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Acute appendicitis, no complications


appendicitis: Acute inflammation of the vermiform appendix.

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None


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Check conditions



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Check pre-conditions, main-only, mode, registry filters None

0 out of 7 registries used, show all original rules.


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Check minimum number of events None


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Include endpoints


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Remove individuals based on genotype QC


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Control definitions

Control exclude K11_APPENDIX
Control conditions not APPENDACUT_COMPLIC

Extra metadata

First used in FinnGen datafreeze DF3

Summary Statistics

Key figures

All Female Male
Number of individuals 24270 13631 10639
Unadjusted prevalence (%) 5.89 5.92 5.85
Mean age at first event (years) 34.12 32.28 36.47


Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.01 [0.80, 1.27] 9.3e-1 1376
15 years 0.01 0.77 [0.64, 0.93] 7.4e-3 518
5 years 0.00 1.14 [0.93, 1.38] 2.1e-1 194
1 year 0.00 1.99 [1.49, 2.67] 3.5e-6 60

Age distribution of first events

Year distribution of first events

Cumulative Incidence


Index endpoint: APPENDACUT_NOCOMPLIC – Acute appendicitis, no complications
GWS hits: 9

Survival analyses between endpoints


before Acute appendicitis, no complications
after Acute appendicitis, no complications

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Drugs most likely to be purchased after Acute appendicitis, no complications

Endpoint not on priority list, no data to show.