Pneumococcal septicemia

PNEUMO_SEPTHICHE

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 A40.3
  • Hospital discharge: ICD-9 0382
  • Hospital discharge: ICD-8 0382
  • Cause of death: ICD-10 A40.3
  • Cause of death: ICD-9 0382
  • Cause of death: ICD-8 0382

2 out of 7 registries used, show all original rules.

1308

4. Check minimum number of events

None

1308

5. Include endpoints

None

1308

6. Filter based on genotype QC (FinnGen only)

1252

Control definitions (FinnGen only)

Control exclude
ASTHMA_SEPTICHE_PNEUMONIA

Extra metadata

First used in FinnGen datafreeze
DF2
Parent code in ICD-10
A40
Name in latin
Septic(h)aemia pneumococcica

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 14540 6399 8046
Only index persons 12041 5409 6632
Unadjusted period prevalence (%)
Whole population 0.21 0.18 0.22
Only index persons 0.23 0.20 0.25
Median age at first event (years)
Whole population 40.52 39.46 41.06
Only index persons 36.59 36.71 36.49

-FinnGen-

Key figures

All Female Male
Number of individuals 1252 572 680
Unadjusted period prevalence (%) 0.26 0.20 0.31
Median age at first event (years) 59.03 54.61 62.76

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1308
Matched controls
13080
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
J13
ICD-10 Finland
Pneumonia due to Streptococcus pneumoniae
241.6
307.7
477
31
J18.9
ICD-10 Finland
Pneumonia, unspecified
8.5
307.7
835
2255
A40.3
ICD-10 Finland
Sepsis due to Streptococcus pneumoniae
+∞
307.7
1148
*
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
7.4
206.6
363
647
0382A
ICD-9 Finland
Septicaemia, Pneumococcal septicaemia
+∞
120.7
114
*
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.9
104.5
401
1322
J01MA14
ATC
moxifloxacin; systemic
5.1
102.4
244
558
A41.9
ICD-10 Finland
Sepsis, unspecified
7.6
99.2
149
217
J86.9
ICD-10 Finland
Pyothorax without fistula
17.9
89.1
73
43
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.0
81.7
778
4290
A49.9
ICD-10 Finland
Bacterial infection, unspecified
3.8
72.3
266
833
J01MA12
ATC
levofloxacin; systemic
3.1
68.7
369
1460
J18.1
ICD-10 Finland
Lobar pneumonia, unspecified
13.2
64.4
62
49
R50.9
ICD-10 Finland
Fever, unspecified
2.9
51.3
303
1242
03820
ICD-8 Finland
Septicaemia, Pneumococcal
+∞
48.2
46
*
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
4.4
47.4
128
317
R81
ICPC
Pneumonia
5.3
47.1
100
203
C90.0
ICD-10 Finland
Multiple myeloma
10.8
43.9
48
46
R03AK06
ATC
salmeterol and fluticasone; inhalant
2.8
43.0
263
1089
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.6
41.9
306
1384
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
3.0
41.4
208
774
TPH04
NOMESCO Finland
Cathetrisation of vein
2.4
41.2
366
1810
H02AB06
ATC
prednisolone; systemic
2.2
40.3
674
4313
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
3.0
39.8
202
755
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
4.2
39.5
111
283
R03BB04
ATC
tiotropium bromide; inhalant
2.9
38.7
201
760
G00.1
ICD-10 Finland
Pneumococcal meningitis
388.3
38.2
38
*
WX872
NOMESCO Finland
Intensive care
3.9
37.1
116
319
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
4.3
37.0
99
243
WX892
NOMESCO Finland
Monitored bed care
3.2
35.6
155
529
9732/3-C42.1
ICD-O-3
Plasma cell myeloma of bone marrow
11.5
34.6
36
32
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.6
34.0
235
1026
TPH07
NOMESCO Finland
Cathetrisation of artery
2.7
33.6
202
823
C03CA01
ATC
furosemide; systemic
2.1
33.4
457
2660
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
2.3
32.9
311
1562
N17.9
ICD-10 Finland
Acute renal failure, unspecified
4.0
31.5
92
241
J45.9
ICD-10 Finland
Asthma, unspecified
2.3
30.7
287
1430
GD1AD
NOMESCO Finland
Thorax CT examination
3.4
30.7
115
357
A41.8
ICD-10 Finland
Other specified sepsis
5.7
30.6
58
106
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
3.8
29.9
95
264
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.9
29.6
722
5086
J01FF01
ATC
clindamycin; systemic
2.1
28.9
388
2222
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
3.3
26.5
104
332
GA1AE
NOMESCO Finland
Ultrasound examination of thorax
5.1
26.2
56
114
ZX120
NOMESCO Finland
Intravenous
2.6
25.4
155
632
TK800
NOMESCO Finland
Hemodialysis
5.2
25.3
53
106
A46
ICD-10 Finland
Erysipelas
2.3
25.3
224
1084
J44.9
ICD-10 Finland
Chronic obstructive pulmonary disease, unspecified
3.4
25.1
96
301
XW000
NOMESCO Finland
Bone marrow biopsy
3.6
24.4
84
246
R03AC02
ATC
salbutamol; inhalant
1.8
24.1
724
5310
R03AL01
ATC
fenoterol and ipratropium bromide; inhalant
4.1
23.9
67
170
ZXD05
NOMESCO Finland
Urgent procedure
1.9
23.4
427
2682
J45.1
ICD-10 Finland
Nonallergic asthma
2.8
23.1
126
485
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
2.9
22.8
112
407
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.8
22.8
122
465
R4110
NOMESCO Finland
Physiotherapy
1.9
22.7
382
2333
I50.9
ICD-10 Finland
Heart failure, unspecified
2.2
22.5
227
1154
J44.1
ICD-10 Finland
Chronic obstructive pulmonary disease with acute exacerbation, unspecified
3.8
22.4
71
197
WX730
NOMESCO Finland
Conventional respirator
6.2
22.1
38
63
UGC12
NOMESCO Finland
Flexible bronchoscopy
2.6
21.3
127
511
I50.0
ICD-10 Finland
Congestive heart failure
2.6
20.9
127
516
J01CA04
ATC
amoxicillin; systemic
2.0
20.8
1073
9077
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
3.8
20.8
64
174
S97
ICPC
Chronic ulcer skin
2.8
20.7
106
394
GAA10
NOMESCO Finland
Intercostal insertion of pleural drainage tube
4.9
20.5
45
94
G00.9
ICD-10 Finland
Bacterial meningitis, unspecified
48.8
20.2
24
5
XF400
NOMESCO Finland
ECG with 12 standard connections
2.0
20.2
239
1289
GA4AT
NOMESCO Finland
Cathetrisation of pleural cavity with ultrasound guidance
6.4
19.8
33
53
J96.1
ICD-10 Finland
Chronic respiratory failure
4.4
19.6
49
114
R96
ICPC
Asthma
2.4
19.3
139
612
R03DA04
ATC
theophylline; systemic, rectal
2.9
19.2
93
335
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
2.3
19.0
152
701
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.9
18.9
262
1491
WW200
NOMESCO Finland
Immunization
4.0
18.8
53
135
4810A
ICD-9 Finland
Pneumococcal pneumonia[PNEUMONIA PNEUMOCOCCICA]
39.0
18.6
23
6
EBA15
NOMESCO Finland
Extraction of multiple teeth
3.3
18.4
71
224
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.0
18.2
233
1288
J01DB01
ATC
cefalexin; oral
1.9
18.2
1057
9021
R95
ICPC
Chron obstructive pulmonary disease
3.8
18.2
57
157
J10.0
ICD-10 Finland
Influenza with pneumonia, seasonal influenza virus identified
6.4
18.1
30
48
A02BC02
ATC
pantoprazole; systemic
1.7
17.6
825
6589
TKC20
NOMESCO Finland
Catheterisation of bladder
2.5
17.5
113
472
GA4YT
NOMESCO Finland
Puncture of pleura with ultrasound guidance
3.4
17.4
64
196
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
3.3
17.3
66
207
H02AB09
ATC
hydrocortisone; systemic
4.0
17.2
49
126
153
Kela drug reimbursment
Lenalidomid
13.5
17.0
29
22
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
2.5
16.9
111
468
L03AA02
ATC
filgrastim; parenteral
3.7
16.8
54
151
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
2.8
16.8
88
331
H02AB07
ATC
prednisone; oral
2.0
16.6
188
993
WX882
NOMESCO Finland
High dependency care
3.3
16.6
64
202
L04AA01
ATC
[U] ciclosporin
6.0
16.6
29
49
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
3.6
16.5
55
158
M04AA01
ATC
allopurinol; systemic
2.0
16.5
192
1025
N17.8
ICD-10 Finland
Other acute renal failure
6.2
16.4
28
46
TDM10
NOMESCO Finland
Puncture of maxillary antrum
3.3
16.2
63
200
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
2.6
16.1
100
410
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.7
15.7
393
2650
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.7
15.6
363
2400
L04AX04
ATC
lenalidomide; oral
11.9
15.6
28
24
H02AB04
ATC
methylprednisolone; systemic
2.0
15.5
186
1001
J15.4
ICD-10 Finland
Pneumonia due to other streptococci
161.9
15.5
16
*
R02
ICPC
Shortness of breath/dyspnoea
2.0
15.5
180
959
Z3226
NOMESCO Finland
Physiotherapist
1.8
15.5
249
1479
WX722
NOMESCO Finland
PEEP
2.8
15.4
79
294
J46
ICD-10 Finland
Status asthmaticus
3.9
15.4
45
118
Z3231
NOMESCO Finland
Registered nurse
1.7
14.8
364
2438
JN4AD
NOMESCO Finland
Body CT examination
2.2
14.7
139
685
AA1AD
NOMESCO Finland
CT of head and brain
1.7
14.7
346
2291
120
Kela drug reimbursment
Hypogammaglobulinaemia
36.5
14.5
18
5
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
2.9
14.4
70
253
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
3.6
14.1
46
130
B18.2
ICD-10 Finland
Chronic viral hepatitis C
5.2
14.1
29
57
N05BA01
ATC
diazepam; systemic, rectal
2.0
14.1
172
930
Z72.0
ICD-10 Finland
Tobacco use
3.6
14.1
47
135
SPAT1255
SPAT
Intravenous administration of medicine
2.4
14.1
98
424
N02AX02
ATC
tramadol; systemic, rectal
1.6
14.0
520
3844
R05
ICPC
Cough
1.7
14.0
303
1958
L04AA06
ATC
mycophenolic acid; systemic
4.3
13.9
36
86
A03
ICPC
Fever
1.8
13.9
231
1381
D80.1
ICD-10 Finland
Nonfamilial hypogammaglobulinaemia
20.3
13.8
20
10
J45.0
ICD-10 Finland
Predominantly allergic asthma
2.2
13.7
124
600
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.2
13.6
124
601
R03BA05
ATC
fluticasone; inhalant
1.8
13.4
238
1451
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
2.3
13.4
110
512
J06BA01
ATC
immunoglobulins, normal human, for extravascular adm.; systemic
40.5
13.2
16
*
J45
ICD-10 Finland
Asthma
2.1
13.1
127
632
A28
ICPC
Limited function/disability NOS
1.8
13.0
225
1360
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.9
13.0
177
994
R06.0
ICD-10 Finland
Dyspnoea
1.6
12.9
341
2314
J96.0
ICD-10 Finland
Acute respiratory failure
4.8
12.9
29
62
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
2.3
12.9
99
448
WX725
NOMESCO Finland
Noninvasive ventilation
2.5
12.8
82
341
A07AA02
ATC
nystatin; oral
2.5
12.8
80
329
127
Kela drug reimbursment
Transplant complication
4.3
12.7
33
79
WW500
NOMESCO Finland
Blood transfusion
2.8
12.7
66
247
R56.8
ICD-10 Finland
Other and unspecified convulsions
2.5
12.7
81
336
JN4BD
NOMESCO Finland
Extensive body CT
2.0
12.7
140
730
SPAT1254
SPAT
Administration of medicine
1.8
12.7
213
1276
Z2221
NOMESCO Finland
Medical doctor
1.6
12.7
338
2298
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.9
12.6
180
1025
SPAT1262
SPAT
Handing over of treatment supplies
1.8
12.5
224
1368
D64.9
ICD-10 Finland
Anaemia, unspecified
2.0
12.4
147
786
D47.2
ICD-10 Finland
Monoclonal gammopathy of undetermined significance (MGUS)
4.9
12.4
27
56
GBB00
NOMESCO Finland
Tracheostomy
5.2
12.2
25
49
3820A
ICD-9 Finland
Suppurative and unspecified otitis media, Acute suppurative otitis media
5.0
12.2
26
53
C07AB07
ATC
bisoprolol; oral
1.5
12.2
586
4550
I48
ICD-10 Finland
Atrial fibrillation and flutter
1.7
12.1
286
1882
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.0
12.1
142
758
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
2.1
12.0
119
596
WZC00
NOMESCO Finland
Treatment plan or consultation
1.6
12.0
443
3244
ZXE00
NOMESCO Finland
One hour or less
1.5
12.0
474
3525
Z49.1
ICD-10 Finland
Extracorporeal dialysis
4.9
11.9
26
54
R03AC12
ATC
salmeterol; inhalant
2.6
11.9
69
274
B01AB05
ATC
enoxaparin; parenteral
1.6
11.7
370
2613
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
4.2
11.6
30
72
J09
ICD-10 Finland
Influenza due to identified zoonotic or pandemic influenza virus
3.1
11.5
48
159
C03DA01
ATC
spironolactone; oral
1.9
11.5
160
902
Z2446
NOMESCO Finland
Social worker
2.1
11.5
106
516
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.7
11.5
236
1496
B01AA03
ATC
warfarin; systemic
1.7
11.4
250
1610
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.7
11.4
271
1784
TK810
NOMESCO Finland
Hemofiltration
9.0
11.3
23
26
WX408
NOMESCO Finland
General anesthesy, balanced
1.6
11.3
326
2252
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
2.3
11.3
86
388
R06AE07
ATC
cetirizine; oral
1.5
11.2
505
3849
B99
ICD-10 Finland
Other and unspecified infectious diseases
3.4
11.2
39
116
A40.9
ICD-10 Finland
Streptococcal sepsis, unspecified
20.2
11.1
16
8
M10.9
ICD-10 Finland
Gout, unspecified
2.2
11.1
98
469
R03AK10
ATC
vilanterol and fluticasone furoate; inhalant
2.6
11.1
67
271
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
2.3
10.9
82
368
R03BA02
ATC
budesonide; inhalant
1.7
10.8
218
1373
J20
ICD-10 Finland
Acute bronchitis
2.0
10.6
125
667
J01CE02
ATC
phenoxymethylpenicillin; oral
1.5
10.5
824
6978
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
2.7
10.5
54
202
D65
ICD-10 Finland
Disseminated intravascular coagulation [defibrination syndrome]
32.8
10.3
13
*
B03XA01
ATC
erythropoietin; parenteral
5.2
10.3
21
41
R70.0
ICD-10 Finland
Elevated erythrocyte sedimentation rate
3.3
10.3
38
117
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
3.7
10.3
32
88
L04AD01
ATC
ciclosporin; systemic
3.6
10.2
33
93
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.5
10.2
570
4508
J84.9
ICD-10 Finland
Interstitial pulmonary disease, unspecified
3.5
10.2
35
103
J01FA06
ATC
roxithromycin; oral
1.5
10.1
444
3346
N03AX16
ATC
[U] pregabalin
1.6
10.1
262
1758
NJ3DA
NOMESCO Finland
Long bones of extremities X-ray examination
9.2
10.0
20
22
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
2.3
10.0
78
355
R03DC03
ATC
montelukast; oral
1.7
9.8
189
1174
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
2.3
9.8
75
339
J22
ICD-10 Finland
Unspecified acute lower respiratory infection
2.2
9.8
80
372
4859X
ICD-9 Finland
Bronchopneumonia, organism unspecified[PNEUMONIA NUD]
3.4
9.8
35
106
N03AG01
ATC
valproic acid; systemic, rectal
2.2
9.7
81
379
L04AX01
ATC
azathioprine; systemic
2.6
9.7
57
228
I83.0
ICD-10 Finland
Varicose veins of lower extremities with ulcer
3.3
9.6
36
112
WX704
NOMESCO Finland
Intubation
2.0
9.6
102
525
6BA02, ,
NOMESCO Finland
15.2
9.5
15
10
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
2.1
9.5
87
423
R03AL09
ATC
formoterol, glycopyrronium bromide and beclometasone; inhalant
3.0
9.5
42
145
R03AK07
ATC
formoterol and budesonide; inhalant
1.6
9.4
233
1544
J84.8
ICD-10 Finland
Other specified interstitial pulmonary diseases
4.4
9.4
23
53
A40.8
ICD-10 Finland
Other streptococcal sepsis
4.9
9.3
20
41
GD1CD
NOMESCO Finland
Thorax extensive CT-examination
4.9
9.3
20
41
M00.9
ICD-10 Finland
Pyogenic arthritis, unspecified
4.5
9.3
22
49
N18.0
ICD-10 Finland
End-stage renal disease
4.5
9.3
22
49
J01DA01
ATC
[U] cefalexin
1.4
9.2
716
5982
SPAT1263
SPAT
Sampling
1.4
9.1
503
3946
ZX108
NOMESCO Finland
Inhalation
5.1
9.1
19
38
A04AA01
ATC
ondansetron; systemic, rectal
2.0
9.1
98
507
M05BA04
ATC
alendronic acid; oral
2.0
9.0
98
508
B34.9
ICD-10 Finland
Viral infection, unspecified
2.7
9.0
47
177
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
2.4
9.0
59
249
H66.0
ICD-10 Finland
Acute suppurative otitis media
1.9
9.0
111
602
TQW11
NOMESCO Finland
Vacuum treatment of wound
3.2
9.0
35
112
GAC97
NOMESCO Finland
Other endoscopic operation on pleura
18.7
8.9
13
7
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.5
8.9
286
2010
J45.8
ICD-10 Finland
Mixed asthma
2.9
8.9
42
150
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
3.0
8.8
38
129
N05AA02
ATC
levomepromazine; systemic
2.5
8.8
54
221
E000001, ,
ATC
1.6
8.8
239
1618
ZXE10
NOMESCO Finland
More than one and less than three hours
1.5
8.8
415
3157
A02BC01
ATC
omeprazole; systemic
1.5
8.7
314
2263
R03AL06
ATC
olodaterol and tiotropium bromide; inhalant
3.3
8.7
32
99
J18.0
ICD-10 Finland
Bronchopneumonia, unspecified
4.0
8.6
24
61
A06AD11
ATC
lactulose; oral
1.7
8.6
180
1141
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.4
8.6
496
3913
N05CF01
ATC
zopiclone; oral
1.5
8.6
363
2701
A12AA04
ATC
calcium carbonate; oral
3.6
8.5
28
80
L01AA01
ATC
cyclophosphamide; systemic
10.1
8.5
16
16
NA2AA
NOMESCO Finland
Thoracal spine X-ray examination without contrast
2.9
8.5
40
143
ZX112
NOMESCO Finland
Subcutaneous
3.1
8.5
35
116
R03BA01
ATC
beclometasone; inhalant
1.7
8.4
155
949
M00.1
ICD-10 Finland
Pneumococcal arthritis and polyarthritis
90.6
8.4
9
*
I48.9
ICD-10 Finland
Atrial fibrillation and atrial flutter, unspecified
2.1
8.4
84
423
N02BE01
ATC
paracetamol; systemic, rectal
1.6
8.4
1078
9818
A40.0
ICD-10 Finland
Sepsis due to streptococcus, group A
12.8
8.4
14
11
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
1.8
8.4
118
668
J47
ICD-10 Finland
Bronchiectasis
3.4
8.4
30
91
B03XA02
ATC
darbepoetin alfa; parenteral
3.0
8.4
35
117
R11
ICD-10 Finland
Nausea and vomiting
1.9
8.3
111
619
V03AE01
ATC
polystyrene sulfonate; oral
3.9
8.3
24
63
J01AA02
ATC
doxycycline; systemic
1.4
8.3
880
7710
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
2.4
8.2
56
241
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
2.7
8.2
42
157
N07BB01
ATC
disulfiram; oral
2.4
8.2
55
235
R03AL02
ATC
salbutamol and ipratropium bromide; inhalant
4.4
8.2
20
46
L02.4
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of limb
2.6
8.1
46
181
A10AB05
ATC
insulin aspart; parenteral
1.9
8.1
100
543
Z97.2
ICD-10 Finland
Presence of dental prosthetic device (complete)(partial)
2.6
8.1
45
176
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
2.5
8.1
49
200
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.6
7.9
220
1493
R03AC13
ATC
formoterol; inhalant
2.2
7.9
65
303
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
2.0
7.9
84
433
F10.20
ICD-10 Finland
Alcohol dependence currently independent
3.2
7.8
30
95
J80
ICD-10 Finland
Adult respiratory distress syndrome
8.5
7.8
16
19
Z94.0
ICD-10 Finland
Kidney transplant status
4.1
7.8
21
52
N02AA05
ATC
oxycodone; systemic
1.6
7.8
208
1400
I33.0
ICD-10 Finland
Acute and subacute infective endocarditis
6.4
7.7
19
30
X59
ICD-10 Finland
Exposure to unspecified factor
1.5
7.7
228
1570
137
Kela drug reimbursment
Uraemia requiring dialysis
4.4
7.7
19
44
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.5
7.7
281
2025
207
Kela drug reimbursment
Chronic arrhythmias
1.6
7.7
185
1215
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
1.9
7.6
100
553
R03AK03
ATC
[U] fenoterol and ipratropium bromide
2.1
7.6
70
342
J01CF05
ATC
flucloxacillin; systemic
2.0
7.6
81
418
H02AB02
ATC
dexamethasone; systemic
1.8
7.6
125
742
J69.0
ICD-10 Finland
Pneumonitis due to food and vomit
3.1
7.6
30
97
D07AA02
ATC
hydrocortisone; topical
1.6
7.6
176
1145
R60.9
ICD-10 Finland
Oedema, unspecified
2.2
7.5
63
296
J10.1
ICD-10 Finland
Influenza with other respiratory manifestations, seasonal influenza virus identified
3.3
7.5
27
82
J44
ICD-10 Finland
Other chronic obstructive pulmonary disease
3.0
7.5
32
108
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
2.3
7.5
58
264
S76
ICPC
Skin infection other
2.1
7.5
67
324
NH1AD
NOMESCO Finland
Ankle and foot CT
3.2
7.4
29
93
UDC00
NOMESCO Finland
Ear microscopy
1.9
7.3
93
509
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
2.7
7.3
37
138
R10.0
ICD-10 Finland
Acute abdomen
2.6
7.2
39
150
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.4
7.2
330
2479
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
4.3
7.2
18
42
E66.2
ICD-10 Finland
Extreme obesity with alveolar hypoventilation
4.3
7.2
18
42
C01AA05
ATC
digoxin; systemic
1.8
7.2
103
586
N18.8
ICD-10 Finland
Other chronic renal failure
2.8
7.2
34
122
JN3AD
NOMESCO Finland
Abdominal CT examination
1.7
7.2
127
769
103
Kela drug reimbursment
Diabetes, insulin-treated
1.5
7.2
313
2331
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
1.9
7.1
95
529
M32.9
ICD-10 Finland
Systemic lupus erythematosus, unspecified
6.6
7.1
17
26
A10AE04
ATC
insulin glargine; parenteral
1.7
7.1
119
710
J90
ICD-10 Finland
Pleural effusion, not elsewhere classified
2.4
7.1
47
200
TGC00
NOMESCO Finland
Bronchial lavation
2.7
7.1
38
146
P15
ICPC
Chronic alcohol abuse
2.5
7.1
42
170
I50
ICD-10 Finland
Heart failure
2.5
7.0
44
183
I48.1
ICD-10 Finland
Persistent atrial fibrillation
2.3
6.9
49
215
TNX33
NOMESCO Finland
Custom moulded cast, unspecified region
2.2
6.9
59
280
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.4
6.9
362
2785
E0000UV, ,
ATC
1.4
6.9
475
3826
GD1BA
NOMESCO Finland
Extensive X-ray examination of thorax
4.0
6.9
19
48
AA1AA
NOMESCO Finland
Head X-ray examination
4.0
6.9
19
48
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.8
6.8
109
641
329
Kela drug reimbursment
Lenalidomide
8.3
6.8
14
17
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.4
6.8
339
2583
F10.30
ICD-10 Finland
Withdrawal symptoms caused by alcohol uncomplicated
4.1
6.8
18
44
S81.8
ICD-10 Finland
Open wound of other parts of lower leg
2.4
6.8
45
192
GCA98
NOMESCO Finland
Other bronchoscopic procedure on bronchus
5.7
6.8
18
32
QDG20
NOMESCO Finland
Operation for chronic ulcer or fistula of skin of lower limb
4.3
6.8
17
40
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
2.1
6.8
62
303
J85.1
ICD-10 Finland
Abscess of lung with pneumonia
16.8
6.7
10
6
ZXD10
NOMESCO Finland
Scheduled procedure
1.4
6.7
423
3355
F17.29
ICD-10 Finland
Addiction caused by tobacco UNS
3.2
6.7
25
78
J02AC01
ATC
fluconazole; systemic
1.4
6.7
371
2879
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.4
6.7
489
3974
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.4
6.7
364
2819
C91.1
ICD-10 Finland
Chronic lymphocytic leukaemia of B-cell type
3.7
6.6
20
54
78020
ICD-8 Finland
Certain symptoms referable to nervous system and special senses, Convulsions
6.5
6.6
16
25
Y57
ICD-10 Finland
Adverse effects in the therapeutic use of other and unspecified drugs and medicaments
3.1
6.6
27
89
Z94.8
ICD-10 Finland
Other transplanted organ and tissue status
7.8
6.6
14
18
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
2.3
6.6
50
226
QCB10
NOMESCO Finland
Major dressing of wound of skin of upper limb
2.8
6.6
31
111
F70.0
ICD-10 Finland
Mild mental retardation, With the statement of no, or minimal, impairment of behaviour
12.3
6.6
11
9
K65.0
ICD-10 Finland
Acute peritonitis
4.2
6.6
17
41
ZXE20
NOMESCO Finland
More than three and less than five hours
1.6
6.6
160
1053
E27.3
ICD-10 Finland
Drug-induced adrenocortical insufficiency
8.7
6.6
13
15
7803A
ICD-9 Finland
General symptoms, Convulsions
3.8
6.5
19
50
F10.39
ICD-10 Finland
Withdrawal symptoms caused by alcohol UNS
3.8
6.5
19
50
48509
ICD-8 Finland
Bronchopneumonia, unspecified
3.8
6.5
19
50
NE1AA
NOMESCO Finland
Pelvis X-ray examination
1.8
6.5
90
507
R59.1
ICD-10 Finland
Generalized enlarged lymph nodes
3.7
6.5
20
55
SPF00
NOMESCO Finland
Reparation of dental prosthesis without impressions
2.6
6.5
37
147
SPAT1149
SPAT
Suture or treatment of traumatic wound
1.6
6.5
147
951
R03AL08
ATC
vilanterol, umeclidinium bromide and fluticasone furoate; inhalant
3.2
6.5
25
80
Z01.8
ICD-10 Finland
Other specified special examinations
1.5
6.5
247
1791
M46.4
ICD-10 Finland
Discitis, unspecified
7.4
6.4
14
19
UDH02
NOMESCO Finland
Rhinopharyngoscopy
1.9
6.4
78
422
J86.00
ICD-10 Finland
Empyema with broncho-pleural fistula
14.4
6.4
10
7
N05AB01
ATC
dixyrazine; systemic
3.8
6.4
19
51
R18
ICD-10 Finland
Ascites
3.1
6.4
26
86
D09AB01
ATC
zinc bandage without supplements; topical
3.1
6.3
25
81
N05CD07
ATC
temazepam; oral
1.6
6.3
135
860
J15.8
ICD-10 Finland
Other bacterial pneumonia
6.0
6.3
16
27
J12.1
ICD-10 Finland
Respiratory syncytial virus pneumonia
5.5
6.3
17
31
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.4
6.3
396
3134
L01AA03
ATC
melphalan; systemic
11.1
6.3
11
10
WX110
NOMESCO Finland
Infiltration anesthesia
1.4
6.3
829
7342
GBB03
NOMESCO Finland
Percutaneous tracheostomy
+∞
6.3
6
*
7100A
ICD-9 Finland
Diffuse diseases of connective tissue, Systemic lupus erythematosus
26.8
6.2
8
*
L01BB01, ,
ATC
26.8
6.2
8
*
ZXE40
NOMESCO Finland
More than seven and less than nine hours
2.7
6.2
32
121
T79.3
ICD-10 Finland
Post-traumatic wound infection, not elsewhere classified
3.2
6.2
24
77
H72.0
ICD-10 Finland
Central perforation of tympanic membrane
2.9
6.2
27
93
A07AA09
ATC
vancomycin; oral
3.4
6.2
21
62
Z72.1
ICD-10 Finland
Alcohol use
3.3
6.2
22
67
R4120
NOMESCO Finland
Occupational therapy
1.9
6.1
75
407
R41.0
ICD-10 Finland
Disorientation, unspecified
2.4
6.1
41
176
JL5BG
NOMESCO Finland
MRI examinaiton of bile and pancreas ducts with high intesity magnet
2.7
6.1
32
122
R03AC03
ATC
terbutaline; inhalant
1.6
6.1
145
949
J01MA02
ATC
ciprofloxacin; systemic
1.4
6.0
432
3485
WX890
NOMESCO Finland
Intesive care monitoring
5.2
6.0
17
33
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
2.0
6.0
66
345

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
703
2923
4.04
136.18
6.7
4.3
—
—
—
0
0
268
811
3.90
76.92
5.1
2.7
12.01
10.60
g/l
2.39
246
744
79
86
9.71
66.29
1.3
1.2
—
—
—
0
0
298
1170
3.00
54.94
10.5
8.6
5.09
5.13
kpa
0.21
276
1114
298
1170
3.00
54.94
10.5
8.6
10.16
12.29
kpa
14.11
276
1115
293
1165
2.95
52.59
10.5
8.7
1.53
1.15
mmol/l
0.65
234
920
200
653
3.44
49.98
2.9
1.8
1.43
1.42
g/l
0.01
183
602
771
4947
2.36
49.19
11.1
6.4
—
—
—
0
0
769
4980
2.32
47.28
10.9
6.4
8.22
8.67
%
3.22
731
4675
765
4955
2.31
46.84
10.5
6.1
2.53
2.88
%
3.72
727
4647
748
4802
2.30
46.75
10.4
6.1
0.59
0.65
%
2.71
704
4498
326
1450
2.66
46.68
10.7
6.8
1.10
1.06
mmol/l
1.52
304
1343
782
5129
2.30
46.23
10.5
6.2
25.49
27.94
%
5.44
745
4832
334
1524
2.60
45.24
2.7
2.1
—
—
—
0
0
770
5051
2.28
45.03
10.1
6.0
59.43
57.01
%
4.67
729
4757
258
1050
2.82
43.69
10.8
9.1
92.89
95.64
%
4.89
245
1012
799
5415
2.22
41.85
10.5
6.3
0.20
0.19
e9/l
0.15
708
4765
65
100
6.79
40.70
2.5
2.8
1.34
1.25
e9/l
0.20
53
85
790
5408
2.16
39.28
10.1
6.0
2.18
1.93
e9/l
0.79
709
4795
771
5237
2.15
39.00
10.1
5.9
0.64
0.59
e9/l
6.19
677
4535
771
5246
2.14
38.71
10.2
5.9
0.04
0.04
e9/l
0.42
676
4546
852
6030
2.18
38.55
15.5
9.0
4.62
4.11
e9/l
6.18
749
5265
235
982
2.70
37.40
13.1
8.5
11.26
9.66
mmol/l
2.42
225
936
334
1653
2.37
37.06
5.6
4.0
0.80
0.81
mmol/l
1.08
311
1550
770
5298
2.10
36.75
9.4
6.4
10.81
11.90
umol/l
1.43
742
5015
90
206
4.62
36.71
2.0
1.8
—
—
—
0
0
137
440
3.36
34.70
2.3
2.0
3.38
1.97
ug/l
0.81
124
390
224
949
2.64
34.50
12.0
9.5
116.68
121.81
g/l
3.03
214
923
380
2047
2.21
34.06
1.9
1.9
—
—
—
0
0
206
847
2.70
33.63
5.8
2.7
67.36
66.19
g/l
0.81
181
766
688
4646
2.01
33.31
13.2
6.7
1.20
1.21
mmol/l
2.84
642
4247
239
1062
2.53
33.28
7.3
5.1
1.63
1.87
mmol/l
0.37
205
856
240
1073
2.51
32.97
7.4
5.0
5.90
5.84
kpa
0.32
233
1039
152
538
3.07
32.70
11.9
11.1
24.39
24.39
mmol/l
0.00
144
523
291
1436
2.32
31.99
3.5
2.7
19.20
23.26
%
5.90
249
1238
217
940
2.57
31.78
10.3
8.3
1.61
1.41
mmol/l
0.65
209
914
725
5086
1.95
30.37
14.7
7.3
1.20
1.21
mmol/l
3.49
626
4348
259
1242
2.35
30.28
4.5
2.9
1.91
1.75
%
1.41
228
1112
298
1528
2.23
29.66
3.5
2.6
2.20
2.31
g/l
2.79
280
1413
54
95
5.89
29.60
1.4
1.3
2.27
2.82
g/l
1.02
36
66
54
95
5.89
29.60
1.4
1.3
0.42
0.41
g/l
0.04
36
66
54
95
5.89
29.60
1.4
1.3
10.15
6.65
g/l
1.57
33
66
138
491
3.02
29.34
2.0
2.0
1.65
1.47
g/l
1.09
117
427
169
673
2.74
29.18
6.0
2.4
—
—
—
0
0
643
4374
1.92
29.10
8.6
5.3
32.89
35.45
g/l
17.78
601
4074
85
223
4.01
28.98
6.5
3.4
—
—
—
0
0
54
97
5.76
28.97
1.4
1.3
—
—
—
0
0
170
682
2.72
28.93
7.0
5.6
—
—
—
0
0
146
545
2.89
28.46
13.5
12.5
—
—
—
0
0
261
1289
2.28
28.32
2.6
1.7
—
—
—
0
0
211
950
2.46
28.27
13.0
9.6
—
—
—
0
0
685
4788
1.90
28.23
19.1
15.7
1.32
1.28
inr
0.46
218
1415
47
80
6.06
26.64
2.6
2.9
665.35
593.83
e6/l
0.19
34
63
46
77
6.16
26.51
2.6
3.0
0.22
0.19
e9/l
0.15
34
63
306
1654
2.11
26.29
3.5
2.6
10.45
13.26
umol/l
10.96
288
1535
202
924
2.40
26.01
4.4
2.8
72.17
69.17
e9/l
0.48
155
713
100
316
3.34
25.88
7.2
3.3
146.21
32.89
mg/l
1.05
79
259
66
157
4.37
25.61
3.8
3.7
1.93
1.23
%
0.44
61
142
99
314
3.33
25.46
7.3
3.3
77.51
75.29
mg/l
0.03
78
254
97
307
3.33
25.03
7.2
3.2
6.09
1.76
ratio
—
5
27
812
6134
1.85
24.83
9.5
5.2
6.87
6.70
mmol/l
1.21
771
5721
48
92
5.38
24.03
2.3
2.6
36.19
36.12
%
0.01
48
92
65
161
4.20
23.93
3.5
3.0
—
—
—
0
0
64
159
4.18
23.47
1.8
1.8
0.52
0.85
g/l
1.44
48
123
58
135
4.45
23.13
1.3
1.4
34.75
31.68
g/l
0.86
47
120
54
121
4.61
22.58
1.3
1.3
1527.89
1673.38
e6/l
0.11
35
86
47
94
5.15
22.45
1.4
1.4
—
—
—
0
0
427
2715
1.85
22.33
2.7
2.2
3.24
2.98
mg/l
1.04
368
2310
183
858
2.32
22.10
5.2
4.3
0.82
0.95
%
0.40
115
312
150
644
2.50
22.03
10.4
8.0
24.65
24.56
mmol/l
0.09
137
608
452
2954
1.81
21.43
4.0
3.3
0.72
0.46
e6/l
1.02
350
2266
486
3249
1.79
21.33
4.3
3.4
42.63
90.45
e6/l
1.30
376
2531
201
997
2.20
21.16
3.2
2.6
0.20
0.21
g/l
1.93
180
928
103
373
2.91
21.11
5.9
2.5
4.37
3.54
g/l
1.22
89
335
465
3096
1.78
20.51
3.6
3.1
—
—
—
0
0
167
777
2.32
20.47
5.0
4.2
0.97
0.62
%
0.61
101
270
494
3354
1.76
20.32
4.5
3.4
50.27
33.45
u/l
0.67
461
3187
641
4683
1.72
20.26
15.2
9.7
0.00
0.00
e9/l
0.41
530
3826
325
1945
1.89
20.26
5.1
3.8
302.63
407.11
ng/l
0.46
270
1508
434
2862
1.77
19.60
4.0
3.2
—
—
—
0
0
169
806
2.26
19.51
10.0
4.6
7.41
7.40
ph
0.38
29
99
404
2616
1.79
19.38
10.7
6.8
—
—
—
0
0
170
817
2.24
19.25
9.9
4.5
5.08
5.16
kpa
0.57
160
783
951
7816
1.79
19.14
12.5
7.4
89.87
80.17
u/l
4.47
911
7354
443
2959
1.75
19.02
7.2
4.1
7.40
7.40
ph
0.25
91
568
168
811
2.23
18.81
5.3
4.4
0.11
0.12
%
0.04
98
264
185
930
2.15
18.71
6.4
4.4
4.76
4.66
kpa
0.21
177
899
108
428
2.66
18.65
7.5
6.3
0.81
0.90
%
1.72
98
401
402
2628
1.76
18.51
7.2
4.3
84.59
88.06
%
2.04
388
2571
857
6875
1.72
18.38
6.1
4.4
209.82
2145.14
e6/l
1.64
11
119
534
3782
1.70
18.38
4.8
3.9
32.71
119.33
e6/l
3.28
390
2702
94
350
2.82
18.29
5.6
2.6
12.80
10.30
g/l
1.42
79
311
108
434
2.62
18.13
7.4
6.2
1.83
1.58
%
1.66
97
407
55
150
3.78
17.77
7.7
6.8
11.44
11.53
mg/l
0.05
50
135
45
108
4.28
17.28
1.3
1.3
128048.28
140021.29
e6/l
0.05
25
66
70
228
3.19
17.23
9.0
9.3
103.84
105.20
mmol/l
1.02
61
205
70
228
3.19
17.23
9.0
9.3
12.00
11.39
mmol/l
0.70
61
205
279
1666
1.86
17.19
1.8
1.6
—
—
—
0
0
342
2177
1.77
17.04
3.6
3.0
510.51
560.92
mosm/kgh2o
4.36
303
1881
85
315
2.82
16.69
3.2
1.4
0.23
0.24
g/l
0.34
78
298
272
1634
1.84
16.36
2.8
2.4
30.43
29.80
s
0.88
266
1585
453
3147
1.67
16.29
3.2
2.6
55.81
59.63
u/l
0.51
426
2909
48
127
3.89
16.19
4.2
4.1
—
—
—
0
0
431
2965
1.68
16.04
3.9
3.1
2576.97
1571.67
ng/l
2.94
369
2541
167
855
2.09
16.01
4.5
3.0
313.39
218.90
ng/l
1.49
153
785
155
776
2.13
15.75
5.4
4.4
0.00
0.48
%
0.66
84
227
71
247
2.98
15.63
6.4
3.7
—
—
—
0
0
305
1926
1.76
15.43
2.0
1.7
1200.37
1176.32
nmol/l
0.14
234
1469
26
43
6.15
15.16
2.7
3.7
230.91
340.00
e6/l
0.35
11
19
83
322
2.68
14.94
9.2
7.9
1.33
1.33
mmol/l
0.02
72
279
327
2125
1.72
14.87
2.2
1.5
2.51
2.40
g/l
0.35
227
1283
39
95
4.20
14.71
4.0
2.0
—
—
—
0
0
213
1224
1.88
14.62
1.7
1.5
—
—
—
0
0
80
308
2.70
14.62
4.8
2.5
37.04
37.82
g/l
0.53
66
270
33
71
4.74
14.52
2.7
3.0
43.00
39.59
%
0.37
16
34
131
634
2.18
14.48
7.5
4.2
119.74
127.64
g/l
3.54
126
620
277
1733
1.76
14.36
3.4
3.1
3.47
1.84
e6/l
1.23
147
974
41
106
3.96
14.30
1.2
1.4
—
—
—
0
0
40
102
4.01
14.21
1.3
1.3
5.81
6.30
mmol/l
0.49
34
97
285
1808
1.74
14.04
3.4
2.9
2.09
0.99
e6/l
1.89
159
1050
76
293
2.69
13.85
1.3
1.1
—
—
—
0
0
213
1246
1.85
13.77
1.9
1.6
—
—
—
0
0
208
1212
1.85
13.61
4.7
3.2
8.18
8.70
umol/l
0.14
171
1050
71
268
2.74
13.48
3.0
3.4
35.86
35.21
umol/l
0.09
64
241
591
4532
1.55
13.38
4.0
2.9
190.88
130.68
ug/l
2.78
545
4173
336
2265
1.65
13.08
3.7
2.6
8.42
5.33
e6/l
2.03
306
2044
66
244
2.80
13.04
7.0
4.5
2.62
2.68
mmol/l
0.05
44
161
60
214
2.89
12.67
7.9
3.0
—
—
—
0
0
25
28
9.08
12.26
2.0
2.0
—
—
—
0
0
120
604
2.09
11.97
11.5
4.8
—
—
—
0
0
45
142
3.25
11.72
3.7
2.8
—
—
—
0
0
27
60
4.57
11.45
1.4
1.2
—
—
—
0
0
146
801
1.93
11.43
1.4
1.5
—
—
—
0
0
1144
10391
1.81
11.28
32.1
14.4
40.26
24.86
mg/l
23.08
1026
8209
70
290
2.49
11.06
6.9
4.2
7.41
7.41
ph
0.11
65
260
53
192
2.83
10.91
4.4
3.7
57.51
57.12
%
0.06
53
192
123
649
1.99
10.78
1.6
1.3
151.67
258.77
u/ml
1.27
110
592
61
240
2.62
10.72
3.7
2.4
123.65
130.25
g/l
1.29
48
185
455
3418
1.51
10.67
4.9
3.4
2.33
2.35
mmol/l
1.64
402
3005
209
1317
1.70
10.30
1.6
1.3
602.11
479.56
titre
0.39
57
271
337
2403
1.54
9.97
1.8
1.6
19.73
19.89
nmol/l
0.07
295
2035
26
64
4.12
9.72
2.3
1.5
—
—
—
0
0
842
7216
1.47
9.71
5.9
4.2
—
—
—
0
0
36
112
3.28
9.63
1.3
1.6
—
—
—
0
0
35
107
3.33
9.62
3.0
2.7
1.93
1.92
g/24h
0.01
18
57
57
230
2.55
9.55
4.4
2.6
15.38
16.14
%
0.86
37
126
524
4130
1.45
9.32
2.4
2.0
93.21
93.93
pmol/l
0.14
313
2181
48
180
2.73
9.30
1.9
1.7
—
—
—
0
0
45
166
2.77
9.00
1.7
1.8
—
—
—
0
0
55
228
2.47
8.73
1.9
1.6
113.60
107.92
u/ml
—
10
40
137
802
1.79
8.72
6.6
4.5
108.08
86.71
ng/l
1.19
118
709
493
3882
1.43
8.64
5.3
3.7
45.92
58.19
ng/l
0.46
368
2714
867
7555
1.44
8.54
6.0
4.0
21.23
11.96
mm/h
24.80
808
6945
594
4846
1.41
8.49
4.0
2.7
—
—
—
0
0
12
6
20.17
8.47
1.5
1.0
—
—
—
0
0
21
49
4.34
8.42
2.3
1.9
—
—
—
0
0
19
41
4.69
8.36
1.6
1.3
—
—
—
0
0
357
2665
1.47
8.23
4.7
2.9
375.07
6929.55
umol/l
9.87
322
2329
43
163
2.69
8.19
1.6
1.5
—
—
—
0
0
422
3265
1.43
8.01
4.2
3.3
6.52
7.87
mmol/l
7.97
351
2766
56
245
2.34
7.92
1.8
1.5
—
—
—
0
0
157
981
1.68
7.92
2.0
1.4
—
—
—
0
0
309
2261
1.48
7.84
2.2
1.9
2.10
1.25
mg/l
1.95
250
1721
53
228
2.38
7.79
5.9
5.2
—
—
—
0
0
155
971
1.68
7.74
2.9
2.1
336.17
371.68
nmol/l
1.07
140
892
423
3292
1.42
7.71
3.9
2.5
—
—
—
0
0
46
188
2.50
7.56
4.3
3.3
4.80
4.21
e9/l
0.70
46
188
55
245
2.30
7.48
1.7
1.8
40992.58
15587.85
e6/l
1.15
43
181
380
2921
1.42
7.36
4.3
3.3
1310.99
298.08
mg/l
1.76
263
1957
505
4084
1.39
7.26
2.9
2.3
74.69
75.54
nmol/l
0.27
456
3645
151
958
1.65
7.18
3.2
2.3
37.93
83.26
u/l
0.43
122
810
118
702
1.75
7.11
3.4
2.7
7.40
6.11
e9/l
0.23
95
575
774
6717
1.37
7.10
4.8
3.2
75.07
48.00
u/l
5.17
724
6266
45
188
2.44
7.07
1.4
1.6
56.13
69.48
mmol/l
1.38
32
161
77
402
1.97
7.00
3.0
3.1
21.68
21.67
s
0.01
69
361
39
155
2.56
6.81
3.2
1.8
—
—
—
0
0
63
309
2.09
6.80
4.7
3.3
—
—
—
0
0
21
58
3.66
6.76
2.8
3.7
7.37
7.43
ph
—
7
18
26
84
3.14
6.61
1.8
1.6
1.44
1.22
promille
0.28
21
69
387
3033
1.39
6.58
2.6
2.2
327.48
261.61
u/l
0.31
355
2856
391
3074
1.39
6.52
4.6
3.9
28.73
9.53
mg/mmol
2.22
267
2009
113
686
1.71
6.35
1.5
1.4
—
—
—
0
0
990
9031
1.40
6.13
35.0
17.2
14.96
14.81
%
0.47
970
8882
32
122
2.66
6.09
1.9
1.6
65.00
61.26
%
0.20
23
82
95
557
1.76
6.04
1.4
1.2
—
—
—
0
0
51
245
2.13
5.84
1.5
1.2
2.84
2.50
u/ml
—
10
24
53
259
2.09
5.81
1.4
1.2
28.08
16.31
u/ml
—
10
10
51
247
2.11
5.73
1.5
1.2
9.31
14.35
u/ml
0.27
17
36
63
331
1.95
5.67
10.7
8.1
1.54
1.50
mg/l
0.11
57
307
19
56
3.43
5.59
1.9
3.3
—
—
—
0
0
46
219
2.14
5.41
1.1
1.2
—
—
—
0
0
37
163
2.31
5.24
1.1
1.1
—
—
—
0
0
278
2139
1.38
5.13
2.0
1.7
48246067.61
14678296.80
pmol/l
0.31
228
1785
320
2520
1.36
5.10
3.8
2.4
—
—
—
0
0
124
818
1.57
5.04
6.1
3.9
1.22
1.22
mmol/l
0.07
110
705
51
262
1.98
4.93
2.9
2.1
10.58
11.77
mg/l
0.45
46
238
32
136
2.39
4.93
3.3
7.3
6.65
6.82
mmol/l
0.16
32
112
13
24
5.46
4.92
1.1
1.2
—
—
—
0
0
13
24
5.46
4.92
1.5
1.5
—
—
—
0
0
37
168
2.24
4.91
1.6
1.4
—
—
—
0
0
70
402
1.78
4.82
2.4
2.4
9813.98
4098.18
u/l
0.53
28
169
29
121
2.43
4.66
1.3
1.1
—
—
—
0
0
56
306
1.87
4.54
6.9
4.4
3.96
3.92
mmol/l
0.20
56
301
12
23
5.26
4.46
1.6
1.7
—
—
—
0
0
584
5079
1.27
4.34
5.1
3.6
0.01
0.00
estimate
0.40
144
1041
26
107
2.46
4.32
1.2
1.3
—
—
—
0
0
15
38
3.98
4.30
5.2
3.9
—
—
—
0
0
18
61
2.98
4.29
1.6
3.0
—
—
—
0
0
69
410
1.72
4.26
8.7
4.7
—
—
—
0
0
15
46
3.29
4.19
1.6
1.3
1.00
1.50
%
—
5
6
580
5057
1.26
4.17
6.7
5.0
0.00
0.00
estimate
0.50
135
993
131
913
1.48
4.16
5.4
3.7
—
—
—
0
0
586
5117
1.26
4.15
5.0
3.6
0.00
0.01
estimate
0.80
128
953
128
889
1.49
4.13
2.9
2.5
5.79
7.09
ug/l
0.68
104
784
35
169
2.10
4.04
1.3
1.1
—
—
—
0
0
17
58
2.96
4.02
1.1
1.0
—
—
—
0
0
152
1100
1.43
3.98
1.7
1.7
—
—
—
0
0
70
427
1.68
3.95
4.2
4.0
0.43
0.29
g/l
0.65
37
198
60
351
1.74
3.93
1.6
1.2
0.45
1.50
u/ml
—
6
20
1113
10552
1.37
3.93
35.3
16.8
138.79
139.58
mmol/l
18.20
1089
10259
29
132
2.22
3.88
4.4
2.5
—
—
—
0
0
25
107
2.36
3.84
1.6
1.9
—
—
—
0
0
1114
10575
1.36
3.80
35.5
16.9
3.97
3.98
mmol/l
0.58
1086
10265
24
102
2.38
3.75
1.0
1.1
—
—
—
0
0
17
61
2.81
3.69
1.1
1.0
—
—
—
0
0
57
336
1.73
3.66
4.1
2.7
—
—
—
0
0
22
91
2.44
3.65
2.0
1.4
26.29
28.03
%
0.08
17
60
20
79
2.56
3.64
3.8
9.2
9.86
10.89
%
0.47
20
79
16
56
2.88
3.63
1.3
1.4
—
—
—
0
0
473
4082
1.25
3.57
4.8
3.4
5.75
5.86
ph
0.24
18
302
46
258
1.81
3.50
1.5
1.4
296.72
245.36
u/ml
0.29
25
138
56
894
0.61
3.31
1.2
1.3
—
—
—
0
0
20
83
2.43
3.31
1.1
1.2
—
—
—
0
0
17
65
2.64
3.31
19.7
19.4
1443.71
1428.89
nmol/l
0.03
17
65
11
28
3.95
3.29
1.3
1.0
—
—
—
0
0
25
116
2.18
3.23
1.4
1.2
—
—
—
0
0
26
124
2.12
3.15
2.2
2.4
—
—
—
0
0
18
73
2.49
3.13
2.5
2.0
—
—
—
0
0
67
431
1.58
3.12
1.4
1.3
—
—
—
0
0
25
118
2.14
3.11
1.1
1.2
—
—
—
0
0
25
119
2.12
3.05
1.0
1.1
—
—
—
0
0
49
295
1.69
2.97
1.4
1.5
298.08
291.41
ug/g
0.07
25
175
35
191
1.86
2.94
1.5
1.2
58.67
28.99
u/ml
—
7
12
13
46
2.84
2.92
3.3
1.8
—
—
—
0
0
19
82
2.34
2.92
1.1
1.1
222.65
44.23
mg/l
0.74
14
66
293
3471
0.80
2.88
2.9
2.8
—
—
—
0
0
15
58
2.60
2.88
56.0
31.2
112.27
142.57
ug/l
0.78
15
51
12
39
3.10
2.77
1.7
2.4
1187.50
959.29
e6/l
—
6
34
38
218
1.77
2.74
2.4
3.1
0.77
0.87
nmol/l
0.69
29
170
60
389
1.57
2.74
3.1
2.0
—
—
—
0
0
12
40
3.02
2.69
2.8
2.6
—
—
—
0
0
60
391
1.56
2.68
3.1
3.5
104.30
3791.85
u/ml
0.81
46
330
8
19
4.23
2.68
1.3
1.3
—
—
—
0
0
16
68
2.37
2.56
1.6
1.5
—
—
—
0
0
63
420
1.53
2.56
1.3
1.2
—
—
—
0
0
12
42
2.87
2.55
1.0
1.0
—
—
—
0
0
18
81
2.24
2.54
1.7
2.4
633.78
641.78
ml
—
9
54
15
62
2.44
2.54
1.7
2.4
496.00
499.36
min
—
8
45
37
216
1.73
2.54
1.5
1.9
—
—
—
0
0
229
1885
1.26
2.53
3.8
3.0
2.48
2.45
mmol/l
1.91
191
1647
17
75
2.28
2.51
1.9
1.4
7.19
1.46
u/ml
—
9
46
325
2795
1.22
2.39
5.1
3.3
—
—
—
0
0
22
111
2.00
2.36
4.0
3.4
—
—
—
0
0
48
308
1.58
2.33
1.2
1.2
—
—
—
0
0
9
28
3.23
2.31
1.8
2.1
—
—
—
0
0
6
13
4.63
2.27
1.0
1.8
—
—
—
0
0
8
23
3.49
2.27
2.4
3.2
14.40
15.97
ml/dl
—
8
18
11
41
2.70
2.21
1.2
1.1
—
—
—
0
0
167
1347
1.27
2.20
1.4
1.2
—
—
—
0
0
1120
10807
1.25
2.18
27.8
13.6
—
—
—
0
0
7
19
3.70
2.15
9.1
7.9
—
—
—
0
0
8
25
3.21
2.09
9.3
7.2
—
—
—
0
0
16
75
2.15
2.09
4.3
3.5
—
—
—
0
0
9
31
2.92
2.07
1.4
1.9
—
—
—
0
0
21
110
1.92
2.06
1.5
2.4
—
—
—
0
0
37
576
0.63
2.05
1.2
1.4
—
—
—
0
0
17
83
2.06
2.01
1.7
1.5
—
—
—
0
0
8
26
3.09
2.01
1.8
1.7
—
—
—
0
0
129
1023
1.29
1.96
3.6
4.2
15.77
25.37
ug/l
0.38
107
855
8
27
2.97
1.93
2.4
1.9
—
—
—
0
0
8
27
2.97
1.93
9.5
9.0
41.02
92.51
g/mol
—
8
22
38
243
1.58
1.91
1.5
1.9
383.37
41.91
e6/l
1.02
30
192
38
243
1.58
1.91
1.6
1.8
3.52
3.80
mmol/l
0.54
33
226
38
243
1.58
1.91
1.6
1.9
1668.10
620.93
e6/l
0.40
30
197
13
58
2.25
1.91
1.7
1.2
153.77
137.30
nmol/l
0.32
13
58
941
9815
0.85
1.81
4.5
4.2
1.38
1.43
mmol/l
2.42
873
9030
64
462
1.41
1.81
3.0
2.0
—
—
—
0
0
22
123
1.80
1.80
1.6
1.4
—
—
—
0
0
108
847
1.30
1.80
1.5
1.4
—
—
—
0
0
67
493
1.38
1.71
2.9
2.0
—
—
—
0
0
11
48
2.30
1.70
1.1
1.1
384.93
184.06
iu/ml
0.36
11
48
14
68
2.07
1.70
3.2
2.8
—
—
—
0
0
18
319
0.56
1.70
18.6
9.7
—
—
—
0
0
67
495
1.37
1.68
2.9
2.0
—
—
—
0
0
329
2920
1.17
1.67
4.9
3.9
—
—
—
0
0
8
31
2.59
1.66
1.0
1.1
—
—
—
0
0
7
25
2.81
1.65
1.1
1.5
—
—
—
0
0
16
83
1.94
1.65
3.4
2.4
1.75
2.12
u/field
—
8
34
67
498
1.36
1.62
2.9
2.0
—
—
—
0
0
5
14
3.58
1.61
1.2
6.8
—
—
—
0
0
35
230
1.54
1.61
4.2
2.4
—
—
—
0
0
67
499
1.36
1.61
4.8
3.8
—
—
—
0
0
6
20
3.01
1.58
1.2
1.0
—
—
—
0
0
6
20
3.01
1.58
1.2
1.0
—
—
—
0
0
6
20
3.01
1.58
1.2
1.0
—
—
—
0
0
152
1265
1.23
1.56
1.3
1.3
—
—
—
0
0
268
2359
1.17
1.50
4.3
3.5
—
—
—
0
0
425
3871
1.15
1.50
2.1
2.1
—
—
—
0
0
954
9896
0.87
1.50
4.6
4.3
4.46
4.56
mmol/l
1.90
893
9157
14
72
1.95
1.49
1.1
1.0
—
—
—
0
0
22
132
1.68
1.46
2.0
1.6
—
—
—
0
0
24
148
1.63
1.45
1.3
1.2
5.85
5.13
u/ml
0.10
13
61
119
978
1.24
1.40
8.4
4.4
—
—
—
0
0
48
348
1.39
1.38
1.6
1.7
—
—
—
0
0
6
23
2.62
1.37
1.2
1.3
—
—
—
0
0
39
273
1.44
1.36
4.7
4.9
—
—
—
0
0
29
426
0.67
1.31
1.4
1.6
—
—
—
0
0
308
2771
1.15
1.29
6.1
3.8
0.01
0.01
estimate
0.08
123
955
5
18
2.78
1.28
1.8
6.7
—
—
—
0
0
5
18
2.78
1.28
3.2
4.0
—
—
—
0
0
12
62
1.94
1.28
1.2
1.1
1.12
1.06
ratio
—
5
23
8
35
2.29
1.27
2.1
2.5
—
—
—
0
0
45
330
1.38
1.24
1.2
1.3
171.32
236.05
miu/ml
0.52
16
157
12
215
0.55
1.23
1.3
1.5
—
—
—
0
0
63
488
1.31
1.22
3.0
1.8
—
—
—
0
0
5
19
2.64
1.21
2.2
3.7
—
—
—
0
0
6
26
2.31
1.18
1.5
1.5
—
—
—
0
0
15
248
0.60
1.16
1.0
1.1
—
—
—
0
0
17
102
1.68
1.16
1.8
1.7
—
—
—
0
0
8
39
2.06
1.15
1.1
1.1
1176.75
1591.59
miu/ml
—
8
39
12
210
0.57
1.15
1.3
1.4
—
—
—
0
0
5
20
2.51
1.15
9.6
5.9
1.72
2.81
mg/l
—
5
15
12
209
0.57
1.13
1.3
1.4
—
—
—
0
0
738
7039
1.11
1.12
4.8
3.8
—
—
—
0
0
11
58
1.90
1.12
2.5
1.8
—
—
—
0
0
23
151
1.53
1.12
4.3
3.2
8.37
9.79
umol/l
0.17
17
114
200
2256
0.87
1.10
2.5
3.1
0.70
0.76
ug/l
0.54
131
1492
330
3015
1.13
1.09
1.5
1.5
—
—
—
0
0
800
7670
1.11
1.09
3.9
3.8
14.69
14.80
pmol/l
0.62
718
6930
69
552
1.26
1.07
3.1
3.3
4.66
4.63
pmol/l
0.07
63
489
963
9332
1.12
1.06
4.7
4.5
1.95
2.05
mu/l
0.35
876
8507
916
9456
0.90
1.06
4.2
3.9
1.36
1.28
mmol/l
2.60
845
8647
15
91
1.66
1.00
3.0
3.5
29.16
29.68
mg/l
—
9
69
9
48
1.88
1.00
1.6
1.2
135.11
526.29
u/l
—
9
42
5
23
2.18
0.98
1.8
2.0
—
—
—
0
0
55
434
1.28
0.97
2.0
1.8
—
—
—
0
0
17
259
0.65
0.96
1.1
1.2
—
—
—
0
0
25
174
1.45
0.95
6.5
3.5
—
—
—
0
0
980
10059
0.90
0.94
5.0
4.7
2.59
2.69
mmol/l
2.95
902
9244
53
423
1.26
0.87
2.7
2.7
—
—
—
0
0
6
30
2.00
0.87
1.5
2.2
—
—
—
0
0
179
1600
1.14
0.86
1.3
1.3
47.55
32.38
iu/ml
0.61
64
501
33
248
1.34
0.84
2.7
2.4
—
—
—
0
0
16
105
1.53
0.82
1.2
1.2
—
—
nmol/l
—
0
0
1112
10914
1.13
0.81
17.2
10.1
27.89
26.60
u/l
1.03
1076
10518
46
365
1.27
0.81
1.9
1.5
274.62
311.56
mu/l
0.58
37
332
950
9739
0.91
0.80
4.9
4.4
6.07
5.94
mmol/l
1.86
858
8825
0
25
0.00
0.79
0.0
1.1
—
—
—
0
0
61
504
1.22
0.76
2.8
2.4
—
—
—
0
0
6
34
1.77
0.76
2.3
2.4
91.27
106.59
ug/l
—
6
34
5
24
2.09
0.74
2.8
2.0
19.72
16.39
umol/l
—
5
24
24
176
1.37
0.73
1.3
1.3
—
—
—
0
0
56
674
0.82
0.72
1.2
1.2
163.47
139.46
iu/ml
0.13
19
258
7
41
1.71
0.70
1.3
1.2
—
—
—
0
0
43
347
1.25
0.68
1.6
1.5
10.82
7.98
u/l
0.85
35
275
5
28
1.79
0.66
1.2
1.3
—
—
—
0
0
894
9158
0.92
0.65
7.0
5.7
41.50
39.87
mmol/mol
4.11
827
8454
23
173
1.34
0.62
1.1
1.1
—
—
—
0
0
17
233
0.73
0.61
1.6
1.8
5.46
5.29
iu/l
—
5
72
18
131
1.38
0.59
1.2
1.1
—
—
—
0
0
27
210
1.29
0.59
1.8
1.3
—
—
—
0
0
19
140
1.36
0.58
1.1
1.2
—
—
—
0
0
11
73
1.51
0.56
1.1
1.1
—
—
—
0
0
8
55
1.46
0.56
1.3
1.3
—
—
—
0
0
32
258
1.25
0.54
2.5
2.4
176.43
91.20
ug/min
0.60
21
157
6
39
1.54
0.53
1.5
1.6
1.45
6.42
nmol/l
—
6
30
6
39
1.54
0.53
1.0
1.0
—
—
—
0
0
9
63
1.43
0.52
2.2
2.1
3.20
3.25
ug/l
—
9
56
9
64
1.41
0.51
2.1
1.5
1.00
0.98
g/l
—
9
64
73
644
1.14
0.48
3.6
2.9
—
—
—
0
0
29
235
1.24
0.48
4.1
3.7
47.34
26.21
mg/l
1.44
23
155
167
1546
1.09
0.48
1.2
1.2
23.77
11.26
u/ml
0.60
43
597
18
137
1.32
0.47
1.2
1.5
0.22
0.31
nmol/l
0.69
12
111
16
210
0.76
0.46
1.4
1.7
—
—
—
0
0
251
2367
1.07
0.46
1.3
1.3
4.50
1.51
u/ml
0.72
48
605
22
174
1.27
0.45
1.1
1.1
—
—
—
0
0
7
50
1.40
0.45
1.4
1.6
—
—
—
0
0
7
50
1.40
0.45
1.3
1.2
—
—
—
0
0
16
121
1.33
0.44
1.8
2.7
—
—
—
0
0
8
56
1.43
0.42
3.9
2.9
1727.50
1998.90
ml
—
8
50
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
1.2
—
1.98
—
0
16
18
227
0.79
0.40
1.4
1.1
6.37
2.59
u/ml
0.39
12
131
1170
11594
1.09
0.40
42.8
21.0
7.86
6.78
e9/l
11.94
1142
11259
900
8853
1.05
0.37
38.4
18.3
330.73
333.18
g/l
10.79
886
8778
15
190
0.79
0.35
1.2
1.3
—
—
—
0
0
16
200
0.80
0.34
1.1
1.1
0.91
1.34
u/ml
—
8
104
1168
11585
1.08
0.34
43.0
21.0
251.89
247.28
e9/l
1.23
1144
11279
6
45
1.33
0.33
4.3
14.6
—
—
—
0
0
92
846
1.09
0.33
5.0
3.3
—
—
—
0
0
1168
11587
1.07
0.33
43.5
21.2
38.32
40.22
%
17.35
1063
10807
6
87
0.69
0.33
2.0
4.9
—
43.39
—
0
27
6
47
1.28
0.32
1.2
1.3
1.39
1.53
g/l
—
6
47
1168
11591
1.07
0.31
42.7
20.9
91.22
90.71
fl
2.74
1150
11415
1168
11593
1.07
0.30
42.7
20.8
30.24
30.26
pg
0.14
1150
11415
1168
11594
1.07
0.30
42.8
20.9
4.29
4.51
e12/l
30.33
1140
11256
14
111
1.26
0.30
1.1
1.2
—
—
—
0
0
8
106
0.75
0.29
1.0
1.1
—
—
—
0
0
33
376
0.87
0.28
1.0
1.1
—
—
—
0
0
1168
11598
1.07
0.28
43.2
21.1
128.55
135.75
g/l
39.63
1149
11414
105
1120
0.93
0.27
1.5
1.5
—
—
—
0
0
9
72
1.25
0.25
1.3
1.1
—
—
—
0
0
56
609
0.92
0.23
1.2
1.2
—
—
—
0
0
5
38
1.32
0.23
4.6
2.9
—
—
—
0
0
5
38
1.32
0.23
9.2
5.7
—
—
—
0
0
33
369
0.89
0.23
1.0
1.1
—
—
—
0
0
5
39
1.28
0.23
1.8
3.2
—
—
—
0
0
86
916
0.93
0.22
2.6
2.1
11.26
12.67
nmol/l
0.90
71
819
5
42
1.19
0.21
3.4
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
2.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
6
49
1.23
0.20
1.3
1.2
—
—
—
0
0
105
1102
0.95
0.18
1.5
1.7
—
—
—
0
0
41
377
1.09
0.18
1.5
1.5
22.39
21.08
iu/l
0.12
33
312
87
827
1.06
0.16
1.1
1.2
—
—
—
0
0
123
1281
0.96
0.16
2.4
2.4
187.82
127.43
ug/g
1.15
93
1016
8
68
1.18
0.16
1.4
1.2
—
—
—
0
0
6
79
0.76
0.15
1.7
1.3
159.92
167.70
pmol/l
—
6
79
7
86
0.81
0.14
1.0
1.2
—
—
—
0
0
38
405
0.94
0.12
3.7
3.0
27.68
51.50
u/ml
1.18
38
387
13
147
0.88
0.11
1.1
1.1
10.54
2.13
u/ml
—
5
62
383
3883
0.98
0.11
4.6
5.0
2.34
2.64
ug/l
0.41
333
3454
21
229
0.92
0.10
2.4
1.7
168.19
219.22
pmol/l
1.74
21
216
5
45
1.11
0.09
1.0
1.1
—
—
—
0
0
14
155
0.90
0.09
1.0
1.0
7.97
4.07
u/ml
—
7
85
6
54
1.11
0.09
1.7
1.4
5.83
6.19
mmol/l
—
6
54
19
205
0.93
0.08
1.1
1.1
5.54
8.04
u/ml
0.31
12
123
19
177
1.07
0.06
1.1
1.1
—
9.74
—
0
9
11
120
0.92
0.05
1.2
1.5
—
—
—
0
0
109
1078
1.01
0.02
1.4
1.3
—
—
—
0
0
16
152
1.05
0.02
1.1
1.2
—
—
—
0
0
229
2297
1.00
0.00
6.5
3.8
1.02
1.02
kg/l
0.09
35
321
266
2653
1.00
0.00
1.7
1.7
1.45
1.37
mmol/l
0.57
232
2239
23
227
1.01
0.00
1.3
1.3
—
—
—
0
0
5
52
0.96
0.00
1.2
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.6
—
34.88
—
0
8
0
5
0.00
-0.00
0.0
5.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
81.50
—
0
6
14
140
1.00
-0.00
1.0
1.1
1.98
6.40
u/ml
—
5
68
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
6
68
0.88
-0.00
3.3
1.5
88.67
81.60
umol/l
—
6
68

Mortality – FinRegistry

Association

Association between endpoint PNEUMO_SEPTHICHE and mortality.

Females

Parameter HR [95% CI] p-value
PNEUMO_SEPTHICHE 2.811 [2.33, 3.39] < 0.001
Birth year 0.992 [0.98, 1.0] 0.068

During the follow-up period (1.1.1998 — 31.12.2019), 996 out of 4840 females with PNEUMO_SEPTHICHE died.

Males

Parameter HR [95% CI] p-value
PNEUMO_SEPTHICHE 3.457 [2.88, 4.14] < 0.001
Birth year 0.984 [0.97, 0.99] 0.001

During the follow-up period (1.1.1998 — 31.12.2019), 1385 out of 5934 males with PNEUMO_SEPTHICHE died.

Mortality risk

Mortality risk for people of age

years, who have PNEUMO_SEPTHICHE.

N-year risk Females Males
1 0.271% 0.64%
5 1.424% 3.663%
10 3.592% 8.811%
15 7.108% 16.967%
20 12.402% 26.779%

Relationships between endpoints

Index endpoint: PNEUMO_SEPTHICHE – Pneumococcal septicemia

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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