≡ Risteys
FG R12 + FR

Documentation Changelog GitHub Contact & Feedback

Silver Birch IgE Ab [Units/volume] in Serum

024681012141618202224↑ Number of records−20−100102030Measured value →
Number of people
1 431 (73.03% female)
People with ≥2 records
4.68%
Median duration from first to last measurement
1.36 years

Coding

Definition

OMOP Concept ID
3027300— open in OHDSI Athena.
Part of collection
Silver Birch (Betula verrucosa) IgE with 0 other OMOP concept — open in OHDSI Athena.

OMOP mapping QC

OMOP concept ID Test name Measurement unit (harmonized unit) N people N records Missing measurement value Harmonized value distribution
Test outcome
NA
N
A
AA
L
LL
H
HH
3027300 koivu — (—) 621 650 100.00% Distribution not available
3027300 igekoivu u/ml (—) 236 240 100.00% Distribution not available
3027300 koivu u/ml (u/ml) 197 204 0.00%
−19026
3027300 koivue u/ml (—) 166 179 100.00% Distribution not available
3027300 s-koivunsiitepöly,igevasta-aineet u/ml (—) 149 150 100.00% Distribution not available
3027300 s-allige,koivu/björk u/ml (—) 76 76 100.00% Distribution not available

Cohort

Number of people
1 431 (73.03% female)

Year of birth distribution

01020304050607080↑ Number of people1900192019401960198020002020Year of birth →

Age at first measurement

01020304050607080↑ Number of people020406080100Age at first measurement →

Age at last measurement

01020304050607080↑ Number of people020406080100Age at last measurement →

Age at start of registry

01020304050607080↑ Number of people020406080100Age at start of registry →

Duration from first to last measurement

012345678910↑ Number of people−6−4−20246810Duration →

Statistics

People with ≥2 records
4.68%
Median number of measurements per person
1.0
Median duration from first to last measurement
1.36 years

Number of measurements over the years

0510152025303540↑ Number of records201420162018202020222024Time →

Number of measurements per person

0.0k0.1k0.2k0.3k0.4k0.5k0.6k0.7k0.8k0.9k1.0k1.1k1.2k1.3k1.4k↑ Number of people020406080100120140160180200Number of measurements per person →

Distribution of lab values

024681012141618202224↑ Number of records−20−100102030Measured value →
Reference range
N people
N records
—
1042
1075
<0.35/kaikki
396
402
<0.35
21
22

Value range per person

No data available for the distribution of value range per person.

LabWAS

Endpoint
People with measurements
Mean N measurements
Mean measured value
Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
433
455
9.66
307.65
1.1
1.0
10.89
9.17
u/ml
0.24
95
42
363
316
11.79
307.65
1.1
1.0
11.68
7.54
u/ml
0.73
84
27
449
454
9.94
307.65
1.1
1.0
10.83
15.86
u/ml
0.53
98
28
423
348
6.72
201.40
1.1
1.0
9.66
10.92
u/ml
0.09
98
17
427
347
6.65
198.88
1.1
1.0
9.68
10.92
u/ml
0.09
99
17
390
347
6.83
197.77
1.1
1.0
9.46
10.92
u/ml
0.10
97
17
424
344
6.62
196.09
1.1
1.0
9.52
10.92
u/ml
0.10
98
17
389
344
6.78
194.92
1.1
1.0
9.55
10.92
u/ml
0.10
96
17
584
835
4.09
173.87
1.1
1.0
10.32
12.11
u/ml
0.32
111
82
204
228
8.90
162.25
1.1
1.0
11.53
5.04
u/ml
—
60
9
204
228
8.90
162.22
1.1
1.0
11.53
5.04
u/ml
—
60
9
157
145
10.91
144.80
1.1
1.0
11.60
5.15
u/ml
—
50
8
438
951
3.96
144.14
1.1
1.0
9.84
13.25
u/ml
0.71
107
79
157
150
10.55
141.46
1.1
1.0
11.60
5.15
u/ml
—
50
8
133
115
12.21
130.83
1.1
1.0
14.72
6.12
u/ml
—
38
9
545
866
3.42
124.71
1.1
1.0
9.60
13.03
u/ml
0.75
110
82
366
775
4.06
124.32
1.1
1.0
11.47
10.28
u/ml
0.19
70
89
405
989
3.69
122.33
1.1
1.0
9.82
12.60
u/ml
0.58
99
90
431
865
3.53
113.51
1.1
1.0
8.38
13.03
u/ml
1.14
91
82
471
922
3.36
112.86
1.1
1.0
11.03
9.84
u/ml
0.20
78
112
317
798
3.94
107.76
1.1
1.0
13.40
9.82
u/ml
0.64
56
94
321
849
3.75
101.94
1.0
1.0
13.48
9.66
u/ml
0.72
57
98
409
599
3.57
98.39
1.1
1.0
8.11
13.09
u/ml
0.89
62
48
371
979
3.32
95.05
1.1
1.0
12.73
10.33
u/ml
0.42
64
120
199
291
5.45
93.42
1.1
1.0
8.81
12.03
u/ml
0.20
43
14
199
288
5.45
93.15
1.1
1.0
8.81
12.03
u/ml
0.20
43
14
377
995
3.19
89.57
1.1
1.0
12.73
10.28
u/ml
0.44
64
121
226
522
4.24
84.62
1.1
1.0
12.47
8.80
u/ml
0.63
51
59
173
372
4.68
74.34
1.1
1.0
8.38
15.48
u/ml
0.76
32
30
242
664
3.60
72.86
1.1
1.0
11.61
12.33
u/ml
0.09
61
53
242
664
3.60
72.86
1.1
1.0
11.61
12.33
u/ml
0.09
61
53
270
356
3.81
69.80
1.0
1.0
9.21
10.92
u/ml
0.11
40
17
266
348
3.84
69.45
1.0
1.0
9.42
10.92
u/ml
0.10
39
17
266
348
3.84
69.45
1.0
1.0
9.42
10.92
u/ml
0.10
39
17
265
356
3.74
66.91
1.0
1.0
9.42
10.92
u/ml
0.10
39
17
209
559
3.73
66.40
1.1
1.0
11.45
11.73
u/ml
0.03
54
46
216
601
3.56
63.51
1.1
1.0
13.14
7.56
u/ml
1.19
47
64
72
79
9.21
59.52
1.1
1.0
11.38
6.58
u/ml
—
24
7
131
276
4.78
57.88
1.1
1.0
8.51
9.07
u/ml
0.06
32
21
391
879
2.52
54.70
1.1
1.0
9.25
12.51
u/ml
0.71
84
91
143
340
4.13
52.24
1.1
1.0
14.56
8.42
u/ml
0.98
40
38
90
153
5.96
50.59
1.1
1.0
8.82
4.84
u/ml
0.66
12
17
345
814
2.53
49.29
1.1
1.0
9.47
9.70
u/ml
0.03
53
92
356
885
2.44
47.67
1.1
1.0
7.98
11.85
u/ml
1.11
85
92
118
271
4.38
46.93
1.1
1.0
9.67
14.57
u/ml
0.40
20
19
197
279
3.55
46.59
1.0
1.0
5.36
6.08
u/ml
0.11
25
11
384
822
2.35
44.82
1.1
1.0
12.45
9.60
u/ml
0.53
61
93
254
585
2.76
43.79
1.1
1.0
10.55
13.35
u/ml
0.33
37
47
68
101
6.78
43.58
1.1
1.0
6.51
12.48
u/ml
—
11
10
384
935
2.26
42.36
1.1
1.0
9.41
12.72
u/ml
0.72
80
95
97
207
4.70
42.25
1.1
1.0
7.16
16.49
u/ml
0.77
16
18
101
170
4.76
41.04
1.0
1.0
13.54
5.66
u/ml
—
23
9
101
171
4.73
40.79
1.0
1.0
13.54
5.66
u/ml
—
23
9
375
914
2.24
40.63
1.1
1.0
9.99
12.08
u/ml
0.38
75
95
170
561
3.05
39.52
1.1
1.0
8.97
9.83
u/ml
0.11
29
68
113
294
3.88
38.17
1.1
1.0
12.27
6.37
u/ml
0.62
16
36
373
980
2.17
37.72
1.1
1.0
8.76
12.60
u/ml
0.98
82
103
151
485
3.14
36.83
1.1
1.0
8.66
7.96
u/ml
0.08
25
65
211
384
2.82
35.55
1.0
1.0
10.53
10.92
u/ml
0.04
29
46
138
410
3.24
35.38
1.1
1.0
14.41
10.00
u/ml
0.51
28
47
69
132
5.28
34.29
1.1
1.0
2.48
4.99
u/ml
1.02
14
17
318
711
2.25
33.90
1.0
1.0
11.50
9.63
u/ml
0.26
46
88
69
138
5.05
32.62
1.1
1.0
2.48
4.73
u/ml
0.92
14
18
194
677
2.55
31.46
1.1
1.1
6.75
11.20
u/ml
1.19
44
82
245
826
2.28
30.18
1.1
1.0
9.88
10.48
u/ml
0.09
42
107
127
298
3.20
29.87
1.1
1.0
11.23
11.09
u/ml
0.01
23
35
99
281
3.55
29.55
1.0
1.0
10.09
7.94
u/ml
0.22
19
36
133
460
2.91
28.63
1.1
1.0
12.28
8.92
u/ml
0.29
16
63
192
536
2.38
25.27
1.1
1.0
12.88
13.65
u/ml
0.06
26
63
24
20
12.58
24.01
1.1
1.0
7.52
4.58
u/ml
—
12
6
126
378
2.77
23.71
1.0
1.0
17.39
13.03
u/ml
0.33
22
34
60
117
4.44
23.42
1.1
1.1
8.17
9.24
u/ml
—
14
10
297
961
1.94
23.27
1.1
1.0
9.46
9.83
u/ml
0.05
46
123
292
747
1.96
22.34
1.0
1.0
10.20
10.43
u/ml
0.03
42
89
43
77
5.50
21.93
1.0
1.0
17.55
4.30
u/ml
—
8
6
84
264
3.19
21.38
1.1
1.0
8.40
9.21
u/ml
0.09
22
23
84
264
3.19
21.38
1.1
1.0
8.40
9.21
u/ml
0.09
22
23
36
59
6.15
21.09
1.1
1.1
2.32
3.99
u/ml
—
6
7
83
262
3.17
20.98
1.1
1.0
8.40
9.35
u/ml
0.10
22
22
311
884
1.86
20.74
1.1
1.0
9.96
9.66
u/ml
0.04
44
113
300
1072
1.84
20.30
1.1
1.0
11.83
10.90
u/ml
0.10
44
146
215
719
2.03
19.63
1.0
1.1
10.14
10.00
u/ml
0.02
43
94
147
382
2.34
18.52
1.1
1.0
6.39
11.15
u/ml
0.79
24
45
225
771
1.90
16.84
1.0
1.1
8.98
10.02
u/ml
0.16
43
100
227
910
1.87
16.84
1.1
1.0
12.46
10.02
u/ml
0.28
38
113
163
384
2.13
15.70
1.0
1.0
6.84
10.92
u/ml
0.63
17
46
289
831
1.74
15.61
1.1
1.0
10.46
9.80
u/ml
0.09
43
109
289
831
1.74
15.61
1.1
1.0
10.46
9.80
u/ml
0.09
43
109
135
629
2.15
15.59
1.1
1.0
9.84
8.06
u/ml
0.20
26
76
105
446
2.31
14.44
1.1
1.0
8.22
9.30
u/ml
0.15
14
57
232
646
1.80
14.05
1.1
1.0
8.68
12.93
u/ml
0.64
39
61
236
1090
1.71
13.22
1.1
1.0
11.40
10.97
u/ml
0.05
26
148
214
984
1.75
13.15
1.0
1.0
7.73
12.44
u/ml
1.16
34
130
145
710
1.95
12.89
1.1
1.0
8.04
11.30
u/ml
0.64
16
89
235
1092
1.69
12.72
1.1
1.0
11.40
10.90
u/ml
0.06
26
149
236
908
1.71
12.67
1.0
1.0
9.23
10.92
u/ml
0.29
45
112
208
942
1.74
12.52
1.0
1.0
7.89
12.46
u/ml
1.08
33
115
254
928
1.66
12.29
1.1
1.0
10.03
10.23
u/ml
0.03
57
111
231
1097
1.68
12.07
1.1
1.0
10.69
10.97
u/ml
0.03
28
148
49
128
3.16
11.93
1.1
1.1
6.64
13.22
u/ml
—
15
10
218
897
1.70
11.65
1.1
1.0
8.86
11.06
u/ml
0.33
28
117
277
1075
1.60
11.49
1.1
1.0
12.06
10.75
u/ml
0.19
55
131
251
1095
1.63
11.49
1.1
1.0
7.50
12.31
u/ml
1.48
41
145
250
1094
1.63
11.45
1.1
1.0
7.50
12.31
u/ml
1.48
41
145
153
781
1.83
11.19
1.1
1.0
10.78
9.19
u/ml
0.25
35
102
302
987
1.57
11.18
1.1
1.0
9.09
12.35
u/ml
0.64
46
120
226
912
1.65
10.72
1.1
1.0
7.66
11.76
u/ml
1.06
37
116
224
915
1.64
10.62
1.1
1.0
12.23
10.92
u/ml
0.13
31
123
309
1019
1.54
10.43
1.1
1.0
6.25
12.25
u/ml
2.82
41
145
44
119
3.08
10.32
1.1
1.1
6.63
13.22
u/ml
—
12
10
130
502
1.88
9.86
1.1
1.0
8.75
13.61
u/ml
0.64
24
60
200
610
1.65
9.02
1.1
1.0
4.84
12.16
u/ml
2.22
24
67
70
317
2.22
8.91
1.1
1.0
3.86
11.16
u/ml
—
7
47
181
907
1.64
8.86
1.1
1.0
6.84
12.00
u/ml
1.64
24
119
186
560
1.67
8.81
1.0
1.0
12.53
13.62
u/ml
0.09
24
64
230
1003
1.55
8.78
1.1
1.0
8.94
11.34
u/ml
0.28
29
140
63
275
2.30
8.75
1.0
1.0
27.08
6.11
u/ml
—
10
28
64
274
2.28
8.69
1.1
1.1
8.35
9.71
u/ml
0.08
15
33
203
787
1.60
8.69
1.1
1.0
10.60
10.81
u/ml
0.02
23
110
35
114
3.09
8.66
1.1
1.0
4.13
5.01
u/ml
—
8
13
171
569
1.68
8.66
1.0
1.0
10.92
13.08
u/ml
0.22
30
70
181
940
1.61
8.37
1.1
1.0
11.93
10.08
u/ml
0.14
18
124
74
351
2.11
8.34
1.1
1.0
8.33
7.02
u/ml
0.19
14
37
98
524
1.87
7.97
1.1
1.0
11.00
8.57
u/ml
0.23
21
65
74
356
2.06
7.93
1.1
1.0
11.36
8.35
u/ml
0.30
12
44
288
1022
1.46
7.92
1.1
1.0
7.48
10.17
u/ml
0.61
40
136
250
843
1.49
7.59
1.1
1.0
6.47
12.52
u/ml
1.75
34
101
229
939
1.51
7.57
1.1
1.0
6.17
11.36
u/ml
1.56
27
131
183
706
1.59
7.55
1.1
1.0
11.39
10.45
u/ml
0.10
32
82
66
148
2.25
7.50
1.0
1.0
6.93
17.08
u/ml
—
8
15
71
349
2.04
7.40
1.0
1.1
14.72
8.43
u/ml
0.50
14
44
182
573
1.60
7.38
1.1
1.0
8.24
11.48
u/ml
0.49
24
71
39
137
2.65
7.30
1.1
1.1
8.11
6.61
u/ml
—
8
15
77
393
1.96
7.24
1.1
1.0
7.81
8.43
u/ml
0.06
18
53
124
354
1.76
7.24
1.1
1.0
5.38
13.81
u/ml
1.85
15
36
241
1130
1.47
7.21
1.0
1.0
9.85
11.52
u/ml
0.25
47
144
150
827
1.61
7.08
1.0
1.0
8.62
12.17
u/ml
0.53
21
111
104
591
1.76
6.98
1.1
1.0
12.22
11.24
u/ml
0.08
14
67
23
66
3.50
6.98
1.0
1.0
3.56
20.39
u/ml
—
5
8
264
913
1.45
6.92
1.1
1.0
11.84
10.25
u/ml
0.19
36
122
130
698
1.65
6.83
1.1
1.0
7.32
11.54
u/ml
0.92
19
87
118
705
1.68
6.66
1.1
1.0
5.52
11.26
u/ml
1.71
23
90
153
825
1.58
6.65
1.1
1.0
7.51
12.28
u/ml
1.03
22
98
240
825
1.46
6.65
1.0
1.0
6.67
13.30
u/ml
2.05
27
107
255
943
1.44
6.62
1.0
1.0
12.46
10.71
u/ml
0.20
38
127
109
596
1.71
6.57
1.1
1.0
6.51
10.72
u/ml
0.85
15
73
247
1133
1.44
6.53
1.0
1.0
10.28
11.52
u/ml
0.18
47
144
247
1133
1.43
6.48
1.0
1.0
10.28
11.52
u/ml
0.18
47
144
70
171
2.06
6.47
1.1
1.0
5.23
8.22
u/ml
—
8
14
239
825
1.45
6.39
1.0
1.0
7.44
13.30
u/ml
1.57
26
107
116
592
1.67
6.31
1.0
1.0
19.79
9.20
u/ml
0.90
17
68
146
929
1.57
6.28
1.0
1.1
13.88
9.88
u/ml
0.42
22
124
220
918
1.46
6.28
1.1
1.0
10.00
11.65
u/ml
0.23
43
118
81
445
1.82
6.16
1.1
1.1
13.15
9.41
u/ml
0.31
16
60
79
433
1.83
6.04
1.0
1.0
9.68
10.19
u/ml
—
8
49
35
140
2.51
6.00
1.1
1.1
4.96
5.91
u/ml
—
10
16
170
869
1.51
5.97
1.1
1.0
8.84
10.94
u/ml
0.25
25
121
29
101
2.76
5.95
1.0
1.0
—
6.97
—
0
15
37
153
2.42
5.92
1.0
1.1
12.22
10.07
u/ml
—
5
17
186
1155
1.47
5.88
1.1
1.0
13.82
10.87
u/ml
0.28
25
155
156
1008
1.51
5.79
1.1
1.0
8.96
10.35
u/ml
0.17
30
134
254
962
1.39
5.55
1.0
1.0
11.15
11.32
u/ml
0.02
38
128
44
203
2.18
5.52
1.1
1.1
10.27
5.58
u/ml
—
10
34
24
83
2.90
5.45
1.0
1.1
11.65
4.21
u/ml
—
6
8
211
970
1.42
5.41
1.0
1.1
9.68
10.45
u/ml
0.12
27
134
147
968
1.51
5.37
1.1
1.0
5.85
11.18
u/ml
1.83
27
129
79
217
1.83
5.36
1.0
1.0
7.49
13.61
u/ml
—
8
23
79
217
1.83
5.36
1.0
1.0
7.49
13.61
u/ml
—
8
23
175
1131
1.45
5.30
1.1
1.0
12.14
10.93
u/ml
0.13
30
143
147
972
1.50
5.25
1.1
1.0
5.85
11.10
u/ml
1.79
27
130
259
979
1.38
5.24
1.0
1.0
5.77
11.69
u/ml
2.57
32
134
114
647
1.59
5.23
1.1
1.0
10.38
9.98
u/ml
0.04
21
89
262
977
1.37
5.16
1.0
1.0
9.52
11.24
u/ml
0.24
34
129
124
803
1.55
5.13
1.0
1.0
9.10
11.73
u/ml
0.36
17
100
26
98
2.66
5.07
1.0
1.0
5.88
6.24
u/ml
—
5
13
158
843
1.47
5.02
1.1
1.0
12.74
8.66
u/ml
0.60
29
109
60
325
1.85
4.87
1.1
1.1
8.60
6.18
u/ml
0.22
11
43
89
264
1.71
4.84
1.1
1.0
6.64
18.22
u/ml
1.60
12
32
171
786
1.44
4.78
1.1
1.0
8.77
9.92
u/ml
0.17
24
113
129
865
1.49
4.57
1.0
1.0
8.70
11.79
u/ml
0.41
21
108
39
172
2.11
4.53
1.0
1.0
21.57
15.34
u/ml
—
6
15
89
475
1.62
4.48
1.0
1.0
10.92
12.64
u/ml
0.14
12
51
37
175
2.12
4.42
1.1
1.0
3.49
9.50
u/ml
—
5
23
50
264
1.90
4.42
1.1
1.0
11.22
8.62
u/ml
0.18
12
26
80
989
0.62
4.40
1.0
1.1
18.61
9.18
u/ml
1.14
15
123
237
952
1.35
4.37
1.1
1.0
9.65
11.32
u/ml
0.24
37
128
162
756
1.43
4.36
1.1
1.1
5.99
10.98
u/ml
1.35
20
98
217
813
1.36
4.24
1.0
1.0
9.14
13.07
u/ml
0.45
22
104
59
333
1.77
4.24
1.0
1.0
11.97
8.71
u/ml
—
9
37
220
1188
1.34
4.17
1.1
1.0
15.25
10.06
u/ml
0.67
34
161
104
614
1.53
4.15
1.1
1.1
7.69
11.13
u/ml
0.56
13
87
50
270
1.86
4.15
1.1
1.0
9.40
7.33
u/ml
—
9
38
99
445
1.56
4.11
1.1
1.0
6.82
10.45
u/ml
0.57
11
59
63
188
1.79
4.11
1.2
1.0
5.92
14.21
u/ml
1.32
14
22
263
1001
1.32
4.10
1.1
1.0
11.79
10.05
u/ml
0.20
30
135
225
838
1.35
4.10
1.0
1.1
7.86
12.18
u/ml
1.06
29
94
225
838
1.35
4.10
1.0
1.1
7.86
12.18
u/ml
1.06
29
94
42
215
1.96
4.09
1.0
1.0
10.82
11.89
u/ml
—
5
26
232
882
1.34
4.07
1.1
1.0
9.50
12.26
u/ml
0.32
28
114
90
822
0.65
4.03
1.0
1.1
15.10
9.72
u/ml
—
8
120
86
507
1.58
4.00
1.1
1.0
18.43
10.54
u/ml
—
9
63
112
377
1.53
4.00
1.1
1.1
5.37
9.89
u/ml
1.05
16
54
44
193
1.93
3.99
1.1
1.0
6.63
7.80
u/ml
0.13
12
23
210
1218
1.34
3.96
1.1
1.0
5.97
11.81
u/ml
2.08
30
166
129
440
1.48
3.94
1.0
1.0
10.57
12.55
u/ml
0.14
17
61
48
259
1.85
3.93
1.1
1.0
18.11
8.02
u/ml
0.59
11
29
54
305
1.77
3.90
1.1
1.0
8.44
10.11
u/ml
0.12
11
39
91
822
0.65
3.89
1.0
1.1
15.10
9.72
u/ml
—
8
120
205
1194
1.34
3.85
1.0
1.0
7.82
11.51
u/ml
0.85
28
165
93
608
1.53
3.81
1.1
1.0
11.01
9.40
u/ml
0.14
16
69
62
367
1.69
3.81
1.0
1.0
9.95
9.69
u/ml
0.02
12
46
34
138
2.08
3.79
1.1
1.1
5.53
6.22
u/ml
—
10
19
57
331
1.72
3.76
1.1
1.0
9.40
8.74
u/ml
—
9
47
55
317
1.74
3.73
1.1
1.0
14.11
7.09
u/ml
—
9
51
54
255
1.76
3.73
1.1
1.1
6.14
11.26
u/ml
0.71
13
34
188
918
1.35
3.73
1.1
1.1
8.77
10.58
u/ml
0.29
24
128
140
738
1.42
3.72
1.0
1.0
7.37
12.19
u/ml
0.93
20
96
116
400
1.49
3.70
1.1
1.1
4.19
10.23
u/ml
1.97
15
58
46
253
1.82
3.65
1.1
1.0
3.28
9.20
u/ml
—
9
34
68
648
0.62
3.65
1.0
1.1
11.29
9.60
u/ml
0.18
11
87
43
194
1.88
3.65
1.1
1.0
6.63
7.80
u/ml
0.13
12
23
48
268
1.79
3.63
1.0
1.0
8.03
8.99
u/ml
—
9
32
71
443
1.61
3.58
1.1
1.1
3.40
14.39
u/ml
3.37
15
54
27
124
2.18
3.53
1.0
1.0
7.69
15.17
u/ml
—
8
13
177
895
1.35
3.51
1.1
1.1
9.76
10.23
u/ml
0.06
24
128
22
300
0.45
3.49
1.0
1.0
—
10.98
—
0
37
49
280
1.75
3.45
1.0
1.0
17.93
9.93
u/ml
—
9
33
64
397
1.62
3.34
1.0
1.1
20.43
7.40
u/ml
—
8
51
82
539
1.52
3.32
1.1
1.0
18.47
8.01
u/ml
0.81
14
65
223
903
1.30
3.30
1.1
1.0
7.61
12.44
u/ml
1.10
35
116
190
949
1.32
3.29
1.1
1.1
8.77
10.71
u/ml
0.31
24
132
49
285
1.72
3.26
1.0
1.1
6.10
10.88
u/ml
—
7
45
156
572
1.37
3.22
1.1
1.0
10.30
12.60
u/ml
0.17
17
67
91
791
0.68
3.22
1.0
1.1
17.07
9.75
u/ml
—
7
116
77
445
1.52
3.05
1.1
1.1
10.18
7.64
u/ml
0.26
14
68
163
624
1.34
3.00
1.0
1.0
8.51
10.75
u/ml
0.27
19
84
22
100
2.20
2.98
1.0
1.1
7.51
5.32
u/ml
—
6
11
236
929
1.27
2.97
1.1
1.0
11.99
11.56
u/ml
0.04
35
119
236
945
1.27
2.96
1.1
1.0
12.11
10.71
u/ml
0.14
32
127
32
579
0.55
2.93
1.1
1.0
4.90
9.35
u/ml
—
9
75
46
265
1.70
2.91
1.0
1.0
2.53
12.36
u/ml
—
5
29
45
265
1.70
2.90
1.1
1.0
7.15
8.87
u/ml
—
9
33
26
128
2.04
2.90
1.0
1.1
19.53
5.58
u/ml
—
6
15
107
524
1.41
2.90
1.1
1.0
6.68
11.17
u/ml
0.82
15
71
234
924
1.27
2.89
1.1
1.0
11.99
11.64
u/ml
0.03
35
118
64
410
1.55
2.88
1.0
1.1
3.04
10.51
u/ml
—
8
57
32
171
1.87
2.84
1.1
1.0
2.27
11.30
u/ml
—
6
24
111
909
0.72
2.84
1.0
1.1
15.64
10.01
u/ml
—
10
134
126
751
1.36
2.81
1.0
1.1
6.85
9.47
u/ml
0.29
11
101
48
291
1.65
2.80
1.0
1.0
5.60
9.27
u/ml
—
5
33
41
239
1.72
2.76
1.0
1.0
6.22
8.42
u/ml
—
8
31
42
247
1.70
2.74
1.0
1.0
6.22
8.87
u/ml
—
8
32
41
662
0.60
2.74
1.1
1.0
2.33
10.26
u/ml
—
8
86
52
325
1.60
2.70
1.1
1.0
4.41
12.13
u/ml
—
9
43
43
254
1.68
2.70
1.1
1.1
9.81
8.10
u/ml
—
7
36
157
947
1.31
2.69
1.1
1.0
8.37
10.00
u/ml
0.15
22
125
74
491
1.48
2.67
1.0
1.1
2.75
10.74
u/ml
—
9
66
10
32
3.14
2.64
1.0
1.1
—
4.59
—
0
6
174
687
1.30
2.64
1.0
1.1
8.17
10.38
u/ml
0.26
19
88
21
99
2.12
2.64
1.1
1.1
13.05
3.91
u/ml
—
7
11
21
99
2.12
2.64
1.1
1.1
13.05
3.91
u/ml
—
7
11
59
385
1.54
2.57
1.0
1.1
5.70
9.58
u/ml
—
7
59
138
782
1.32
2.55
1.1
1.0
8.38
9.17
u/ml
0.10
25
99
187
732
1.28
2.53
1.0
1.0
10.94
9.55
u/ml
0.13
23
94
216
898
1.26
2.52
1.1
1.0
10.32
12.44
u/ml
0.24
31
116
17
75
2.27
2.50
1.0
1.1
—
4.50
—
0
8
110
700
1.36
2.50
1.1
1.0
13.17
12.60
u/ml
0.04
11
85
56
751
0.66
2.50
1.0
1.1
14.31
8.94
u/ml
0.44
11
99
78
396
1.45
2.48
1.1
1.0
7.17
10.53
u/ml
0.61
13
50
39
202
1.69
2.47
1.1
1.0
9.69
6.50
u/ml
—
5
20
74
511
1.45
2.46
1.1
1.0
19.67
11.50
u/ml
0.45
11
63
56
755
0.66
2.46
1.1
1.0
7.66
10.30
u/ml
0.26
11
96
46
284
1.60
2.42
1.0
1.0
2.53
9.15
u/ml
—
5
39
154
864
1.29
2.38
1.0
1.0
4.99
10.37
u/ml
2.71
18
115
51
712
0.66
2.37
1.1
1.0
8.36
10.21
u/ml
—
10
92
34
198
1.72
2.34
1.1
1.0
4.65
12.35
u/ml
—
7
29
185
732
1.27
2.33
1.0
1.0
12.13
9.55
u/ml
0.23
20
94
49
314
1.56
2.33
1.1
1.0
11.77
9.12
u/ml
—
8
36
91
654
1.38
2.31
1.1
1.0
17.56
10.31
u/ml
0.48
14
86
100
652
1.36
2.31
1.1
1.0
11.32
9.72
u/ml
0.12
17
78
43
268
1.61
2.30
1.1
1.0
9.81
7.87
u/ml
—
7
33
31
177
1.75
2.29
1.1
1.0
6.44
9.34
u/ml
—
7
20
43
269
1.60
2.28
1.1
1.0
7.60
8.65
u/ml
—
5
33
26
120
1.85
2.22
1.2
1.1
6.89
5.77
u/ml
—
6
16
70
488
1.43
2.22
1.1
1.0
17.52
10.92
u/ml
—
10
62
25
136
1.84
2.17
1.1
1.0
27.83
4.78
u/ml
—
7
16
140
552
1.30
2.16
1.1
1.0
5.26
10.12
u/ml
1.26
16
75
140
552
1.30
2.16
1.1
1.0
5.26
10.12
u/ml
1.26
16
75
52
348
1.50
2.08
1.1
1.1
8.70
9.82
u/ml
—
6
47
24
131
1.83
2.07
1.0
1.1
7.51
8.07
u/ml
—
6
18
27
153
1.77
2.07
1.1
1.0
9.55
10.20
u/ml
—
6
20
27
153
1.77
2.07
1.1
1.1
8.27
4.83
u/ml
—
8
21
27
153
1.77
2.07
1.0
1.0
9.38
6.34
u/ml
—
6
15
50
477
0.67
2.06
1.0
1.0
7.62
10.71
u/ml
—
5
66
187
1079
1.23
2.04
1.1
1.0
7.11
10.65
u/ml
0.85
31
149
33
199
1.66
2.04
1.1
1.0
1.84
7.63
u/ml
—
5
28
46
465
0.66
2.04
1.0
1.0
3.30
10.96
u/ml
—
8
59
140
558
1.28
2.02
1.1
1.0
4.08
10.19
u/ml
2.13
15
77
18
90
2.00
2.00
1.2
1.0
4.17
4.92
u/ml
—
5
11
46
299
1.52
1.99
1.0
1.0
2.53
9.15
u/ml
—
5
39
36
132
1.64
1.97
1.1
1.0
6.16
9.74
u/ml
—
5
16
64
449
1.42
1.97
1.1
1.1
12.03
11.18
u/ml
—
10
63
46
683
0.67
1.97
1.0
1.0
4.54
9.99
u/ml
—
10
94
60
810
0.71
1.96
1.1
1.0
2.71
10.96
u/ml
—
9
110
200
1140
1.22
1.94
1.1
1.0
8.39
10.85
u/ml
0.35
28
161
95
607
1.33
1.93
1.1
1.0
9.33
8.65
u/ml
0.06
13
79
98
889
0.76
1.93
1.0
1.0
24.98
8.82
u/ml
1.11
13
120
127
808
1.28
1.91
1.0
1.0
6.46
10.02
u/ml
0.72
17
112
80
590
1.36
1.91
1.0
1.0
6.68
9.54
u/ml
0.31
12
82
63
828
0.72
1.90
1.1
1.0
2.75
11.07
u/ml
—
10
111
183
937
1.23
1.90
1.1
1.0
6.98
10.95
u/ml
1.13
24
130
141
683
1.26
1.89
1.1
1.1
8.33
10.61
u/ml
0.21
21
101
45
301
1.50
1.84
1.0
1.0
17.61
8.56
u/ml
—
7
32
163
827
1.24
1.81
1.1
1.0
7.44
9.80
u/ml
0.61
27
109
163
827
1.24
1.81
1.1
1.0
7.44
9.80
u/ml
0.61
27
109
44
293
1.50
1.81
1.1
1.0
32.00
9.28
u/ml
—
5
38
77
568
1.35
1.80
1.1
1.0
10.18
8.97
u/ml
0.11
14
80
9
35
2.58
1.80
1.0
1.0
—
3.13
—
0
7
52
360
1.45
1.80
1.1
1.1
8.66
8.53
u/ml
—
8
48
95
727
1.31
1.78
1.1
1.0
4.83
10.23
u/ml
—
9
98
208
973
1.20
1.76
1.1
1.0
6.73
11.42
u/ml
1.20
34
123
115
915
0.79
1.76
1.0
1.1
9.27
9.71
u/ml
0.04
19
117
83
625
1.33
1.75
1.0
1.1
6.68
10.17
u/ml
0.40
12
83
18
95
1.90
1.75
1.1
1.0
—
6.87
—
0
11
46
383
0.69
1.74
1.1
1.0
3.03
13.65
u/ml
—
6
45
84
634
1.33
1.74
1.1
1.0
5.43
10.29
u/ml
0.98
11
84
48
330
1.46
1.73
1.0
1.0
20.56
9.73
u/ml
—
5
42
38
249
1.53
1.72
1.1
1.0
7.20
9.39
u/ml
—
6
31
32
202
1.58
1.70
1.0
1.0
6.45
9.78
u/ml
—
8
28
0
49
0.00
1.68
0.0
1.0
—
4.59
—
0
7
63
541
0.73
1.66
1.0
1.0
8.97
10.48
u/ml
—
9
67
25
149
1.68
1.66
1.0
1.0
11.34
4.39
u/ml
—
5
18
135
1051
1.24
1.65
1.0
1.0
8.13
10.65
u/ml
0.58
22
142
141
1040
1.23
1.65
1.0
1.0
6.72
11.00
u/ml
1.03
20
136
85
616
1.31
1.63
1.1
1.1
6.88
10.06
u/ml
—
10
79
26
415
0.63
1.62
1.0
1.0
22.00
11.15
u/ml
—
6
43
227
1117
1.18
1.61
1.1
1.0
10.30
10.40
u/ml
0.01
36
150
7
26
2.70
1.58
1.1
1.0
—
3.61
—
0
5
32
484
0.66
1.57
1.1
1.0
2.15
12.01
u/ml
—
6
61
81
615
1.31
1.56
1.0
1.0
20.52
10.20
u/ml
—
10
76
105
821
0.79
1.54
1.1
1.0
7.06
10.84
u/ml
0.54
17
108
109
669
1.26
1.54
1.1
1.0
11.02
10.66
u/ml
0.02
14
91
124
508
1.25
1.53
1.1
1.0
4.80
10.67
u/ml
1.77
14
68
48
422
0.71
1.53
1.0
1.0
6.91
10.56
u/ml
—
5
60
150
627
1.22
1.53
1.0
1.0
3.46
9.82
u/ml
2.45
16
81
112
684
1.25
1.52
1.1
1.1
6.32
10.05
u/ml
0.84
15
90
65
473
1.34
1.51
1.0
1.0
9.92
12.81
u/ml
—
8
51
40
275
1.46
1.48
1.0
1.1
4.84
5.66
u/ml
—
6
44
148
622
1.22
1.44
1.0
1.0
4.61
9.75
u/ml
1.46
17
79
77
516
1.30
1.43
1.1
1.0
10.18
9.73
u/ml
0.04
14
70
47
337
1.40
1.41
1.1
1.0
5.10
9.71
u/ml
—
6
43
171
878
1.19
1.39
1.0
1.1
4.96
10.80
u/ml
2.74
27
112
43
431
0.71
1.39
1.1
1.0
9.36
10.82
u/ml
—
6
58
24
127
1.61
1.37
1.1
1.1
7.19
5.40
u/ml
—
7
16
192
888
1.18
1.36
1.0
1.1
9.00
11.26
u/ml
0.37
26
118
137
856
1.21
1.33
1.1
1.1
9.31
9.22
u/ml
0.01
19
123
114
929
1.22
1.33
1.0
1.0
8.49
10.03
u/ml
0.27
18
120
124
519
1.22
1.30
1.1
1.0
4.62
10.42
u/ml
1.71
13
71
39
275
1.42
1.30
1.0
1.1
11.10
10.07
u/ml
—
6
37
60
686
0.76
1.28
1.1
1.0
2.71
10.96
u/ml
—
9
78
73
677
0.78
1.27
1.1
1.1
13.16
9.99
u/ml
0.20
12
94
92
740
1.24
1.25
1.0
1.0
6.48
9.69
u/ml
0.77
15
95
92
740
1.24
1.25
1.0
1.0
6.48
9.69
u/ml
0.77
15
95
18
107
1.69
1.25
1.0
1.0
11.40
5.39
u/ml
—
5
13
52
591
0.75
1.25
1.1
1.0
11.66
10.55
u/ml
—
7
81
87
695
1.25
1.25
1.1
1.0
12.25
9.71
u/ml
0.24
12
86
5
118
0.42
1.24
1.2
1.1
—
5.24
—
0
17
171
744
1.18
1.24
1.1
1.0
5.57
12.07
u/ml
2.12
27
97
135
1067
1.19
1.23
1.0
1.0
11.20
10.16
u/ml
0.10
22
144
100
689
0.81
1.22
1.0
1.1
3.20
9.81
u/ml
4.25
13
103
54
365
1.33
1.22
1.1
1.0
7.21
7.50
u/ml
—
7
41
81
320
1.27
1.21
1.0
1.1
4.36
10.95
u/ml
—
8
37
42
348
0.73
1.21
1.0
1.0
3.96
11.54
u/ml
—
8
39
51
626
0.76
1.20
1.0
1.0
8.16
10.26
u/ml
—
10
84
165
847
1.18
1.20
1.0
1.1
5.35
10.63
u/ml
1.72
24
120
65
359
1.30
1.19
1.1
1.0
12.23
11.06
u/ml
—
8
46
230
1016
1.15
1.19
1.0
1.0
11.71
10.77
u/ml
0.11
25
143
26
341
0.68
1.18
1.1
1.0
4.19
9.38
u/ml
—
7
44
27
181
1.49
1.17
1.0
1.0
2.14
16.45
u/ml
—
7
14
21
133
1.58
1.17
1.1
1.0
5.17
10.30
u/ml
—
5
17
10
50
2.01
1.16
1.0
1.0
—
5.93
—
0
7
67
512
1.28
1.16
1.1
1.0
8.80
10.13
u/ml
0.14
14
70
0
33
0.00
1.16
0.0
1.0
—
4.12
—
0
5
0
33
0.00
1.16
0.0
1.1
—
4.77
—
0
5
0
35
0.00
1.15
0.0
1.0
—
5.93
—
0
7
65
603
0.78
1.15
1.0
1.1
15.21
9.68
u/ml
0.36
12
79
25
166
1.51
1.14
1.0
1.1
21.95
4.72
u/ml
—
5
21
35
249
1.41
1.14
1.1
1.1
8.70
5.86
u/ml
—
6
30
0
36
0.00
1.14
0.0
1.0
—
5.93
—
0
7
77
420
1.25
1.11
1.1
1.0
11.62
10.95
u/ml
0.03
12
59
84
388
1.25
1.11
1.1
1.0
6.54
12.01
u/ml
—
9
55
84
388
1.25
1.11
1.1
1.0
6.54
12.01
u/ml
—
9
55
52
397
1.31
1.10
1.0
1.0
16.64
10.51
u/ml
—
5
47
120
874
0.84
1.10
1.1
1.1
10.87
9.92
u/ml
0.08
19
121
40
251
1.37
1.09
1.1
1.0
9.41
9.05
u/ml
—
5
35
12
66
1.82
1.09
1.2
1.0
—
6.22
—
0
9
48
356
1.32
1.09
1.0
1.1
20.56
8.73
u/ml
—
5
50
28
193
1.45
1.09
1.0
1.0
5.80
7.74
u/ml
—
5
27
85
394
1.24
1.08
1.1
1.0
6.54
12.01
u/ml
—
9
55
30
422
0.71
1.08
1.1
1.0
22.12
9.38
u/ml
—
5
51
96
855
0.83
1.07
1.0
1.1
11.13
9.86
u/ml
0.18
19
115
37
238
1.38
1.07
1.1
1.0
11.48
9.68
u/ml
—
8
29
74
585
1.25
1.07
1.0
1.0
7.93
12.19
u/ml
0.61
13
76
96
855
0.83
1.06
1.0
1.1
11.13
9.86
u/ml
0.18
19
115
17
106
1.61
1.02
1.1
1.1
—
5.70
—
0
18
42
315
1.34
1.02
1.0
1.0
8.20
7.24
u/ml
—
5
44
52
614
0.78
1.01
1.1
1.1
11.66
10.67
u/ml
—
7
85
37
271
1.36
1.01
1.0
1.0
10.42
9.46
u/ml
—
6
32
5
109
0.46
1.00
1.0
1.0
—
6.32
—
0
14
148
636
1.17
0.99
1.1
1.0
6.24
9.07
u/ml
0.62
17
84
241
1072
1.13
0.98
1.0
1.0
9.09
10.57
u/ml
0.25
28
145
96
850
0.84
0.98
1.0
1.1
11.13
10.00
u/ml
0.15
19
112
5
23
2.18
0.98
1.0
1.0
—
3.59
—
0
6
128
782
1.17
0.98
1.1
1.0
7.98
10.39
u/ml
0.29
18
106
115
727
1.18
0.97
1.1
1.0
13.17
13.01
u/ml
0.01
11
87
0
30
0.00
0.97
0.0
1.0
—
4.22
—
0
5
119
854
0.85
0.97
1.1
1.1
10.87
9.06
u/ml
0.17
19
119
103
479
1.20
0.96
1.1
1.0
6.06
10.49
u/ml
0.59
18
60
138
1084
1.16
0.96
1.0
1.0
11.19
10.01
u/ml
0.11
22
148
66
434
0.80
0.95
1.1
1.0
2.55
12.79
u/ml
—
8
46
0
32
0.00
0.95
0.0
1.0
—
4.12
—
0
5
20
294
0.68
0.94
1.1
1.0
2.45
9.69
u/ml
—
5
31
16
85
1.60
0.94
1.2
1.1
8.14
5.24
u/ml
—
5
10
43
187
1.33
0.94
1.1
1.1
10.97
9.34
u/ml
—
7
25
6
118
0.51
0.93
1.0
1.1
—
3.64
—
0
16
96
778
1.19
0.93
1.1
1.0
14.71
12.03
u/ml
—
5
100
137
1082
1.16
0.93
1.0
1.0
11.20
10.08
u/ml
0.11
22
147
48
349
1.29
0.92
1.1
1.0
11.46
9.44
u/ml
—
10
44
161
988
0.87
0.92
1.0
1.1
11.43
10.80
u/ml
0.06
16
143
9
52
1.73
0.92
1.0
1.1
—
4.02
—
0
7
232
1056
1.12
0.92
1.0
1.0
11.40
10.76
u/ml
0.07
23
149
60
479
1.25
0.91
1.0
1.0
6.01
10.53
u/ml
—
8
62
40
299
1.32
0.91
1.0
1.0
6.74
11.04
u/ml
—
7
41
90
698
1.20
0.90
1.1
1.1
5.54
8.53
u/ml
—
5
106
59
473
1.25
0.90
1.1
1.1
6.42
9.57
u/ml
0.41
12
52
67
464
0.81
0.90
1.0
1.1
10.89
7.97
u/ml
0.22
14
73
5
102
0.49
0.89
1.2
1.1
—
4.93
—
0
15
28
167
1.39
0.89
1.1
1.0
8.41
7.99
u/ml
—
6
18
5
103
0.48
0.89
1.2
1.0
—
5.09
—
0
14
62
501
1.24
0.89
1.1
1.1
4.21
10.60
u/ml
2.03
12
68
79
403
1.21
0.87
1.0
1.0
5.03
10.65
u/ml
1.49
14
53
6
30
2.00
0.87
1.0
1.1
—
1.96
—
0
7
83
694
1.20
0.86
1.0
1.0
6.37
10.96
u/ml
1.14
17
89
37
281
1.32
0.86
1.1
1.0
14.80
11.19
u/ml
—
5
30
63
768
0.82
0.85
1.0
1.1
20.63
9.07
u/ml
—
7
103
6
31
1.94
0.84
1.2
1.0
—
4.06
—
0
7
90
827
0.85
0.84
1.0
1.1
11.30
10.18
u/ml
0.14
18
108
146
996
0.88
0.84
1.0
1.0
14.95
9.68
u/ml
0.52
23
139
42
323
1.29
0.84
1.0
1.0
4.37
15.38
u/ml
—
8
36
51
335
0.80
0.83
1.0
1.0
4.31
14.26
u/ml
—
7
36
208
1212
1.12
0.83
1.1
1.0
9.27
11.23
u/ml
0.29
22
172
92
619
1.18
0.82
1.1
1.1
9.95
10.29
u/ml
0.02
15
89
23
163
1.41
0.81
1.2
1.0
6.83
4.91
u/ml
—
5
19
12
73
1.65
0.81
1.2
1.0
18.63
5.44
u/ml
—
5
10
123
533
1.16
0.79
1.0
1.0
6.71
9.16
u/ml
0.51
14
70
58
418
1.23
0.79
1.0
1.0
13.83
8.90
u/ml
—
6
51
31
233
1.33
0.79
1.1
1.0
—
7.86
—
0
29
149
1008
0.88
0.79
1.0
1.0
14.95
9.63
u/ml
0.53
23
141
0
26
0.00
0.78
0.0
1.0
—
3.23
—
0
7
66
425
0.83
0.78
1.1
1.0
3.13
13.07
u/ml
—
8
45
0
27
0.00
0.77
0.0
1.0
—
4.06
—
0
7
26
191
1.36
0.76
1.1
1.0
13.67
5.59
u/ml
—
8
21
26
191
1.36
0.76
1.0
1.0
6.96
19.29
u/ml
—
6
18
144
991
0.88
0.76
1.0
1.0
11.86
9.95
u/ml
0.19
22
137
77
520
0.84
0.76
1.0
1.1
11.24
8.14
u/ml
0.26
15
74
10
59
1.70
0.75
1.0
1.1
—
2.81
—
0
7
54
456
0.82
0.75
1.1
1.0
9.98
10.40
u/ml
0.03
12
56
53
418
1.23
0.75
1.1
1.0
22.49
9.06
u/ml
—
9
57
5
24
2.09
0.74
1.0
1.0
—
3.59
—
0
6
108
705
0.87
0.74
1.0
1.1
12.19
9.04
u/ml
0.37
19
100
17
116
1.47
0.74
1.1
1.1
14.48
5.17
u/ml
—
6
13
70
322
1.20
0.74
1.1
1.0
8.24
9.16
u/ml
0.09
18
43
85
664
0.85
0.74
1.0
1.0
9.14
10.01
u/ml
0.08
11
86
37
285
1.28
0.73
1.0
1.0
18.86
8.29
u/ml
—
8
35
108
704
0.87
0.73
1.0
1.1
12.19
9.04
u/ml
0.37
19
100
131
762
1.14
0.71
1.0
1.0
8.11
8.09
u/ml
0.00
14
104
54
442
1.22
0.71
1.1
1.0
16.24
10.14
u/ml
—
9
55
31
238
1.30
0.70
1.1
1.1
2.24
6.98
u/ml
—
8
28
50
408
1.23
0.70
1.1
1.0
11.97
7.46
u/ml
—
6
51
148
1160
1.12
0.69
1.1
1.0
10.91
10.53
u/ml
0.04
21
161
32
294
0.78
0.69
1.1
1.1
6.63
7.40
u/ml
—
5
39
41
329
1.25
0.67
1.1
1.0
12.04
7.00
u/ml
—
5
46
35
266
1.27
0.67
1.0
1.0
8.31
7.96
u/ml
—
9
33
54
647
0.83
0.66
1.1
1.0
6.99
8.73
u/ml
—
10
89
93
566
1.16
0.66
1.1
1.0
8.93
13.80
u/ml
0.53
17
66
50
411
1.22
0.66
1.0
1.1
9.23
7.37
u/ml
—
5
58
5
95
0.53
0.66
1.0
1.1
—
4.57
—
0
11
123
985
1.13
0.65
1.1
1.0
11.73
11.42
u/ml
0.02
18
121
106
657
1.14
0.65
1.1
1.0
3.77
9.58
u/ml
2.31
16
98
27
206
1.31
0.65
1.1
1.0
26.20
9.52
u/ml
—
5
28
53
442
1.20
0.62
1.0
1.0
7.17
9.31
u/ml
—
8
56
10
63
1.59
0.62
1.1
1.0
—
5.21
—
0
11
61
257
1.19
0.61
1.0
1.0
6.32
11.94
u/ml
—
6
33
30
235
1.28
0.61
1.0
1.1
4.02
12.27
u/ml
—
5
35
60
378
0.84
0.61
1.1
1.0
2.70
14.26
u/ml
—
7
40
198
1188
1.10
0.60
1.1
1.0
9.12
11.28
u/ml
0.41
35
157
34
270
1.25
0.60
1.1
1.0
4.37
17.67
u/ml
—
8
28
44
362
1.22
0.59
1.0
1.0
10.79
8.51
u/ml
—
5
46
12
80
1.50
0.59
1.0
1.0
—
6.27
—
0
7
0
23
0.00
0.58
0.0
1.0
—
4.12
—
0
5
56
467
1.18
0.58
1.1
1.0
4.15
9.41
u/ml
—
8
62
33
264
1.25
0.57
1.0
1.0
1.54
5.91
u/ml
—
5
37
71
603
1.16
0.57
1.0
1.0
6.74
9.44
u/ml
0.38
11
80
25
193
1.30
0.57
1.1
1.1
12.50
5.75
u/ml
—
7
23
5
87
0.57
0.56
1.0
1.1
—
5.00
—
0
12
26
306
0.79
0.56
1.1
1.0
—
12.12
—
0
33
5
90
0.55
0.55
1.0
1.0
—
4.83
—
0
14
130
1122
1.11
0.55
1.0
1.0
10.64
11.68
u/ml
0.15
23
145
200
1216
0.92
0.55
1.1
1.0
11.84
10.85
u/ml
0.11
31
162
15
107
1.40
0.55
1.1
1.0
—
4.73
—
0
14
8
122
0.65
0.54
1.0
1.0
—
5.18
—
0
14
6
38
1.58
0.54
1.0
1.0
—
3.56
—
0
8
6
38
1.58
0.54
1.0
1.0
—
6.44
—
0
5
40
330
1.21
0.54
1.1
1.0
5.65
11.49
u/ml
—
7
45
62
716
0.86
0.54
1.0
1.1
8.57
10.84
u/ml
0.36
13
90
48
557
0.84
0.53
1.1
1.0
11.66
10.86
u/ml
—
7
76
174
987
1.09
0.53
1.1
1.0
8.39
10.45
u/ml
0.27
22
133
22
169
1.30
0.53
1.0
1.1
23.31
10.01
u/ml
—
5
20
39
319
1.21
0.53
1.1
1.0
6.42
9.89
u/ml
—
7
42
35
263
1.23
0.52
1.1
1.0
9.00
6.37
u/ml
—
6
22
31
250
1.24
0.52
1.0
1.1
15.13
4.77
u/ml
—
7
31
45
310
0.84
0.52
1.1
1.0
6.11
11.69
u/ml
—
7
36
55
470
1.17
0.52
1.1
1.0
18.94
10.23
u/ml
—
10
60
14
100
1.40
0.51
1.0
1.0
—
7.81
—
0
13
9
136
0.66
0.51
1.0
1.0
—
10.54
—
0
13
62
446
1.16
0.51
1.0
1.1
18.39
8.31
u/ml
—
10
57
43
480
0.84
0.50
1.0
1.0
8.20
8.81
u/ml
—
6
63
188
952
1.09
0.49
1.1
1.0
9.07
11.48
u/ml
0.24
22
133
48
491
0.85
0.49
1.1
1.0
5.52
8.61
u/ml
—
10
68
58
496
1.16
0.48
1.0
1.1
8.21
13.64
u/ml
—
7
55
16
212
0.75
0.48
1.3
1.0
12.81
6.72
u/ml
—
5
26
7
108
0.65
0.48
1.0
1.0
—
3.69
—
0
16
20
154
1.30
0.48
1.1
1.1
9.30
9.45
u/ml
—
8
19
40
314
1.19
0.48
1.1
1.0
15.31
11.33
u/ml
—
10
40
7
46
1.52
0.48
1.0
1.1
—
3.25
—
0
6
103
832
0.90
0.48
1.0
1.1
14.79
9.79
u/ml
0.65
22
105
132
754
1.10
0.48
1.1
1.0
6.66
11.17
u/ml
1.00
25
104
42
371
0.84
0.47
1.0
1.0
8.00
10.20
u/ml
—
7
46
170
1028
0.92
0.47
1.1
1.0
14.26
10.76
u/ml
0.41
21
149
105
975
0.90
0.47
1.1
1.0
12.62
10.49
u/ml
0.17
13
129
207
1064
1.08
0.46
1.1
1.0
9.81
10.43
u/ml
0.06
23
156
173
1040
0.92
0.46
1.1
1.0
14.26
10.76
u/ml
0.41
21
149
89
738
1.12
0.46
1.0
1.0
16.73
9.86
u/ml
0.48
15
92
7
49
1.43
0.46
1.0
1.0
—
3.59
—
0
6
5
83
0.60
0.45
1.0
1.0
—
3.50
—
0
11
8
119
0.67
0.45
1.0
1.1
—
4.47
—
0
15
131
852
0.91
0.45
1.0
1.1
12.31
8.41
u/ml
0.44
21
120
8
120
0.67
0.45
1.1
1.0
—
3.73
—
0
13
5
84
0.59
0.45
1.0
1.1
—
4.05
—
0
13
37
310
1.19
0.45
1.0
1.1
18.86
7.84
u/ml
—
8
47
147
926
0.92
0.45
1.0
1.0
12.15
9.53
u/ml
0.30
21
131
5
85
0.59
0.45
1.0
1.0
—
4.07
—
0
11
89
578
0.89
0.45
1.0
1.1
13.01
8.28
u/ml
0.56
17
84
14
103
1.36
0.45
1.1
1.1
—
4.83
—
0
15
59
451
0.87
0.45
1.1
1.0
6.16
9.33
u/ml
0.56
14
67
114
699
0.91
0.43
1.1
1.0
5.08
10.60
u/ml
1.62
20
96
77
392
1.13
0.43
1.0
1.0
1.29
11.70
u/ml
—
6
52
14
104
1.35
0.43
1.1
1.1
—
5.12
—
0
14
5
31
1.62
0.43
1.0
1.0
—
4.22
—
0
5
40
456
0.85
0.43
1.0
1.1
6.18
9.67
u/ml
—
5
63
8
56
1.43
0.42
1.0
1.0
—
12.64
—
0
6
12
87
1.38
0.42
1.0
1.1
—
5.74
—
0
10
112
512
1.10
0.41
1.0
1.0
4.89
12.06
u/ml
1.95
13
64
99
548
1.11
0.41
1.0
1.1
19.78
10.95
u/ml
—
8
81
34
386
0.84
0.41
1.0
1.0
19.85
8.21
u/ml
—
6
50
0
16
0.00
0.41
0.0
1.0
—
—
—
0
0
121
958
1.09
0.41
1.0
1.1
7.60
10.33
u/ml
0.50
13
134
37
265
0.85
0.40
1.1
1.0
1.78
10.99
u/ml
—
7
31
65
385
1.13
0.40
1.0
1.0
4.91
10.90
u/ml
—
10
51
89
435
1.11
0.40
1.0
1.1
8.46
13.16
u/ml
0.54
12
57
36
422
0.85
0.40
1.1
1.1
4.60
9.23
u/ml
—
6
55
36
422
0.85
0.40
1.1
1.1
4.60
9.13
u/ml
—
6
56
12
88
1.36
0.40
1.1
1.1
—
4.26
—
0
12
98
888
1.10
0.39
1.1
1.0
13.46
10.14
u/ml
0.27
17
112
5
35
1.43
0.39
1.0
1.0
—
4.22
—
0
5
42
442
0.87
0.38
1.0
1.0
41.84
8.98
u/ml
—
6
52
50
438
1.14
0.38
1.0
1.1
9.23
9.11
u/ml
—
5
62
8
113
0.71
0.37
1.0
1.1
—
3.80
—
0
17
5
37
1.35
0.37
1.2
1.1
—
3.17
—
0
6
9
70
1.29
0.36
1.0
1.0
—
3.66
—
0
10
10
130
0.74
0.36
1.1
1.0
—
11.02
—
0
13
145
975
1.08
0.36
1.1
1.0
8.51
11.38
u/ml
0.64
27
127
50
403
1.14
0.35
1.1
1.0
9.94
11.42
u/ml
—
9
45
68
405
1.12
0.35
1.1
1.0
8.14
10.05
u/ml
—
6
54
29
244
1.19
0.35
1.0
1.1
23.99
9.00
u/ml
—
7
33
108
670
0.92
0.35
1.0
1.1
11.61
8.78
u/ml
0.33
20
93
19
224
0.81
0.35
1.1
1.0
—
10.78
—
0
20
59
527
1.12
0.35
1.1
1.1
6.42
8.19
u/ml
0.21
12
68
6
44
1.36
0.34
1.0
1.0
—
4.16
—
0
6
74
544
0.91
0.34
1.1
1.0
13.23
7.66
u/ml
0.56
11
77
154
742
1.07
0.33
1.0
1.0
6.85
12.07
u/ml
1.21
18
97
123
899
0.93
0.33
1.0
1.1
14.95
9.53
u/ml
0.39
17
127
12
91
1.32
0.33
1.1
1.1
—
4.26
—
0
12
122
847
0.93
0.33
1.1
1.1
5.20
10.14
u/ml
1.66
21
115
36
312
1.15
0.33
1.0
1.1
12.30
7.20
u/ml
—
7
41
48
425
1.13
0.33
1.0
1.0
23.61
9.59
u/ml
—
8
55
96
535
1.09
0.33
1.1
1.1
15.80
10.54
u/ml
0.28
11
75
6
89
0.67
0.33
1.0
1.1
—
3.92
—
0
14
41
464
0.88
0.31
1.0
1.1
7.62
8.67
u/ml
—
5
74
127
648
1.08
0.31
1.0
1.1
11.21
10.05
u/ml
0.08
20
91
76
750
0.91
0.31
1.1
1.0
4.01
9.20
u/ml
—
9
113
7
53
1.32
0.31
1.1
1.0
—
4.99
—
0
8
10
131
0.76
0.30
1.1
1.1
—
6.44
—
0
17
15
120
1.25
0.30
1.0
1.0
—
10.47
—
0
18
119
713
1.07
0.29
1.1
1.0
4.58
11.27
u/ml
1.69
19
102
14
174
0.80
0.29
1.1
1.0
10.83
5.24
u/ml
—
5
20
7
56
1.25
0.29
1.0
1.1
—
3.49
—
0
6
41
363
1.13
0.29
1.0
1.0
23.15
8.25
u/ml
—
6
44
8
109
0.73
0.29
1.0
1.0
—
5.83
—
0
17
126
704
0.94
0.28
1.1
1.0
7.85
10.34
u/ml
0.37
24
97
40
288
0.89
0.28
1.1
1.0
4.87
11.05
u/ml
—
8
35
203
1013
1.05
0.27
1.1
1.0
5.66
12.46
u/ml
2.81
34
142
27
233
1.16
0.27
1.1
1.1
8.65
6.67
u/ml
—
6
39
32
279
1.14
0.27
1.1
1.1
10.28
9.59
u/ml
—
6
38
5
73
0.68
0.26
1.0
1.0
—
4.07
—
0
11
5
73
0.68
0.26
1.0
1.0
—
7.40
—
0
7
60
391
0.91
0.26
1.0
1.0
15.79
9.60
u/ml
0.58
13
48
123
788
0.94
0.25
1.0
1.1
12.17
9.13
u/ml
0.32
21
110
9
73
1.23
0.25
1.0
1.1
—
6.21
—
0
9
77
542
0.93
0.25
1.0
1.1
13.03
9.83
u/ml
0.23
14
71
32
361
0.89
0.24
1.1
1.1
5.90
7.53
u/ml
—
6
46
9
77
1.17
0.24
1.1
1.0
—
6.37
—
0
11
151
919
0.95
0.24
1.0
1.0
13.43
9.84
u/ml
0.45
20
129
6
81
0.74
0.24
1.0
1.0
—
7.89
—
0
11
63
430
1.09
0.24
1.0
1.0
15.98
11.56
u/ml
—
10
60
22
189
1.16
0.24
1.0
1.0
13.65
8.59
u/ml
—
6
31
49
446
1.10
0.23
1.1
1.0
18.51
8.40
u/ml
—
10
57
65
566
0.92
0.23
1.1
1.0
19.00
9.48
u/ml
—
7
82
197
1051
1.05
0.23
1.0
1.0
13.14
10.28
u/ml
0.36
26
145
26
296
0.88
0.23
1.1
1.1
6.81
6.58
u/ml
—
6
44
51
360
1.10
0.23
1.0
1.1
12.67
8.91
u/ml
—
6
46
12
97
1.24
0.22
1.0
1.0
12.90
7.70
u/ml
—
5
9
98
505
1.07
0.22
1.0
1.1
8.32
10.59
u/ml
—
9
75
5
40
1.25
0.22
1.0
1.0
—
4.92
—
0
5
7
95
0.74
0.22
1.0
1.1
—
4.47
—
0
13
98
875
1.06
0.22
1.1
1.1
6.37
10.31
u/ml
0.67
11
123
5
41
1.22
0.22
1.0
1.1
—
4.77
—
0
5
55
336
1.09
0.21
1.0
1.0
7.34
9.97
u/ml
—
8
47
5
42
1.19
0.21
1.0
1.0
—
6.75
—
0
6
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
16
135
1.19
0.21
1.1
1.1
—
7.51
—
0
19
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
31
345
0.90
0.21
1.0
1.0
11.78
11.30
u/ml
—
5
40
5
43
1.16
0.21
1.0
1.0
—
4.76
—
0
6
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
84
739
1.06
0.20
1.1
1.0
6.95
10.79
u/ml
0.43
14
89
25
209
1.13
0.20
1.1
1.0
5.22
10.37
u/ml
—
5
30
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
61
565
1.08
0.20
1.1
1.0
14.07
9.42
u/ml
—
7
71
6
48
1.25
0.20
1.0
1.0
—
3.22
—
0
6
19
211
0.87
0.20
1.2
1.1
12.90
7.44
u/ml
—
7
27
6
49
1.22
0.20
1.0
1.1
—
3.70
—
0
7
49
383
0.92
0.20
1.1
1.0
6.62
15.43
u/ml
—
5
42
15
176
0.85
0.19
1.0
1.0
10.63
3.59
u/ml
—
5
18
198
1075
0.96
0.19
1.1
1.0
9.93
11.05
u/ml
0.10
22
143
10
121
0.82
0.19
1.1
1.0
—
7.72
—
0
14
38
300
1.10
0.19
1.1
1.0
7.35
10.87
u/ml
—
6
42
6
52
1.15
0.19
1.0
1.0
—
6.53
—
0
7
6
52
1.15
0.19
1.0
1.1
—
5.76
—
0
10
198
1073
0.96
0.18
1.1
1.0
9.93
11.05
u/ml
0.10
22
143
28
251
1.12
0.18
1.1
1.1
5.17
9.20
u/ml
—
5
31
166
978
0.96
0.18
1.0
1.1
14.61
10.14
u/ml
0.57
23
141
21
238
0.88
0.18
1.0
1.1
10.86
7.46
u/ml
—
5
31
67
529
1.07
0.18
1.0
1.0
15.10
11.44
u/ml
—
6
61
24
213
1.13
0.18
1.1
1.0
15.18
5.42
u/ml
—
5
24
39
357
1.09
0.18
1.0
1.1
11.86
11.54
u/ml
—
9
47
12
100
1.20
0.18
1.0
1.1
—
3.33
—
0
12
7
60
1.17
0.18
1.1
1.0
—
6.64
—
0
8
73
440
1.06
0.18
1.1
1.0
4.58
10.54
u/ml
1.45
11
54
7
60
1.17
0.17
1.0
1.0
—
6.01
—
0
8
21
237
0.89
0.17
1.0
1.1
10.86
7.46
u/ml
—
5
31
61
571
1.07
0.17
1.0
1.0
6.92
9.54
u/ml
0.31
11
77
100
747
1.05
0.17
1.1
1.0
12.78
8.08
u/ml
0.74
18
104
50
432
0.93
0.17
1.0
1.1
9.81
8.68
u/ml
—
10
55
14
163
0.86
0.17
1.1
1.0
—
7.57
—
0
28
41
401
0.92
0.17
1.0
1.0
12.95
7.98
u/ml
—
5
47
30
262
1.10
0.17
1.1
1.0
5.90
8.06
u/ml
—
6
32
30
294
0.91
0.17
1.0
1.0
18.17
7.44
u/ml
—
6
34
5
67
0.75
0.17
1.2
1.0
—
3.34
—
0
9
5
61
0.71
0.17
1.0
1.0
—
7.10
—
0
7
5
68
0.73
0.17
1.2
1.0
—
3.57
—
0
10
5
70
0.71
0.16
1.0
1.0
—
7.89
—
0
11
41
256
1.09
0.16
1.0
1.1
7.35
10.72
u/ml
—
6
33
8
68
1.18
0.16
1.1
1.0
—
5.34
—
0
8
29
319
0.91
0.16
1.0
1.0
10.65
7.79
u/ml
—
6
41
8
70
1.14
0.16
1.1
1.0
—
5.78
—
0
11
14
120
1.17
0.16
1.1
1.1
—
7.40
—
0
17
217
1203
1.03
0.16
1.0
1.0
13.36
10.62
u/ml
0.33
33
160
14
162
0.86
0.16
1.0
1.1
18.18
8.51
u/ml
—
5
21
8
71
1.13
0.16
1.0
1.1
—
3.22
—
0
12
62
440
1.06
0.16
1.0
1.1
3.54
7.93
u/ml
—
5
58
55
583
0.94
0.16
1.1
1.0
11.76
8.82
u/ml
—
6
83
6
75
0.78
0.15
1.0
1.0
—
7.46
—
0
7
51
355
1.07
0.15
1.1
1.0
7.85
9.54
u/ml
—
8
46
6
78
0.77
0.15
1.0
1.1
—
5.06
—
0
8
13
86
1.17
0.15
1.1
1.1
12.80
9.77
u/ml
—
5
9
33
302
1.09
0.15
1.1
1.0
15.82
8.06
u/ml
—
6
36
170
1138
1.03
0.15
1.1
1.0
8.46
10.84
u/ml
0.55
28
150
9
64
1.11
0.15
1.0
1.1
—
4.17
—
0
7
37
249
1.08
0.15
1.0
1.0
15.59
11.98
u/ml
—
5
29
33
358
0.92
0.14
1.0
1.1
10.65
9.58
u/ml
—
6
48
7
88
0.79
0.14
1.0
1.1
—
4.90
—
0
12
112
1000
1.04
0.14
1.1
1.0
10.44
10.68
u/ml
0.02
16
124
16
141
1.14
0.13
1.0
1.1
24.60
8.68
u/ml
—
5
21
12
103
1.17
0.13
1.0
1.1
—
3.13
—
0
13
8
98
0.82
0.13
1.0
1.1
—
5.23
—
0
14
88
835
1.05
0.13
1.0
1.0
7.75
11.30
u/ml
—
10
101
49
461
1.06
0.13
1.0
1.0
8.13
8.28
u/ml
—
9
61
106
755
0.96
0.13
1.1
1.1
5.57
10.33
u/ml
1.31
19
104
23
252
0.91
0.12
1.0
1.1
10.42
7.36
u/ml
—
6
33
23
252
0.91
0.12
1.0
1.1
10.42
7.36
u/ml
—
6
33
77
425
1.05
0.12
1.0
1.0
5.43
9.88
u/ml
1.01
13
53
12
104
1.15
0.12
1.1
1.0
—
6.20
—
0
11
18
165
0.90
0.12
1.0
1.1
11.75
10.61
u/ml
—
6
19
29
259
1.08
0.12
1.1
1.0
6.82
8.06
u/ml
—
5
32
28
218
0.92
0.11
1.0
1.1
19.64
9.49
u/ml
—
5
29
171
1148
1.03
0.11
1.1
1.0
8.46
10.73
u/ml
0.51
28
152
79
758
1.04
0.11
1.1
1.0
9.46
10.23
u/ml
0.07
14
91
115
754
1.03
0.11
1.0
1.0
8.01
12.81
u/ml
0.49
14
92
12
105
1.14
0.11
1.0
1.1
—
3.26
—
0
15
12
105
1.14
0.11
1.0
1.0
—
5.05
—
0
13
52
494
1.05
0.11
1.1
1.0
7.08
8.87
u/ml
—
7
75
12
136
0.88
0.11
1.2
1.1
—
4.93
—
0
19
10
82
1.16
0.11
1.1
1.0
—
9.53
—
0
7
120
763
0.97
0.11
1.0
1.1
12.17
9.25
u/ml
0.30
21
102
86
487
1.04
0.10
1.0
1.1
1.23
11.02
u/ml
—
7
71
198
1053
0.98
0.10
1.1
1.0
9.11
11.22
u/ml
0.20
22
139
51
485
1.05
0.10
1.1
1.0
12.40
9.28
u/ml
—
6
63
198
1053
0.98
0.10
1.1
1.0
9.11
11.22
u/ml
0.20
22
139
86
521
1.04
0.10
1.0
1.1
1.16
10.68
u/ml
—
8
72
51
534
0.95
0.10
1.1
1.1
13.92
8.78
u/ml
—
5
81
11
94
1.15
0.10
1.0
1.0
—
5.35
—
0
12
198
1052
0.98
0.10
1.1
1.0
9.11
11.26
u/ml
0.21
22
138
88
660
1.04
0.10
1.0
1.1
18.14
8.75
u/ml
1.20
17
84
5
44
1.14
0.10
1.0
1.0
—
4.84
—
0
9
27
243
1.07
0.10
1.1
1.0
9.04
11.55
u/ml
—
5
29
5
45
1.11
0.09
1.2
1.0
—
5.14
—
0
8
5
46
1.09
0.09
1.0
1.0
—
6.70
—
0
7
5
46
1.09
0.09
1.0
1.1
—
3.47
—
0
8
56
404
0.96
0.09
1.1
1.0
8.88
8.90
u/ml
—
7
50
5
47
1.06
0.09
1.0
1.1
—
3.71
—
0
5
39
358
1.06
0.09
1.1
1.0
4.09
9.57
u/ml
—
9
39
126
773
0.97
0.09
1.0
1.1
12.44
9.17
u/ml
0.32
20
108
75
738
0.96
0.09
1.1
1.0
11.59
11.45
u/ml
0.01
11
83
41
376
1.05
0.09
1.0
1.1
2.80
13.53
u/ml
—
5
54
40
333
1.05
0.09
1.0
1.0
7.51
10.54
u/ml
—
6
49
25
233
1.07
0.09
1.0
1.0
22.78
6.81
u/ml
—
5
25
6
54
1.11
0.09
1.2
1.0
—
4.58
—
0
6
41
384
0.95
0.08
1.1
1.0
8.88
9.27
u/ml
—
10
54
27
208
0.94
0.08
1.0
1.1
19.64
10.22
u/ml
—
5
25
6
56
1.07
0.08
1.0
1.1
—
3.13
—
0
7
6
57
1.05
0.08
1.0
1.0
—
4.76
—
0
9
6
57
1.05
0.08
1.0
1.0
—
4.53
—
0
10
19
175
1.09
0.08
1.2
1.1
7.49
6.69
u/ml
—
5
29
126
771
0.97
0.08
1.0
1.1
12.44
8.48
u/ml
0.42
20
107
13
144
0.90
0.08
1.0
1.0
—
7.03
—
0
15
5
61
0.82
0.08
1.0
1.0
—
4.07
—
0
11
23
226
0.93
0.08
1.0
1.0
18.17
7.15
u/ml
—
6
28
5
65
0.77
0.08
1.0
1.0
—
3.10
—
0
11
5
65
0.77
0.08
1.0
1.1
—
5.06
—
0
8
44
416
1.05
0.08
1.0
1.0
17.06
8.31
u/ml
—
7
47
32
338
0.95
0.08
1.0
1.1
7.83
7.89
u/ml
—
5
42
7
67
1.04
0.08
1.0
1.0
—
4.39
—
0
10
17
182
0.92
0.07
1.1
1.0
18.65
6.48
u/ml
—
5
23
48
285
1.04
0.07
1.0
1.1
13.47
6.00
u/ml
—
6
37
6
70
0.85
0.07
1.0
1.0
—
7.09
—
0
7
6
71
0.84
0.07
1.0
1.1
—
8.24
—
0
9
37
257
1.05
0.07
1.0
1.0
15.59
11.98
u/ml
—
5
29
28
214
0.94
0.07
1.0
1.1
19.64
9.49
u/ml
—
5
29
8
74
1.08
0.07
1.1
1.1
—
3.09
—
0
12
73
753
0.97
0.07
1.1
1.1
19.70
9.09
u/ml
0.82
13
97
91
574
1.03
0.07
1.1
1.0
4.01
9.82
u/ml
1.85
14
79
8
78
1.03
0.07
1.0
1.0
—
4.07
—
0
11
25
235
1.06
0.07
1.0
1.0
16.82
4.57
u/ml
—
5
29
141
1032
0.98
0.07
1.1
1.0
8.77
10.58
u/ml
0.24
17
143
14
124
1.10
0.07
1.0
1.1
—
5.38
—
0
16
39
365
1.05
0.07
1.1
1.1
9.99
9.10
u/ml
—
7
47
46
442
1.04
0.07
1.0
1.0
10.14
10.80
u/ml
—
8
49
8
89
0.88
0.06
1.1
1.0
—
9.87
—
0
7
8
95
0.84
0.06
1.0
1.1
—
4.15
—
0
10
104
746
0.98
0.06
1.1
1.1
5.57
9.63
u/ml
1.11
19
101
123
682
0.98
0.06
1.1
1.0
8.27
9.16
u/ml
0.10
21
92
17
159
1.07
0.05
1.0
1.0
—
6.74
—
0
25
12
110
1.09
0.05
1.0
1.1
—
3.13
—
0
15
68
447
1.03
0.05
1.0
1.0
7.38
9.53
u/ml
—
9
60
84
727
1.02
0.05
1.1
1.1
5.73
9.52
u/ml
0.87
15
102
20
211
0.95
0.04
1.0
1.0
16.82
6.55
u/ml
—
5
26
95
616
1.02
0.04
1.1
1.1
8.53
8.77
u/ml
—
10
83
10
91
1.10
0.04
1.0
1.0
—
4.92
—
0
13
90
601
1.02
0.04
1.1
1.0
6.49
8.33
u/ml
0.30
16
87
39
378
1.03
0.04
1.1
1.1
14.04
10.00
u/ml
—
5
51
39
378
1.03
0.04
1.1
1.1
14.04
10.17
u/ml
—
5
50
80
512
0.98
0.03
1.1
1.0
5.88
10.36
u/ml
0.96
12
60
13
121
1.07
0.03
1.2
1.0
—
7.46
—
0
19
44
449
0.97
0.03
1.1
1.0
13.11
10.23
u/ml
—
6
56
13
139
0.94
0.03
1.1
1.1
—
4.67
—
0
18
131
785
0.99
0.03
1.0
1.1
12.44
9.27
u/ml
0.31
20
113
94
620
0.98
0.03
1.1
1.0
5.17
10.03
u/ml
1.41
12
96
61
568
1.02
0.03
1.1
1.1
4.38
10.63
u/ml
—
8
79
11
102
1.08
0.03
1.0
1.1
—
4.60
—
0
16
19
187
0.96
0.02
1.1
1.0
—
14.75
—
0
20
61
378
1.02
0.02
1.0
1.1
22.19
6.36
u/ml
1.13
12
45
36
351
1.03
0.02
1.1
1.0
14.80
10.30
u/ml
—
5
46
31
286
1.03
0.02
1.1
1.0
5.90
9.55
u/ml
—
6
36
14
132
1.06
0.02
1.1
1.1
—
7.86
—
0
18
76
705
0.99
0.02
1.0
1.1
8.89
9.81
u/ml
—
8
93
11
103
1.07
0.02
1.0
1.1
—
4.52
—
0
17
29
298
0.97
0.02
1.0
1.1
3.58
10.74
u/ml
—
5
35
11
100
1.06
0.01
1.0
1.0
—
5.35
—
0
12
99
653
1.01
0.01
1.1
1.1
11.26
10.69
u/ml
0.03
14
85
16
154
1.04
0.00
1.1
1.0
—
5.69
—
0
19
14
81
0.96
0.00
1.1
1.0
—
6.81
—
0
8
29
229
0.98
0.00
1.0
1.1
26.50
5.82
u/ml
—
8
28
77
742
1.00
0.00
1.0
1.0
3.21
11.69
u/ml
—
6
71
35
289
1.00
0.00
1.1
1.1
4.17
9.30
u/ml
—
5
36
15
143
0.97
0.00
1.0
1.0
—
7.86
—
0
23
54
511
1.01
0.00
1.1
1.0
8.18
8.55
u/ml
—
10
66
42
301
1.01
0.00
1.0
1.1
7.35
10.81
u/ml
—
6
41
165
901
1.00
0.00
1.0
1.0
8.34
12.46
u/ml
0.74
22
119
16
156
1.03
0.00
1.1
1.0
—
6.27
—
0
25
45
384
1.00
0.00
1.1
1.0
22.74
10.89
u/ml
—
5
56
34
336
1.01
0.00
1.0
1.1
21.65
6.67
u/ml
—
9
51
53
525
1.01
0.00
1.1
1.0
6.42
8.62
u/ml
—
5
81
22
225
0.98
0.00
1.1
1.0
—
7.65
—
0
26
39
379
1.00
0.00
1.1
1.1
9.99
9.10
u/ml
—
7
47
29
291
1.00
0.00
1.0
1.1
10.65
7.78
u/ml
—
6
36
42
312
0.99
0.00
1.0
1.1
7.54
13.89
u/ml
—
6
39
13
133
0.98
0.00
1.1
1.0
—
5.23
—
0
18
20
199
1.01
0.00
1.0
1.0
16.82
4.53
u/ml
—
5
26
178
1012
1.00
0.00
1.1
1.0
9.98
10.27
u/ml
0.03
18
144
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
6
59
0.91
0.00
1.0
1.1
—
5.40
—
0
7
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
6
66
0.91
0.00
1.0
1.1
—
9.98
—
0
9
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
22
220
1.00
0.00
1.0
1.1
—
8.68
—
0
35
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
17
170
1.00
0.00
1.1
1.0
—
6.13
—
0
21
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
9
89
1.01
0.00
1.1
1.1
—
5.87
—
0
12
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
7
69
1.01
0.00
1.0
1.0
—
3.95
—
0
11
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
8
81
0.99
0.00
1.0
1.1
—
3.59
—
0
10
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
6
67
0.90
0.00
1.0
1.0
—
3.84
—
0
9
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
8
73
0.99
0.00
1.0
1.1
—
7.15
—
0
7
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
6
59
1.02
0.00
1.0
1.1
—
3.60
—
0
8
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
6
69
0.86
0.00
1.0
1.0
—
6.77
—
0
6
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
5
54
0.92
0.00
1.0
1.0
—
6.81
—
0
9
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
6
64
0.94
0.00
1.0
1.0
—
4.63
—
0
7
5
52
0.96
0.00
1.0
1.0
—
6.25
—
0
10
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
6
59
1.02
0.00
1.0
1.1
—
5.23
—
0
8
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0