Risteys ·

OMOP concept ID	Test name	Measurement unit (harmonized unit)	N people	N records	Missing measurement value	Harmonized value distribution	Test outcome NA N A AA L LL H HH
40768441	lr-pad	— (—)	2985	4140	100.00%	Distribution not available

LabWAS

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

ILD medications: azathioprine

330

287

12.02

322.61

1.7

1.1

—

Azathioprine

330

306

11.27

309.15

1.7

1.5

—

Hepatocellular carcinoma, excluding all cancers (controls excluding all cancers)

227

155.09

307.65

1.9

1.4

—

Any gastric operation

807

317

12.93

307.65

1.5

1.0

—

Cirrhosis, broad definition used in the article https://doi.org/10.1101/594523

516

285

19.81

307.65

2.2

1.2

—

First line medication for Crohn's disease

1126

1416

4.39

307.65

1.6

1.2

—

Cirrhosis of liver, NAS

290

39.76

307.65

2.2

1.3

—

Malignant neoplasm of liver and intrahepatic bile ducts

235

54.27

307.65

1.8

1.3

—

Chronic hepatitis, not elsewhere classified

327

102.46

307.65

1.8

1.1

—

Cholangitis (primary sclerosing, PSC)

312

110

32.49

307.65

2.2

1.3

—

Diseases of liver

1377

530

28.39

307.65

1.6

1.1

—

Secondary malignant neoplasm of other and unspecified sites, excluding all cancers (controls excluding all cancers)

373

313

12.37

307.65

1.1

1.3

—

Other diseases of liver

679

260

28.60

307.65

1.5

1.1

—

Malignant neoplasm of digestive organs

635

663

9.75

307.65

1.3

1.2

—

ILD medications: immunosuppressive drugs

822

1433

5.61

307.65

2.0

1.1

—

L04AD Calcineurin inhibitors

372

249

16.27

307.65

3.1

1.2

—

Malignant neoplasm of digestive organs, excluding all cancers (controls excluding all cancers)

818

512

12.92

307.65

1.4

—

Secondary uncertain malignant neoplasm, excluding all cancers (controls excluding all cancers)

743

563

12.01

307.65

1.1

1.4

—

Fibrosis and cirrhosis of liver

497

65.08

307.65

2.0

1.1

—

Secondary malignant neoplasm of respiratory and digestive organs, excluding all cancers (controls excluding all cancers)

490

232

22.61

307.65

1.1

1.3

—

Other inflammatory liver diseases

334

46.71

307.65

1.6

1.1

—

Malignant neoplasm of intrahepatic ducts, biliary tract and gallbladder, excluding all cancers (controls excluding all cancers)

408

87.77

307.65

1.7

1.3

—

Nonalcoholic fatty liver disease

336

207

17.78

307.65

1.4

—

Malignant neoplasm of intrahepatic ducts, biliary tract and gallbladder

277

47.86

307.65

1.7

1.3

—

Primary biliary cholangitis (PBC)

204

62.13

307.65

1.7

1.1

—

Transplanted organ and tissue status

360

212

18.62

307.65

3.2

1.2

—

Oesophageal varices

235

36.20

307.65

2.6

1.3

—

GASTRO-related operations

807

317

12.93

307.65

1.5

1.0

—

Cholangitis (primary sclerosing, PSC), with reimbursement 202

190

91.27

307.65

2.3

1.1

—

Other medical care

537

875

6.13

303.45

1.2

1.3

—

Hepatocellular carcinoma

161

65.18

287.08

1.9

1.1

—

Oxycodone

463

691

6.63

281.55

1.3

—

Autoimmune hepatitis

140

148.51

274.32

1.5

1.1

—

Hepatic failure, not elsewhere classified

164

41.57

268.04

2.3

1.1

—

Colitis, primary sclerosing

143

79.34

262.67

2.3

1.0

—

Alcoholic liver disease

218

140

16.45

254.84

2.2

1.2

—

ILD medications

1047

1624

3.57

254.32

1.8

1.1

—

L04AA Selective immunosuppressants

379

559

7.02

244.63

2.6

1.2

—

ILD medications: prednisolone, methylprednisolone, prednisone

999

1600

3.56

244.39

1.8

1.1

—

Other diseases of biliary tract

216

151

15.22

241.50

2.4

1.2

—

Disorders of gallbladder, biliary tract and pancreas

941

1733

3.54

238.92

1.6

1.3

—

Ascites

200

124

17.30

238.61

2.2

1.2

—

Reimbursement for rheumatic diseases

642

1551

4.20

236.44

1.6

1.3

—

Budesonide

265

275

10.03

229.22

1.8

1.4

—

Malignant neoplasm, wide definition for exclusion

778

1204

3.86

215.83

1.4

1.5

—

Malignant neoplasm, wide definition for exclusion, excluding all cancers (controls excluding all cancers)

778

1204

3.86

215.82

1.4

1.5

—

Malignant neoplasm, excluding all cancers (controls excluding all cancers)

778

1205

3.86

215.61

1.4

1.5

—

IBD (strict) with PSC

113

96.30

213.41

2.4

1.0

—

Inflammatory bowel disease treatment related agents

1011

1806

3.21

212.70

1.5

1.3

—

Anaemias

305

208

9.94

212.53

1.8

1.3

—

Malignant neoplasm of pancreas, excluding all cancers (controls excluding all cancers)

158

20.21

204.50

1.0

1.4

—

Colitis, primary sclerosing, strict definition

111

77.26

202.70

2.3

1.0

—

Malignant neoplasm

771

1293

3.57

193.02

1.3

1.5

—

Dialysis, with operation codes

235

269

9.11

188.84

3.2

1.3

—

Gastrointestinal diseases

448

378

5.99

184.34

1.5

1.1

—

Nephropathy related operations

227

273

8.67

175.42

3.2

1.3

—

Ulcerative colitis (strict) with PSC

93.69

171.04

2.3

1.0

—

Autoimmune diseases excluding thyroid diseases, strict definition

859

1562

3.09

169.40

1.5

1.4

—

Autoimmune diseases excluding thyroid diseases

870

1604

3.04

166.47

1.5

1.3

—

Abnormal findings on examination of blood, without diagnosis

486

1149

4.02

166.09

1.4

1.3

—

Any reimbursement code in KELA

437

420

5.26

159.86

1.5

1.1

—

Unspecified jaundice

128

18.65

158.91

1.9

1.2

—

5-aminosalicylic acid

270

439

6.28

158.28

1.8

1.4

—

Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism

810

2003

2.92

157.77

1.5

1.3

—

Abnormal serum enzyme levels

355

734

4.88

157.09

1.3

—

Other bacterial diseases

788

1846

2.98

156.75

1.6

1.3

—

Bacterial infection, other or unspecified

475

1109

3.91

155.15

1.6

1.2

—

Any event in cancer register

734

1387

3.17

153.82

1.4

1.5

—

IBD patients in KELA-register

302

568

5.44

151.96

1.7

1.4

—

Second line medication for Crohn's disease

545

1607

3.44

151.03

1.5

1.4

—

Chronic hepatitis NAS

39.67

147.67

1.7

1.3

—

Inflammatory bowel disease

366

832

4.48

146.91

1.7

1.4

—

Inflammatory bowel disease, strict (require KELA)

302

591

5.22

145.36

1.7

1.4

—

Fever of other and unknown origin

501

1343

3.50

140.28

1.7

1.2

—

Tramadol

633

1280

3.21

139.19

1.7

1.3

—

Hernia of abdominal wall, postoperative

132

103

13.00

137.47

1.8

1.0

—

Mucosal proctocolitis

203

285

7.35

137.19

1.8

1.5

—

Ulcerative colitis

299

611

4.99

136.86

1.8

1.4

—

Oral corticosteroids

801

1755

2.78

136.04

1.4

1.3

—

Neoplasms

570

870

3.54

135.96

1.6

1.4

—

Colorectal cancer, excluding all cancers (controls excluding all cancers)

224

344

6.40

132.54

1.1

1.3

—

Noninfective enteritis and colitis

453

1292

3.55

132.06

1.7

1.4

—

Dental caries

306

660

4.68

129.31

2.6

1.2

—

Malignant neoplasm of other and unspecified parts of biliary tract, excluding all cancers (controls excluding all cancers)

39.29

128.72

1.4

1.1

—

Malignant neoplasm of colon, excluding all cancers (controls excluding all cancers)

168

205

8.35

127.70

1.1

1.3

—

Ulcerative colitis (strict definition, require KELA, min 2 HDR)

230

403

5.86

125.17

1.7

1.5

—

Autoimmune diseases related-to ILD

675

2196

2.73

122.14

1.5

1.3

—

Ulcerative colitis (strict definition, require KELA)

231

427

5.55

118.70

1.7

1.5

—

Autoimmune diseases

816

1610

2.61

116.36

1.4

1.3

—

UC patients in KELA-register ( KELA 208 prior to 1994, or ICD K51)

236

459

5.26

114.56

1.7

1.4

—

L04AX Other immunosuppressants

489

1599

3.09

114.40

1.5

1.4

—

Adenocarcinoma and ductal carcinoma of pancreas, excluding all cancers (controls excluding all cancers)

26.42

113.20

1.1

1.5

—

Benign neoplasm of other and ill-defined parts of digestive system

167

237

7.19

111.54

1.4

1.3

—

Malignant neoplasm of pancreas

116

104

11.69

111.32

1.0

1.3

—

Nonalcoholic steatohepatitis

63.12

111.13

1.7

1.0

—

Dentinal caries

263

574

4.64

110.40

2.6

1.2

—

Colorectal adenocarcinoma, excluding all cancers (controls excluding all cancers)

158

214

7.51

109.90

1.1

1.3

—

Ulcerative colitis, NAS

192

322

6.12

109.39

1.9

1.5

—

Septicaemia

329

846

3.78

104.73

1.8

1.2

—

Adenocarcinoma of pancreas, excluding all cancers (controls excluding all cancers)

30.95

104.22

1.0

1.2

—

Used for control exclusion in common control thyroid runs

759

1519

2.55

103.63

1.4

—

Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified (FINNGEN)

424

789

3.44

103.51

2.0

1.2

—

Persons encountering health services for specific procedures and health care

782

2007

2.43

102.85

1.3

1.4

—

Persons with potential health hazards related to family and personal history and certain conditions influencing health status

719

1974

2.49

102.33

2.1

1.1

—

Other septicaemia

300

773

3.86

98.65

1.8

1.2

—

Symptoms and signs involving the digestive system and abdomen

711

1424

2.52

94.44

1.5

1.3

—

Opioids

681

1419

2.53

93.16

1.4

1.3

—

Colon adenocarcinoma, excluding all cancers (controls excluding all cancers)

106

108

10.02

92.68

1.1

1.4

—

6-mercaptopurine

14.82

90.23

1.5

1.4

—

Explicit Sepsis

340

996

3.31

88.35

1.8

1.2

—

Benign neoplasm of colon, rectum, anus and anal canal

326

656

3.58

87.94

1.6

1.4

—

Benign neoplasm: Colon

291

590

3.81

87.78

1.6

1.4

—

Benign neoplasm: Liver/bile ducts

20.90

85.87

1.3

1.2

—

Certain infectious and parasitic diseases

694

1440

2.43

85.74

1.5

1.3

—

Aplastic and other anaemias

343

1026

3.20

84.38

1.7

1.3

—

Benign neoplasm: Liver

21.02

83.30

1.3

1.2

—

Benign neoplasms

463

915

2.88

82.29

1.6

1.4

—

Malignant neoplasm, without specification of site, excluding all cancers (controls excluding all cancers)

15.24

81.26

1.1

1.3

—

Cholelithiasis, broad definition with cholecystitis

577

1609

2.47

81.23

1.5

1.2

—

Diseases of oesophagus, stomach and duodenum

732

1990

2.25

80.83

1.7

1.3

—

Toxic liver disease

29.04

80.70

1.7

1.1

—

Congenital malformations of gallbladder, bile ducts and liver

32.16

80.69

3.2

1.3

—

Insulin medication

439

1376

2.75

80.59

1.7

1.3

—

Crohn disease

161

306

5.38

80.36

1.8

1.5

—

Adenocarcinoma and ductal carcinoma of pancreas

12.97

80.34

1.1

1.3

—

Examination and observation for other reasons

463

1018

2.79

79.34

1.6

1.2

—

Ulcerative colitis (strict definition, all Crohn cases excluded)

169

344

5.02

77.98

1.5

—

Cholelithiasis

551

1585

2.45

76.77

1.4

1.2

—

Other and unspecified anaemias

309

946

3.19

76.07

1.6

1.3

—

General symptoms and signs

750

1705

2.22

75.95

1.6

1.3

—

Type 2 diabetes, wide definition

548

1464

2.46

75.06

1.5

1.3

—

Other anaemias

309

951

3.17

75.03

1.6

1.3

—

Abnormal findings on diagnostic imaging and in function studies, without diagnosis

451

1635

2.58

74.20

1.4

1.3

—

Deposits [accretions] on teeth

110

148

7.42

73.95

3.0

1.3

—

Insulin, combination of fast acting with intermediate-acting or long-acting

439

1567

2.60

73.67

1.7

1.3

—

Other ulcerative colitis

123

8.27

73.22

1.8

1.5

—

Adenocarcinoma of pancreas

13.97

73.19

1.0

1.2

—

Renal tubulo-interstitial diseases

578

1960

2.28

69.64

1.7

1.3

—

Diseases of the digestive system

338

1187

2.87

69.55

1.9

1.3

—

Benign neoplasm: Liver

14.43

68.91

1.3

1.2

—

Benign neoplasm: Liver/bile ducts

13.38

68.18

1.3

1.2

—

Other diseases of the digestive system

245

733

3.38

66.75

2.0

1.3

—

Diabetes, varying definitions

671

1882

2.14

65.87

1.5

1.3

—

Abdominal and pelvic pain

631

1422

2.24

65.85

1.5

1.3

—

Renal failure

307

957

2.96

65.60

1.9

1.3

—

GI-bleeding

241

732

3.33

64.10

2.0

1.3

—

Diabetes mellitus

667

1898

2.11

62.95

1.5

1.3

—

Abnormal results of function studies

113

198

5.87

61.76

1.4

1.5

—

Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified

630

1953

2.11

61.06

1.8

1.3

—

Hypertensive diseases (excluding secondary)

390

859

2.66

60.62

1.6

1.2

—

Implicit Sepsis

462

1548

2.33

59.38

1.8

1.3

—

Cardiovascular diseases (excluding rheumatic etc)

449

1065

2.45

59.32

1.7

1.3

—

Condition for Implicit Sepsis (Organ dysfunction codes)

536

1779

2.20

59.12

1.8

1.3

—

Benign neoplasm of other and ill-defined parts of digestive system

167

421

4.04

58.84

1.4

1.3

—

Malignant neoplasm of other and unspecified parts of biliary tract

18.43

58.17

1.4

1.2

—

Fibrosis of liver

35.06

58.14

2.1

1.0

—

Other nutritional deficiencies

437

1857

2.32

57.80

1.4

—

Abnormal findings on diagnostic imaging of other body structures

135

294

4.69

57.60

1.4

—

Alcohol use disorder, Swedish definition

383

1465

2.45

56.65

1.8

1.3

—

Heart failure, not strict

498

1544

2.24

56.44

1.9

1.3

—

Other diseases of intestines

683

1990

2.00

56.18

1.6

1.3

—

Insulin, intermediate and long-acting

364

1454

2.47

55.85

1.6

1.3

—

Type 2 diabetes

616

1772

2.07

55.82

1.5

1.3

—

Other viral hepatitis

143

6.56

55.55

1.5

1.6

—

Viral hepatitis

100

173

5.94

55.42

1.4

1.6

—

Diabetes, insuline treatment (Kela reimbursement), excluding more controls

608

1801

2.07

55.34

1.5

1.3

—

Acute renal failure

166

437

3.85

55.02

2.0

1.3

—

Colectomy operation

152

378

4.09

54.59

1.4

—

Hypertension, essential

516

1336

2.22

54.51

1.6

1.3

—

Viral hepatitis, IBD co-morbidity

118

7.14

54.32

1.4

1.3

—

Colorectal adenocarcinoma

158

408

3.93

53.82

1.1

1.3

—

Other Crohn's disease

145

6.37

53.58

1.8

1.6

—

Direct fill therapy

143

345

4.22

53.52

2.8

1.4

—

Obesity and other hyperalimentation

413

1802

2.28

53.08

1.4

—

Hypertension

528

1383

2.17

53.05

1.6

1.3

—

Hypertensive diseases

528

1384

2.17

52.99

1.6

1.3

—

Obesity

411

1795

2.28

52.80

1.4

—

Nausea and vomiting

181

510

3.52

52.61

1.8

1.3

—

Iron deficiency anaemia

281

1037

2.71

51.96

1.7

1.3

—

Cholecystectomy

454

1840

2.20

51.93

1.4

1.3

—

Bacterial Sepsis

287

961

2.68

50.82

1.9

1.2

—

Hypothyroidism (congenital or acquired)

162

221

4.24

50.66

1.3

—

Nutritional anaemias

314

1216

2.53

50.58

1.7

1.3

—

Ulcerative ileocolitis

8.21

50.53

1.8

1.5

—

387

1548

2.31

50.45

1.8

1.3

—

Hypothyroidism, levothyroxine purchases

160

218

4.25

50.21

1.3

—

Hypothyroidism and >3 levothyroxin purchases

160

218

4.25

50.21

1.3

—

Colorectal cancer

177

518

3.46

50.13

1.1

1.3

—

Diabetes medication

630

1960

1.96

49.52

1.6

1.3

—

Diabetes, insulin treatment (Kela reimbursement)

624

1959

1.96

48.77

1.5

1.4

—

Implicit viral Sepsis

150

401

3.79

48.67

2.2

1.3

—

Viral Sepsis

150

401

3.79

48.67

2.2

1.3

—

Secondary uncertain malignant neoplasm

116

257

4.59

48.47

1.2

1.4

—

398

1600

2.24

48.12

1.8

1.3

—

Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified

230

356

3.26

48.05

1.5

1.2

—

Colon adenocarcinoma

106

221

4.89

47.70

1.1

1.3

—

Fentanyl

149

5.86

47.44

1.2

1.3

—

Cytomegaloviral disease

11.51

47.26

3.3

1.3

—

Type 2 diabetes, definitions combined

565

1697

2.00

46.41

1.5

1.3

—

Cytomegalovirus infection, IBD co-morbidity

11.56

46.38

3.3

1.3

—

Cardiovascular diseases

402

954

2.31

46.13

1.6

1.3

—

Malignant neoplasm of colon

123

303

4.12

44.82

1.1

1.4

—

Other and unspecified iron deficiency

219

780

2.83

44.35

1.6

1.3

—

Type 2 diabetes, strict (exclude DM1)

566

1735

1.96

44.01

1.5

1.3

—

Bleeding

494

1789

2.02

43.85

1.7

1.3

—

Chronic kidney disease

189

625

3.04

43.40

2.0

1.3

—

Type 2 diabetes, definitions combined, including avohilmo

567

1733

1.95

43.31

1.5

1.3

—

Endocrine, nutritional and metabolic diseases

502

1243

2.06

43.29

1.5

1.4

—

Chronic periapical parodontitis

169

531

3.22

42.79

2.2

1.2

—

Portal vein thrombosis

12.94

42.40

1.9

1.3

—

Malignant neoplasm of other and ill-defined digestive organs, excluding all cancers (controls excluding all cancers)

17.68

42.16

1.1

—

Benign neoplasm: Colon, unspecified

121

308

3.94

41.73

1.6

1.3

—

Implicit bacterial Sepsis

239

836

2.64

41.61

2.0

1.2

—

Metabolic disorders

578

1902

1.90

41.46

1.4

—

Chronic periodontitis

133

368

3.67

41.17

2.3

1.2

—

In situ neoplasms

167

513

3.13

40.02

1.3

—

Insulin, fast-acting

237

932

2.56

39.50

1.8

1.3

—

Obesity, other/unspecified

240

951

2.55

39.46

1.4

—

Benign neoplasms

580

1747

1.86

38.39

1.5

1.3

—

Other congenital malformations of the digestive system

115

6.07

38.38

2.9

1.4

—

Disorders of mineral metabolism

166

5.04

38.30

1.6

1.4

—

Acute pancreatitis

138

410

3.40

38.29

2.0

1.3

—

Crohn's disease NAS

136

5.49

37.45

2.0

1.7

—

Malignant neoplasm of small intestine, excluding all cancers (controls excluding all cancers)

10.62

37.08

1.1

1.3

—

Medical observation and evaluation for suspected diseases and conditions

414

1023

2.08

36.71

1.7

1.2

—

Kidney transplant status

126

5.64

36.26

2.2

1.7

—

Ulcerative enterocolitis

7.60

36.24

2.0

1.5

—

Other gastritis (incl. Duodenitis)

161

543

3.00

36.17

2.0

1.2

—

Other (not insulin) diabetes medications

543

1784

1.84

35.55

1.5

1.3

—

Other diseases of blood and blood-forming organs, wide

167

581

2.91

35.53

1.6

1.4

—

Diseases of pulp and periapical tissues

235

975

2.43

35.06

2.0

1.2

—

Intestinal stricture

201

780

2.60

34.59

1.5

1.3

—

L01XE Protein kinase inhibitors

128

5.46

34.58

1.4

1.3

—

Malignant neoplasm, without specification of site

8.75

34.53

1.1

—

Complications of surgical and medical care, not elsewhere classified

554

2227

1.79

34.39

1.6

1.3

—

Glucagon-like peptide-1 (GLP-1) analogues

314

1204

2.16

34.23

1.6

1.3

—

Insulin, fast-acting or short human

238

1004

2.39

34.17

1.8

1.3

—

Malignant melanoma, excluding all cancers (controls excluding all cancers)

220

4.18

34.04

1.2

1.3

—

Secondary malignant neoplasm of respiratory and digestive organs

13.73

33.50

1.0

1.2

—

Chronic viral hepatitis

119

5.51

32.96

1.3

1.5

—

Malignant neoplasm of respiratory system and intrathoracic organs, excluding all cancers (controls excluding all cancers)

106

237

3.78

32.90

1.3

—

Infections, IBD-co-morbidities

135

301

3.30

32.81

2.3

1.3

—

Malignant neoplasm of bronchus and lung, excluding all cancers (controls excluding all cancers)

192

4.11

32.67

1.2

—

Malignant neoplasm of skin, excluding all cancers (controls excluding all cancers)

228

632

2.48

32.67

1.3

1.4

—

Hypothyroidism, drug reimbursement

147

4.41

32.33

1.2

1.3

—

Congenital malformation of biliary tract

78.39

32.15

3.0

1.7

—

Other/unspecified cytomegaloviral diseases

10.53

32.08

3.9

1.3

—

Diarrhoea and gastroenteritis of presumed infectious origin

402

1922

1.91

31.94

1.6

1.3

—

Obesity due to excess calories

288

1355

2.14

31.89

1.4

—

Persons encountering health services in other circumstances, wide

682

2113

1.68

31.64

1.5

1.3

—

Malignant neoplasm of rectum, excluding all cancers (controls excluding all cancers)

135

5.02

31.41

1.1

1.3

—

Crohn's disease of large intestine

110

5.58

31.38

2.0

1.6

—

Benign neoplasm: Transverse colon

110

5.53

31.28

1.9

1.4

—

Other noninfective gastroenteritis and colitis

161

591

2.75

30.95

1.8

1.4

—

Crohn's disease of small intestine

146

4.82

30.66

1.8

1.5

—

Adenocarcinoma and papilloma adenocarcinoma of rectum, excluding all cancers (controls excluding all cancers)

5.86

30.51

1.1

1.4

—

Adenocarcinoma, papilloma adenocarcinoma and mucinous carcinomas of rectum, excluding all cancers (controls excluding all cancers)

5.72

30.33

1.1

1.4

—

Complications of medical and surgical care

409

2098

1.86

30.22

1.6

1.3

—

Persons encountering health services for other counselling and medical advice, not elsewhere classified

623

2110

1.69

30.15

1.5

1.3

—

Benign neoplasm of colon, rectum, anus and anal canal

338

1544

1.99

30.14

1.6

1.3

—

Benign neoplasm: Colon

293

1397

2.07

29.57

1.6

1.3

—

Intestinal infectious diseases

518

2334

1.73

29.33

1.6

1.3

—

Coagulation defects, purpura and other haemorrhagic conditions

137

477

2.90

29.20

1.7

1.4

—

Gastro-oesophageal reflux disease

370

1733

1.90

28.92

1.4

1.3

—

Constipation

492

2013

1.76

28.77

1.6

1.3

—

Complications of procedures, not elsewhere classified

442

2137

1.79

28.71

1.6

1.3

—

Acute pancreatitis (for exclusion)

138

487

2.86

28.70

2.0

1.3

—

Chronic gastritis

168

656

2.58

28.64

1.5

1.2

—

Thrombocytopenia, unspecified

151

4.60

28.53

2.0

1.4

—

Depression medications

148

244

3.07

28.49

1.5

1.3

—

Chronic pancreatitis

251

3.67

28.44

1.5

1.3

—

Paralytic ileus and intestinal obstruction

160

613

2.63

28.34

1.4

1.3

—

Crohn's disease patients in KELA-register (KELA code 209, or 208 with ICD K50)

156

4.51

28.30

1.6

—

Neuroendocrine tumor and carcinoma of small intestine, excluding all cancers (controls excluding all cancers)

15.51

28.14

1.1

—

Hypothyroidism, strict autoimmune

364

1256

1.93

28.04

1.3

—

Total colectomy

108

5.34

27.79

1.8

1.4

—

Total colectomy operation

108

5.34

27.79

1.8

1.4

—

Other disorders of fluid, electrolyte and acid-base balance

178

697

2.48

27.76

1.6

1.3

—

Purpura and other haemorrhagic conditions

106

329

3.27

27.61

1.8

1.4

—

Hepatomegaly and splenomegaly, not elsewhere classified

13.96

27.41

1.5

1.2

—

Malignant neoplasm of eye and adnexa, excluding all cancers (controls excluding all cancers)

12.84

27.41

1.3

1.2

—

Melanoma of uvea

17.54

27.41

1.3

1.2

—

Biguanides

513

1850

1.71

26.77

1.4

1.3

—

Erysipelas

271

1214

2.05

26.43

1.4

1.3

—

Chronic periodontitis, complicated

218

3.78

26.31

2.0

1.4

—

Oedema, not elsewhere classified

171

698

2.45

26.25

1.6

1.2

—

Crohn disease (strict definition, require KELA, min 2 HDR)

146

4.47

25.99

1.6

—

Crohn disease (strict definition, require KELA)

147

4.44

25.77

1.6

—

Malaise and fatigue

252

1010

2.09

25.56

1.6

1.2

—

Other malignant neoplasms of skin (=non-melanoma skin cancer), excluding all cancers (controls excluding all cancers)

186

537

2.39

24.83

1.3

1.4

—

Other disorders of teeth and supporting structures

140

538

2.63

24.76

2.3

1.2

—

Primary_lymphoid and hematopoietic malignant neoplasms

103

335

3.09

24.76

1.4

—

Antihypertensive medication - note that there are other indications

344

990

1.91

24.73

1.5

1.3

—

Malignant neoplasm of mesothelium and soft tissue, excluding all cancers (controls excluding all cancers)

5.80

24.15

1.2

1.4

—

Biological medication for rheuma

118

422

2.83

24.05

1.3

1.4

—

Osteoporosis

140

523

2.57

23.59

1.9

1.3

—

Codeine

437

1387

1.74

23.34

1.3

—

483

1816

1.67

23.17

1.4

1.3

—

COPD/asthma/ILD related pneumonia or pneumonia derived septicaemia

483

1816

1.67

23.17

1.4

1.3

—

Other symptoms and signs involving the digestive system and abdomen

100

335

3.01

22.93

1.4

1.2

—

Benign neoplasm: Ascending colon

148

4.16

22.84

1.6

1.3

—

Explicit bacterial Sepsis

197

3.70

22.83

1.9

1.3

—

Benign neoplasm: Rectum, anus and anal canal

270

3.25

22.68

1.6

1.3

—

Biliary cirrhosis, NAS

21.87

22.65

2.8

1.2

—

Disorders of calcium metabolism

121

4.54

22.46

1.6

1.3

—

Ulcerative rectosigmoiditis

187

3.74

22.23

1.5

—

Noninfectious colitis NAS

301

3.09

22.02

1.8

1.5

—

Streptococcal septicaemia

144

4.15

21.96

2.0

1.3

—

Adalimumab

227

3.44

21.88

1.3

1.5

—

Other or unspecified ileus, impaction or obstruction

111

404

2.77

21.88

1.4

1.3

—

Agranulocytosis

282

3.16

21.85

1.6

1.4

—

Malignant neoplasm of eye and adnexa

11.82

21.82

1.2

—

Basal cell carcinoma, including avohilmo, excluding all cancers (controls excluding all cancers)

175

524

2.31

21.80

1.3

—

Factors influencing health status and contact with health services

163

330

2.49

21.79

1.6

1.1

—

Benign neoplasm: Rectum

235

3.35

21.36

1.6

1.3

—

Malignant neoplasm of urinary organs, excluding all cancers (controls excluding all cancers)

126

4.32

21.29

1.3

—

Gastroduodenal ulcer

143

596

2.41

21.24

2.0

1.2

—

Pneumonias (Asthma/COPD co-morbidities)

527

2305

1.59

21.11

1.4

—

Influenza and pneumonia

556

2332

1.57

21.10

1.5

1.4

—

Other benign neoplasms of skin

144

593

2.39

21.07

1.3

1.4

—

Basal cell carcinoma, excluding all cancers (controls excluding all cancers)

170

512

2.30

21.06

1.3

—

Tumor necrosis factor alpha inhibitors

105

380

2.79

20.99

1.2

1.5

—

Other diseases of pancreas

141

4.11

20.88

1.7

1.2

—

All pneumoniae

532

2333

1.58

20.73

1.4

—

Missing teeth due to accident, extraction or parodontitis

276

3.12

20.66

2.8

1.2

—

Malignant neoplasm of breast, ER-positive, excluding all cancers (controls excluding all cancers)

155

542

2.33

20.59

1.1

1.4

—

Benign neoplasm: Caecum

113

4.47

20.55

1.6

1.4

—

Neuroendocrine tumor and carcinoma of small intestine

9.39

20.49

1.1

1.2

—

Sodium-glucose co-transporter 2 (SGLT2) inhibitors

152

665

2.30

20.39

1.3

—

Other heart diseases

255

870

1.94

20.37

1.5

1.3

—

Diseases of the skin and subcutaneous tissue

558

1779

1.58

20.31

1.4

—

Pneumonia, organism unspecified

479

2163

1.61

20.29

1.4

—

General examination and investigation of persons without complaint and reported diagnosis

343

1023

1.79

20.25

1.6

1.2

—

Malignant neoplasm of small intestine

6.79

20.17

1.1

1.2

—

Carcinoma in situ of skin

5.57

20.08

1.3

1.2

—

Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure

316

1791

1.77

20.08

1.6

1.3

—

Iron deficiency anaemia secondary to blood loss (chronic)

346

2.83

19.93

1.9

1.3

—

Abnormalities of breathing

489

1815

1.61

19.91

1.4

—

Melanoma of uvea

10.20

19.88

1.3

—

Non-Hodgkin lymphoma, all, excluding all cancers (controls excluding all cancers)

155

3.84

19.86

1.3

1.4

—

Polyarthropathies

388

1540

1.69

19.51

1.4

—

UC patients in KELA-register (code 208), prior to 1994

106

4.53

19.46

2.3

1.3

—

Dipeptidyl peptidase 4 (DPP-4) inhibitors

241

3.19

19.24

1.8

1.2

—

Pneumonia (excl. viral and due to other infectious organisms not elsewhere classified)

512

2310

1.56

19.19

1.4

—

Pain (limb, back, neck, head abdominally)

391

1154

1.70

19.18

1.5

1.4

—

Dyspnoea

450

2156

1.60

19.15

1.4

—

Care involving dialysis

151

3.83

19.02

1.7

1.6

—

Benign neoplasm: Stomach

129

4.07

18.97

1.6

1.4

—

Unspecified kidney failure

170

3.63

18.90

1.6

1.2

—

Disorders of tooth development and eruption

4.59

18.86

2.1

1.3

—

Secondary and unspecified malignant neoplasm of lymph nodes, excluding all cancers (controls excluding all cancers)

204

3.36

18.80

1.4

—

Non-small cell lung cancer, excluding all cancers (controls excluding all cancers)

146

3.77

18.77

1.2

1.3

—

Squamous cell neoplasms and carcinomas of the skin, excluding all cancers (controls excluding all cancers)

4.85

18.67

1.4

1.3

—

Failure and rejection of transplanted organs and tissues

8.67

18.54

4.5

1.7

—

Other viral diseases

174

834

2.09

18.49

2.2

1.4

—

Pulmonary heart disease, diseases of pulmonary circulation

165

777

2.14

18.49

1.2

1.3

—

Acute tubulo-interstitial nephritis

301

1527

1.75

18.47

1.4

1.3

—

Benign neoplasm: Pancreas

8.02

18.36

1.2

—

Malignant neoplasm of other and ill-defined digestive organs

12.02

18.19

1.1

1.0

—

Disorders of plasma-protein metabolism, not elsewhere classified

15.49

17.78

1.8

1.0

—

Malignant neoplasm of bladder, excluding all cancers (controls excluding all cancers)

101

4.37

17.68

1.4

1.3

—

COPD/asthma/ILD related infections

552

1818

1.52

17.40

1.4

1.3

—

COPD/asthma related infections

552

1818

1.52

17.40

1.4

1.3

—

Gout, FINNGEN

144

661

2.19

17.27

1.5

1.3

—

Hypoplasia of dental enamel, including avohilmo

10.15

17.19

2.1

2.4

—

Other diseases of hard tissues of teeth

334

1487

1.68

17.08

2.0

1.2

—

Pain in joint

291

1102

1.75

16.97

1.3

1.4

—

Other acute viral hepatitis

9.13

16.90

1.4

1.7

—

Benign neoplasm: Sigmoid colon

239

3.03

16.88

1.6

1.3

—

Malignant neoplasm of breast, HER2-negative, excluding all cancers (controls excluding all cancers)

198

656

1.98

16.73

1.1

1.4

—

Other special examinations and investigations of persons without complaint or reported diagnosis

342

1023

1.70

16.71

1.6

1.2

—

Excluding asthma or asthma-COPD overlap

429

1347

1.60

16.68

1.4

1.3

—

Malignant neoplasm of breast, excluding all cancers (controls excluding all cancers)

198

657

1.98

16.66

1.1

1.4

—

Venous thromboembolism

262

1450

1.76

16.58

1.2

1.3

—

Fungal Sepsis

5.03

16.46

1.7

1.2

—

Gout, idiopatic and unspecified

124

547

2.28

16.42

1.5

1.3

—

Hyperkalaemia

4.55

16.37

1.7

1.3

—

Pulmonary embolism

150

715

2.11

16.36

1.2

1.3

—

Persons encountering health services for examination and investigation

343

1023

1.69

16.35

1.5

1.2

—

Heart failure and antihypertensive medication

134

389

2.29

16.34

1.6

1.2

—

Malignant neoplasm of stomach, excluding all cancers (controls excluding all cancers)

5.72

16.33

1.1

1.3

—

Pulmonary heart disease

150

717

2.10

16.24

1.2

1.3

—

Certain disorders involving the immune mechanism

122

538

2.29

16.19

1.2

1.4

—

Finngen Rheumatological endpoints

510

1924

1.51

16.13

1.4

—

Molar incisor enamel hypoplasia, with caries

12.98

16.10

2.2

1.6

—

Other disorders of gingiva or/and edentulous alveolar ridge

101

4.23

16.05

2.1

1.3

—

Symptoms and signs involving the circulatory and respiratory systems

545

1825

1.50

16.04

1.5

1.4

—

Gastric ulcer

370

2.56

16.01

2.0

1.2

—

Hypertension, portal

34.99

15.90

2.5

1.0

—

Viral infections characterized by skin and mucous membrane lesions

217

1186

1.84

15.89

1.7

1.4

—

Drug-induced neutropenia

178

3.31

15.60

1.4

—

Gout

144

624

2.12

15.59

1.5

1.3

—

Implicit fungal Sepsis

5.19

15.58

1.7

1.2

—

Other disorders of skin and subcutaneous tissue

332

1876

1.63

15.55

1.6

1.3

—

Melanocytic naevi

120

535

2.25

15.50

1.5

1.4

—

Diverticular disease of intestine

345

1414

1.63

15.27

1.6

1.3

—

Small cell lung cancer, excluding all cancers (controls excluding all cancers)

9.64

15.25

1.4

1.5

—

Other reaction to severe stress, and adjustment disorders

202

1096

1.85

15.21

1.6

1.4

—

Encephalopathy

9.09

15.15

2.6

1.4

—

COPD differential diagnosis

421

1348

1.57

15.15

1.4

—

Malignant melanoma of skin, excluding all cancers (controls excluding all cancers)

181

3.23

15.13

1.1

1.3

—

Other diseases of pleura

215

1050

1.82

15.09

1.4

1.3

—

ILD differential diagnosis

420

1348

1.56

14.96

1.4

—

Cholecystitis

257

2.82

14.89

1.6

1.2

—

DVT of lower extremities and pulmonary embolism

199

1081

1.84

14.78

1.2

1.3

—

Other diseases of intestine

275

2.75

14.77

1.7

1.3

—

Other functional intestinal disorders

213

1132

1.80

14.53

1.4

1.3

—

Enlarged lymph nodes

371

2.47

14.45

1.4

1.2

—

Drug-induced cataract

5.15

14.40

2.6

1.3

—

Erosion of teeth

6.60

14.19

2.8

1.4

—

Other embolism and thrombosis

281

2.69

14.18

1.5

1.3

—

Pain, not elsewhere classified

135

655

2.07

14.13

1.4

1.2

—

Diseases of oral cavity, salivary glands and jaws

456

1550

1.51

14.10

1.6

1.2

—

Gingival hyperplasia

4.51

14.07

2.3

1.3

—

Acute peritonitis

130

3.59

14.07

2.2

1.5

—

Crohn disease (strict definition, all UC cases excluded)

107

3.89

14.07

1.6

1.4

—

Benign neoplasm of other and unspecified endocrine glands

200

3.02

14.05

1.2

1.4

—

Malignant neoplasm of kidney, except renal pelvis, excluding all cancers (controls excluding all cancers)

116

3.74

14.04

1.3

—

Pleural effusion

306

2.60

13.98

1.6

1.3

—

Neuroendocrine tumor and carcinoma of pancreas

11.51

13.92

1.0

1.3

—

Osteopathies and chondropathies

265

1514

1.67

13.77

1.6

1.3

—

Malignant neoplasm of other connective and soft tissue, excluding all cancers (controls excluding all cancers)

5.37

13.74

1.2

1.3

—

Carcinoma in situ of skin of other and unspecified parts of face

5.34

13.71

1.3

—

Carcinoma in situ of skin of trunk

8.31

13.66

1.6

1.0

—

L04AC Interleukin inhibitors

114

3.74

13.65

1.3

1.6

—

Other pulmonary diagnosis

412

1347

1.54

13.60

1.4

1.3

—

Disorders of other endocrine glands

213

1199

1.75

13.46

1.4

—

Anxiety disorders, excluding more controls

420

1854

1.51

13.42

1.5

1.4

—

Diseases of peritoneum

233

2.82

13.40

2.0

1.4

—

Persons encountering health services in other circumstances

187

1031

1.82

13.40

1.4

1.3

—

Secondary hypertension

143

3.36

13.31

2.0

1.3

—

Other blood glucose lowering drugs, excl. Insulins

362

2.42

13.26

1.3

1.2

—

345

2.46

13.19

1.5

1.3

—

Benign neoplasm: Adrenal gland

103

3.83

13.16

1.0

1.5

—

Leiomyoma of uterus

200

617

1.83

13.13

1.3

1.4

—

Non-follicular lymphoma, hilmo, excluding all cancers

104

3.78

12.97

1.1

1.4

—

Sarcoidosis

361

2.40

12.89

1.2

1.4

—

Carcinoid syndrome

8.50

12.87

1.1

1.2

—

Asthma, unspecified (mode), excluding more controls

246

1154

1.68

12.83

1.3

—

Non-small cell lung cancer, adenocarcinoma, excluding all cancers (controls excluding all cancers)

4.59

12.83

1.2

1.3

—

Infections of the skin and subcutaneous tissue

286

1786

1.60

12.78

1.4

—

Type 1 diabetes

129

640

2.02

12.71

1.3

1.4

—

Malignant neoplasm of gallbladder, excluding all cancers (controls excluding all cancers)

26.07

12.66

1.5

1.0

—

Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity

140

3.32

12.58

1.3

—

Artificial opening status

107

3.70

12.50

1.6

1.2

—

Systemic connective tissue disorders

169

928

1.83

12.36

1.3

—

Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure

273

1707

1.60

12.36

1.6

1.3

—

Diseases of arteries, arterioles and capillaries (FINNGEN)

121

405

2.10

12.28

1.6

1.2

—

Benign neoplasm: Colon, unspecified

121

596

2.04

12.25

1.6

1.2

—

Benign neoplasm: Descending colon

4.20

12.25

1.3

1.4

—

Gout, strict definition

376

2.33

12.22

1.5

1.3

—

Disorders of lipoprotein metabolism and other lipidaemias

385

1612

1.51

12.22

1.3

1.4

—

In situ neoplasms

167

918

1.83

12.18

1.3

—

Erosion of teeth, including avohilmo

436

2.21

12.16

1.6

1.2

—

Viral warts

246

2.67

12.12

1.8

1.4

—

Anxiety disorders

446

2181

1.45

12.12

1.5

1.4

—

Hypothyreosis and Thyroxine purchase for inclusion criteria

441

1999

1.46

12.12

1.3

1.4

—

Headache

287

1516

1.59

12.11

1.4

1.3

—

Combinations of oral blood glucose lowering drugs

139

723

1.93

12.05

1.4

1.3

—

Neurotic, stress-related and somatoform disorders

442

2167

1.45

12.05

1.5

1.4

—

Malignant melanoma

330

2.41

12.00

1.2

1.4

—

Use of hypnotics and sedatives

525

2151

1.41

11.91

1.4

—

Gout, unspecified

444

2.20

11.90

1.5

1.2

—

Molar incisor enamel hypoplasia

4.46

11.81

1.9

1.6

—

Benign neoplasm: Transverse colon

221

2.74

11.81

1.9

1.4

—

Hypothyroidism, other/unspecified

429

1947

1.46

11.75

1.3

1.4

—

Benzodiazepine use

473

2370

1.42

11.56

1.4

—

Haemorrhage from respiratory passages

161

823

1.82

11.54

1.7

1.3

—

Asthma, excluding more controls

361

1272

1.52

11.50

1.4

1.3

—

Abnormal findings on diagnostic imaging of lung

207

1198

1.69

11.48

1.4

1.3

—

Covid-19 confirmed case

139

737

1.90

11.40

1.9

1.4

—

Acute upper respiratory infections of multiple and unspecified sites

361

1819

1.49

11.32

1.5

1.4

—

Functional dyspepsia

129

669

1.94

11.31

1.4

1.2

—

Extracorporeal dialysis

130

3.27

11.24

1.7

1.6

—

Asthma, unspecified (mode)

246

1210

1.62

11.17

1.3

—

Substance abuse, excluding more controls

273

1528

1.57

11.09

1.5

1.4

—

Sulfonylureas

148

637

1.86

11.08

1.3

1.2

—

Hydronephrosis

223

2.67

11.06

1.1

1.3

—

Postprocedural disorders of digestive system, not elsewhere classified

4.32

11.05

2.0

1.3

—

Hypoplasia of dental enamel , including avohilmo

4.46

11.03

1.9

1.6

—

Dermatitis

287

1870

1.54

10.95

1.5

1.3

—

Misadventures to patients during surgical and medical care

326

2.35

10.92

1.5

1.4

—

Elevated blood glucose level

153

3.04

10.91

1.7

1.5

—

Benign leiomyoma with endometriosis

278

2.46

10.85

1.4

1.3

—

Drugs, medicaments and biological substances causing adverse effects in therapeutic use

198

2.75

10.75

1.5

1.4

—

Other endocrine disorders

138

3.11

10.73

1.5

1.6

—

Parodontitis or operation codes

424

2190

1.43

10.71

1.6

1.3

—

Cutaneous abscess, furuncle and carbuncle

128

676

1.90

10.67

1.4

—

Haemolytic anaemias

3.97

10.61

1.4

1.3

—

Malignant neoplasm of eye, brain and central nervous system, excluding all cancers (controls excluding all cancers)

100

3.53

10.58

1.2

1.6

—

Chronic periodontitis, including avohilmo

421

2189

1.43

10.53

1.6

1.3

—

Diagnoses used for exclusion with ILD

126

666

1.90

10.48

1.4

1.3

—

Exposure to unspecified factor

454

2515

1.40

10.45

1.5

1.4

—

Lung cancer and mesothelioma

379

2.13

10.45

1.2

—

Parodontitis

422

2191

1.42

10.42

1.6

1.3

—

Other systemic involvement of connective tissue (FG)

124

649

1.91

10.40

1.2

1.3

—

Hernia of abdominal wall

212

1304

1.63

10.40

1.7

1.4

—

Adenocarcinoma, papilloma adenocarcinoma and mucinous carcinomas of rectum

202

2.70

10.36

1.1

1.3

—

Hypothyroidism, strict autoimmune, 3 medication purchases required

393

1861

1.44

10.36

1.3

—

Disorders of the thyroid gland

445

2064

1.41

10.32

1.3

1.4

—

Adenocarcinoma and papilloma adenocarcinoma of rectum

197

2.72

10.30

1.1

1.3

—

Any operation in hilmo

14.63

10.29

1.1

1.0

—

Persons encountering health services for specific procedures, not carried out

159

2.92

10.23

2.0

1.6

—

Asthma

365

1333

1.47

10.17

1.4

—

Glomerular disorders in diseases classified elsewhere

251

2.49

10.15

1.4

1.5

—

Melanocytic naevi of trunk

188

2.73

10.06

1.7

1.4

—

Neuroendocrine tumor and carcinoma of pancreas, excluding all cancers (controls excluding all cancers)

17.89

10.04

1.0

—

Cardiac arrhythmias

281

1212

1.54

10.01

1.5

1.3

—

Drug-induced osteoporosis

6.30

10.00

1.8

1.1

—

Mood disorders, excluding more controls

453

1972

1.40

9.93

1.5

1.3

—

Hypo-osmolality and hyponatraemia

358

2.21

9.93

1.6

1.3

—

Hypokalaemia

236

2.52

9.91

1.8

1.3

—

Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure

213

2.61

9.88

1.8

1.4

—

malignant neoplasm of female genital organs, excluding all cancers (controls excluding all cancers)

286

2.35

9.81

1.2

1.3

—

Enteropathic arthropathies

4.77

9.81

1.8

1.4

—

Malignant neoplasm of retroperitoneum and peritoneum, excluding all cancers (controls excluding all cancers)

6.97

9.77

1.1

—

Substance abuse

273

1725

1.52

9.74

1.5

1.4

—

SLE (Finngen)

4.12

9.72

1.2

1.4

—

Dermatitis and eczema

510

2454

1.36

9.72

1.5

1.4

—

Polyneuropathies and other disorders of the peripheral nervous system

104

530

1.97

9.68

1.7

1.3

—

Gingivitis and periodontal diseases

421

1534

1.42

9.66

1.5

1.2

—

Collagenous colitis

206

2.60

9.47

1.8

1.3

—

Atrial fibrillation and flutter

144

523

1.80

9.46

1.4

1.2

—

Mixed connective tissue disease

161

2.83

9.44

1.4

1.3

—

Other and unspecified dermatitis

238

1541

1.55

9.44

1.5

1.3

—

541

2114

1.35

9.42

1.4

1.3

—

Malignant neoplasm of rectum

195

2.64

9.41

1.0

1.3

—

Other problems related to primary support group, including family circumstances

302

2.28

9.38

1.8

1.5

—

Diseases of spleen

4.80

9.36

1.7

1.2

—

Diaphragmatic hernia

164

973

1.69

9.31

1.5

1.3

—

Malignant neoplasm of head and neck, excluding all cancers (controls excluding all cancers)

114

3.18

9.30

1.3

—

Malignant neoplasm of rectosigmoid junction, excluding all cancers (controls excluding all cancers)

5.75

9.30

1.1

1.3

—

Benign neoplasm: Pancreas

4.12

9.29

1.2

—

Sulfasalazine

121

658

1.85

9.27

1.3

—

Benign lipomatous neoplasm

491

1.98

9.21

1.4

—

Mental and behavioural disorders due to psychoactive substance use

279

1772

1.49

9.15

1.5

1.4

—

Laparoscopic left hemicolectomy

4.70

9.13

1.2

1.3

—

L02BG Aromatase inhibitors

139

795

1.76

9.03

1.1

1.3

—

Bronchitis

490

2373

1.36

9.02

1.5

1.3

—

L02BA Anti-estrogens

462

2.00

8.98

1.1

1.3

—

Medicines for HER+ breast cancer

167

981

1.67

8.91

1.1

1.3

—

Mycoses

127

711

1.79

8.88

1.5

1.3

—

Exclusions for E4_PCOS_CONSORTIUM

335

1459

1.44

8.76

1.3

1.4

—

Vascular disorders of the intestines

119

3.05

8.69

2.1

1.2

—

Mood [affective] disorders

480

2339

1.35

8.69

1.5

1.4

—

Follow-up examination after treatment for conditions other than malignant neoplasms

201

823

1.60

8.69

1.4

1.2

—

Other diseases of anus and rectum

130

737

1.77

8.68

1.4

1.3

—

Other specified/unspecified systemic involvement of connective tissue

130

2.96

8.66

1.4

1.2

—

Unspecific neurodegenerative disorder

585

0.33

8.66

1.0

1.2

—

Mood disorders

480

2340

1.35

8.59

1.5

1.4

—

Depression

448

2269

1.36

8.56

1.5

1.4

—

Sicca syndrome [Sjögren]

229

2.42

8.55

1.3

—

Pain in throat and chest

396

1740

1.39

8.53

1.5

1.4

—

Other diseases of stomach and duodenum

126

2.97

8.51

1.6

1.2

—

Asthma (mode)

350

1348

1.43

8.51

1.4

—

Other bacterial intestinal infections

410

2.04

8.49

1.8

1.3

—

Candidiasis

325

2.17

8.43

1.6

1.4

—

Acquired haemolytic anaemia

4.05

8.38

1.3

—

Codes for special purposes

201

1292

1.56

8.30

1.8

1.3

—

Other heart diseases, wide

451

2066

1.36

8.28

1.5

1.4

—

Cerebrovascular diseases (FINNGEN)

139

575

1.74

8.24

1.5

1.2

—

Cystitis

387

1705

1.39

8.24

1.4

1.3

—

Right hemicolectomy

118

3.00

8.20

1.2

1.3

—

Other and unspecified polyneuropathies, also in other diseases

450

1.97

8.19

1.7

1.3

—

Provisional assignment of new diseases of uncertain etiology

200

1288

1.56

8.19

1.8

1.3

—

Duodenal ulcer

216

2.42

8.13

2.1

1.2

—

Continuous positive airway pressure

429

1.92

8.05

1.3

1.4

—

Hernia

432

2165

1.36

8.05

1.5

1.4

—

Carcinoma in situ of other and unspecified sites

5.61

8.03

1.2

1.6

—

Benign neoplasm: Small intestine

4.17

8.01

1.5

1.2

—

Dental pulpitis 4

506

1976

1.33

8.00

1.4

1.3

—

Glomerular diseases

455

1.94

7.95

1.4

—

Other systemic involvement of connective tissue

125

722

1.74

7.91

1.2

1.3

—

Genitourinary diseases

303

1049

1.45

7.89

1.7

1.4

—

Pure hypercholesterolaemia

315

1486

1.43

7.88

1.3

1.4

—

Volume depletion

160

2.64

7.86

1.5

1.3

—

Bacterial intestinal infections, IBD co-morbidities

430

1.96

7.82

1.8

1.3

—

Multiple myeloma, Monoclonal gammopathy of undetermined significance (MGUS), excluding all cancers (controls excluding all cancers)

3.32

7.79

1.5

—

Unspecified haematuria

182

991

1.58

7.76

1.4

1.3

—

Dementia

665

0.40

7.76

1.0

1.2

—

Dental pulpitis 1

504

1978

1.33

7.73

1.4

1.3

—

Neurological diseases, wide definition

164

497

1.66

7.72

1.3

1.4

—

Diseases of pulp and periapical tissues, including avohilmo

503

1974

1.33

7.71

1.4

1.3

—

Diffuse large B-cell lymphoma, excluding all cancers (controls excluding all cancers)

4.36

7.69

1.1

1.4

—

Diffuse large B-cell lymphoma, helper endpoint

4.36

7.69

1.1

1.4

—

Other soft tissue disorders, not elsewhere classified

425

1946

1.35

7.66

1.5

1.4

—

Idiopathic gout

174

2.55

7.66

1.4

1.3

—

Mental and behavioural disorders due to alcohol, excluding acute intoxication

202

1324

1.53

7.65

1.6

1.4

—

malignant neoplasm of male genital organs, excluding all cancers (controls excluding all cancers)

231

2.07

7.60

1.3

1.6

—

Benign neoplasm: Caecum

211

2.39

7.59

1.6

1.4

—

Malignant neoplasm of breast, HER-positive

155

945

1.62

7.59

1.1

1.3

—

Other and unspecified drugs and medicaments

193

2.46

7.57

1.4

—

Carcinoma in situ, bladder

5.66

7.55

1.2

1.6

—

COPD (mode)

133

623

1.70

7.52

1.2

1.3

—

Psoriatic and enteropathic arthropathies

321

2.10

7.50

1.4

—

Benign neoplasm of middle ear and respiratory system

103

3.03

7.46

1.2

1.4

—

Malignant neoplasm of mesothelium and soft tissue

3.22

7.41

1.1

1.3

—

Any mental disorder

532

2039

1.31

7.41

1.5

1.3

—

Systemic lupus erythematosus

3.38

7.40

1.2

1.4

—

Symptoms and signs involving the skin and subcutaneous tissue

302

2146

1.40

7.38

1.5

1.3

—

Asthma (only as main-diagnosis), excluding more controls

303

1272

1.42

7.36

1.3

—

Intrahepatic Cholestasis of Pregnancy (ICP) , excluding more controls

154

2.62

7.36

1.4

—

Benign neoplasm: Stomach

227

2.31

7.33

1.6

1.3

—

Seborrhoeic keratosis

100

555

1.81

7.29

1.9

1.3

—

Sub-endpoint used in defining T1D endpoints

133

786

1.67

7.29

1.3

1.4

—

Cellulitis

100

555

1.81

7.29

1.4

1.5

—

Benign neoplasm: Skin of eyelid, including canthus

222

2.31

7.22

1.1

1.4

—

Disorders of oesophagus in diseases classified elsewhere

4.56

7.21

2.4

1.0

—

Malignant neoplasm of oesophagus, excluding all cancers (controls excluding all cancers)

4.75

7.17

1.1

1.6

—

Acute upper respiratory infections

471

2245

1.32

7.16

1.4

1.3

—

Psychiatric diseases

526

2024

1.30

7.14

1.5

1.4

—

Laparoscopic right hemicolectomy

117

2.85

7.12

1.1

1.3

—

Viral and other specified intestinal infections

470

1.86

7.03

1.7

1.4

—

Other diseases of gallbladder

3.11

7.02

1.8

1.1

—

Other pleural conditions

188

2.41

7.00

1.7

1.4

—

Benign neoplasm: Ascending colon

290

2.12

7.00

1.6

1.4

—

Paralytic ileus

3.33

6.98

1.4

1.3

—

Disorders of iron metabolism

4.96

6.97

1.5

1.2

—

Benign neoplasm: Duodenum

4.91

6.95

1.6

1.4

—

Urticaria and erythema

167

1075

1.56

6.95

1.2

1.4

—

Vitamin deficiency

3.02

6.93

1.8

1.2

—

Vitamin deficiency, wide

3.02

6.93

1.8

1.2

—

Ulcerative proctitis

130

2.72

6.93

1.7

1.6

—

Anaemia in chronic diseases classified elsewhere

4.03

6.92

1.5

1.3

—

Hodgkin lymphoma

4.01

6.91

1.2

1.6

—

Mental and behavioural disorders due to alcohol

227

1517

1.46

6.90

1.5

1.4

—

Spondyloarthritis

401

1.93

6.86

1.2

1.4

—

Thyroiditis, ILD-related definition

273

2.14

6.83

1.3

1.4

—

Malignant neoplasm of eye, brain and central nervous system

3.00

6.82

1.2

1.7

—

Ductal carcinoma of pancreas, excluding all cancers (controls excluding all cancers)

17.36

6.81

1.1

1.0

—

Symptoms and signs involving the urinary system

328

1855

1.37

6.74

1.5

1.4

—

Parodontitis and operation codes

378

2198

1.34

6.73

1.6

1.3

—

Gastrointestinal stromal tumor and sarcoma, excluding all cancers (controls excluding all cancers)

7.32

6.73

1.1

—

Other disorders of urethra and urinary system

301

1627

1.39

6.71

1.4

1.3

—

Disorder of lipoprotein metabolism, unspecified

282

2.10

6.69

1.3

—

Malignant neoplasm of breast, HER2-negative

213

1061

1.48

6.66

1.1

1.3

—

Type 1 diabetes, wide definition, subgroup 1

505

1.81

6.65

1.4

1.3

—

Malignant neoplasm of prostate, excluding all cancers (controls excluding all cancers)

206

2.04

6.64

1.4

1.5

—

Early onset COPD, excluding more controls

528

1.79

6.61

1.3

—

Drug-induced osteoporosis with pathological fracture

4.26

6.60

2.7

1.0

—

Depression or dysthymia

335

1370

1.37

6.57

1.5

1.4

—

Type 1 diabetes, wide definition

559

1.76

6.54

1.3

1.4

—

N06DA Anticholinesterases

496

0.33

6.49

1.0

1.2

—

Use of anticholinesterases

496

0.33

6.49

1.0

1.2

—

Malignant neoplasm of oral cavity, excluding all cancers (controls excluding all cancers)

3.67

6.47

1.1

1.4

—

SLE, ICD10

3.17

6.46

1.2

1.4

—

SLE, strict definition

3.17

6.46

1.2

1.4

—

Other and unspecified types of non-Hodgkin lymphoma, hilmo, excluding all cancers

3.95

6.44

1.2

1.5

—

Carcinoma in situ of skin

153

2.50

6.43

1.3

—

Obesity related asthma

156

1008

1.55

6.43

1.3

1.4

—

Benign neoplasm: Parotid gland

2.93

6.42

2.2

1.4

—

Primary_lymphoid and hematopoietic malignant neoplasms

103

600

1.72

6.42

1.4

1.3

—

Alcohol use disorder, ICD-based

183

1224

1.50

6.42

1.5

1.4

—

Phlebitis and thrombophlebitis (not including DVT)

557

1.75

6.36

1.3

—

Other abnormalities of plasma proteins

5.56

6.31

1.8

1.2

—

Other antidepressants

473

1906

1.30

6.30

1.4

—

Coeliac disease

296

2.04

6.28

1.5

1.4

—

Small cell lung cancer

3.88

6.28

1.4

1.2

—

Small cell lung cancer, helper endpoint

3.88

6.28

1.4

1.2

—

Asthma (only as main-diagnosis)

304

1333

1.38

6.28

1.3

1.4

—

Benign neoplasm: Rectum, anus and anal canal

487

1.79

6.24

1.6

1.3

—

Carcinoma in situ of other and unspecified digestive organs

4.73

6.23

1.4

1.3

—

Benign neoplasm of eye and adnexa

138

2.55

6.19

1.4

—

Malignant neoplasm of gallbladder

13.24

6.17

1.3

1.0

—

Vitamin B12 deficiency anaemia

194

2.28

6.11

1.3

1.2

—

Benign neoplasm of major salivary glands

133

2.57

6.11

2.1

1.4

—

Other diseases of urinary system

459

2000

1.29

6.09

1.4

—

Malignant neoplasm of ovary, excluding all cancers (controls excluding all cancers)

105

2.78

6.05

1.3

—

Adrenocortical insufficiency

3.19

6.03

1.8

1.3

—

Psoriasis (vulgaris), strict definition

3.38

6.01

1.4

1.7

—

Other complications of surgical and medical care, not elsewhere classified

228

2.16

5.99

1.8

1.3

—

Other disorders of adrenal gland

2.87

5.95

1.7

1.3

—

Malignant neoplasm of breast

215

1079

1.44

5.93

1.1

1.3

—

Benign neoplasm: Rectum

430

1.82

5.91

1.6

1.3

—

Other specific joint derangements/joint disorders

335

1681

1.34

5.88

1.3

1.4

—

Unspecified misadventure during surgical and medical care

125

2.59

5.80

1.3

1.4

—

Ventral hernia

106

641

1.66

5.80

1.5

1.3

—

Abnormal findings in nipple discharge synovial fluid wound secretions

4.46

5.79

1.9

1.0

—

Idiopathic thrombocytopenic purpura

3.19

5.76

1.8

1.4

—

Alcoholic gastritis

4.73

5.76

2.6

1.1

—

Other viral diseases, not elsewhere classified

513

1.74

5.75

2.0

1.4

—

Intrahepatic Cholestasis of Pregnancy (ICP) , incl. ICD-8, excluding more controls

206

2.20

5.75

1.4

1.3

—

Benign neoplasm: Adrenal gland

168

2.34

5.75

1.0

1.4

—

Urticaria

133

853

1.56

5.72

1.1

1.4

—

Diseases of salivary glands

486

1.76

5.71

1.6

1.2

—

Pneumothorax

132

2.52

5.70

1.3

1.5

—

Zoster [herpes zoster]

407

1.83

5.66

1.9

1.2

—

Other and unspecified psoriasis

139

2.47

5.62

1.5

—

Sleep disorders (combined)

443

2274

1.28

5.58

1.3

1.4

—

Abscess of anal and rectal regions

196

2.21

5.56

1.5

—

Intrahepatic Cholestasis of Pregnancy (ICP)

177

2.28

5.55

1.4

—

Intestinal malabsorption

2.75

5.54

1.6

1.3

—

Atrial fibrillation and flutter with reimbursement

105

403

1.67

5.54

1.4

1.2

—

Ulcer of lower limb, not elsewhere classified

290

1.98

5.53

1.5

1.4

—

External causes of morbidity and mortality

331

1243

1.34

5.49

1.5

1.3

—

Other disorders of white blood cells

129

2.50

5.46

1.3

1.4

—

Intestinal adhesions without obstruction

166

2.30

5.44

1.3

—

Dementia, including avohilmo

702

0.52

5.42

1.0

1.2

—

Dorsalgia

457

1946

1.27

5.41

1.4

—

Recurrent or chronic depression

188

939

1.45

5.40

1.5

1.4

—

Pain in limb

340

1873

1.31

5.39

1.5

1.4

—

Ductal carcinoma of pancreas

5.77

5.37

1.1

1.2

—

Use of memantine

362

0.26

5.37

1.0

1.2

—

Use of other anti-dementia drugs

362

0.26

5.37

1.0

1.2

—

Neonatal jaundice from other and unspecified causes

3.50

5.35

2.5

2.0

—

All anxiety disorders

268

1593

1.36

5.34

1.4

—

Disorders of thyroid, IBD co-morbidities

341

1.76

5.29

1.3

—

Anxiety (asthma-related co-morbidities)

266

1550

1.36

5.26

1.4

—

Secondary and unspecified malignant neoplasm of lymph nodes

175

2.24

5.26

1.4

—

Syncope and collapse

159

954

1.48

5.25

1.6

1.2

—

Other ill-defined and unspecified causes of mortality

102

2.67

5.24

1.3

—

Alzheimer disease, including avohilmo

470

0.41

5.24

1.0

1.1

—

Need for other prophylactic measures

132

2.45

5.21

1.7

1.5

—

Melanoma in situ

3.67

5.21

1.3

—

Cerebral cysts

126

2.48

5.21

2.4

1.5

—

Persons with potential health hazards related to communicable diseases

165

1122

1.46

5.20

1.5

1.4

—

Codeine or tramadol medication

507

2249

1.25

5.18

1.3

1.4

—

Clear cell adenocarcinoma of kidney, excluding all cancers (controls excluding all cancers)

3.50

5.18

1.2

1.4

—

Benign neoplasm: Middle ear, nasal cavity and accessory sinuses

3.36

5.17

1.4

1.5

—

Umbilical hernia

118

756

1.57

5.15

1.8

1.4

—

Benign neoplasm: Skin of other and unspecified parts of face

145

2.36

5.14

1.4

1.3

—

Viral pneumonia

291

1.93

5.14

1.7

1.5

—

Arthropathy in ulcerative colitis

4.29

5.12

1.5

1.4

—

Other disorders of glucose regulation and pancreatic internal secretion

177

2.22

5.12

1.6

—

Dental pulpitis 2

311

1197

1.33

5.12

1.5

1.3

—

Diseases of the musculoskeletal system and connective tissue

274

1013

1.36

5.12

1.6

1.4

—

Follow-up examination after treatment for malignant neoplasms

230

2.05

5.10

1.3

1.2

—

Benign neoplasm: Connective and other soft tissue of lower limb, including hip

4.24

5.10

1.0

1.2

—

Exclusions for E4_PCOS_BROAD

458

1.73

5.10

1.5

—

Carcinoma in situ of skin of ear and external auricular canal

13.54

5.09

1.0

—

Dental caries 1

342

1334

1.31

5.07

1.5

1.3

—

Other follicular disorders

178

2.21

5.06

1.4

1.5

—

Benign neoplasm of other and unspecified endocrine glands

321

1.88

5.06

1.2

1.4

—

Other and unspecified vasculitis limited to skin

3.32

5.05

1.2

1.3

—

Systemic sclerosis

3.45

5.04

1.5

1.4

—

Systemic sclerosis (FG)

3.45

5.04

1.5

1.3

—

Infections with a predominantly sexual mode of transmission

129

849

1.52

4.98

1.5

1.4

—

Malignant neoplasm of bronchus and lung

341

1.82

4.98

1.2

1.3

—

Benign neoplasm of mouth and pharynx

160

2.26

4.97

1.2

1.4

—

Endometriosis

159

640

1.48

4.96

1.3

—

Dermatitis due to substances taken internally

123

2.46

4.96

1.9

1.4

—

Benign lipomatous neoplasm of other sites/unspecified

105

2.58

4.96

1.3

1.4

—

Low back pain

320

1888

1.31

4.96

1.5

1.4

—

Fall on same level

522

2357

1.24

4.95

1.5

1.4

—

Other diseases of lip and oral mucosa

396

1.78

4.94

1.3

1.2

—

Other metabolic disorders

331

1.85

4.93

1.4

1.3

—

Other arthritis (FG)

133

885

1.51

4.90

1.3

1.4

—

Malignant neoplasm of other connective and soft tissue

3.38

4.90

1.2

—

Filling of root of tooth

2.95

4.89

2.4

1.3

—

Hypoglycaemia, other or unspecified

155

2.27

4.89

1.5

1.6

—

Other/unspecified dorsalgia

161

1108

1.45

4.88

1.5

1.3

—

Non-small cell lung cancer, adenocarcinoma, helper endpoint

124

2.44

4.88

1.2

1.3

—

Non-small cell lung cancer, adenocarcinoma

124

2.44

4.88

1.2

1.3

—

Dental caries, including avohilmo

340

1334

1.30

4.86

1.5

1.3

—

Hypersplenism

9.50

4.85

2.3

1.0

—

Disorders of parathyroid gland

467

1.70

4.83

1.5

1.3

—

Substance use, excluding alcohol

527

1.66

4.81

1.3

1.4

—

Carcinoma in situ of skin of trunk

3.20

4.78

1.6

1.2

—

Malignant neoplasm of respiratory system and intrathoracic organs

401

1.73

4.77

1.2

1.3

—

Osteoporosis with pathological fracture (FG)

132

2.37

4.74

2.0

1.1

—

Diseases of the respiratory system

302

1146

1.32

4.74

1.5

1.3

—

Diseases of the eye and adnexa

401

1580

1.27

4.73

1.5

1.4

—

Systemic lupus erythematosus, unspecified

2.98

4.73

1.3

1.4

—

Dental caries 2

336

2051

1.29

4.72

1.7

1.3

—

Alzheimer disease

392

0.38

4.69

1.0

1.2

—

Drug-induced adrenocortical insufficiency

3.75

4.67

2.1

1.2

—

Parodontitis or/and operation codes

277

1241

1.33

4.66

1.7

1.4

—

Deficiency of other B group vitamins

3.73

4.66

1.0

1.1

—

Secondary thrombocytopenia

4.23

4.65

1.7

1.2

—

Varicella [chickenpox]

2.60

4.64

1.7

1.6

—

Disorders of lens

298

1435

1.31

4.63

1.6

1.3

—

Falls/tendency to fall

518

2108

1.23

4.61

1.4

—

Symptoms and signs concerning food and fluid intake

205

2.06

4.61

1.1

1.3

—

Other infectious diseases

166

2.18

4.59

2.4

1.4

—

Heart failure,strict

192

994

1.40

4.56

1.4

1.2

—

Other interventions on the root canals of the tooth

3.88

4.55

2.5

1.4

—

Diseases of arteries, arterioles and capillaries

257

1443

1.33

4.55

1.6

1.3

—

Dental caries 2 and operation codes

329

2037

1.28

4.54

1.7

1.3

—

Vasculitis limited to skin, not elsewhere classified

3.09

4.53

1.2

1.5

—

Dental caries 3

359

1434

1.28

4.51

1.4

1.3

—

Other disorders starting during childhood or adolecense, excluding more controls

2.62

4.50

1.3

1.8

—

Acute posthaemorrhagic anaemia

2.89

4.50

2.3

1.2

—

Enterocolitis due to Clostridium difficile

214

2.02

4.50

1.8

1.4

—

Vocal cord dysfunction

289

1.84

4.50

1.2

—

Asthma-related infections

237

1747

1.34

4.49

1.4

—

Asthma, hospital admission 2, infections

237

1747

1.34

4.49

1.4

—

Presence of other functional implants

211

1092

1.37

4.48

1.3

1.1

—

Dental pulpitis 4, only avohilmo

490

2076

1.23

4.47

1.4

—

Monoclonal gammopathy of undetermined significance (MGUS), excluding all cancers (controls excluding all cancers)

3.29

4.47

1.4

1.3

—

Hodgkin lymphoma, hilmo

2.96

4.46

1.2

1.5

—

Benign neoplasm: Descending colon

143

2.25

4.41

1.3

1.4

—

Dental pulpitis 2, only avohilmo

313

1234

1.30

4.40

1.5

1.3

—

Emotional disorders starting during childhood or adolecense, excluding more controls

2.92

4.38

1.7

1.6

—

Asthma-related pneumonia

136

931

1.46

4.38

1.4

1.3

—

COPD

176

1038

1.40

4.37

1.2

1.3

—

Injury, poisoning and certain other consequences of external causes

270

1022

1.33

4.36

1.5

1.3

—

Non-small cell lung cancer

323

1.80

4.36

1.2

1.3

—

Intrahepatic Cholestasis of Pregnancy (ICP) , incl. ICD-8

231

1.96

4.34

1.4

—

Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk

224

1.97

4.34

1.5

1.4

—

Metabolic disorder, other/unspecified

12.34

4.34

1.7

1.3

—

Other acute lower respiratory infections

209

1474

1.36

4.34

1.5

1.4

—

Hypoplasia of dental enamel, prenatal , including avohilmo

9.28

4.33

2.0

2.3

—

Sleep apnoea, including avohilmo

424

2216

1.24

4.33

1.3

1.4

—

Gastrointestinal stromal tumor and sarcoma

4.65

4.33

1.1

1.0

—

Malignant neoplasm of urinary organs

197

2.04

4.32

1.2

1.4

—

Care involving use of rehabilitation procedures

234

1671

1.33

4.31

1.4

—

Asthma-related pneumonia or sepsis

136

934

1.46

4.31

1.4

1.3

—

Asthma, hospital admissions 3, pneumonia

136

934

1.46

4.31

1.4

1.3

—

Pruritus

260

1.89

4.29

1.6

1.3

—

Hidradenitis suppurativa

2.80

4.29

1.1

1.6

—

Parasetamol

386

1564

1.26

4.29

1.2

1.5

—

Congenital malformations, deformations and chromosomal abnormalities

248

1804

1.32

4.29

1.6

1.4

—

Other predominantly sexually transmitted diseases, not elsewhere classified

452

1.67

4.27

1.5

1.4

—

Disorders of skin appendages

200

1473

1.36

4.26

1.5

1.4

—

Cystic kidney disease

2.72

4.26

2.6

1.3

—

Systemic sclerosis, icd10

3.08

4.26

1.5

1.3

—

Dementia in Alzheimer disease

247

0.31

4.25

1.0

1.2

—

Psoriasis

121

816

1.49

4.25

1.4

—

Other other unspecified disorders of the circulatory system

2.65

4.24

1.8

1.3

—

Problems related to lifestyle

233

1.94

4.24

1.5

1.4

—

Vertebral, anorectal, cardiavascular, thracheoesophagial, renal and limb anomaly

438

1.66

4.23

1.7

1.5

—

Dental caries 1 and operation codes

375

1525

1.26

4.23

1.5

1.3

—

Alzheimer disease, excluding more controls

292

0.36

4.22

1.0

1.2

—

Other peripheral vascular diseases

179

2.08

4.20

1.3

1.4

—

Any dementia

541

0.52

4.19

1.0

1.2

—

Congenital malformations of the urinary system

140

2.23

4.18

2.2

1.6

—

Degenerative diseases of the nervous system

486

0.48

4.18

1.2

—

Haemorrhagic and haematological disorders of fetus and newborn

2.96

4.17

2.5

1.9

—

Hyperlipidaemia, other/unspecified

141

929

1.44

4.17

1.3

—

Carcinoma in situ of skin of scalp and neck

6.99

4.17

1.1

—

Procreative management

148

875

1.43

4.16

1.4

—

Any dementia, excluding more controls

513

0.51

4.16

1.0

1.2

—

Sleep apnoea

401

2190

1.24

4.15

1.3

1.4

—

Melanocytic naevi

120

812

1.48

4.15

1.5

1.4

—

Early onset COPD

604

1.56

4.14

1.3

1.4

—

Accidents

398

1595

1.25

4.14

1.4

—

Other external causes of accidental injury

398

1595

1.25

4.14

1.4

—

Other and unspecified disorders of white blood cells

2.55

4.14

1.3

1.4

—

Malignant neoplasm of stomach

2.55

4.13

1.1

1.3

—

Use of rivastigmine

215

0.23

4.08

1.0

1.2

—

Ill-defined and unknown causes of mortality

116

2.34

4.08

1.3

—

Adenocarcinoma and Papillary adenocarcinoma of kidney, excluding all cancers (controls excluding all cancers)

8.16

4.08

1.0

—

Chronic lower respiratory diseases

534

2392

1.21

4.07

1.3

1.4

—

Benign neoplasm: Sigmoid colon

436

1.66

4.05

1.6

1.3

—

Other and unspecified effects of external causes

113

760

1.49

4.04

1.4

1.5

—

Adjustment and management of implanted device

309

1.79

4.04

1.2

1.4

—

COPD, hospital admissions

166

1011

1.39

4.03

1.2

1.3

—

Benign neoplasm: Endocrine pancreas

6.67

4.03

1.0

1.3

—

Acute sinusitis

216

1514

1.33

4.02

1.6

1.4

—

COPD, early/later onset

167

1016

1.39

4.02

1.2

1.3

—

Smoking dependency

203

1.98

4.01

1.3

1.5

—

Other and unspecified acquired haemolytic anaemias

4.03

4.01

1.3

1.1

—

Carcinoma in situ of other and unspecified genital organs

3.98

3.99

1.9

1.1

—

Benign neoplasm: Choroid

2.68

3.99

1.4

—

Oesophagitis

105

2.40

3.98

1.4

1.3

—

Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis

238

1480

1.31

3.97

1.4

1.3

—

136

894

1.43

3.96

1.3

1.2

—

Acute bronchitis

154

1080

1.40

3.95

1.5

1.4

—

Malignant neoplasm of tongue, excluding all cancers (controls excluding all cancers)

3.67

3.93

1.1

1.4

—

Dental caries 3 and operation codes

391

1614

1.24

3.92

1.5

1.3

—

Mental and behavioural disorders due to tobacco

205

1.96

3.91

1.3

1.5

—

COPD-related respiratory insufficiency

233

1.90

3.91

1.6

1.3

—

Other diseases of pericardium

2.58

3.89

1.2

1.4

—

Malignant neoplasm of adrenal gland, excluding all cancers (controls excluding all cancers)

7.47

3.89

1.0

1.5

—

Neuroendocrine tumor and carcinoma of lung, excluding all cancers (controls excluding all cancers)

7.46

3.88

1.3

1.0

—

All influenza

622

1.53

3.87

1.6

1.4

—

Other and unspecified urticaria

543

1.57

3.87

1.1

1.5

—

Papulosquamous disorders

161

1168

1.38

3.84

1.3

1.4

—

Malignant neoplasm of endocrine gland, excluding all cancers (controls excluding all cancers)

152

2.12

3.84

1.0

1.4

—

Degeneration of macula and posterior pole

158

938

1.39

3.83

1.3

1.2

—

Convulsions, not elsewhere classified

553

1.56

3.82

1.6

1.3

—

Other diseases of the respiratory system

451

1.62

3.82

1.3

—

Other respiratory disorders and diseases

451

1.62

3.82

1.3

—

Non-follicular lymphoma

200

1.96

3.81

1.1

1.3

—

Carcinoma in situ of rectum

8.95

3.79

1.0

—

CR(E)ST syndrome

3.59

3.78

1.8

1.6

—

Autoimmune thyroiditis

3.57

3.78

1.1

1.4

—

Social phobias

180

2.01

3.78

1.2

1.5

—

Disorders of choroid and retina

317

1835

1.26

3.76

1.3

1.4

—

Squamous cell neoplasms and carcinomas of the skin

215

1.91

3.76

1.4

1.2

—

Familial hypercholesterolemia

339

1.72

3.75

1.4

1.3

—

Skin changes due to chronic exposure to nonionizing radiation

126

831

1.44

3.75

1.4

1.2

—

Other benign neoplasms of skin

144

1030

1.40

3.74

1.3

—

Actinic keratosis

122

803

1.45

3.74

1.3

1.2

—

Ingrowing nail

134

2.18

3.74

1.3

1.5

—

Respiratory diseases principally affecting the interstitium, IBD co-morbidites

187

1.86

3.73

1.5

1.2

—

Lower back pain or/and sciatica

426

2426

1.22

3.73

1.5

1.4

—

Malignant neoplasm of kidney, except renal pelvis

181

2.00

3.73

1.2

1.4

—

Excessive attrition of teeth

147

564

1.42

3.70

1.5

1.2

—

Infliximab

6.82

3.70

1.0

—

Alzheimer’s disease, wide definition, excluding more controls

258

0.37

3.68

1.0

1.2

—

Other skin changes

402

1.65

3.67

1.8

1.4

—

Persons with potential health hazards related to socioeconomic and psychosocial circumstances

113

768

1.46

3.66

1.7

1.4

—

Family history of malignant neoplasm

275

1.79

3.65

1.1

1.2

—

Other benign neoplasms of connective and other soft tissue

169

2.02

3.63

1.2

1.4

—

Other specified/unspecified arthritis

115

795

1.45

3.62

1.3

1.4

—

Alzheimer’s disease, wide definition

337

0.40

3.60

1.0

1.2

—

Abnormalities of heart beat

133

937

1.41

3.59

1.3

—

Hypoplasia of dental enamel, prenatal

10.84

3.57

2.3

2.5

—

180

1335

1.34

3.56

1.3

1.4

—

Other chronic obstructive pulmonary disease

165

1009

1.36

3.55

1.2

1.3

—

Malignant neoplasm of retroperitoneum and peritoneum

5.45

3.54

1.1

—

Lung transplant status

5.45

3.54

1.6

—

Lung transplantation

5.45

3.54

1.6

—

Drug-induced polyneuropathy

5.43

3.54

1.2

1.1

—

Family history of other conditions

3.91

3.53

1.0

1.2

—

Melanocytic naevi of trunk

293

1.75

3.53

1.7

1.4

—

Neuroendocrine tumor and carcinoma of lung

6.31

3.53

1.3

1.0

—

Benign neoplasm: Skin of trunk

2.83

3.52

1.2

1.4

—

Soft tissue disorders

461

1985

1.21

3.52

1.5

1.4

—

Abnormal findings on examination of urine, without diagnosis

2.34

3.51

1.3

1.5

—

Secondary malignant neoplasm of other and unspecified sites

3.61

3.50

1.0

1.3

—

Special screening examination for infectious and parasitic diseases

460

1.51

3.50

1.3

—

Carcinoma in situ of skin of other and unspecified parts of face

125

2.17

3.48

1.3

1.2

—

Dental pulpitis 1, only avohilmo

480

2090

1.20

3.45

1.3

1.4

—

Senile cataract

263

1279

1.28

3.45

1.5

1.3

—

Malignant neoplasm of breast, ER-negative, excluding all cancers (controls excluding all cancers)

385

1.63

3.44

1.2

1.4

—

Organic, including symptomatic, mental disorders

920

0.67

3.43

1.4

1.2

—

COPD related to multimorbidity

134

808

1.40

3.41

1.2

—

Multiple myeloma, excluding all cancers (controls excluding all cancers)

3.00

3.41

1.5

1.4

—

Adverse effects, not elsewhere classified

529

1.54

3.40

1.4

—

Other chronic obstructive pulmonary disease, including avohilmo

197

1247

1.32

3.39

1.2

1.3

—

Arthropathies in other diseases classified elsewhere

2.52

3.38

1.3

1.4

—

Vascular diseases of the intestine

2.59

3.38

2.6

1.4

—

Injury of intra-abdominal organs

2.86

3.37

1.5

1.4

—

Unspecified privation

253

1.79

3.36

1.7

1.5

—

Malignant neoplasm of testis, excluding all cancers (controls excluding all cancers)

3.74

3.36

1.1

1.5

—

Melanocytic naevi of other and unspecified parts of face

101

2.29

3.36

1.2

1.4

—

Alzheimer’s disease (Late onset), excluding more controls

232

0.37

3.35

1.0

1.1

—

Cough

163

1164

1.35

3.34

1.5

1.3

—

Disorders of lacrimal system

162

1206

1.35

3.34

1.4

1.3

—

Hyperparathyroidism

400

1.61

3.34

1.4

1.3

—

Presence of other devices

491

1.55

3.34

1.6

1.1

—

Other retinal disorders

231

1446

1.29

3.33

1.3

—

Other CVD

375

1.63

3.30

1.4

1.3

—

Weight loss

204

1.87

3.29

1.1

1.4

—

Localized swelling, mass and lump of skin and subcutaneous tissue

123

878

1.40

3.29

1.5

1.3

—

Hypertensive heart and/or renal disease

410

1.53

3.28

1.3

1.2

—

Fracture of skull and facial bones

582

1.50

3.27

1.3

1.4

—

Other general symptoms and signs

114

2.18

3.26

1.4

1.3

—

Personality disorders, excluding more controls

102

705

1.45

3.26

1.5

1.4

—

Other nonscarring hair loss

4.84

3.26

1.3

1.7

—

Phobic anxiety disorders

323

1.68

3.25

1.4

—

severe traumatic brain injury, does not include concussion

495

1.54

3.24

1.5

1.4

—

Lupus erythematosus

2.70

3.24

1.6

1.4

—

Other specified diseases with participation of lymphoreticular and reticulohistiocytic tissue

6.68

3.23

1.4

1.0

—

Behavioural and emotional disorders with onset usually occurring in childhood and adolescence

435

1.55

3.23

1.5

—

Charcot foot

3.20

3.23

1.3

1.4

—

Dentofacial anomalies [including malocclusion]

108

748

1.43

3.22

1.7

1.2

—

Benign neoplasm: Pituitary gland, craniopharyngeal duct

2.45

3.21

1.7

1.4

—

Melanocytic naevi of lower limb, including hip

2.59

3.21

1.5

1.4

—

Infection of intervertebral disc (pyogenic)

3.63

3.21

1.2

1.3

—

Fissure and fistula of anal and rectal regions

658

1.46

3.21

1.2

1.3

—

Anosmia

4.71

3.20

1.8

1.0

—

Viral pneumonia (unknown virus, not influenza)

150

2.01

3.20

1.7

1.5

—

Disorders of eyelid, lacrimal system and orbit

341

2190

1.22

3.19

1.4

1.3

—

Alcohol dependence

108

758

1.43

3.19

1.7

1.4

—

Other salmonella infections

2.33

3.18

1.4

1.3

—

Spondylopathies (FG)

372

1.62

3.16

1.1

1.4

—

Other respiratory diseases principally affecting the interstitium

380

1.61

3.15

1.5

1.3

—

Other abnormal findings of blood chemistry

2.37

3.15

2.0

1.4

—

Other overlap syndromes

2.99

3.15

1.1

1.4

—

Invasive ventilation

151

2.00

3.14

1.7

1.4

—

Methotrexate

304

1.68

3.13

1.1

1.3

—

Malignant neoplasm of larynx, excluding all cancers (controls excluding all cancers)

4.54

3.12

1.8

1.5

—

Excessive, frequent and irregular menstruation

161

665

1.35

3.11

1.5

1.3

—

Vitreous haemorrhage

223

1.80

3.10

1.2

1.5

—

Other diseases of blood and blood-forming organs

152

1.99

3.09

2.0

1.4

—

Hypertensive Heart Disease

381

1.55

3.09

1.3

1.2

—

Disorders of magnesium metabolism

5.14

3.08

1.3

1.2

—

Other disorders of lacrimal gland

132

966

1.37

3.07

1.4

1.3

—

Benign neoplasm: Anus and anal canal

3.26

3.06

1.2

1.4

—

Malignant neoplasm of other and ill-defined sites, excluding all cancers (controls excluding all cancers)

5.05

3.06

1.0

—

Hypertrophic disorders of skin

139

2.03

3.06

1.7

1.4

—

Infarction of spleen

6.01

3.05

1.4

1.1

—

Occupant of pick-up truck or van injured in other and unspecified transport accidents

6.01

3.05

2.6

1.0

—

Later onset COPD, excluding more controls

340

1.56

3.02

1.1

1.2

—

Other leukaemias of specified cell type

10.48

3.01

2.6

1.6

—

ILD, hospital admissions

300

1.67

3.01

1.5

1.3

—

Pseudopolyposis of colon

10.40

3.01

1.6

1.0

—

Irritable bowel syndrome

104

734

1.42

3.00

1.3

—

Injuries to the knee and lower leg

499

2428

1.18

3.00

1.4

—

conjunctival haemorrhage

168

1.92

2.99

2.1

1.4

—

Carcinoma in situ of oral cavity, oesophagus and stomach

10.22

2.99

1.0

1.6

—

Keratitis and keratoconjunctivitis in other diseases classified elsewhere

2.36

2.99

1.3

1.4

—

Malignant neoplasm of other and unspecified parts of mouth, excluding all cancers (controls excluding all cancers)

10.14

2.99

1.0

—

Nail disorders

204

1.82

2.98

1.2

1.5

—

Type 1 diabetes, strict (exclude DM2)

240

1.75

2.98

1.4

1.6

—

Herpesviral [herpes simplex] infections

286

1.69

2.97

1.6

1.4

—

Malignant melanoma of skin

241

1.75

2.97

1.1

1.4

—

Serous carcinoma of ovary, excluding all cancers (controls excluding all cancers)

2.65

2.97

1.3

1.4

—

Isolated proteinuria

2.56

2.96

1.3

1.5

—

Alzheimer’s disease (Early onset)

0.00

2.96

0.0

1.1

—

Pneumocystosis

3.19

2.94

1.8

1.1

—

Type 1 diabetes, definitions combined

241

1.74

2.94

1.4

1.5

—

Other pulmonary heart/vessel disease

2.29

2.94

1.3

—

Preparatory care for dialysis

101

2.20

2.94

1.2

1.4

—

Benign neoplasm of ovary

310

1.65

2.93

1.0

1.4

—

Appendectomy

264

2054

1.24

2.92

1.4

—

Interstitial lung disease

303

1.66

2.91

1.5

1.3

—

Interstitial lung disease endpoints

303

1.66

2.91

1.5

1.3

—

Leiomyoma of uterus

252

1143

1.26

2.91

1.3

—

Alzheimer’s disease (Late onset)

301

0.43

2.91

1.0

1.2

—

Polycystic ovarian syndrome, consortium definition

279

1360

1.24

2.89

1.4

1.3

—

Leiomyosarcoma, excluding all cancers (controls excluding all cancers)

5.48

2.88

1.1

—

Other interstitial pulmonary diseases

304

1.65

2.88

1.5

1.3

—

Asthma (diagnoses ohter than nonallergic)

348

2476

1.20

2.85

1.3

1.4

—

Haemangioma and lymphangioma, any site

157

1.92

2.84

1.7

1.5

—

Other disorders of kidney and ureter

290

1.66

2.84

1.8

1.4

—

Benign leiomyoma with endometriosis

447

1.53

2.83

1.4

1.3

—

Arthropathic psoriasis

298

1.65

2.83

1.2

1.5

—

Impacted maxillary canine

4.53

2.81

1.8

1.7

—

Perineal laceration during delivery

369

0.48

2.81

1.2

1.3

—

Parkinson's disease, strict definition, excluding more controls

296

0.40

2.79

1.2

—

Other and unspecified diseases of blood and blood-forming organs

2.57

2.79

2.9

1.3

—

Alzheimer’s disease (Early onset), excluding more controls

0.00

2.79

0.0

1.2

—

Open wound of lower leg

346

1.59

2.78

1.8

1.5

—

Fitting and adjustment of other devices

102

677

1.40

2.77

1.3

—

Inflammatory diseases of female pelvic organs

234

1411

1.25

2.76

1.5

1.3

—

Wilms' tumor, excluding all cancers (controls excluding all cancers)

8.49

2.76

1.2

1.0

—

ILD, hospital admissions 1, main diag only

262

1.69

2.75

1.5

1.3

—

Emphysema

131

1.99

2.75

1.2

1.3

—

ILD, hospital admissions 3, with pneumonia sepsis

152

1.92

2.75

1.6

1.2

—

Other and unspecified nonscarring hair loss

5.11

2.74

1.4

1.9

—

Valvular heart disease excluding rheumatic fever

186

1058

1.29

2.74

1.4

1.3

—

Disorders of adult personality and behaviour

112

815

1.38

2.74

1.5

1.4

—

Fibrosarcoma, excluding all cancers (controls excluding all cancers)

5.09

2.74

1.0

—

Carcinoma in situ of skin of lower limb, including hip

5.04

2.73

1.1

1.0

—

Benign neoplasm: Small intestine

2.16

2.71

1.5

1.2

—

Malignant neoplasm of base of tongue, excluding all cancers (controls excluding all cancers)

6.10

2.71

1.2

1.3

—

Acute suppurative otitis media

101

675

1.40

2.71

1.4

1.5

—

Ovarian cyst

150

654

1.33

2.70

1.4

1.3

—

Benign neoplasm of middle ear and respiratory system

168

1.85

2.67

1.2

1.4

—

Other joint disorders

385

1723

1.19

2.67

1.3

1.4

—

Other disorders involving the immune mechanism, not elsewhere classified

2.35

2.66

1.6

1.5

—

Dermatopolymyositis

3.17

2.66

2.1

1.4

—

Other anxiety disorders

175

1209

1.29

2.65

1.3

1.4

—

Protozoal diseases

2.41

2.64

1.6

1.3

—

All dysplastic lesions of the vulva

106

2.09

2.63

1.5

1.2

—

Lack of expected normal physiological development

2.72

2.63

1.9

1.5

—

Generalized skin eruption due to drugs and medicaments

2.17

2.61

2.2

1.4

—

Dialysis

2.17

2.61

1.8

1.4

—

Acute pharyngitis

373

1.55

2.61

1.6

—

Panic disorder

360

1.56

2.60

1.3

1.4

—

Diseases of appendix

306

2318

1.20

2.59

1.3

1.4

—

Other aneurysm

100

2.11

2.59

2.0

1.4

—

Other dialysis

2.32

2.59

2.1

1.6

—

Malignant neoplasm of bone and articular cartilage, excluding all cancers (controls excluding all cancers)

3.63

2.58

1.0

1.4

—

Other cataract

168

1010

1.29

2.58

1.5

1.3

—

Cervicobrachial syndrome

680

0.62

2.58

1.4

—

Oral lichen ruber planus, including avohilmo

149

1.89

2.56

1.1

1.3

—

Emotional disorders and disorders of social functioning with onset specific to childhood

2.10

2.56

1.7

1.6

—

Seborrhoeic dermatitis

215

1.73

2.55

2.0

1.5

—

Non-rheumatic valve diseases

183

1049

1.28

2.55

1.4

1.3

—

Benign neoplasm: Duodenum

2.44

2.55

1.6

1.2

—

Parkinson's disease, excluding more controls

322

0.45

2.54

1.1

1.2

—

Other autoimmune haemolytic anaemias

3.08

2.54

1.4

1.2

—

Parkinson's disease, strict definition

288

0.42

2.53

1.2

1.3

—

Dental operations

278

1168

1.22

2.53

1.5

1.2

—

Burns and corrosions

355

1.55

2.52

1.4

1.5

—

Special screening examination for other diseases and disorders

164

1.83

2.52

1.4

1.3

—

Arthropathies

402

1735

1.18

2.51

1.3

1.4

—

Sacroiliitis, not elsewhere classified

115

2.01

2.51

1.3

1.4

—

Appendicitis, broad definition

303

2309

1.20

2.51

1.3

1.4

—

Angina pectoris

150

1309

0.77

2.51

1.2

1.3

—

Haemangioma, any site

143

1.90

2.50

1.7

1.5

—

Chronic laryngitis and laryngotracheitis

388

1.53

2.50

1.4

—

Non-ischemic cardiomyopathy

108

650

1.37

2.49

1.5

1.2

—

Urolithiasis

118

881

1.34

2.49

1.5

1.3

—

Pneumonia due to other infectious organisms, not elsewhere classified

2.34

2.49

1.6

1.4

—

Malignant neoplasm of rectosigmoid junction

2.86

2.49

1.1

1.2

—

Malignant neoplasm of bone and articular cartilage of limbs, excluding all cancers (controls excluding all cancers)

4.44

2.48

1.0

1.2

—

Glomerulonephritis

232

1.69

2.48

1.4

1.5

—

Adenocarcinoma and Papillary adenocarcinoma of kidney

3.87

2.47

1.0

1.2

—

Irregular menses

188

1209

1.26

2.47

1.5

1.3

—

Coxarthrosis, primary

136

1537

0.77

2.47

1.3

—

Heart failure, strict

201

1154

1.26

2.47

1.4

1.3

—

Abnormal findings in secretions and smears from cervix uteri vagina vulva

189

1178

1.26

2.47

1.4

1.3

—

Other behavioural and emotional disorders with onset usually occurring in childhood and adolescence

128

1.93

2.45

1.2

1.7

—

All dysplastic lesions of the vagina

2.48

2.45

2.2

1.3

—

Insulin, fast-acting (human)

326

1.57

2.45

1.2

1.4

—

Personal history of other diseases and conditions

263

1.63

2.43

2.0

1.2

—

Injuries to the thorax

161

1260

1.28

2.42

1.5

1.4

—

Undefined dementia

147

0.31

2.42

1.0

1.2

—

Diabetic nephropathy, excluding more controls

406

1.46

2.42

1.4

—

Unspecified dementia

146

0.31

2.42

1.0

1.2

—

Paracetamol of NSAID medication

290

1.44

2.42

1.6

1.5

—

Parkinson's disease

323

0.46

2.41

1.1

1.3

—

Follow-up care involving plastic surgery

2.18

2.41

1.0

1.3

—

Lymphangioma, anys site

5.08

2.41

1.3

1.8

—

Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue

5.07

2.41

1.0

—

Other diseases of arteries and capillaries

189

1.75

2.41

2.2

1.3

—

Hypertrophic scar

124

1.95

2.40

1.6

1.4

—

Use of donepezil

297

0.45

2.40

1.0

1.2

—

Endocarditis

2.36

2.39

1.5

—

Pneumonia due to Streptococcus pneumoniae

2.12

2.39

1.4

1.5

—

L02BX Other hormone antagonists and related agents

2.12

2.39

1.1

1.4

—

Dermatopolymyositis, unspecified

6.39

2.38

2.2

1.0

—

Complex cardiac defects

4.22

2.38

1.1

2.0

—

Congenital malformations of cardiac chambers and connections

4.21

2.38

1.1

1.9

—

Arthropathy in Crohn disease

3.69

2.37

2.3

1.2

—

Diseases caused by chlamydiae

3.69

2.37

3.1

1.2

—

Other diseases of peritoneum

2.07

2.37

1.4

1.3

—

Malignant neoplasm of skin

214

1302

1.24

2.37

1.2

1.3

—

Abnormal weight loss

190

1.74

2.37

1.1

1.4

—

Benign neoplasm: Connective and other soft tissue of lower limb, including hip

2.52

2.36

1.0

1.3

—

Benign neoplasm of thyroid gland

2.52

2.36

1.1

1.2

—

Other symptoms and signs involving the circulatory and respiratory systems

132

1.90

2.35

1.5

1.4

—

Extreme obesity with alveolar hypoventilation

2.16

2.35

2.1

1.4

—

Parodontitis, under 40 years

183

1.75

2.35

1.5

—

Parodontitis, under 40 years, or operation codes

183

1.75

2.35

1.5

—

Other disorders starting during childhood or adolescence

124

1.93

2.35

1.3

1.7

—

Acute appendicitis

283

2228

1.20

2.35

1.3

1.4

—

COPD, hospital admission 2, with asthma infections

103

647

1.36

2.35

1.2

1.3

—

Contraceptive management

178

991

1.26

2.34

1.5

—

ILD, hospital admission 2, with pulmonary infections

191

1.73

2.33

1.6

1.4

—

Varicose veins of other sites

147

1.85

2.33

2.2

1.4

—

Burns and corrosions of external body surface, specified by site

260

1.62

2.32

1.4

1.5

—

Lichen simplex chronicus and prurigo

140

1.87

2.32

1.0

1.3

—

Malignant neoplasm of corpus uteri, excluding all cancers (controls excluding all cancers)

133

1.89

2.31

1.0

1.3

—

Nerve, nerve root and plexus disorders

427

2311

1.16

2.30

1.3

1.4

—

Scar conditions and fibrosis of skin

2.13

2.29

1.5

1.3

—

Transient ischemic attack

114

1245

0.76

2.28

1.3

—

Dorsopathies

450

1983

1.16

2.28

1.4

—

Abnormality of white blood cells, not elsewhere classified

4.69

2.28

1.2

1.3

—

Basal cell carcinoma

185

1179

1.25

2.28

1.3

1.2

—

Volvulus

2.47

2.28

1.4

1.3

—

Malignant immunoproliferative diseases

4.68

2.28

2.0

1.2

—

Calcific aortic valvular stenosis, operated

607

1.39

2.28

1.4

1.2

—

Calcific aortic valvular stenosis

607

1.39

2.28

1.4

1.2

—

Benign neoplasm: Skin of ear and external auricular canal

2.70

2.28

1.3

1.2

—

Scleritis

3.52

2.28

1.8

1.1

—

Psoriatic arthropathies

285

1.58

2.27

1.3

1.4

—

Calculus of kidney and ureter

110

826

1.33

2.27

1.5

1.3

—

Multiple myeloma and malignant plasma cell neoplasms

2.56

2.27

1.6

1.4

—

Other coagulation defects

163

1.79

2.27

1.6

1.4

—

Carcinoma in situ of rectum

3.96

2.26

1.0

1.2

—

Hyperkinetic disorders, excluding more controls

202

1.69

2.26

1.7

1.5

—

Pain and other conditions associated with female genital organs and menstrual cycle

531

1.41

2.26

1.3

—

Assault

325

1.54

2.26

1.3

1.5

—

Other CVD (FINNGEN)

168

1.69

2.26

1.1

1.2

—

Short Achilles tendon (acquired)

0.00

2.25

0.0

1.3

—

Other leukaemias of specified cell type

5.81

2.24

2.6

1.3

—

Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care

186

1.73

2.24

1.5

1.4

—

Infectious mononucleosis

186

1.73

2.24

1.7

1.5

—

Psoriasis vulgaris

514

1.42

2.23

1.5

1.4

—

Carcinoma in situ of oral cavity, oesophagus and stomach

5.67

2.22

1.0

—

Benign neoplasm: Ill-defined sites within the digestive system

5.66

2.22

1.0

1.1

—

Myocarditis

2.10

2.22

1.6

1.3

—

Malignant neoplasm of renal pelvis, excluding all cancers (controls excluding all cancers)

5.61

2.22

1.2

1.0

—

Other disorders of veins

137

1064

1.29

2.21

1.3

1.2

—

All influenza (not pneumonia)

375

1.50

2.21

1.5

1.4

—

Menorrhagia

145

621

1.29

2.21

1.4

1.3

—

Helminthiases

2.81

2.21

1.8

1.4

—

Hypertrophy of breast in women and men

574

1.40

2.21

1.4

1.3

—

Specific development disorders of scholastic skills

2.01

2.19

2.0

1.5

—

Other congenital malformations of intestine

3.39

2.19

1.9

1.1

—

Maternal care for other conditions predominantly related to pregnancy

592

1.39

2.19

1.5

1.3

—

Benign neoplasm: Other/unspecified site

3.37

2.18

1.0

1.2

—

Disorder of external ear, unspecified

2.26

2.18

1.3

1.4

—

Carcinoma in situ of other and unspecified sites

2.25

2.18

1.2

1.4

—

Disorders of psychological development

289

1.54

2.16

1.5

—

Calcific aortic valvular stenosis, diagnosis (helper)

605

1.38

2.16

1.4

1.2

—

Operations 2 for CAVS

605

1.38

2.16

1.4

1.2

—

Benign neoplasm: Tonsil

3.73

2.16

1.1

1.2

—

Speech and linguistic disorders, excluding more controls

184

1.70

2.16

1.7

1.5

—

Unspecified fall

173

1377

1.25

2.16

1.3

1.4

—

Immunodeficiencies

115

1.92

2.16

1.1

1.5

—

Other juvenile arthritis

101

1.99

2.15

1.8

1.6

—

Dermatopolymyositis (FG)

3.03

2.15

2.2

1.2

—

Heart failure and hypertrophic cardiomyopathy

3.03

2.15

1.1

1.2

—

Abnormal findings on antenatal screening of mother

181

0.39

2.15

1.4

—

Schizophrenia, schizotypal and delusional disorders

957

0.71

2.15

1.2

1.4

—

Acute bronchiolitis

142

1.78

2.14

1.7

1.6

—

All dysplastic lesions of the cervix uteri, vagina or vulva

107

803

1.33

2.14

1.6

1.3

—

Noninflammatory disorders of female genital tract

169

673

1.27

2.14

1.4

1.3

—

Opening and dilatation of root channel of tooth

159

1.77

2.13

2.1

1.5

—

Faecal incontinence

174

1.73

2.13

1.1

—

Intracranial trauma

245

1520

1.21

2.12

1.3

1.4

—

Parkinson's disease, including avohilmo

333

0.51

2.12

1.1

1.3

—

Congenital malformations of the circulatory system

375

1.48

2.11

1.6

1.5

—

Carcinoma in situ of other and unspecified genital organs

2.59

2.10

1.9

1.1

—

Acute generalized exanthematous pustulosis

102

1.97

2.10

2.1

1.3

—

Dental pulpitis 3

207

1.57

2.10

1.4

—

Selective serotonin reuptake inhibitors

421

1919

1.16

2.10

1.4

—

Morphin

3.23

2.10

1.0

1.2

—

Other and unspecified local infections of skin and subcutaneous tissue

213

1.65

2.09

1.9

1.5

—

Basal cell carcinoma, including avohilmo

190

1214

1.23

2.09

1.3

1.2

—

All-cause Heart Failure

193

1129

1.23

2.09

1.4

1.3

—

Other and unspecified paralytic syndromes

2.94

2.08

1.8

1.3

—

Calcific aortic valvular stenosis, including rheumatic fever

609

1.37

2.08

1.4

1.2

—

Persons encountering health services in circumstances related to reproduction

248

1399

1.20

2.08

1.4

1.5

—

Iron deficiency

2.92

2.07

1.6

1.3

—

Retinal vascular disorders

229

1.62

2.07

1.4

1.3

—

Suppurative otitis media, unspecified

0.00

2.07

0.0

1.2

—

Disorders resulting from impaired renal tubular function

2.04

2.06

2.3

1.4

—

Focal brain injury

146

1.79

2.06

1.7

—

Vulvovaginal ulceration/inflammation in other diseases

117

1.89

2.06

1.1

1.4

—

Malignant neoplasm of ovary

103

1.95

2.05

1.5

1.2

—

Other and unspecified vascular occlusions

176

1.71

2.05

1.5

1.2

—

Other psoriatic arthropathies

277

1.56

2.05

1.3

1.4

—

Other degenerative diseases of the nervous system

588

0.68

2.05

1.3

—

Carcinoma in situ of vulva

4.07

2.05

1.3

1.1

—

Disorders of myoneural junction and muscle in diseases classified elsewhere

4.07

2.05

1.2

1.1

—

Personal history of medical treatment

4.05

2.05

2.8

1.3

—

Benign neoplasm: Appendix

4.05

2.04

2.0

1.1

—

Melanoma in situ of trunk

4.04

2.04

1.0

1.2

—

Stomatitis and related lesions

184

1.69

2.04

1.7

1.2

—

DVT of lower extremities

432

1.44

2.03

1.3

1.2

—

Other misadventures during surgical and medical care

2.42

2.03

1.2

1.4

—

Abnormalities of gait and mobility

262

1.57

2.03

1.5

—

Psoriatic arthropathies, ICD10

286

1.54

2.02

1.3

1.4

—

Congenital malformations of heart and great arteries

339

1.49

2.02

1.4

1.5

—

Personality disorders

102

773

1.32

2.02

1.5

1.4

—

Use of glatiramer acetate

2.66

2.01

1.1

1.5

—

Carcinoma in situ of other and unspecified digestive organs

2.24

2.01

1.4

1.2

—

Other and unspecified injuries of thorax

2.66

2.01

1.8

1.2

—

Carcinoma in situ, bladder

2.24

2.01

1.2

1.4

—

Pedal cyclist injured in transport accident

626

0.65

2.01

1.4

—

Other dorsopathies, not elsewhere classified

428

1965

1.15

2.01

1.5

1.4

—

Fracture of lower leg, including ankle

209

1719

1.21

2.01

1.4

—

Coxarthrosis, primary, with hip surgery

1222

0.76

2.01

1.3

1.2

—

Other abnormal immunological findings in serum

2.83

2.00

1.1

1.7

—

Injuries to the abdomen, lower back, lumbar spine and pelvis

131

1021

1.28

2.00

1.6

1.3

—

Ankylosing spondylitis, ICD10

224

1.61

1.99

1.1

1.5

—

Specific personality disorders

654

1.35

1.99

1.6

1.4

—

Medical abortion

239

1079

1.21

1.99

1.3

—

Diseases of vocal cords and larynx+other diseases of upper respiratory tract, no elsewhere classified

206

1665

1.21

1.99

1.4

—

Other and unspecified disorders involving the immune mechanism, not elsewhere classified

2.16

1.99

1.7

1.5

—

Oral lichen ruber planus

2.30

1.98

1.0

1.2

—

Viral pneumonia (known virus, not influenza)

2.30

1.98

1.8

1.3

—

Colonic or urogenital fistula

101

767

1.32

1.98

1.3

1.4

—

Other and unspecified aplastic anaemias

3.37

1.97

1.1

—

Malignant neoplasm of oral cavity

2.09

1.97

1.1

1.4

—

Recurrent dislocation of patella

119

1.86

1.97

1.3

1.5

—

Juvenile arthritis (FINNGEN)

112

1.88

1.96

1.8

1.5

—

Emotional disorders starting during childhood or adolescence

1.95

1.96

1.7

1.6

—

Viral meningitis

1.99

1.95

1.3

1.5

—

Other and unspecified follicular disorders

1.99

1.95

1.8

1.4

—

Other and unspecified types of non-Hodgkin lymphoma, hilmo

1.99

1.95

1.2

1.4

—

Toxic effect of corrosive substances

4.64

1.95

1.2

1.5

—

Retention of urine

110

714

1.30

1.95

1.4

1.3

—

Scarlet fever

4.61

1.95

1.6

1.1

—

512

1.37

1.95

1.1

1.2

—

Acute drug-induced interstitial lung disorder

3.81

1.94

1.8

1.1

—

Other diseases caused by chlamydiae

3.00

1.94

3.1

1.1

—

Malignant neoplasm of bone and articular cartilage

3.80

1.94

1.0

—

LSIL lesion of the vagina

2.76

1.94

2.6

1.5

—

Complications following infusion, transfusion and therapeutic injection

2.76

1.94

1.2

1.4

—

Vitamin D deficiency

2.59

1.93

2.6

1.1

—

Haemorrhage, not elsewhere classified

2.12

1.92

1.7

1.2

—

Asthma, including avohilmo

484

2480

1.13

1.92

1.3

1.4

—

Pre-eclampsia or eclampsia

650

1.34

1.91

1.3

—

Malignant neoplasm of thyroid gland, excluding all cancers (controls excluding all cancers)

135

1.78

1.91

1.0

1.4

—

Ankylosing spondylitis, strict definition

106

1.90

1.91

1.1

1.6

—

Event of undetermined intent

150

1.74

1.90

1.1

1.5

—

Ankylosing spondylitis

235

1.58

1.89

1.1

1.5

—

Spondylopathies

324

1690

1.17

1.89

1.3

1.4

—

Bipolar affective disorders

498

1.39

1.89

1.4

—

Hydrocephalus

158

0.38

1.88

1.7

1.3

—

Carcinoma in situ of skin of ear and external auricular canal

2.89

1.87

1.0

1.2

—

Benign neoplasm: Skin of upper limb, including shoulder

2.67

1.87

1.8

1.6

—

Melanocytic naevi of scalp and neck

2.66

1.87

1.8

1.6

—

Benign neoplasm of bone and articular cartilage

151

1.73

1.86

1.2

1.5

—

Hypoparathyroidism

2.10

1.86

1.9

1.2

—

Adenocarcinoma and papillary adenocarcinoma of stomach, excluding all cancers (controls excluding all cancers)

2.87

1.86

1.1

1.3

—

Use of levodopa decarboxylase inhibitor

265

0.49

1.86

1.2

—

Malignant neoplasm of tongue

2.41

1.86

1.1

1.3

—

Hypopituitarism

174

1.67

1.86

1.4

1.6

—

Diffuse large B-cell lymphoma

100

1.91

1.85

1.1

1.4

—

Benign neoplasm: Conjunctiva

2.40

1.85

1.5

1.3

—

Benign neoplasm of other and unspecified sites

2.40

1.85

1.0

1.4

—

Other and unspecified injuries of head

144

1.74

1.85

1.2

1.5

—

Leiomyosarcoma

3.59

1.85

1.2

1.1

—

Selective deficiency of immunoglobulin G [IgG] subclasses

3.59

1.85

1.0

1.3

—

Malignant neoplasm of bone and articular cartilage of other and unspecified sites, excluding all cancers (controls excluding all cancers)

3.56

1.84

1.0

1.2

—

Female genital prolapse

567

0.73

1.84

1.3

—

Benign neoplasm: salivary glands, exclude unknown (D119)

190

1.64

1.84

2.1

1.4

—

Diabetic nephropathy

511

1.38

1.84

1.4

1.5

—

Other diseases of oesophagus

190

1.64

1.83

1.5

1.2

—

Lung diseases due to external agents

277

1.52

1.83

1.7

1.3

—

Chronic sinusitis

169

1381

1.22

1.83

1.4

—

Oral leukoplakia and related diseases, including avohilmo

214

1.59

1.82

1.4

—

Rash and other nonspecific skin eruption

254

1.54

1.81

1.6

1.4

—

Benign neoplasm: Parotid gland

168

1.67

1.80

2.2

1.3

—

Personal history of certain other diseases

3.06

1.80

1.0

—

Polyarthritis, unspecified

2.01

1.80

1.3

1.4

—

Oligomenorrhoea

1.96

1.80

1.3

1.1

—

Donors of organs and tissues

2.79

1.80

1.1

1.7

—

COPD, hospital admissions 1, only main diagnosis

110

729

1.29

1.79

1.2

—

Unspecified urinary incontinence

215

1.59

1.79

1.6

1.3

—

Benign neoplasm of eye and adnexa

223

1.57

1.78

1.4

1.3

—

Macular hole

116

1.82

1.78

1.1

1.2

—

Retinal vascular occlusion

223

1.57

1.78

1.4

1.3

—

Kela-code for severe mental illness

1129

0.76

1.78

1.2

1.4

—

Malignant neoplasm of other and unspecified female genital organs, excluding all cancers (controls excluding all cancers)

2.36

1.78

1.0

1.1

—

Other specified/unspecified bacterial intestinal infections

146

1.72

1.77

1.7

1.3

—

Other noninflammatory disorders of vagina

208

1.59

1.76

1.5

1.2

—

Endometriosis of ovary

495

1.37

1.76

1.5

1.3

—

Pericarditis

2.10

1.76

1.6

1.4

—

Other diseases of jaws

154

1.69

1.76

1.5

1.2

—

Carcinoma in situ of vulva

3.38

1.75

1.3

1.1

—

Other bursitis of elbow

3.38

1.75

1.2

—

Obsessive-compulsive disorder

139

1.73

1.75

1.1

1.5

—

Schizophrenia or delusion

955

0.74

1.75

1.2

1.4

—

Retinal detachments and breaks

120

950

1.27

1.75

1.5

1.3

—

Secondary right heart disease

1.99

1.75

1.3

1.2

—

Eosinophilic disease (BM)

2.52

1.74

1.3

1.5

—

Other and unspecified coagulation defects

117

1.80

1.74

1.6

1.4

—

Cerebral palsy and other paralytic syndromes

273

1.51

1.73

1.3

1.5

—

Disorders of porphyrin and bilirubin metabolism

2.95

1.73

1.7

1.3

—

Acute hepatitis B

3.93

1.73

1.4

—

Malignant neoplasm of other and unspecified parts of tongue, excluding all cancers (controls excluding all cancers)

2.68

1.72

1.1

1.3

—

Unstable angina pectoris

857

0.75

1.72

1.2

—

Respiratory insufficiency

147

1.70

1.72

1.2

1.5

—

Renal cell carcinoma of kidney, excluding all cancers (controls excluding all cancers)

2.68

1.72

1.5

1.3

—

Necrobiosis lipoidica, not elsewhere classified

3.91

1.72

1.0

—

Parodontitis, under 40 years and operation codes

178

1.63

1.72

1.6

1.5

—

Parodontitis, operation under 40 years and operation codes

178

1.63

1.72

1.6

1.5

—

Seminoma of testis, excluding all cancers (controls excluding all cancers)

3.88

1.72

1.2

1.9

—

Symptoms and signs involving cognition, perception, emotional state and behaviour

381

2344

1.14

1.71

1.5

1.4

—

Cardiac murmurs and other cardiac sounds

223

1.56

1.71

1.5

1.4

—

Other disorders of conjunctiva

348

1.44

1.70

1.9

1.3

—

Oesophageal obstruction

2.07

1.70

1.1

1.2

—

Dysphagia

491

1.37

1.70

1.2

—

Injuries to unspecified part of trunk, limb or body region

218

1.56

1.70

1.3

1.5

—

Short stature, not elsewhere classified

2.02

1.70

2.2

1.9

—

Pneumococcal septicemia

2.01

1.70

1.5

—

Personal history of malignant neoplasm

1.96

1.70

1.1

1.2

—

Other obstructive and reflux uropathy

1.96

1.69

1.1

1.2

—

Childhood asthma (age<16), excluding more controls

242

1.48

1.69

1.4

—

Rheumatic valve diseases

0.00

1.68

0.0

1.2

—

HSIL lesion of the vulva

2.40

1.68

1.2

1.1

—

Sequelae of external causes of morbidity and mortality

656

1.31

1.68

1.5

1.3

—

Alcohol abuse counselling and surveillance

2.40

1.68

2.0

1.5

—

Benign neoplasm of major salivary glands

219

1.56

1.67

2.1

1.4

—

Fibromyalgia

227

1.55

1.67

1.4

1.3

—

Open wound of ankle and foot

227

1.55

1.67

1.1

1.6

—

Malignant immunoproliferative diseases

3.20

1.67

2.0

1.0

—

Evidence of alcohol involvement determined by level of intoxication

3.19

1.66

1.0

1.1

—

Childhood asthma (age<16)

243

1.47

1.66

1.4

1.5

—

362

1.41

1.66

1.1

1.2

—

Benign neoplasm: Bronchus and lung

3.19

1.66

1.0

1.1

—

Single delivery by forceps and vacuum extractor

286

0.64

1.65

1.2

1.3

—

Bacterial pneumonia (organism specified)

148

1100

1.23

1.65

1.5

1.3

—

Diseases of middle ear and mastoid

212

1465

1.19

1.65

1.5

1.4

—

Etanercept

165

1.64

1.3

1.5

—

Asthma, hospital admissions , main diagnosis only

318

2483

1.15

1.64

1.3

1.4

—

Presbycusis

219

1.55

1.64

1.1

1.2

—

Fracture of foot, except ankle

659

1.31

1.64

1.5

1.4

—

Benign neoplasm: Rectosigmoid junction

2.25

1.63

1.5

1.3

—

KRA_PSY_EATING, excluding more controls

157

1.65

1.63

1.1

1.4

—

Inflammatory disease of uterus

368

1.42

1.63

1.5

1.3

—

Thyroiditis

181

1.61

1.63

1.2

1.4

—

Acute gastritis

150

1.67

1.63

1.6

1.2

—

Abrasion of teeth

495

1.31

1.63

1.6

1.2

—

Motorcycle rider injured in other and unspecified transport accidents

135

1.71

1.62

1.1

1.6

—

Other and unspecified injuries of forearm

3.62

1.62

1.0

1.3

—

Other forms of systemic lupus erythematosus

3.61

1.62

1.0

1.2

—

Hypertension, Pulmonary Arterial

3.61

1.62

1.6

1.1

—

Benign neoplasm: Skin of lip

3.60

1.62

1.0

—

Polycystic ovarian syndrome

1.84

1.61

1.2

1.5

—

Suppurative and unspecified otitis media

130

930

1.24

1.61

1.4

—

Sequelae with surgical and medical care as external cause

505

1.35

1.61

1.5

1.3

—

Speech and linguistic disorders

220

1.53

1.60

1.8

1.5

—

Disorders of conjunctiva

317

2317

1.15

1.60

1.3

1.4

—

Immunodeficiency with predominantly antibody defects

2.01

1.59

1.1

1.5

—

Degenerative macular diseases

238

1.52

1.59

1.8

1.3

—

Coxibs

106

441

1.28

1.59

1.2

1.4

—

Other complications of labour and delivery, not elsewhere classified

253

0.53

1.59

1.0

1.4

—

Kela reimbursement Agammaglobulinemia (D80-84)

3.04

1.59

1.2

1.6

—

Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue

3.04

1.59

1.0

—

Melanocytic naevi of other and unspecified parts of face

136

1.70

1.59

1.2

1.3

—

Diseases of tongue

136

1.70

1.58

1.5

1.2

—

Other prurigo

2.72

1.58

1.1

1.0

—

Infective dermatitis

279

1.47

1.58

1.3

1.4

—

Arterial embolism and thrombosis

106

1.80

1.58

1.6

1.3

—

Type 1 diabetes, wide definition, subgroup 2

2.71

1.58

1.1

1.3

—

Dependence on enabling machines and devices, not elsewhere classified

2.71

1.58

1.3

—

Benign neoplasm: Middle ear, nasal cavity and accessory sinuses

1.83

1.57

1.4

1.3

—

Acute appendicitis, with complications

559

1.33

1.57

1.2

1.4

—

Major coronary heart disease event excluding revascularizations

170

1407

0.83

1.57

1.2

1.3

—

Rheumatoid arthritis, including avohilmo

133

1082

1.23

1.56

1.1

1.3

—

Fracture of shoulder and upper arm

121

974

1.24

1.56

1.6

1.4

—

Other malignant neoplasms of skin (=non-melanoma skin cancer)

173

1138

1.20

1.55

1.3

1.2

—

Unknown and unspecified causes of morbidity

160

1.63

1.55

1.7

1.2

—

Contact with and exposure to communicable diseases

113

900

1.25

1.55

1.4

—

Traumatic subdural haemorrhage

292

1.45

1.54

1.4

1.3

—

Injuries to the head

437

2538

1.12

1.54

1.3

1.4

—

Erythema nodosum

2.04

1.54

1.3

—

Other noninfective disorders of lymphatic vessels and lymph nodes

1.98

1.54

3.1

1.3

—

Other local infections of skin and subcutaneous tissue

232

1.51

1.54

1.9

1.5

—

Dental caries 3, only avohilmo

341

1528

1.14

1.53

1.3

1.4

—

Need for immunization against other single viral diseases

2.29

1.53

1.5

—

Benign neoplasm: Ill-defined sites within the digestive system

3.39

1.53

1.0

1.3

—

Wilms' tumor

3.39

1.53

1.2

1.3

—

Unspecified renal colic

3.38

1.53

1.0

1.3

—

Acute inflammation of orbit

3.38

1.53

1.0

1.1

—

Fibrosarcoma

3.38

1.53

1.0

1.3

—

Pedal cyclist injured in noncollision transport accidents

297

0.57

1.53

1.5

—

Foreign body in alimentary tract

130

1.70

1.53

1.6

1.5

—

Acetic acid derivatives and related substances

106

434

1.27

1.53

1.6

1.4

—

Other/unspecified synovitis and tenosynovitis

298

1.45

1.53

1.3

—

Benign neoplasm: Short bones of lower limb

3.36

1.53

1.0

2.1

—

Cushing syndrome

2.62

1.52

1.1

1.7

—

Lymphangioma, anys site

2.90

1.51

1.3

—

Adhesive capsulitis of shoulder

485

1.34

1.51

1.5

1.3

—

Hypertensive Renal Disease

2.17

1.50

1.5

1.1

—

Melanoma in situ

1.87

1.50

1.3

1.2

—

Congenital malformations of cardiac septa

179

1.57

1.50

1.4

1.6

—

Pneumonia derived septicemia

1.91

1.49

1.5

—

Allergic purpura

1.96

1.49

1.3

1.2

—

Injuries to the ankle and foot

263

2080

1.15

1.48

1.4

—

Corns and callosities

147

1.64

1.47

1.5

1.4

—

Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck

1.81

1.47

1.5

1.4

—

Other diseases of upper respiratory tract

459

2144

1.12

1.47

1.4

—

Congenital malformations of eye, ear, face and neck

166

0.48

1.46

1.5

1.6

—

Rare circulating lymphoid malignancy, excluding all cancers (controls excluding all cancers)

2.23

1.46

1.2

1.5

—

Episodal and paroxysmal disorders

470

2161

1.12

1.46

1.4

—

Benign neoplasm: Tonsil

2.52

1.46

1.1

—

Other protozoal intestinal diseases

2.52

1.45

1.7

1.3

—

Malignant cancer of tonsil and base of tongue, excluding all cancers (controls excluding all cancers)

2.51

1.45

1.3

1.5

—

Rheumatism, unspecified

420

1.36

1.45

1.2

1.3

—

Bacterial pneumoniae

133

966

1.22

1.44

1.5

1.3

—

Aspergillosis

3.16

1.44

1.0

1.3

—

Liposarcoma, excluding all cancers (controls excluding all cancers)

3.16

1.44

1.6

1.3

—

Mantle cell lymphoma, excluding all cancers (controls excluding all cancers)

3.15

1.44

1.2

—

148

1.63

1.44

1.0

1.5

—

Other disorders of skin and subcutaneous tissue, not elsewhere classified

344

1.40

1.44

1.3

1.4

—

Benign neoplasm of meninges

148

1.63

1.44

1.5

1.4

—

Benign neoplasm: Bronchus and lung

2.75

1.44

1.0

1.2

—

Marginal zone B-cell lymphoma, excluding all cancers (controls excluding all cancers)

2.75

1.44

1.0

1.3

—

Adenomyosis (Endometriosis of uterus)

378

1.38

1.43

1.0

1.3

—

Follicular lymphoma

2.04

1.43

1.0

1.3

—

Melanocytic naevi of lower limb, including hip

1.80

1.43

1.5

1.3

—

Mental and behavioural disorders due to sedatives or hypnotics

164

1.59

1.43

1.6

1.5

—

Benign neoplasm of breast

220

1.50

1.43

1.2

1.4

—

Benign neoplasm: Larynx

2.32

1.43

1.2

1.5

—

Other neurological diseases

194

1828

0.85

1.42

1.6

1.3

—

Hypertrophy of breast

499

1.33

1.42

1.2

1.3

—

Cyst of kidney

141

1.64

1.41

1.2

1.3

—

Disorders of muscles

237

1.48

1.41

1.5

1.3

—

Pneumonitis due to solids and liquids

149

1.62

1.41

2.1

1.3

—

Eosinophilia

2.27

1.40

1.3

—

Exposure to other and unspecified inanimate mechanical forces

157

1.60

1.40

1.6

—

Endocrine disorders, other/unspecified

2.26

1.40

1.3

1.5

—

Other and unspecified tonsillitis

120

829

1.23

1.40

1.5

—

Oral leukoplakia and related diseases

126

1.67

1.40

1.1

1.3

—

Postprocedural endocrine and metabolic disorders, not elsewhere classified

304

1.42

1.40

1.3

—

Carcinoma in situ of cervix uteri

173

1.56

1.39

1.6

1.4

—

Poisoning by and exposure to other and unspecified chemicals and noxious substances, undetermined intent

2.43

1.39

1.0

1.7

—

Other abnormal findings in urine

2.43

1.39

1.6

1.1

—

Unspecified mental disorder

104

1286

0.81

1.39

1.3

1.4

—

Tongue abnormality

134

1.65

1.39

1.5

1.3

—

Schizophrenia

458

0.68

1.39

1.1

1.5

—

Burn and corrosion of trunk

1.95

1.38

1.4

—

Internal derangement of knee

145

1205

1.20

1.38

1.3

1.4

—

Burns and corrosions confined to eye and internal organs

2.01

1.38

1.1

1.3

—

Right ventricular outflow tract obstruction

2.64

1.37

1.0

1.8

—

Carcinoma in situ of skin of scalp and neck

2.21

1.37

1.1

—

Diseases of the ear and mastoid process

499

2282

1.11

1.37

1.4

—

Benign neoplasm: Appendix

2.63

1.37

2.0

1.2

—

Migraine without aura, drug-induced

2.63

1.37

1.2

—

Benign neoplasm: Skin of eyelid, including canthus

373

1.37

1.1

1.4

—

Outcome of delivery

307

0.68

1.37

1.1

1.4

—

Other benign neoplasm of uterus: Other parts/unspecified

2.20

1.37

1.0

1.1

—

Malignant neoplasm of base of tongue

2.99

1.36

1.2

—

Other and unspecified hypertrophic disorders of skin

2.98

1.36

2.0

1.0

—

Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs

127

1.66

1.36

1.6

1.5

—

Other injuries of spine and trunk, level unspecified

2.97

1.36

1.0

1.1

—

Cardiomyopathies, Primary/intrinsic

289

1.42

1.36

1.2

1.3

—

Intracerebral haemorrhage

231

1.47

1.36

1.8

1.3

—

Acute and transient psychotic disorders

335

0.63

1.35

1.1

1.4

—

Infections of genitourinary tract in pregnancy

248

0.56

1.35

1.1

1.3

—

Clear cell adenocarcinoma of kidney

1.76

1.35

1.2

1.3

—

Wet age-related macular degeneration

284

1.42

1.35

1.0

1.2

—

Dermatophytosis

298

1.41

1.35

1.3

1.4

—

Car occupant injured in other and unspecified transport accidents

495

1.32

1.35

1.6

1.4

—

Superficial injury of lower leg

662

1.27

1.35

1.4

—

Toxic effects of substances chiefly nonmedicinal as to source

273

1.43

1.34

1.5

—

Open wound of shoulder and upper arm

2.14

1.34

1.2

1.4

—

Acidosis

2.16

1.34

1.4

—

Habitual aborter

2.14

1.34

1.0

1.2

—

Alopecia areata

1.92

1.33

1.2

1.4

—

Open wound of abdomen, lower back and pelvis

1.92

1.33

1.9

1.7

—

Rheumatoid arthritis

120

895

1.22

1.33

1.1

1.4

—

Lesion of lateral popliteal nerve

105

1.72

1.33

1.4

1.6

—

Undetermined asthma, excluding more controls

307

1.40

1.33

1.5

1.3

—

D07AA Corticosteroids, weak (group I)

418

1.34

1.32

1.4

1.5

—

All dysplastic lesions of the cervix uteri

698

1.26

1.32

1.6

1.3

—

Lichen ruber planus, wide definition including periferal and oral lichen planus

567

1.29

1.32

1.3

—

Other and unspecified disorders of skin and subcutaneous tissue

152

1.58

1.31

1.3

—

Migraine without aura

576

1.29

1.31

1.7

1.4

—

Gonococcal infection

1.82

1.31

1.2

1.3

—

Ovarian dysfunction

152

1.58

1.31

1.2

1.4

—

Panniculitis affecting regions of neck and back

1.82

1.31

1.3

1.4

—

Paroxysmal tachycardia

456

1.30

1.31

1.5

1.2

—

Other immunodeficiencies

2.52

1.31

1.2

1.5

—

Malnutrition

2.11

1.30

1.1

1.4

—

Other superficial mycoses

2.11

1.30

2.0

1.6

—

Osteomyelitis

129

1.63

1.30

1.5

—

Somnolence, stupor and coma

1.77

1.29

1.3

1.4

—

Chalazion

301

1.40

1.29

1.1

1.4

—

Carcinoma in situ of skin of upper limb, including shoulder

2.79

1.28

1.4

1.0

—

Reactive arthropathies, FINNGEN

177

1.53

1.28

1.6

1.5

—

Small fibre neuropathy

1.95

1.28

1.7

1.4

—

Campylobacter enteritis

1.95

1.28

1.9

1.4

—

Viral agents as the cause of diseases classified to other chapters

2.01

1.27

1.5

1.6

—

Pregnancy with abortive outcome

239

1086

1.15

1.27

1.3

—

Keratoconus

2.01

1.27

2.0

1.5

—

Hyperhidrosis

2.01

1.27

1.2

—

Chronic iridocyclitis

122

1.65

1.27

1.6

1.4

—

Other acute skin changes due to ultraviolet radiation

1.79

1.27

1.2

1.4

—

Idiopathic urticaria

2.06

1.27

1.2

1.1

—

COPD, hospital admissions 3, with asthma pneumonia sepsis

514

1.28

1.26

1.2

—

False labour

585

0.78

1.26

1.2

1.3

—

Generalized anxiety disorder

362

1.36

1.26

1.8

1.4

—

Any mental disorder, or suicide (or attempt), or psychic disorders complicating pregnancy, partum or puerperum or nerve system disorders, excluding more controls

767

1.24

1.26

1.4

—

Cardiomyopathy, other and unspecified

170

1.53

1.25

1.1

1.4

—

Mixed hyperlipidaemia

1.83

1.25

1.1

1.3

—

Crowding of teeth, including avohilmo

173

1.48

1.25

1.7

1.5

—

Unspecified acute lower respiratory infection

354

1.36

1.25

1.2

1.5

—

Osteonecrosis due to drugs

2.42

1.25

1.3

1.2

—

Tonsillectomy and adenotomy

168

1370

0.85

1.24

1.5

1.4

—

2.01

1.23

1.0

1.2

—

Acute lymphadenitis

147

1.57

1.23

1.2

1.6

—

Prurigo nodularis

1.98

1.22

1.0

1.4

—

Nonsuppurative otitis media

533

1.27

1.22

1.6

1.4

—

Other and unspecified pemphigoid

2.66

1.22

1.2

1.0

—

Disturbance of activity and attention

234

1.44

1.22

1.7

1.6

—

Achalasia of cardia

2.18

1.21

1.3

1.1

—

Other hearing loss

634

1.26

1.21

1.3

1.2

—

Abdominal aortic aneurysm (AAA)

178

1.51

1.21

1.1

1.3

—

Malignant neoplasm of bladder

116

1.64

1.21

1.4

1.3

—

Injury of muscle and tendon at hip and thigh level

239

0.58

1.21

1.7

1.4

—

Reactive arthropathies

238

1.43

1.20

1.6

1.4

—

Pilonidal cyst

205

1.47

1.19

1.4

1.6

—

Extrapyramidal and movement disorders

997

0.80

1.19

1.3

—

Serous carcinoma of ovary

1.75

1.19

1.3

1.2

—

Measles

2.33

1.19

1.0

1.2

—

Cauda equina syndrome

2.32

1.19

1.3

—

Shoulder region

2.32

1.19

1.0

1.3

—

Pre-eclampsia

603

1.26

1.19

1.3

—

Emotionally unstable personality disorder

306

1.38

1.19

1.4

1.5

—

Benign neoplasm: Other/unspecified site

2.12

1.19

1.0

1.2

—

Thyroiditis, unspecified

2.12

1.19

1.1

1.4

—

Cardiomyopathy, Hypertrophic obstructive

2.12

1.18

1.1

1.3

—

Other and unspecified acute skin changes due to ultraviolet radiation

1.89

1.18

1.3

—

Peripheral artery operations in Hilmo

247

1.42

1.18

1.3

—

Postpartum care and examination

253

0.68

1.17

1.1

1.4

—

Carrier of infectious disease

1.94

1.17

2.0

1.4

—

Exposure to other specified factors

277

2308

1.13

1.17

1.3

1.4

—

Chronic Coagulation defects

1.94

1.17

1.5

1.4

—

Benign neoplasm: Long bones of lower limb

1.94

1.17

1.1

1.5

—

Glaucoma, exfoliation

186

0.54

1.17

1.0

1.2

—

Benign neoplasm: Other and unspecified parts of mouth

2.01

1.16

1.1

1.3

—

Dental pulpitis 3, only avohilmo

198

1.40

1.16

1.3

1.5

—

Other and unspecified iridocyclitis

102

1.67

1.16

1.4

—

Malignant neoplasm of oropharynx

0.00

1.16

0.0

1.4

—

Acute appendicitis, no complications

209

1821

1.15

1.16

1.4

—

malignant neoplasm of female genital organs

359

1.34

1.16

1.3

1.2

—

Malignant neoplasm of testis

2.06

1.15

1.1

1.7

—

Dissocial personality disorder

2.06

1.15

2.3

1.7

—

Cerebral palsy

2.06

1.15

1.4

2.0

—

LSIL lesion of the cervix uteri, vagina or vulva

368

1.33

1.15

1.6

1.3

—

Atypical virus infections of central nervous system

2.52

1.15

1.2

1.4

—

Later onset COPD

453

1.27

1.15

1.1

1.2

—

Major coronary heart disease event

199

1524

0.87

1.15

1.3

1.4

—

Pleural plaque

166

1.51

1.14

1.2

1.3

—

Blepharochalasis

780

0.78

1.14

1.4

1.3

—

Amputation of toe

126

1.59

1.14

1.4

1.3

—

Other inflammation of eyelid

343

1.34

1.14

1.3

1.4

—

Assault by bodily force

175

1.49

1.12

1.2

1.6

—

Oral lichen ruber planus, hypothyreosis or thyroxin

2.01

1.12

1.0

1.1

—

Disturbances of skin sensation

788

1.22

1.12

1.3

1.4

—

Coxarthrosis [arthrosis of hip](FG)

146

1237

0.85

1.12

1.3

—

Myositis

1.91

1.12

1.5

1.3

—

Heart failure and coronary heart disease

573

0.78

1.12

1.3

1.2

—

Malignant neoplasm of head and neck

167

1.50

1.12

1.0

1.4

—

Undetermined asthma

318

1.35

1.12

1.5

1.3

—

Open wound of forearm

200

1.45

1.12

1.9

1.5

—

Alcohol-induced chronic pancreatitis

159

1.51

1.12

1.5

1.6

—

Benign neoplasm: Pituitary gland, craniopharyngeal duct

119

1.60

1.11

1.7

1.4

—

Cardiomyopathy (excluding other)

310

1.36

1.11

1.2

1.3

—

Dental caries 1 and operation codes, only avohilmo

115

479

1.21

1.11

1.3

1.8

—

Obstructed labour due to maternal pelvic abnormality

493

0.73

1.11

1.7

1.3

—

Primary coxarthrosis, bilateral

731

0.78

1.10

1.2

—

Dysplasia of cervi uteri

553

1.23

1.10

1.6

1.3

—

Benign neoplasm: Skin of trunk

1.67

1.10

1.2

1.4

—

Prolonged pregnancy

365

0.70

1.10

1.0

1.3

—

Bacterial sepsis of newborn

2.41

1.09

2.0

2.3

—

Unspecified parasitic disease

2.40

1.09

2.2

1.4

—

Dental caries 3 and operation codes, only avohilmo

131

553

1.19

1.09

1.4

1.8

—

Alcohol induced polyneuropathy

2.40

1.09

2.4

1.3

—

Vitiligo

2.40

1.09

1.4

1.0

—

Other congenital malformations of peripheral vascular system

2.39

1.09

1.6

1.9

—

Fenamates

278

1.31

1.09

1.6

1.4

—

Chronic tubulo-interstitial nephritis

1.73

1.09

1.4

1.2

—

Benign neoplasm: Tongue

1.96

1.09

1.4

1.3

—

1.83

1.08

2.1

2.0

—

Fall on and from stairs and steps

665

1.23

1.08

1.5

1.4

—

Mouth breathing

149

1277

1.17

1.08

1.4

—

Cardiodefibrillation

112

936

1.20

1.08

1.3

—

Disorders of breast

172

1382

1.15

1.08

1.3

—

Seropositive rheumatoid arthritis

682

1.23

1.07

1.1

1.3

—

Migraine without aura and triptan purchases

443

1.29

1.07

1.7

1.4

—

Heterophoria

205

0.58

1.06

1.5

—

Infections specific to the perinatal period

2.14

1.06

2.0

—

Preparation and fitting of bite rail to mouth

373

0.70

1.06

1.9

1.4

—

Bacterial, viral and other infectious agents

211

1.43

1.06

1.6

—

Recurring oral aphthae

113

1.60

1.05

1.9

1.3

—

Pre-eclampsia or poor fetal growth

106

883

1.20

1.05

1.4

1.3

—

Osteonecrosis

129

1.56

1.05

1.4

1.3

—

Developmental endpoint to exclude non autoimmune-cases from E4_HYTHY_AI_STRICT

115

968

1.19

1.05

1.3

1.4

—

Septal defects

174

1.47

1.05

1.5

1.6

—

Cholesteatoma of middle ear

121

0.49

1.05

1.0

1.4

—

Varicose veins

209

1389

1.14

1.04

1.2

—

Intracranial injury

200

1698

1.14

1.04

1.3

1.4

—

ICD-8 DM (Sub-endpoint used for defining DM endpoints)

1.67

1.04

1.2

1.4

—

Pustulosis palmaris et plantaris

1.67

1.04

1.2

1.3

—

Other menopausal disorders

548

0.81

1.04

1.2

1.3

—

Respiratory conditions due to other external agents

1.97

1.04

1.6

1.1

—

Postdysenteric arthropathy

2.29

1.03

1.0

1.3

—

Galactorrhea

2.29

1.03

1.2

1.6

—

Carcinoma in situ of colon

2.29

1.03

1.0

1.5

—

Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified

149

0.54

1.03

1.0

1.2

—

Other specified/unspecified soft tissue disorders

1.64

1.03

1.5

1.2

—

Schizoaffective disorder

203

0.59

1.03

1.1

1.5

—

Melanocytic naevi of upper limb, including shoulder

2.07

1.03

1.0

1.2

—

Benign neoplasm of thyroid gland

1.74

1.03

1.1

1.2

—

Pyogenic arthritis

138

1.53

1.02

1.4

—

Benign neoplasm: Cerebral meninges

138

1.52

1.02

1.4

—

Transient global amnesia

215

0.60

1.02

1.4

1.3

—

Aortic valve malfunction, age under 60 years

238

1.39

1.02

1.8

1.5

—

Dental caries 1, only avohilmo

314

1445

1.11

1.02

1.3

1.4

—

Correction of physiology of bite - demanding therapy visit

177

0.56

1.01

2.6

1.4

—

Polyuria

554

1.25

1.01

1.8

1.3

—

Diffuse brain injury

1.69

1.01

1.5

1.7

—

Other puerperal infections

177

0.56

1.01

1.0

1.4

—

Mixed specific developmental disorders

1.74

1.01

1.5

1.8

—

Benign neoplasm: Skin of upper limb, including shoulder

1.89

1.00

1.8

1.3

—

Other specific arthropathies, wide

1.88

1.00

1.1

—

Peripheral artery disease

131

900

1.17

1.00

1.2

—

Lateral epicondylitis

415

0.72

1.00

1.7

1.4

—

Malignant neoplasm of larynx

2.01

1.00

1.0

1.1

—

222

1.40

1.00

1.2

1.4

—

2.01

1.00

1.6

1.1

—

Complications of labour and delivery

189

1201

0.88

1.00

1.4

1.3

—

Cholera

107

1.60

0.99

1.3

1.2

—

Other specified/unspecified inflammatory spondylopathies

123

1.55

0.99

1.1

1.3

—

Maltreatment syndromes

123

1.55

0.99

1.0

1.5

—

Convalescence

115

1.57

0.99

1.4

1.5

—

Synovial cyst of popliteal space [Baker]

164

1.47

0.99

1.2

1.3

—

Injuries to the shoulder and upper arm

306

2319

1.11

0.99

1.4

—

Burn and corrosion of shoulder and upper limb, except wrist and hand

1.85

0.99

1.1

1.4

—

Erythema multiforme

1.85

0.98

2.3

1.4

—

Arterial embolism and thrombosis of lower extremity artery

1.81

0.98

1.2

—

Persistent mood disorders

521

1.25

0.98

1.8

1.3

—

Temporomandibular joint disorders

379

1.29

0.97

1.5

1.3

—

Statin medication

299

1511

1.11

0.97

1.5

1.4

—

Congenital malformations of uterus and cervix

1.95

0.97

1.1

1.6

—

Hallux valgus (acquired)

775

0.83

0.97

1.1

1.4

—

Benign neoplasm: Choroid

132

1.52

0.97

1.4

1.3

—

Burn and corrosion confined to eye and adnexa

1.86

0.97

1.1

1.4

—

Disorders of vitreous body and globe

169

1442

1.14

0.96

1.3

—

Hypersomnia

0.00

0.96

0.0

1.6

—

HSIL lesion of the cervix uteri, vagina or vulva

540

1.24

0.96

1.6

1.4

—

Suppurative and necrotic conditions of lower respiratory tract

108

1.58

0.96

1.4

1.5

—

Papillary adenocarcinoma of thyroid gland, excluding all cancers (controls excluding all cancers)

116

1.56

0.96

1.1

1.4

—

Other shoulder lesions

241

1.37

0.96

1.5

1.3

—

Left ventricular outflow tract obstruction (LVOTO), broad definition

267

1.35

0.96

1.7

1.5

—

Injuries to the elbow and forearm

248

2009

1.12

0.95

1.5

1.3

—

Sensorineural hearing loss

223

1751

0.89

0.95

1.3

1.4

—

Iliotibial band syndrome

0.00

0.95

0.0

1.5

—

Benign neoplasm: Vagina

0.00

0.95

0.0

1.1

—

Other disorders of eye and adnexa

363

1.30

0.95

1.3

1.4

—

Other degenerative diseases of the basal ganglia

0.00

0.95

0.0

1.0

—

Covid-19 suspected case

559

1.24

0.95

1.6

1.5

—

Juvenile rheumatoid arthirtis

1.77

0.94

1.7

1.6

—

Other vitreous opacities

1.65

0.94

1.5

1.3

—

Carcinoma in situ of skin of lower limb, including hip

1.90

0.94

1.1

1.0

—

Benign neoplasm: other/unspecified salivary gland

1.90

0.94

1.6

1.3

—

≡ Risteys

FG R12 + FR

FinnGen R11 + FinRegistry

FinnGen R10 + FinRegistry

FinnGen R10

FinnGen R9

FinnGen R8

FinnGen R7

FinnGen R6

FinnGen R5

FinnGen R4

FinnGen R3

Liver Pathology biopsy report

Coding

Definition

OMOP mapping QC

Cohort

Year of birth distribution

Age at first measurement

Age at last measurement

Age at start of registry

Duration from first to last measurement

Statistics

Number of measurements over the years

Number of measurements per person

Distribution of lab values

Value range per person

LabWAS