Haemangioma, any site

CD2_BENIGN_HEMANGIOMA

hemangioma: A benign vascular lesion characterized by the formation of capillary-sized or cavernous vascular channels.

Suggest a new description

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D18.0&
  • Hospital discharge: ICD-9 2280
  • Hospital discharge: ICD-8 22700
  • Cause of death: ICD-10 D18.0&
  • Cause of death: ICD-9 2280
  • Cause of death: ICD-8 22700

2 out of 7 registries used, show all original rules.

3313

4. Check minimum number of events

None

3313

5. Include endpoints

None

3313

6. Filter based on genotype QC (FinnGen only)

3313

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D18
Name in latin
Haemangioma (quovis loco)

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 28407 17050 11242
Only index persons 23788 14342 9446
Unadjusted period prevalence (%)
Whole population 0.42 0.49 0.31
Only index persons 0.46 0.53 0.36
Median age at first event (years)
Whole population 39.63 38.87 40.66
Only index persons 43.95 43.68 44.37

-FinnGen-

Key figures

All Female Male
Number of individuals 3313 2140 1173
Unadjusted period prevalence (%) 0.65 0.73 0.52
Median age at first event (years) 51.92 49.21 56.86

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
2960
Matched controls
29598
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D18.0
ICD-10 Finland
Haemangioma, any site
2653.3
323.0
2618
85
22700
ICD-8 Finland
Haemangioma and lymphangioma, Haemangioma
+∞
239.9
227
*
2280A
ICD-9 Finland
Haemangioma and lymphangioma, any site, Haemangioma, any site
+∞
205.6
195
*
EAA10
NOMESCO Finland
Excision of lesion of lip
10.3
54.3
109
109
ZXC12
NOMESCO Finland
Pulse colorlaser
23.1
48.5
70
31
Q27.3
ICD-10 Finland
Peripheral arteriovenous malformation
166.0
47.0
49
*
D18.1
ICD-10 Finland
Lymphangioma, any site
64.8
44.2
51
8
Q27.4
ICD-10 Finland
Congenital phlebectasia
155.7
43.9
46
*
QAA40
NOMESCO Finland
Laser therapy or photocoagulation of skin of head or neck
17.9
41.5
65
37
Q27.9
ICD-10 Finland
Congenital malformation of peripheral vascular system, unspecified
96.2
34.8
38
*
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
2.5
34.3
282
1180
D37.6
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Liver, gallbladder and bile ducts
7.2
33.4
82
116
Q82.50
ICD-10 Finland
Naevus flammeus
22.7
32.6
47
21
Q82.51
ICD-10 Finland
Naevus portwine
46.8
30.6
37
8
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
2.2
28.7
307
1463
XX6KT
NOMESCO Finland
Other sclerotherapy
151.4
28.7
30
*
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
4.1
27.3
109
273
QX3LT
NOMESCO Finland
Subcutaneous sclerotherapy
43.2
24.6
30
7
D18
ICD-10 Finland
Haemangioma and lymphangioma, any site
34.8
24.3
31
9
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.6
22.6
777
5451
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
2.3
22.4
215
970
QAA25
NOMESCO Finland
Destruction of lesion of head or neck
3.8
21.6
93
250
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.5
20.2
972
7325
Q82.58
ICD-10 Finland
Congenital non-neoplastic naevus
6.6
19.2
49
75
QCE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in upper limb
3.4
18.8
93
281
Q27.88
ICD-10 Finland
Other specified congenital malformation of peripheral vascular system
67.0
17.7
20
*
9736
FHL
Subcutaneous tumor removal in operating room or anesthesia
4.7
17.6
60
130
R23.8
ICD-10 Finland
Other and unspecified skin changes
1.7
17.5
406
2550
N02BE01
ATC
paracetamol; systemic, rectal
1.5
16.7
2374
21652
WZC10
NOMESCO Finland
Extensive specialist consultion with written report
2.4
16.4
146
637
Q28.3
ICD-10 Finland
Other malformations of cerebral vessels
9.8
16.1
32
33
D13.4
ICD-10 Finland
Benign neoplasm: Liver
7.9
16.0
36
46
QDE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in lower limb
2.8
15.9
102
370
R93.2
ICD-10 Finland
Abnormal findings on diagnostic imaging of liver and biliary tract
7.3
15.7
37
51
JN1DG
NOMESCO Finland
Very extensive MRI examination of upper part of abdomen with high intensity magnet
3.8
15.5
65
173
Z01.8
ICD-10 Finland
Other specified special examinations
1.5
15.2
563
3971
UJF32
NOMESCO Finland
Coloscopy
1.5
15.1
655
4774
S18
ICPC
Laceration/cut
1.4
15.1
1062
8486
AAB00
NOMESCO Finland
Extirpation of intracranial lesion
4.2
15.0
57
139
R07.4
ICD-10 Finland
Chest pain, unspecified
1.5
14.9
662
4851
SPAT1153
SPAT
Removal of sutures
1.4
14.7
815
6228
A02BC02
ATC
pantoprazole; systemic
1.4
14.6
1697
14711
ZXA00
NOMESCO Finland
Right side
1.5
14.5
675
4990
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.7
14.2
344
2177
9744
FHL
NA
+∞
13.5
13
*
WX408
NOMESCO Finland
General anesthesy, balanced
1.4
13.4
694
5224
D48.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Connective and other soft tissue
3.2
13.3
70
224
R22.0
ICD-10 Finland
Localized swelling, mass and lump, head
2.6
13.1
93
359
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
1.8
13.0
236
1373
J01DB01
ATC
cefalexin; oral
1.4
12.8
2238
20469
QAE99
NOMESCO Finland
Other excision or repair surgery of skin and subcutaneous tissue in head and neck
3.1
12.7
70
233
9733
FHL
Excision of skin change in operating room or anesthesia
4.0
12.3
48
121
EJA10
NOMESCO Finland
Biopsy of tongue or floor of mouth
3.2
12.3
64
204
EP1AE
NOMESCO Finland
Neck ultrasound examination
2.0
12.3
154
786
NDR20
NOMESCO Finland
Incomplete excision of soft tissue tumour of wrist or hand
3.7
12.1
52
143
A02BC03
ATC
lansoprazole; oral
1.4
12.0
718
5529
QBA40
NOMESCO Finland
Laser therapy or photocoagulation of skin of trunk
21.4
12.0
17
8
ZXC50
NOMESCO Finland
Cryotherapy
2.6
11.9
83
319
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
2.0
11.9
151
776
SAA03
NOMESCO Finland
Extended examination of mouth
1.3
11.8
1004
8188
ZQX00
NOMESCO Finland
0-4% of the skin
11.7
11.8
21
18
ZXC10
NOMESCO Finland
Use of laser
2.8
11.7
73
263
WX110
NOMESCO Finland
Local anesthesy
1.3
11.6
1842
16440
L82
ICD-10 Finland
Seborrhoeic keratosis
1.5
11.4
367
2495
A02BC01
ATC
omeprazole; systemic
1.4
11.2
681
5250
J01MA02
ATC
ciprofloxacin; systemic
1.3
11.2
936
7604
M25.5
ICD-10 Finland
Pain in joint
1.4
11.1
709
5514
WX002
NOMESCO Finland
Sedation and analgesia
1.5
11.0
473
3419
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
1.7
10.9
208
1229
ZXA05
NOMESCO Finland
Left side
1.4
10.7
604
4592
SAA02
NOMESCO Finland
Basic examination of mouth
1.3
10.7
1708
15160
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
1.3
10.7
798
6354
D22.9
ICD-10 Finland
Melanocytic naevi, unspecified
2.1
10.5
116
561
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.3
10.5
1004
8300
A02BC05
ATC
esomeprazole; systemic
1.3
10.4
998
8248
EP1LT
NOMESCO Finland
Percutaneous sclerotherapy of vascular malformation of head and neck
+∞
10.4
10
*
Q28.2
ICD-10 Finland
Arteriovenous malformation of cerebral vessels
8.8
10.3
21
24
N03AX12
ATC
gabapentin; oral
1.5
10.2
372
2596
TEA00
NOMESCO Finland
Biopsy of lip
4.3
10.2
36
84
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.6
10.1
293
1941
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.5
9.9
368
2579
N02AX02
ATC
tramadol; systemic, rectal
1.3
9.9
1030
8597
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.4
9.9
540
4078
D22.5
ICD-10 Finland
Melanocytic naevi of trunk
1.9
9.8
139
746
SAA01
NOMESCO Finland
Simple examination of mouth
1.3
9.8
1871
16913
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.3
9.8
1132
9586
QAA05
NOMESCO Finland
Incision for biopsy of skin of head or neck
2.7
9.8
66
251
QXA25
NOMESCO Finland
Destruction of lesion of skin, site unspecified
2.6
9.7
67
259
A06AC01
ATC
ispaghula (psylla seeds); oral
1.4
9.6
582
4474
PG1HT
NOMESCO Finland
Extensive endovascular embolisation of arterio-venous malformation not elsewhere classified
100.3
9.4
10
*
M01AH05
ATC
etoricoxib; oral
1.3
9.4
1510
13311
9734
FHL
Excision and local plastic or associated free skin grafting
5.3
9.3
27
51
EP1CG
NOMESCO Finland
Extensive MRI examination of soft tissue of neck with high intesity magnet
3.6
9.3
40
112
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.4
9.3
548
4192
EJB10
NOMESCO Finland
Excision of lesion of apex or body of tongue
6.4
9.2
23
36
QA4S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in face
6.0
9.2
24
40
JN3AD
NOMESCO Finland
Abdominal CT examination
1.7
9.2
174
1027
SPAT1263
SPAT
Sampling
1.3
9.1
1078
9124
B02AA02
ATC
tranexamic acid; systemic
1.5
9.1
373
2668
TPH04
NOMESCO Finland
Cathetrisation of vein
1.4
9.1
493
3713
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.3
9.0
1229
10595
E04.2
ICD-10 Finland
Nontoxic multinodular goitre
2.1
9.0
98
475
XX4BW
NOMESCO Finland
NA
7.4
8.9
20
27
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
1.9
8.9
127
684
N03AX16
ATC
pregabalin; oral
1.4
8.9
559
4320
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
2.2
8.8
90
425
9749
FHL
Other measure in this category
5.9
8.7
23
39
R01AD09
ATC
mometasone; nasal
1.3
8.6
1138
9750
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.4
8.6
386
2810
Q82.5
ICD-10 Finland
Congenital non-neoplastic naevus
9.0
8.5
17
19
M03BX02
ATC
tizanidine; oral
1.3
8.5
1595
14251
D23.3
ICD-10 Finland
Benign neoplasm: Skin of other and unspecified parts of face
2.3
8.5
72
312
S82
ICPC
Naevus/mole
1.5
8.4
280
1915
Q87.21
ICD-10 Finland
Klippel-Trénaunay-Weber syndrome
90.3
8.4
9
*
XQ845
NOMESCO Finland
Dermatoscopy
3.4
8.4
38
112
DM1CM
NOMESCO Finland
Paranasal sinuses extensive MRI examination with 3 Tesla magnet
+∞
8.3
8
*
QBA25
NOMESCO Finland
Destruction of lesion of skin of trunk
3.0
8.3
45
151
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.4
8.3
385
2821
D21.1
ICD-10 Finland
Benign neoplasm: Connective and other soft tissue of upper limb, including shoulder
3.7
8.2
34
93
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.3
8.2
1010
8571
J45.9
ICD-10 Finland
Asthma, unspecified
1.4
8.2
420
3129
XQ848
NOMESCO Finland
Dermatological photography
2.3
8.1
69
298
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.3
8.1
1033
8792
P01AB01
ATC
metronidazole; oral, rectal
1.3
8.1
991
8393
R06.0
ICD-10 Finland
Dyspnoea
1.3
8.1
553
4324
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
1.6
8.0
199
1272
M54.5
ICD-10 Finland
Low back pain
1.3
7.9
788
6497
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
1.9
7.9
105
551
R22.9
ICD-10 Finland
Localized swelling, mass and lump, unspecified
1.7
7.8
166
1017
UDQ12
NOMESCO Finland
Flexible laryngoscopy
1.8
7.8
133
762
K76.80
ICD-10 Finland
Hepatic cyst
4.1
7.8
28
68
NA2BG
NOMESCO Finland
Thoracal spine MRI examination with high intensity magnet
2.6
7.8
55
218
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
1.6
7.7
185
1170
KMAK
NOMESCO Finland
NA
1.2
7.6
1299
11425
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.3
7.6
823
6853
J01EA01
ATC
trimethoprim; systemic
1.3
7.6
592
4714
R22.1
ICD-10 Finland
Localized swelling, mass and lump, neck
2.0
7.6
90
453
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.4
7.5
389
2903
TQW99
NOMESCO Finland
Other minor procedure on skin
1.9
7.5
112
615
PG1GT
NOMESCO Finland
Endovascular embolisation of arterio-venous malformation with radiological guidance not elsewhere classified
80.3
7.4
8
*
N02AJ06
ATC
codeine and paracetamol; systemic
1.3
7.4
904
7643
SAA04
NOMESCO Finland
Special inverstigation of mouth
1.7
7.4
142
847
PG1JT
NOMESCO Finland
Very extensive endovascular embolisation of arterio-venous malformation not elsewhere classified
+∞
7.3
7
*
K14.9
ICD-10 Finland
Disease of tongue, unspecified
6.8
7.3
17
25
QAE40
NOMESCO Finland
Repair of anomaly or lesion after disease of skin of head or neck
9.4
7.3
14
15
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.4
7.2
442
3389
J01DA01
ATC
[U] cefalexin; systemic
1.2
7.2
1610
14549
Z31.5
ICD-10 Finland
Genetic counselling
1.8
7.2
124
715
4481A
ICD-9 Finland
Diseases of capillaries, Naevus, non-neoplastic
30.1
7.1
9
*
SBB00
NOMESCO Finland
Fotograf of mouth and teeth
1.9
7.1
103
559
D48.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Neoplasm of uncertain or unknown behaviour, unspecified
2.6
7.1
50
197
JN3BD
NOMESCO Finland
Extensive abdominal CT
1.5
7.1
248
1715
ZXA10
NOMESCO Finland
Bilateral
1.4
7.0
437
3363
QX3HE
NOMESCO Finland
Ultrsound examination of lesion close to skin
2.8
6.9
42
153
UJD02
NOMESCO Finland
Gastroscopy
1.8
6.9
109
610
R42
ICD-10 Finland
Dizziness and giddiness
1.3
6.9
485
3801
C05AA08
ATC
fluocortolone; rectal, topical
1.4
6.9
330
2429
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.2
6.8
1338
11900
R22.3
ICD-10 Finland
Localized swelling, mass and lump, upper limb
2.4
6.8
55
235
QAE30
NOMESCO Finland
Excision and repair of surgical scar in head or neck
10.9
6.8
12
11
CBB30
NOMESCO Finland
Excision of lesion of eyelid
2.2
6.8
66
308
XCW99
NOMESCO Finland
Other investigative procedure of eye
1.5
6.7
236
1637
PA5AC
NOMESCO Finland
Angiography of arteries to the face with X-ray
22.6
6.7
9
*
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
1.7
6.6
130
781
R51.80
ICD-10 Finland
Headache
1.4
6.6
354
2654
I78.8
ICD-10 Finland
Other diseases of capillaries
6.4
6.6
16
25
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.3
6.6
502
3981
Q28.8
ICD-10 Finland
Other specified congenital malformations of circulatory system
12.3
6.6
11
9
I86.8
ICD-10 Finland
Varicose veins of other specified sites
6.8
6.5
15
22
H04.10
ICD-10 Finland
Dry eye syndrome
1.5
6.4
229
1592
C07AB02
ATC
metoprolol; systemic
1.3
6.4
442
3452
EAW99
NOMESCO Finland
Other operation on lip
70.0
6.4
7
*
2281A
ICD-9 Finland
Haemangioma and lymphangioma, any site, Lymphangioma, any site
70.0
6.4
7
*
WX400
NOMESCO Finland
Inhalation anesthesy
1.8
6.4
105
597
SHA02
NOMESCO Finland
Correction of physiology of bite - basic therapy visit
1.6
6.4
157
999
I61.3
ICD-10 Finland
Intracerebral haemorrhage in brain stem
14.3
6.4
10
7
XXA00
NOMESCO Finland
Clinical examination requiring general anaesthesia
4.1
6.4
23
57
N03AX09
ATC
lamotrigine; oral
1.8
6.4
104
589
N05CF01
ATC
zopiclone; oral
1.3
6.4
720
6011
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
1.5
6.3
216
1486
E0000UV
ATC
NA
1.2
6.3
950
8195
QX3KT
NOMESCO Finland
NA
+∞
6.2
6
*
J01AA02
ATC
doxycycline; systemic
1.2
6.2
2033
18973
L57.0
ICD-10 Finland
Actinic keratosis
1.5
6.2
188
1265
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
1.5
6.0
185
1244
X59
ICD-10 Finland
Exposure to unspecified factor
1.3
6.0
417
3257
J02AC01
ATC
fluconazole; systemic
1.2
6.0
997
8675
SPAT1301
SPAT
No procedures
1.2
6.0
738
6213

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
1785
13986
1.60
37.34
6.3
6.3
10.9
11.5
umol/l
1.15
1698
13272
2450
20909
1.66
34.47
8.1
7.5
77.6
78.4
u/l
0.36
2337
19732
1143
8406
1.55
29.23
2.7
2.6
60.2
57.9
u/l
0.39
1064
7770
1443
11290
1.49
26.89
2.3
2.1
—
—
—
0
0
2343
20444
1.50
23.69
4.5
4.1
10.9
11.9
mm/h
3.38
2201
18992
1327
10426
1.45
23.07
8.3
8.9
1.2
1.2
inr
1.26
366
3071
1631
13343
1.44
22.68
7.0
6.9
1.2
1.2
mmol/l
0.12
1410
11310
1427
11520
1.42
20.67
5.3
4.9
35.9
35.7
g/l
0.55
1355
10736
186
920
2.08
18.74
2.5
3.5
79.5
4517.4
u/ml
0.85
157
782
1850
15801
1.39
18.36
4.7
4.8
6.5
6.6
mmol/l
2.82
1721
14747
1657
13908
1.38
18.23
6.2
5.9
0.6
0.6
e9/l
0.18
1454
12027
1143
9026
1.41
18.09
3.5
3.3
28.7
35.1
u/l
2.65
1083
8591
1709
14434
1.38
18.01
6.4
6.2
0.2
0.2
e9/l
0.02
1531
12696
1659
13957
1.38
17.84
6.2
6.0
0.0
0.0
e9/l
0.66
1454
12070
2416
21691
1.42
17.18
4.4
4.1
14.7
14.7
pmol/l
0.11
2219
19867
1689
14313
1.37
17.03
6.3
6.0
1.9
2.0
e9/l
0.17
1510
12640
2082
18285
1.37
16.49
3.5
3.1
47.2
46.4
u/l
0.14
1964
17132
2956
27698
1.62
16.39
16.0
13.7
21.8
22.9
mg/l
0.99
2394
21762
2990
28139
1.64
15.75
17.3
15.5
139.7
139.7
mmol/l
0.41
2926
27433
2758
25527
1.48
15.38
5.4
4.8
1.9
2.1
mu/l
0.80
2561
23561
2995
28230
1.63
15.28
17.4
15.6
3.9
4.0
mmol/l
2.63
2928
27481
1849
16092
1.34
14.64
9.1
9.0
3.9
4.0
e9/l
1.30
1645
14072
1517
12836
1.34
14.53
4.4
4.0
—
—
—
0
0
1435
12107
1.33
13.76
6.1
6.2
1.2
1.2
mmol/l
0.05
1317
11012
393
2670
1.54
13.16
3.5
4.0
27.1
19.3
ug/l
0.22
305
2146
2104
18812
1.32
13.01
4.9
4.3
—
—
—
0
0
3032
28840
1.60
12.77
15.1
12.7
—
—
—
0
0
1361
11491
1.31
12.63
2.4
2.3
77.8
77.1
nmol/l
0.44
1238
10405
180
1013
1.82
12.46
3.4
5.9
1.6
1.6
%
0.10
172
939
1478
12663
1.30
12.15
6.4
6.2
0.7
0.7
%
0.19
1388
11842
987
8011
1.33
11.96
3.4
3.2
143.7
85.3
e6/l
0.20
747
6148
439
3112
1.47
11.93
2.9
2.9
6.0
8.0
umol/l
2.42
380
2705
479
3458
1.45
11.83
2.5
2.3
132.1
129.6
ug/g
0.05
385
2741
1134
9403
1.31
11.77
6.0
6.0
—
—
—
0
0
599
4507
1.40
11.75
2.7
2.7
0.9
1.2
e6/l
1.25
347
2567
779
6121
1.36
11.69
1.9
1.8
1.3
1.2
mg/l
0.44
598
4624
863
6903
1.34
11.48
4.5
4.0
94.2
91.5
%
2.52
837
6728
965
7849
1.32
11.42
3.9
4.0
7.4
7.4
ph
0.53
165
1508
1141
9500
1.31
11.40
4.0
3.7
68.4
97.6
e6/l
1.04
816
6648
175
1006
1.78
11.31
3.5
6.0
0.9
0.9
%
0.13
168
935
808
6417
1.34
11.24
1.3
1.3
0.9
1.6
u/ml
3.51
193
1688
1507
13032
1.29
11.21
6.5
6.1
2.9
2.8
%
0.08
1416
12171
517
3821
1.42
11.20
1.2
1.2
—
—
—
0
0
2003
17962
1.29
11.17
4.9
4.4
790.2
2032.0
e6/l
0.98
24
241
651
5009
1.37
11.10
3.7
3.6
528.5
410.1
ng/l
0.25
451
3719
908
7366
1.32
10.84
3.2
3.1
0.3
0.4
e6/l
2.14
684
5555
1269
10770
1.29
10.80
2.0
2.0
95.0
96.3
pmol/l
0.42
648
5564
1549
13485
1.28
10.76
6.5
6.2
28.3
28.5
%
0.44
1454
12602
1223
10342
1.29
10.68
3.9
3.3
—
5.7
—
0
6
1509
13115
1.28
10.55
6.8
6.4
8.6
8.5
%
0.38
1425
12313
1527
13300
1.27
10.45
6.4
6.0
56.9
56.8
%
0.18
1434
12475
308
2103
1.51
10.02
2.6
2.8
10.6
10.4
g/l
0.25
286
1926
964
7956
1.30
10.00
2.1
2.1
140.2
207.9
u/l
3.64
902
7490
3052
29293
1.53
9.81
11.7
10.2
25.4
26.0
u/l
1.26
2965
28329
1526
13367
1.26
9.69
4.1
3.6
0.0
0.0
estimate
0.00
271
2496
205
1294
1.62
9.41
3.0
2.8
0.2
0.3
e6/l
1.39
199
1254
473
3543
1.39
9.39
1.4
1.3
—
—
—
0
0
705
5616
1.32
9.38
1.6
1.5
2.3
2.3
g/l
0.13
427
3439
3175
30797
1.74
9.35
23.9
20.1
254.5
255.2
e9/l
0.22
3109
30035
1541
13551
1.26
9.34
4.2
3.6
0.0
0.0
estimate
1.32
283
2472
3175
30810
1.73
9.16
23.8
20.0
90.7
90.8
fl
1.14
3140
30397
3175
30812
1.73
9.13
23.8
19.9
30.2
30.2
pg
1.59
3139
30396
3175
30815
1.73
9.08
23.9
20.0
4.5
4.5
e12/l
1.24
3096
29980
526
4031
1.36
9.05
2.3
2.3
29.9
29.7
s
0.18
508
3912
545
4200
1.36
9.04
3.1
2.9
3.7
2.8
e6/l
0.80
295
2275
3175
30819
1.72
9.02
23.9
20.1
6.7
6.7
e9/l
0.18
3097
29979
769
6231
1.30
9.00
4.7
4.5
—
—
—
0
0
3175
30826
1.72
8.92
24.0
20.2
135.1
134.9
g/l
0.25
3139
30409
505
3855
1.37
8.90
1.4
1.3
536.0
547.5
titre
0.05
100
829
1521
13412
1.25
8.80
5.7
4.8
0.0
0.0
estimate
0.42
290
2543
190
1210
1.60
8.44
3.5
3.3
25.6
25.3
mmol/l
0.60
185
1171
424
3185
1.38
8.23
1.9
1.7
—
—
—
0
0
866
7211
1.27
8.07
3.1
3.1
—
—
—
0
0
958
8091
1.26
7.89
3.3
3.0
—
—
—
0
0
353
2596
1.40
7.77
2.4
2.3
0.2
0.2
g/l
1.12
335
2437
242
1674
1.48
7.41
2.0
1.8
1.4
1.4
g/l
0.08
231
1531
265
1866
1.46
7.41
1.2
1.2
—
—
—
0
0
488
3806
1.33
7.39
2.6
2.5
2.4
2.3
g/l
0.94
453
3529
2523
23758
1.26
7.21
20.4
17.4
332.1
332.3
g/l
0.67
2509
23584
258
1821
1.45
7.13
3.3
3.3
4.5
4.5
pmol/l
0.24
233
1618
2055
18942
1.22
7.10
3.8
3.6
—
—
—
0
0
1007
8636
1.24
7.09
2.6
2.4
—
—
—
0
0
128
775
1.68
6.99
1.3
1.2
1074.3
1149.3
titre
—
7
27
706
5825
1.27
6.96
4.7
4.0
1.0
1.0
kg/l
0.21
101
838
1131
9837
1.23
6.93
3.7
3.5
107.5
102.6
ng/l
0.02
718
6410
1061
9173
1.23
6.88
3.3
3.4
2.4
2.4
mmol/l
0.11
931
8085
425
3283
1.34
6.86
6.3
7.0
104.6
104.4
mmol/l
0.53
419
3213
2469
23245
1.24
6.77
19.3
16.5
13.7
13.6
%
0.43
2439
22741
520
4145
1.30
6.71
2.6
2.5
13.1
13.4
umol/l
0.41
478
3852
842
7120
1.24
6.67
2.9
3.1
1155.7
1265.7
ng/l
0.34
710
6046
678
5594
1.27
6.65
2.6
2.6
4.6
6.1
e6/l
3.10
604
4890
266
1914
1.42
6.64
1.5
1.4
—
—
—
0
0
417
3234
1.33
6.55
1.5
1.4
—
—
—
0
0
451
3539
1.32
6.52
2.7
2.6
22.8
23.2
%
0.23
374
3047
633
5195
1.27
6.48
3.1
2.7
482.9
541.8
mosm/kgh2o
0.41
553
4420
2763
26401
1.28
6.39
4.7
4.4
5.9
5.9
mmol/l
0.44
2551
24189
105
618
1.72
6.39
5.4
4.2
—
—
—
0
0
391
3019
1.33
6.32
1.4
1.3
—
—
—
0
0
2799
26799
1.29
6.30
4.5
4.2
1.5
1.5
mmol/l
0.14
2610
24839
751
6306
1.25
6.29
4.2
3.5
—
—
—
0
0
124
770
1.63
6.18
1.3
1.2
106.0
91.6
titre
—
10
56
2708
25865
1.26
5.94
4.0
3.8
1.3
1.3
mmol/l
0.06
2503
23832
125
787
1.61
5.91
1.5
1.4
305.0
290.3
ug/g
0.38
77
440
95
557
1.73
5.89
3.9
8.5
10.7
11.1
mmol/l
0.94
88
493
95
558
1.72
5.86
3.9
8.5
105.5
105.3
mmol/l
0.24
88
494
196
1368
1.46
5.79
2.3
2.4
—
—
—
0
0
2851
27420
1.28
5.77
5.0
4.7
2.8
2.8
mmol/l
0.15
2663
25382
1371
12326
1.19
5.61
3.3
2.8
107.1
117.1
ug/l
0.99
1291
11461
2808
26988
1.27
5.49
4.6
4.3
4.7
4.7
mmol/l
0.16
2630
25153
303
2301
1.35
5.48
1.2
1.2
—
—
—
0
0
407
3227
1.30
5.44
24.6
23.6
1.4
1.3
inr
0.43
70
467
125
805
1.57
5.41
3.9
7.1
1.2
1.3
mmol/l
1.42
112
693
89
526
1.71
5.40
2.5
3.5
56.4
843.7
u/ml
0.97
80
489
280
2108
1.36
5.36
2.7
2.9
157.4
188.9
ng/l
0.71
251
1913
154
1047
1.49
5.22
2.5
2.5
20.7
21.5
s
1.78
133
924
2599
24806
1.22
5.20
5.9
5.5
39.2
39.5
mmol/mol
0.87
2439
23039
795
6850
1.21
5.07
2.8
2.2
3.0
2.9
mg/l
0.26
699
5862
1369
12389
1.18
5.02
10.2
9.3
0.0
0.0
e9/l
2.24
1125
10112
119
775
1.56
4.94
1.1
1.1
5.0
4.6
u/ml
0.03
12
103
226
1669
1.38
4.90
4.5
5.3
—
—
—
0
0
271
2067
1.34
4.79
3.6
3.7
4.9
4.7
kpa
0.51
264
2006
249
1881
1.35
4.69
1.3
1.3
141.7
203.2
u/ml
1.32
236
1735
562
4714
1.23
4.65
1.3
1.3
7.5
10.7
u/ml
0.56
220
1859
316
2479
1.30
4.58
3.8
4.2
5.8
5.8
kpa
0.03
308
2411
206
1516
1.38
4.58
1.4
1.4
30.3
29.7
iu/l
0.08
178
1295
150
1043
1.46
4.58
2.2
2.1
5687.8
4662.5
u/l
0.15
47
402
578
4874
1.23
4.54
2.9
3.0
2.4
2.4
mmol/l
0.39
505
4273
308
2413
1.30
4.51
6.4
8.6
121.3
121.8
g/l
0.18
300
2321
161
1138
1.44
4.51
1.3
1.2
—
—
—
0
0
332
2647
1.28
4.26
2.3
2.2
365.4
369.6
nmol/l
0.15
304
2431
357
2874
1.27
4.24
2.6
2.8
1.8
1.8
%
0.12
328
2556
229
1736
1.34
4.24
2.6
2.4
—
—
—
0
0
24
96
2.51
4.21
1.5
2.4
—
—
—
0
0
457
3792
1.24
4.17
2.0
2.0
—
—
—
0
0
311
2469
1.29
4.13
3.9
4.3
2.1
1.9
mmol/l
0.70
260
1979
796
6984
1.18
4.06
2.6
2.6
5881.9
4715.3
umol/l
0.31
705
6101
796
6985
1.18
4.05
4.5
4.3
—
—
—
0
0
279
2190
1.30
4.05
3.8
4.3
0.1
0.2
%
0.45
72
594
857
7568
1.18
4.04
4.1
3.7
—
—
—
0
0
326
2613
1.27
4.02
6.1
8.2
96.2
95.6
%
0.71
315
2520
361
2930
1.26
4.01
5.9
7.8
5.2
5.1
kpa
0.63
347
2795
361
2931
1.26
4.00
5.9
7.7
13.3
12.5
kpa
1.70
347
2796
360
2923
1.26
3.99
5.9
7.8
1.2
1.1
mmol/l
0.23
283
2274
264
2064
1.30
3.95
3.8
4.3
0.0
0.4
%
0.91
62
502
107
719
1.50
3.92
2.1
2.1
9.0
11.5
mg/l
2.58
99
661
153
1103
1.41
3.89
1.3
1.3
0.7
1.1
u/ml
—
10
93
209
1590
1.34
3.81
6.8
7.4
24.5
24.5
mmol/l
0.03
200
1477
694
6049
1.19
3.80
1.6
1.5
21.4
20.8
nmol/l
0.51
607
5182
576
4942
1.20
3.76
1.3
1.3
22.1
31.7
iu/ml
2.37
163
1565
755
6634
1.18
3.75
2.6
2.3
—
—
—
0
0
781
6884
1.18
3.74
5.2
4.8
2.2
2.8
ug/l
1.88
714
6168
289
2304
1.28
3.74
3.7
4.2
0.9
0.9
%
0.04
79
650
268
2118
1.29
3.71
2.7
2.7
66.8
66.5
g/l
0.26
239
1941
22
90
2.45
3.71
1.9
2.8
28.4
30.1
umol/l
0.26
14
62
551
4716
1.20
3.69
1.7
1.7
1153.7
1169.5
nmol/l
0.15
421
3587
183
1375
1.35
3.63
6.7
11.0
—
—
—
0
0
38
199
1.92
3.53
1.1
1.0
—
—
—
0
0
513
4392
1.20
3.42
3.5
3.7
0.8
0.8
mmol/l
0.49
467
4117
2639
25485
1.17
3.41
17.1
14.5
39.5
39.7
%
0.49
1932
18827
382
3182
1.23
3.38
1.4
1.6
—
—
—
0
0
127
918
1.40
3.23
2.4
2.4
10.3
10.3
g/l
0.02
106
787
48
279
1.73
3.23
4.9
4.5
15.2
85.6
u/ml
1.77
13
78
265
2137
1.26
3.15
2.4
2.7
69.6
70.2
e9/l
0.10
209
1621
298
2438
1.24
3.13
1.4
1.4
—
—
—
0
0
121
874
1.40
3.11
1.6
1.6
1.2
1.2
g/l
0.38
113
826
805
7207
1.15
3.09
4.6
4.0
0.0
0.0
estimate
1.49
280
2477
31
159
1.96
3.09
1.5
1.5
6.3
7.4
ug/l
0.37
31
137
63
399
1.59
3.07
1.0
1.1
1.9
2.8
u/ml
0.53
24
184
57
353
1.63
3.05
1.5
1.3
63.0
49.6
u/ml
—
6
21
173
1328
1.32
3.02
4.4
3.2
—
—
—
0
0
14
51
2.75
2.98
2.3
2.8
—
—
—
0
0
5
5
10.01
2.98
2.4
2.2
—
—
—
0
0
35
194
1.81
2.79
1.4
1.1
1.1
3.8
u/ml
0.97
13
79
481
4169
1.18
2.79
1.6
1.6
—
—
—
0
0
417
3574
1.19
2.76
5.4
6.2
1.0
1.1
mmol/l
2.40
389
3331
810
7308
1.14
2.76
1.7
1.6
1.3
1.4
mmol/l
0.85
705
6180
238
1934
1.25
2.69
2.5
2.4
14.5
23.0
au/ml
1.67
11
121
32
175
1.84
2.68
7.0
6.5
—
—
—
0
0
260
2142
1.23
2.60
2.2
2.4
4.6
6.8
ug/l
1.90
221
1901
308
2585
1.21
2.57
2.9
2.4
36.4
57.9
u/l
0.60
272
2217
266
2202
1.23
2.54
3.7
3.4
—
—
—
0
0
81
568
1.44
2.51
1.4
1.3
—
—
—
0
0
255
2106
1.23
2.50
3.5
4.0
0.5
0.6
%
0.50
55
463
632
5642
1.15
2.50
1.6
1.7
22476613.8
33242421.2
pmol/l
0.27
525
4744
43
265
1.63
2.41
2.5
2.1
—
—
—
0
0
802
7292
1.13
2.40
3.7
3.3
—
—
—
0
0
52
337
1.55
2.37
1.3
1.4
338.0
327.8
pmol/l
0.08
40
270
7
17
4.12
2.36
1.3
1.4
—
—
—
0
0
71
494
1.45
2.32
1.2
1.1
1.5
3.0
u/ml
0.93
15
128
112
845
1.34
2.28
1.6
1.6
0.2
0.2
g/l
1.18
104
798
83
597
1.40
2.27
1.2
1.1
1.4
1.8
u/ml
0.16
42
255
74
522
1.43
2.26
1.1
1.1
0.3
1.4
u/ml
2.37
34
241
135
1050
1.30
2.22
5.5
4.7
—
—
—
0
0
61
416
1.48
2.22
1.2
1.2
—
—
—
0
0
196
1596
1.24
2.22
1.3
1.2
—
—
—
0
0
5
9
5.56
2.21
1.2
4.4
4.1
4.4
mmol/l
—
5
9
137
1069
1.29
2.21
1.7
1.6
—
—
—
0
0
75
535
1.41
2.17
1.1
1.1
3.7
5.2
u/ml
0.50
39
286
36
219
1.65
2.15
1.1
1.2
—
—
—
0
0
249
2087
1.21
2.14
3.8
4.0
83.1
84.3
ng/l
0.08
217
1828
780
7131
1.12
2.11
6.5
6.8
—
—
—
0
0
21
109
1.93
2.10
1.1
1.1
2.4
8.9
u/ml
0.43
11
63
213
1764
1.22
2.08
1.3
1.3
28.5
46.6
au/ml
—
7
79
118
912
1.30
2.06
2.7
2.5
—
—
—
0
0
32
191
1.68
2.06
1.0
1.1
—
—
—
0
0
41
261
1.58
2.06
1.1
1.1
—
—
—
0
0
31
184
1.69
2.04
1.3
1.2
—
—
—
0
0
102
775
1.33
2.02
5.7
5.5
1.4
1.5
mg/l
0.14
96
718
18
90
2.01
2.00
2.1
1.6
13.8
14.6
pmol/l
0.26
18
78
257
2180
1.19
1.97
3.7
3.8
1.2
1.2
mmol/l
0.79
234
1900
72
520
1.39
1.97
2.0
1.6
—
—
—
0
0
143
1142
1.26
1.95
1.5
1.9
1.5
1.5
g/l
0.28
129
993
148
1187
1.26
1.95
2.6
3.0
0.7
0.7
%
0.33
142
1140
5
11
4.55
1.94
3.0
1.0
—
—
—
0
0
71
514
1.39
1.92
1.5
1.3
—
—
—
0
0
199
1653
1.22
1.91
2.5
2.2
11.9
12.4
nmol/l
0.44
182
1455
159
1292
1.24
1.88
5.0
4.7
—
—
—
0
0
100
767
1.31
1.87
1.4
1.4
9.2
11.1
u/l
0.78
81
622
62
443
1.41
1.82
1.3
1.6
—
—
—
0
0
31
191
1.63
1.80
1.4
1.1
27.3
2.2
u/ml
—
10
62
44
295
1.50
1.79
2.8
2.5
—
—
—
0
0
127
1012
1.27
1.79
2.1
2.0
0.9
2.4
ug/l
1.98
111
903
51
354
1.45
1.76
1.4
1.3
—
—
nmol/l
—
0
0
19
102
1.87
1.76
1.3
1.0
—
—
—
0
0
149
1213
1.24
1.75
2.6
3.0
1.4
1.2
%
1.00
149
1205
12
54
2.23
1.73
2.8
3.0
—
—
—
0
0
42
282
1.50
1.71
1.6
1.3
7.1
6.6
g/l
0.58
29
195
48
332
1.45
1.70
2.0
2.5
8.3
7.6
umol/l
0.08
37
240
80
605
1.33
1.68
2.2
2.4
95.8
113.1
ug/min
0.14
39
372
39
259
1.51
1.68
1.4
1.2
—
—
—
0
0
42
284
1.48
1.66
1.6
1.4
—
—
—
0
0
61
443
1.38
1.66
2.0
1.6
0.6
0.8
g/l
0.93
44
333
11
49
2.25
1.63
1.1
1.5
—
—
—
0
0
35
230
1.53
1.59
3.5
2.8
89.5
29.9
mg/l
0.42
27
166
14
70
2.00
1.59
1.9
2.5
—
—
—
0
0
117
940
1.25
1.57
3.2
3.6
0.4
0.3
g/l
0.40
55
401
239
2060
1.17
1.57
1.1
1.2
100.0
154.6
iu/ml
2.19
98
786
41
281
1.46
1.54
1.6
1.3
2.9
2.9
g/l
0.02
29
195
41
281
1.46
1.54
1.6
1.3
0.4
0.4
g/l
0.22
29
193
29
184
1.58
1.54
1.8
1.4
2343.3
1933.6
ml
1.02
11
31
302
2658
1.15
1.51
1.6
1.4
—
—
—
0
0
73
556
1.32
1.49
3.5
3.6
58.7
57.1
%
0.51
73
556
96
762
1.27
1.45
3.8
3.4
4.1
1.6
ratio
—
9
62
58
429
1.36
1.45
1.3
1.2
11.1
4.8
u/ml
0.98
19
187
203
1740
1.18
1.44
4.8
4.6
7.4
7.4
ph
0.04
17
204
37
253
1.47
1.42
1.3
1.6
—
—
—
0
0
56
414
1.36
1.41
1.1
1.1
4.4
5.3
u/ml
0.15
20
166
549
5036
1.11
1.41
1.7
1.8
—
—
—
0
0
40
279
1.44
1.40
1.8
2.4
1.4
1.2
e9/l
0.15
27
167
98
784
1.26
1.40
3.9
3.5
24.7
73.0
mg/l
1.96
73
640
114
928
1.24
1.40
1.4
1.3
—
—
—
0
0
91
722
1.27
1.39
1.1
1.1
—
—
—
0
0
93
744
1.26
1.34
1.4
1.2
28.3
3.4
u/ml
0.46
12
84
11
54
2.04
1.32
1.5
2.3
16.7
18.5
umol/l
0.18
11
54
845
7934
1.09
1.32
4.1
4.0
28.3
8.8
mg/mmol
0.46
539
4973
97
782
1.25
1.31
3.9
3.5
49.2
62.6
mg/l
0.45
72
638
0
41
0.00
1.31
0.0
5.5
—
—
—
0
0
62
472
1.32
1.31
1.5
1.6
—
—
—
0
0
203
1757
1.17
1.30
4.9
4.5
5.1
5.2
kpa
0.21
187
1639
27
403
0.67
1.30
1.8
1.8
—
4.0
—
0
7
804
7539
1.09
1.29
3.3
3.3
790.8
332.5
mg/l
1.16
514
4724
29
193
1.51
1.29
1.7
1.8
6.7
6.7
mmol/l
0.02
22
127
80
632
1.27
1.29
1.4
1.7
1821.3
1214.6
e6/l
0.17
64
515
16
91
1.76
1.28
1.3
1.1
—
—
—
0
0
299
2664
1.13
1.28
4.9
4.2
—
—
—
0
0
66
509
1.30
1.27
2.7
3.2
—
—
—
0
0
8
35
2.29
1.26
1.3
1.1
—
—
—
0
0
136
1141
1.20
1.26
5.2
4.9
24.9
24.7
mmol/l
0.25
130
1075
54
406
1.34
1.25
1.2
1.2
—
—
—
0
0
58
441
1.32
1.24
1.2
1.4
28.3
28.3
u/l
0.00
47
364
74
583
1.28
1.23
2.0
2.3
134.7
130.1
g/l
0.69
52
436
25
163
1.54
1.23
1.2
1.1
1.1
3.5
u/ml
—
5
24
60
460
1.31
1.22
1.4
1.5
0.2
0.3
nmol/l
1.92
43
353
14
78
1.80
1.21
1.1
1.3
—
—
—
0
0
26
172
1.52
1.20
1.1
1.1
1.1
1.0
ratio
—
5
69
75
594
1.27
1.20
4.1
3.5
—
—
—
0
0
23
148
1.56
1.20
1.3
1.3
161.8
312.5
u/l
1.26
23
134
8
38
2.11
1.18
1.1
1.0
—
—
—
0
0
120
1003
1.20
1.18
1.8
1.6
291.6
304.2
mu/l
0.20
110
905
79
632
1.26
1.17
1.4
1.6
8.5
27.6
e6/l
1.18
61
486
50
376
1.33
1.17
1.1
1.1
8.5
4.7
u/ml
0.40
21
165
29
198
1.47
1.16
1.1
1.1
7.1
9.8
iu/ml
—
6
50
258
2294
1.14
1.16
6.2
7.3
1.3
1.3
mmol/l
0.72
251
2213
24
158
1.52
1.14
1.3
1.2
—
—
—
0
0
49
369
1.33
1.14
1.4
1.3
—
—
—
0
0
27
183
1.48
1.13
1.0
1.0
—
—
—
0
0
335
3039
1.11
1.09
1.7
1.7
—
—
—
0
0
8
41
1.95
1.08
1.1
1.1
—
—
—
0
0
19
120
1.59
1.08
1.3
1.4
32.6
31.8
nmol/l
0.03
14
100
59
461
1.28
1.07
1.3
1.2
—
—
—
0
0
43
321
1.34
1.07
1.5
1.4
2.9
4.1
ug/l
0.64
33
282
265
2375
1.13
1.07
7.0
8.2
8.3
9.3
mmol/l
1.92
257
2276
57
444
1.29
1.06
1.3
1.2
—
—
—
0
0
78
633
1.24
1.04
1.2
1.5
3.9
3.7
mmol/l
0.42
71
599
251
2252
1.12
1.01
6.8
8.8
—
—
—
0
0
93
774
1.21
0.99
2.9
2.3
38.3
37.8
g/l
0.31
80
672
24
164
1.47
0.99
1.0
1.0
—
—
—
0
0
22
320
0.69
0.98
1.2
1.2
—
—
—
0
0
9
159
0.56
0.98
18.0
12.5
834.3
844.0
nmol/l
—
9
153
20
133
1.51
0.94
1.5
1.4
—
—
—
0
0
92
770
1.20
0.94
1.1
1.2
—
—
—
0
0
42
323
1.30
0.89
1.5
1.5
—
—
—
0
0
75
903
0.83
0.88
8.3
9.4
—
—
—
0
0
99
840
1.18
0.88
1.3
1.2
—
—
—
0
0
19
127
1.50
0.88
2.3
3.3
—
—
—
0
0
17
111
1.53
0.87
2.1
1.9
—
—
—
0
0
86
722
1.20
0.87
1.2
1.5
472.8
518.1
mg/l
0.49
81
685
30
221
1.36
0.85
2.0
2.2
18.0
12.4
%
0.98
15
105
8
45
1.78
0.84
2.0
1.7
—
—
—
0
0
30
222
1.35
0.83
1.3
1.4
10.2
12.2
mmol/l
—
10
52
59
479
1.24
0.83
1.5
1.6
—
—
—
0
0
117
1014
1.16
0.82
1.1
1.1
—
—
—
0
0
12
73
1.65
0.81
2.0
1.4
—
—
—
0
0
20
138
1.45
0.81
2.2
3.1
—
—
—
0
0
228
2067
1.11
0.80
1.3
1.4
—
—
—
0
0
0
24
0.00
0.79
0.0
1.5
—
—
—
0
0
37
286
1.30
0.78
1.5
2.0
—
—
—
0
0
10
163
0.61
0.78
30.5
16.8
1735.3
1530.3
nmol/l
—
10
158
43
340
1.27
0.77
5.0
6.8
11.4
11.6
mg/l
0.09
38
319
428
4007
1.08
0.76
3.1
3.0
0.7
0.7
ug/l
0.55
290
2601
9
53
1.70
0.75
1.3
1.3
—
—
—
0
0
5
24
2.08
0.74
1.2
1.2
—
—
—
0
0
43
342
1.26
0.74
2.7
2.8
—
—
—
0
0
9
54
1.67
0.74
1.0
1.0
—
—
—
0
0
9
54
1.67
0.74
1.0
1.0
—
—
—
0
0
9
54
1.67
0.74
1.0
1.0
—
—
—
0
0
32
245
1.31
0.73
1.4
1.2
—
—
—
0
0
7
38
1.84
0.73
2.1
1.1
—
—
—
0
0
36
457
0.79
0.72
3.9
2.3
—
—
—
0
0
9
57
1.58
0.71
1.0
1.0
—
—
—
0
0
44
354
1.25
0.70
1.3
1.2
—
—
—
0
0
33
256
1.29
0.70
1.4
1.4
111608.5
100351.1
e6/l
0.05
21
142
52
427
1.22
0.69
1.2
1.3
—
—
—
0
0
58
482
1.21
0.69
1.0
1.1
—
—
—
0
0
151
1353
1.12
0.68
7.5
9.9
24.5
24.3
mmol/l
0.38
141
1275
78
667
1.17
0.68
3.9
4.0
24.4
24.8
mmol/l
0.45
66
580
175
1582
1.11
0.68
2.2
3.4
268.0
49.3
u/ml
0.62
169
1527
20
144
1.39
0.67
2.6
1.5
—
—
—
0
0
7
43
1.63
0.66
7.1
3.0
—
—
—
0
0
42
339
1.24
0.66
1.3
1.5
—
—
—
0
0
42
339
1.24
0.66
1.3
1.5
—
—
—
0
0
42
339
1.24
0.66
1.3
1.5
—
—
—
0
0
42
339
1.24
0.66
1.3
1.5
—
—
—
0
0
69
588
1.18
0.64
4.7
3.9
—
—
—
0
0
8
49
1.63
0.62
1.1
1.8
—
—
—
0
0
45
370
1.22
0.61
1.5
1.6
—
—
—
0
0
83
723
1.15
0.60
1.9
1.9
3.1
4.8
iu/l
1.18
27
254
17
122
1.40
0.60
1.7
1.6
—
—
—
0
0
8
52
1.54
0.59
1.6
2.2
2.4
2.6
mmol/l
—
8
47
0
23
0.00
0.58
0.0
2.0
—
17.4
—
0
23
36
291
1.24
0.58
1.4
1.4
2385.1
2411.7
e6/l
0.01
26
204
61
521
1.17
0.57
1.4
1.5
107.3
116.5
u/ml
0.24
13
95
26
202
1.29
0.57
2.3
2.2
—
—
—
0
0
141
1277
1.11
0.56
1.9
1.9
—
—
—
0
0
41
338
1.22
0.56
2.9
2.9
—
—
—
0
0
48
403
1.19
0.55
1.7
1.8
—
—
—
0
0
56
477
1.18
0.55
1.1
1.1
—
—
—
0
0
9
60
1.50
0.54
1.9
1.5
—
—
—
0
0
37
303
1.22
0.54
1.5
1.7
—
—
—
0
0
849
8214
1.05
0.52
3.3
3.2
7.5
7.5
mmol/l
0.13
735
6960
27
215
1.26
0.50
1.7
1.5
—
—
—
0
0
44
520
0.84
0.50
1.5
1.5
—
—
—
0
0
10
67
1.49
0.49
1.2
1.1
—
—
—
0
0
27
216
1.25
0.49
1.2
1.1
—
—
—
0
0
7
45
1.56
0.49
5.9
3.1
—
—
—
0
0
69
605
1.14
0.48
6.7
4.5
3.0
2.6
mmol/l
0.49
50
411
7
108
0.65
0.48
1.1
1.2
—
—
—
0
0
56
484
1.16
0.48
1.0
1.1
—
—
—
0
0
100
900
1.11
0.47
2.0
2.3
245.9
677.1
ug/l
1.09
93
838
64
562
1.14
0.45
1.4
1.3
300.2
259.4
u/ml
0.41
44
348
26
210
1.24
0.45
1.3
1.4
0.9
1.2
promille
0.42
18
165
67
591
1.14
0.44
1.3
1.6
—
—
—
0
0
12
86
1.40
0.44
2.3
2.9
—
130.9
—
0
18
16
121
1.32
0.44
1.2
1.1
—
—
—
0
0
13
95
1.37
0.43
1.6
2.4
110.0
282.0
e6/l
—
7
50
33
275
1.20
0.43
2.7
3.3
—
—
—
0
0
9
127
0.71
0.43
1.1
1.1
—
—
—
0
0
5
31
1.61
0.43
6.2
11.2
—
—
—
0
0
5
31
1.61
0.43
1.2
1.2
—
—
—
0
0
5
31
1.61
0.43
1.4
1.5
—
—
—
0
0
304
2883
1.06
0.43
1.4
1.4
—
—
—
0
0
6
92
0.65
0.42
1.3
1.1
—
—
—
0
0
20
251
0.80
0.42
1.3
1.4
39.3
34.4
%
0.24
15
148
16
122
1.31
0.42
1.8
2.5
8.1
11.1
%
0.70
16
113
6
94
0.64
0.42
1.5
1.8
—
—
—
0
0
5
33
1.52
0.41
1.0
1.1
—
—
—
0
0
8
59
1.36
0.41
1.9
1.4
—
—
—
0
0
15
114
1.32
0.40
1.8
2.4
22.2
27.6
%
1.20
15
106
16
123
1.30
0.40
1.6
2.3
18.8
83.2
ug/l
0.50
16
109
247
2334
1.06
0.40
3.9
3.9
—
—
—
0
0
0
18
0.00
0.40
0.0
3.1
—
—
—
0
0
0
18
0.00
0.40
0.0
1.4
—
373.2
—
0
18
49
428
1.15
0.39
2.8
3.4
1.6
1.3
%
0.20
41
338
44
506
0.87
0.39
1.5
1.4
—
—
—
0
0
80
722
1.11
0.38
5.7
5.1
8.5
8.5
kpa
0.04
72
668
48
419
1.15
0.38
1.2
1.2
45.3
33.6
u/l
0.31
39
359
28
233
1.20
0.38
1.4
1.5
—
—
—
0
0
44
505
0.87
0.38
1.5
1.4
—
—
—
0
0
62
695
0.89
0.38
1.2
1.3
—
—
—
0
0
189
1775
1.07
0.37
3.1
2.9
—
—
—
0
0
5
80
0.62
0.35
2.8
2.1
—
—
—
0
0
25
208
1.20
0.35
1.9
2.3
730.2
641.0
ml
0.41
17
142
21
255
0.82
0.35
1.5
1.4
2919.7
81393.7
e6/l
1.30
11
177
6
44
1.36
0.34
2.2
7.5
7258.6
66.9
g/mol
—
6
38
79
719
1.10
0.34
6.1
4.2
7.4
7.4
ph
0.38
67
598
12
91
1.32
0.33
1.1
1.1
—
4.3
—
0
12
53
472
1.12
0.33
3.2
3.3
—
—
—
0
0
6
87
0.69
0.33
1.3
1.3
61.9
49.3
%
—
6
75
20
164
1.22
0.32
2.1
2.8
41.4
41.1
%
—
7
54
20
164
1.22
0.32
1.7
1.4
99.7
240.2
pmol/l
—
6
54
24
202
1.19
0.31
1.5
2.5
898.4
740.8
e6/l
—
8
81
14
175
0.80
0.30
3.2
3.5
—
—
—
0
0
63
571
1.11
0.30
1.4
1.4
—
—
—
0
0
26
221
1.18
0.30
1.7
1.5
0.9
0.9
g/l
0.32
26
221
26
224
1.16
0.27
1.2
1.3
0.2
0.5
u/ml
—
8
93
11
86
1.28
0.26
1.0
1.0
—
—
—
0
0
5
74
0.68
0.26
1.0
1.3
26.8
17.6
umol/l
—
5
67
10
127
0.79
0.25
1.1
2.4
—
—
—
0
0
21
245
0.86
0.25
1.0
1.1
—
—
—
0
0
35
311
1.13
0.25
1.1
1.3
—
—
—
0
0
181
1728
1.05
0.24
1.4
1.4
—
—
—
0
0
51
464
1.10
0.24
1.0
1.1
—
—
—
0
0
96
899
1.07
0.24
1.3
1.3
274.4
218.3
miu/ml
0.65
45
435
9
77
1.17
0.24
1.4
1.6
—
—
—
0
0
46
418
1.10
0.23
1.5
1.7
—
—
—
0
0
5
39
1.28
0.23
1.0
1.6
30.9
36.1
pmol/l
—
5
33
14
168
0.83
0.22
1.3
1.6
51.2
23.8
umol/l
1.50
14
161
7
94
0.74
0.22
1.0
1.0
—
—
—
0
0
27
238
1.14
0.22
1.2
1.2
—
—
—
0
0
5
41
1.22
0.22
1.2
4.0
41.2
43.4
umol/l
—
5
33
15
178
0.84
0.22
1.3
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
4.5
—
—
—
0
0
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
8
104
0.77
0.21
1.3
7.0
116.8
72.0
mg/l
—
8
77
47
431
1.09
0.20
1.4
1.5
—
—
—
0
0
60
557
1.08
0.20
2.8
2.6
17.4
16.4
%
1.02
30
286
6
48
1.25
0.20
1.0
1.1
—
—
—
0
0
6
48
1.25
0.20
1.8
1.5
—
—
—
0
0
13
155
0.84
0.20
1.3
1.3
141.2
132.1
nmol/l
0.39
13
155
9
115
0.78
0.20
1.8
1.8
—
—
—
0
0
6
50
1.20
0.19
1.0
1.1
—
—
—
0
0
25
222
1.13
0.19
1.6
1.2
602.0
154.0
titre
—
5
45
6
53
1.13
0.18
1.2
1.2
—
—
—
0
0
67
714
0.94
0.18
3.3
2.6
—
—
—
0
0
980
9927
0.98
0.18
3.0
2.7
—
—
—
0
0
39
357
1.09
0.18
1.1
1.1
0.2
0.3
u/ml
—
7
97
62
580
1.07
0.18
3.4
3.1
31.7
36.7
umol/l
0.86
51
501
21
185
1.14
0.18
1.2
1.3
—
1.5
—
0
10
11
91
1.21
0.17
1.0
1.2
—
—
—
0
0
52
558
0.93
0.17
1.1
1.2
—
—
—
0
0
41
444
0.92
0.17
1.0
1.1
142.3
1285.4
iu/ml
—
6
104
8
68
1.18
0.16
2.3
1.9
—
—
—
0
0
85
807
1.05
0.16
3.0
3.3
—
—
—
0
0
8
71
1.13
0.16
2.0
2.4
—
—
—
0
0
33
302
1.09
0.16
3.1
4.2
—
—
—
0
0
76
801
0.95
0.15
2.5
1.9
—
—
—
0
0
15
130
1.15
0.15
2.9
1.6
—
—
—
0
0
31
284
1.09
0.15
1.1
1.1
—
—
—
0
0
61
576
1.06
0.14
3.7
3.7
16.3
26.0
mg/l
2.45
36
358
67
636
1.05
0.14
1.6
1.7
13238.3
12598.3
e6/l
0.07
46
463
9
110
0.82
0.13
3.9
2.7
—
—
—
0
0
30
324
0.93
0.12
1.3
1.6
43.5
59.7
%
1.76
21
203
27
249
1.08
0.12
1.6
1.6
—
—
—
0
0
100
1035
0.97
0.11
2.3
1.9
—
—
—
0
0
12
105
1.14
0.11
9.7
12.1
—
—
—
0
0
26
280
0.93
0.10
3.0
2.7
—
—
—
0
0
29
310
0.93
0.10
1.5
1.4
281.6
280.0
mosm/kgh2o
0.18
22
241
12
106
1.13
0.09
1.2
1.1
—
—
—
0
0
10
114
0.88
0.09
2.2
2.9
1.0
1.5
ug/l
—
10
107
16
145
1.10
0.09
2.3
2.2
2.1
1.9
umol/l
0.39
16
137
101
1040
0.97
0.09
2.3
1.9
—
—
—
0
0
17
155
1.10
0.09
1.1
1.1
—
—
—
0
0
54
563
0.96
0.09
2.6
3.7
—
—
—
0
0
6
56
1.07
0.08
1.0
1.1
—
—
—
0
0
22
204
1.08
0.08
2.0
2.4
0.3
2.0
u/field
—
8
94
6
57
1.05
0.08
3.0
1.7
—
—
—
0
0
100
1028
0.97
0.08
2.2
1.9
—
—
—
0
0
16
146
1.10
0.08
1.7
1.7
2.3
3.5
u/field
—
10
108
10
88
1.14
0.08
1.1
1.1
—
—
—
0
0
7
65
1.08
0.08
1.1
1.0
—
—
—
0
0
7
65
1.08
0.08
1.1
1.0
—
—
—
0
0
7
65
1.08
0.08
1.1
1.0
—
—
—
0
0
46
480
0.96
0.08
2.9
3.2
0.9
0.8
nmol/l
0.26
38
370
117
1143
1.02
0.07
1.1
1.1
—
—
—
0
0
15
137
1.10
0.07
2.2
2.2
31.2
28.4
umol/l
0.41
15
132
21
225
0.93
0.07
2.4
4.0
9.8
11.2
%
0.59
21
225
37
353
1.05
0.07
1.2
1.2
—
—
—
0
0
7
83
0.84
0.07
2.1
1.3
—
—
—
0
0
27
255
1.06
0.07
2.3
3.2
52.3
56.7
%
0.55
20
170
9
87
1.03
0.07
1.0
1.1
—
—
—
0
0
10
89
1.12
0.06
1.2
1.6
—
—
—
0
0
8
90
0.89
0.06
1.3
1.4
—
—
—
0
0
64
658
0.97
0.05
2.2
2.1
—
—
—
0
0
138
1357
1.02
0.05
3.8
4.9
24.6
24.0
mmol/l
1.39
123
1229
15
139
1.08
0.05
1.1
1.3
—
—
—
0
0
26
249
1.04
0.04
1.4
1.5
—
—
—
0
0
10
109
0.92
0.04
2.0
1.7
—
—
—
0
0
267
2692
0.99
0.04
1.3
1.3
—
—
—
0
0
94
954
0.98
0.03
2.3
1.9
—
—
—
0
0
13
122
1.07
0.02
1.1
1.1
1509.5
1510.6
miu/ml
0.00
13
122
16
152
1.05
0.02
1.2
1.2
—
—
—
0
0
32
311
1.03
0.02
2.5
2.4
—
—
—
0
0
28
272
1.03
0.02
1.3
1.2
—
—
—
0
0
55
559
0.98
0.02
1.6
2.2
0.9
0.8
nmol/l
0.16
47
464
47
478
0.98
0.01
1.5
1.5
59.5
62.8
mmol/l
0.19
34
386
17
177
0.96
0.01
1.0
1.0
606.5
709.8
ng/l
0.48
11
111
769
7700
1.00
0.01
1.4
1.4
—
—
—
0
0
11
116
0.95
0.00
3.0
2.8
—
—
—
0
0
13
136
0.96
0.00
1.4
2.1
—
—
—
0
0
14
134
1.04
0.00
1.6
2.9
7.4
7.4
ph
—
5
45
16
166
0.96
0.00
1.0
1.2
—
—
—
0
0
29
296
0.98
0.00
2.4
2.3
—
—
—
0
0
102
1019
1.00
0.00
2.2
1.8
—
—
—
0
0
13
131
0.99
0.00
1.6
1.3
—
—
—
0
0
255
2549
1.00
0.00
1.6
1.6
—
—
—
0
0
197
1970
1.00
0.00
2.7
2.9
4.4
4.1
e9/l
0.77
153
1575
71
710
1.00
0.00
1.3
1.5
62.3
184.0
pmol/l
3.93
71
697
31
309
1.00
0.00
1.5
1.5
—
25.4
—
0
17
14
138
1.01
0.00
1.7
1.9
—
—
—
0
0
160
1598
1.00
0.00
1.7
1.7
—
—
—
0
0
30
296
1.01
0.00
1.1
1.2
—
—
—
0
0
9
96
0.94
0.00
1.1
1.3
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
5
56
0.89
0.00
1.8
2.2
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
2.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.8
—
—
—
0
0
8
81
0.99
0.00
4.5
7.6
26.7
24.6
mmol/l
—
8
74
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.7
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
157.0
—
0
7
0
5
0.00
0.00
0.0
1.6
—
2984.0
—
0
5
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
123.0
—
0
6
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
7
79
0.89
0.00
1.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint CD2_BENIGN_HEMANGIOMA and mortality.

Females

Parameter HR [95% CI] p-value
CD2_BENIGN_HEMANGIOMA 0.895 [0.79, 1.01] 0.068
Birth year 0.995 [0.99, 1.0] 0.296

During the follow-up period (1.1.1998 — 31.12.2019), 908 out of 12925 females with CD2_BENIGN_HEMANGIOMA died.

Males

Parameter HR [95% CI] p-value
CD2_BENIGN_HEMANGIOMA 1.118 [0.99, 1.26] 0.063
Birth year 0.988 [0.98, 1.0] 0.015

During the follow-up period (1.1.1998 — 31.12.2019), 1068 out of 8426 males with CD2_BENIGN_HEMANGIOMA died.

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_HEMANGIOMA.

N-year risk Females Males
1 0.073% 0.267%
5 0.493% 1.405%
10 1.323% 3.493%
15 2.585% 6.38%
20 4.613% 11.073%

Relationships between endpoints

Index endpoint: CD2_BENIGN_HEMANGIOMA – Haemangioma, any site

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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