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Acute appendicitis

K11_APPENDACUT

appendicitis: Acute inflammation of the vermiform appendix.

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 K35
Hospital discharge: ICD-9 540
Hospital discharge: ICD-8 540
Cause of death: ICD-10 K35
Cause of death: ICD-9 540
Cause of death: ICD-8 540

2 out of 7 registries used, show all original rules.

32585

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Check minimum number of events None

32585

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Include endpoints None

32585

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Remove individuals based on genotype QC

31628

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K11_APPENDACUT

Control definitions

Control exclude K11_APPENDIX

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 K35-K38
Name in latin Appendicitis acuta

Summary Statistics

Key figures

All Female Male
Number of individuals 31628 17142 14486
Unadjusted prevalence (%) 7.68 7.45 7.97
Mean age at first event (years) 34.63 32.64 36.99

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 1.29 [1.11, 1.49] 6.4e-4 2239
15 years 0.01 0.96 [0.84, 1.09] 5.4e-1 878
5 years 0.00 1.30 [1.12, 1.51] 5.4e-4 325
1 year 0.00 2.50 [2.01, 3.11] 1.6e-16 112

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: K11_APPENDACUT – Acute appendicitis
GWS hits: 22

Survival analyses between endpoints

Plot

before Acute appendicitis
after Acute appendicitis

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Acute appendicitis