Risteys ·

OMOP concept ID	Test name	Measurement unit (harmonized unit)	N people	N records	Missing measurement value	Harmonized value distribution
3001467	s-afluust	u/l (u/l)	2205	2705	0.00%
3001467	luusto-is	u/l (—)	864	979	100.00%	Distribution not available
3001467	afosluusto	u/l (u/l)	518	581	0.00%
3001467	s-afluust	— (—)	337	361	100.00%	Distribution not available
3001467	afosluusto	— (—)	138	145	100.00%	Distribution not available
3001467	s-afosluu	u/l (u/l)	97	105	0.00%
3001467	s-luust	u/l (—)	91	100	100.00%	Distribution not available
3001467	afosluu	u/l (u/l)	76	90	0.00%
3001467	alkalinenfosfataasi(afos)	u/l (u/l)	18	18	0.00%
3001467	alkalinenfosfataasi(afos)	— (—)	6	6	100.00%	Distribution not available

LabWAS

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

Care involving dialysis

316

187

18.73

307.65

1.4

1.1

76.08

75.48

u/l

0.01

215

124

Chronic kidney disease

621

858

7.51

307.65

1.3

1.2

66.11

70.84

u/l

0.35

421

577

Renal failure

780

1331

5.53

307.65

1.2

65.23

65.68

u/l

0.03

538

878

Dialysis, with operation codes

418

351

12.88

307.65

1.4

1.2

74.62

72.39

u/l

0.07

304

242

Nephropathy related operations

393

364

11.66

307.65

1.4

1.2

76.80

71.56

u/l

0.19

293

250

ILD medications: immunosuppressive drugs

979

2108

4.55

307.65

1.2

74.58

63.19

u/l

1.12

726

1396

Diseases of liver

723

1264

5.95

307.65

1.2

52.89

65.17

u/l

3.30

512

832

Autoimmune diseases excluding thyroid diseases

1307

2115

3.48

305.41

1.2

57.81

74.18

u/l

3.28

935

1396

Autoimmune diseases excluding thyroid diseases, strict definition

1262

2032

3.51

299.12

1.2

57.56

74.98

u/l

3.40

905

1334

Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism

1262

2796

3.28

295.22

1.2

75.72

61.51

u/l

1.49

886

1854

Anaemias

393

243

11.03

290.82

1.3

1.2

73.32

66.97

u/l

0.31

287

154

First line medication for Crohn's disease

1333

2249

3.27

283.59

1.3

1.2

68.84

67.30

u/l

0.11

929

1492

Renal tubulo-interstitial diseases

1135

2649

3.34

277.82

1.2

66.33

65.33

u/l

0.08

792

1762

ILD medications

1352

2389

3.14

271.06

1.3

1.2

72.70

65.00

u/l

0.73

951

1596

Transplanted organ and tissue status

279

260

11.49

261.63

1.4

1.1

115.72

69.21

u/l

1.56

211

181

Other diseases of liver

410

620

6.94

259.35

1.3

1.2

54.67

62.51

u/l

0.99

283

421

ILD medications: prednisolone, methylprednisolone, prednisone

1290

2370

3.11

257.24

1.3

1.2

68.81

64.46

u/l

0.44

905

1578

Preparatory care for dialysis

198

105

21.59

256.83

1.4

1.2

75.19

54.99

u/l

1.59

118

Autoimmune diseases related-to ILD

1078

3051

3.15

250.48

1.2

56.32

67.90

u/l

3.53

756

2040

Extracorporeal dialysis

220

153

15.87

248.07

1.4

1.2

76.73

58.34

u/l

1.73

149

112

Other bacterial diseases

1171

2679

3.07

242.65

1.3

1.2

72.89

64.21

u/l

0.80

835

1763

Inflammatory bowel disease treatment related agents

1319

2640

2.87

230.40

1.2

64.72

67.88

u/l

0.29

925

1765

Glomerular disorders in diseases classified elsewhere

281

331

8.97

221.33

1.4

1.1

63.14

58.44

u/l

0.42

204

225

Bacterial infection, other or unspecified

717

1746

3.78

220.97

1.3

1.2

74.70

62.98

u/l

1.02

512

1138

L04AD Calcineurin inhibitors

272

324

8.90

212.45

1.4

1.1

115.96

62.63

u/l

1.94

207

226

Glomerular diseases

360

584

6.42

212.41

1.3

1.2

68.28

72.91

u/l

0.23

261

391

Fibrosis and cirrhosis of liver

227

223

11.01

205.75

1.3

1.1

47.02

55.33

u/l

1.44

161

157

GASTRO-related operations

809

1100

3.73

200.72

1.2

1.1

70.00

67.42

u/l

0.17

544

779

Any gastric operation

809

1100

3.73

200.72

1.2

1.1

70.00

67.42

u/l

0.17

544

779

Heart failure, not strict

932

2115

3.09

195.05

1.2

64.05

67.16

u/l

0.20

652

1408

Second line medication for Crohn's disease

751

2311

3.31

194.57

1.2

64.89

65.66

u/l

0.05

549

1513

Autoimmune diseases

1177

2141

2.84

194.50

1.2

60.96

74.33

u/l

2.23

808

1414

Secondary hypertension

207

192

11.28

192.14

1.3

1.1

72.60

69.12

u/l

0.20

129

120

Kidney transplant status

177

135

14.33

189.13

1.4

1.2

88.66

83.48

u/l

0.08

131

101

ILD medications: azathioprine

278

390

7.38

188.01

1.3

1.1

76.69

59.57

u/l

0.73

202

260

IBD patients in KELA-register

385

748

5.29

187.02

1.3

1.2

59.33

63.67

u/l

0.40

266

498

L04AA Selective immunosuppressants

392

799

5.07

180.55

1.3

1.1

75.41

63.06

u/l

0.98

307

525

Inflammatory bowel disease, strict (require KELA)

385

782

5.06

177.72

1.3

1.2

59.33

63.05

u/l

0.34

266

527

L04AX Other immunosuppressants

715

2268

3.21

176.22

1.2

65.42

65.64

u/l

0.01

530

1476

Azathioprine

278

422

6.82

174.80

1.3

1.1

76.69

60.24

u/l

0.70

202

280

Abnormal findings on examination of blood, without diagnosis

602

1597

3.60

174.60

1.2

58.90

65.75

u/l

0.75

420

1042

Oral corticosteroids

1124

2599

2.64

172.71

1.2

61.73

65.69

u/l

0.51

778

1729

Used for control exclusion in common control thyroid runs

1063

1937

2.81

172.48

1.2

61.74

76.10

u/l

2.13

725

1272

Primary biliary cholangitis (PBC)

123

26.30

171.88

1.3

1.0

45.91

53.30

u/l

0.64

Septicaemia

525

1341

3.84

168.80

1.3

1.1

77.26

61.35

u/l

0.80

382

849

Dialysis

145

16.29

166.00

1.4

1.2

85.81

97.06

u/l

0.12

Other septicaemia

478

1195

4.01

164.04

1.3

1.1

78.09

62.77

u/l

0.67

344

759

5-aminosalicylic acid

333

639

5.35

163.99

1.3

1.2

56.57

63.75

u/l

1.05

230

419

Bacterial Sepsis

568

1430

3.60

162.88

1.3

1.2

73.20

62.29

u/l

0.62

411

919

Inflammatory bowel disease

459

1162

4.04

159.91

1.3

1.2

59.01

63.47

u/l

0.52

320

767

Noninfective enteritis and colitis

597

1801

3.37

159.53

1.3

1.2

58.54

68.08

u/l

1.53

420

1188

Fever of other and unknown origin

634

1845

3.23

155.92

1.3

1.2

65.60

68.70

u/l

0.27

463

1201

Explicit Sepsis

535

1457

3.58

155.72

1.3

1.2

77.02

62.48

u/l

0.72

389

937

Polyarthropathies

816

1887

2.92

154.45

1.2

55.04

70.35

u/l

3.90

595

1255

Acute renal failure

310

590

5.41

154.31

1.2

67.80

68.02

u/l

0.01

215

390

Implicit bacterial Sepsis

508

1289

3.69

151.99

1.3

1.2

73.35

62.45

u/l

0.55

364

825

Aplastic and other anaemias

572

1633

3.38

151.75

1.3

1.2

71.51

64.79

u/l

0.33

397

1065

Insulin, fast-acting

471

1284

3.74

147.39

1.3

1.2

57.73

71.39

u/l

1.92

343

845

Mucosal proctocolitis

226

345

6.78

141.44

1.3

1.1

52.00

63.15

u/l

1.21

165

233

Reimbursement for rheumatic diseases

705

2507

2.85

141.33

1.2

53.89

64.74

u/l

3.10

516

1627

Any reimbursement code in KELA

501

615

4.12

141.14

1.2

1.1

69.67

65.01

u/l

0.24

352

390

Insulin, fast-acting or short human

473

1336

3.60

140.39

1.3

1.2

57.74

71.00

u/l

1.91

345

878

Persons encountering health services for specific procedures and health care

1098

2867

2.39

139.12

1.3

1.2

72.98

64.19

u/l

0.90

795

1900

Ulcerative colitis

360

846

4.36

138.77

1.3

1.2

59.57

63.54

u/l

0.35

249

557

Budesonide

238

395

6.23

137.20

1.4

1.1

55.82

58.20

u/l

0.23

157

264

Disorders resulting from impaired renal tubular function

126

14.64

135.76

1.3

1.2

75.47

85.51

u/l

0.12

Insulin, intermediate and long-acting

623

2081

2.98

135.20

1.2

56.18

67.84

u/l

2.18

437

1385

Dental caries

352

821

4.34

134.81

1.3

1.2

91.89

66.20

u/l

1.10

274

534

Ulcer of lower limb, not elsewhere classified

246

430

5.94

134.61

1.3

1.1

49.56

67.61

u/l

1.31

191

282

Other anaemias

513

1517

3.32

132.94

1.2

70.01

65.30

u/l

0.20

369

990

Disorders of parathyroid gland

342

790

4.40

132.44

1.3

1.2

76.88

57.29

u/l

3.82

251

507

Other and unspecified anaemias

506

1493

3.34

132.25

1.2

70.23

65.50

u/l

0.20

363

974

Diabetic nephropathy, excluding more controls

273

420

5.65

132.16

1.3

1.2

62.85

58.48

u/l

0.33

200

277

Implicit Sepsis

788

2327

2.66

131.65

1.2

67.77

62.93

u/l

0.31

546

1545

Insulin, combination of fast acting with intermediate-acting or long-acting

678

2256

2.81

130.30

1.3

1.2

57.84

67.95

u/l

1.81

480

1505

Nonalcoholic fatty liver disease

201

298

7.08

129.81

1.2

58.64

57.41

u/l

0.07

135

209

Other dialysis

117

15.00

127.27

1.4

1.2

64.74

98.92

u/l

0.42

Unspecified kidney failure

180

242

7.75

126.74

1.2

69.18

58.92

u/l

0.55

128

171

Insulin medication

678

2112

2.78

125.83

1.3

1.2

57.84

70.27

u/l

2.30

480

1427

Dentinal caries

320

736

4.42

125.82

1.3

1.2

74.41

67.32

u/l

0.38

246

478

Ulcerative colitis (strict definition, require KELA)

267

539

5.09

124.35

1.3

1.2

57.29

61.75

u/l

0.42

182

366

UC patients in KELA-register ( KELA 208 prior to 1994, or ICD K51)

280

590

4.87

123.92

1.3

1.2

57.18

62.94

u/l

0.60

191

402

Tramadol

830

2098

2.57

123.06

1.2

59.45

58.82

u/l

0.08

608

1366

Type 1 diabetes

336

820

4.17

122.82

1.3

1.2

57.56

69.81

u/l

2.06

246

549

Diabetic nephropathy

277

578

4.92

122.10

1.3

1.1

62.68

59.43

u/l

0.27

204

375

Ulcerative colitis (strict definition, require KELA, min 2 HDR)

259

518

5.14

121.96

1.3

1.2

57.60

62.38

u/l

0.43

176

350

Hyperparathyroidism

306

693

4.50

121.81

1.3

1.2

77.50

57.21

u/l

3.92

223

448

Disorders of gallbladder, biliary tract and pancreas

1014

2859

2.31

119.73

1.2

55.77

63.66

u/l

2.26

708

1907

Type 1 diabetes, wide definition, subgroup 1

285

629

4.62

118.81

1.3

1.2

56.52

68.50

u/l

1.69

208

422

Cholangitis (primary sclerosing, PSC)

142

155

9.68

118.78

1.3

1.2

53.92

57.38

u/l

0.21

101

107

Disorders of other endocrine glands

524

1718

3.05

118.46

1.2

74.14

65.94

u/l

0.86

380

1145

Abnormal serum enzyme levels

366

970

3.80

117.05

1.3

1.2

57.74

64.63

u/l

0.71

254

620

Crohn disease

211

368

5.91

115.58

1.3

1.2

62.65

66.23

u/l

0.18

150

248

Metabolic disorders

971

2624

2.32

115.07

1.2

65.25

64.29

u/l

0.09

691

1756

Heart failure,strict

555

1354

3.00

112.81

1.2

55.11

71.37

u/l

2.04

376

891

Persons with potential health hazards related to family and personal history and certain conditions influencing health status

949

2833

2.30

112.56

1.3

1.2

70.69

64.95

u/l

0.57

645

1926

Heart failure and antihypertensive medication

337

533

4.26

110.19

1.2

58.29

61.80

u/l

0.23

241

348

Osteopathies and chondropathies

615

2216

2.67

107.91

1.3

1.2

69.99

61.16

u/l

1.28

425

1472

Type 1 diabetes, wide definition

288

694

4.23

107.21

1.3

1.2

56.24

68.45

u/l

1.91

211

471

Malignant neoplasm of breast

631

1712

2.70

106.00

1.2

58.89

58.39

u/l

0.09

405

1175

Malignant neoplasm of breast, HER2-negative

619

1701

2.72

105.62

1.2

58.96

58.37

u/l

0.11

398

1163

General symptoms and signs

1030

2334

2.23

104.93

1.2

61.84

67.67

u/l

0.82

709

1549

Malignant neoplasm of breast, HER2-negative, excluding all cancers (controls excluding all cancers)

569

1314

2.88

104.17

1.2

59.32

57.62

u/l

0.34

363

891

Malignant neoplasm of breast, excluding all cancers (controls excluding all cancers)

569

1315

2.87

104.02

1.2

59.32

57.60

u/l

0.35

363

892

Certain infectious and parasitic diseases

938

2052

2.31

103.39

1.2

67.17

65.44

u/l

0.12

627

1365

Malignant neoplasm

878

2268

2.32

102.59

1.2

72.51

59.07

u/l

2.15

596

1513

Persons encountering health services for other counselling and medical advice, not elsewhere classified

1061

2840

2.15

102.54

1.2

64.62

65.92

u/l

0.13

804

1861

Influenza and pneumonia

999

3061

2.16

102.04

1.3

1.2

70.99

65.37

u/l

0.41

740

2012

COPD/asthma/ILD related pneumonia or pneumonia derived septicaemia

891

2481

2.27

100.87

1.3

1.2

62.30

65.99

u/l

0.45

669

1620

891

2481

2.27

100.87

1.3

1.2

62.30

65.99

u/l

0.45

669

1620

Ulcerative colitis, NAS

210

414

5.21

100.60

1.2

1.1

58.29

63.33

u/l

0.35

136

276

Diseases of oesophagus, stomach and duodenum

1016

2899

2.15

99.78

1.2

62.89

64.00

u/l

0.10

664

1995

Malignant neoplasm, excluding all cancers (controls excluding all cancers)

851

2195

2.31

98.90

1.2

71.46

59.88

u/l

1.73

582

1470

Malignant neoplasm, wide definition for exclusion, excluding all cancers (controls excluding all cancers)

851

2197

2.31

98.68

1.2

71.46

59.84

u/l

1.74

582

1472

Malignant neoplasm of breast, ER-positive, excluding all cancers (controls excluding all cancers)

440

1165

3.13

98.64

1.2

1.1

60.17

58.25

u/l

0.33

278

780

Malignant neoplasm, wide definition for exclusion

851

2198

2.31

98.58

1.2

71.46

59.85

u/l

1.74

582

1473

All pneumoniae

955

3076

2.16

98.37

1.3

1.2

72.71

65.42

u/l

0.55

711

2011

Hypertensive diseases (excluding secondary)

555

1136

2.87

98.29

1.3

1.2

71.78

66.26

u/l

0.26

411

735

Examination and observation for other reasons

610

1387

2.70

98.21

1.2

59.75

71.13

u/l

1.49

472

961

Condition for Implicit Sepsis (Organ dysfunction codes)

822

2637

2.29

98.02

1.2

67.52

64.92

u/l

0.15

571

1745

Pneumonias (Asthma/COPD co-morbidities)

948

3062

2.16

97.98

1.3

1.2

72.70

65.42

u/l

0.55

710

1995

Cirrhosis, broad definition used in the article https://doi.org/10.1101/594523

217

462

4.84

95.13

1.2

54.67

64.47

u/l

1.19

156

300

Complications of surgical and medical care, not elsewhere classified

933

3168

2.13

93.57

1.2

58.99

65.34

u/l

1.34

648

2125

Sub-endpoint used in defining T1D endpoints

343

1005

3.41

93.57

1.3

1.2

57.33

72.42

u/l

1.67

252

667

Nutritional anaemias

528

1949

2.67

93.50

1.2

67.35

60.97

u/l

0.60

379

1282

Other disorders of kidney and ureter

198

397

5.15

93.22

1.3

1.1

69.93

68.65

u/l

0.04

141

266

Pneumonia, organism unspecified

859

2856

2.19

92.95

1.3

1.2

72.74

65.90

u/l

0.44

629

1862

Ulcerative colitis (strict definition, all Crohn cases excluded)

203

424

4.91

90.90

1.3

1.1

56.43

63.54

u/l

0.63

139

288

Other Crohn's disease

131

180

7.57

90.56

1.3

1.1

65.75

59.38

u/l

0.26

125

Any event in cancer register

858

2326

2.21

89.62

1.2

70.75

59.36

u/l

1.71

588

1553

Pneumonia (excl. viral and due to other infectious organisms not elsewhere classified)

914

3077

2.10

88.50

1.3

1.2

72.56

65.66

u/l

0.49

683

2007

Hypertension

764

1884

2.31

88.02

1.2

70.34

69.55

u/l

0.04

554

1230

Hypertensive diseases

764

1885

2.31

87.96

1.2

70.32

69.52

u/l

0.04

554

1231

Hypertension, essential

749

1853

2.33

87.53

1.2

60.04

66.42

u/l

0.90

542

1204

Heart failure, strict

580

1660

2.55

87.07

1.2

54.85

68.26

u/l

1.85

393

1098

L02BG Aromatase inhibitors

397

1355

3.00

86.92

1.2

60.66

58.16

u/l

0.50

250

914

Acute tubulo-interstitial nephritis

586

2127

2.47

86.85

1.2

67.72

62.66

u/l

0.35

414

1408

Insulin, fast-acting (human)

191

394

4.96

86.74

1.3

1.1

57.45

62.92

u/l

0.40

142

261

Iron deficiency anaemia

448

1625

2.77

85.45

1.2

69.26

61.38

u/l

0.64

321

1064

Persons encountering health services in other circumstances, wide

1087

2852

1.99

84.44

1.2

65.12

65.87

u/l

0.07

792

1871

Finngen Rheumatological endpoints

874

2353

2.13

83.37

1.2

61.30

67.80

u/l

1.02

604

1598

Implicit viral Sepsis

230

568

4.13

83.20

1.3

1.1

61.69

66.14

u/l

0.38

164

376

Viral Sepsis

230

572

4.10

82.41

1.3

1.1

61.69

66.06

u/l

0.38

164

378

All-cause Heart Failure

564

1638

2.51

82.40

1.2

55.49

68.46

u/l

1.69

379

1082

Malignant neoplasm of breast, HER-positive

437

1591

2.76

82.29

1.2

59.77

58.85

u/l

0.15

275

1070

Cholangitis (primary sclerosing, PSC), with reimbursement 202

15.95

82.19

1.2

45.83

55.77

u/l

0.91

Other heart diseases

473

1139

2.77

82.01

1.2

79.48

69.51

u/l

0.38

358

736

Medicines for HER+ breast cancer

445

1640

2.69

79.66

1.2

59.97

58.72

u/l

0.22

282

1106

Malaise and fatigue

479

1543

2.62

78.96

1.2

55.81

64.25

u/l

1.68

348

993

Opioids

884

2233

2.09

78.67

1.2

62.56

60.64

u/l

0.25

607

1470

Erysipelas

508

1886

2.48

76.79

1.2

61.97

61.76

u/l

0.01

376

1236

Other and unspecified iron deficiency

352

1205

2.97

76.39

1.2

73.55

63.15

u/l

0.69

253

781

Gout, FINNGEN

294

909

3.29

76.06

1.2

59.44

64.72

u/l

0.50

200

586

Other diseases of intestines

932

2722

2.00

75.99

1.2

63.62

69.28

u/l

0.44

631

1861

Oedema, not elsewhere classified

338

1131

3.02

75.62

1.2

53.53

63.43

u/l

2.21

206

734

Gout

294

822

3.31

75.27

1.2

59.44

70.06

u/l

0.75

200

539

Hernia of abdominal wall, postoperative

172

368

4.75

74.70

1.3

1.1

63.95

67.16

u/l

0.10

121

265

Oxycodone

368

1261

2.86

74.43

1.3

1.2

98.50

58.79

u/l

2.07

264

816

Other disorders of fluid, electrolyte and acid-base balance

330

1066

3.03

73.90

1.2

65.41

61.41

u/l

0.28

228

690

Other disorders of skin and subcutaneous tissue

663

2828

2.17

73.32

1.2

56.53

64.01

u/l

1.71

464

1873

Crohn's disease NAS

114

171

6.92

72.78

1.3

1.2

63.27

60.90

u/l

0.08

124

Cardiovascular diseases (excluding rheumatic etc)

549

1310

2.44

71.53

1.2

79.63

69.43

u/l

0.46

413

861

Chronic hepatitis, not elsewhere classified

9.64

71.48

1.2

1.1

48.80

53.42

u/l

0.42

Diseases of arteries, arterioles and capillaries (FINNGEN)

280

572

3.47

71.44

1.3

1.2

66.48

62.82

u/l

0.27

204

357

Pain in limb

705

2418

2.13

70.74

1.2

61.74

68.22

u/l

0.94

492

1629

Endocrine, nutritional and metabolic diseases

666

1522

2.24

69.49

1.2

65.94

72.34

u/l

0.56

481

1013

Hypothyroidism (congenital or acquired)

201

254

4.58

68.48

1.2

56.94

63.09

u/l

0.55

138

161

Chronic periodontitis

197

505

3.99

67.90

1.4

1.2

62.09

59.98

u/l

0.15

142

325

Infections, IBD-co-morbidities

178

282

4.67

67.90

1.3

1.2

63.42

71.36

u/l

0.24

132

182

Diarrhoea and gastroenteritis of presumed infectious origin

620

2635

2.15

67.60

1.2

75.84

65.65

u/l

0.53

446

1758

Hypothyroidism, levothyroxine purchases

199

253

4.56

67.47

1.2

56.56

63.35

u/l

0.63

136

160

Hypothyroidism and >3 levothyroxin purchases

199

253

4.56

67.47

1.2

56.56

63.35

u/l

0.63

136

160

Gastrointestinal diseases

477

931

2.58

66.92

1.2

69.34

70.24

u/l

0.04

338

611

Diseases of the skin and subcutaneous tissue

880

2247

1.98

66.58

1.2

62.76

68.89

u/l

0.77

587

1519

Complications of medical and surgical care

674

3128

2.06

66.04

1.2

56.72

63.04

u/l

1.48

459

2100

Osteoporosis

305

994

2.98

65.95

1.2

1.1

66.37

56.06

u/l

1.94

204

666

Colitis, primary sclerosing

17.37

65.86

1.3

53.07

53.22

u/l

0.01

Intestinal infectious diseases

816

3282

1.95

65.74

1.2

68.99

64.66

u/l

0.26

592

2186

Diabetes, varying definitions

903

2835

1.92

65.40

1.2

65.95

65.82

u/l

0.01

627

1908

Exposure to unspecified factor

840

3407

1.93

65.39

1.2

62.61

67.75

u/l

0.76

583

2308

Chronic periapical parodontitis

240

723

3.38

64.92

1.3

1.2

78.23

59.20

u/l

1.09

161

466

Amputation

139

281

5.09

64.85

1.3

1.2

50.21

59.82

u/l

0.90

103

191

Diseases of pulp and periapical tissues

349

1301

2.72

64.60

1.3

1.2

71.02

60.98

u/l

0.74

240

847

Other heart diseases, wide

801

2525

1.98

64.47

1.2

70.43

68.10

u/l

0.11

568

1679

Crohn's disease patients in KELA-register (KELA code 209, or 208 with ICD K50)

113

192

6.09

63.85

1.2

64.99

62.15

u/l

0.09

136

Complications of procedures, not elsewhere classified

713

3092

2.01

63.83

1.2

58.50

64.08

u/l

1.00

509

2073

Codeine

795

2198

2.00

63.78

1.2

58.08

60.16

u/l

0.36

559

1438

Crohn's disease of large intestine

142

7.11

63.43

1.3

1.2

73.90

68.10

u/l

0.16

Disorders of mineral metabolism

126

240

5.42

63.03

1.3

1.2

78.50

61.06

u/l

0.94

155

Gout, strict definition

194

519

3.82

62.92

1.2

58.28

70.03

u/l

0.89

128

333

Cholelithiasis, broad definition with cholecystitis

771

2695

1.98

62.90

1.2

53.48

62.22

u/l

2.52

529

1788

Cirrhosis of liver, NAS

141

7.15

62.72

1.2

48.43

53.48

u/l

0.37

101

Diabetes mellitus

897

2848

1.89

62.59

1.2

65.48

66.06

u/l

0.03

622

1917

Glomerulonephritis

139

290

4.93

62.55

1.3

1.2

80.40

76.71

u/l

0.09

104

199

Colitis, primary sclerosing, strict definition

21.76

62.47

1.2

43.62

60.38

u/l

1.46

Crohn disease (strict definition, require KELA)

109

185

6.10

61.70

1.2

65.21

62.30

u/l

0.09

131

Other retinal disorders

579

2182

2.15

61.33

1.3

1.2

60.26

65.18

u/l

0.64

369

1475

Diabetes, insuline treatment (Kela reimbursement), excluding more controls

853

2750

1.91

61.31

1.2

64.49

65.78

u/l

0.07

578

1848

Other inflammatory liver diseases

109

187

6.04

61.03

1.2

1.1

49.61

55.97

u/l

0.53

133

IBD (strict) with PSC

23.22

60.16

1.2

1.3

44.50

60.13

u/l

1.18

Other noninfective gastroenteritis and colitis

263

875

3.05

60.14

1.2

59.36

70.37

u/l

0.87

185

575

Diseases of the digestive system

427

1808

2.38

60.11

1.3

1.2

63.92

67.28

u/l

0.27

317

1182

Other soft tissue disorders, not elsewhere classified

777

2475

1.95

59.98

1.2

62.72

70.20

u/l

1.02

539

1674

Crohn disease (strict definition, require KELA, min 2 HDR)

106

181

6.06

59.63

1.2

65.81

62.70

u/l

0.10

128

Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure

561

2661

2.12

59.60

1.2

56.91

61.99

u/l

1.10

383

1774

Peripheral artery operations in Hilmo

157

379

4.23

58.69

1.3

1.2

50.10

64.50

u/l

1.72

114

258

Cholelithiasis

739

2675

1.95

58.61

1.2

53.41

62.30

u/l

2.53

505

1774

Osteomyelitis

100

165

6.28

58.26

1.4

1.1

54.23

62.43

u/l

0.49

110

Bleeding

727

2729

1.95

58.18

1.2

61.81

63.99

u/l

0.29

519

1803

Disorders of choroid and retina

716

2683

1.96

57.79

1.2

58.53

64.01

u/l

0.98

452

1829

Crohn's disease of small intestine

105

185

5.86

57.14

1.4

1.2

59.33

59.65

u/l

0.02

133

Diseases of arteries, arterioles and capillaries

593

2141

2.09

57.10

1.2

58.41

62.25

u/l

0.48

430

1406

Other and unspecified polyneuropathies, also in other diseases

212

644

3.36

56.71

1.2

49.75

66.68

u/l

3.51

147

425

Gout, unspecified

207

620

3.40

56.61

1.2

59.15

67.07

u/l

0.59

140

398

Diabetes, insulin treatment (Kela reimbursement)

880

2949

1.84

56.50

1.2

63.99

65.66

u/l

0.10

597

1989

Gout, idiopatic and unspecified

242

798

3.08

56.38

1.2

59.19

65.40

u/l

0.52

162

512

Heart failure and bmi 25plus

341

888

2.68

56.35

1.2

55.23

62.53

u/l

0.61

233

552

Pain in joint

507

1518

2.23

56.19

1.2

55.07

74.97

u/l

4.02

344

1004

Amputation of toe

106

193

5.68

55.77

1.3

1.1

50.40

59.54

u/l

0.70

128

Nausea and vomiting

266

917

2.89

55.24

1.3

1.2

83.61

69.67

u/l

0.33

179

603

Diabetes medication

877

2945

1.82

54.73

1.2

58.62

65.89

u/l

1.76

597

1988

Type 2 diabetes, wide definition

713

2418

1.94

54.44

1.2

56.10

65.87

u/l

2.39

481

1627

Deposits [accretions] on teeth

100

168

5.92

54.41

1.2

121.68

83.28

u/l

0.38

111

Acute peritonitis

101

180

5.81

54.38

1.3

1.2

71.50

60.79

u/l

0.74

121

Sulfasalazine

285

1051

2.75

54.01

1.2

55.73

61.66

u/l

1.06

214

688

Other diseases of biliary tract

120

251

4.92

53.92

1.3

1.2

59.08

58.38

u/l

0.04

102

170

Other diseases of blood and blood-forming organs, wide

247

846

2.97

53.88

1.2

87.96

63.12

u/l

1.05

181

562

Ulcerative ileocolitis

111

7.43

53.68

1.1

1.2

52.18

57.05

u/l

0.32

Abnormal findings on diagnostic imaging and in function studies, without diagnosis

570

2621

2.03

53.55

1.2

58.26

62.34

u/l

0.54

375

1753

ICD-8 DM (Sub-endpoint used for defining DM endpoints)

106

7.59

53.30

1.4

1.2

64.86

52.29

u/l

0.89

Benign neoplasm of colon, rectum, anus and anal canal

459

1467

2.26

53.28

1.2

56.82

58.04

u/l

0.13

305

958

Abnormalities of breathing

740

2317

1.91

53.19

1.2

56.03

71.43

u/l

4.11

508

1541

Disorders of thyroid, IBD co-morbidities

171

321

3.93

52.96

1.2

76.68

67.00

u/l

0.32

120

203

Polyneuropathies and other disorders of the peripheral nervous system

227

749

3.08

52.89

1.2

49.63

68.05

u/l

4.21

158

487

Direct fill therapy

161

428

3.84

52.77

1.3

1.2

78.19

65.33

u/l

0.54

120

297

Other arthritis (FG)

297

1132

2.66

52.75

1.2

50.55

64.37

u/l

4.28

236

746

Benign neoplasm: Colon

411

1365

2.33

52.25

1.2

1.1

54.23

57.77

u/l

0.57

274

878

Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity

111

225

5.08

51.77

1.3

1.2

53.16

59.33

u/l

0.49

153

Infections of the skin and subcutaneous tissue

486

2304

2.12

51.70

1.3

1.2

66.67

70.06

u/l

0.24

350

1545

Anaemia in chronic diseases classified elsewhere

10.85

51.59

1.3

1.1

77.54

115.59

u/l

0.28

Chronic periodontitis, complicated

128

295

4.46

51.07

1.5

1.2

60.55

58.86

u/l

0.10

202

Neoplasms

557

1428

2.10

50.84

1.2

69.13

68.41

u/l

0.04

395

976

Diabetic retinopathy, strict definition

222

641

3.11

50.62

1.3

1.2

56.61

60.84

u/l

0.42

142

436

Abnormal results of function studies

115

245

4.82

50.55

1.3

1.1

51.59

60.79

u/l

0.71

175

Codeine or tramadol medication

947

3020

1.75

50.43

1.2

61.23

63.15

u/l

0.23

671

2003

Gastro-oesophageal reflux disease

582

2629

1.98

50.20

1.2

62.55

62.38

u/l

0.01

350

1795

Cardiovascular diseases

452

1089

2.27

50.09

1.2

81.64

73.24

u/l

0.28

340

718

Continuous positive airway pressure

192

499

3.37

50.00

1.2

54.06

74.43

u/l

1.89

114

338

Rheumatoid arthritis

329

1227

2.47

49.18

1.2

53.83

64.18

u/l

2.69

248

799

Hyperkalaemia

132

6.43

48.99

1.3

1.2

80.32

54.55

u/l

0.77

Spondyloarthritis

178

531

3.40

48.96

1.2

51.32

59.23

u/l

0.96

134

353

Noninfectious colitis NAS

151

405

3.80

48.89

1.2

1.1

61.16

64.99

u/l

0.14

275

Medical observation and evaluation for suspected diseases and conditions

561

1394

2.07

48.84

1.3

1.2

64.01

71.03

u/l

0.64

355

967

Hypothyroidism, drug reimbursement

124

187

4.79

48.68

1.2

58.00

59.16

u/l

0.07

116

COPD/asthma/ILD related infections

878

2485

1.78

48.59

1.3

1.2

59.23

65.95

u/l

1.24

622

1623

COPD/asthma related infections

878

2485

1.78

48.59

1.3

1.2

59.23

65.95

u/l

1.24

622

1623

Peripheral artery disease

394

1403

2.28

48.39

1.2

53.92

64.46

u/l

1.38

292

905

Systemic connective tissue disorders

351

1510

2.35

48.16

1.2

56.04

61.43

u/l

0.53

246

1004

Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure

511

2547

2.02

48.07

1.2

56.38

61.80

u/l

1.17

347

1691

Disorders of lipoprotein metabolism and other lipidaemias

693

2340

1.87

47.79

1.2

55.55

64.67

u/l

1.85

474

1567

Dermatitis and eczema

883

3363

1.73

47.37

1.2

59.54

68.22

u/l

1.84

595

2295

Ascites

100

201

5.12

47.14

1.3

1.2

54.95

60.42

u/l

0.39

146

Chronic pancreatitis

140

367

3.90

46.90

1.2

56.22

65.58

u/l

1.00

245

Diabetic retinopathy, excluding more controls

279

572

2.79

46.75

1.3

1.2

56.33

58.96

u/l

0.25

180

387

Asthma, excluding more controls

598

1617

1.98

46.73

1.2

56.71

70.65

u/l

2.80

434

1054

Ulcerative colitis (strict) with PSC

26.43

46.46

1.2

42.75

72.11

u/l

—

Type 2 diabetes

815

2759

1.76

45.73

1.2

57.61

63.89

u/l

1.38

556

1854

Ulcerative rectosigmoiditis

102

215

4.86

45.40

1.4

1.1

52.59

56.13

u/l

0.34

146

Asthma, unspecified (mode), excluding more controls

415

1511

2.17

45.17

1.2

55.25

69.45

u/l

2.66

299

976

Biological medication for rheuma

171

526

3.31

44.92

1.2

51.70

62.22

u/l

1.47

132

361

Disorders of calcium metabolism

180

5.28

44.78

1.3

1.2

79.15

60.26

u/l

0.82

116

Other specific joint derangements/joint disorders

571

1981

1.94

44.67

1.2

56.38

73.33

u/l

3.86

389

1329

Seropositive rheumatoid arthritis

258

995

2.62

44.65

1.2

54.56

60.64

u/l

1.13

196

667

Other specified/unspecified arthritis

262

1021

2.60

44.61

1.2

50.89

67.08

u/l

4.23

211

657

Atrial fibrillation and flutter

299

774

2.55

44.30

1.2

62.74

68.17

u/l

0.34

221

494

Cardiac arrhythmias

501

1639

2.03

44.28

1.2

71.12

69.78

u/l

0.05

355

1079

Other ulcerative colitis

153

5.66

44.20

1.3

1.2

77.04

57.44

u/l

0.61

106

Primary_lymphoid and hematopoietic malignant neoplasms

214

758

2.86

43.89

1.2

74.94

64.43

u/l

0.44

163

490

Dyspnoea

731

3189

1.77

43.42

1.2

54.72

65.76

u/l

3.58

498

2141

Fall on same level

917

3052

1.69

43.41

1.3

1.2

71.44

66.19

u/l

0.37

615

2088

Diseases of peritoneum

128

334

3.92

43.24

1.2

68.18

58.03

u/l

1.03

224

Constipation

735

3000

1.77

43.04

1.2

61.33

63.96

u/l

0.28

502

2011

Hypothyroidism, strict autoimmune

526

1773

1.98

43.00

1.2

57.42

65.51

u/l

1.58

344

1134

Explicit bacterial Sepsis

108

252

4.37

42.34

1.4

1.1

71.42

63.01

u/l

0.29

174

Cutaneous abscess, furuncle and carbuncle

234

889

2.66

41.99

1.2

67.55

61.70

u/l

0.38

175

603

Vitreous haemorrhage

122

316

3.95

41.67

1.4

1.2

63.82

60.77

u/l

0.18

218

Certain disorders involving the immune mechanism

204

727

2.85

41.52

1.2

79.30

65.10

u/l

0.29

154

489

Hypertensive Renal Disease

7.81

41.39

1.2

1.3

61.02

75.02

u/l

0.48

Antihypertensive medication - note that there are other indications

435

1131

2.12

40.77

1.2

75.44

72.09

u/l

0.11

323

749

Adjustment and management of implanted device

169

551

3.11

40.30

1.2

1.1

55.66

74.68

u/l

1.06

140

355

Asthma

610

1763

1.87

40.16

1.2

56.90

68.89

u/l

2.45

446

1156

Tumor necrosis factor alpha inhibitors

149

456

3.32

39.53

1.1

1.2

52.89

63.91

u/l

1.33

117

316

Oesophageal varices

120

6.08

39.40

1.2

71.53

51.67

u/l

1.41

Other nutritional deficiencies

517

2705

1.88

39.36

1.2

61.47

62.18

u/l

0.06

352

1811

Benign neoplasms

523

1534

1.94

39.14

1.2

64.22

62.83

u/l

0.11

362

1038

Asthma, unspecified (mode)

420

1644

2.04

38.97

1.2

55.15

67.34

u/l

2.29

302

1068

Symptoms and signs involving the digestive system and abdomen

791

2321

1.72

38.91

1.2

66.24

69.64

u/l

0.25

534

1570

Dermatitis

501

2670

1.89

38.85

1.3

1.2

58.84

63.89

u/l

0.64

330

1779

Atherosclerosis, excluding cerebral and coronary sclerosis

350

1298

2.18

38.38

1.2

57.93

64.67

u/l

0.60

255

835

Benzodiazepine use

791

3382

1.67

38.27

1.2

58.74

65.02

u/l

1.04

520

2312

Pain, not elsewhere classified

238

955

2.52

38.18

1.3

1.2

53.88

65.38

u/l

2.05

181

622

Parasetamol

597

1652

1.85

38.09

1.2

62.63

68.01

u/l

0.53

415

1129

Congenital malformations of the urinary system

164

5.08

37.93

1.3

1.2

94.67

79.50

u/l

0.27

121

Amputation of foot

8.51

37.92

1.3

1.2

51.03

49.24

u/l

0.10

Respiratory diseases principally affecting the interstitium, IBD co-morbidites

108

188

4.29

37.66

1.1

1.2

56.54

58.08

u/l

0.09

120

Other and unspecified dermatitis

427

2182

1.97

37.63

1.2

59.94

62.19

u/l

0.22

284

1440

Non-ischemic cardiomyopathy

266

913

2.42

37.49

1.2

60.33

68.06

u/l

0.42

180

594

Chronic nephritic syndrome

109

6.19

37.38

1.3

1.2

93.20

53.15

u/l

1.53

Streptococcal septicaemia

197

4.61

37.38

1.4

1.1

71.04

68.74

u/l

0.06

136

Other diseases of the digestive system

273

1178

2.34

37.31

1.2

62.35

67.45

u/l

0.43

209

763

Other diseases of pancreas

210

4.49

37.25

1.2

58.99

59.84

u/l

0.04

150

Enterocolitis due to Clostridium difficile

116

314

3.77

37.20

1.3

1.1

63.03

55.61

u/l

0.55

213

Disorders of lens

587

2052

1.82

36.92

1.3

1.2

61.51

63.60

u/l

0.20

420

1369

Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified (FINNGEN)

366

1093

2.14

36.63

1.3

1.2

63.67

62.28

u/l

0.12

253

699

Low back pain

581

2508

1.79

36.60

1.2

56.09

64.53

u/l

2.46

412

1669

Other systemic involvement of connective tissue (FG)

237

964

2.47

36.41

1.2

57.21

61.64

u/l

0.30

171

643

Fracture of femur

230

841

2.52

36.41

1.3

1.1

72.07

57.96

u/l

1.49

169

550

Asthma (only as main-diagnosis), excluding more controls

512

1617

1.90

36.41

1.2

57.77

70.65

u/l

2.31

379

1054

Abdominal and pelvic pain

777

2320

1.69

36.40

1.2

62.91

69.34

u/l

0.58

537

1569

Cystic kidney disease

106

6.22

36.20

1.3

1.2

81.20

54.71

u/l

1.07

Asthma (mode)

587

1782

1.82

35.97

1.2

57.09

68.85

u/l

2.39

426

1166

Pain in throat and chest

644

2255

1.75

35.92

1.2

58.72

68.51

u/l

2.13

464

1489

Pure hypercholesterolaemia

578

2167

1.80

35.84

1.2

55.07

63.63

u/l

1.42

376

1445

Cholecystectomy

591

2989

1.76

35.65

1.2

55.38

59.87

u/l

1.04

413

1983

Diabetic retinopathy

327

941

2.22

35.64

1.3

1.2

56.00

58.61

u/l

0.30

212

651

GI-bleeding

268

1171

2.31

35.59

1.2

62.23

66.51

u/l

0.35

210

761

Alcoholic liver disease

105

274

3.91

35.52

1.2

1.1

56.32

61.51

u/l

0.37

182

Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified

263

527

2.52

35.47

1.2

1.1

58.53

71.63

u/l

1.35

188

336

Benign neoplasm of other and ill-defined parts of digestive system

164

567

2.94

35.37

1.2

1.1

54.43

60.62

u/l

0.71

126

356

Crohn disease (strict definition, all UC cases excluded)

144

5.22

35.25

1.2

55.90

60.62

u/l

0.30

103

Rheumatoid arthritis, including avohilmo

353

1729

2.06

35.17

1.2

54.70

62.17

u/l

1.94

266

1131

Other functional intestinal disorders

366

1723

2.04

35.16

1.2

59.67

67.49

u/l

1.08

255

1160

Other bacterial intestinal infections

169

596

2.88

35.12

1.2

62.62

62.36

u/l

0.01

124

396

Other diseases of intestine

128

385

3.38

35.00

1.3

1.2

95.72

61.54

u/l

0.46

261

Other diseases of urinary system

802

2752

1.65

34.97

1.2

67.13

63.18

u/l

0.31

560

1836

Iron deficiency anaemia secondary to blood loss (chronic)

159

544

2.97

34.95

1.2

58.29

62.82

u/l

0.30

109

369

Other necrotizing vasculopathies

205

4.41

34.75

1.3

1.2

47.18

52.90

u/l

0.75

147

Monoclonal gammopathy of undetermined significance (MGUS), excluding all cancers (controls excluding all cancers)

111

5.86

34.41

1.2

1.1

56.17

56.12

u/l

0.00

Hypertensive heart and/or renal disease

218

666

2.56

34.38

1.2

55.49

72.78

u/l

1.31

159

425

Follow-up examination after treatment for conditions other than malignant neoplasms

373

1194

2.06

34.24

1.2

59.92

64.12

u/l

0.49

234

822

Multiple myeloma, Monoclonal gammopathy of undetermined significance (MGUS), excluding all cancers (controls excluding all cancers)

212

4.29

34.11

1.3

1.2

58.01

60.07

u/l

0.13

141

Other necrotizing vasculopathies (FG)

141

5.16

33.99

1.3

1.1

45.11

60.07

u/l

2.13

Other diseases of pleura

362

1593

2.03

33.95

1.2

72.08

67.34

u/l

0.14

258

1029

Haemorrhage from respiratory passages

287

1215

2.21

33.89

1.2

67.30

65.73

u/l

0.04

213

787

Diseases of oral cavity, salivary glands and jaws

708

2151

1.70

33.76

1.2

72.35

60.24

u/l

1.23

484

1416

Nephrotic syndrome

6.59

33.56

1.3

1.2

89.55

105.27

u/l

0.15

Secondary uncertain malignant neoplasm, excluding all cancers (controls excluding all cancers)

320

1340

2.12

33.44

1.4

1.2

104.66

57.39

u/l

2.08

219

864

6-mercaptopurine

7.93

33.32

1.3

1.1

58.07

70.21

u/l

0.35

Arthropathies in other diseases classified elsewhere

6.37

33.23

1.4

1.1

46.58

58.31

u/l

1.14

Other disorders of urethra and urinary system

565

2420

1.76

33.22

1.2

64.22

61.45

u/l

0.29

384

1595

Excluding asthma or asthma-COPD overlap

621

1783

1.75

33.03

1.2

63.79

68.93

u/l

0.51

435

1171

Charcot foot

9.85

33.01

1.5

1.2

49.35

63.39

u/l

0.79

Valvular heart disease excluding rheumatic fever

370

1349

2.02

32.95

1.2

80.06

69.59

u/l

0.29

266

875

Hyperlipidaemia, other/unspecified

310

1398

2.12

32.93

1.2

51.57

64.93

u/l

2.46

206

925

Chronic gastritis

249

1094

2.30

32.73

1.2

57.94

64.27

u/l

0.77

163

746

Statin medication

573

1820

1.78

32.68

1.2

67.51

61.73

u/l

0.37

406

1229

Symptoms and signs involving the circulatory and respiratory systems

763

2330

1.65

32.56

1.2

60.46

71.34

u/l

1.80

535

1553

Adalimumab

255

3.88

32.50

1.1

53.68

65.54

u/l

0.86

175

Non-rheumatic valve diseases

367

1340

2.01

32.46

1.2

68.00

69.09

u/l

0.04

264

868

Infection of intervertebral disc (pyogenic)

11.81

32.38

1.2

55.48

44.95

u/l

0.44

Gingivitis and periodontal diseases

696

2144

1.68

32.38

1.2

62.94

60.24

u/l

0.34

486

1409

Chronic tubulo-interstitial nephritis

108

5.74

32.06

1.3

1.2

71.53

58.89

u/l

0.47

Symptoms and signs concerning food and fluid intake

266

3.78

32.06

1.1

1.2

68.67

71.02

u/l

0.06

174

Viral pneumonia

115

342

3.41

32.01

1.3

1.2

65.56

61.40

u/l

0.24

232

Depression medications

166

274

3.06

31.83

1.2

60.66

61.32

u/l

0.03

111

173

Hypo-osmolality and hyponatraemia

161

583

2.79

31.71

1.2

52.08

59.06

u/l

1.07

114

372

Primary_lymphoid and hematopoietic malignant neoplasms

214

893

2.43

31.70

1.2

74.94

69.75

u/l

0.18

163

586

Coagulation defects, purpura and other haemorrhagic conditions

175

666

2.66

31.48

1.3

1.2

68.03

70.20

u/l

0.07

135

445

Paralytic ileus and intestinal obstruction

219

926

2.39

31.44

1.3

1.2

57.10

64.86

u/l

1.04

161

622

Injuries to the hip and thigh

367

1730

1.96

31.25

1.3

1.2

69.11

59.73

u/l

1.27

255

1141

Fungal Sepsis

104

5.78

31.17

1.4

1.2

67.24

56.04

u/l

0.51

Bacterial intestinal infections, IBD co-morbidities

172

653

2.67

31.11

1.2

62.16

62.66

u/l

0.03

126

426

Other pulmonary diagnosis

612

1783

1.73

31.00

1.2

63.69

68.93

u/l

0.52

429

1171

All influenza

200

817

2.47

30.99

1.3

1.1

56.95

66.63

u/l

1.31

138

530

Complications of internal orthopaedic prosthetic devices, implants and grafts

206

855

2.44

30.92

1.3

1.1

54.51

63.84

u/l

1.29

134

549

Depression

728

3113

1.62

30.88

1.2

56.93

64.56

u/l

2.41

502

2107

Unspecified privation

109

321

3.46

30.87

1.2

54.85

60.03

u/l

0.50

215

Other antidepressants

794

2591

1.61

30.87

1.2

62.49

65.43

u/l

0.27

540

1758

ILD differential diagnosis

611

1782

1.72

30.82

1.2

63.51

68.85

u/l

0.53

433

1166

Obesity and other hyperalimentation

475

2650

1.79

30.79

1.2

58.58

62.78

u/l

0.65

324

1775

Cellulitis

187

745

2.54

30.62

1.3

1.2

59.03

64.31

u/l

0.27

136

503

COPD differential diagnosis

610

1783

1.72

30.55

1.2

63.59

68.81

u/l

0.51

432

1167

Obesity

472

2638

1.78

30.49

1.2

58.63

62.64

u/l

0.61

323

1766

Asthma (only as main-diagnosis)

518

1763

1.78

30.47

1.2

57.61

68.89

u/l

2.07

384

1156

Persons encountering health services in other circumstances

286

1369

2.10

30.27

1.2

63.27

66.90

u/l

0.29

162

873

Pleural effusion

144

506

2.89

30.24

1.1

1.2

55.31

61.80

u/l

0.66

106

334

Atrial fibrillation and flutter with reimbursement

232

631

2.38

29.91

1.2

58.50

62.04

u/l

0.20

160

399

Psoriatic and enteropathic arthropathies

114

353

3.28

29.79

1.2

54.42

61.79

u/l

0.67

239

Agranulocytosis

119

379

3.20

29.74

1.2

90.50

58.63

u/l

1.78

257

Lower back pain or/and sciatica

771

3400

1.58

29.74

1.2

55.23

64.52

u/l

3.25

543

2280

Benign neoplasm of colon, rectum, anus and anal canal

490

2532

1.76

29.72

1.2

56.28

62.66

u/l

0.99

322

1685

Ulcerative proctitis

158

4.60

29.72

1.4

1.2

53.29

59.71

u/l

0.63

110

Other gastritis (incl. Duodenitis)

199

828

2.43

29.70

1.2

58.30

65.98

u/l

0.53

136

556

Other/unspecified seropositive rheumatoid arthritis

256

1186

2.18

29.67

1.2

54.25

60.08

u/l

1.14

194

779

Arthropathies

665

2045

1.66

29.46

1.2

61.10

75.20

u/l

2.17

472

1380

Other medical care

308

1494

2.03

29.46

1.3

1.2

85.62

62.76

u/l

1.92

240

969

Collagenous colitis

278

3.60

29.46

1.2

51.66

54.17

u/l

0.21

191

Mood disorders, excluding more controls

730

2783

1.60

29.20

1.2

57.13

63.41

u/l

1.75

497

1878

Spondylopathies

636

2338

1.66

29.20

1.2

55.50

63.56

u/l

2.26

446

1554

Seropositive rheumatoid arthritis, wide

258

1207

2.16

29.18

1.2

54.56

59.75

u/l

0.97

196

795

Cerebrovascular diseases (FINNGEN)

256

830

2.22

29.17

1.2

55.53

64.61

u/l

1.45

177

532

Hypokalaemia

114

358

3.24

29.15

1.2

65.45

61.34

u/l

0.17

228

Benign neoplasm: Colon

419

2273

1.82

28.86

1.2

54.05

63.56

u/l

1.92

277

1508

Covid-19 confirmed case

226

1006

2.27

28.85

1.3

1.2

74.55

65.91

u/l

0.29

188

661

Mood disorders

776

3261

1.57

28.85

1.2

57.71

63.97

u/l

1.80

537

2208

Mood [affective] disorders

774

3258

1.57

28.75

1.2

57.77

63.99

u/l

1.78

535

2205

Implicit fungal Sepsis

5.92

28.68

1.5

1.2

68.86

55.19

u/l

0.63

Sleep disorders (combined)

758

3167

1.58

28.63

1.2

60.16

65.32

u/l

0.91

490

2163

Type 1 diabetes, definitions combined

222

3.87

28.59

1.3

1.2

65.01

79.83

u/l

0.83

155

Other diseases of hard tissues of teeth

475

2013

1.77

28.54

1.2

76.89

60.83

u/l

0.86

322

1322

Other systemic involvement of connective tissue

243

1120

2.19

28.53

1.2

57.23

59.35

u/l

0.13

175

749

Type 1 diabetes, strict (exclude DM2)

223

3.85

28.42

1.3

1.2

65.01

107.28

u/l

1.12

157

Osteoporosis with pathological fracture (FG)

216

3.94

28.34

1.2

1.1

67.34

54.78

u/l

1.07

146

Other/unspecified seropositive rheumatoid arthritis (ICD-10)

249

1163

2.17

28.30

1.2

54.72

60.33

u/l

1.04

188

766

Other disorders of white blood cells

161

4.47

28.18

1.1

1.2

100.86

54.99

u/l

0.48

112

Cystitis

662

2499

1.63

28.16

1.2

64.05

62.15

u/l

0.13

469

1656

Other disorders of glucose regulation and pancreatic internal secretion

227

3.81

27.90

1.3

1.1

57.91

78.49

u/l

0.67

151

Intestinal stricture

255

1209

2.13

27.85

1.3

1.2

58.90

63.88

u/l

0.63

184

779

AV-block

138

446

2.84

27.66

1.2

54.29

70.04

u/l

1.91

101

288

Diabetic neuropathy

126

431

2.97

27.60

1.3

1.2

55.61

61.65

u/l

0.46

278

Artificial opening status

132

4.82

27.44

1.3

1.1

128.71

76.58

u/l

0.35

Enlarged lymph nodes

139

505

2.79

27.43

1.2

91.15

69.48

u/l

0.30

104

340

Cough

330

1651

1.93

27.41

1.2

59.81

71.42

u/l

1.48

226

1068

Parodontitis or operation codes

691

3228

1.58

27.30

1.2

67.58

60.90

u/l

0.43

472

2175

Parodontitis

690

3228

1.58

27.20

1.2

67.58

60.86

u/l

0.43

472

2174

Pain (limb, back, neck, head abdominally)

541

1586

1.72

26.92

1.2

65.97

75.16

u/l

0.59

371

1058

Other diseases of stomach and duodenum

180

4.15

26.82

1.2

52.73

61.27

u/l

0.69

133

Diseases of the eye and adnexa

602

1819

1.66

26.79

1.2

62.94

72.15

u/l

1.09

417

1234

Other CVD (FINNGEN)

103

242

3.40

26.78

1.3

1.2

57.77

62.74

u/l

0.35

149

UC patients in KELA-register (code 208), prior to 1994

139

4.67

26.76

1.4

1.2

67.17

52.76

u/l

1.01

862

3006

1.52

26.63

1.2

61.23

65.44

u/l

0.42

600

2002

Diverticular disease of intestine

544

2163

1.68

26.61

1.2

56.88

63.45

u/l

1.05

360

1471

Peripheral arterial reconstruction

143

536

2.70

26.60

1.2

49.82

64.46

u/l

1.67

347

118

399

3.00

26.60

1.3

1.1

75.87

53.41

u/l

1.31

270

Other disorders of teeth and supporting structures

176

730

2.44

26.50

1.2

72.49

58.98

u/l

0.53

103

462

Sequelae of external causes of morbidity and mortality

216

979

2.23

26.49

1.3

1.2

66.63

65.76

u/l

0.04

161

652

Anxiety disorders, excluding more controls

625

2573

1.62

26.47

1.2

65.91

64.25

u/l

0.14

433

1736

Use of hypnotics and sedatives

801

3028

1.54

26.44

1.2

63.90

63.18

u/l

0.05

546

2042

Acute pancreatitis

163

654

2.52

26.38

1.2

59.16

67.21

u/l

0.86

120

443

Asthma, hospital admissions 3, pneumonia

282

1421

2.00

26.00

1.2

58.53

66.98

u/l

1.11

222

933

Asthma-related pneumonia or sepsis

282

1421

2.00

26.00

1.2

58.53

66.98

u/l

1.11

222

933

Heart failure and coronary heart disease

253

897

2.12

25.91

1.2

48.58

66.07

u/l

4.40

170

583

Chronic periodontitis, including avohilmo

682

3232

1.57

25.89

1.2

67.99

60.83

u/l

0.46

464

2179

Asthma-related pneumonia

281

1417

2.00

25.86

1.2

58.56

67.04

u/l

1.11

221

930

Decubitus ulcer and pressure area

147

4.46

25.81

1.3

1.2

59.06

54.99

u/l

0.22

Gastroduodenal ulcer

205

917

2.25

25.76

1.2

60.46

64.26

u/l

0.31

136

615

Obesity due to excess calories

345

1868

1.86

25.73

1.2

58.04

62.34

u/l

0.48

231

1246

Purpura and other haemorrhagic conditions

122

431

2.87

25.45

1.3

1.2

77.30

69.16

u/l

0.21

286

Immunodeficiencies

137

4.57

25.33

1.3

1.2

133.71

62.75

u/l

0.48

Care involving use of rehabilitation procedures

454

2534

1.71

25.31

1.2

73.87

64.34

u/l

0.46

367

1660

Senile cataract

506

1862

1.70

25.28

1.3

1.2

57.70

62.82

u/l

0.65

359

1239

Headache

438

2119

1.74

25.28

1.2

56.09

65.21

u/l

2.25

313

1414

Disorders of the thyroid gland

701

2955

1.56

25.23

1.2

61.41

62.75

u/l

0.16

472

1988

Amputation of ankle bones

7.66

25.21

1.4

1.2

49.09

50.03

u/l

0.05

Secondary malignant neoplasm of other and unspecified sites, excluding all cancers (controls excluding all cancers)

176

750

2.37

24.99

1.5

1.2

140.61

56.94

u/l

2.21

127

476

Osteonecrosis

173

4.09

24.84

1.3

1.2

73.41

55.31

u/l

0.66

126

Asthma, hospital admission 2, infections

432

2484

1.72

24.76

1.2

57.04

68.49

u/l

2.60

336

1651

Asthma-related infections

432

2484

1.72

24.76

1.2

57.04

68.49

u/l

2.60

336

1651

Total colectomy

128

4.67

24.65

1.6

1.2

57.41

59.33

u/l

0.07

Total colectomy operation

128

4.67

24.65

1.6

1.2

57.41

59.33

u/l

0.07

Other or unspecified ileus, impaction or obstruction

151

605

2.52

24.52

1.4

1.2

59.17

64.51

u/l

0.47

111

401

Dorsalgia

730

2569

1.54

24.47

1.2

56.68

66.07

u/l

2.83

522

1722

Other reaction to severe stress, and adjustment disorders

278

1427

1.96

24.43

1.3

1.2

70.81

60.14

u/l

0.90

207

970

Irritable bowel syndrome

222

1052

2.13

24.35

1.1

1.2

57.46

60.99

u/l

0.41

143

701

Parodontitis and operation codes

644

3219

1.56

24.29

1.2

60.65

62.50

u/l

0.19

437

2169

Exclusions for E4_PCOS_BROAD

143

562

2.57

24.19

1.2

66.14

80.96

u/l

0.62

110

386

Syncope and collapse

309

1451

1.90

24.15

1.2

60.07

63.85

u/l

0.29

213

935

Presence of cardiac and vascular implants and grafts

326

1320

1.88

24.07

1.2

56.92

66.64

u/l

0.74

214

878

Other infectious diseases

237

3.53

24.03

1.2

68.72

67.85

u/l

0.01

159

Psoriasis

239

1171

2.06

24.01

1.2

58.42

65.90

u/l

0.87

171

778

Presence of other functional implants

433

1782

1.73

24.00

1.2

56.14

64.48

u/l

1.28

274

1202

Hydronephrosis

291

3.24

23.98

1.2

76.17

59.10

u/l

0.76

199

Methotrexate

132

502

2.66

23.92

1.1

60.31

62.29

u/l

0.10

106

330

Persons encountering health services for specific procedures, not carried out

178

3.94

23.83

1.3

1.2

62.98

53.32

u/l

0.68

124

L04AC Interleukin inhibitors

141

4.36

23.54

1.2

49.57

58.08

u/l

0.58

Other disorders of skin and subcutaneous tissue, not elsewhere classified

126

472

2.70

23.54

1.2

56.85

59.12

u/l

0.15

321

Elevated blood glucose level

212

3.65

23.48

1.1

1.2

57.20

58.86

u/l

0.09

146

Benign neoplasm of other and ill-defined parts of digestive system

164

700

2.37

23.30

1.2

54.43

58.81

u/l

0.58

126

463

Viral pneumonia (unknown virus, not influenza)

168

4.00

23.25

1.3

1.2

70.89

62.05

u/l

0.42

119

Neurotic, stress-related and somatoform disorders

649

2994

1.55

23.15

1.2

66.47

65.22

u/l

0.10

451

2030

Depression or dysthymia

538

1848

1.64

23.12

1.2

60.27

65.64

u/l

0.52

367

1243

Sequelae with surgical and medical care as external cause

172

752

2.31

23.10

1.3

1.2

63.98

64.47

u/l

0.02

125

493

Abnormal findings on diagnostic imaging of lung

358

1972

1.78

23.09

1.2

55.78

63.32

u/l

0.97

229

1314

Other cataract

345

1479

1.82

23.00

1.3

1.2

65.95

64.67

u/l

0.07

234

968

Gout due to impairment of renal function

11.16

22.94

1.3

1.1

73.62

53.88

u/l

0.48

Hepatic failure, not elsewhere classified

100

5.05

22.88

1.3

1.2

58.70

51.28

u/l

0.37

Fracture of lumbar spine and pelvis

174

767

2.29

22.82

1.2

64.95

60.48

u/l

0.41

126

497

Anxiety disorders

654

3024

1.54

22.77

1.2

66.18

65.26

u/l

0.07

456

2051

Recurrent or chronic depression

311

1202

1.88

22.77

1.2

59.84

63.84

u/l

0.51

207

818

Diaphragmatic hernia

299

1614

1.87

22.64

1.2

55.62

61.18

u/l

0.86

200

1076

Other CVD

151

629

2.43

22.61

1.3

1.2

55.84

62.35

u/l

0.69

105

407

Spondylopathies (FG)

112

403

2.81

22.60

1.2

50.70

60.98

u/l

1.14

271

Mycoses

212

1018

2.10

22.53

1.3

1.2

68.06

63.86

u/l

0.26

154

672

Acute bronchitis

303

1611

1.85

22.45

1.2

70.57

65.82

u/l

0.24

221

1076

Hypothyroidism, other/unspecified

651

2804

1.54

22.38

1.2

60.04

61.22

u/l

0.15

439

1879

Benign neoplasm: Colon, unspecified

174

771

2.27

22.33

1.2

51.20

55.61

u/l

0.63

116

492

Weight loss

294

3.15

22.32

1.1

1.2

60.44

67.13

u/l

0.26

205

Vitamin B12 deficiency anaemia

325

3.03

22.31

1.3

1.1

53.43

58.34

u/l

0.48

222

Other diseases of arteries and capillaries

284

3.19

22.29

1.2

57.53

57.50

u/l

0.00

195

Pyogenic arthritis

169

3.91

22.24

1.3

1.1

58.72

60.87

u/l

0.09

110

Papulosquamous disorders

308

1689

1.84

22.17

1.2

57.40

63.68

u/l

0.98

218

1114

Conduction disorders

211

835

2.12

22.12

1.2

59.20

75.99

u/l

1.34

151

521

Malignant neoplasm of breast, ER-negative, excluding all cancers (controls excluding all cancers)

201

913

2.14

22.11

1.2

56.01

58.15

u/l

0.30

134

608

Other disorders involving the immune mechanism, not elsewhere classified

5.28

22.07

1.2

59.69

61.05

u/l

0.05

Benign neoplasms

682

2502

1.53

21.95

1.2

62.68

67.90

u/l

0.59

465

1709

Other special examinations and investigations of persons without complaint or reported diagnosis

463

1394

1.69

21.90

1.2

61.36

71.03

u/l

0.91

299

967

Endocarditis

5.53

21.75

1.3

1.2

46.91

63.36

u/l

1.32

Postprocedural disorders of digestive system, not elsewhere classified

5.01

21.68

1.6

1.2

54.59

51.82

u/l

0.16

Other respiratory diseases principally affecting the interstitium

143

593

2.44

21.68

1.1

1.2

57.79

63.11

u/l

0.48

112

386

Falls/tendency to fall

795

2697

1.48

21.61

1.2

66.24

66.84

u/l

0.05

531

1837

Other joint disorders

599

2043

1.57

21.42

1.2

57.51

75.17

u/l

3.31

409

1379

Injuries to the abdomen, lower back, lumbar spine and pelvis

281

1503

1.87

21.41

1.2

79.57

63.33

u/l

0.49

207

984

Idiopathic gout

236

3.36

21.31

1.2

58.49

60.00

u/l

0.06

157

Other acute lower respiratory infections

369

2054

1.72

21.31

1.2

67.22

67.44

u/l

0.01

269

1377

Bronchitis

761

3402

1.47

21.20

1.2

62.06

64.49

u/l

0.20

547

2280

Open wound of ankle and foot

293

3.08

21.14

1.3

1.2

63.07

63.28

u/l

0.01

198

Abnormal weight loss

263

3.21

21.06

1.1

1.2

61.94

64.90

u/l

0.09

181

Hypothyreosis and Thyroxine purchase for inclusion criteria

674

2965

1.51

21.02

1.2

59.48

61.44

u/l

0.30

457

1984

Volume depletion

243

3.30

21.01

1.3

1.1

75.21

64.43

u/l

0.44

147

Kela reimbursement Agammaglobulinemia (D80-84)

11.79

20.89

1.5

1.2

245.47

89.08

u/l

0.36

Symptoms and signs involving the urinary system

552

2744

1.56

20.89

1.2

67.52

63.67

u/l

0.30

350

1852

Acute pancreatitis (for exclusion)

163

728

2.26

20.85

1.2

59.16

62.21

u/l

0.28

120

477

Exposure to other specified factors

510

3047

1.58

20.71

1.2

61.18

66.22

u/l

0.65

321

2082

Soft tissue disorders

721

2516

1.49

20.62

1.2

62.75

70.42

u/l

1.05

494

1711

Viral and other specified intestinal infections

131

521

2.47

20.51

1.3

1.2

81.79

76.55

u/l

0.09

106

353

Injuries to the head

773

3466

1.46

20.47

1.2

65.66

66.74

u/l

0.09

519

2365

Developmental endpoint to exclude non autoimmune-cases from E4_HYTHY_AI_STRICT

264

1418

1.88

20.37

1.2

67.79

63.07

u/l

0.39

194

940

Thrombocytopenia, unspecified

204

3.50

20.32

1.3

1.2

82.93

57.66

u/l

0.56

140

Diseases of the respiratory system

493

1524

1.63

20.32

1.2

63.01

69.22

u/l

0.57

338

999

Diseases of the musculoskeletal system and connective tissue

350

985

1.79

20.30

1.2

70.73

78.96

u/l

0.41

245

657

Immunodeficiency with predominantly antibody defects

5.45

20.28

1.3

1.2

162.61

66.86

u/l

0.43

Gastric ulcer

138

582

2.39

20.17

1.2

1.1

61.20

66.61

u/l

0.35

390

Failure and rejection of transplanted organs and tissues

7.67

20.15

1.2

85.30

121.14

u/l

0.18

Hard cardiovascular diseases

583

2439

1.54

20.12

1.2

55.00

64.51

u/l

2.81

401

1634

Hepatocellular carcinoma, excluding all cancers (controls excluding all cancers)

6.72

20.11

1.0

1.1

56.25

51.82

u/l

0.15

Obesity, other/unspecified

252

1340

1.89

20.05

1.2

59.58

59.79

u/l

0.02

183

887

General examination and investigation of persons without complaint and reported diagnosis

435

1393

1.67

20.05

1.2

65.03

71.06

u/l

0.54

283

966

Disorder of lipoprotein metabolism, unspecified

112

431

2.63

19.92

1.2

46.22

62.90

u/l

2.88

275

Sleep apnoea, including avohilmo

707

3122

1.48

19.90

1.2

60.00

63.05

u/l

0.47

447

2131

Other pleural conditions

305

2.96

19.74

1.2

53.10

60.11

u/l

0.54

204

Invasive ventilation

208

3.43

19.73

1.2

72.80

60.51

u/l

0.48

144

ILD, hospital admission 2, with pulmonary infections

259

3.13

19.59

1.1

1.2

56.69

68.62

u/l

0.84

167

IgA nephropathy (IgA glomerulonephritis)

5.83

19.59

1.2

62.39

54.28

u/l

0.36

Sleep apnoea

670

3077

1.48

19.51

1.2

60.15

63.03

u/l

0.42

423

2096

Bacterial pneumoniae

283

1385

1.82

19.50

1.3

1.2

58.67

64.28

u/l

0.61

247

877

Malignant neoplasm of breast, HER-negative

182

873

2.11

19.46

1.2

57.15

58.11

u/l

0.13

123

597

Cardiodefibrillation

264

1439

1.85

19.36

1.2

54.21

66.80

u/l

1.76

200

917

Nerve, nerve root and plexus disorders

756

3288

1.45

19.36

1.2

56.79

63.40

u/l

1.91

510

2217

Asthma (diagnoses ohter than nonallergic)

609

3498

1.49

19.17

1.2

56.33

65.26

u/l

2.52

448

2334

Other and unspecified disorders of white blood cells

120

4.28

19.17

1.1

1.2

58.06

53.13

u/l

0.29

All influenza (not pneumonia)

109

422

2.61

19.13

1.3

1.1

62.27

67.76

u/l

0.33

284

Seronegative rheumatoid arthritis

104

394

2.67

19.11

1.2

1.1

53.62

63.07

u/l

0.90

259

Hypoglycaemia, other or unspecified

188

3.52

19.10

1.3

1.2

54.67

83.73

u/l

0.88

130

Anxiety (asthma-related co-morbidities)

407

1964

1.64

19.06

1.2

64.55

66.77

u/l

0.16

285

1334

ILD, hospital admissions 3, with pneumonia sepsis

213

3.34

19.00

1.1

1.2

55.24

64.45

u/l

0.55

139

Chronic ulcer of skin, not elsewhere classified

189

3.50

18.95

1.2

56.43

57.41

u/l

0.04

131

Vocal cord dysfunction

318

2.80

18.86

1.2

59.26

69.03

u/l

0.86

204

Chronic hepatitis NAS

7.68

18.84

1.3

1.1

47.20

50.36

u/l

0.17

Other (not insulin) diabetes medications

683

2808

1.47

18.79

1.2

57.40

64.13

u/l

1.46

455

1888

Thyrotoxicosis, other and/or unspecified

164

767

2.16

18.78

1.2

77.79

63.36

u/l

0.91

109

520

Genitourinary diseases

377

1110

1.71

18.75

1.2

76.55

77.59

u/l

0.03

265

755

Calcific aortic valvular stenosis, including rheumatic fever

206

1029

1.97

18.47

1.2

53.46

63.60

u/l

1.42

152

671

Other external causes of accidental injury

606

2011

1.51

18.46

1.2

66.52

69.13

u/l

0.22

410

1375

Myocardial infarction

365

1567

1.68

18.44

1.2

54.70

62.53

u/l

1.37

237

1029

Glucagon-like peptide-1 (GLP-1) analogues

414

2118

1.62

18.38

1.2

56.48

63.05

u/l

0.97

248

1427

Operations 2 for CAVS

205

1025

1.97

18.38

1.2

53.71

63.64

u/l

1.36

151

667

Calcific aortic valvular stenosis, diagnosis (helper)

205

1025

1.97

18.38

1.2

53.71

63.64

u/l

1.36

151

667

Other and unspecified disorders involving the immune mechanism, not elsewhere classified

4.97

18.37

1.2

63.03

61.24

u/l

0.06

Any mental disorder

809

2847

1.43

18.29

1.2

60.67

66.56

u/l

0.88

545

1922

Calcific aortic valvular stenosis, operated

205

1027

1.97

18.28

1.2

53.71

64.11

u/l

1.45

151

669

Calcific aortic valvular stenosis

205

1027

1.97

18.28

1.2

53.71

64.11

u/l

1.45

151

669

307

1770

1.73

18.18

1.2

57.11

71.32

u/l

2.42

241

1167

Gingival hyperplasia

4.89

18.09

1.4

1.2

145.74

70.47

u/l

0.50

Disorders of vitreous body and globe

386

2326

1.63

18.09

1.3

1.2

61.27

61.10

u/l

0.01

260

1534

Hypertensive Heart Disease

163

622

2.16

18.06

1.2

52.03

73.55

u/l

1.68

115

397

Disorders of vitreous body

378

2276

1.64

18.05

1.2

61.55

61.39

u/l

0.01

256

1502

Chronic lower respiratory diseases

849

3273

1.41

18.03

1.2

58.55

69.68

u/l

2.93

603

2200

Intestinal malabsorption

139

3.90

18.03

1.4

1.2

56.24

62.78

u/l

0.30

101

Vertebral, anorectal, cardiavascular, thracheoesophagial, renal and limb anomaly

121

489

2.42

18.01

1.3

1.2

121.46

82.50

u/l

0.45

343

Postmenopausal osteoporosis with pathological fracture

191

3.43

17.99

1.2

72.17

54.61

u/l

1.22

127

Myocardial infarction, without ST-elevation

277

1443

1.78

17.98

1.2

52.63

62.00

u/l

2.11

186

928

Bacterial pneumonia, not elsewhere classified

265

1306

1.81

17.88

1.3

1.2

57.07

64.12

u/l

0.90

233

820

Type 1 diabetes, strict definition, subgroup 1

139

3.84

17.87

1.3

1.2

65.12

93.43

u/l

1.20

Intracranial trauma

391

1796

1.63

17.86

1.2

64.78

73.66

u/l

0.89

278

1225

Neurological diseases, wide definition

173

396

2.20

17.86

1.2

64.34

95.85

u/l

1.02

128

255

Cardiomyopathy

122

516

2.39

17.77

1.2

82.94

70.74

u/l

0.18

333

Persons encountering health services for examination and investigation

446

1394

1.61

17.71

1.2

61.08

71.03

u/l

0.98

296

967

Hypotension

120

505

2.40

17.69

1.3

1.2

56.58

62.02

u/l

0.44

333

Type 2 diabetes, definitions combined

657

2686

1.46

17.66

1.2

58.89

63.70

u/l

0.81

438

1797

In situ neoplasms

232

1192

1.87

17.66

1.2

62.46

56.65

u/l

0.53

167

777

Parodontitis, under 40 years

159

3.62

17.65

1.3

66.51

56.66

u/l

0.74

105

Benign neoplasm: Sigmoid colon

128

555

2.33

17.64

1.3

1.2

55.30

58.26

u/l

0.18

347

Malignant neoplasm of intrahepatic ducts, biliary tract and gallbladder, excluding all cancers (controls excluding all cancers)

141

3.82

17.63

1.1

1.2

52.55

54.01

u/l

0.07

Vascular disorders of the intestines

179

3.46

17.55

1.3

1.2

54.89

61.81

u/l

0.38

126

Other disorders of gingiva or/and edentulous alveolar ridge

124

4.03

17.49

1.3

1.2

133.54

69.21

u/l

0.51

Parodontitis, under 40 years, or operation codes

160

3.59

17.49

1.3

66.51

57.42

u/l

0.66

106

Thyrotoxicosis

204

1063

1.94

17.38

1.1

1.2

73.71

61.60

u/l

1.00

141

706

Acute upper respiratory infections of multiple and unspecified sites

506

2493

1.53

17.33

1.2

63.20

66.89

u/l

0.23

371

1671

Isolated proteinuria with specified morphological lesion

8.90

17.29

1.1

1.2

112.53

49.71

u/l

0.67

Unspecified haematuria

284

1396

1.75

17.24

1.2

65.44

67.17

u/l

0.09

188

921

Malignant neoplasm of prostate, excluding all cancers (controls excluding all cancers)

178

512

2.10

17.13

1.5

1.2

96.95

55.01

u/l

1.96

128

315

Ulcerative enterocolitis

4.66

17.13

1.2

55.52

55.34

u/l

0.01

All anxiety disorders

410

2081

1.59

17.13

1.2

64.56

64.38

u/l

0.01

287

1420

Hypoparathyroidism

109

4.24

17.09

1.3

1.2

69.49

56.30

u/l

0.39

Cardiomyopathy, other and unspecified

202

3.26

17.08

1.2

1.1

67.06

64.34

u/l

0.05

134

Accidents

597

2011

1.49

16.99

1.2

64.95

69.13

u/l

0.40

405

1375

Candidiasis

109

448

2.46

16.97

1.3

1.2

61.58

58.72

u/l

0.15

307

Enteropathic arthropathies

5.49

16.94

1.2

1.1

44.54

58.26

u/l

1.14

Type 1 diabetes, strict definition

159

3.55

16.84

1.3

1.2

63.70

90.39

u/l

1.25

107

Type 2 diabetes, definitions combined, including avohilmo

656

2687

1.45

16.76

1.2

58.48

64.20

u/l

1.04

435

1804

Psychiatric diseases

783

2785

1.41

16.75

1.2

60.85

66.75

u/l

0.85

527

1874

Diseases of pulp and periapical tissues, including avohilmo

751

2756

1.42

16.69

1.2

64.01

65.71

u/l

0.16

502

1860

Type 2 diabetes, strict (exclude DM1)

657

2719

1.45

16.65

1.2

58.98

64.50

u/l

0.98

438

1820

Drug-induced neutropenia

242

3.03

16.64

1.2

80.09

56.16

u/l

1.30

171

Symptoms and signs involving the skin and subcutaneous tissue

480

3168

1.51

16.53

1.2

57.94

64.00

u/l

1.04

345

2096

Symptoms and signs involving cognition, perception, emotional state and behaviour

674

3314

1.43

16.49

1.2

57.90

65.76

u/l

1.27

460

2234

Lymphoid leukaemia

134

3.80

16.49

1.1

67.58

90.67

u/l

0.41

Sicca syndrome [Sjögren]

326

2.71

16.45

1.3

1.1

55.33

55.45

u/l

0.01

233

Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified

684

3128

1.43

16.43

1.2

65.71

61.13

u/l

0.28

470

2097

Fibrosis of liver

12.19

16.40

1.3

56.08

49.60

u/l

—

Gonarthrosis [arthrosis of knee](FG)

519

2026

1.51

16.38

1.1

1.2

59.49

64.28

u/l

0.61

330

1369

Thyroiditis, ILD-related definition

349

2.64

16.38

1.2

55.65

58.66

u/l

0.23

237

Colectomy operation

134

612

2.21

16.37

1.3

1.2

68.33

58.63

u/l

0.53

412

Dental caries 1 and operation codes

610

2134

1.47

16.32

1.2

70.43

64.52

u/l

0.50

400

1445

Diagnoses used for exclusion with ILD

192

1002

1.93

16.31

1.2

52.58

65.05

u/l

2.08

146

658

malignant neoplasm of male genital organs, excluding all cancers (controls excluding all cancers)

179

537

2.05

16.28

1.5

1.2

97.72

54.68

u/l

2.04

128

326

Other and unspecified local infections of skin and subcutaneous tissue

267

2.88

16.20

1.3

1.1

57.53

66.73

u/l

0.31

187

Alcohol use disorder, Swedish definition

361

2090

1.61

16.19

1.2

62.44

63.10

u/l

0.04

231

1424

Bacterial pneumonia (organism specified)

304

1655

1.68

16.10

1.3

1.2

59.07

66.17

u/l

0.79

264

1049

External causes of morbidity and mortality

479

1558

1.55

16.10

1.2

59.78

70.35

u/l

1.28

321

1070

malignant neoplasm of male genital organs

242

844

1.83

16.08

1.4

1.2

105.24

57.07

u/l

1.62

178

528

Other local infections of skin and subcutaneous tissue

296

2.77

16.04

1.3

1.1

56.91

71.43

u/l

0.59

201

Malignant neoplasm of digestive organs, excluding all cancers (controls excluding all cancers)

279

1263

1.73

16.04

1.1

1.2

66.50

57.41

u/l

0.59

205

815

Ischemic heart diseases

569

2426

1.47

16.03

1.2

56.27

64.07

u/l

2.02

406

1613

Dental pulpitis 4

748

2765

1.41

15.98

1.2

64.00

65.72

u/l

0.16

502

1866

SLE (Finngen)

4.78

15.93

1.2

1.0

40.28

52.10

u/l

0.94

Giant cell arteritis

115

4.01

15.91

1.2

46.83

54.52

u/l

0.94

Disorders of synovium and tendon

372

2112

1.59

15.90

1.2

59.85

62.33

u/l

0.32

260

1414

Codes for special purposes

297

1777

1.68

15.89

1.3

1.2

70.24

64.17

u/l

0.26

245

1152

Viral hepatitis, IBD co-morbidity

4.73

15.88

1.3

1.1

70.79

46.07

u/l

2.12

Other dorsopathies, not elsewhere classified

695

2580

1.43

15.87

1.2

56.42

66.03

u/l

2.89

482

1732

Dental pulpitis 1

747

2766

1.41

15.83

1.2

63.89

65.75

u/l

0.17

501

1867

Sarcoidosis

111

477

2.35

15.70

1.2

55.44

59.28

u/l

0.30

322

Trigger finger

127

578

2.22

15.68

1.3

1.2

52.70

62.01

u/l

1.30

387

Non-Hodgkin lymphoma, all, excluding all cancers (controls excluding all cancers)

393

2.50

15.61

1.2

1.1

58.81

59.13

u/l

0.02

256

Ischaemic heart disease, wide definition

562

2404

1.47

15.55

1.2

55.56

64.03

u/l

2.31

396

1605

Benign neoplasm: Descending colon

169

3.37

15.48

1.3

1.2

58.71

55.40

u/l

0.16

110

Seropositive rheumatoid arthritis, strict definition

130

601

2.19

15.45

1.2

58.04

62.13

u/l

0.38

105

405

Unspecified jaundice

131

3.73

15.45

1.2

53.51

61.42

u/l

0.46

Other metabolic disorders

108

462

2.36

15.44

1.2

76.76

55.28

u/l

1.57

303

Provisional assignment of new diseases of uncertain etiology

295

1776

1.67

15.44

1.3

1.2

69.96

64.26

u/l

0.24

243

1152

ILD, hospital admissions

112

487

2.33

15.42

1.1

1.2

56.77

63.77

u/l

0.60

323

Other specified/unspecified systemic involvement of connective tissue

200

3.16

15.40

1.2

44.24

53.09

u/l

1.05

141

Chronic myeloproliferative disease

7.30

15.40

1.2

49.82

42.43

u/l

0.38

Other diseases of anus and rectum

208

1134

1.84

15.40

1.3

1.2

53.28

65.16

u/l

2.27

138

767

Other arrhythmias

425

2119

1.54

15.37

1.2

68.75

64.42

u/l

0.15

304

1386

Retention of urine

213

983

1.84

15.31

1.2

70.34

68.55

u/l

0.06

153

638

Episodal and paroxysmal disorders

777

2874

1.39

15.28

1.2

59.14

70.43

u/l

2.32

505

1980

Malignant neoplasm of prostate

235

821

1.82

15.26

1.4

1.2

106.54

56.44

u/l

1.66

174

509

Isolated proteinuria

4.73

15.25

1.2

89.09

59.71

u/l

0.78

Congenital malformations, deformations and chromosomal abnormalities

383

2357

1.56

15.23

1.3

1.2

62.95

67.47

u/l

0.57

265

1598

Other (seronegative) rheumatoid arthritis, wide

159

798

2.01

15.20

1.2

53.02

61.23

u/l

1.29

118

529

Open wound of lower leg

106

453

2.36

15.18

1.3

1.2

101.05

59.71

u/l

0.45

309

Other interstitial pulmonary diseases

112

491

2.31

15.14

1.1

1.2

56.77

63.75

u/l

0.60

323

373

2188

1.57

15.12

1.2

63.26

63.33

u/l

0.00

241

1495

Injuries to the thorax

295

1789

1.66

15.03

1.2

71.65

60.34

u/l

1.20

207

1187

Myocardial infarction, strict

326

1461

1.64

15.03

1.2

53.78

62.36

u/l

1.37

210

949

Interstitial lung disease

112

493

2.30

15.00

1.1

1.2

56.77

63.53

u/l

0.57

326

Interstitial lung disease endpoints

112

493

2.30

15.00

1.1

1.2

56.77

63.53

u/l

0.57

326

Dental caries, including avohilmo

546

1896

1.48

14.95

1.2

69.53

64.50

u/l

0.39

363

1279

Dental caries 1

546

1896

1.48

14.94

1.2

69.53

64.50

u/l

0.39

363

1279

Eosinophilic disease (BM)

7.75

14.92

1.2

43.36

54.61

u/l

0.71

Acute upper respiratory infections

727

3286

1.39

14.92

1.2

60.06

64.65

u/l

0.44

508

2206

STROKE

402

1800

1.56

14.91

1.2

55.68

64.94

u/l

2.38

277

1180

Non-selective monoamine reuptake inhibitors

294

1732

1.66

14.85

1.1

1.2

54.76

62.52

u/l

1.76

203

1142

Asthma, including avohilmo

803

3417

1.37

14.83

1.2

57.47

69.22

u/l

3.34

581

2292

Acquired absence of limb

9.47

14.79

1.2

1.1

55.40

61.73

u/l

—

L02BA Anti-estrogens

151

753

2.03

14.73

1.2

59.31

60.51

u/l

0.11

113

501

Psoriasis vulgaris

142

692

2.07

14.72

1.2

55.08

63.03

u/l

0.86

467

390

2268

1.55

14.68

1.2

63.71

65.12

u/l

0.08

253

1547

Fracture of rib(s), sternum and thoracic spine

198

1083

1.84

14.59

1.2

74.13

60.00

u/l

1.14

135

696

ILD, hospital admissions 1, main diag only

103

443

2.35

14.58

1.1

1.2

58.66

61.41

u/l

0.18

294

Disorders of sclera, cornea, iris and ciliary body

366

2358

1.56

14.52

1.2

54.20

63.86

u/l

2.55

276

1563

Persons with potential health hazards related to communicable diseases

235

1345

1.74

14.40

1.3

1.2

76.21

69.39

u/l

0.21

185

913

Early onset COPD, excluding more controls

141

691

2.05

14.36

1.1

1.2

54.57

64.07

u/l

1.02

441

Degeneration of macula and posterior pole

317

1623

1.62

14.32

1.2

57.51

63.53

u/l

0.63

197

1075

Dental caries 3

577

2044

1.45

14.29

1.2

69.65

67.67

u/l

0.12

374

1393

Lymphoid leukaemia

148

3.44

14.28

1.1

67.58

86.33

u/l

0.35

104

Mixed connective tissue disease

220

2.96

14.27

1.2

49.35

53.93

u/l

0.28

152

Coronary atherosclerosis

479

2085

1.49

14.24

1.2

56.05

63.40

u/l

1.61

331

1373

Parodontitis, under 40 years and operation codes

148

3.41

14.22

1.3

69.56

57.16

u/l

0.89

Parodontitis, operation under 40 years and operation codes

148

3.41

14.22

1.3

69.56

57.16

u/l

0.89

Missing teeth due to accident, extraction or parodontitis

381

2.44

14.18

1.2

61.05

60.67

u/l

0.02

245

Other anxiety disorders

286

1543

1.65

14.16

1.2

66.85

63.57

u/l

0.19

202

1068

Dental caries 3 and operation codes

625

2260

1.42

14.15

1.2

69.18

67.53

u/l

0.11

405

1542

Concussion

317

1711

1.61

14.14

1.2

61.71

74.50

u/l

1.54

226

1161

Psoriatic arthropathies

334

2.54

14.12

1.2

58.81

68.58

u/l

0.68

215

Tubulo-interstitial nephritis, not specified as acute or chronic

179

3.17

14.12

1.3

1.1

61.15

57.83

u/l

0.12

122

Ankylosing spondylitis, ICD10

271

2.73

14.09

1.1

1.2

52.19

64.04

u/l

0.88

188

Myelodysplastic syndrome, excluding all cancers (controls excluding all cancers)

5.12

13.90

1.1

49.13

54.50

u/l

0.25

Major coronary heart disease event

487

2218

1.47

13.79

1.2

53.63

62.54

u/l

2.51

344

1467

Disorders of continuity of bone

297

2.62

13.79

1.2

1.1

67.74

54.77

u/l

0.96

210

Viral infections characterized by skin and mucous membrane lesions

278

1700

1.64

13.73

1.2

65.22

67.66

u/l

0.17

197

1134

Pacemaker

214

1185

1.77

13.73

1.2

60.10

67.69

u/l

0.43

157

762

Misadventures to patients during surgical and medical care

106

474

2.26

13.72

1.3

1.1

50.30

59.77

u/l

1.02

323

Cholecystitis

430

2.32

13.71

1.3

1.2

58.02

62.33

u/l

0.32

292

Hypothyroidism, strict autoimmune, 3 medication purchases required

585

2824

1.42

13.69

1.2

56.73

62.08

u/l

1.24

384

1890

Carbimazole or st.post thyroidectomy, condition for graves disease

161

843

1.93

13.66

1.1

1.2

77.29

58.03

u/l

1.89

111

572

Pruritus

352

2.47

13.62

1.2

53.87

63.58

u/l

0.73

233

Type1 diabetes, definitions combined, early onset

147

3.36

13.59

1.3

1.2

68.03

123.66

u/l

0.92

100

Temporal arteritis

101

3.95

13.58

1.2

46.28

55.05

u/l

0.95

Non-follicular lymphoma, hilmo, excluding all cancers

254

2.75

13.55

1.2

57.51

58.34

u/l

0.04

165

Personality disorders, excluding more controls

163

859

1.91

13.52

1.1

1.2

56.98

59.14

u/l

0.19

117

588

Other diseases of pericardium

106

3.84

13.46

1.3

1.2

43.29

62.29

u/l

2.40

Benign neoplasm: Transverse colon

278

2.66

13.43

1.2

1.1

52.88

59.01

u/l

0.45

180

Valvular operations

397

2.36

13.40

1.3

1.2

90.79

72.93

u/l

0.16

263

Paroxysmal tachycardia

146

623

1.99

13.35

1.3

1.2

68.19

63.80

u/l

0.15

111

393

Paralytic ileus

3.95

13.29

1.1

1.2

53.75

50.87

u/l

0.19

Substance abuse, excluding more controls

352

1999

1.55

13.29

1.2

62.77

65.92

u/l

0.18

225

1339

Dorsopathies

699

2592

1.38

13.29

1.2

60.88

66.56

u/l

1.09

482

1742

Postprocedural endocrine and metabolic disorders, not elsewhere classified

430

2.30

13.29

1.2

69.52

55.08

u/l

0.96

285

Chronic lymphocytic leukaemia, helper endpoint

5.21

13.21

1.1

1.2

65.28

53.39

u/l

0.44

Chronic lymphocytic leukaemia and small lyphocytis leukaemia, excluding all cancers (controls excluding all cancers)

5.21

13.21

1.1

1.2

65.28

53.39

u/l

0.44

Disorders of skin appendages

311

1974

1.58

13.20

1.2

69.12

64.51

u/l

0.29

210

1317

Urticaria and erythema

253

1528

1.66

13.19

1.2

72.78

65.32

u/l

0.16

176

1011

Arthropathic psoriasis

396

2.35

13.06

1.2

57.18

56.29

u/l

0.07

272

Intestinal adhesions without obstruction

243

2.75

12.98

1.2

1.1

47.21

58.70

u/l

1.30

171

Benign neoplasm: Pancreas

4.96

12.92

1.3

1.2

62.39

47.26

u/l

0.96

Acute myeloid leukaemia and myelodysplastic syndromes, excluding all cancers (controls excluding all cancers)

4.41

12.91

1.1

1.2

51.78

55.58

u/l

0.19

Injuries to the knee and lower leg

798

3417

1.34

12.90

1.2

64.53

66.20

u/l

0.09

556

2306

Lichen simplex chronicus and prurigo

195

2.97

12.85

1.2

49.46

60.61

u/l

1.13

132

Benign neoplasm: Colon, unspecified

174

954

1.84

12.82

1.2

51.20

64.97

u/l

2.64

116

629

Other disorders of adrenal gland

129

3.48

12.80

1.2

81.89

85.77

u/l

0.05

Open wound of head

326

2075

1.55

12.79

1.2

59.38

67.15

u/l

1.04

201

1389

Major coronary heart disease event excluding revascularizations

439

2062

1.48

12.77

1.2

54.62

61.87

u/l

1.47

299

1371

Pulmonary heart disease, diseases of pulmonary circulation

217

1271

1.72

12.72

1.2

60.28

63.45

u/l

0.22

159

833

Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure

292

2.57

12.69

1.2

70.60

67.63

u/l

0.07

203

COPD (mode)

197

882

1.78

12.68

1.2

50.68

69.20

u/l

2.13

131

567

Vascular diseases of the intestine

102

3.80

12.58

1.3

1.2

56.93

50.25

u/l

0.36

Benign neoplasm: Rectum, anus and anal canal

125

618

2.04

12.54

1.2

58.73

57.49

u/l

0.05

391

Other diseases of blood and blood-forming organs

198

2.92

12.51

1.2

64.81

51.72

u/l

0.76

136

Myocarditis

107

3.69

12.48

1.3

1.1

67.27

60.06

u/l

0.21

Acute posthaemorrhagic anaemia

4.08

12.42

1.7

1.1

70.35

53.03

u/l

0.96

Coxarthrosis [arthrosis of hip](FG)

354

1681

1.53

12.35

1.2

59.14

63.97

u/l

0.47

236

1133

Selective serotonin reuptake inhibitors

674

2599

1.37

12.32

1.2

59.66

65.94

u/l

0.86

461

1765

Parodontitis or/and operation codes

458

1873

1.46

12.29

1.2

62.42

62.09

u/l

0.02

314

1275

Functional dyspepsia

185

1047

1.78

12.27

1.2

56.31

62.17

u/l

0.63

118

712

Giant cell arteritis with polymyalgia rheumatica

109

3.66

12.22

1.2

46.28

52.90

u/l

0.63

Neurological diseases

585

2108

1.40

12.18

1.2

62.05

74.66

u/l

1.78

394

1458

Benign neoplasm: Descending colon

196

2.90

12.14

1.3

1.2

58.71

58.74

u/l

0.00

139

Secondary and unspecified malignant neoplasm of lymph nodes

258

2.63

12.10

1.2

49.82

58.85

u/l

0.80

177

Benign neoplasm: Stomach

300

2.50

12.02

1.2

1.1

56.82

58.11

u/l

0.08

200

Injuries to the ankle and foot

430

2710

1.45

12.00

1.3

1.2

58.92

67.18

u/l

1.25

292

1847

Abnormal findings on examination of urine, without diagnosis

115

3.54

12.00

1.2

91.30

61.21

u/l

0.91

Myeloproliferative diseases

271

2.58

11.99

1.2

52.84

57.19

u/l

0.29

188

Carcinoma in situ of skin of trunk

4.92

11.95

1.2

1.1

55.95

53.71

u/l

0.05

L01XE Protein kinase inhibitors

171

3.03

11.95

1.2

59.68

52.25

u/l

0.51

127

Ankylosing spondylitis

301

2.49

11.93

1.1

52.19

66.35

u/l

1.09

188

Fracture of lower leg, including ankle

372

2502

1.49

11.93

1.2

60.96

65.17

u/l

0.44

270

1660

Secondary and unspecified malignant neoplasm of lymph nodes, excluding all cancers (controls excluding all cancers)

451

2.19

11.89

1.2

49.72

57.31

u/l

1.07

296

Factors influencing health status and contact with health services

189

523

1.82

11.85

1.2

1.1

61.78

75.10

u/l

0.64

138

346

Zoster [herpes zoster]

130

666

1.97

11.84

1.2

60.56

59.01

u/l

0.09

441

Vitamin deficiency

136

3.29

11.80

1.3

1.2

61.00

63.66

u/l

0.11

Vitamin deficiency, wide

136

3.29

11.80

1.3

1.2

61.00

63.66

u/l

0.11

Nonhereditary hypogammaglobulinemia

6.35

11.78

1.5

1.2

57.69

59.18

u/l

0.04

Pericarditis

3.83

11.78

1.5

1.2

58.64

66.06

u/l

0.37

Eosinophilia

5.68

11.73

1.2

195.73

68.89

u/l

0.38

Other/unspecified rheumatoid arthritis

100

467

2.16

11.72

1.1

1.2

54.35

57.10

u/l

0.28

313

Disorders of conjunctiva

535

3231

1.39

11.68

1.2

61.24

66.45

u/l

0.65

375

2184

L02BX Other hormone antagonists and related agents

132

3.31

11.67

2.6

1.2

180.51

52.44

u/l

1.89

Nonorganic sleeping disorders, excluding more controls

115

567

2.04

11.65

1.2

73.54

63.83

u/l

0.48

389

Thyrotoxicosis with diffuse goitre

110

534

2.08

11.65

1.1

1.2

85.64

57.68

u/l

2.05

367

Prurigo nodularis

4.38

11.55

1.2

46.95

53.10

u/l

0.43

Any operation in hilmo

7.36

11.50

1.2

1.0

59.62

120.25

u/l

—

Behavioural syndromes associated with physiological disturbances and physical factors

193

1126

1.72

11.50

1.2

67.04

67.69

u/l

0.03

138

759

Reactive arthropathies

253

2.60

11.49

1.3

1.1

52.87

60.23

u/l

0.63

167

Late syphilis

6.10

11.42

1.7

1.2

50.46

49.41

u/l

0.04

SLE, ICD10

110

3.53

11.32

1.2

40.53

54.46

u/l

1.34

SLE, strict definition

110

3.53

11.32

1.2

40.53

54.46

u/l

1.34

Psoriatic arthropathies, ICD10

371

2.29

11.30

1.2

58.81

55.40

u/l

0.30

260

Fentanyl

285

2.48

11.26

1.3

1.1

123.13

59.08

u/l

1.23

180

Other psoriatic arthropathies

353

2.32

11.24

1.2

58.84

55.73

u/l

0.26

245

Mental and behavioural disorders due to psychoactive substance use

367

2358

1.47

11.23

1.2

64.26

63.05

u/l

0.07

236

1612

Dental operations

443

1574

1.45

11.19

1.2

68.97

62.90

u/l

0.30

304

1057

Melanocytic naevi

169

959

1.77

11.15

1.3

1.2

69.20

57.27

u/l

0.64

114

631

Cardiac arrest

132

3.10

11.13

1.3

1.1

50.22

64.56

u/l

0.84

Exclusions for E4_PCOS_CONSORTIUM

497

2221

1.41

11.13

1.2

60.81

62.14

u/l

0.17

344

1506

Venous thromboembolism

361

2388

1.47

11.07

1.2

60.56

60.35

u/l

0.02

264

1573

Other general symptoms and signs

115

3.40

11.04

1.1

1.2

76.38

64.86

u/l

0.23

Myeloproliferative diseases (CML excluded)

241

2.61

11.04

1.2

50.23

57.10

u/l

0.50

170

Family history of malignant neoplasm

350

2.31

11.01

1.3

1.1

62.90

53.95

u/l

1.15

244

Dental pulpitis 2, only avohilmo

481

1736

1.42

11.00

1.2

67.44

65.28

u/l

0.14

325

1168

Malignant neoplasm of skin, excluding all cancers (controls excluding all cancers)

332

1505

1.51

10.98

1.3

1.2

58.79

57.41

u/l

0.15

216

974

Other/unspecified dorsalgia

253

1594

1.59

10.97

1.2

61.32

62.31

u/l

0.08

190

1026

Personal history of malignant neoplasm

103

3.56

10.91

1.2

1.1

58.75

70.82

u/l

0.54

Benign neoplasm: Caecum

302

2.41

10.91

1.1

53.78

58.98

u/l

0.31

197

Multiple myeloma, excluding all cancers (controls excluding all cancers)

103

3.55

10.89

1.3

1.1

57.10

53.29

u/l

0.22

Dental pulpitis 2

468

1685

1.43

10.89

1.2

66.74

65.24

u/l

0.10

320

1138

Juvenile arthritis (FINNGEN)

103

3.54

10.88

1.1

57.95

79.19

u/l

0.68

Systemic lupus erythematosus, unspecified

3.70

10.85

1.2

40.78

53.56

u/l

1.04

Systemic sclerosis (FG)

4.39

10.82

1.3

1.1

49.23

52.64

u/l

0.20

Other follicular disorders

198

2.76

10.77

1.2

68.30

54.52

u/l

0.79

143

Benign neoplasm: Liver/bile ducts

4.81

10.76

1.4

1.2

38.81

53.08

u/l

1.53

Duodenal ulcer

317

2.36

10.68

1.2

1.1

61.54

61.50

u/l

0.00

213

Coeliac disease

400

2.19

10.63

1.3

1.1

77.36

82.70

u/l

0.10

272

Spondylosis

363

2135

1.46

10.61

1.2

59.92

62.60

u/l

0.34

261

1409

Systemic lupus erythematosus

105

3.49

10.61

1.2

40.28

55.54

u/l

1.46

Acute sinusitis

325

2038

1.49

10.59

1.2

58.10

66.92

u/l

1.75

235

1370

Benign neoplasm: Rectum

110

554

2.00

10.57

1.2

57.32

58.34

u/l

0.04

348

Other and unspecified disorders of skin and subcutaneous tissue

189

2.79

10.56

1.2

59.21

54.25

u/l

0.18

131

Oesophagitis

146

3.06

10.52

1.3

1.2

56.34

64.83

u/l

0.48

107

Substance abuse

352

2304

1.46

10.51

1.2

62.77

63.44

u/l

0.04

225

1572

Extreme obesity with alveolar hypoventilation

121

3.28

10.45

1.2

1.1

53.16

55.41

u/l

0.15

Abnormal findings on diagnostic imaging of other body structures

456

2.10

10.43

1.2

64.39

59.34

u/l

0.23

309

Substance use, excluding alcohol

122

640

1.92

10.40

1.2

60.27

63.66

u/l

0.21

441

Dental pulpitis 4, only avohilmo

732

2911

1.32

10.39

1.2

61.26

65.67

u/l

0.58

490

1966

Injuries to the elbow and forearm

455

2953

1.40

10.39

1.2

68.00

64.00

u/l

0.43

296

2002

Gonarthrosis

429

1727

1.43

10.37

1.1

1.2

58.11

68.26

u/l

1.42

274

1148

Vasculitis limited to skin, not elsewhere classified

4.01

10.36

1.3

1.2

45.87

51.07

u/l

0.34

Stomatitis and related lesions

231

2.58

10.35

1.3

1.2

72.12

59.51

u/l

0.37

149

Benign neoplasm: Adrenal gland

209

2.67

10.27

1.3

1.1

49.44

54.95

u/l

0.64

141

Arthrosis

461

1802

1.41

10.27

1.2

60.98

67.78

u/l

0.74

313

1194

Other and unspecified vasculitis limited to skin

4.19

10.22

1.3

1.2

46.09

52.48

u/l

0.41

Arterial embolism and thrombosis

154

2.96

10.19

1.1

1.2

73.18

51.81

u/l

0.76

107

Vitamin D deficiency

5.40

10.17

1.5

1.1

69.87

64.52

u/l

0.14

Degenerative macular diseases

408

2.15

10.15

1.2

62.42

61.78

u/l

0.02

276

Non-follicular lymphoma

294

2.37

10.13

1.2

57.51

58.55

u/l

0.05

197

Persistent mood disorders

135

739

1.84

10.11

1.1

1.2

57.02

60.88

u/l

0.35

493

Benign neoplasm: Liver

4.89

10.06

1.4

1.2

39.53

53.28

u/l

1.27

Injuries to unspecified part of trunk, limb or body region

277

2.41

10.01

1.2

64.98

59.73

u/l

0.19

197

Dental caries 1, only avohilmo

540

2021

1.37

10.00

1.2

69.61

67.42

u/l

0.13

356

1375

Benign neoplasm: Sigmoid colon

128

692

1.86

10.00

1.3

1.2

55.30

60.79

u/l

0.38

459

Graves disease, strict definition

346

2.25

9.99

1.2

100.08

56.89

u/l

2.19

239

Drug-induced hypoglycaemia without coma

5.58

9.98

1.4

1.1

68.69

51.61

u/l

0.59

Dental caries 3, only avohilmo

572

2162

1.36

9.96

1.2

71.67

67.45

u/l

0.29

369

1481

Other and unspecified psoriasis

201

2.67

9.95

1.2

63.25

54.82

u/l

0.43

140

Macular pucker

106

540

1.98

9.91

1.3

1.2

55.89

64.28

u/l

0.76

364

Multiple myeloma and malignant plasma cell neoplasms

105

3.38

9.88

1.3

1.1

56.60

53.95

u/l

0.14

Hypopituitarism

179

2.77

9.86

1.2

64.46

84.40

u/l

0.50

129

Cardiomyopathies, Primary/intrinsic

335

2.26

9.86

1.1

1.2

100.70

70.01

u/l

0.31

219

Complications of cardiac and vascular prosthetic devices, implants and grafts

5.00

9.84

1.2

1.1

67.71

50.38

u/l

0.76

Asthma, hospital admissions , main diagnosis only

532

3543

1.35

9.77

1.2

57.57

66.90

u/l

2.36

397

2370

Squamous cell neoplasms and carcinomas of the skin, excluding all cancers (controls excluding all cancers)

305

2.31

9.75

1.3

1.1

66.91

59.54

u/l

0.32

191

Abnormalities of gait and mobility

389

2.15

9.72

1.2

108.73

71.67

u/l

0.32

258

Other intervertebral disc disorders

538

2434

1.36

9.71

1.2

54.94

63.43

u/l

2.48

342

1623

Pneumonia due to other infectious organisms, not elsewhere classified

3.90

9.71

1.1

1.2

68.57

57.15

u/l

0.43

Polymyalgia rheumatica

422

2.10

9.71

1.1

1.2

64.43

61.32

u/l

0.07

287

Symptoms and signs involving the nervous and musculoskeletal systems

368

2585

1.43

9.69

1.2

74.21

63.50

u/l

0.40

276

1700

Etanercept

181

2.74

9.68

1.1

56.44

61.40

u/l

0.26

125

Other coagulation defects

210

2.60

9.64

1.3

1.2

44.07

64.72

u/l

1.59

147

Phobic anxiety disorders

338

2.23

9.64

1.2

58.40

59.87

u/l

0.10

236

Nail disorders

270

2.40

9.63

1.2

83.72

60.12

u/l

0.52

195

Benign neoplasm of other and unspecified endocrine glands

398

2.13

9.57

1.3

1.1

49.57

57.93

u/l

1.34

260

Benign neoplasm: Pancreas

3.88

9.56

1.3

1.2

62.39

49.45

u/l

0.79

Bronchiectasis

259

2.42

9.54

1.3

1.1

55.07

62.41

u/l

0.72

177

Cardiomyopathy (excluding other)

353

2.20

9.52

1.1

1.2

99.53

66.63

u/l

0.35

228

Corns and callosities

200

2.63

9.50

1.4

1.2

71.18

55.36

u/l

1.07

144

Basal cell carcinoma, including avohilmo, excluding all cancers (controls excluding all cancers)

286

1308

1.51

9.49

1.2

60.95

57.93

u/l

0.35

195

841

Calculus of kidney and ureter

187

1143

1.64

9.48

1.2

65.44

60.91

u/l

0.27

129

744

Familial hypercholesterolemia, with ischemic heart disease

303

2.30

9.48

1.2

48.58

69.87

u/l

1.50

196

Hernia

617

3180

1.32

9.42

1.2

62.52

62.69

u/l

0.01

419

2149

Reactive arthropathies, FINNGEN

178

2.72

9.41

1.3

1.1

49.05

62.90

u/l

1.24

122

Other viral diseases

170

1013

1.68

9.40

1.2

70.65

73.20

u/l

0.10

127

686

Faecal incontinence

330

2.24

9.38

1.3

1.2

53.33

61.44

u/l

0.92

225

Benign neoplasm: Skin of trunk

3.45

9.34

1.5

1.2

56.15

61.65

u/l

0.26

Gastrojejunal ulcer

7.19

9.33

1.1

1.4

61.22

42.20

u/l

—

Opening and dilatation of root channel of tooth

179

2.71

9.32

1.2

55.23

54.91

u/l

0.02

128

Intracranial injury

341

2299

1.44

9.31

1.2

66.37

64.76

u/l

0.12

235

1548

Dental pulpitis 1, only avohilmo

726

2931

1.30

9.31

1.2

61.27

65.58

u/l

0.57

486

1979

Spinal stenosis

342

1862

1.44

9.30

1.2

54.83

61.88

u/l

1.82

223

1225

Benign neoplasm: Ascending colon

383

2.13

9.29

1.2

54.45

57.55

u/l

0.25

247

Basal cell carcinoma, excluding all cancers (controls excluding all cancers)

281

1290

1.51

9.29

1.2

60.88

57.68

u/l

0.37

191

829

Systemic sclerosis

3.89

9.28

1.3

1.2

49.23

55.88

u/l

0.47

Other and unspecified coagulation defects

141

2.95

9.26

1.2

39.57

58.39

u/l

2.18

Problems related to lifestyle

238

2.45

9.26

1.2

1.1

67.18

56.34

u/l

0.52

164

Neovascular glaucoma

115

3.18

9.22

1.3

1.2

48.67

53.16

u/l

0.36

Cerebral palsy and other paralytic syndromes

358

2.17

9.21

1.4

1.2

68.58

64.49

u/l

0.12

245

Drug-induced osteoporosis with pathological fracture

4.55

9.17

1.1

56.47

49.19

u/l

0.37

Fibromyalgia

314

2.25

9.16

1.3

1.2

57.23

57.05

u/l

0.01

215

Malignant neoplasm of kidney, except renal pelvis, excluding all cancers (controls excluding all cancers)

270

2.35

9.16

1.2

1.1

68.15

60.08

u/l

0.20

175

Fracture of shoulder and upper arm

231

1497

1.55

9.14

1.2

59.19

67.02

u/l

1.03

167

1001

Other juvenile arthritis

3.62

9.12

1.1

1.0

60.88

89.38

u/l

0.74

Urticaria

193

1202

1.61

9.09

1.2

80.32

65.10

u/l

0.27

134

815

Nonalcoholic steatohepatitis

6.56

9.09

1.2

1.3

55.83

52.47

u/l

—

Disorders of eyelid, lacrimal system and orbit

554

3280

1.33

9.09

1.2

66.96

62.84

u/l

0.18

373

2202

Adrenocortical insufficiency

101

3.33

9.07

1.2

70.35

56.94

u/l

0.46

Other infective otitis externa

182

2.67

9.05

1.3

1.2

44.38

56.85

u/l

1.19

125

Fracture of forearm

364

2419

1.41

9.04

1.2

67.63

62.56

u/l

0.60

244

1623

Coxarthrosis

321

1496

1.46

9.04

1.2

59.65

66.18

u/l

0.59

213

992

Stroke, excluding SAH

382

2021

1.41

9.00

1.2

54.25

63.99

u/l

1.96

256

1342

Sleep disorders

134

760

1.77

8.98

1.2

71.21

64.89

u/l

0.33

519

Glaucoma secondary to other eye disorders

117

3.13

8.97

1.3

1.2

48.67

53.11

u/l

0.35

Diseases of salivary glands

125

695

1.81

8.96

1.2

54.55

60.71

u/l

0.75

446

Delirium, not induced by alcohol and other psychoactive substances

336

2.19

8.94

1.2

66.93

59.93

u/l

0.32

216

Systemic sclerosis, icd10

3.79

8.94

1.3

1.2

49.23

53.73

u/l

0.28

Disorder of pancreatic internal secretion, other and/or unspecified

7.56

8.93

1.2

62.71

93.64

u/l

—

Conjunctivitis

471

3042

1.35

8.88

1.2

62.91

66.49

u/l

0.36

336

2058

Myalgia

149

875

1.71

8.84

1.2

57.89

60.57

u/l

0.24

101

576

Unspecified misadventure during surgical and medical care

162

2.76

8.79

1.3

1.2

50.03

53.24

u/l

0.25

112

Dislocation, sprain and strain of joint and ligaments of hip

3.39

8.79

1.3

1.2

49.60

49.73

u/l

0.01

Monoarthritis, not elsewhere classified

103

3.25

8.78

1.1

47.33

60.80

u/l

1.22

Unspecified fall

297

2030

1.46

8.76

1.2

78.52

65.16

u/l

0.39

215

1359

Pulmonary embolism

187

1167

1.61

8.75

1.2

61.98

63.51

u/l

0.09

140

757

Other abnormal findings of blood chemistry

119

3.07

8.73

1.2

54.63

50.99

u/l

0.19

Hernia of abdominal wall

276

1878

1.48

8.70

1.3

1.2

60.25

62.40

u/l

0.12

199

1240

Abnormalities of heart beat

217

1391

1.55

8.70

1.1

1.2

79.47

65.08

u/l

0.29

146

897

Biguanides

630

2987

1.30

8.69

1.2

56.34

63.79

u/l

1.79

423

2019

Personality disorders

163

985

1.66

8.68

1.1

1.2

56.98

60.08

u/l

0.29

117

671

Benign neoplasm: Transverse colon

341

2.16

8.68

1.2

52.88

59.13

u/l

0.45

232

Diseases of external ear

208

1334

1.57

8.68

1.2

69.81

68.72

u/l

0.04

122

885

Secondary right heart disease

109

3.17

8.68

1.2

51.74

59.20

u/l

0.27

Familial hypercholesterolemia

510

1.94

8.66

1.2

63.12

65.60

u/l

0.09

328

Other and unspecified types of non-Hodgkin lymphoma, hilmo, excluding all cancers

3.42

8.65

1.2

57.33

49.74

u/l

0.25

Keratitis

219

1422

1.55

8.65

1.3

1.2

57.25

63.30

u/l

0.90

165

940

Deficiency of other B group vitamins

4.13

8.57

1.3

1.1

63.08

57.49

u/l

0.24

Other disorders of lacrimal gland

233

1539

1.52

8.52

1.2

56.91

61.45

u/l

0.65

151

1031

Secondary uncertain malignant neoplasm

410

2.04

8.52

1.2

60.45

57.07

u/l

0.12

268

Nonorganic sleeping disorders

115

634

1.82

8.50

1.2

73.54

66.85

u/l

0.30

431

Amiodarone users

312

2.20

8.46

1.1

1.2

46.07

72.16

u/l

1.43

205

Hyphaema and other vascular disorders of iris and ciliary body

4.39

8.45

1.2

73.07

44.94

u/l

0.61

Chronic laryngitis and laryngotracheitis

103

550

1.89

8.44

1.2

61.64

58.85

u/l

0.22

365

Other diseases of the respiratory system

124

701

1.78

8.43

1.3

1.2

102.66

68.11

u/l

0.40

466

Other respiratory disorders and diseases

124

701

1.78

8.43

1.3

1.2

102.66

68.11

u/l

0.40

466

Any mental disorder, or suicide (or attempt), or psychic disorders complicating pregnancy, partum or puerperum or nerve system disorders, excluding more controls

160

970

1.66

8.42

1.2

52.97

60.07

u/l

1.15

655

Pulmonary heart disease

187

1180

1.59

8.38

1.2

61.98

63.28

u/l

0.07

140

764

Autoimmune hyperthyroidism

155

2.74

8.35

1.2

1.1

90.06

61.87

u/l

0.61

Other and unspecified urticaria

125

711

1.77

8.33

1.2

98.75

63.79

u/l

0.43

487

Malignant neoplasm of urinary organs, excluding all cancers (controls excluding all cancers)

314

2.18

8.32

1.2

1.1

72.74

58.28

u/l

0.44

201

Urolithiasis

195

1245

1.57

8.32

1.2

65.68

62.25

u/l

0.20

137

811

Disorders of adult personality and behaviour

169

1043

1.63

8.31

1.2

59.08

60.75

u/l

0.13

122

710

Retinal detachments and breaks

220

1449

1.53

8.17

1.2

54.32

62.78

u/l

1.54

140

971

Leiomyoma of uterus

297

1149

1.46

8.16

1.2

58.20

56.65

u/l

0.22

200

784

Rheumatism, unspecified

110

607

1.83

8.15

1.2

55.48

60.55

u/l

0.49

413

Fall on same level involving ice and snow

355

2561

1.39

8.14

1.2

63.90

62.90

u/l

0.09

248

1709

Other arthrosis

326

1644

1.42

8.13

1.2

53.97

67.25

u/l

2.63

231

1085

Erosion of teeth, including avohilmo

116

627

1.80

8.13

1.2

67.39

60.44

u/l

0.45

408

Other renal tubulo-interstitial diseases

3.82

8.11

1.2

1.1

79.94

56.09

u/l

1.19

Benign neoplasm: Tongue

3.82

8.10

1.2

52.72

55.13

u/l

0.09

Overexertion and strenuous or repetitive movements

305

2.18

8.08

1.3

1.2

48.02

57.86

u/l

1.34

213

Other skin changes

114

639

1.80

8.02

1.2

63.81

58.80

u/l

0.30

423

Carcinoma in situ of skin of trunk

3.58

8.01

1.2

1.1

55.95

50.22

u/l

0.16

Sciatica+with lumbago

320

2157

1.41

8.00

1.2

53.73

64.61

u/l

3.34

225

1430

Chronic rhinitis, nasopharyngitis and pharyngitis

208

1360

1.54

8.00

1.3

1.2

53.90

64.52

u/l

2.04

152

914

In situ neoplasms

232

1553

1.50

7.99

1.2

62.46

60.48

u/l

0.14

167

1032

Other malignant neoplasms of skin (=non-melanoma skin cancer), excluding all cancers (controls excluding all cancers)

283

1336

1.46

7.98

1.3

1.2

60.36

57.98

u/l

0.25

188

858

Other embolism and thrombosis

448

1.96

7.97

1.2

68.84

54.73

u/l

1.04

295

Dysphagia

147

886

1.67

7.96

1.3

1.2

91.67

68.41

u/l

0.32

102

579

Undetermined asthma, excluding more controls

393

2.02

7.95

1.3

1.1

58.43

66.08

u/l

0.61

250

Superficial injury of hip and thigh

448

1.95

7.95

1.3

1.1

68.67

56.25

u/l

0.86

290

Disorders of iron metabolism

4.75

7.93

1.2

76.25

55.24

u/l

—

Other pulmonary heart/vessel disease

126

2.90

7.93

1.2

50.28

60.76

u/l

0.46

Cerebrovascular diseases

472

2543

1.33

7.93

1.2

52.52

63.36

u/l

3.24

311

1706

Dental operations, only avohilmo

457

1736

1.35

7.92

1.2

61.60

66.95

u/l

0.55

318

1177

Benign neoplasm: Stomach

361

2.07

7.90

1.2

56.82

59.03

u/l

0.14

245

Poisoning by medicine

130

760

1.72

7.89

1.2

55.52

59.53

u/l

0.41

521

Benign neoplasm: Caecum

348

2.09

7.88

1.1

1.2

53.78

57.54

u/l

0.21

238

Malignant melanoma, excluding all cancers (controls excluding all cancers)

535

1.86

7.84

1.2

53.34

57.34

u/l

0.27

335

Injury of unspecified body region

214

2.41

7.83

1.2

65.92

57.61

u/l

0.24

150

Fall involving bed

3.58

7.73

1.1

1.2

80.74

69.71

u/l

0.25

Shoulder lesions

485

2242

1.33

7.73

1.2

56.71

64.60

u/l

1.45

322

1497

Other viral diseases, not elsewhere classified

107

594

1.81

7.70

1.3

1.2

75.53

80.98

u/l

0.16

411

Carcinoma in situ of skin of other and unspecified parts of face

180

2.52

7.66

1.2

1.1

68.56

62.89

u/l

0.23

115

Coronary revascularization (ANGIO or CABG)

283

1372

1.44

7.64

1.2

58.07

62.71

u/l

0.44

199

883

Panic disorder

420

1.96

7.63

1.2

65.71

56.93

u/l

0.43

291

Seborrhoeic dermatitis

280

2.20

7.62

1.4

1.1

57.78

59.71

u/l

0.10

189

Acute generalized exanthematous pustulosis

129

2.83

7.61

1.1

1.2

70.52

52.70

u/l

0.40

Alcohol-induced chronic pancreatitis

193

2.46

7.58

1.1

1.2

52.46

54.28

u/l

0.13

137

Malignant neoplasm of endocrine gland, excluding all cancers (controls excluding all cancers)

255

2.26

7.58

1.1

1.2

84.44

59.29

u/l

0.87

175

Mixed and other personality disorders

236

2.31

7.58

1.1

1.2

65.76

62.65

u/l

0.12

160

Chronic lymphocytic leukaemia

3.36

7.56

1.1

1.2

65.28

52.38

u/l

0.52

Dizziness and giddiness

476

2938

1.32

7.55

1.2

60.72

61.75

u/l

0.08

327

1961

Lactose intolerance

3.27

7.55

1.2

49.36

59.02

u/l

0.45

Other specified and unspecified personality disorders

262

2.23

7.53

1.2

59.27

56.25

u/l

0.16

183

Malignant neoplasm of bladder, excluding all cancers (controls excluding all cancers)

300

2.14

7.53

1.2

1.1

52.51

54.98

u/l

0.13

189

Mental and behavioural disorders due to alcohol

291

2002

1.42

7.52

1.1

1.2

66.38

63.66

u/l

0.14

190

1366

Cyst of kidney

194

2.45

7.51

1.2

59.14

58.31

u/l

0.04

139

Unspecified nephritic syndrome

3.73

7.50

1.3

94.39

52.61

u/l

1.08

Fissure and fistula of anal and rectal regions

147

901

1.64

7.49

1.1

1.2

51.72

65.16

u/l

2.59

109

615

Benign neoplasm: Adrenal gland

244

2.28

7.48

1.3

1.2

49.44

56.40

u/l

0.86

176

Other endocrine disorders

125

2.80

7.44

1.2

1.1

83.04

149.86

u/l

0.76

Procreative management

201

1114

1.53

7.41

1.3

1.2

76.87

67.81

u/l

0.46

147

784

Stroke, including SAH

395

2166

1.35

7.40

1.2

52.99

63.59

u/l

2.53

265

1445

Hidradenitis suppurativa

3.07

7.34

1.2

71.85

54.73

u/l

0.61

Non-allergic asthma (mode), excluding more controls

111

628

1.76

7.34

1.2

1.1

52.23

70.22

u/l

2.86

409

Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances

547

1.82

7.33

1.2

57.15

59.59

u/l

0.17

380

Suppurative and necrotic conditions of lower respiratory tract

143

2.69

7.33

1.5

1.2

101.70

57.02

u/l

0.58

Dermatitis due to substances taken internally

149

2.65

7.30

1.2

70.20

56.19

u/l

0.29

104

Atopic dermatitis

315

1932

1.39

7.27

1.2

65.61

69.85

u/l

0.34

213

1316

Small fibre neuropathy

3.31

7.15

1.3

1.2

45.00

51.90

u/l

0.58

Syphilis

3.31

7.15

1.6

1.2

46.79

54.44

u/l

0.45

Protozoal diseases

3.31

7.14

1.1

1.2

57.15

58.98

u/l

0.05

Other diseases of upper respiratory tract

730

3051

1.25

7.12

1.3

1.2

60.64

68.32

u/l

1.13

480

2093

Pure hyperglyceridaemia

3.82

7.11

1.2

1.3

58.36

45.62

u/l

0.87

Visual disturbances and blindness

308

2224

1.39

7.10

1.2

68.96

63.14

u/l

0.15

213

1471

Diffuse large B-cell lymphoma, excluding all cancers (controls excluding all cancers)

101

3.01

7.10

1.1

75.83

52.04

u/l

0.52

Diffuse large B-cell lymphoma, helper endpoint

101

3.01

7.10

1.1

75.83

52.04

u/l

0.52

Diseases of the ear and mastoid process

762

3106

1.24

7.07

1.2

62.72

65.97

u/l

0.39

497

2153

Insomnia

532

1.82

7.06

1.2

68.91

65.87

u/l

0.11

370

Poisoning by drugs, medicaments and biological substances

139

854

1.64

7.04

1.2

54.04

58.97

u/l

0.61

586

Diseases of the myoneural junction and muscle

384

1.97

7.04

1.2

1.1

63.43

65.40

u/l

0.05

263

Other diseases of lip and oral mucosa

101

569

1.79

7.04

1.3

1.2

53.56

64.45

u/l

1.46

376

Carcinoma in situ of breast, intraductal

310

2.09

7.02

1.2

62.68

55.62

u/l

0.44

209

Other diseases of jaws

188

2.42

7.02

1.2

60.04

49.76

u/l

0.61

127

Hodgkin lymphoma

3.54

7.02

1.1

1.2

57.39

54.84

u/l

0.07

Benign neoplasm: Liver/bile ducts

3.45

7.01

1.4

1.2

38.81

52.26

u/l

1.60

Social phobias

182

2.43

7.00

1.2

52.83

56.72

u/l

0.24

122

L02BB Anti-androgens

239

2.24

6.95

2.3

1.1

154.23

61.85

u/l

1.60

148

Use of eye-antiallergens (taken as indicator of allergic/atopic conjunctivitis)

335

2419

1.37

6.94

1.2

65.52

61.43

u/l

0.34

240

1637

Other complications of surgical and medical care, not elsewhere classified

298

2.10

6.93

1.2

1.1

54.53

72.59

u/l

0.73

201

Mental and behavioural disorders due to alcohol, excluding acute intoxication

251

1755

1.43

6.93

1.2

65.32

63.97

u/l

0.06

161

1188

Generalized skin eruption due to drugs and medicaments

108

2.91

6.92

1.2

1.1

74.55

53.32

u/l

0.43

Infections with a predominantly sexual mode of transmission

172

1115

1.55

6.92

1.2

60.32

59.04

u/l

0.08

102

767

Undetermined asthma

414

1.92

6.91

1.3

1.1

58.43

62.88

u/l

0.32

264

Dermatophytosis

429

1.90

6.89

1.2

68.89

63.73

u/l

0.17

281

Drug-induced cataract

3.24

6.89

1.3

1.1

168.83

56.86

u/l

0.89

Obesity related asthma

210

1423

1.48

6.89

1.3

1.2

57.83

62.52

u/l

0.45

149

927

Haemorrhage, not elsewhere classified

3.15

6.88

1.4

1.2

56.25

66.18

u/l

0.37

KRA_PSY_EATING, excluding more controls

153

2.56

6.88

1.4

1.2

73.42

90.13

u/l

0.25

100

Other other unspecified disorders of the circulatory system

114

2.85

6.87

1.3

1.2

52.47

52.95

u/l

0.02

Scar conditions and fibrosis of skin

114

2.85

6.86

1.1

1.2

63.32

55.35

u/l

0.55

Sequelae of other external causes

160

2.53

6.86

1.2

1.1

74.56

50.80

u/l

0.62

111

Rash and other nonspecific skin eruption

340

2.02

6.84

1.3

1.2

75.24

55.31

u/l

0.90

230

DVT of lower extremities and pulmonary embolism

258

1815

1.42

6.81

1.3

1.2

61.21

60.11

u/l

0.08

196

1195

Traumatic subdural haemorrhage

382

1.94

6.79

1.1

1.2

63.15

73.89

u/l

0.42

259

Symptoms and signs involving speech and voice

210

1428

1.48

6.78

1.2

62.26

61.50

u/l

0.05

144

949

Need for other prophylactic measures

167

2.48

6.77

1.2

56.52

65.67

u/l

0.47

116

Benign neoplasm: Small intestine

104

2.93

6.76

1.1

53.00

53.17

u/l

0.01

Superficial injury of lower leg

145

911

1.60

6.73

1.2

56.79

69.08

u/l

1.27

607

Other diseases of oesophagus

275

2.12

6.72

1.3

1.2

146.58

59.63

u/l

0.56

191

Chronic sinusitis

267

1901

1.41

6.70

1.3

1.2

52.87

62.78

u/l

3.40

201

1269

Mental and behavioural disorders due to tobacco

269

2.14

6.70

1.2

52.03

57.00

u/l

0.35

190

Fracture of skull and facial bones

118

705

1.68

6.69

1.2

93.14

60.33

u/l

1.25

482

Benign neoplasm of other and unspecified endocrine glands

455

1.86

6.69

1.3

1.2

49.57

58.42

u/l

1.39

310

Otitis externa

131

805

1.64

6.67

1.3

1.2

75.07

63.33

u/l

0.50

540

Excessive attrition of teeth

226

832

1.48

6.66

1.2

67.35

59.53

u/l

0.76

151

535

Smoking dependency

270

2.13

6.64

1.2

52.03

56.03

u/l

0.27

192

Other and unspecified nail disorders

3.63

6.63

1.2

91.80

58.15

u/l

1.11

Allergic conjunctivitis

347

2542

1.35

6.62

1.2

65.29

61.50

u/l

0.32

247

1719

Iridocyclitis

141

884

1.60

6.62

1.2

51.70

66.29

u/l

1.79

105

590

Ischaemic Stroke, excluding all haemorrhages

342

1910

1.36

6.62

1.2

52.44

64.83

u/l

2.84

224

1270

Other otitis externa (chronic)

206

2.31

6.61

1.1

1.2

63.17

60.46

u/l

0.09

147

Emergency coronary revascularization (for ACS)

317

1662

1.37

6.58

1.2

56.56

63.93

u/l

0.77

224

1078

Squamous cell neoplasms and carcinomas of the skin

359

1.96

6.56

1.3

1.2

66.91

62.75

u/l

0.16

238

Barrett oesophagus

117

2.77

6.55

1.1

1.2

45.15

59.04

u/l

0.65

Injuries to the wrist and hand

602

3478

1.26

6.55

1.2

63.79

65.74

u/l

0.20

382

2394

Specific personality disorders

133

824

1.62

6.55

1.2

59.67

59.04

u/l

0.04

556

Obsessive-compulsive disorder

134

2.63

6.55

1.2

41.29

61.51

u/l

2.09

Acute and subacute iridocyclitis

122

741

1.66

6.52

1.2

50.03

60.99

u/l

1.48

495

Artificial joint re-operation

214

2.27

6.50

1.2

55.73

55.07

u/l

0.03

153

Retinal detachment with retinal break

438

1.86

6.49

1.1

1.2

52.00

62.71

u/l

1.15

296

Neuromuscular dysfunction of bladder

273

2.11

6.46

1.4

1.2

53.86

60.07

u/l

0.36

168

Benign neoplasm: Liver

3.45

6.46

1.4

1.2

39.53

50.13

u/l

1.08

Other disorders of iris and ciliary body

3.34

6.44

1.2

71.94

48.13

u/l

0.53

Other obstructive and reflux uropathy

2.95

6.43

1.1

82.65

58.87

u/l

0.59

Other disorders of the musculoskeletal system and connective tissue

541

1.77

6.43

1.2

60.31

58.96

u/l

0.08

368

Sodium-glucose co-transporter 2 (SGLT2) inhibitors

158

1025

1.55

6.42

1.2

53.14

62.11

u/l

1.23

110

687

Filling of root of tooth

102

2.89

6.40

1.4

1.2

52.95

61.85

u/l

0.40

Superficial injury of head

127

784

1.63

6.36

1.1

1.2

58.25

63.67

u/l

0.47

524

Transport accidents

254

1602

1.41

6.34

1.2

60.96

66.25

u/l

0.46

171

1090

Carcinoma in situ of skin of lower limb, including hip

4.29

6.32

1.3

1.2

52.18

49.96

u/l

0.08

Benign neoplasm: Rectum, anus and anal canal

125

771

1.63

6.30

1.2

58.72

63.09

u/l

0.20

505

Asthma and opportunity respiratory infection

143

2.55

6.30

1.3

1.2

63.58

53.64

u/l

0.42

100

Hepatocellular carcinoma

3.91

6.29

1.0

1.1

43.92

47.35

u/l

0.17

Other specified/unspecified bacterial intestinal infections

192

2.31

6.27

1.2

48.14

55.51

u/l

0.68

135

Follow-up care involving plastic surgery

120

2.70

6.27

1.1

1.2

48.57

52.93

u/l

—

Visual impairment including blindness (binocular or monocular)

192

2.31

6.27

1.2

69.46

61.98

u/l

0.28

131

Respiratory insufficiency

198

2.29

6.25

1.2

1.1

176.32

69.93

u/l

0.43

123

Convulsions, not elsewhere classified

116

694

1.66

6.24

1.1

1.2

61.22

72.74

u/l

0.77

445

Generalized anxiety disorder

437

1.84

6.21

1.1

1.2

62.25

55.20

u/l

0.51

310

Diseases of spleen

4.04

6.20

1.1

1.2

57.25

51.50

u/l

0.21

Benign neoplasm of eye and adnexa

291

2.04

6.20

1.1

1.2

62.05

68.27

u/l

0.18

192

Asthma/COPD (KELA code 203)

580

3266

1.25

6.20

1.2

57.09

67.73

u/l

2.87

415

2193

Disorders of lacrimal system

269

1947

1.39

6.20

1.2

57.29

62.04

u/l

0.80

170

1297

Monoamine oxidase A inhibitors

460

1.82

6.17

1.2

58.19

62.44

u/l

0.23

309

Anterior Iridocyclitis

127

792

1.61

6.13

1.2

50.30

60.30

u/l

1.38

534

Other neurological diseases

440

2745

1.29

6.12

1.2

58.04

63.30

u/l

0.80

304

1821

Suicide or other Intentional self-harm

144

926

1.56

6.10

1.2

54.30

59.53

u/l

0.65

628

Polycythaemia vera

3.12

6.06

1.1

1.2

52.25

55.77

u/l

0.14

Drugs, medicaments and biological substances causing adverse effects in therapeutic use

267

2.08

6.04

1.1

49.10

73.14

u/l

1.15

186

Other and unspecified types of non-Hodgkin lymphoma, hilmo

111

2.74

6.04

1.2

57.33

55.12

u/l

0.06

Soft tissue disorders related to use, overuse and pressure

166

1104

1.51

6.03

1.2

55.84

62.19

u/l

0.69

116

735

Sequelae of cerebrovascular disease

201

1215

1.46

6.02

1.2

53.53

63.11

u/l

1.57

125

795

Other disorders of veins

256

1846

1.39

6.02

1.2

54.19

61.19

u/l

0.95

166

1219

Complications of other internal prosthetic devices, implants and grafts

100

2.84

6.01

1.2

52.74

53.28

u/l

0.02

Malignant neoplasm of colon, excluding all cancers (controls excluding all cancers)

101

597

1.70

6.01

1.1

1.2

83.68

57.18

u/l

1.09

381

Impacted cerumen

295

2.02

5.99

1.1

1.2

62.71

64.96

u/l

0.09

204

Pustular psoriasis

165

2.39

5.99

1.1

1.2

62.41

74.45

u/l

0.24

114

Polyarthrosis

131

793

1.59

5.98

1.2

52.03

61.89

u/l

1.74

520

Chorioretinal inflammation

3.02

5.98

1.2

45.07

53.66

u/l

0.58

Other/unspecified synovitis and tenosynovitis

407

1.86

5.98

1.2

61.63

58.86

u/l

0.14

275

Viral warts

302

2.00

5.98

1.3

1.1

68.44

59.60

u/l

0.35

211

Pyothorax

106

2.77

5.97

1.7

1.2

118.47

54.08

u/l

0.63

Ventral hernia

149

971

1.54

5.96

1.3

1.2

56.06

64.15

u/l

1.13

108

634

Multiple myeloma and malignant plasma cell neoplasms

141

2.51

5.96

1.3

1.2

56.60

50.14

u/l

0.44

Malignant neoplasm of digestive organs

221

1533

1.42

5.95

1.1

1.2

71.88

60.82

u/l

0.57

161

993

Bipolar affective disorders

105

629

1.68

5.95

1.2

53.85

56.63

u/l

0.26

428

Malignant neoplasm of liver and intrahepatic bile ducts

3.08

5.94

1.0

1.2

41.61

54.70

u/l

1.15

Benign neoplasm: Rectum

110

668

1.66

5.93

1.2

57.32

63.89

u/l

0.28

441

Other problems related to primary support group, including family circumstances

308

1.97

5.93

1.2

273.06

72.97

u/l

1.04

210

Other disorders of bone

113

691

1.64

5.92

1.2

1.1

79.06

62.32

u/l

0.60

467

Malignant neoplasm of intrahepatic ducts, biliary tract and gallbladder

118

2.66

5.91

1.0

1.1

50.67

52.23

u/l

0.06

Use of pramipexole

142

918

1.56

5.90

1.2

62.08

62.31

u/l

0.01

606

Benign neoplasm: Duodenum

3.45

5.89

1.2

56.86

50.95

u/l

0.30

Lung cancer and mesothelioma

105

536

1.68

5.89

1.2

66.27

66.49

u/l

0.01

337

Spinal enthesopathy

3.14

5.88

1.1

1.2

59.94

55.19

u/l

0.18

Other headache syndromes

258

1873

1.38

5.86

1.2

54.09

61.39

u/l

1.60

176

1250

L01XX Other antineoplastic agents

167

2.36

5.83

1.3

1.2

44.62

50.78

u/l

0.48

120

Exposure to other and unspecified inanimate mechanical forces

192

2.26

5.83

1.1

1.2

53.96

64.96

u/l

0.76

136

Melanocytic naevi of scalp and neck

3.83

5.83

1.5

1.2

59.17

51.19

u/l

0.22

Follow-up examination after treatment for malignant neoplasms

368

1.89

5.82

1.2

1.1

62.40

62.60

u/l

0.01

242

Other specified disorders of kidney and ureter

102

2.79

5.82

1.1

103.73

55.30

u/l

1.11

Anosmia

4.00

5.80

1.2

1.1

47.64

48.71

u/l

0.06

Thyrotoxicosis with toxic multinodular goitre

212

2.19

5.80

1.2

71.81

53.65

u/l

0.95

142

Lactose intolerance, other/unspecified

3.11

5.79

1.2

51.89

61.31

u/l

—

Persons with potential health hazards related to socioeconomic and psychosocial circumstances

145

935

1.54

5.78

1.1

1.2

142.63

64.76

u/l

1.14

637

Other keratitis

348

1.91

5.76

1.2

1.1

53.59

63.75

u/l

0.91

238

Benign neoplasm: Anus and anal canal

3.28

5.75

1.2

63.57

56.07

u/l

0.24

Coronary artery bypass grafting

151

751

1.54

5.74

1.2

61.20

66.90

u/l

0.31

101

475

Inflammatory diseases of the central nervous system

246

2.09

5.72

1.2

58.55

59.49

u/l

0.04

171

Hyperfunction of pituitary gland

126

2.56

5.71

1.3

1.2

62.52

72.41

u/l

0.28

Deforming dorsopathies

176

1199

1.47

5.71

1.2

63.10

65.05

u/l

0.15

126

781

Early onset COPD

141

919

1.54

5.67

1.1

1.2

54.57

64.57

u/l

1.16

604

Carcinoma in situ of skin

201

2.21

5.66

1.1

1.2

51.73

59.10

u/l

0.37

136

Non-allergic asthma (mode)

111

678

1.63

5.64

1.2

52.23

68.56

u/l

2.57

440

Somatoform disorder

100

601

1.67

5.63

1.2

56.25

57.30

u/l

0.06

413

Postprocedural musculoskeletal disorders, not elsewhere classified

228

2.13

5.62

1.2

62.42

58.05

u/l

0.17

166

Internal derangement of knee

209

1471

1.42

5.62

1.2

56.76

66.93

u/l

1.48

135

959

Myocardial infarction, with ST-elevation

571

1.69

5.61

1.1

1.2

103.67

67.12

u/l

0.29

368

Malignant neoplasm of stomach, excluding all cancers (controls excluding all cancers)

133

2.50

5.61

1.2

52.29

52.32

u/l

0.00

Colorectal cancer, excluding all cancers (controls excluding all cancers)

143

905

1.53

5.61

1.1

1.2

83.41

56.48

u/l

1.00

575

Childhood asthma (age<16), excluding more controls

209

2.06

5.61

1.3

1.1

69.14

89.20

u/l

0.86

141

Other and unspecified drugs and medicaments

248

2.07

5.61

1.1

1.2

49.14

69.69

u/l

0.84

175

severe traumatic brain injury, does not include concussion

119

748

1.60

5.60

1.2

74.41

63.57

u/l

0.52

491

Unspecified acute lower respiratory infection

438

1.79

5.59

1.2

57.25

64.19

u/l

0.29

291

Injury, poisoning and certain other consequences of external causes

346

1305

1.33

5.58

1.2

63.61

72.44

u/l

0.60

238

897

Other disorders of nervous system

209

2.17

5.57

1.4

1.2

57.93

57.40

u/l

0.02

147

Pustulosis palmaris et plantaris

146

2.43

5.56

1.1

1.2

64.11

53.64

u/l

0.64

101

Other and unspecified acquired haemolytic anaemias

5.39

5.56

1.2

39.18

41.07

u/l

0.09

Other orthopaedic follow-up care

152

2.39

5.56

1.3

1.2

55.96

54.55

u/l

0.07

102

Restless leg syndrome

432

1.80

5.55

1.1

1.2

58.94

58.31

u/l

0.03

295

Childhood asthma (age<16)

210

2.05

5.55

1.3

1.1

69.14

88.73

u/l

0.83

142

Fibroblastic disorders

142

932

1.53

5.53

1.2

57.22

64.69

u/l

0.74

612

Benign neoplasm: Ascending colon

462

1.77

5.52

1.2

54.45

61.02

u/l

0.63

314

Other symptoms and signs involving cognitive functions and awareness

264

1821

1.36

5.51

1.1

1.2

57.48

61.35

u/l

0.43

175

1211

Cysts of oral region, not elsewhere classified

105

2.69

5.51

1.3

1.2

130.87

55.73

u/l

0.41

Atopic dermatitis, strict definition with reimbursement

157

1022

1.49

5.46

1.2

73.44

74.73

u/l

0.04

101

693

Polyuria

123

785

1.57

5.44

1.3

1.2

53.53

65.59

u/l

1.34

528

Dipeptidyl peptidase 4 (DPP-4) inhibitors

399

1.82

5.41

1.1

1.2

57.12

65.68

u/l

0.63

271

Neuralgia and neuritis, unspecified

148

2.39

5.40

1.1

1.2

61.10

56.75

u/l

0.19

105

Acute suppurative otitis media

119

703

1.59

5.40

1.3

1.2

87.69

74.52

u/l

0.46

490

Paracetamol of NSAID medication

269

1.75

5.39

1.2

60.52

101.27

u/l

1.28

193

Phlebitis and thrombophlebitis (not including DVT)

140

923

1.52

5.36

1.2

57.96

61.84

u/l

0.28

600

Alcohol use disorder, ICD-based

226

1631

1.39

5.36

1.2

67.67

63.64

u/l

0.16

143

1097

Malignant neoplasm of respiratory system and intrathoracic organs, excluding all cancers (controls excluding all cancers)

122

650

1.58

5.36

1.1

1.2

63.75

56.27

u/l

0.50

402

Temporomandibular joint disorders

541

1.69

5.35

1.2

1.1

59.30

64.32

u/l

0.35

344

Special screening examination for other diseases and disorders

239

2.06

5.35

1.2

1.1

156.35

63.38

u/l

0.47

164

Malignant melanoma of skin, excluding all cancers (controls excluding all cancers)

437

1.77

5.35

1.2

50.08

57.19

u/l

0.51

273

Malignant neoplasm of thyroid gland, excluding all cancers (controls excluding all cancers)

226

2.10

5.34

1.1

1.2

89.23

57.15

u/l

0.88

152

Fracture of foot, except ankle

134

876

1.54

5.33

1.4

1.2

57.77

62.03

u/l

0.40

582

Carcinoma in situ of skin of other and unspecified parts of face

213

2.13

5.33

1.2

68.56

59.93

u/l

0.39

140

Hodgkin lymphoma, hilmo

2.95

5.32

1.1

1.2

57.39

51.80

u/l

0.19

Benign neoplasm: Rectosigmoid junction

2.81

5.32

1.2

53.20

51.33

u/l

0.08

Visual disturbances

276

2059

1.34

5.32

1.2

68.93

63.54

u/l

0.12

194

1360

Benign neoplasm: Skin of trunk

131

2.47

5.30

1.5

1.2

56.15

56.82

u/l

0.03

Bacterial, viral and other infectious agents

240

2.06

5.30

1.2

71.45

75.91

u/l

0.09

179

COPD-related respiratory insufficiency

380

1.83

5.30

1.1

1.2

60.77

60.67

u/l

0.00

256

Other disorders of cornea

309

1.92

5.29

1.1

1.2

53.32

58.88

u/l

0.52

216

Other and unspecified disorders of vitreous body

262

1931

1.35

5.29

1.2

61.24

u/l

0.00

174

1275

Malignant neoplasm of other endocrine glands and related structures

+∞

5.29

1.4

0.0

72.20

—

u/l

—

Aortic aneurysm

117

730

1.58

5.29

1.2

48.16

62.80

u/l

2.04

470

Unspecified urinary incontinence

324

1.90

5.26

1.2

50.00

57.92

u/l

1.26

223

Ingrowing nail

150

2.36

5.25

1.2

1.1

84.31

58.92

u/l

0.32

107

Allergic asthma (mode), excluding more controls

119

746

1.57

5.24

1.2

1.1

64.08

68.86

u/l

0.34

484

Gonarthrosis,primary

577

2953

1.23

5.23

1.2

58.48

61.67

u/l

0.48

360

2011

Trochanteric bursitis

546

1.68

5.20

1.2

47.88

62.22

u/l

1.96

374

Pulmonary oedema

4.06

5.18

1.4

1.1

51.78

52.96

u/l

—

Benign neoplasm: Choroid

151

2.34

5.18

1.1

1.2

63.67

55.78

u/l

0.34

104

Other eating disorders

2.70

5.17

1.2

1.1

65.82

102.27

u/l

0.43

Any mental disorder, or suicide (or attempt), or psychic disorders complicating pregnancy, partum or puerperium or nerve system disorders

160

1093

1.47

5.16

1.2

52.97

59.99

u/l

1.08

735

Malignant neoplasm of kidney, except renal pelvis

270

1.98

5.16

1.2

71.76

60.14

u/l

0.27

191

Dentofacial anomalies [including malocclusion]

151

1010

1.48

5.12

1.2

106.78

61.82

u/l

0.77

104

663

Abscess of anal and rectal regions

230

2.06

5.11

1.1

66.91

61.03

u/l

0.25

157

Other specified/unspecified inflammatory spondylopathies

146

2.35

5.09

1.1

1.2

51.65

67.59

u/l

0.66

Other nonscarring hair loss

4.57

5.07

1.1

1.3

62.00

61.12

u/l

—

Melanocytic naevi

169

1174

1.44

5.02

1.3

1.2

69.20

60.29

u/l

0.43

114

777

Secondary malignant neoplasm of respiratory and digestive organs, excluding all cancers (controls excluding all cancers)

559

1.65

5.01

1.2

64.25

57.15

u/l

0.53

361

Asthma and allergy, excluding more controls

332

1.85

5.00

1.3

1.1

78.24

76.16

u/l

0.07

229

Viral hepatitis

212

2.09

4.99

1.3

1.2

64.81

56.57

u/l

0.51

150

Disorders of breast

317

2255

1.31

4.99

1.2

57.47

58.11

u/l

0.10

224

1512

Carpal tunnel syndrome

382

2710

1.28

4.98

1.2

58.63

60.33

u/l

0.29

273

1817

Other viral hepatitis

173

2.21

4.97

1.3

1.2

65.47

59.39

u/l

0.33

119

Left bundle-branch block

193

2.14

4.94

1.0

1.2

68.48

60.44

u/l

0.37

133

Vaginitis/vulvovaginitis/vulvitis/abscess of vulva

600

1.62

4.93

1.2

54.71

60.85

u/l

0.61

408

238

1653

1.36

4.91

1.2

62.31

60.05

u/l

0.16

154

1092

Scoliosis

241

2.00

4.88

1.3

1.2

67.05

56.14

u/l

0.64

158

Melanocytic naevi of trunk

311

1.88

4.87

1.2

1.1

88.76

58.97

u/l

0.55

209

Lung diseases due to external agents

420

1.75

4.87

1.2

48.48

61.41

u/l

1.47

275

Sulfonylureas

213

1231

1.39

4.85

1.2

54.26

65.60

u/l

1.33

145

813

Superficial injury of abdomen, lower back and pelvis

458

1.71

4.84

1.3

1.1

116.47

64.83

u/l

0.44

303

Injuries to the shoulder and upper arm

494

3363

1.23

4.80

1.2

58.91

66.08

u/l

1.37

343

2261

Voice disturbances

165

1152

1.44

4.79

1.3

1.2

62.91

59.80

u/l

0.22

120

765

Pneumonia derived septicemia

2.77

4.79

1.4

1.2

127.17

60.52

u/l

0.61

Malignant neoplasm of endocrine gland

250

1.98

4.79

1.2

81.79

58.55

u/l

0.68

175

Emotionally unstable personality disorder

342

1.82

4.77

1.2

63.02

59.81

u/l

0.13

230

Dental pulpitis 3

181

2.00

4.76

1.3

1.2

81.22

133.51

u/l

1.10

134

Other inflammation of eyelid

476

1.69

4.75

1.3

1.2

119.64

60.45

u/l

0.47

328

Primary gonarthrosis, bilateral

323

2188

1.30

4.75

1.2

56.69

60.99

u/l

0.74

188

1468

Colon adenocarcinoma, excluding all cancers (controls excluding all cancers)

321

1.85

4.75

1.1

88.61

60.33

u/l

0.72

205

Other congenital malformations

237

1.99

4.73

1.2

1.1

69.06

93.06

u/l

0.63

163

Benign neoplasm of urinary organs

108

2.52

4.72

1.2

1.1

36.53

54.25

u/l

3.23

Other/unspecified reactive arthropathies

204

2.08

4.69

1.3

1.2

49.76

57.69

u/l

0.61

143

COPD, hospital admissions 3, with asthma pneumonia sepsis

145

840

1.47

4.69

1.2

56.39

62.78

u/l

0.53

108

559

Diffuse large B-cell lymphoma

127

2.39

4.66

1.1

1.2

75.83

52.41

u/l

0.51

Hallux rigidus

532

1.64

4.66

1.1

1.2

52.51

62.75

u/l

1.57

350

Delivery, wide proxy

116

936

0.66

4.65

1.3

1.2

58.96

57.94

u/l

0.08

635

Malignant neoplasm of other connective and soft tissue, excluding all cancers (controls excluding all cancers)

2.60

4.65

1.1

1.2

55.72

51.07

u/l

0.29

Follicular lymphoma

103

2.55

4.64

1.2

48.53

55.47

u/l

0.48

Acidosis

3.26

4.64

1.2

69.55

56.46

u/l

0.26

Congenital malformations and deformations of the musculoskeletal system

238

1.98

4.62

1.1

1.2

159.97

95.24

u/l

0.31

166

Dental pulpitis 3, only avohilmo

166

2.03

4.61

1.3

1.2

83.09

133.52

u/l

0.95

126

Other enthesopathies

181

1295

1.40

4.60

1.2

59.38

61.92

u/l

0.22

131

859

Car occupant injured in other and unspecified transport accidents

627

1.59

4.60

1.2

58.48

60.35

u/l

0.12

430

Retinal vascular disorders

398

1.74

4.59

1.2

60.53

61.06

u/l

0.03

268

Behavioural and emotional disorders with onset usually occurring in childhood and adolescence

408

1.70

4.59

1.3

1.2

96.69

102.75

u/l

0.10

280

Asthma and allergy

342

1.80

4.58

1.3

1.1

78.24

75.15

u/l

0.11

233

Lumbar disc prolapse

373

2344

1.27

4.58

1.2

55.05

63.95

u/l

2.19

246

1556

Unspecific neurodegenerative disorder

114

1185

0.66

4.56

1.1

1.2

59.76

60.86

u/l

0.07

781

Other specified/unspecified necrotizing vasculopathies

3.90

4.56

1.1

42.29

53.57

u/l

—

Artrosis, including avohilmo

526

2358

1.23

4.55

1.2

60.80

64.31

u/l

0.39

363

1595

Abrasion of teeth

150

759

1.46

4.52

1.2

68.48

54.67

u/l

1.22

481

Volvulus

2.90

4.51

1.5

1.1

61.47

43.49

u/l

0.80

Psoriasis (vulgaris), strict definition

2.68

4.50

1.2

50.13

52.22

u/l

0.10

Colonic or urogenital fistula

160

1125

1.43

4.50

1.1

1.2

51.55

63.49

u/l

2.57

118

746

Fracture at wrist and hand level

180

1291

1.40

4.50

1.2

65.53

64.30

u/l

0.07

116

885

Other disorders of optic [2nd] nerve and visual pathways

168

2.16

4.47

1.2

63.28

56.64

u/l

0.17

124

161

1003

1.43

4.45

1.2

66.59

60.53

u/l

0.39

681

Coronary angioplasty

208

1169

1.37

4.45

1.2

52.49

62.82

u/l

1.58

152

747

Other symptoms and signs involving the nervous and musculoskeletal systems

241

1814

1.33

4.45

1.2

64.47

63.81

u/l

0.04

185

1188

Benign neoplasm: Small intestine

130

2.34

4.45

1.1

1.2

53.00

49.29

u/l

0.25

Retinal vascular occlusion

395

1.73

4.43

1.2

61.08

60.35

u/l

0.04

265

Injury of eye and orbit

425

1.70

4.42

1.2

58.89

61.44

u/l

0.12

286

Benign neoplasm: Tongue

2.59

4.41

1.2

52.72

50.67

u/l

0.08

COPD

257

1607

1.32

4.41

1.2

55.18

64.40

u/l

1.18

176

1053

Papillary adenocarcinoma of thyroid gland, excluding all cancers (controls excluding all cancers)

196

2.06

4.39

1.2

91.67

56.38

u/l

0.93

134

Open wound of wrist and hand

222

1638

1.35

4.39

1.2

67.62

66.93

u/l

0.04

131

1124

Disturbances of skin sensation

154

1081

1.43

4.38

1.3

1.2

48.40

60.07

u/l

3.24

117

713

Acute nephritic syndrome

2.92

4.35

1.1

56.92

66.41

u/l

0.27

Pleural plaque

273

1.88

4.35

1.1

1.2

54.57

68.37

u/l

0.79

167

Malignant melanoma

527

1.62

4.34

1.3

1.2

53.68

60.37

u/l

0.45

350

Amenorrhoea

170

2.13

4.34

1.3

1.2

76.96

65.00

u/l

0.29

109

Single spontaneous delivery

156

1174

0.70

4.32

1.2

59.57

58.03

u/l

0.14

108

803

Focal brain injury

177

2.10

4.32

1.2

96.24

65.89

u/l

0.63

113

Gonarthrosis, primary, with knee surgery

350

2264

1.27

4.30

1.1

1.2

55.34

62.08

u/l

1.17

221

1523

Dronedarone medication

2.81

4.30

1.3

1.2

59.73

61.07

u/l

0.04

Fenamates

424

1.58

4.29

1.1

1.2

47.52

63.60

u/l

2.33

295

Umbilical hernia

138

955

1.45

4.25

1.2

64.05

62.88

u/l

0.03

641

Malignant neoplasm of bladder

185

2.07

4.25

1.2

45.23

62.21

u/l

1.35

122

Non-small cell lung cancer, adenocarcinoma, excluding all cancers (controls excluding all cancers)

152

2.19

4.24

1.1

57.26

55.21

u/l

0.06

101

Malignant neoplasm of mesothelium and soft tissue, excluding all cancers (controls excluding all cancers)

172

2.11

4.23

1.1

60.12

56.20

u/l

0.19

114

Benign neoplasm of breast

431

1.68

4.23

1.2

56.63

59.58

u/l

0.18

291

Arterial embolism and thrombosis of lower extremity artery

2.58

4.22

1.1

1.2

75.88

51.18

u/l

0.62

Eating disorder

192

2.04

4.21

1.4

1.2

73.42

85.00

u/l

0.19

128

Malignant neoplasm of bronchus and lung, excluding all cancers (controls excluding all cancers)

103

558

1.55

4.21

1.2

64.41

55.86

u/l

0.50

353

Other extrapyramidal and movement disorders in other diseases

129

884

1.47

4.20

1.2

60.27

64.54

u/l

0.34

590

Mental and behavioural disorders due to sedatives or hypnotics

200

2.01

4.17

1.1

1.2

64.23

56.21

u/l

0.31

141

Allergic asthma (mode)

119

788

1.49

4.17

1.2

1.1

64.08

67.54

u/l

0.23

513

Other secondary coxarthrosis

109

2.42

4.16

1.1

1.2

60.72

52.58

u/l

0.33

therapeutic use

2.62

4.16

1.5

1.1

67.50

56.88

u/l

—

TMD related pain

2.55

4.14

1.2

68.93

54.00

u/l

0.36

Aortic valve malfunction, age under 60 years

307

1.80

4.13

1.2

61.90

63.48

u/l

0.05

206

Speech therapy

162

1161

1.40

4.13

1.2

64.05

62.57

u/l

0.07

138

762

Fall on and from stairs and steps

144

1011

1.43

4.12

1.2

55.90

67.92

u/l

1.26

667

Other and unspecified myopathies

257

1.88

4.12

1.3

1.1

71.97

70.31

u/l

0.03

176

Other symptoms and signs involving the digestive system and abdomen

637

1.55

4.11

1.2

75.93

63.98

u/l

0.43

430

Benign neoplasm of eye and adnexa

337

1.76

4.11

1.1

1.2

62.05

64.60

u/l

0.08

234

Haemorrhoids and perianal venous thrombosis

158

1128

1.40

4.10

1.2

57.00

64.32

u/l

1.10

756

Benign neoplasm: Kidney

2.73

4.10

1.2

36.67

55.21

u/l

2.79

Recurring oral aphthae, including avohilmo

481

1.63

4.09

1.2

71.53

68.38

u/l

0.09

328

Hypertrophic disorders of skin

148

2.18

4.09

1.0

1.1

55.83

60.31

u/l

0.17

106

Inflammatory diseases of female pelvic organs

378

2289

1.25

4.08

1.2

57.83

59.13

u/l

0.20

237

1579

Spirochaetal infections, other/unspecified

294

1.82

4.08

1.2

47.45

53.26

u/l

0.79

201

Hyperaldosteronism

2.59

4.07

1.2

50.50

53.03

u/l

0.11

Other and specified injuries of hip and thigh

3.23

4.07

1.3

1.1

67.60

60.60

u/l

—

Special screening examination for infectious and parasitic diseases

105

514

1.53

4.07

1.2

1.1

79.43

74.42

u/l

0.10

361

Other chronic obstructive pulmonary disease

245

1554

1.31

4.06

1.2

55.69

64.93

u/l

1.10

166

1017

COPD, hospital admission 2, with asthma infections

173

1069

1.38

4.05

1.2

56.49

62.31

u/l

0.56

126

706

Non-small cell lung cancer, excluding all cancers (controls excluding all cancers)

432

1.64

4.04

1.1

1.2

61.44

56.74

u/l

0.27

274

Malignant neoplasm of urinary organs

302

1.80

4.04

1.2

71.53

58.73

u/l

0.31

209

Melanocytic naevi, other sites/unspecified

196

2.00

4.02

1.3

1.1

65.27

58.44

u/l

0.24

135

N06DA Anticholinesterases

1017

0.63

4.00

1.1

1.2

62.96

60.84

u/l

0.12

680

Use of anticholinesterases

1017

0.63

4.00

1.1

1.2

62.96

60.84

u/l

0.12

680

All dysplastic lesions of the vulva

143

2.19

4.00

1.2

50.24

66.43

u/l

0.74

Pain in thoracic spine

578

1.56

4.00

1.2

108.75

63.12

u/l

0.45

377

Thoracic aortic aneurysm

431

1.66

3.98

1.2

49.71

65.67

u/l

1.40

287

Other and unspecified injuries of lower leg

211

1.96

3.96

1.3

1.2

56.64

57.61

u/l

0.05

151

Hypertrophic scar

137

2.21

3.96

1.0

1.1

55.83

60.04

u/l

0.16

Superficial injury of ankle and foot

341

1.74

3.95

1.3

1.1

64.74

73.26

u/l

0.38

241

Infective dermatitis

356

1.72

3.95

1.1

1.2

65.97

58.81

u/l

0.13

238

Other blood glucose lowering drugs, excl. Insulins

100

660

1.52

3.94

1.1

1.2

54.74

63.00

u/l

0.90

443

Myocardial infarction, unclassifiable

114

687

1.48

3.94

1.2

96.33

61.62

u/l

0.33

460

Personal history of other diseases and conditions

274

1.82

3.94

1.2

1.1

56.64

79.12

u/l

1.79

189

Corneal ulcer

100

660

1.52

3.93

1.4

1.2

62.30

61.06

u/l

0.07

446

Other benign neoplasms of skin

182

1315

1.36

3.93

1.3

1.2

60.40

57.98

u/l

0.21

112

847

Fitting and adjustment of other devices

179

1222

1.37

3.93

1.2

62.36

60.23

u/l

0.15

786

Follicular cysts of skin and subcutaneous tissue

101

669

1.52

3.91

1.2

69.16

60.95

u/l

0.31

454

Actinic keratosis

214

1534

1.33

3.91

1.2

59.74

59.73

u/l

0.00

136

1017

Enthesopathies of lower limb, excluding foot

132

923

1.44

3.89

1.3

1.2

57.33

61.95

u/l

0.31

609

Left ventricular outflow tract obstruction (LVOTO), broad definition

328

1.75

3.89

1.2

141.07

66.63

u/l

0.45

224

Delivery

161

1174

0.72

3.87

1.2

59.40

58.03

u/l

0.13

112

803

Malignant neoplasm of stomach

145

2.16

3.87

1.2

52.35

52.73

u/l

0.02

Skin changes due to chronic exposure to nonionizing radiation

219

1572

1.32

3.87

1.2

64.33

59.80

u/l

0.32

139

1041

Angina pectoris

347

1874

1.25

3.87

1.2

57.43

61.46

u/l

0.65

259

1239

Suppurative and unspecified otitis media

169

1091

1.38

3.87

1.3

1.2

81.41

69.52

u/l

0.63

118

755

Spontaneous rupture of synovium and tendon

270

1.83

3.86

1.1

1.2

64.39

56.67

u/l

0.44

186

Superficial injury of wrist and hand

655

1.52

3.85

1.1

1.2

65.38

64.09

u/l

0.05

453

Carcinoma in situ of breast, intraductal

382

1.69

3.85

1.2

62.68

58.51

u/l

0.22

263

Erythema intertrigo

2.72

3.84

1.3

1.2

54.38

51.26

u/l

0.16

Other noninflammatory disorders of vulva and perineum

337

1.73

3.83

1.2

48.57

61.81

u/l

1.23

227

Other specified and unspecified retinal disorders

101

2.40

3.83

1.2

61.73

52.40

u/l

0.43

Benign neoplasm: Duodenum

2.64

3.83

1.2

56.86

52.28

u/l

0.22

Intrahepatic Cholestasis of Pregnancy (ICP) , incl. ICD-8, excluding more controls

264

1.83

3.81

1.3

1.2

47.05

59.09

u/l

0.98

179

Other enthesopathy of foot (+metatarsalgia)

368

1.69

3.80

1.3

1.2

62.88

60.72

u/l

0.07

252

Macular hole

187

2.00

3.79

1.2

45.96

55.02

u/l

1.17

136

Intrahepatic Cholestasis of Pregnancy (ICP) , excluding more controls

180

2.01

3.78

1.3

1.2

50.34

64.73

u/l

0.81

122

Ulcer of oesophagus

187

1.99

3.78

1.1

1.2

60.16

57.29

u/l

0.09

140

Polyp of the female genital tract

218

956

1.33

3.77

1.2

64.84

58.09

u/l

0.99

135

650

Other disorders of bone density and structure

2.76

3.77

1.2

1.1

58.92

52.26

u/l

0.20

Striking against or struck by other objects

157

1138

1.38

3.76

1.2

86.17

69.19

u/l

0.22

103

766

Hereditary corneal dystrophies

102

2.38

3.76

1.1

1.2

50.82

50.75

u/l

0.00

Subjective visual disturbances

138

980

1.41

3.75

1.2

53.04

63.59

u/l

1.48

101

650

Colorectal adenocarcinoma, excluding all cancers (controls excluding all cancers)

595

1.53

3.75

1.1

1.2

96.19

58.12

u/l

0.89

380

Localized swelling, mass and lump of skin and subcutaneous tissue

177

1310

1.36

3.74

1.2

55.52

66.76

u/l

1.25

122

866

Alcohol-induced acute pancreatitis

2.42

3.74

1.0

1.2

63.64

57.59

u/l

0.19

Mental disorders, not otherwise specified

230

1.88

3.73

1.3

1.2

51.00

63.28

u/l

0.72

154

Papillary adenocarcinoma of thyroid gland

168

2.04

3.70

1.2

88.61

55.26

u/l

0.75

120

Hemiplegia

148

2.11

3.69

1.2

52.50

57.64

u/l

0.18

106

Synovial cyst of popliteal space [Baker]

231

1.87

3.69

1.4

1.2

65.14

56.73

u/l

0.52

161

Other congenital malformations of skin

122

2.23

3.68

1.1

1.2

59.06

62.32

u/l

0.09

Right bundle-branch block

2.49

3.64

1.1

1.2

56.30

60.69

u/l

—

Dermatographic urticaria

197

1.94

3.63

1.3

1.1

58.96

63.59

u/l

0.16

138

Diseases of vocal cords and larynx+other diseases of upper respiratory tract, no elsewhere classified

286

2222

1.26

3.61

1.2

57.25

63.90

u/l

1.31

183

1499

Clear cell adenocarcinoma of kidney, excluding all cancers (controls excluding all cancers)

104

2.33

3.60

1.2

51.38

49.73

u/l

0.07

Metatarsalgia

336

1.71

3.60

1.3

1.2

64.29

62.02

u/l

0.07

233

Malignant neoplasm of oral cavity, excluding all cancers (controls excluding all cancers)

104

2.33

3.60

1.3

1.2

44.07

52.79

u/l

0.59

Acute pharyngitis

387

1.65

3.57

1.3

1.2

140.17

76.16

u/l

0.44

268

Dislocation, sprain and strain of joints and ligaments at wrist and hand level

148

1074

1.38

3.56

1.2

69.84

63.26

u/l

0.42

736

Early complications of trauma

124

2.20

3.55

1.1

1.2

69.24

58.31

u/l

0.29

!Aliquae complicationes praecoces traumatis

124

2.20

3.55

1.1

1.2

69.24

58.31

u/l

0.29

Other and unspecified trigeminal disorders

3.09

3.55

1.2

1.3

55.88

54.33

u/l

—

Special screening examination for neoplasms

124

2.19

3.55

1.7

1.1

55.57

59.59

u/l

0.12

Superficial injury of thorax

484

1.58

3.55

1.2

60.90

58.07

u/l

0.16

318

Carcinoma in situ of skin of lower limb, including hip

2.85

3.54

1.3

1.2

52.18

49.68

u/l

0.09

Pyoderma

3.08

3.54

1.4

1.1

50.63

127.74

u/l

—

Allergic urticaria

256

1.81

3.54

1.2

42.77

82.16

u/l

2.12

183

Background retinopathy and retinal vascular changes

2.85

3.54

1.4

1.2

64.60

52.90

u/l

—

Carcinoma in situ of skin

242

1.83

3.52

1.1

1.2

51.73

58.88

u/l

0.35

164

Seborrhoeic keratosis

124

875

1.42

3.52

1.3

1.2

64.72

63.06

u/l

0.09

571

Other misadventures during surgical and medical care

2.74

3.51

1.1

68.58

55.19

u/l

0.34

Carcinoma in situ of skin of upper limb, including shoulder

3.21

3.51

1.4

1.2

87.38

49.04

u/l

—

Unstable angina pectoris

206

1302

1.31

3.49

1.2

54.41

63.30

u/l

1.31

147

835

Polycystic ovarian syndrome, consortium definition

443

2215

1.21

3.49

1.2

58.86

59.03

u/l

0.02

291

1528

Benign neoplasm: Anus and anal canal

2.44

3.48

1.2

63.57

53.77

u/l

0.35

Adhesive capsulitis of shoulder

102

696

1.47

3.47

1.2

50.38

65.11

u/l

2.59

456

Basal cell carcinoma, including avohilmo

330

2101

1.24

3.46

1.2

60.46

61.94

u/l

0.14

223

1384

Other behavioural and emotional disorders with onset usually occurring in childhood and adolescence

117

2.20

3.46

1.3

1.1

142.00

182.02

u/l

0.25

Sacroiliitis, not elsewhere classified

119

2.20

3.45

1.3

1.2

47.74

68.15

u/l

0.67

Oter anti-inflammatory and antirheumatic agents, non-steroids

136

535

1.41

3.42

1.2

60.27

64.14

u/l

0.22

367

Agoraphobia

2.78

3.42

1.4

1.2

67.25

45.62

u/l

—

Benign neoplasm: Skin of scalp and neck

3.01

3.42

1.1

1.2

58.43

52.59

u/l

—

Other peripheral vascular diseases

245

1.81

3.40

1.1

1.2

55.84

54.86

u/l

0.08

173

Keratitis and keratoconjunctivitis in other diseases classified elsewhere

107

2.27

3.40

1.2

52.00

51.78

u/l

0.01

Ganglion

120

848

1.42

3.39

1.1

1.2

61.57

60.47

u/l

0.07

570

Malignant neoplasm of mesothelium and soft tissue

120

2.19

3.39

1.2

62.84

52.94

u/l

0.46

Ovarian dysfunction

167

1.99

3.38

1.2

1.1

54.61

62.46

u/l

0.30

112

Recurring oral aphthae

140

2.09

3.38

1.3

1.2

88.91

63.48

u/l

0.48

Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care

253

1.79

3.37

1.3

1.2

43.53

57.61

u/l

1.71

175

Lichen simplex chronicus

101

2.30

3.37

1.3

1.1

49.00

54.26

u/l

0.38

Alzheimer disease

837

0.65

3.36

1.1

1.2

54.93

60.52

u/l

0.38

561

224

1.84

3.36

1.1

1.2

53.69

60.21

u/l

0.37

152

Biomechanical lesions, not elsewhere classified

154

2.03

3.36

1.3

1.2

62.91

54.56

u/l

0.64

110

Vulvovaginal ulceration/inflammation in other diseases

154

2.03

3.35

1.1

1.2

52.12

64.36

u/l

0.59

106

Palmar fascial fibromatosis [Dupuytren]

539

1.53

3.35

1.2

50.28

67.47

u/l

1.82

348

Basal cell carcinoma

320

2064

1.24

3.34

1.2

60.77

62.03

u/l

0.11

216

1357

Diseases of tongue

189

1.92

3.34

1.3

1.2

72.92

54.58

u/l

0.78

120

Other and unspecified follicular disorders

121

2.17

3.33

1.2

60.50

54.34

u/l

0.25

Certain conditions originating in the perinatal period

179

1.89

3.32

1.4

1.1

71.38

151.68

u/l

1.75

127

Open wound of forearm

247

1.79

3.31

1.1

98.81

59.50

u/l

0.83

168

Other surgical follow-up care

2.56

3.30

1.3

1.2

64.67

58.86

u/l

0.12

Dental caries 2

431

2827

1.20

3.30

1.2

79.66

65.30

u/l

0.58

289

1915

Conjunctivitis (acute, non atopic)

143

1043

1.37

3.30

1.2

55.60

67.11

u/l

1.49

105

704

Other chronic obstructive pulmonary disease, including avohilmo

297

1989

1.24

3.28

1.2

55.29

62.79

u/l

1.08

200

1322

Maternal care for other conditions predominantly related to pregnancy

110

760

1.43

3.28

1.2

52.91

59.62

u/l

0.89

502

Malignant neoplasm of skin

359

2218

1.22

3.27

1.2

57.86

62.63

u/l

0.63

238

1467

Postmenopausal bleeding

207

870

1.31

3.26

1.2

58.13

59.06

u/l

0.10

129

599

Amputation of thigh

2.80

3.26

1.5

1.1

56.43

50.76

u/l

—

Intrahepatic Cholestasis of Pregnancy (ICP)

191

1.90

3.24

1.3

1.2

50.34

63.53

u/l

0.73

127

Appendectomy

366

2910

1.21

3.24

1.2

56.64

64.21

u/l

1.47

264

1942

Pain associated with micturition

393

1.61

3.24

1.3

1.1

65.74

70.56

u/l

0.16

275

Other and unspecified vascular occlusions

294

1.71

3.22

1.2

66.92

59.31

u/l

0.46

202

Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis

330

2197

1.23

3.22

1.2

66.06

59.82

u/l

0.56

239

1466

Urethral stricture

136

2.07

3.22

1.1

1.3

91.17

67.15

u/l

0.66

Other disorders of bladder

355

1.64

3.22

1.2

59.28

67.23

u/l

0.31

222

Ovarian cyst

230

1035

1.29

3.21

1.2

55.67

59.19

u/l

0.38

159

712

Alcohol abuse, main dg, excluding more controls

425

1.58

3.21

1.1

1.2

58.17

58.55

u/l

0.02

291

Erythema nodosum

2.29

3.21

1.0

1.2

44.00

57.20

u/l

1.44

Malignant melanoma of skin

371

1.63

3.20

1.3

1.2

49.61

59.64

u/l

0.60

249

Melanocytic naevi of upper limb, including shoulder

2.89

3.20

1.2

1.1

55.00

63.84

u/l

—

Alcohol dependence

134

976

1.38

3.20

1.1

1.2

73.47

64.48

u/l

0.24

646

COPD related to multimorbidity

210

1371

1.29

3.19

1.1

1.2

55.51

62.18

u/l

0.79

143

887

Intrahepatic Cholestasis of Pregnancy (ICP) , incl. ICD-8

280

1.72

3.19

1.3

1.2

47.05

59.71

u/l

1.13

195

Single delivery by forceps and vacuum extractor

365

0.53

3.18

1.2

1.3

65.55

58.84

u/l

0.33

258

Rotator cuff syndrome

350

2135

1.22

3.17

1.2

55.49

64.60

u/l

1.57

234

1425

Disorders of optic nerve, not elsewhere classified

2.76

3.17

1.2

64.78

54.84

u/l

—

Other abnormal immunological findings in serum

2.76

3.17

1.1

60.60

89.57

u/l

—

Other hammer toe(s) (acquired)

104

680

1.44

3.17

1.1

1.2

53.89

60.76

u/l

0.56

445

Other disorders of breast

531

1.51

3.15

1.2

54.40

61.14

u/l

0.70

367

Other encephalitis

2.43

3.15

1.1

1.2

54.83

61.40

u/l

0.16

Melanocytic naevi of scalp and neck

2.57

3.14

1.5

1.2

59.17

53.19

u/l

0.16

Hyperkinetic disorders, excluding more controls

167

1.93

3.14

1.3

1.2

105.44

85.41

u/l

0.31

115

Nummular dermatitis

237

1.78

3.13

1.5

1.1

80.00

63.40

u/l

0.29

159

Varicella [chickenpox]

131

2.08

3.13

1.3

1.2

56.86

70.66

u/l

0.53

Other disorders of conjunctiva

516

1.52

3.12

1.2

56.63

59.09

u/l

0.12

347

Other diseases of peritoneum

138

2.05

3.12

1.1

1.2

52.17

53.75

u/l

0.07

Diplopia

421

1.57

3.11

1.3

1.2

46.93

60.92

u/l

2.02

284

COPD, hospital admissions

244

1638

1.26

3.10

1.2

55.69

63.95

u/l

0.96

166

1067

Atopic dermatitis, strict definition

142

1028

1.36

3.10

1.2

75.28

73.26

u/l

0.07

713

Carcinoma in situ of other and unspecified genital organs

3.12

3.10

1.1

1.2

58.57

58.50

u/l

—

107

713

1.43

3.10

1.2

1.1

63.23

61.94

u/l

0.04

479

Pilonidal cyst

223

1.80

3.10

1.0

1.1

63.10

56.98

u/l

0.36

153

Dental caries 2 and operation codes

420

2800

1.19

3.07

1.2

80.52

65.35

u/l

0.60

279

1903

Malignant neoplasm of other connective and soft tissue

2.53

3.05

1.2

55.33

51.45

u/l

0.16

Congenital malformations of genital organs

267

1.72

3.05

1.2

177.21

71.86

u/l

0.52

188

Anogenital herpesviral [herpes simplex] infection

153

1.97

3.04

1.1

1.2

47.37

63.43

u/l

0.83

108

Transient ischemic attack

293

1972

1.23

3.03

1.1

1.2

54.91

64.37

u/l

1.67

199

1312

Supplementary factors related to causes of morbidity and mortality classified elsewhere

156

1175

1.33

3.02

1.2

73.00

64.54

u/l

0.72

106

786

Memory loss

300

1.68

3.02

1.2

60.49

58.93

u/l

0.04

199

Bullous pemphigoid

2.78

3.00

1.2

82.75

49.74

u/l

—

Dissection of aorta

2.37

2.99

1.3

1.2

58.23

47.09

u/l

0.31

Superficial injury of shoulder and upper arm

347

1.62

2.99

1.2

74.32

61.07

u/l

0.46

234

Somnolence, stupor and coma

134

2.03

2.96

1.2

45.78

55.50

u/l

0.89

Ocular pain

249

1.74

2.95

1.3

1.2

46.88

61.34

u/l

2.45

174

Event of undetermined intent

169

1.91

2.95

1.1

1.2

43.61

58.17

u/l

1.16

120

Allergic purpura

2.29

2.94

1.4

1.2

73.58

61.81

u/l

0.30

Disorders of muscles

310

1.65

2.94

1.2

83.97

62.53

u/l

0.65

201

Cervicalgia

117

848

1.38

2.92

1.2

58.71

63.63

u/l

0.40

541

COPD, early/later onset

245

1655

1.25

2.92

1.2

55.69

64.04

u/l

0.99

166

1081

Benign neoplasm of middle ear and respiratory system

206

1.81

2.90

1.2

55.11

58.55

u/l

0.16

136

Mixed hyperlipidaemia

115

2.10

2.89

1.2

42.50

57.63

u/l

0.70

Osteopathy in diseases classified elsewhere

5.51

2.89

1.3

1.0

68.71

375.00

u/l

—

Pregnancy, childbirth and the puerperium

107

781

0.71

2.88

1.2

60.30

59.12

u/l

0.06

527

Eating disorders

258

1.71

2.88

1.2

67.57

75.06

u/l

0.15

175

Benign neoplasm: Rectosigmoid junction

122

2.07

2.88

1.2

53.20

50.68

u/l

0.12

Other acute skin changes due to ultraviolet radiation

102

2.18

2.87

1.1

1.2

85.75

53.68

u/l

0.35

Other disorders of eye and adnexa

478

1.51

2.87

1.3

1.2

51.25

69.83

u/l

1.47

329

Other and unspecified injuries of head

178

1.87

2.87

1.1

1.2

78.85

57.27

u/l

0.60

120

Melanocytic naevi of trunk

367

1.59

2.86

1.2

1.1

88.76

61.38

u/l

0.49

252

Other symptoms and signs involving the circulatory and respiratory systems

171

1.88

2.85

1.2

1.1

57.60

86.51

u/l

0.69

114

D07AA Corticosteroids, weak (group I)

486

1.51

2.85

1.2

88.15

72.31

u/l

0.26

333

Epilepsy

159

1209

1.31

2.84

1.2

66.12

75.16

u/l

0.50

111

820

Oxicams

137

574

1.36

2.84

1.1

1.2

66.04

64.11

u/l

0.08

398

Otitis media, unspecified

266

1.67

2.84

1.3

1.2

155.56

77.52

u/l

0.40

197

Later onset COPD, excluding more controls

530

1.43

2.84

1.2

55.22

74.65

u/l

0.96

327

Foreign body in ear

2.80

2.83

1.3

1.2

54.75

68.00

u/l

—

Malignant neoplasm of pancreas, excluding all cancers (controls excluding all cancers)

208

1.79

2.82

1.1

50.03

56.37

u/l

0.58

134

Cervicocranial syndrome

400

1.56

2.82

1.3

1.2

60.02

62.90

u/l

0.16

257

Other/unspecified enthesopathies of lower limb, excluding foot

238

1.73

2.81

1.1

1.2

69.88

62.73

u/l

0.17

157

Retinal haemorrhage

2.49

2.80

1.1

1.2

121.89

65.40

u/l

—

Other and unspecified visual disturbances

299

1.65

2.80

1.1

1.2

60.16

56.47

u/l

0.16

205

Pemphigoid

2.49

2.80

1.2

76.89

51.42

u/l

—

Chondropathies

530

1.48

2.78

1.2

1.1

69.07

55.54

u/l

1.05

371

Ankylosing hyperostosis [Forestier]

2.91

2.77

1.0

1.3

57.67

48.15

u/l

—

Pneumonitis due to solids and liquids

217

1.76

2.76

1.1

55.43

54.22

u/l

0.05

144

Disorders of eyelid in diseases classified elsewhere

104

2.14

2.75

1.0

1.3

66.40

51.45

u/l

0.55

Benign neoplasm of urinary organs

138

1.97

2.75

1.2

36.53

54.91

u/l

3.90

100

Car occupant injured in noncollision transport accident

104

2.13

2.75

1.2

68.00

50.70

u/l

0.77

Non-small cell lung cancer, adenocarcinoma, helper endpoint

181

1.84

2.74

1.1

57.26

59.80

u/l

0.08

126

Non-small cell lung cancer, adenocarcinoma

181

1.84

2.74

1.1

57.26

59.80

u/l

0.08

126

Laparoscopic right hemicolectomy

167

1.87

2.72

1.1

1.2

102.75

51.38

u/l

1.01

118

Radiculopathy

658

1.42

2.70

1.1

1.2

53.45

65.87

u/l

1.32

427

Cluster headache, strict

105

2.11

2.69

1.3

1.1

52.94

57.96

u/l

0.43

Benign neoplasm: Choroid

197

1.79

2.68

1.1

1.2

63.67

53.73

u/l

0.47

143

Dementia

138

1257

0.76

2.68

1.1

1.2

60.96

61.07

u/l

0.01

825

Traumatic subarachnoid haemorrhage

2.19

2.68

1.3

1.1

121.53

62.52

u/l

0.83

Other viral infections characterized by skin and mucous membrane lesions, not elsewhere classified

2.19

2.67

1.3

1.2

110.23

121.28

u/l

0.07

Malignant neoplasm of thyroid gland

242

1.71

2.67

1.1

1.2

85.30

54.32

u/l

0.75

170

Malignant neoplasm of rectum, excluding all cancers (controls excluding all cancers)

350

1.58

2.66

1.3

1.2

83.38

57.84

u/l

0.39

226

Combined immunodeficiencies

3.18

2.66

1.3

1.2

67.20

58.04

u/l

—

DVT of lower extremities

101

727

1.39

2.66

1.2

60.90

65.21

u/l

0.26

472

Herpesviral [herpes simplex] infections

374

1.56

2.66

1.1

1.2

55.23

59.25

u/l

0.24

257

Encephalitis

2.23

2.65

1.1

1.2

54.83

62.51

u/l

0.19

Spondylolisthesis/Spondylolysis

107

779

1.38

2.64

1.3

1.2

56.27

63.95

u/l

0.81

506

Speech disturbances, not elsewhere classified

258

1.68

2.64

1.0

1.2

60.61

55.12

u/l

0.27

177

Wet age-related macular degeneration

567

1.44

2.64

1.2

74.43

62.07

u/l

0.54

380

Assault

367

1.56

2.63

1.3

1.2

71.14

59.34

u/l

0.56

258

Acute and transient psychotic disorders

399

1.54

2.63

1.1

1.2

69.98

60.06

u/l

0.35

279

Pneumococcal septicemia

2.17

2.61

1.5

1.2

108.60

57.09

u/l

0.40

Acromegaly and pituitary gigantism

4.77

2.61

1.3

54.29

66.89

u/l

—

Status epilepticus

100

2.12

2.59

1.1

51.33

64.22

u/l

0.54

Plantar fascial fibromatosis

369

1.55

2.58

1.2

58.58

60.60

u/l

0.12

257

Oligomenorrhoea

2.20

2.57

1.3

1.2

49.18

71.61

u/l

0.63

Other congenital malformations of the digestive system

120

2.00

2.57

1.6

1.2

43.79

117.95

u/l

1.80

Moderate visual impairment, binocular

2.37

2.56

1.4

1.2

86.00

61.93

u/l

—

Malignant neoplasm of colon

516

1.46

2.55

1.1

1.2

91.89

59.96

u/l

0.97

342

Benign neoplasm: Long bones of lower limb

2.24

2.54

1.1

1.2

57.37

56.85

u/l

—

Use of donepezil

616

0.61

2.54

1.1

1.2

53.57

62.01

u/l

0.80

407

Nonischemic cardiomyopathy

157

1.86

2.52

1.1

1.2

211.19

64.77

u/l

0.65

106

Benign paroxysmal vertigo

164

1280

1.29

2.52

1.2

59.52

61.89

u/l

0.21

106

862

Lupus erythematosus

2.29

2.52

1.2

1.1

65.73

51.55

u/l

0.60

Use of memantine

748

0.66

2.52

1.1

1.2

53.08

60.37

u/l

0.63

495

Use of other anti-dementia drugs

748

0.66

2.52

1.1

1.2

53.08

60.37

u/l

0.63

495

Alzheimer disease, including avohilmo

979

0.73

2.52

1.1

1.2

58.95

60.85

u/l

0.13

654

Sequelae of injuries of lower limb

316

1.59

2.52

1.2

56.67

55.81

u/l

0.05

216

Acne

231

1.69

2.51

1.5

1.2

72.68

69.90

u/l

0.09

153

Other bursopathies

485

1.47

2.51

1.4

1.2

59.64

64.60

u/l

0.36

319

Abnormal spermatozoa

348

1.56

2.50

1.1

1.2

87.08

67.13

u/l

0.47

218

Disorders of optic nerve and visual pathways

293

1.61

2.50

1.2

1.1

58.32

63.48

u/l

0.16

203

Cerebral cysts

151

1.87

2.47

1.1

1.2

82.43

57.71

u/l

0.76

110

Excessive, frequent and irregular menstruation

234

1052

1.24

2.46

1.2

55.42

59.85

u/l

0.62

159

723

Other predominantly sexually transmitted diseases, not elsewhere classified

553

1.43

2.46

1.2

75.51

58.00

u/l

0.84

385

Burns and corrosions

422

1.50

2.45

1.2

66.51

67.97

u/l

0.05

288

Acute gastritis

218

1.71

2.44

1.2

62.50

57.54

u/l

0.29

153

Acute laryngitis and tracheitis

298

1.59

2.43

1.1

61.50

86.25

u/l

1.31

203

Follicular lymphoma, hilmo

138

1.90

2.42

1.2

48.53

57.62

u/l

0.69

102

Sequelae of injuries, of poisoning and of other consequences of external causes

121

912

1.33

2.41

1.2

61.94

62.10

u/l

0.01

614

Cleft lip and palate

5.10

2.41

1.3

1.2

59.67

116.14

u/l

—

Hypertrophy of breast

104

767

1.36

2.40

1.1

1.2

53.39

58.56

u/l

0.76

525

Other malignant neoplasms of skin (=non-melanoma skin cancer)

301

1986

1.20

2.40

1.2

59.37

62.61

u/l

0.34

201

1312

Degeneration of the brain due to alcohol

2.37

2.40

1.2

81.67

49.64

u/l

—

Degeneration of nervous system due to alcohol

2.37

2.40

1.2

1.3

81.67

49.77

u/l

—

Unspecified lump in breast

708

1.38

2.39

1.2

58.05

60.06

u/l

0.18

485

Alzheimer’s disease (Late onset)

614

0.64

2.39

1.1

1.2

51.27

61.07

u/l

0.70

411

Melanocytic naevi, other sites/unspecified

235

1.67

2.38

1.3

1.2

65.27

57.38

u/l

0.29

167

Degenerative diseases of the nervous system

984

0.73

2.38

1.1

1.2

60.50

61.53

u/l

0.06

651

Benign neoplasm: Ill-defined sites within the digestive system

4.22

2.38

1.4

1.2

59.29

57.42

u/l

—

Cleft lip and cleft lip and palate

4.19

2.37

1.3

60.29

101.90

u/l

—

Autoimmune thyroiditis

2.53

2.37

1.1

1.2

56.43

59.68

u/l

—

Hypertrophy of breast in women and men

114

855

1.34

2.36

1.1

1.2

56.04

59.09

u/l

0.31

585

Gluteal tendinitis

125

1.94

2.36

1.5

1.2

51.13

55.94

u/l

0.32

Abnormal blood-pressure reading, without diagnosis

111

1.99

2.36

1.0

1.2

65.92

64.97

u/l

0.02

Congenital malformations of ovaries, fallopian tubes and broad ligaments

161

1.81

2.35

1.1

44.17

64.14

u/l

1.20

107

Abdominal aortic aneurysm (AAA)

265

1.61

2.33

1.2

41.07

61.24

u/l

1.83

169

Coxibs

154

634

1.30

2.33

1.1

1.2

54.85

68.92

u/l

2.26

109

450

Haemangioma and lymphangioma, any site

252

1.63

2.33

1.2

1.1

53.94

69.80

u/l

1.12

169

Other and unspecified mononeuropathies, also in other diseases

2.06

2.32

1.2

55.42

51.43

u/l

0.20

Toxic effect of ethanol

112

1.98

2.31

1.1

1.2

82.09

58.73

u/l

0.43

Benign neoplasm: Skin of lower limb, including hip

2.39

2.30

1.5

1.2

70.50

57.79

u/l

—

Malignant neoplasm of anus and anal canal

4.75

2.29

2.2

1.3

58.83

52.50

u/l

—

Erectile dysfunction

238

1.65

2.29

1.2

87.97

62.26

u/l

0.55

155

Right hemicolectomy

185

1.74

2.28

1.2

86.55

52.37

u/l

0.49

128

Colon adenocarcinoma

397

1.49

2.28

1.1

1.2

88.61

57.97

u/l

0.81

266

Other and unspecified rosacea

293

1.58

2.27

1.2

51.19

54.31

u/l

0.23

205

Thyroiditis

254

1.62

2.27

1.1

1.2

56.52

56.67

u/l

0.01

173

Burns and corrosions of external body surface, specified by site

301

1.57

2.27

1.2

68.84

62.87

u/l

0.20

214

Clear cell adenocarcinoma of kidney

127

1.90

2.26

1.2

51.38

53.43

u/l

0.09

Chondrocostal junction syndrome [Tietze]

120

1.93

2.26

1.2

62.78

51.14

u/l

0.82

Other and unspecified injuries of ankle and foot

113

1.96

2.25

1.3

1.1

76.53

65.96

u/l

0.11

Leisure time condition

614

1.39

2.25

1.2

76.98

63.97

u/l

0.68

414

Migraine

249

1753

1.21

2.25

1.2

55.07

63.99

u/l

1.76

179

1194

Leiomyoma of uterus

400

1953

1.17

2.25

1.2

59.10

57.77

u/l

0.23

262

1334

Malignant neoplasm of eye, brain and central nervous system, excluding all cancers (controls excluding all cancers)

186

1.73

2.24

1.2

59.83

74.12

u/l

0.34

127

Alzheimer’s disease, wide definition

690

0.68

2.24

1.1

1.2

54.49

60.78

u/l

0.46

469

Type of accident

139

1081

1.29

2.24

1.2

73.53

64.88

u/l

0.67

723

Sequelae of infectious and parasitic diseases

232

1.65

2.23

1.3

1.2

63.41

56.49

u/l

0.29

162

Chronic conjunctivitis

2.06

2.22

1.4

1.1

83.85

62.36

u/l

0.34

Meniscus derangement

298

1714

1.19

2.22

1.2

59.45

68.50

u/l

1.19

211

1134

Cardiac murmurs and other cardiac sounds

268

1.59

2.21

1.3

1.1

74.97

115.12

u/l

0.59

185

Benign neoplasm of mouth and pharynx

327

1.54

2.21

1.2

1.1

49.83

56.92

u/l

0.60

213

HSIL lesion of the vulva

2.44

2.21

1.2

1.1

39.13

55.03

u/l

—

Universal erythroderma, KELA reimbursement

2.65

2.19

1.2

1.1

44.50

53.88

u/l

—

Congenital malformations of cardiac septa

181

1.72

2.19

1.4

1.2

218.27

105.52

u/l

0.34

132

Other lesions of median nerve

2.09

2.18

1.1

1.2

75.08

50.13

u/l

0.72

Dementia, including avohilmo

157

1363

0.79

2.17

1.1

1.2

60.24

60.69

u/l

0.03

906

Disorders of psychological development

252

1.59

2.17

1.3

1.2

85.30

109.46

u/l

0.64

183

Radial styloid tenosynovitis [de Quervain]

173

1.74

2.17

1.1

1.2

55.43

63.63

u/l

0.34

118

Bronchitis, not specified as acute or chronic

265

1.59

2.17

1.4

1.2

54.96

57.26

u/l

0.11

183

Menorrhagia

220

993

1.23

2.16

1.2

57.42

58.23

u/l

0.09

149

676

Drug-induced systemic lupus erythematosus

3.76

2.16

1.3

38.29

53.91

u/l

—

Presbycusis

457

1.44

2.16

1.1

47.37

62.74

u/l

2.23

316

Other noninfective disorders of lymphatic vessels and lymph nodes

115

1.93

2.16

1.6

1.2

51.80

53.70

u/l

0.09

Premature rupture of membranes

568

0.67

2.16

1.2

59.06

58.26

u/l

0.05

396

Dementia in Alzheimer disease

483

0.62

2.16

1.0

1.1

52.06

61.92

u/l

0.47

314

Cluster headache, strict, including avohilmo

144

1.82

2.15

1.3

1.2

50.61

57.00

u/l

0.67

Other sleep disorders

378

1.49

2.15

1.2

1.1

63.00

67.77

u/l

0.15

253

Psychotic depression

174

1.73

2.13

1.1

1.2

52.90

53.11

u/l

0.01

123

Benign neoplasm: Kidney

102

1.98

2.11

1.2

36.67

51.75

u/l

2.20

False labour

770

0.74

2.10

1.1

1.2

54.48

56.84

u/l

0.28

534

Cramp and spasm

138

1.82

2.09

1.2

62.29

54.86

u/l

0.37

Congenital malformations of the circulatory system

424

1.44

2.08

1.3

1.2

159.19

86.04

u/l

0.44

296

Malignant neoplasm of head and neck, excluding all cancers (controls excluding all cancers)

260

1.58

2.08

1.2

1.1

67.89

59.66

u/l

0.16

167

Unspecified/other endometriosis

268

1.57

2.08

1.2

46.00

58.05

u/l

1.02

171

Otitis externa, unspecified

332

1.51

2.08

1.2

89.56

65.93

u/l

0.48

234

Acute alcohol intoxication, ICD10

632

1.36

2.08

1.1

1.2

64.20

60.19

u/l

0.21

424

Diseases of middle ear and mastoid

276

1905

1.19

2.07

1.2

71.64

68.40

u/l

0.21

190

1277

Injuries to the neck

104

787

1.32

2.07

1.2

55.65

61.16

u/l

0.59

527

Impetigo

110

1.92

2.06

1.4

1.1

105.19

92.19

u/l

0.11

Toxic effects of substances chiefly nonmedicinal as to source

333

1.51

2.05

1.1

1.2

62.39

60.20

u/l

0.08

230

Contact with sharp glass

103

1.95

2.05

1.1

1.2

74.91

54.62

u/l

0.79

Benign neoplasm of breast

515

1.40

2.05

1.2

56.63

59.30

u/l

0.17

349

Pollen allergy

568

1.38

2.04

1.2

75.58

72.22

u/l

0.05

402

Heartburn

310

1.52

2.02

1.2

53.62

67.49

u/l

1.13

218

Other and unspecified glaucoma

223

1.62

2.02

1.3

1.2

75.08

55.12

u/l

0.61

148

Speech and linguistic disorders, excluding more controls

152

1.74

2.02

1.2

81.44

113.07

u/l

0.63

112

Cluster headache, wide

118

1.88

2.02

1.3

1.1

52.94

56.94

u/l

0.34

Mixed conductive and sensorineural hearing loss

450

1.43

2.01

1.2

50.30

61.41

u/l

1.42

304

Unspecified mental disorder

211

1744

1.21

2.01

1.1

1.2

57.51

61.69

u/l

0.45

146

1180

Adult respiratory distress syndrome

2.85

2.01

1.1

1.2

74.33

69.36

u/l

—

Acetic acid derivatives and related substances

152

625

1.27

2.01

1.1

1.2

59.36

68.50

u/l

0.68

105

443

Unspecified event, undetermined intent

2.16

1.99

1.0

1.2

41.22

49.34

u/l

—

Benign neoplasm: Ill-defined sites within the digestive system

3.41

1.98

1.4

1.1

59.29

59.00

u/l

—

Dislocation, sprain and strain of joints and ligaments at ankle and foot level

174

1411

1.23

1.98

1.2

50.43

67.73

u/l

4.33

115

953

Disorders of vestibular function (Vertigo)

258

2164

1.19

1.96

1.2

57.00

61.29

u/l

0.62

162

1442

Other specified/unspecified dorsopathies

105

1.92

1.96

1.0

1.2

69.73

52.65

u/l

0.31

Superficial injury of forearm

257

1.56

1.94

1.2

75.91

59.88

u/l

0.26

179

Acute otitis externa, noninfective

2.47

1.94

1.3

1.2

50.33

52.00

u/l

—

Glaucoma-related operations

172

1.70

1.93

1.1

1.2

44.38

55.84

u/l

1.21

122

Diseases of inner ear

300

2515

1.17

1.93

1.2

56.74

61.10

u/l

0.73

190

1685

Donors of organs and tissues

2.60

1.93

1.1

1.3

44.60

50.64

u/l

—

Crushed, pushed or stepped on by crowd or human stampede

195

1.65

1.93

1.1

1.2

48.25

66.08

u/l

1.35

138

Non-small cell lung cancer

547

1.38

1.92

1.1

1.2

61.44

64.04

u/l

0.12

367

Any dementia

122

1095

0.78

1.92

1.1

1.2

62.37

60.59

u/l

0.10

724

Coxarthrosis, primary

335

2511

1.16

1.91

1.2

59.49

62.11

u/l

0.24

217

1679

Spinal instabilities

1.94

1.91

1.0

1.2

62.62

51.67

u/l

0.57

Intracerebral haemorrhage

397

1.44

1.90

1.3

1.2

63.93

63.04

u/l

0.03

272

Benign neoplasm of middle ear and respiratory system

235

1.58

1.90

1.2

55.11

57.44

u/l

0.11

159

Urticaria due to cold and heat

3.23

1.89

1.0

1.2

33.29

69.83

u/l

—

Benign neoplasm of bone and articular cartilage

220

1.60

1.87

1.2

1.1

68.10

62.30

u/l

0.19

152

Disorders of puberty, all

2.88

1.86

1.4

1.0

190.38

147.40

u/l

—

LSIL lesion of the cervix uteri, vagina or vulva

491

1.39

1.86

1.1

1.2

57.06

57.31

u/l

0.01

326

Other and unspecified disease of Bartholin gland

1.95

1.85

1.1

1.2

59.09

54.65

u/l

0.16

Postmenopausal atrophic vaginitis

177

868

1.23

1.85

1.2

61.61

59.03

u/l

0.25

127

596

Ptosis of eyelid

391

1.44

1.85

1.2

47.32

58.60

u/l

1.43

273

Schizoid personality disorder

2.23

1.85

1.2

41.14

46.68

u/l

—

Carcinoma in situ of skin of upper limb, including shoulder

2.23

1.85

1.4

1.2

87.37

52.00

u/l

—

Flat foot [pes planus] (acquired)

342

1.47

1.84

1.1

59.79

61.78

u/l

0.07

216

Haemangioma, any site

229

1.58

1.84

1.2

1.1

53.89

56.94

u/l

0.20

157

Trigeminal neuralgia

190

1.64

1.84

1.2

57.56

54.84

u/l

0.20

139

Benign neoplasm: Endocrine pancreas

4.24

1.83

1.0

1.4

49.20

48.00

u/l

—

Other hereditary haemolytic anaemias

4.24

1.83

1.0

1.2

34.80

68.33

u/l

—

Migraine without aura

716

1.32

1.83

1.1

1.2

65.75

63.24

u/l

0.12

490

Acute myringitis

4.23

1.83

1.4

1.2

214.00

79.17

u/l

—

Vasomotor rhinitis (mode)

246

1.55

1.81

1.1

1.2

55.79

63.65

u/l

0.41

171

Benign neoplasm: Skin, unspecified

1.93

1.80

1.4

1.2

60.82

58.24

u/l

0.05

Oral leukoplakia and related diseases, including avohilmo

303

1.49

1.80

1.3

1.2

51.83

55.63

u/l

0.25

207

Other obstetric conditions, not elsewhere classified

121

616

1.28

1.80

1.2

66.59

59.35

u/l

0.25

418

Olecranon bursitis

176

1.66

1.79

1.2

75.05

64.15

u/l

0.29

117

Contusion of ankle

109

1.85

1.77

1.1

63.43

66.00

u/l

0.07

Other abnormal uterine and vaginal bleeding

143

819

1.25

1.77

1.2

56.88

59.14

u/l

0.18

559

Other and unspecified nonorganic psychotic disorders

625

1.33

1.76

1.1

1.2

66.61

60.83

u/l

0.25

437

Family history of certain disabilities and chronic diseases leading to disablement

102

1.87

1.76

1.2

1.1

96.29

66.16

u/l

—

Other and unspecified erythematous conditions

1.91

1.76

1.0

1.1

47.31

53.94

u/l

0.52

Hyperplasia of prostate

167

776

1.23

1.75

1.2

64.79

66.90

u/l

0.08

524

Disturbance of activity and attention

198

1.60

1.74

1.3

1.2

99.42

76.06

u/l

0.39

135

Cleft lip, lip and palate or palate

2.52

1.74

1.2

56.00

74.85

u/l

—

Vasomotor and allergic rhinitis

189

1549

1.20

1.74

1.2

63.71

68.44

u/l

0.22

130

1060

Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium

116

590

1.28

1.74

1.2

67.20

59.76

u/l

0.25

397

Idiopathic pulmonary fibrosis

217

1.57

1.73

1.2

59.44

63.46

u/l

0.14

148

Meningitis

155

1.69

1.72

1.2

60.35

55.04

u/l

0.22

111

Complications of genitourinary prosthetic devices, implants and grafts

2.15

1.72

1.3

1.1

83.43

50.71

u/l

—

Other congenital malformations of circulatory system

1.97

1.70

1.3

1.2

52.67

53.67

u/l

—

Pathological resorption of teeth

1.96

1.70

1.3

1.2

59.40

60.75

u/l

—

Other/unspecified enthesopathies, not elsewhere classified

291

1.48

1.69

1.3

1.2

58.32

56.61

u/l

0.08

197

Bacterial meningitis

111

1.81

1.69

1.3

1.2

51.50

52.24

u/l

0.02

Dermatitis due to ingested food

2.13

1.69

1.2

1.1

127.43

210.71

u/l

—

Lesion of radial nerve

111

1.81

1.69

1.0

1.2

53.23

53.61

u/l

0.01

Diseases of male genital organs

237

1012

1.19

1.69

1.2

66.25

76.58

u/l

0.62

155

705

Other hearing loss

140

1115

1.24

1.68

1.2

54.83

62.19

u/l

1.06

751

Other and unspecified tonsillitis

128

869

1.25

1.68

1.2

58.24

75.15

u/l

1.33

604

Other disorders of ear

533

3185

1.12

1.68

1.2

58.10

64.48

u/l

1.13

341

2167

Colorectal cancer

114

903

1.27

1.68

1.1

1.2

92.64

62.11

u/l

0.86

589

Other erythematous conditions

104

1.84

1.67

1.1

47.31

54.37

u/l

0.59

Viral pneumonia (known virus, not influenza)

2.11

1.66

1.3

1.2

45.71

129.84

u/l

—

LSIL lesion of the vulva

1.90

1.65

1.2

57.00

55.25

u/l

0.07

Postpartum haemorrhage

833

0.75

1.65

1.2

60.38

60.45

u/l

0.00

573

Other neurotic disorders

150

1.68

1.63

1.5

1.2

51.50

54.34

u/l

0.15

104

conjunctival haemorrhage

245

1.52

1.62

1.3

1.2

50.28

58.11

u/l

0.95

169

Benign neoplasm: Endocrine pancreas

3.63

1.62

1.0

1.1

49.20

48.56

u/l

—

Cluster headache, wide,, including avohilmo

158

1.65

1.62

1.3

1.2

50.61

56.14

u/l

0.58

109

Sequelae of injuries of head

158

1.65

1.62

1.2

68.73

57.20

u/l

0.27

111

Pre-eclampsia or eclampsia

120

961

1.25

1.62

1.2

56.66

57.16

u/l

0.04

650

Glaucoma secondary to eye inflammation

3.61

1.62

1.2

1.0

43.60

44.13

u/l

—

Malignant neoplasm of tongue, excluding all cancers (controls excluding all cancers)

2.16

1.61

1.4

1.2

41.14

53.00

u/l

—

Other aneurysm

151

1.66

1.60

1.4

1.1

79.71

58.52

u/l

0.45

102

Hyperprolactinaemia

1.92

1.60

1.2

56.30

54.83

u/l

—

Artificial joint operation, meniscal resection

527

3154

1.11

1.59

1.2

58.21

62.98

u/l

0.86

338

2147

Antenatal screening

558

0.76

1.58

1.2

71.72

56.82

u/l

0.38

384

Alcohol abuse, main dg

498

1.35

1.58

1.1

1.2

58.17

62.96

u/l

0.32

333

Disorders of puberty

2.71

1.58

1.0

206.57

118.29

u/l

—

Irregular menses

257

1795

1.16

1.58

1.2

59.14

59.53

u/l

0.04

172

1227

Congenital malformations of heart and great arteries

375

1.40

1.58

1.3

1.2

187.68

85.27

u/l

0.52

266

Mental and behavioural disorders due to multiple drug use and use of multiple drugs and use of other psychoactive substances

183

1.59

1.57

1.1

1.2

64.76

57.67

u/l

0.24

129

Pre-existing hypertension complicating pregnancy, childbirth and the puerperium

239

1.51

1.57

1.1

1.2

66.77

62.07

u/l

0.11

167

Extrapyramidal and movement disorders

188

1582

1.19

1.57

1.2

61.64

61.95

u/l

0.02

114

1054

Adverse effects, not elsewhere classified

717

1.29

1.56

1.2

55.22

67.41

u/l

0.99

496

Maternal care related to the fetus and amniotic cavity and possible delivery problems

190

1329

0.84

1.56

1.2

66.79

58.09

u/l

0.53

133

918

Orthopaedic devices associated with adverse incidents

2.13

1.56

1.4

1.2

—

52.02

—

Carcinoma in situ of other and unspecified genital organs

2.13

1.56

1.1

1.2

58.57

55.73

u/l

—

Colorectal adenocarcinoma

709

1.29

1.55

1.1

1.2

96.19

63.95

u/l

0.70

456

Other demyelinating diseases of the central nervous system

107

1.79

1.55

1.1

1.2

39.70

54.97

u/l

—

Other mental disorders due to brain damage and dysfunction and to physical disease

364

1.41

1.55

1.3

1.2

60.33

58.47

u/l

0.07

238

Injury of muscle and tendon at hip and thigh level

289

1.46

1.54

1.1

1.2

52.62

57.16

u/l

0.32

200

Benign neoplasm: Skin of scalp and neck

1.99

1.54

1.1

1.2

58.43

52.27

u/l

—

Other benign neoplasms of connective and other soft tissue

281

1.46

1.54

1.3

1.1

60.46

62.68

u/l

0.07

193

Rosacea

407

1.38

1.53

1.2

56.95

53.91

u/l

0.16

280

Dementia in other diseases classified elsewhere

130

1.70

1.53

1.4

1.1

62.36

52.21

u/l

0.34

Adenocarcinoma, papilloma adenocarcinoma and mucinous carcinomas of rectum, excluding all cancers (controls excluding all cancers)

265

1.48

1.53

1.1

1.2

100.42

58.15

u/l

0.41

167

Other shoulder lesions

290

1.45

1.52

1.1

1.2

66.43

59.34

u/l

0.23

192

Coxarthrosis, primary, with hip surgery

255

2090

1.16

1.52

1.2

57.23

59.72

u/l

0.25

168

1386

Pre-eclampsia

108

862

1.26

1.52

1.2

55.42

57.21

u/l

0.14

578

Adenocarcinoma and papilloma adenocarcinoma of rectum, excluding all cancers (controls excluding all cancers)

249

1.49

1.52

1.1

1.2

103.08

56.39

u/l

0.44

157

Other and/or unspecified nontoxic goitre

332

1.42

1.52

1.1

1.2

48.56

55.36

u/l

0.85

228

Kela-code for severe mental illness

182

1533

1.19

1.51

1.1

1.2

58.05

62.56

u/l

0.43

126

1037

Benign neoplasm: Parotid gland

209

1.54

1.51

1.3

1.1

72.59

56.01

u/l

0.70

143

Visual field defects

266

1.47

1.51

1.1

53.52

59.93

u/l

0.40

180

Glaucoma

309

2378

1.14

1.51

1.2

57.33

61.11

u/l

0.58

215

1569

Nonsuppurative otitis media

584

1.29

1.50

1.2

128.53

76.96

u/l

0.43

406

Gonococcal infection

101

1.79

1.49

1.1

56.58

55.10

u/l

0.04

Tongue abnormality

202

1.54

1.48

1.3

1.2

63.10

53.13

u/l

0.43

147

Malignant neoplasm of respiratory system and intrathoracic organs

697

1.27

1.48

1.1

1.2

65.30

64.15

u/l

0.04

459

COPD, hospital admissions 1, only main diagnosis

169

1205

1.20

1.48

1.1

1.2

57.68

62.49

u/l

0.40

109

783

Other disorders of Eustachian tube

1.82

1.48

1.1

60.30

52.00

u/l

—

Medial epicondylitis

124

1.70

1.47

1.2

48.17

54.82

u/l

0.41

Effects of foreign body entering through natural orifice

105

839

1.25

1.47

1.2

53.20

70.33

u/l

2.20

567

Haemorrhage in early pregnancy

1210

0.80

1.47

1.2

58.10

57.04

u/l

0.08

804

Pregnancy hypertension

220

1700

1.17

1.47

1.2

59.76

58.03

u/l

0.18

157

1153

Haemorrhagic disorder due to circulating anticoagulants

2.53

1.46

1.4

1.1

51.00

40.72

u/l

—

Emphysema

195

1.54

1.45

1.2

1.1

56.86

61.71

u/l

0.13

133

Leiomyosarcoma

3.17

1.44

1.4

1.2

65.00

48.75

u/l

—

Other contact dermatitis

244

1.48

1.44

1.3

1.1

57.17

58.73

u/l

0.07

164

Other specified/unspecified spondylopathies

1.93

1.44

1.1

1.2

41.00

46.73

u/l

—

Other benign neoplasm of uterus: Other parts/unspecified

125

1.69

1.44

1.2

41.50

67.72

u/l

3.40

Atrial septal defect

109

1.74

1.44

1.5

1.2

357.91

116.35

u/l

0.36

Exclusion endpoint for supernumerary teeth

2.75

1.44

1.2

1.1

65.33

155.69

u/l

—

Benign neoplasm: Larynx

1.98

1.43

1.1

1.2

51.38

52.51

u/l

—

Hyperkinetic disorders

217

1.50

1.43

1.3

1.2

105.44

85.33

u/l

0.32

150

Benign neoplasm of brain and other parts of central nervous system

164

1.59

1.43

1.2

97.07

57.52

u/l

0.61

113

Pneumothorax

196

1.54

1.43

1.2

77.45

54.46

u/l

0.67

133

Other and unspecified injuries of wrist and hand

103

1.76

1.41

1.3

1.2

58.46

58.62

u/l

0.00

Benign neoplasm of major salivary glands

287

1.43

1.40

1.3

1.1

66.28

55.74

u/l

0.50

190

Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis

1.86

1.40

1.3

1.2

59.60

49.29

u/l

—

Sequelae of other and unspecified infectious and parasitic diseases

165

1.58

1.40

1.4

1.2

68.61

55.05

u/l

0.42

117

LSIL lesion of the cervix uteri

346

1.39

1.40

1.1

1.2

61.47

58.61

u/l

0.13

230

Perineal laceration during delivery

409

0.67

1.39

1.3

1.2

57.65

63.11

u/l

0.29

283

Atrophic disorders of skin

571

1.30

1.39

1.1

1.2

56.61

62.45

u/l

0.53

388

Essential (haemorrhagic) thrombocythaemia

1.78

1.39

1.5

1.2

41.64

52.97

u/l

0.70

Malignant neoplasm, without specification of site, excluding all cancers (controls excluding all cancers)

1.78

1.38

1.1

1.2

77.73

52.53

u/l

0.49

Pain and other conditions associated with female genital organs and menstrual cycle

734

1.26

1.38

1.1

1.2

51.81

59.80

u/l

1.08

496

Other specified/unspecified soft tissue disorders

142

1.63

1.38

1.3

1.2

52.67

62.02

u/l

0.53

102

Correction of physiology of bite - demanding therapy visit

214

1.50

1.38

1.2

67.96

56.36

u/l

0.40

142

Other specified and unspecified disorders of eye and adnexa

119

1.69

1.38

1.5

1.2

59.21

53.31

u/l

0.27

Septal defects

170

1.56

1.37

1.5

1.2

271.59

113.80

u/l

0.37

121

Maternal care for cervical incompetence

127

1.66

1.37

1.4

1.2

59.25

55.54

u/l

0.17

Other symptoms and signs involving the urinary system

314

1.41

1.36

1.3

1.2

58.37

60.77

u/l

0.16

215

Bitten or struck by other mammals

331

1.39

1.36

1.1

1.2

53.80

75.88

u/l

1.06

234

Contact with and exposure to communicable diseases

127

1043

1.21

1.35

1.2

88.11

65.81

u/l

0.43

716

Melanocytic naevi of upper limb, including shoulder

1.88

1.35

1.2

1.1

55.00

61.76

u/l

—

Lichen planus

504

1.31

1.35

1.2

60.15

58.84

u/l

0.06

340

Benign neoplasm: Long bones of lower limb

105

1.72

1.33

1.1

1.2

57.38

52.44

u/l

—

Alzheimer’s disease (Late onset), excluding more controls

359

0.70

1.33

1.1

1.2

53.96

68.24

u/l

0.79

239

Fracture of neck

168

1.55

1.31

1.3

1.2

55.11

56.67

u/l

0.05

116

Malignant neoplasm of oral cavity

1.75

1.31

1.3

1.2

47.18

52.48

u/l

0.25

Focal epilepsy

755

1.25

1.29

1.1

1.2

67.38

71.95

u/l

0.16

507

Malignant neoplasm of ureter, excluding all cancers (controls excluding all cancers)

2.81

1.29

1.2

110.40

53.00

u/l

—

Inflammatory disorders of breast

185

1.52

1.29

1.1

1.2

61.32

64.48

u/l

0.13

128

Malignant neoplasm of bronchus and lung

598

1.27

1.29

1.1

1.2

66.41

61.36

u/l

0.20

402

Acne vulgaris

177

1.53

1.28

1.4

1.2

74.64

67.59

u/l

0.20

122

Other spirochaetal diseases

133

1110

1.20

1.27

1.1

1.2

51.63

63.48

u/l

2.41

750

Medical abortion

374

1820

1.12

1.27

1.2

56.91

59.58

u/l

0.44

248

1237

Schizophrenia or delusion, excluding more controls

135

1120

1.20

1.26

1.1

1.2

67.69

60.31

u/l

0.52

765

Pre-eclampsia or poor fetal growth

148

1245

1.19

1.26

1.3

1.2

54.54

57.86

u/l

0.37

851

Disorders of orbit

138

1.60

1.26

1.1

1.2

58.18

54.37

u/l

0.19

Alopecia areata

1.83

1.25

1.0

1.1

44.00

96.87

u/l

—

Childhood allergy (age < 16)

248

1.40

1.25

1.2

104.73

125.33

u/l

0.30

187

Neuroendocrine tumor and carcinoma of small intestine, excluding all cancers (controls excluding all cancers)

2.42

1.24

1.3

1.2

52.33

46.86

u/l

—

Prolonged pregnancy

440

0.70

1.24

1.1

1.2

56.27

58.59

u/l

0.13

307

malignant neoplasm of female genital organs

688

0.75

1.24

1.2

53.18

58.13

u/l

0.54

449

Mouth breathing

201

1740

1.16

1.24

1.2

57.84

67.15

u/l

1.63

154

1162

Benign neoplasm of thyroid gland

1.77

1.23

1.1

56.14

53.87

u/l

—

Combinations of oral blood glucose lowering drugs

136

1142

1.19

1.23

1.2

55.27

64.48

u/l

1.32

103

753

≡ Risteys

FG R12 + FR

FinnGen R11 + FinRegistry

FinnGen R10 + FinRegistry

FinnGen R10

FinnGen R9

FinnGen R8

FinnGen R7

FinnGen R6

FinnGen R5

FinnGen R4

FinnGen R3

Alkaline phosphatase.bone [Enzymatic activity/volume] in Serum or Plasma

Coding

Definition

OMOP mapping QC

Cohort

Year of birth distribution

Age at first measurement

Age at last measurement

Age at start of registry

Duration from first to last measurement

Statistics

Number of measurements over the years

Number of measurements per person

Distribution of lab values

Value range per person

LabWAS