
3.3
1.54
1.55
mmol/l
0.00
11
74
0
31
0.00
0.97
0.0
1.7
—
—
—
0
0
6
28
2.17
0.92
4.0
3.9
52.67
57.11
%
—
6
28
84
725
1.25
0.86
2.3
2.0
93.76
96.79
pmol/l
0.20
48
369
8
46
1.77
0.83
1.1
1.3
—
—
—
0
0
6
32
1.90
0.82
1.0
1.5
—
—
—
0
0
0
26
0.00
0.79
0.0
1.7
—
—
—
0
0
0
26
0.00
0.79
0.0
1.7
—
—
—
0
0
0
27
0.00
0.78
0.0
1.0
—
3.67
—
0
16
15
99
1.55
0.78
1.4
1.6
—
—
—
0
0
36
282
1.33
0.77
2.9
2.2
13.08
13.42
umol/l
0.10
36
257
5
24
2.11
0.75
1.2
1.3
—
101.40
—
0
5
129
1179
1.22
0.75
3.0
3.2
—
—
—
0
0
97
864
1.22
0.72
3.4
2.4
—
—
—
0
0
12
77
1.59
0.70
1.3
1.3
14.29
30.30
iu/l
1.94
12
66
7
42
1.69
0.69
1.0
1.3
—
43.30
—
0
5
159
1680
0.82
0.66
5.4
5.5
38.86
39.59
mmol/mol
0.45
143
1569
5
29
1.74
0.64
1.4
2.2
—
—
—
0
0
6
101
0.58
0.64
1.0
1.2
—
—
—
0
0
8
49
1.66
0.63
1.3
1.1
—
—
—
0
0
8
52
1.56
0.60
1.5
1.6
—
—
—
0
0
84
750
1.19
0.59
2.8
2.3
76.49
75.44
nmol/l
0.15
75
659
145
1358
1.19
0.58
4.8
4.0
9.94
10.97
mm/h
0.45
139
1238
11
160
0.67
0.58
2.2
1.7
—
—
—
0
0
47
402
1.21
0.52
4.7
4.2
18.62
21.25
%
0.73
25
188
10
67
1.52
0.50
1.6
2.1
9.37
10.06
g/l
—
10
61
10
67
1.52
0.50
1.4
1.8
1.67
1.65
g/l
—
10
54
7
45
1.57
0.49
1.0
1.6
—
—
—
0
0
7
47
1.50
0.48
1.0
1.6
—
—
—
0
0
10
68
1.49
0.48
1.6
2.1
3.12
2.94
g/l
—
10
63
90
823
1.16
0.46
3.2
2.6
147.01
110.47
ug/l
0.58
84
759
50
436
1.19
0.46
1.7
1.5
22.03
20.86
nmol/l
0.17
40
361
181
1744
1.19
0.45
18.6
12.9
84.50
82.62
ml/min/173m2
0.50
142
1437
7
51
1.38
0.44
3.0
1.5
—
—
—
0
0
5
32
1.57
0.42
1.0
1.1
—
—
—
0
0
8
59
1.37
0.41
1.1
2.2
35.32
38.13
g/l
—
8
54
7
103
0.67
0.40
2.1
1.8
—
—
—
0
0
163
1693
0.86
0.40
5.7
4.7
1.72
1.90
mu/l
1.62
152
1544
20
161
1.27
0.38
1.8
2.0
387.95
375.74
nmol/l
0.11
20
145
8
111
0.71
0.38
3.5
6.6
24.82
24.99
mmol/l
—
8
101
9
70
1.30
0.37
1.6
1.9
—
—
—
0
0
9
124
0.71
0.36
2.2
2.2
13.99
13.20
nmol/l
—
9
118
6
43
1.41
0.35
1.5
1.4
—
—
—
0
0
10
73
1.39
0.35
1.6
2.1
—
—
—
0
0
10
73
1.39
0.35
1.6
2.1
7.00
7.40
g/l
—
10
68
10
73
1.39
0.35
1.6
2.1
3.67
3.49
g/l
—
10
68
25
210
1.21
0.34
3.9
4.3
32.50
32.26
%
0.03
14
144
6
45
1.34
0.34
2.8
2.4
22.55
24.25
mmol/l
—
6
45
170
1753
0.88
0.33
4.4
4.4
5.92
5.92
mmol/l
0.00
156
1603
44
490
0.87
0.31
1.8
1.7
1.42
1.41
mmol/l
0.05
38
415
198
1940
1.17
0.28
23.0
15.8
76.19
76.19
umol/l
0.00
198
1940
15
122
1.25
0.27
1.4
1.3
152.46
176.03
iu/ml
—
5
43
19
160
1.20
0.26
16.3
7.6
118.37
120.95
g/l
0.22
19
154
96
910
1.10
0.25
4.1
3.8
0.00
0.00
estimate
-0.00
14
170
206
2029
1.18
0.23
30.1
20.2
40.13
40.24
%
0.11
198
1920
5
38
1.32
0.23
1.4
1.3
—
—
—
0
0
27
304
0.87
0.23
3.3
3.0
0.80
0.80
ug/l
0.01
20
197
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
2.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.5
—
—
—
0
0
0
13
0.00
0.21
0.0
3.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
558.83
—
0
6
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
36.33
—
0
6
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
6
53
1.14
0.19
1.3
1.4
—
—
—
0
0
94
900
1.08
0.18
5.3
5.1
0.00
0.00
estimate
-0.00
14
175
68
718
0.92
0.18
4.0
3.9
—
—
—
0
0
144
1403
1.07
0.17
4.5
3.9
14.85
14.76
pmol/l
0.13
132
1268
47
500
0.92
0.15
4.2
4.1
0.00
0.00
estimate
-0.00
13
171
47
445
1.07
0.12
3.4
1.9
3.40
3.11
mg/l
0.24
41
384
31
289
1.08
0.11
1.1
1.3
1.17
9.19
u/ml
2.20
16
119
179
1813
0.94
0.11
4.8
4.8
2.70
2.76
mmol/l
0.41
163
1673
22
202
1.10
0.11
7.3
8.0
—
—
—
0
0
14
125
1.13
0.10
1.4
1.5
—
—
—
0
0
14
155
0.90
0.09
14.1
3.6
1.22
1.23
mmol/l
0.15
14
132
5
65
0.76
0.08
3.2
2.1
—
—
—
0
0
51
528
0.96
0.07
3.2
3.7
4.09
9.36
mg/mmol
1.78
31
326
92
901
1.04
0.06
3.8
3.8
0.00
0.01
estimate
0.50
16
187
9
103
0.87
0.06
1.0
1.0
—
—
—
0
0
40
415
0.96
0.06
1.4
1.2
3.06
1.11
u/ml
—
5
120
22
232
0.94
0.05
1.9
2.0
—
—
—
0
0
20
211
0.94
0.04
1.9
1.8
—
—
—
0
0
52
533
0.97
0.04
3.2
3.1
1131.26
997.49
ng/l
0.19
45
445
31
299
1.04
0.04
1.3
1.4
—
—
—
0
0
33
319
1.04
0.04
1.4
1.5
—
—
—
0
0
36
351
1.03
0.02
1.5
1.8
398.14
434.93
pmol/l
0.48
29
289
14
133
1.06
0.01
2.1
1.9
—
—
—
0
0
178
1786
0.98
0.00
4.4
4.3
4.63
4.65
mmol/l
0.10
164
1657
177
1776
0.98
0.00
4.4
4.2
1.49
1.47
mmol/l
0.31
162
1635
171
1714
0.99
0.00
3.9
3.8
1.32
1.28
mmol/l
0.31
154
1565
69
687
1.01
0.00
3.8
3.8
48.75
44.76
ng/l
0.09
42
476
11
115
0.95
0.00
1.5
1.3
—
—
—
0
0
31
308
1.01
0.00
1.2
1.3
15.90
25.90
iu/ml
—
8
103
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.3
—
—
—
0
0
7
70
1.00
-0.00
1.7
1.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
30.00
—
0
5
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
9
92
0.98
-0.00
1.1
1.5
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
6.63
—
0
6
0
9
0.00
-0.00
0.0
2.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
5
57
0.87
-0.00
1.2
1.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
7
72
0.97
-0.00
2.9
1.9
1.88
4.90
ug/l
—
7
62
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
8
80
1.00
-0.00
5.6
4.0
36.80
48.74
%
—
8
80
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
6
61
0.98
-0.00
2.0
1.4
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint CD2_BENIGN_CONNSOFT_TRUNK and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_CONNSOFT_TRUNK | 1.499 [1.13, 1.98] | 0.005 |
| Birth year | 0.997 [0.99, 1.01] | 0.441 |
During the follow-up period (1.1.1998 — 31.12.2019), 78 out of 505 females with CD2_BENIGN_CONNSOFT_TRUNK died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_CONNSOFT_TRUNK | 1.209 [0.9, 1.63] | 0.211 |
| Birth year | 0.987 [0.98, 1.0] | 0.007 |
During the follow-up period (1.1.1998 — 31.12.2019), 74 out of 385 males with CD2_BENIGN_CONNSOFT_TRUNK died.
Mortality risk
Mortality risk for people of age
years, who have CD2_BENIGN_CONNSOFT_TRUNK.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.139% | 0.242% |
| 5 | 0.901% | 1.482% |
| 10 | 2.238% | 3.51% |
| 15 | 4.364% | 6.891% |
| 20 | 7.564% | 11.619% |
Relationships between endpoints
↥Index endpoint: CD2_BENIGN_CONNSOFT_TRUNK – Benign neoplasm: Connective and other soft tissue of trunk, unspecified
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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