laryngeal neoplasm: A benign or malignant neoplasm involving the larynx.
Benign neoplasm: Connective and other soft tissue of trunk, unspecified
DOID EFO Endpoint Browser PheWeb
CD2_BENIGN_CONNSOFT_TRUNK
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
220 |
4. Check minimum number of eventsNone |
220 |
5. Include endpointsNone |
220 |
6. Filter based on genotype QC (FinnGen only) |
220 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- D21
- Name in latin
- Neoplasma benignum textus connectivi trunci
Similar endpoints
↥List of similar endpoints to
Benign neoplasm: Connective and other soft tissue of trunk, unspecified
based on the number of shared cases.
Similar with more cases:
- Benign neoplasm: Connective and other soft tissue of trunk, unspecified
- Other benign neoplasms of connective and other soft tissue
- Other benign neoplasms of connective and other soft tissue
- Benign neoplasms
- Benign neoplasms
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1719 | 1001 | 710 |
| Only index persons | 1440 | 860 | 580 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.02 | 0.03 | 0.02 |
| Only index persons | 0.03 | 0.03 | 0.02 |
| Median age at first event (years) | |||
| Whole population | 46.16 | 44.72 | 48.09 |
| Only index persons | 43.93 | 42.86 | 45.52 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 220 | 130 | 90 |
| Unadjusted period prevalence (%) | 0.04 | 0.04 | 0.04 |
| Median age at first event (years) | 44.81 | 41.04 | 50.26 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 197
- Matched controls
- 1969
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D21.6
ICD-10 Finland
Benign neoplasm: Connective and other soft tissue of trunk, unspecified
+∞
176.7
142
*
21502
ICD-8 Finland
Other benign neoplasm of muscular and connective tissue, Trunci
+∞
52.5
48
*
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
11.8
29.8
58
67
NAR20
NOMESCO Finland
Complete excision of soft tissue tumour of spine, unspecified
104.9
9.5
10
*
R22.2
ICD-10 Finland
Localized swelling, mass and lump, trunk
7.8
8.2
18
25
ZXA00
NOMESCO Finland
Right side
2.3
6.2
64
335
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
49
278
1.98
3.99
4.3
3.2
0.8
0.8
mmol/l
1.26
44
258
30
143
2.27
3.80
3.6
3.0
76.0
62.8
ml/min/173m2
1.32
12
60
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
13
42
3.23
3.43
1.8
2.2
0.4
0.3
u/ml
—
5
21
83
580
1.69
3.37
6.1
3.2
2.4
2.4
mmol/l
0.42
71
512
33
174
2.05
3.27
4.5
4.7
22.3
30.9
ug/l
0.11
24
146
20
85
2.49
3.26
15.8
7.9
24.4
24.6
mmol/l
0.15
20
78
51
317
1.79
3.10
1.7
1.7
1084.8
1233.5
nmol/l
0.53
41
238
38
218
1.90
2.97
4.9
4.8
1.0
1.0
mmol/l
0.19
32
193
19
84
2.38
2.86
11.3
5.3
25.7
24.5
mmol/l
0.74
19
84
61
420
1.63
2.53
3.1
2.1
—
—
—
0
0
45
289
1.70
2.43
3.0
2.8
2.2
2.8
e6/l
0.24
24
160
7
18
3.98
2.27
1.0
1.2
—
—
—
0
0
6
14
4.37
2.16
1.2
1.9
11.2
12.6
umol/l
—
6
14
32
196
1.74
2.04
1.6
1.8
—
—
—
0
0
47
320
1.60
2.02
4.9
3.0
2.4
2.4
mmol/l
1.54
42
282
137
1164
1.47
2.01
5.5
4.6
2.8
223.1
e6/l
—
6
19
42
279
1.62
1.99
1.6
1.8
—
—
—
0
0
67
501
1.49
1.88
3.7
3.1
0.3
0.4
e6/l
0.39
51
383
31
193
1.71
1.87
1.5
1.7
—
—
—
0
0
116
964
1.43
1.86
8.4
5.7
9.5
11.2
umol/l
2.00
109
908
47
328
1.55
1.81
2.9
3.7
61.2
231.6
ng/l
0.91
28
242
10
41
2.51
1.78
1.2
1.2
—
—
—
0
0
44
304
1.56
1.77
2.9
2.7
0.6
1.0
e6/l
1.10
25
174
96
778
1.42
1.74
8.7
5.1
1.2
1.2
mmol/l
1.76
85
694
122
1036
1.40
1.67
6.7
4.3
6.4
6.7
mmol/l
1.01
116
956
103
850
1.40
1.66
10.8
5.9
1.2
1.2
mmol/l
2.38
86
719
55
408
1.46
1.59
1.9
1.8
0.7
1.1
mg/l
1.43
46
303
193
1795
1.61
1.53
20.2
13.6
25.2
22.3
mg/l
0.55
165
1413
29
188
1.62
1.52
11.8
6.1
14.2
12.0
kpa
1.24
29
176
29
188
1.62
1.52
11.9
6.2
5.5
5.2
kpa
0.61
29
175
79
637
1.37
1.42
3.6
3.2
—
—
—
0
0
120
1042
1.33
1.30
14.5
9.2
4.2
4.1
e9/l
0.11
110
913
154
1388
1.37
1.30
10.5
7.0
75.4
75.1
u/l
0.02
142
1296
9
44
2.09
1.28
1.3
1.4
—
—
—
0
0
28
190
1.54
1.24
12.2
6.2
0.7
1.4
mmol/l
0.42
21
149
137
1221
1.32
1.20
3.3
2.9
55.0
42.6
u/l
0.57
126
1146
8
38
2.15
1.19
1.5
1.4
—
—
—
0
0
8
38
2.15
1.19
1.5
1.4
—
—
—
0
0
6
26
2.34
1.19
1.0
1.4
—
—
—
0
0
70
569
1.34
1.17
2.0
2.2
54.9
55.2
u/l
0.03
65
524
0
34
0.00
1.17
0.0
1.7
—
—
—
0
0
16
96
1.72
1.13
3.8
3.3
1.5
1.6
mmol/l
0.02
11
72
10
51
2.01
1.13
1.2
1.2
—
—
—
0
0
10
179
0.54
1.11
5.8
3.2
—
—
—
0
0
5
21
2.41
1.09
1.0
1.9
—
—
—
0
0
7
33
2.16
1.06
2.3
1.6
—
—
—
0
0
5
22
2.30
1.04
1.2
1.9
—
—
—
0
0
0
31
0.00
0.97
0.0
1.7
—
—
—
0
0
82
705
1.26
0.88
2.3
2.0
95.1
97.3
pmol/l
0.14
47
357
15
96
1.60
0.87
1.4
1.6
—
—
—
0
0
8
45
1.81
0.85
1.1
1.3
—
—
—
0
0
6
32
1.90
0.82
1.0
1.5
—
—
—
0
0
35
272
1.34
0.79
2.9
2.3
13.1
13.7
umol/l
0.18
35
246
0
26
0.00
0.79
0.0
1.7
—
—
—
0
0
0
26
0.00
0.79
0.0
1.7
—
—
—
0
0
0
27
0.00
0.78
0.0
1.0
—
1.9
—
0
10
127
1158
1.23
0.77
3.0
3.2
—
—
—
0
0
154
1637
0.80
0.74
5.5
5.6
39.0
39.6
mmol/mol
0.32
138
1532
171
1616
1.26
0.71
23.0
14.0
39.1
40.2
%
0.93
136
1194
12
77
1.59
0.70
1.3
1.3
14.3
30.3
iu/l
1.94
12
66
5
29
1.74
0.64
1.4
2.2
—
—
—
0
0
8
49
1.66
0.63
1.3
1.1
—
—
—
0
0
8
50
1.62
0.62
1.5
1.6
—
—
—
0
0
82
731
1.19
0.59
2.8
2.3
76.5
75.2
nmol/l
0.18
73
646
93
840
1.19
0.58
5.2
3.9
—
—
—
0
0
141
1321
1.19
0.56
4.8
4.0
10.0
10.9
mm/h
0.38
135
1207
8
122
0.64
0.56
2.4
2.2
15.7
13.4
nmol/l
—
8
116
89
803
1.18
0.56
3.2
2.6
146.4
107.5
ug/l
0.62
83
742
11
158
0.68
0.55
2.2
1.7
—
—
—
0
0
177
1696
1.22
0.53
18.8
12.8
84.3
82.7
ml/min/173m2
0.39
138
1392
6
100
0.59
0.53
1.0
1.2
—
—
—
0
0
49
421
1.21
0.52
1.7
1.5
21.9
21.0
nmol/l
0.13
39
348
29
235
1.27
0.51
12.2
21.2
1.3
1.2
inr
—
8
29
7
45
1.57
0.49
1.0
1.6
—
—
—
0
0
7
47
1.51
0.48
1.0
1.6
—
—
—
0
0
7
51
1.38
0.44
3.0
1.5
—
—
—
0
0
20
158
1.29
0.43
1.8
1.9
387.9
377.0
nmol/l
0.10
20
142
5
31
1.63
0.43
1.0
1.1
—
—
—
0
0
45
392
1.19
0.42
4.8
4.2
18.7
21.4
%
0.73
24
183
7
103
0.67
0.40
2.1
1.8
—
—
—
0
0
165
1709
0.86
0.39
4.4
4.4
5.9
5.9
mmol/l
0.07
151
1564
159
1651
0.87
0.39
5.8
4.7
1.7
1.9
mu/l
1.55
148
1506
9
68
1.34
0.38
1.6
1.9
—
—
—
0
0
9
70
1.30
0.37
1.7
2.1
—
—
—
0
0
6
41
1.48
0.36
1.0
1.3
—
43.3
—
0
5
19
155
1.25
0.33
16.3
6.9
118.4
121.4
g/l
0.26
19
148
24
203
1.20
0.31
3.8
4.3
32.4
32.0
%
0.05
13
136
94
883
1.11
0.30
4.1
3.9
0.0
0.0
estimate
0.00
14
166
7
56
1.26
0.29
1.1
2.3
34.7
37.8
g/l
—
7
49
8
108
0.73
0.29
3.5
6.5
24.8
25.0
mmol/l
—
8
98
193
1893
1.16
0.25
23.2
15.7
76.5
76.2
umol/l
0.04
193
1893
92
873
1.09
0.23
5.4
5.1
0.0
0.0
estimate
0.00
14
169
26
294
0.87
0.23
3.3
3.0
0.8
0.8
ug/l
0.05
19
190
5
41
1.22
0.22
1.6
1.4
—
—
—
0
0
0
11
0.00
0.21
0.0
2.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.5
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
558.8
—
0
6
0
13
0.00
0.21
0.0
3.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
36.3
—
0
6
141
1369
1.08
0.20
4.5
4.0
14.9
14.8
pmol/l
0.15
129
1240
6
53
1.14
0.19
1.3
1.4
—
—
—
0
0
44
474
0.91
0.18
1.8
1.7
1.4
1.4
mmol/l
0.04
38
401
14
120
1.18
0.17
1.4
1.5
—
—
—
0
0
14
120
1.18
0.17
1.4
1.3
152.5
163.9
iu/ml
—
5
41
22
198
1.12
0.15
7.3
8.1
—
—
—
0
0
46
432
1.08
0.14
3.4
1.9
3.4
3.1
mg/l
0.24
41
374
174
1768
0.92
0.14
4.8
4.8
2.7
2.8
mmol/l
0.46
158
1631
90
871
1.06
0.12
3.8
3.8
0.0
0.0
estimate
0.00
12
171
21
230
0.90
0.12
1.9
2.0
—
—
—
0
0
67
697
0.94
0.12
4.0
4.0
—
—
—
0
0
19
209
0.90
0.12
2.0
1.8
—
—
—
0
0
69
668
1.05
0.09
3.8
3.8
48.8
44.0
ng/l
0.11
42
456
36
342
1.06
0.08
1.5
1.8
398.1
438.1
pmol/l
0.54
29
283
5
65
0.76
0.08
3.2
2.1
—
—
—
0
0
47
489
0.95
0.08
4.2
4.2
0.0
0.0
estimate
0.00
13
165
7
68
1.03
0.08
1.7
1.7
—
—
—
0
0
8
76
1.05
0.07
5.6
3.8
36.8
50.3
%
—
8
76
30
285
1.06
0.07
1.1
1.3
1.2
9.2
u/ml
2.20
16
119
33
315
1.06
0.06
1.4
1.5
—
—
—
0
0
9
100
0.90
0.06
1.0
1.0
—
—
—
0
0
39
405
0.95
0.06
1.4
1.3
3.1
1.1
u/ml
—
5
117
173
1741
0.97
0.03
4.4
4.3
4.6
4.6
mmol/l
0.17
159
1615
30
291
1.04
0.02
1.3
1.3
—
—
—
0
0
14
148
0.94
0.02
14.1
3.7
1.2
1.2
mmol/l
0.08
14
126
14
133
1.06
0.01
2.1
1.9
—
—
—
0
0
52
516
1.01
0.00
3.2
3.2
1131.3
1010.0
ng/l
0.17
45
430
167
1671
1.00
0.00
3.9
3.8
1.3
1.3
mmol/l
0.41
150
1526
173
1731
1.00
0.00
4.4
4.2
1.5
1.5
mmol/l
0.24
158
1593
11
113
0.97
0.00
1.5
1.3
—
—
—
0
0
30
303
0.99
0.00
1.2
1.3
15.9
26.3
iu/ml
—
8
101
0
8
0.00
0.00
0.0
1.5
—
—
—
0
0
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
9
93
0.97
0.00
1.1
1.5
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
6.6
—
0
6
0
9
0.00
0.00
0.0
2.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
30.0
—
0
5
0
9
0.00
0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
6
61
0.98
0.00
2.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
5
57
0.87
0.00
1.2
1.6
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint CD2_BENIGN_CONNSOFT_TRUNK and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_CONNSOFT_TRUNK | 1.499 [1.13, 1.98] | 0.005 |
| Birth year | 0.997 [0.99, 1.01] | 0.441 |
During the follow-up period (1.1.1998 — 31.12.2019), 78 out of 505 females with CD2_BENIGN_CONNSOFT_TRUNK died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_CONNSOFT_TRUNK | 1.209 [0.9, 1.63] | 0.211 |
| Birth year | 0.987 [0.98, 1.0] | 0.007 |
During the follow-up period (1.1.1998 — 31.12.2019), 74 out of 385 males with CD2_BENIGN_CONNSOFT_TRUNK died.
Mortality risk
Mortality risk for people of age
years, who have CD2_BENIGN_CONNSOFT_TRUNK.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.139% | 0.242% |
| 5 | 0.901% | 1.482% |
| 10 | 2.238% | 3.51% |
| 15 | 4.364% | 6.891% |
| 20 | 7.564% | 11.619% |
Relationships between endpoints
↥Index endpoint: CD2_BENIGN_CONNSOFT_TRUNK – Benign neoplasm: Connective and other soft tissue of trunk, unspecified
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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