Risteys ·

OMOP concept ID	Test name	Measurement unit (harmonized unit)	N people	N records	Missing measurement value	Harmonized value distribution	Test outcome NA N A AA L LL H HH
3040668	b-dm2alld	— (—)	134	135	100.00%	Distribution not available

LabWAS

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

Symptoms and signs involving the nervous and musculoskeletal systems

18.78

95.11

1.0

—

Other symptoms and signs involving the nervous and musculoskeletal systems

24.00

94.03

1.0

—

Diseases of the myoneural junction and muscle

34.45

64.51

1.0

—

Myalgia

31.00

51.80

1.0

—

Other soft tissue disorders, not elsewhere classified

11.39

51.00

1.0

—

Pain in limb

8.51

26.73

1.0

—

Soft tissue disorders

6.70

22.99

1.0

—

Pain in joint

8.56

19.84

1.0

—

Spondylosis

6.55

17.06

1.0

—

General examination and investigation of persons without complaint and reported diagnosis

6.61

17.00

1.0

—

Pain, not elsewhere classified

9.54

16.98

1.0

—

Other and unspecified myopathies

27.67

16.49

1.0

—

Spondylopathies

5.39

16.47

1.0

—

Other specific joint derangements/joint disorders

5.20

16.20

1.0

—

Oral corticosteroids

4.01

15.60

1.0

—

Neurological diseases

6.30

15.45

1.0

—

Codeine

4.63

14.94

1.0

—

Inflammatory bowel disease treatment related agents

3.84

14.71

1.0

—

Fibromyalgia

36.16

14.43

1.0

—

ILD medications: prednisolone, methylprednisolone, prednisone

3.77

13.27

1.0

—

Shoulder lesions

5.73

13.06

1.0

—

Other enthesopathies

10.78

12.85

1.0

—

Asthma (mode)

4.26

12.08

1.0

—

ILD medications

3.58

12.06

1.0

—

Cervical disc disorders

6.26

11.99

1.0

—

Chronic lower respiratory diseases

3.36

11.93

1.0

—

Concussion

7.42

11.82

1.0

—

Asthma

4.16

11.65

1.0

—

Rheumatism, unspecified

30.06

11.63

1.0

—

Asthma, excluding more controls

4.14

11.54

1.0

—

Sleep disorders (combined)

3.52

11.51

1.0

—

Diseases of the musculoskeletal system and connective tissue

7.89

11.43

1.0

—

Pain (limb, back, neck, head abdominally)

5.61

11.25

1.0

—

Dyspnoea

3.59

11.02

1.0

—

General symptoms and signs

3.44

10.82

1.0

—

Other intervertebral disc disorders

4.08

10.78

1.0

—

Depression or dysthymia

4.57

10.76

1.0

—

Sleep apnoea

3.48

10.67

1.0

—

Codeine or tramadol medication

3.25

10.61

1.0

—

Nerve, nerve root and plexus disorders

3.29

10.55

1.0

—

First line medication for Crohn's disease

3.38

10.44

1.0

—

Asthma (only as main-diagnosis)

4.06

10.36

1.0

—

Other dorsopathies, not elsewhere classified

3.78

10.35

1.0

—

Endocrine, nutritional and metabolic diseases

3.98

10.29

1.0

—

Asthma, including avohilmo

3.14

10.23

1.0

—

Dorsalgia

3.78

10.18

1.0

—

Asthma (only as main-diagnosis), excluding more controls

4.01

10.15

1.0

—

Other systemic involvement of connective tissue (FG)

7.10

10.04

1.1

1.0

—

Disorders of synovium and tendon

6.01

9.99

1.0

—

Finngen Rheumatological endpoints

3.39

9.94

1.0

—

Low back pain

4.15

9.86

1.0

—

Opioids

3.71

9.56

1.0

—

Medical observation and evaluation for suspected diseases and conditions

4.77

9.45

1.0

—

Asthma/COPD (KELA code 203)

3.27

9.39

1.0

—

Malaise and fatigue

5.21

9.37

1.0

—

Episodal and paroxysmal disorders

3.25

8.83

1.0

—

Dorsopathies

3.47

8.68

1.0

—

Other antidepressants

3.15

8.67

1.0

—

Migraine

4.58

8.62

1.0

—

Other special examinations and investigations of persons without complaint or reported diagnosis

4.54

8.62

1.0

—

Persons encountering health services in other circumstances, wide

2.88

8.43

1.0

—

Abnormalities of breathing

3.37

8.34

1.0

—

Intracranial trauma

5.52

8.10

1.0

—

Parasetamol

3.55

7.99

1.0

—

Any gastric operation

3.57

7.99

1.0

—

GASTRO-related operations

3.57

7.99

1.0

—

Asthma, hospital admissions , main diagnosis only

3.08

7.98

1.0

—

Sleep apnoea, including avohilmo

2.97

7.93

1.0

—

Asthma, unspecified (mode)

4.15

7.87

1.0

—

Asthma, unspecified (mode), excluding more controls

4.11

7.76

1.0

—

Metabolic disorders

2.95

7.74

1.0

—

Other systemic involvement of connective tissue

5.36

7.72

1.1

1.0

—

Rotator cuff syndrome

4.95

7.68

1.0

—

Obesity related asthma

4.50

7.63

1.1

1.0

—

Asthma (diagnoses ohter than nonallergic)

3.00

7.58

1.0

—

Care involving use of rehabilitation procedures

3.43

7.57

1.0

—

Symptoms and signs involving the circulatory and respiratory systems

3.09

7.55

1.0

—

Migraine without aura

7.34

7.55

1.0

1.1

—

Hyperlipidaemia, other/unspecified

4.89

7.33

1.1

1.0

—

Myositis

+∞

7.30

1.1

0.0

—

Other joint disorders

3.28

7.30

1.0

—

Persons encountering health services for other counselling and medical advice, not elsewhere classified

2.78

7.20

1.0

—

Disorders of muscles

20.04

7.13

1.1

1.0

—

Abnormalities of gait and mobility

20.04

7.13

1.1

1.0

—

Persons encountering health services for specific procedures and health care

2.72

7.12

1.0

—

Autoimmune diseases

2.80

7.03

1.0

—

Used for control exclusion in common control thyroid runs

2.89

6.83

1.0

—

Depression medications

5.75

6.63

1.0

—

ILD medications: immunosuppressive drugs

3.34

6.49

1.0

—

Deforming dorsopathies

5.20

6.48

1.0

—

Diseases of the respiratory system

3.76

6.44

1.0

—

Acute upper respiratory infections of multiple and unspecified sites

3.04

6.39

1.0

—

Other headache syndromes

4.05

6.34

1.0

—

Second line medication for Crohn's disease

3.16

6.27

1.0

—

Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified

5.79

6.24

1.0

—

Excessive, frequent and irregular menstruation

4.95

6.07

1.0

1.1

—

Persons encountering health services for examination and investigation

3.80

6.01

1.0

—

Persons with potential health hazards related to communicable diseases

3.72

5.99

1.0

—

Abnormal findings on examination of blood, without diagnosis

3.74

5.95

1.1

1.0

—

Contact with and exposure to communicable diseases

3.99

5.85

1.0

—

Benign neoplasms

2.83

5.80

1.0

—

Benign neoplasms

2.64

5.77

1.0

—

Arthropathies

2.94

5.75

1.0

—

Oedema, not elsewhere classified

4.98

5.69

1.0

—

Nausea and vomiting

5.41

5.67

1.0

—

COPD differential diagnosis

2.96

5.62

1.0

—

ILD differential diagnosis

2.96

5.62

1.0

—

Pain in throat and chest

2.90

5.60

1.0

—

Asthma-related infections

3.18

5.54

1.0

—

Asthma, hospital admission 2, infections

3.18

5.54

1.0

—

Autoimmune diseases excluding thyroid diseases

2.62

5.53

1.0

—

Gastrointestinal diseases

3.39

5.44

1.0

—

Tramadol

3.09

5.40

1.0

—

Diseases of vocal cords and larynx+other diseases of upper respiratory tract, no elsewhere classified

3.12

5.37

1.0

—

Systemic connective tissue disorders

3.72

5.36

1.1

1.0

—

Factors influencing health status and contact with health services

11.04

5.29

1.0

—

Mood disorders, excluding more controls

2.54

5.23

1.0

—

Injury, poisoning and certain other consequences of external causes

3.51

5.21

1.0

—

Triptan medication for migraine, min. 3 purchases

2.98

5.18

1.0

—

Disorders of other endocrine glands

3.34

5.15

1.0

—

Recurrent or chronic depression

3.85

5.11

1.0

—

Other functional intestinal disorders

3.45

5.05

1.0

—

L04AX Other immunosuppressants

2.90

5.01

1.0

—

Excluding asthma or asthma-COPD overlap

2.81

4.99

1.0

—

Other pulmonary diagnosis

2.81

4.99

1.0

—

Acetic acid derivatives and related substances

7.82

4.97

1.0

—

Antihypertensive medication - note that there are other indications

3.28

4.92

1.0

—

Lower back pain or/and sciatica

2.38

4.91

1.0

—

Diarrhoea and gastroenteritis of presumed infectious origin

2.67

4.84

1.0

—

Spinal stenosis

3.79

4.82

1.0

—

Autoimmune diseases excluding thyroid diseases, strict definition

2.54

4.80

1.0

—

Disorders of lipoprotein metabolism and other lipidaemias

2.63

4.79

1.0

—

Migraine with aura

5.00

4.77

1.0

1.1

—

Fitting and adjustment of other devices

4.03

4.75

1.0

—

Lumbar disc prolapse

3.15

4.71

1.1

1.0

—

Hypertensive diseases (excluding secondary)

2.85

4.63

1.0

—

Psychiatric diseases

2.32

4.62

1.0

—

Any mental disorder

2.32

4.62

1.0

—

Bronchitis

2.32

4.61

1.0

—

Acute upper respiratory infections

2.39

4.54

1.0

—

Implicit Sepsis

2.75

4.54

1.0

—

3.18

4.54

1.1

1.0

—

Carpal tunnel syndrome

2.91

4.52

1.0

—

Coxarthrosis [arthrosis of hip](FG)

3.18

4.42

1.0

—

Other noninfective gastroenteritis and colitis

4.23

4.34

1.0

—

Migraine without aura and triptan purchases

4.55

4.30

1.0

—

Diseases of the eye and adnexa

2.46

4.27

1.0

—

COPD/asthma related infections

2.33

4.19

1.0

—

COPD/asthma/ILD related infections

2.33

4.19

1.0

—

Symptoms and signs involving the digestive system and abdomen

2.36

4.18

1.0

—

Hypertrophy of breast

4.35

4.08

1.0

—

Hypothyroidism, strict autoimmune

2.78

4.07

1.0

—

Coxarthrosis

3.29

4.07

1.0

—

Mood [affective] disorders

2.22

4.06

1.0

—

Headache

2.84

4.05

1.0

—

Migraine, single triptan purchase ok & required. ICD-code if available is included

2.37

4.03

1.0

—

Triptan medication for migraine, single purchase ok

2.37

4.03

1.0

—

Family history of certain disabilities and chronic diseases leading to disablement

10.03

4.01

1.0

—

Mood disorders

2.19

3.96

1.0

—

2.23

3.92

1.0

—

Oxycodone

4.21

3.89

1.0

—

Diseases of the skin and subcutaneous tissue

2.24

3.87

1.0

—

Other disorders of fluid, electrolyte and acid-base balance

4.19

3.87

1.0

—

Noninfective enteritis and colitis

2.77

3.83

1.0

—

Anxiety disorders, excluding more controls

2.36

3.83

1.0

—

Sciatica+with lumbago

3.24

3.83

1.1

1.0

—

Depression

2.20

3.82

1.0

—

Hypertrophy of breast in women and men

3.80

1.0

—

Fever of other and unknown origin

3.09

3.79

1.1

1.0

—

Procreative management

3.28

3.78

1.0

—

Abnormalities of heart beat

3.76

3.74

1.1

1.0

—

Hypothyroidism, strict autoimmune, 3 medication purchases required

2.37

3.63

1.0

—

Follow-up examination after treatment for conditions other than malignant neoplasms

3.74

3.60

1.0

—

Hypertensive diseases

2.25

3.59

1.0

—

Hypertension

2.25

3.59

1.0

—

Cardiovascular diseases

2.66

3.58

1.0

—

Lateral epicondylitis

7.79

3.55

1.0

—

Undetermined asthma, excluding more controls

7.78

3.55

1.0

—

Undetermined asthma

7.78

3.55

1.0

—

Persons with potential health hazards related to family and personal history and certain conditions influencing health status

2.19

3.54

1.0

—

Injury of eye and orbit

5.30

3.50

1.0

1.1

—

Intestinal infectious diseases

100

2.18

3.49

1.0

—

Haemorrhage from respiratory passages

3.87

3.47

1.0

—

Hypothyroidism, levothyroxine purchases

4.43

3.46

1.0

—

Hypothyroidism and >3 levothyroxin purchases

4.43

3.46

1.0

—

Hypothyroidism (congenital or acquired)

4.42

3.45

1.0

—

Benign neoplasm of colon, rectum, anus and anal canal

2.56

3.45

1.1

1.0

—

Polyarthropathies

2.73

3.41

1.0

—

Cough

3.29

3.37

1.0

—

Injuries to the head

101

2.06

3.37

1.0

—

Impingement syndrome of shoulder

7.00

3.36

1.0

—

Paroxysmal tachycardia

3.84

3.36

1.1

1.0

—

Asthma-related pneumonia

3.70

3.34

1.1

1.0

—

Asthma, hospital admissions 3, pneumonia

3.70

3.34

1.1

1.0

—

Asthma-related pneumonia or sepsis

3.70

3.34

1.1

1.0

—

Arthrosis

2.62

3.34

1.0

—

Temporomandibular joint disorders, including avohilmo

2.83

3.34

1.0

—

Non-allergic asthma (mode)

6.94

3.34

1.1

1.0

—

Non-allergic asthma (mode), excluding more controls

6.94

3.34

1.1

1.0

—

ILD medications: azathioprine

5.72

3.34

1.1

1.0

—

Autoimmune diseases related-to ILD

105

2.18

3.33

1.0

—

Irritable bowel syndrome

3.44

3.33

1.0

—

Anaemias

5.44

3.32

1.0

—

Benzodiazepine use

103

2.07

3.27

1.0

—

Other diseases of intestines

2.04

3.21

1.0

—

Azathioprine

5.34

3.19

1.1

1.0

—

Soft tissue disorders related to use, overuse and pressure

6.37

3.18

1.0

—

Heart failure, not strict

2.30

3.17

1.0

—

Ovarian cyst

3.74

3.17

1.0

1.1

—

Selective serotonin reuptake inhibitors

2.17

3.16

1.0

—

Abdominal and pelvic pain

2.14

3.15

1.0

—

Disorders of eyelid, lacrimal system and orbit

2.21

3.14

1.0

—

Other diseases of upper respiratory tract

2.07

3.14

1.0

—

Acute bronchitis

2.96

3.13

1.1

1.0

—

Hypertension, essential

2.17

3.12

1.0

—

Gonarthrosis

2.65

3.12

1.0

—

Benign neoplasm: Colon

2.61

3.09

1.1

1.0

—

Cardiovascular diseases (excluding rheumatic etc)

2.35

3.05

1.0

—

Abnormal involuntary movements

7.51

3.05

1.0

—

Adhesive capsulitis of shoulder

7.51

3.05

1.0

—

Benign neoplasm: Sigmoid colon

5.00

3.05

1.1

1.0

—

Dizziness and giddiness

2.26

3.04

1.0

—

Genitourinary diseases

2.51

3.02

1.0

—

Male infertility

10.02

2.98

1.0

—

Extrapyramidal and movement disorders

3.00

2.96

1.0

—

Deviated nasal septum

3.00

2.96

1.0

—

Other arthrosis

2.86

2.96

1.0

—

Other cataract

2.70

2.93

1.1

1.0

—

Hypothyreosis and Thyroxine purchase for inclusion criteria

2.14

2.93

1.0

—

Ulcerative colitis, NAS

4.71

2.91

1.0

1.1

—

Other degenerative diseases of the nervous system

7.58

2.91

1.0

—

Hypermobility syndrome

6.68

2.87

1.0

—

Noninfectious colitis NAS

5.39

2.86

1.0

1.1

—

Other symptoms and signs involving the digestive system and abdomen

5.39

2.86

1.1

1.0

—

Hypokalaemia

6.67

2.86

1.0

—

Other sleep disorders

6.67

2.86

1.0

1.1

—

Inflammatory bowel disease

2.93

2.85

1.0

—

Syncope and collapse

3.14

2.85

1.0

—

Hyperparathyroidism

5.32

2.84

1.0

1.1

—

Cardiac arrhythmias

2.32

2.81

1.1

1.0

—

Ischemic heart diseases

2.15

2.80

1.0

—

Osteopathies and chondropathies

2.41

2.79

1.0

—

Benign neoplasm: Sigmoid colon

4.45

2.79

1.1

1.0

—

Other and unspecified dermatitis

2.46

2.78

1.0

—

Hypothyroidism, other/unspecified

2.11

2.73

1.0

—

Brachial plexus disorders

5.01

2.72

1.0

—

Lesion of ulnar nerve

5.00

2.72

1.1

1.0

—

Diseases of liver

2.71

1.0

—

Gastro-oesophageal reflux disease

2.16

2.70

1.0

—

Symptoms and signs involving the skin and subcutaneous tissue

2.19

2.69

1.1

1.0

—

Disturbances of skin sensation

2.97

2.69

1.0

—

Symptoms and signs involving cognition, perception, emotional state and behaviour

100

1.96

2.68

1.0

—

Condition for Implicit Sepsis (Organ dysfunction codes)

2.08

2.68

1.0

—

Benign neoplasm: Rectum, anus and anal canal

4.21

2.67

1.0

—

Benign neoplasm: Rectum, anus and anal canal

4.21

2.67

1.0

1.1

—

Noninflammatory disorders of female genital tract

3.18

2.67

1.0

1.1

—

Disorders of breast

2.48

2.62

1.0

—

Other reaction to severe stress, and adjustment disorders

2.65

2.62

1.1

1.0

—

Mucosal proctocolitis

4.67

2.59

1.0

—

Neurotic, stress-related and somatoform disorders

1.96

2.59

1.0

—

Heart failure,strict

2.89

2.59

1.1

1.0

—

Benign lipomatous neoplasm

2.90

2.58

1.0

—

Use of pramipexole

3.60

2.57

1.0

—

Other disorders of the musculoskeletal system and connective tissue

4.00

2.56

1.1

1.0

—

Cervicalgia

4.00

2.56

1.0

—

Disorders of the thyroid gland

2.02

2.55

1.0

—

Anxiety disorders

1.93

2.50

1.0

—

Benign neoplasm: Rectum

4.38

2.47

1.0

—

Disorders of parathyroid gland

4.32

2.44

1.0

1.1

—

Polymyalgia rheumatica

5.00

2.40

1.2

1.0

—

Vocal cord dysfunction

5.07

2.39

1.0

—

Trigger finger

6.25

2.37

1.0

—

Hypopituitarism

6.26

2.37

1.0

—

Chronic rhinitis, nasopharyngitis and pharyngitis

2.75

2.37

1.0

—

Chronic sinusitis

2.41

2.36

1.0

—

Benign neoplasm: Rectum

4.12

2.36

1.0

1.1

—

Paracetamol of NSAID medication

6.05

2.35

1.0

—

Oxicams

5.69

2.34

1.0

—

Other heart diseases

2.35

2.34

1.1

1.0

—

Injuries to the ankle and foot

2.01

2.30

1.0

—

Diseases of oesophagus, stomach and duodenum

100

1.82

2.29

1.0

—

Heart failure and antihypertensive medication

3.78

2.29

1.1

1.0

—

Disorders of lens

2.07

2.29

1.0

—

Certain infectious and parasitic diseases

1.90

2.29

1.0

—

Irregular menses

2.34

2.28

1.0

—

Female genital prolapse

3.46

2.28

1.0

1.1

—

Other/unspecified dorsalgia

2.84

2.28

1.0

—

Benign lipomatous neoplasm

2.68

2.27

1.0

—

Neoplasms

2.02

2.27

1.0

—

Heartburn

4.62

2.27

1.0

—

Leisure time condition

3.48

2.26

1.0

—

Other and unspecified nerve root and plexus disorders, also in other diseases

3.48

2.26

1.0

—

Other extrapyramidal and movement disorders in other diseases

3.48

2.26

1.0

—

Benign neoplasm: Colon, unspecified

3.48

2.26

1.1

1.0

—

5-aminosalicylic acid

3.48

2.26

1.0

—

Other specified/unspecified arthritis

3.48

2.26

1.0

—

Presence of other functional implants

2.36

2.26

1.0

—

Ulcerative colitis

3.11

2.22

1.0

—

Other arthritis (FG)

3.10

2.22

1.0

—

Dermatitis and eczema

105

1.81

2.22

1.0

—

Postpartum hemorraghe, all women as controls

3.09

2.21

1.0

—

Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism

100

1.86

2.21

1.0

—

Umbilical hernia

2.78

2.20

1.0

—

Propionic acid derivatives

4.40

2.19

1.0

—

Anti-inflammatory and antirheumatic products, non-steroids

4.40

2.19

1.0

—

Disorders of lacrimal system

2.50

2.18

1.0

—

Benign neoplasm: Colon

2.23

2.18

1.1

1.0

—

Diseases of oral cavity, salivary glands and jaws

1.95

2.16

1.0

—

Type 2 diabetes

1.83

2.16

1.0

—

Atrial fibrillation and flutter with reimbursement

3.21

2.16

1.1

1.0

—

Diabetes mellitus

1.80

2.15

1.0

—

Atrial fibrillation and flutter

2.61

2.15

1.1

1.0

—

Dentofacial anomalies [including malocclusion]

2.97

2.11

1.0

—

Type of accident

2.70

2.10

1.0

—

Persons encountering health services in other circumstances

2.70

2.09

1.0

—

Polyneuropathies and other disorders of the peripheral nervous system

3.20

2.09

1.0

—

Dermatitis

2.13

2.08

1.0

—

Dermatitis due to substances taken internally

5.01

2.07

1.2

1.0

—

Cervicocranial syndrome

5.00

2.07

1.0

—

Polyarthrosis

4.11

2.07

1.0

1.1

—

Spondylolisthesis/Spondylolysis

3.50

2.05

1.0

—

Other neurological diseases

2.04

2.01

1.0

—

Postmenopausal bleeding

3.38

2.01

1.0

1.1

—

Female infertility

3.29

2.01

1.0

1.1

—

Supplementary factors related to causes of morbidity and mortality classified elsewhere

2.63

2.00

1.0

—

Intracranial injury

2.16

2.00

1.0

—

Any reimbursement code in KELA

2.18

2.00

1.0

—

Artrosis, including avohilmo

1.91

2.00

1.0

—

Benign neoplasm: Colon, unspecified

3.06

2.00

1.1

1.0

—

IBD patients in KELA-register

2.81

2.00

1.0

—

Other nutritional deficiencies

2.00

1.98

1.1

1.0

—

Benign neoplasm of colon, rectum, anus and anal canal

2.04

1.98

1.1

1.0

—

Abnormal serum enzyme levels

2.78

1.96

1.0

—

Migraine with aura and triptan purchases

3.34

1.96

1.0

—

Other and unspecified polyneuropathies, also in other diseases

3.34

1.96

1.0

—

Vasomotor and allergic rhinitis

2.37

1.96

1.1

1.0

—

Reimbursement for rheumatic diseases

2.07

1.95

1.0

—

Melanocytic naevi, other sites/unspecified

4.55

1.94

1.0

—

Suggestive for eosinophilic asthma

4.55

1.94

1.0

—

Benign neoplasm: Ascending colon

4.55

1.94

1.2

1.0

—

Other disorders of lacrimal gland

2.57

1.92

1.0

—

Coxarthrosis, primary

2.13

1.91

1.0

—

Gonarthrosis [arthrosis of knee](FG)

2.00

1.90

1.0

—

All-cause Heart Failure

2.40

1.90

1.1

1.0

—

Other abnormal uterine and vaginal bleeding

3.89

1.89

1.0

1.1

—

Postpartum hemorraghe, parous women as controls

2.72

1.89

1.0

—

Diabetes medication

1.74

1.88

1.0

—

Postpartum haemorrhage

2.70

1.87

1.0

—

Constipation

1.85

1.87

1.0

—

Pain and other conditions associated with female genital organs and menstrual cycle

4.36

1.87

1.0

1.1

—

Female infertility, cervigal, vaginal, other or unspecified origin

3.35

1.86

1.0

1.1

—

Inflammatory bowel disease, strict (require KELA)

2.65

1.86

1.0

—

Coxibs

3.99

1.83

1.0

—

Intrahepatic Cholestasis of Pregnancy (ICP) , incl. ICD-8

4.17

1.82

1.0

—

Benign neoplasm: Ascending colon

4.17

1.82

1.2

1.0

—

External causes of morbidity and mortality

1.98

1.80

1.1

1.0

—

Ulcerative colitis (strict definition, require KELA, min 2 HDR)

3.05

1.80

1.0

—

Postmenopausal atrophic vaginitis

3.24

1.77

1.0

1.1

—

Cystitis

1.86

1.76

1.0

—

Ischaemic heart disease, wide definition

1.85

1.75

1.0

—

Inflammatory disease of uterus

3.34

1.74

1.0

1.1

—

Somatoform disorder

3.34

1.74

1.0

—

Other acute lower respiratory infections

2.09

1.74

1.1

1.0

—

Papulosquamous disorders

2.22

1.73

1.0

—

Coronary revascularization (ANGIO or CABG)

2.40

1.73

1.0

—

Ulcerative colitis (strict definition, require KELA)

2.92

1.72

1.0

—

Other (not insulin) diabetes medications

1.72

1.0

—

Melanocytic naevi, other sites/unspecified

3.85

1.71

1.0

—

Dental pulpitis 4, only avohilmo

1.68

1.71

1.0

—

Other inflammation of eyelid

3.85

1.71

1.0

1.1

—

Radiculopathy

3.85

1.71

1.0

—

Heart failure, strict

2.27

1.71

1.1

1.0

—

Mouth breathing

2.13

1.71

1.0

—

Endometriosis

2.80

1.69

1.0

1.1

—

Hard cardiovascular diseases

1.82

1.68

1.0

—

Continuous positive airway pressure

3.24

1.66

1.0

—

Abnormal findings in secretions and smears from cervix uteri vagina vulva

2.08

1.66

1.0

—

Dysphagia

3.16

1.66

1.0

—

Other disorders of bone

2.58

1.65

1.0

—

Fracture of foot, except ankle

2.58

1.65

1.0

—

Pure hypercholesterolaemia

1.93

1.63

1.1

1.0

—

Other heart diseases, wide

1.70

1.62

1.0

—

Intrahepatic Cholestasis of Pregnancy (ICP) , incl. ICD-8, excluding more controls

3.57

1.61

1.0

—

Bitten or struck by other mammals

3.57

1.61

1.0

—

Obesity due to excess calories

2.06

1.59

1.1

1.0

—

Injuries to the wrist and hand

108

1.68

1.58

1.0

—

Ulcerative colitis (strict definition, all Crohn cases excluded)

3.00

1.58

1.0

—

Chronic diseases of tonsils and adenoids

1.77

1.56

1.0

—

Emergency coronary revascularization (for ACS)

2.26

1.55

1.0

—

Other hearing loss

2.95

1.55

1.0

1.1

—

Diabetes, varying definitions

1.65

1.54

1.0

—

Senile cataract

1.95

1.54

1.1

1.0

—

Major coronary heart disease event

1.89

1.54

1.1

1.0

—

Diplopia

3.34

1.52

1.2

1.0

—

Pain in thoracic spine

3.33

1.52

1.0

—

Disorders of vestibular function (Vertigo)

2.09

1.52

1.0

—

Exclusions for E4_PCOS_BROAD

2.59

1.51

1.0

—

Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk

2.86

1.50

1.0

—

Nasal polyp

2.86

1.50

1.0

—

Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified (FINNGEN)

2.02

1.49

1.0

—

Coronary angioplasty

2.47

1.48

1.0

—

Coronary atherosclerosis

1.86

1.47

1.1

1.0

—

Glucagon-like peptide-1 (GLP-1) analogues

2.02

1.46

1.1

1.0

—

Infections with a predominantly sexual mode of transmission

2.22

1.46

1.0

—

UC patients in KELA-register ( KELA 208 prior to 1994, or ICD K51)

2.50

1.45

1.0

—

Meniscus derangement

2.11

1.44

1.0

—

Disorders of sclera, cornea, iris and ciliary body

1.88

1.44

1.0

—

Dental pulpitis 1, only avohilmo

1.61

1.44

1.0

—

Other disorders of breast

3.13

1.44

1.0

1.1

—

Cardiomyopathy (excluding other)

3.13

1.44

1.0

—

Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk

2.73

1.43

1.0

—

Abnormal findings on diagnostic imaging and in function studies, without diagnosis

1.88

1.43

1.1

1.0

—

Persons encountering health services in circumstances related to reproduction

1.79

1.42

1.0

—

Non-ischemic cardiomyopathy

2.50

1.42

1.0

—

Non-invasive ventilation

2.68

1.40

1.0

—

Other diseases of liver

2.42

1.39

1.0

—

Disorders of conjunctiva

1.69

1.36

1.0

—

Restless leg syndrome

2.94

1.36

1.0

1.1

—

Cardiomyopathies, Primary/intrinsic

2.94

1.36

1.0

—

Diseases of salivary glands

2.94

1.36

1.0

—

Type 2 diabetes, strict (exclude DM1)

1.63

1.34

1.0

—

Type 2 diabetes, definitions combined

1.63

1.34

1.0

—

Bacterial Sepsis

2.16

1.34

1.0

—

Acute sinusitis

1.92

1.33

1.0

—

Symptoms and signs involving speech and voice

2.14

1.33

1.0

—

Other arrhythmias

1.80

1.32

1.0

—

Allergic rhinitis

2.12

1.32

1.0

—

Iron deficiency anaemia

2.12

1.32

1.0

—

Type 2 diabetes, definitions combined, including avohilmo

1.61

1.31

1.0

—

Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis

1.83

1.31

1.0

—

Myocardial infarction, without ST-elevation

2.38

1.30

1.1

1.0

—

Open wound of wrist and hand

1.95

1.29

1.0

—

Polycystic ovarian syndrome, consortium definition

1.77

1.27

1.0

—

Type 2 diabetes, wide definition

1.70

1.26

1.1

1.0

—

Dysplasia of cervi uteri

2.76

1.24

1.0

1.1

—

Developmental endpoint to exclude non autoimmune-cases from E4_HYTHY_AI_STRICT

2.00

1.23

1.0

—

Cirrhosis, broad definition used in the article https://doi.org/10.1101/594523

2.63

1.21

1.0

1.1

—

Acute renal failure

2.63

1.21

1.0

1.1

—

Other disorders of skin and subcutaneous tissue, not elsewhere classified

2.63

1.21

1.2

1.0

—

Accidents

1.62

1.19

1.0

—

Other external causes of accidental injury

1.62

1.19

1.0

—

Nutritional anaemias

1.95

1.18

1.0

—

Injuries to the knee and lower leg

106

1.51

1.18

1.0

—

Internal derangement of knee

2.10

1.18

1.0

—

Polyp of the female genital tract

2.55

1.17

1.0

1.1

—

Maternal care related to the fetus and amniotic cavity and possible delivery problems

1.83

1.17

1.0

—

Dental pulpitis 4

1.53

1.15

1.0

—

Covid-19 confirmed case

2.05

1.15

1.0

—

Diseases of the ear and mastoid process

1.50

1.15

1.0

—

Cholelithiasis

1.61

1.14

1.0

—

Dental operations

1.75

1.13

1.1

1.0

—

Gonarthrosis,primary

1.59

1.12

1.0

—

Blepharochalasis

2.33

1.12

1.0

—

Contraceptive management

1.87

1.11

1.0

—

Diseases of inner ear

1.84

1.11

1.0

—

Dental pulpitis 1

1.52

1.10

1.0

—

Diseases of male genital organs

1.82

1.10

1.0

—

Diseases of pulp and periapical tissues, including avohilmo

1.52

1.10

1.0

—

Other disorders of ear

1.56

1.10

1.0

—

Inflammatory diseases of female pelvic organs

1.76

1.09

1.0

—

Menorrhagia

2.28

1.09

1.0

1.1

—

Chronic periapical parodontitis

2.38

1.09

1.0

—

Calculus of kidney and ureter

1.95

1.08

1.0

—

Urolithiasis

1.95

1.08

1.0

—

Other predominantly sexually transmitted diseases, not elsewhere classified

2.19

1.08

1.0

—

Sequelae of cerebrovascular disease

2.19

1.08

1.0

—

Obesity

1.69

1.07

1.1

1.0

—

Obesity and other hyperalimentation

1.69

1.07

1.1

1.0

—

Postpartum care and examination

2.45

1.07

1.0

—

Diabetes, insuline treatment (Kela reimbursement), excluding more controls

1.53

1.04

1.0

—

Other disorders of eyelid

1.98

1.04

1.0

—

Other symptoms and signs involving cognitive functions and awareness

1.96

1.03

1.0

—

Seborrhoeic keratosis

2.27

1.03

1.0

—

Cardiomyopathy

2.27

1.03

1.0

—

Keratitis

1.96

1.03

1.0

—

Other and unspecified iron deficiency

2.06

1.02

1.0

—

Coxarthrosis, primary, with hip surgery

1.90

1.01

1.0

—

Allergic asthma (mode)

2.23

1.01

1.0

—

Allergic asthma (mode), excluding more controls

2.23

1.01

1.0

—

Other benign neoplasms of skin

1.88

1.00

1.0

—

Examination and observation for other reasons

1.89

1.00

1.0

—

Type 1 diabetes

2.00

0.99

1.0

—

Pacemaker

2.21

0.99

1.0

—

Other menopausal disorders

2.47

0.98

1.0

1.1

—

Hernia of abdominal wall

1.80

0.98

1.0

—

Lichen planus, including avohilmo

2.17

0.98

1.0

—

Other diseases of urinary system

1.50

0.98

1.0

—

Cholelithiasis, broad definition with cholecystitis

1.54

0.97

1.0

—

Psoriasis

1.94

0.97

1.0

—

Disorders of refraction and accommodation

1.94

0.96

1.0

—

Rheumatoid arthritis

2.27

0.94

1.0

—

Other benign neoplasms of skin

1.77

0.94

1.0

—

Hernia

100

1.49

0.94

1.0

—

Abnormal findings on diagnostic imaging of lung

1.84

0.94

1.1

1.0

—

Use of eye-antiallergens (taken as indicator of allergic/atopic conjunctivitis)

1.68

0.93

1.0

—

Gingivitis and periodontal diseases

1.56

0.92

1.1

1.0

—

Dislocation, sprain and strain of joints and ligaments at ankle and foot level

1.73

0.92

1.0

—

Conjunctivitis

1.56

0.91

1.0

—

Corneal ulcer

2.14

0.91

1.0

—

Lichen ruber planus, wide definition including periferal and oral lichen planus

2.14

0.91

1.0

—

Pollen allergy

2.12

0.91

1.0

—

Maternal care for other conditions predominantly related to pregnancy

2.11

0.90

1.0

—

Other maternal disorders predominantly related to pregnancy

1.66

0.90

1.0

—

Other diseases of blood and blood-forming organs, wide

2.07

0.89

1.2

1.0

—

Fissure and fistula of anal and rectal regions

2.07

0.89

1.0

—

Conduction disorders

2.08

0.89

1.0

—

False labour

1.86

0.87

1.0

—

Iridocyclitis

2.00

0.87

1.0

—

Benign paroxysmal vertigo

2.00

0.87

1.0

—

Chronic gastritis

2.00

0.87

1.0

—

Non-selective monoamine reuptake inhibitors

1.85

0.86

1.0

—

Fracture at wrist and hand level

1.82

0.85

1.0

—

Hallux valgus (acquired)

1.97

0.85

1.0

—

Disorders of gallbladder, biliary tract and pancreas

1.45

0.82

1.0

—

Implicit bacterial Sepsis

1.90

0.82

1.0

—

Haemorrhoids and perianal venous thrombosis

1.87

0.81

1.0

—

Unstable angina pectoris

1.84

0.79

1.2

1.0

—

Injuries to the thorax

1.72

0.79

1.0

—

Diabetes, insulin treatment (Kela reimbursement)

1.42

0.79

1.0

—

Mycoses

1.82

0.79

1.0

—

Cardiodefibrillation

1.82

0.79

1.0

—

Schizophrenia

0.00

0.77

0.0

1.0

—

Biguanides

1.44

0.77

1.0

—

Allergic conjunctivitis

1.58

0.76

1.0

—

Superficial injury of lower leg

1.77

0.76

1.0

—

Gonarthrosis, primary, with knee surgery

1.66

0.76

1.0

—

Actinic keratosis

2.16

0.76

1.0

—

Dislocation, sprain and strain of joints and ligaments at neck level

2.08

0.74

1.0

—

Enthesopathies of lower limb, excluding foot

2.08

0.74

1.0

—

Heart failure and coronary heart disease

2.07

0.74

1.2

1.0

—

Voice disturbances

1.84

0.73

1.0

—

Dislocation, sprain and strain of joints and ligaments at wrist and hand level

1.84

0.73

1.0

—

In situ neoplasms

1.84

0.73

1.0

—

Appendectomy

104

1.48

0.73

1.0

—

Chondropathies

2.00

0.72

1.0

—

Insomnia

2.00

0.72

1.0

—

Acute pancreatitis (for exclusion)

2.00

0.72

1.0

—

Cervicobrachial syndrome

2.00

0.72

1.0

—

Other disorders of skin and subcutaneous tissue

1.53

0.72

1.1

1.0

—

Renal failure

1.78

0.72

1.0

—

Complications of medical and surgical care

1.50

0.72

1.0

—

Sub-endpoint used in defining T1D endpoints

1.77

0.71

1.0

—

Other septicaemia

1.76

0.71

1.1

1.0

—

Melanocytic naevi

1.75

0.71

1.0

—

Explicit Sepsis

1.72

0.70

1.1

1.0

—

Skin changes due to chronic exposure to nonionizing radiation

1.89

0.69

1.0

—

Unspecified fall

1.54

0.69

1.0

—

Diabetes mellitus in pregnancy

1.68

0.68

1.0

—

Acute and subacute iridocyclitis

1.85

0.68

1.0

—

Acute pancreatitis

1.85

0.68

1.0

—

In situ neoplasms

1.67

0.68

1.0

—

Type 1 diabetes, wide definition, subgroup 1

1.85

0.68

1.0

—

Exposure to other specified factors

111

1.44

0.67

1.0

—

Septicaemia

1.64

0.67

1.1

1.0

—

Dental operations, only avohilmo

1.51

0.67

1.1

1.0

—

Melanocytic naevi

1.63

0.66

1.0

—

Other fall from one level to another

1.79

0.66

1.0

—

Behavioural syndromes associated with physiological disturbances and physical factors

1.59

0.65

1.0

—

Codes for special purposes

1.61

0.65

1.0

—

Provisional assignment of new diseases of uncertain etiology

1.61

0.65

1.0

—

Cholecystectomy

1.46

0.64

1.0

—

Medical treatment for female infertility

1.72

0.63

1.0

—

Dental caries 1 and operation codes

1.42

0.62

1.1

1.0

—

Insulin, fast-acting or short human

1.63

0.62

1.0

—

Insulin, fast-acting

1.63

0.62

1.0

—

Anterior Iridocyclitis

1.67

0.61

1.0

—

Diagnoses used for exclusion with ILD

1.67

0.61

1.0

—

Any mental disorder, or suicide (or attempt), or psychic disorders complicating pregnancy, partum or puerperum or nerve system disorders, excluding more controls

1.67

0.61

1.0

—

Type 1 diabetes, wide definition

1.67

0.61

1.0

—

Congenital malformations of the circulatory system

0.00

0.60

0.0

1.1

—

Viral and other specified intestinal infections

0.00

0.60

0.0

1.1

—

Myocardial infarction, with ST-elevation

0.00

0.60

0.0

1.0

—

Exclusions for E4_PCOS_CONSORTIUM

1.43

0.60

1.0

—

Striking against or struck by other objects

1.57

0.60

1.0

—

Malignant neoplasm of respiratory system and intrathoracic organs, excluding all cancers (controls excluding all cancers)

0.00

0.59

0.0

1.0

—

Delivery, wide proxy

1.77

0.59

1.0

1.1

—

Colectomy operation

0.00

0.59

0.0

1.0

—

D07AA Corticosteroids, weak (group I)

0.00

0.59

0.0

1.0

—

Gestational diabetes (for exclusion)

1.53

0.59

1.0

—

Appendicitis, broad definition

112

1.39

0.58

1.0

—

Injury of muscle and tendon at shoulder and upper arm level

1.48

0.57

1.0

—

Diseases of appendix

112

1.38

0.57

1.0

—

Acute appendicitis

108

1.40

0.57

1.0

—

COPD/asthma/ILD related pneumonia or pneumonia derived septicaemia

1.41

0.56

1.1

1.0

—

1.41

0.56

1.1

1.0

—

Conjunctivitis (acute, non atopic)

1.66

0.56

1.0

—

Haemorrhage in early pregnancy

1.63

0.55

1.0

—

Sensorineural hearing loss

1.42

0.55

1.0

—

Colonic or urogenital fistula

1.62

0.55

1.0

—

Localized swelling, mass and lump of skin and subcutaneous tissue

1.62

0.55

1.2

1.0

—

Functional dyspepsia

1.58

0.54

1.0

—

Other anxiety disorders

1.48

0.53

1.0

—

All dysplastic lesions of the cervix uteri, vagina or vulva

1.53

0.52

1.0

—

Dental caries 3

1.38

0.52

1.1

1.0

—

Viral infections characterized by skin and mucous membrane lesions

1.43

0.52

1.0

—

Degeneration of macula and posterior pole

1.50

0.51

1.0

—

Visual disturbances and blindness

1.41

0.51

1.1

1.0

—

Single spontaneous delivery

1.62

0.51

1.0

—

Medical abortion

1.44

0.50

1.0

—

Other retinal disorders

1.47

0.50

1.0

—

Symptoms and signs involving the urinary system

1.38

0.50

1.0

—

Renal tubulo-interstitial diseases

1.36

0.49

1.0

—

Disorders of ocular muscles, binocular movement, accommodation and refraction

1.48

0.48

1.0

—

STROKE

1.44

0.48

1.0

—

Chronic periodontitis, including avohilmo

107

1.31

0.47

1.1

1.0

—

Substance abuse, excluding more controls

1.48

0.47

1.0

—

Dental caries 3 and operation codes

1.34

0.47

1.1

1.0

—

Conductive and sensorineural hearing loss

1.35

0.47

1.0

—

Parodontitis and operation codes

106

1.32

0.47

1.1

1.0

—

Statin medication

1.34

0.46

1.1

1.0

—

Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified

100

1.30

0.46

1.0

—

Other and unspecified tonsillitis

1.45

0.46

1.0

—

Myocardial infarction, strict

1.42

0.45

1.0

—

Fall on same level

106

1.26

0.45

1.0

—

Parodontitis

108

1.30

0.44

1.1

1.0

—

Parodontitis or operation codes

108

1.30

0.44

1.1

1.0

—

Rheumatoid arthritis, including avohilmo

1.37

0.44

1.0

—

Obstructed labour due to malposition and malpresentation of fetus

1.62

0.43

1.0

—

Myocardial infarction

1.44

0.43

1.1

1.0

—

All influenza

1.61

0.43

1.2

1.0

—

Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure

1.41

0.43

1.0

—

Single delivery by forceps and vacuum extractor

0.00

0.43

0.0

1.0

—

HSIL lesion of the cervix uteri, vagina or vulva

1.56

0.42

1.0

—

Sequelae of external causes of morbidity and mortality

1.56

0.42

1.0

—

Complications of surgical and medical care, not elsewhere classified

106

1.29

0.42

1.0

—

Dental caries 3, only avohilmo

1.32

0.41

1.1

1.0

—

Malignant neoplasm of bronchus and lung

0.00

0.41

0.0

1.1

—

Sleep disorders

1.52

0.41

1.0

—

Injuries to the neck

1.52

0.41

1.0

—

Eustachian salpingitis and obstruction

0.00

0.41

0.0

1.0

—

Use of disulfiram, acamprosate or naltrexone

0.00

0.41

0.0

1.0

—

Sequelae of injuries of lower limb

0.00

0.41

0.0

1.0

—

Diseases of peritoneum

0.00

0.41

0.0

1.1

—

Contact with machinery

0.00

0.41

0.0

1.0

—

Seborrhoeic dermatitis

0.00

0.41

0.0

1.0

—

Ulcer of lower limb, not elsewhere classified

0.00

0.41

0.0

1.0

—

0.00

0.41

0.0

1.1

—

Secondary uncertain malignant neoplasm

0.00

0.40

0.0

1.1

—

Major coronary heart disease event excluding revascularizations

1.41

0.40

1.1

1.0

—

Visual disturbances

1.33

0.40

1.1

1.0

—

Maternal care for other known or suspected fetal problems

1.46

0.40

1.0

—

Graves disease, strict definition

0.00

0.40

0.0

1.1

—

Pedal cyclist injured in other and unspecified transport accidents

0.00

0.40

0.0

1.0

—

Toxic effects of substances chiefly nonmedicinal as to source

0.00

0.40

0.0

1.0

—

Poor fetal growth

0.00

0.40

0.0

1.0

—

Injury of muscle and tendon at wrist and hand level

0.00

0.40

0.0

1.0

—

Malignant neoplasm of respiratory system and intrathoracic organs

0.00

0.40

0.0

1.1

—

Malignant neoplasm of bronchus and lung, excluding all cancers (controls excluding all cancers)

0.00

0.39

0.0

1.0

—

1.43

0.39

1.0

—

Otitis externa, unspecified

0.00

0.39

0.0

1.1

—

Secondary and unspecified malignant neoplasm of lymph nodes, excluding all cancers (controls excluding all cancers)

0.00

0.39

0.0

1.0

—

Seropositive rheumatoid arthritis, strict definition

0.00

0.39

0.0

1.1

—

Panic disorder

0.00

0.39

0.0

1.0

—

Malignant neoplasm of colon, excluding all cancers (controls excluding all cancers)

0.00

0.39

0.0

1.0

—

Transient ischemic attack

1.36

0.38

1.0

—

Open wound of head

1.36

0.38

1.0

—

All dysplastic lesions of the cervix uteri

1.39

0.38

1.0

—

Artificial joint operation, meniscal resection

1.27

0.37

1.0

—

Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure

1.37

0.37

1.0

—

Spontaneous abortion

1.30

0.37

1.0

—

Falls/tendency to fall

1.24

0.37

1.0

—

Dental caries 2 and operation codes, only avohilmo

0.73

0.36

1.0

—

Insulin, intermediate and long-acting

1.26

0.36

1.1

1.0

—

Persons with potential health hazards related to socioeconomic and psychosocial circumstances

1.45

0.35

1.0

—

Delivery

1.38

0.35

1.0

—

Anxiety (asthma-related co-morbidities)

1.33

0.34

1.0

—

Diseases of pulp and periapical tissues

1.36

0.34

1.0

—

Congenital malformations, deformations and chromosomal abnormalities

1.32

0.34

1.0

—

Diaphragmatic hernia

1.33

0.33

1.0

—

Acute appendicitis, no complications

1.32

0.33

1.0

—

Dislocation, sprain and strain of joints and ligaments of knee

1.30

0.33

1.0

—

Leiomyoma of uterus

1.37

0.32

1.0

—

Obesity, other/unspecified

1.28

0.32

1.2

1.0

—

Dental caries 2

104

0.76

0.32

1.0

—

Diseases of the digestive system

1.29

0.30

1.0

—

Dental pulpitis 2, only avohilmo

1.28

0.30

1.1

1.0

—

Injuries to the elbow and forearm

1.28

0.30

1.0

—

Dental caries 2, only avohilmo

103

0.77

0.29

1.0

—

Atopic dermatitis

1.33

0.29

1.0

—

Infections of the skin and subcutaneous tissue

1.30

0.29

1.0

—

All anxiety disorders

1.29

0.28

1.0

—

Dental caries 2 and operation codes

103

0.77

0.28

1.0

—

Leiomyoma of uterus

1.29

0.27

1.0

—

Complications of labour and delivery

1.29

0.27

1.0

—

Basal cell carcinoma, including avohilmo, excluding all cancers (controls excluding all cancers)

0.67

0.26

1.0

—

Other malignant neoplasms of skin (=non-melanoma skin cancer), excluding all cancers (controls excluding all cancers)

0.66

0.26

1.0

—

Exposure to unspecified factor

116

1.20

0.26

1.0

—

Dental caries 1, only avohilmo

1.24

0.25

1.1

1.0

—

Alcohol use disorder, Swedish definition

1.28

0.25

1.0

—

Angina pectoris

1.22

0.25

1.1

1.0

—

Influenza and pneumonia

111

1.18

0.24

1.1

1.0

—

Malignant neoplasm of skin, excluding all cancers (controls excluding all cancers)

0.72

0.24

1.0

—

Stroke, including SAH

0.72

0.24

1.0

—

Erysipelas

0.74

0.24

1.0

—

Other and unspecified effects of external causes

1.32

0.23

1.0

—

Tonsillectomy and adenotomy

1.25

0.23

1.0

—

Pregnancy with abortive outcome

1.25

0.23

1.0

—

Heart failure and bmi 25plus

1.28

0.23

1.0

—

Preterm labour and delivery

1.25

0.22

1.0

—

Childhood allergy (age < 16)

0.00

0.21

0.0

1.0

—

Ankylosing spondylitis, strict definition

0.00

0.21

0.0

1.0

—

Other and unspecified coagulation defects

0.00

0.21

0.0

1.0

—

Presence of cardiac and vascular implants and grafts

1.18

0.21

1.0

—

Hypertrophic scar

0.00

0.21

0.0

1.0

—

Chronic viral hepatitis

0.00

0.21

0.0

1.0

—

Hypertrophic disorders of skin

0.00

0.21

0.0

1.0

—

Etanercept

0.00

0.21

0.0

1.0

—

Endovascular or surgical operations to intracerebral aneurysms

0.00

0.21

0.0

1.0

—

Benign neoplasm of brain and other parts of central nervous system

0.00

0.21

0.0

1.0

—

Event of undetermined intent

0.00

0.21

0.0

1.0

—

Foreign body or object entering through skin

0.00

0.21

0.0

1.0

—

Malignant neoplasm of eye, brain and central nervous system, excluding all cancers (controls excluding all cancers)

0.00

0.21

0.0

1.0

—

Anogenital herpesviral [herpes simplex] infection

0.00

0.21

0.0

1.0

—

Corns and callosities

0.00

0.21

0.0

1.0

—

Contact with other sharp object(s)

0.00

0.21

0.0

1.0

—

Chronic suppurative otitis media

0.00

0.21

0.0

1.0

—

Other follicular disorders

0.00

0.21

0.0

1.0

—

Care involving dialysis

0.00

0.21

0.0

1.0

—

Normotensive glaucoma

0.00

0.21

0.0

1.1

—

Benign neoplasm of middle ear and respiratory system

0.00

0.21

0.0

1.0

—

Use of antiglaucoma preparations and miotics

0.00

0.21

0.0

1.0

—

Chronic suppurative otitis media, including avohilmo

0.00

0.21

0.0

1.0

—

Other and/or unspecified nontoxic goitre

0.00

0.21

0.0

1.1

—

Other and unspecified vascular occlusions

0.00

0.21

0.0

1.1

—

Transient global amnesia

0.00

0.21

0.0

1.1

—

Intestinal adhesions without obstruction

0.00

0.21

0.0

1.1

—

Memory loss

0.00

0.21

0.0

1.1

—

Non-follicular lymphoma, hilmo, excluding all cancers

0.00

0.21

0.0

1.0

—

Benign neoplasm: Stomach

0.00

0.21

0.0

1.1

—

Benign neoplasm: Stomach

0.00

0.21

0.0

1.0

—

Other diseases of oesophagus

0.00

0.21

0.0

1.1

—

Colon adenocarcinoma, excluding all cancers (controls excluding all cancers)

0.00

0.21

0.0

1.0

—

Abnormal spermatozoa

0.00

0.21

0.0

1.0

—

Retinal vascular disorders

0.00

0.21

0.0

1.1

—

COPD-related respiratory insufficiency

0.00

0.21

0.0

1.0

—

Retinal vascular occlusion

0.00

0.21

0.0

1.1

—

Malignant neoplasm of bladder, excluding all cancers (controls excluding all cancers)

0.00

0.21

0.0

1.0

—

Macular pucker

0.00

0.21

0.0

1.1

—

0.00

0.21

0.0

1.1

—

Dental caries 3 and operation codes, only avohilmo

1.31

0.21

1.2

1.0

—

Exposure to other and unspecified inanimate mechanical forces

0.00

0.21

0.0

1.0

—

Benign neoplasm: Parotid gland

0.00

0.21

0.0

1.0

—

Benign neoplasm: Parotid gland

0.00

0.21

0.0

1.1

—

Otosclerosis

0.00

0.21

0.0

1.1

—

Other and unspecified injuries of lower leg

0.00

0.21

0.0

1.0

—

Secondary and unspecified malignant neoplasm of lymph nodes

0.00

0.21

0.0

1.0

—

Other puerperal infections

0.00

0.21

0.0

1.0

—

Allergic urticaria

0.00

0.21

0.0

1.0

—

Other diseases of biliary tract

0.00

0.21

0.0

1.1

—

Non-follicular lymphoma

0.00

0.21

0.0

1.1

—

Other and unspecified visual disturbances

0.00

0.21

0.0

1.0

—

Embedded teeth, including avohilmo

0.00

0.21

0.0

1.0

—

Enterocolitis due to Clostridium difficile

0.00

0.21

0.0

1.1

—

Peripheral artery operations in Hilmo

0.00

0.21

0.0

1.0

—

Eating disorder

0.00

0.21

0.0

1.0

—

Dental caries, including avohilmo

1.21

0.21

1.1

1.0

—

Dental caries 1

1.21

0.21

1.1

1.0

—

Other viral hepatitis

0.00

0.21

0.0

1.0

—

Benign neoplasm of middle ear and respiratory system

0.00

0.21

0.0

1.0

—

Conductive hearing loss, unspecified

0.00

0.21

0.0

1.1

—

Mental disorders, not otherwise specified

0.00

0.21

0.0

1.0

—

Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure

0.00

0.21

0.0

1.0

—

Other and unspecified local infections of skin and subcutaneous tissue

0.00

0.21

0.0

1.0

—

Benign neoplasm of major salivary glands

0.00

0.21

0.0

1.0

—

Twin gestation

0.00

0.21

0.0

1.0

—

Infectious mononucleosis

0.00

0.21

0.0

1.0

—

Malignant melanoma of skin

0.00

0.21

0.0

1.1

—

Abnormalities of forces of labour

0.00

0.21

0.0

1.0

—

Colon adenocarcinoma

0.00

0.21

0.0

1.1

—

Pleural effusion

0.00

0.21

0.0

1.1

—

Intracerebral haemorrhage

0.00

0.21

0.0

1.1

—

Hypotension

0.00

0.21

0.0

1.1

—

Eating disorders

0.00

0.21

0.0

1.0

—

Non-small cell lung cancer, excluding all cancers (controls excluding all cancers)

0.00

0.20

0.0

1.0

—

Nummular dermatitis

0.00

0.20

0.0

1.0

—

Schizoaffective disorder

0.00

0.20

0.0

1.0

—

Benign neoplasm: salivary glands, exclude unknown (D119)

0.00

0.20

0.0

1.1

—

Benign neoplasm of major salivary glands

0.00

0.20

0.0

1.1

—

Vitreous haemorrhage

0.00

0.20

0.0

1.1

—

Glomerulonephritis

0.00

0.20

0.0

1.0

—

Multiple gestation

0.00

0.20

0.0

1.0

—

Other local infections of skin and subcutaneous tissue

0.00

0.20

0.0

1.0

—

Non-Hodgkin lymphoma, all, excluding all cancers (controls excluding all cancers)

0.00

0.20

0.0

1.0

—

Benign mammary dysplasia

0.00

0.20

0.0

1.1

—

Malignant neoplasm of colon

0.00

0.20

0.0

1.1

—

Non-small cell lung cancer

0.00

0.20

0.0

1.1

—

Endometriosis of ovary

0.00

0.20

0.0

1.1

—

Unspecified haematuria

1.20

0.19

1.0

—

Injuries to the hip and thigh

1.19

0.19

1.0

—

Other disorders of urethra and urinary system

1.23

0.19

1.0

—

DVT of lower extremities and pulmonary embolism

1.17

0.19

1.0

—

Parodontitis or/and operation codes

1.21

0.19

1.1

1.0

—

Dental pulpitis 2

1.21

0.19

1.1

1.0

—

Urticaria and erythema

1.13

0.18

1.0

—

Diverticular disease of intestine

1.21

0.18

1.0

—

Basal cell carcinoma

0.74

0.17

1.0

—

Primary gonarthrosis, bilateral

1.11

0.17

1.0

—

Transport accidents

0.71

0.17

1.0

—

Mental and behavioural disorders due to alcohol, excluding acute intoxication

0.72

0.16

1.0

—

Malignant neoplasm of breast, HER2-negative

1.13

0.16

1.1

1.0

—

Bleeding

1.17

0.16

1.0

—

Malignant neoplasm of breast, HER2-negative, excluding all cancers (controls excluding all cancers)

1.11

0.16

1.1

1.0

—

Malignant neoplasm of breast, excluding all cancers (controls excluding all cancers)

1.11

0.16

1.1

1.0

—

Venous thromboembolism

1.13

0.16

1.0

—

Complications of procedures, not elsewhere classified

104

1.16

0.15

1.0

—

Mental and behavioural disorders due to alcohol

0.76

0.15

1.0

—

Acute tubulo-interstitial nephritis

1.14

0.15

1.0

—

Insulin medication

1.13

0.15

1.1

1.0

—

Insulin, combination of fast acting with intermediate-acting or long-acting

1.09

0.14

1.1

1.0

—

Malignant neoplasm

1.14

0.14

1.1

1.0

—

Other diseases of hard tissues of teeth

1.20

0.14

1.0

—

Diseases of middle ear and mastoid

0.77

0.14

1.0

—

Varicose veins

1.19

0.14

1.0

—

Pneumonia (excl. viral and due to other infectious organisms not elsewhere classified)

113

0.87

0.14

1.1

1.0

—

1.16

0.11

1.0

—

Excessive attrition of teeth

1.13

0.10

1.0

—

Injuries to the abdomen, lower back, lumbar spine and pelvis

1.15

0.10

1.0

—

Organic, including symptomatic, mental disorders

1.09

0.09

1.0

—

Any mental disorder, or suicide (or attempt), or psychic disorders complicating pregnancy, partum or puerperium or nerve system disorders

1.11

0.09

1.0

—

Other viral diseases

1.11

0.09

1.0

—

Disorders of choroid and retina

1.13

0.09

1.0

—

Aplastic and other anaemias

1.08

0.09

1.0

—

Malignant neoplasm of breast, HER-positive

1.07

0.09

1.2

1.0

—

Hyperplasia of prostate

1.14

0.09

1.0

—

Other and unspecified disorders of vitreous body

1.11

0.09

1.0

—

Valvular heart disease excluding rheumatic fever

1.07

0.08

1.0

—

Non-rheumatic valve diseases

1.07

0.08

1.0

—

Injuries to the shoulder and upper arm

106

1.11

0.08

1.0

—

Disorders of vitreous body

1.09

0.08

1.0

—

Disorders of vitreous body and globe

1.07

0.08

1.0

—

Stroke, excluding SAH

0.81

0.07

1.0

—

Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium

0.85

0.07

1.0

—

Glaucoma

0.82

0.07

1.0

—

Malignant neoplasm of breast

1.09

0.07

1.1

1.0

—

Fracture of forearm

1.03

0.07

1.0

—

Fracture of lower leg, including ankle

1.02

0.07

1.0

—

1.11

0.05

1.0

—

Any event in cancer register

100

1.07

0.05

1.1

1.0

—

Malignant neoplasm, excluding all cancers (controls excluding all cancers)

1.06

0.03

1.1

1.0

—

Malignant neoplasm, wide definition for exclusion

1.06

0.03

1.1

1.0

—

Malignant neoplasm, wide definition for exclusion, excluding all cancers (controls excluding all cancers)

1.06

0.03

1.1

1.0

—

Substance abuse

1.09

0.03

1.0

—

Pneumonias (Asthma/COPD co-morbidities)

112

1.05

0.02

1.1

1.0

—

Mental and behavioural disorders due to psychoactive substance use

1.07

0.01

1.0

—

All pneumoniae

113

1.04

0.00

1.1

1.0

—

Pneumonia, organism unspecified

100

1.01

0.00

1.1

1.0

—

Other bacterial diseases

105

0.99

0.00

1.1

1.0

—

Use of hypnotics and sedatives

108

1.02

0.00

1.0

—

Cerebrovascular diseases

0.96

0.00

1.0

—

Failed induction of labour

0.00

0.0

1.0

—

Injury of nerves at wrist and hand level

0.00

0.0

1.0

—

Basal cell carcinoma, including avohilmo

0.87

0.00

1.0

—

Erectile dysfunction

0.00

0.0

1.0

—

Benign neoplasm of other and unspecified sites

0.00

0.0

1.0

—

Malignant neoplasm of bladder

0.00

0.0

1.0

—

Hyperfunction of pituitary gland

0.00

0.0

1.0

—

Giant cell arteritis

0.00

0.0

1.0

—

Benign neoplasm: Conjunctiva

0.00

0.0

1.0

—

Other/unspecified cytomegaloviral diseases

0.00

0.0

1.0

—

Other maltreatment syndromes

0.00

0.0

1.0

—

Other disorders of pigmentation

0.00

0.0

1.0

—

Congenital malformations of eye, ear, face and neck

0.00

0.0

1.0

—

Specific development disorders of speech and language

0.00

0.0

1.0

—

Dental pulpitis 3, only avohilmo

0.00

0.0

1.0

—

Brain meningioma, excluding all cancers (controls excluding all cancers)

0.00

0.0

1.0

—

Other eating disorders

0.00

0.0

1.0

—

Benign neoplasm: Conjunctiva

0.00

0.0

1.0

—

L01XX Other antineoplastic agents

0.00

0.0

1.1

—

Isolated proteinuria

0.00

0.0

1.0

—

Benign neoplasm of other and unspecified female genital organs

0.00

0.0

1.2

—

Injury of other and unspecified intrathoracic organs

0.00

0.0

1.0

—

Chronic conjunctivitis

0.00

0.0

1.0

—

Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified

0.00

0.0

1.1

—

Kidney transplant status

0.00

0.0

1.0

—

Congenital malformations of cardiac septa

0.00

0.0

1.0

—

≡ Risteys

FG R12 + FR

FinnGen R11 + FinRegistry

FinnGen R10 + FinRegistry

FinnGen R10

FinnGen R9

FinnGen R8

FinnGen R7

FinnGen R6

FinnGen R5

FinnGen R4

FinnGen R3

CNBP gene mutations found [Identifier] in Blood or Tissue by Molecular genetics method Nominal

Coding

Definition

OMOP mapping QC

Cohort

Year of birth distribution

Age at first measurement

Age at last measurement

Age at start of registry

Duration from first to last measurement

Statistics

Number of measurements over the years

Number of measurements per person

Distribution of lab values

Value range per person

LabWAS