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Dementia in Alzheimer disease

DOID EFO Endpoint Browser PheWeb

F5_ALZHDEMENT

Alzheimer's disease: A progressive, neurodegenerative disease characterized by loss of function and death of nerve cells in several areas of the brain leading to loss of cognitive function such as memory and language.

Suggest a new description

Endpoint definition

↥

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — F00*
  • Hospital discharge: ICD-8 — 29010
  • Cause of death: ICD-10 — F00*
  • Cause of death: ICD-8 — 29010

2 out of 7 registries used, show all original rules.

8188

4. Check minimum number of events

None

8188

5. Include endpoints

None

8188

6. Filter based on genotype QC (FinnGen only)

8188

Control definitions (FinnGen only)

Control exclude
F5_ORGANIC

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF3

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 128670 81960 45831
Only index persons 110175 71387 38788
Unadjusted period prevalence (%)
Whole population 1.96 2.35 1.28
Only index persons 2.22 2.62 1.48
Median age at first event (years)
Whole population 82.30 83.00 81.09
Only index persons 82.63 83.30 81.39

-FinnGen-

Key figures

All Female Male
Number of individuals 8188 3846 4342
Unadjusted period prevalence (%) 1.63 1.31 1.91
Median age at first event (years) 80.58 80.52 80.62

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
5794
Matched controls
53800
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
F00.20*G30.8
ICD-10 Finland
Dementia in Alzheimer's disease, atypical or mixed type without additional symptoms
196.0
323.0
1360
84
F00.10
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, senile onset without additional symptoms
1041.6
323.0
1095
12
G30.0
ICD-10 Finland
Alzheimer disease with early onset
263.2
323.0
445
17
G30.8
ICD-10 Finland
Other Alzheimer disease
105.5
323.0
1014
108
N05AH04
ATC
quetiapine; oral
8.0
323.0
1423
2114
N06DX01
ATC
memantine; oral
546.7
323.0
3495
147
F06.7
ICD-10 Finland
Mild cognitive disorder
19.7
323.0
522
269
F009, G309
ICD-10 Finland
NA
+∞
323.0
353
*
N06DA02
ATC
donepezil; oral
317.7
323.0
2647
142
F00.10*G30.1
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, senile onset without additional symptoms
533.2
323.0
2511
77
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
7.2
323.0
1350
2171
N06DA04
ATC
galantamine; oral
236.3
323.0
811
37
F0019, G301
ICD-10 Finland
NA
+∞
323.0
524
*
N06DA03
ATC
rivastigmine; oral, transdermal
385.4
323.0
1703
58
G30.1
ICD-10 Finland
Alzheimer disease with late onset
117.4
323.0
2700
397
P70
ICPC
Dementia
49.1
323.0
789
172
P20
ICPC
Memory disturbance
9.3
323.0
2610
4362
SPAT1053
SPAT
Memory test
5.2
323.0
2460
6699
G30
ICD-10 Finland
Alzheimer disease
174.9
323.0
468
27
307
Kela drug reimbursment
Tacrine, donepezil, rivastigmine, galantamine and other major and expensive drugs used to treat Alzheimer's disease
+∞
323.0
2794
*
F00.9
ICD-10 Finland
Dementia in Alzheimer disease, unspecified
464.4
323.0
420
9
F00.20
ICD-10 Finland
Dementia in Alzheimer's disease, atypical or mixed type without additional symptoms
820.2
323.0
701
9
F00.00*G30.0
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, presenile onset without additional symptoms
+∞
323.0
503
*
F03
ICD-10 Finland
Unspecified dementia
51.2
323.0
1301
302
N05AX08
ATC
risperidone; systemic
22.8
323.0
1822
1062
G30.9
ICD-10 Finland
Alzheimer disease, unspecified
135.5
323.0
1606
152
SPAT1245
SPAT
Provision of support and information to patient’s family members
6.4
292.8
846
1392
SPAT1234
SPAT
Support of social functional capacity
6.0
280.9
864
1537
SPAT1216
SPAT
Assessment of functional ability
3.1
248.3
1687
6216
SPAT1137
SPAT
Taking care of patient’s/customer’s hygiene
4.4
239.6
996
2441
N05BA04
ATC
oxazepam; oral
2.9
232.3
1846
7496
SPAT1222
SPAT
Counselling/guidance promoting independent living
3.0
227.6
1615
6069
F05.1
ICD-10 Finland
Delirium superimposed on dementia
1000.0
207.7
208
*
SPAT1254
SPAT
Administration of medicine
3.0
204.0
1443
5352
R53
ICD-10 Finland
Malaise and fatigue
2.7
199.9
1706
7115
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
2.4
193.3
2340
11797
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
3.4
191.6
1073
3347
F05.9
ICD-10 Finland
Delirium, unspecified
63.1
191.3
229
35
F00.00
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, presenile onset without additional symptoms
606.1
187.6
190
*
F0009, G300
ICD-10 Finland
NA
+∞
176.1
173
*
N06AX11
ATC
mirtazapine; oral
2.4
166.6
1857
8810
A28
ICPC
Limited function/disability NOS
2.5
162.9
1654
7452
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.4
158.2
1649
7513
R41.0
ICD-10 Finland
Disorientation, unspecified
5.9
150.4
456
772
AA1AD
NOMESCO Finland
CT of head and brain
2.3
147.5
1876
9374
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.1
144.7
2352
13097
N02BE01
ATC
paracetamol; systemic, rectal
2.3
144.5
4680
34785
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
2.8
140.1
1031
3809
F0029, G308
ICD-10 Finland
NA
+∞
139.3
137
*
N03AG01
ATC
valproic acid; systemic, rectal
5.6
130.2
406
709
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.5
128.2
1265
5501
N06AB10
ATC
escitalopram; oral
3.0
125.8
832
2850
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
3.9
120.9
542
1375
WYA20
NOMESCO Finland
Home visit
9.6
120.2
259
262
F0014, G301
ICD-10 Finland
NA
+∞
118.9
117
*
F001, G301
ICD-10 Finland
NA
552.5
115.1
117
*
N05AH03
ATC
olanzapine; systemic
6.6
113.0
311
461
F00.14
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, senile onset other additional symptoms of mixed type
+∞
112.7
111
*
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
3.8
106.7
493
1280
F01.9
ICD-10 Finland
Vascular dementia, unspecified
28.0
106.5
150
51
SPAT1360
SPAT
Extensive global examination
3.0
100.4
645
2148
F00
ICD-10 Finland
Dementia in Alzheimer disease
47.4
99.8
125
25
F00.1
ICD-10 Finland
Dementia in Alzheimer disease with late onset
+∞
98.5
97
*
SPAT1301
SPAT
No procedures
1.9
98.2
2015
11793
SPAT1101
SPAT
Orthostatic test
3.3
96.9
539
1619
G91.2
ICD-10 Finland
Normal-pressure hydrocephalus
8.0
95.2
227
272
L28
ICPC
Limited function/disability (L)
2.1
94.9
1335
6728
TAB00
NOMESCO Finland
Lumbar puncture
6.1
93.9
271
427
SPAT1229
SPAT
Assessment of need for aid
2.6
93.4
771
2992
F00.19
ICD-10 Finland
Dementia in Alzheimer's disease with late onset without information about additional symptoms
446.3
92.9
95
*
SPAT1304
SPAT
Counselling and guidance related to ageing
2.5
92.6
823
3325
N05BA06
ATC
lorazepam; systemic, sublingual
3.4
92.5
485
1391
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.1
92.5
1278
6385
SPAT1172
SPAT
Guidance concerning hydration
4.3
86.6
345
779
U04
ICPC
Incontinence urine
3.3
86.3
471
1391
R41.3
ICD-10 Finland
Other amnesia
4.8
84.6
302
610
Z75.5
ICD-10 Finland
Holiday relief care
7.8
84.4
205
253
A06AD11
ATC
lactulose; oral
2.0
83.0
1385
7415
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.1
82.7
1066
5135
N06AB04
ATC
citalopram; systemic
2.1
82.1
1153
5758
A04
ICPC
Weakness/tiredness general
2.2
82.1
948
4348
SPAT1292
SPAT
Other function in accordance with SHToL (Finnish classification of nursing interventions)
2.5
78.4
702
2831
SPAT1263
SPAT
Sampling
1.7
77.8
2262
14534
N05AD01
ATC
haloperidol; systemic
3.9
76.4
340
849
F00, F03
ICD-10 Finland
NA
+∞
75.1
74
*
S72.0
ICD-10 Finland
Fracture of neck of femur
2.8
73.2
506
1751
SPAT1305
SPAT
Counselling and guidance related to physical exercise
2.4
71.7
678
2806
SPAT1252
SPAT
Overall medication plan or its review
2.5
70.8
598
2327
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
3.1
65.4
395
1248
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.7
65.1
1801
11238
130
Kela drug reimbursment
Malignant tumour
0.3
64.7
111
3755
N06AX26
ATC
vortioxetine; oral
4.9
64.2
222
433
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
2.0
62.9
989
5108
N02AA05
ATC
oxycodone; systemic
1.9
62.0
1143
6249
AAF05
NOMESCO Finland
Ventriculoperitoneal shunt
7.1
61.3
157
210
NFB20
NOMESCO Finland
Primary partial prosthetic replacement of hip joint using cement, other or unspecified
3.3
60.9
333
980
SPAT1167
SPAT
Insertion of urinary catheter
2.9
56.8
372
1240
F0011, G301
ICD-10 Finland
NA
+∞
56.8
56
*
I95.1
ICD-10 Finland
Orthostatic hypotension
2.8
56.6
390
1341
SPAT1251
SPAT
Organisation of medication
3.0
56.4
359
1173
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.9
55.5
969
5172
SAD01
NOMESCO Finland
Assessment of need for oral health care, standard
2.6
55.5
453
1721
S01.0
ICD-10 Finland
Open wound of scalp
2.4
55.1
519
2130
S06.0
ICD-10 Finland
Concussion
2.3
54.9
576
2491
SPAT1246
SPAT
Screening of depression or other psychiatric problem
5.0
54.3
183
347
E86
ICD-10 Finland
Volume depletion
3.6
54.2
264
710
F05.8
ICD-10 Finland
Other delirium
80.4
52.2
60
7
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.6
51.7
1686
10858
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
2.9
51.0
335
1118
F009, F03
ICD-10 Finland
NA
+∞
49.7
49
*
SPAT1249
SPAT
Treatment-related counselling outside office
1.6
48.9
1898
12733
R55
ICD-10 Finland
Syncope and collapse
1.9
48.4
828
4369
F00.11
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, senile onset other additional symptoms, mainly paranoidism
456.8
48.0
49
*
Z02.4
ICD-10 Finland
Examination for driving licence
0.6
47.5
703
10583
SPAT1262
SPAT
Handing over of treatment supplies
1.7
47.2
1067
6166
S70.0
ICD-10 Finland
Contusion of hip
2.9
47.0
314
1057
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
2.4
46.8
442
1813
F00.24
ICD-10 Finland
Dementia in Alzheimer's disease, atypical or mixed type other additional symptoms of mixed type
229.3
46.6
49
*
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.5
46.5
385
1472
W19
ICD-10 Finland
Unspecified fall
2.1
46.0
571
2656
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.6
45.5
1518
9767
SAB01
NOMESCO Finland
Restricted oral and dental health check by dental hygienist or dental assistant
2.7
44.4
328
1176
F0024, G308
ICD-10 Finland
NA
+∞
43.6
43
*
N07AA05
ATC
NA
+∞
42.6
42
*
J01DB01
ATC
cefalexin; oral
1.5
41.4
3754
29870
SPAT1231
SPAT
Assessment of adjustments needed in living environment
3.2
40.7
227
677
F01.20
ICD-10 Finland
Subcortical vascular dementia without additional symptoms
14.6
40.6
70
45
SPAT1226
SPAT
Implementation of occupational therapy rehabilitation plan
3.2
40.6
229
687
F00.09
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, presenile onset information on additional symptoms is lacking
+∞
40.5
40
*
G40.9
ICD-10 Finland
Epilepsy, unspecified
3.2
40.4
222
655
C10AA01
ATC
simvastatin; oral
1.4
38.1
3006
23066
N30.0
ICD-10 Finland
Acute cystitis
1.8
37.7
767
4264
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
2.1
37.3
434
1958
R42
ICD-10 Finland
Dizziness and giddiness
1.6
37.0
1350
8799
H02AB02
ATC
dexamethasone; systemic
0.3
36.9
114
2934
B01AC30
ATC
platelet aggregation inhibitors excl. heparin - combinations
1.9
36.7
604
3122
R4110
NOMESCO Finland
Physiotherapy
0.6
36.6
593
8799
F002, G308
ICD-10 Finland
NA
+∞
36.5
36
*
G31.8
ICD-10 Finland
Other specified degenerative diseases of nervous system
15.0
36.0
61
38
F05.0
ICD-10 Finland
Delirium not superimposed on dementia, so described
343.3
36.0
37
*
F01.29
ICD-10 Finland
Subcortical vascular dementia without information on additional symptoms
57.4
35.9
43
7
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
2.5
35.7
304
1179
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.2
35.7
397
1755
SPAT1139
SPAT
Nutrition survey
2.9
35.1
224
733
N05AD03
ATC
melperone; systemic
4.2
35.0
139
314
F02.39*G20
ICD-10 Finland
Dementia in Parkinson's disease without information on additional symptoms
333.9
35.0
36
*
F00.12
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, senile onset, other additional symptoms, mainly hallucinations
172.8
34.7
37
*
A49.9
ICD-10 Finland
Bacterial infection, unspecified
1.7
34.3
760
4326
N06AB06
ATC
sertraline; oral
2.3
34.3
333
1382
Z02.7
ICD-10 Finland
Issue of medical certificate
2.3
34.2
346
1463
SPAT1276
SPAT
Outlining of treatment with patient or their family members
3.1
34.2
194
586
R1250
NOMESCO Finland
Evaluation of functional capability
4.5
33.5
124
262
F00.2
ICD-10 Finland
Dementia in Alzheimer disease, atypical or mixed type
+∞
33.4
33
*
G04CA02
ATC
tamsulosin; oral
1.4
33.4
1913
13684
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
4.4
33.4
125
267
J01CA08
ATC
pivmecillinam; oral
1.5
33.1
1620
11222
SPAT1260
SPAT
Consultation of another employee
1.6
32.9
904
5466
AXX01
SPAT
NA
4.2
32.9
131
297
F01.19
ICD-10 Finland
Multi-infarct dementia without information on additional symptoms
163.4
32.7
35
*
B03BA03
ATC
hydroxocobalamin; parenteral
1.9
32.5
485
2418
F00.13
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, senile onset other additional symptoms, mainly depression
+∞
32.4
32
*
F22.0
ICD-10 Finland
Delusional disorder
5.5
32.2
98
167
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.4
31.2
1868
13427
R56.8
ICD-10 Finland
Other and unspecified convulsions
2.6
30.9
244
907
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.7
30.8
771
4535
WX402
NOMESCO Finland
General anaesthesia
0.4
30.7
140
3079
R99
ICD-10 Finland
Other ill-defined and unspecified causes of mortality
3.0
30.3
187
600
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
1.7
30.2
654
3689
F0012, G301
ICD-10 Finland
NA
+∞
29.4
29
*
SPAT1279
SPAT
Preparation of immediate hospitalisation
3.9
29.0
125
305
SPAT1307
SPAT
Psychosocial counselling and guidance
3.5
28.5
137
367
F00.01
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, presenile onset other additional symptoms, mainly paranoidism
+∞
28.4
28
*
Z29
ICPC
Social problem NOS
3.9
28.3
119
284
S72.1
ICD-10 Finland
Pertrochanteric fracture
2.5
28.3
232
882
F00.21
ICD-10 Finland
Dementia in Alzheimer's disease, atypical or mixed type of other additional symptoms, mainly paranoidism
272.2
27.9
29
*
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.6
27.8
886
5543
F29
ICD-10 Finland
Unspecified nonorganic psychosis
5.1
27.7
90
166
A03FA01
ATC
metoclopramide; systemic, rectal
0.6
27.4
496
7221
R41
ICD-10 Finland
Other symptoms and signs involving cognitive functions and awareness
6.0
27.1
77
121
SPAT1125
SPAT
Stoma care and guidance
3.0
27.0
158
490
J69.0
ICD-10 Finland
Pneumonitis due to food and vomit
2.7
26.2
184
640
XA800
NOMESCO Finland
Neuropsychological investigation
3.6
25.7
121
319
S06.5
ICD-10 Finland
Traumatic subdural haemorrhage
2.2
25.5
283
1249
N06AX16
ATC
venlafaxine; oral
2.0
25.1
335
1595
LAITO
NOMESCO Finland
NA
30.8
24.6
33
10
E0000UV
ATC
NA
1.4
24.5
1690
12338
F21
ICPC
NA
4.4
24.4
90
191
G04CB01
ATC
finasteride; oral (testosterone-5-alpha reductase inhibitors)
1.5
23.8
1038
6948
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.3
23.3
1995
15061
F0021, G308
ICD-10 Finland
NA
+∞
23.3
23
*
F00.22
ICD-10 Finland
Dementia in Alzheimer's disease, atypical or mixed type other additional symptoms, mainly hallucinations
+∞
23.3
23
*
A29
ICPC
General symptom/complaint other
1.6
22.9
587
3463
A10AE04
ATC
insulin glargine; parenteral
1.7
22.8
487
2727
NF1AA
NOMESCO Finland
Hip X-ray examination
1.7
22.8
550
3187
TPH04
NOMESCO Finland
Cathetrisation of vein
0.6
22.8
545
7494
Z51.88
ICD-10 Finland
Other specified medical care
3.0
22.6
137
436
NFJ54
NOMESCO Finland
Internal fixation of fracture of upper femur with intramedullary nail
2.7
22.6
159
556
R33
ICD-10 Finland
Retention of urine
1.6
22.3
667
4093
SPAT1104
SPAT
Monitoring of emergency patient
1.8
22.3
381
1988
F01.2
ICD-10 Finland
Subcortical vascular dementia
13.5
22.3
39
27
F0013, G301
ICD-10 Finland
NA
+∞
22.3
22
*
F0022, G308
ICD-10 Finland
NA
+∞
22.3
22
*
N02AJ06
ATC
codeine and paracetamol; systemic
0.7
22.2
763
9789
N40
ICD-10 Finland
Hyperplasia of prostate
1.4
22.1
1699
12579
SPAT1157
SPAT
Guidance concerning treatment of mouth and mucous membranes
3.8
22.1
95
233
4912B
ICD-9 Finland
Chronic bronchitis, Obstructive chronic bronchitis[BRONCHITIS OBSTRUCTIVA CUM EMPHYSEMATE]
0.1
22.0
11
797
F00.23
ICD-10 Finland
Dementia in Alzheimer's disease, atypical or mixed type of other additional symptoms, mainly depression
214.3
22.0
23
*
SPAT1281
SPAT
Other administrative function
1.8
21.9
374
1949
Z51.5
ICD-10 Finland
Palliative care
1.8
21.8
428
2336
SPAT1284
SPAT
Extensive health certificate
2.9
21.8
136
441
SPAT1215
SPAT
Assessment of need for medical rehabilitation
2.2
21.7
219
926
G31.0
ICD-10 Finland
Circumscribed brain atrophy
9.3
21.5
45
45
SPAT1310
SPAT
Counselling related to known health issue
1.4
21.5
1410
10159
I25.9
ICD-10 Finland
Chronic ischaemic heart disease, unspecified
1.4
21.3
999
6766
F0004, G300
ICD-10 Finland
NA
+∞
21.3
21
*
F0023, G308
ICD-10 Finland
NA
+∞
21.3
21
*
SAD02
NOMESCO Finland
Assessment of need for oral health care, extensive
3.3
21.3
109
309
AAA20
NOMESCO Finland
Insertion of intraventricular pressure monitoring device
11.3
21.2
40
33
C34.1
ICD-10 Finland
Malignant neoplasm: Upper lobe, bronchus or lung
0.2
21.1
25
1042
E000001
ATC
NA
1.5
20.9
881
5837
N04BA02
ATC
levodopa and decarboxylase inhibitor; oral
2.1
20.9
247
1119
-2
ICPC
NA
4.6
20.8
74
152
J01EA01
ATC
trimethoprim; systemic
1.4
20.6
1337
9603
U07.1
ICD-10 Finland
Emergency use of U07.1 | COVID-19, virus identified
2.0
20.6
288
1400
F009, G301
ICD-10 Finland
NA
+∞
20.3
20
*
2900A
ICD-9 Finland
Senile and presenile organic psychotic conditions, Senile dementia, uncomplicated
+∞
20.3
20
*
AA5DR
NOMESCO Finland
Brain metabolism PET with CT
+∞
20.3
20
*
WX002
NOMESCO Finland
Sedation and analgesia
0.6
20.3
507
6922
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
0.2
19.8
21
937
F06.9
ICD-10 Finland
Unspecified mental disorder due to brain damage and dysfunction and to physical disease
38.8
19.7
25
6
Z13.3
ICD-10 Finland
Special screening examination for mental and behavioural disorders
20.8
19.5
29
13
Z03
ICPC
Housing/neighbourhood problem
5.5
19.5
58
98
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
0.4
19.3
73
1730
F0024, G301
ICD-10 Finland
NA
+∞
19.2
19
*
A98
ICPC
Health maint/preventive medicine
1.3
19.2
3978
33670
F01.30
ICD-10 Finland
Mixed cortical and subcortical vascular dementia without additional symptoms
14.9
19.2
32
20
R44.3
ICD-10 Finland
Hallucinations, unspecified
8.2
19.2
43
49
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
3.1
19.1
109
334
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
3.4
18.9
92
251
F00.29
ICD-10 Finland
Dementia in Alzheimer's disease, atypical or mixed type without information on additional symptoms
97.8
18.9
21
*
SPAT1100
SPAT
Long-term monitoring of blood pressure
1.6
18.9
471
2755
F01.10
ICD-10 Finland
Multi-infarct dementia without additional symptoms
22.9
18.7
27
11
Z25.8
ICD-10 Finland
Need for immunization against other specified single viral diseases
0.4
18.6
101
2089
I67.3
ICD-10 Finland
Progressive vascular leukoencephalopathy
3.3
18.4
94
267
F01.0
ICD-10 Finland
Vascular dementia of acute onset
65.3
18.1
21
*
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
1.4
18.1
846
5711
N30.9
ICD-10 Finland
Cystitis, unspecified
1.9
18.1
293
1502
-
ICD-10 Finland
NA
2.6
18.0
138
509
A04AA02
ATC
granisetron; systemic, transdermal
0.3
17.5
44
1244
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
0.6
17.5
216
3470
N03AX14
ATC
levetiracetam; systemic
2.8
17.4
116
394
EBA15
NOMESCO Finland
Extraction of large number of teeth
2.2
17.3
177
755
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
0.2
17.1
22
873
ZX120
NOMESCO Finland
Intravenous
0.5
17.1
182
3043
R50.9
ICD-10 Finland
Fever, unspecified
1.5
17.1
675
4403
F06.0
ICD-10 Finland
Organic hallucinosis
88.5
17.0
19
*
F00.04
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, presenile onset other additional symptoms of mixed type
167.5
17.0
18
*
SPAT1295
SPAT
Other function in accordance with physical therapy nomenclature
1.8
16.8
282
1464
SPAT1033
SPAT
Irrigation or wax removal of outer auditory canal
1.3
16.7
1202
8737
P29
ICPC
Psychological sympt/compl other
2.9
16.5
103
338
L82
ICD-10 Finland
Seborrhoeic keratosis
0.6
16.4
339
4830
TPH07
NOMESCO Finland
Cathetrisation of artery
0.6
16.4
232
3607
G91.0
ICD-10 Finland
Communicating hydrocephalus
6.6
16.4
42
59
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
1.8
16.3
283
1484
L89
ICD-10 Finland
Decubitus ulcer and pressure area
2.4
16.3
136
525
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.2
16.2
172
748
N07AA06
ATC
NA
+∞
16.2
16
*
G91.9
ICD-10 Finland
Hydrocephalus, unspecified
6.9
16.1
40
54
F00.0
ICD-10 Finland
Dementia in Alzheimer disease with early onset
158.2
16.0
17
*
SPAT1221
SPAT
Guidance concerning rehabilitation services and livelihood
3.2
15.8
84
247
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
1.3
15.8
2211
17604
A10AE05
ATC
insulin detemir; parenteral
1.9
15.7
252
1288
SPAT1325
SPAT
Vaccination
1.3
15.6
1924
15071
R23.8
ICD-10 Finland
Other and unspecified skin changes
0.6
15.5
350
4897
A69
ICPC
General and Unspecified, Other reason for encounter NEC
2.2
15.4
158
675
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
0.7
15.4
613
7725
WX404
NOMESCO Finland
Intravenous generell anesthesy
0.6
15.4
360
5001
H02AA02
ATC
fludrocortisone; oral
3.5
15.1
72
195
8070/3-C34.9
ICD-O-3
Squamous cell carcinoma, NOS, of lung, NOS
0.2
15.0
16
707
SPAT1296
SPAT
Other function in accordance with occupational therapy nomenclature
3.0
14.8
85
263
R11
ICD-10 Finland
Nausea and vomiting
1.6
14.8
382
2252
WX408
NOMESCO Finland
General anesthesy, balanced
0.7
14.8
640
7957
G04CA01
ATC
alfuzosin; oral
1.4
14.6
729
4968
F01.3
ICD-10 Finland
Mixed cortical and subcortical vascular dementia
26.6
14.6
20
7
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
1.5
14.5
541
3481
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
1.9
14.4
200
970
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.3
14.3
2036
16180
L75
ICPC
Fracture: femur
2.5
14.3
111
413
G04BD08
ATC
solifenacin; oral
1.6
14.2
399
2401
Z60.8
ICD-10 Finland
Other problems related to social environment
6.9
14.2
35
47
F0019, G309
ICD-10 Finland
NA
+∞
14.2
14
*
F000, G300
ICD-10 Finland
NA
+∞
14.2
14
*
SCA01
NOMESCO Finland
Simple analysis and advice of nutrition with regard to dentistry
1.4
14.1
696
4729
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
0.7
14.0
482
6235
N05AB03
ATC
perphenazine; systemic, rectal
2.4
14.0
120
473
SPAT1138
SPAT
Guidance concerning bowel function
2.6
14.0
99
351
R74
ICPC
Upper respiratory infection acute
0.6
14.0
289
4120
SPAT1312
SPAT
General health counselling
1.3
13.8
1285
9664
E87.0
ICD-10 Finland
Hyperosmolality and hypernatraemia
5.1
13.7
43
79
SPAT1255
SPAT
Intravenous administration of medicine
1.7
13.7
318
1825
A04AA01
ATC
ondansetron; systemic, rectal
0.4
13.7
77
1568
Y94.0
ICD-10 Finland
Accident at home
2.5
13.7
111
425
P05
ICPC
Senility, feeling/behaving old
4.0
13.7
55
130
P04
ICPC
Feeling/behaving irritable/angry
11.6
13.7
25
20
NE1AA
NOMESCO Finland
Pelvis X-ray examination
1.6
13.6
377
2265
N29
ICPC
Neurological sympt/complt other
2.7
13.6
94
330
Z28
ICPC
Limited function/disability (Z)
4.7
13.6
46
92
K90
ICPC
Stroke/cerebrovascular accident
1.9
13.5
189
920
L08
ICPC
Shoulder symptom/complaint
0.7
13.5
400
5316
F02.09*G31.0
ICD-10 Finland
Dementia in Pick's disease without information on additional symptoms
49.6
13.3
16
*
SPAT1050
SPAT
Extensive neurological examination
2.3
13.3
118
474
N28
ICPC
Limited function/disability (N)
2.7
13.3
88
301
C04AE01
ATC
ergoloid mesylates; systemic
3.0
13.3
76
236
SPAT1309
SPAT
Guidance related to psychoactive substances / risk behaviour
3.0
13.2
75
231
3310A
ICD-9 Finland
Other cerebral degenerations, Alzheimer's disease
+∞
13.2
13
*
G72.8
ICD-10 Finland
Other specified myopathies
2.5
13.2
104
392
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
1.5
13.1
527
3442
G04CB02
ATC
dutasteride; oral
1.5
13.1
472
3014
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
0.7
12.9
345
4670
GD1AA
SPAT
NA
0.2
12.9
10
538
K08.3
ICD-10 Finland
Retained dental root
1.7
12.8
289
1644
XF402
NOMESCO Finland
ECG with work load test
0.6
12.8
278
3918
S01
ICD-10 Finland
Open wound of head
3.0
12.7
71
218
F22.9
ICD-10 Finland
Persistent delusional disorder, unspecified
6.3
12.6
33
49
W06
ICD-10 Finland
Fall involving bed
3.2
12.5
66
195
WF049
NOMESCO Finland
Radiotherapy of metastasis
0.3
12.5
32
896
XF400
NOMESCO Finland
ECG with 12 standard connections
0.7
12.5
624
7607
WX302
NOMESCO Finland
Thoracal epidural anesthesy
0.4
12.4
58
1262
N05CD07
ATC
temazepam; oral
1.3
12.3
873
6302
AA1AA
NOMESCO Finland
Head X-ray examination
3.5
12.3
56
148
R32
ICD-10 Finland
Unspecified urinary incontinence
2.0
12.2
152
711
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
0.8
12.2
834
9741
F0009, G309
ICD-10 Finland
NA
+∞
12.1
12
*
F009, G308
ICD-10 Finland
NA
+∞
12.1
12
*
F0001, G300
ICD-10 Finland
NA
+∞
12.1
12
*
8140/3-C34.9
ICD-O-3
Adenocarcinoma, NOS, of lung, NOS
0.1
12.1
5
410
J96.1
ICD-10 Finland
Chronic respiratory failure
0.4
12.0
48
1110
C03CA01
ATC
furosemide; systemic
1.2
11.9
2479
20418
K59.0
ICD-10 Finland
Constipation
1.6
11.9
334
2011
AA7AA
NOMESCO Finland
Liquor cerebri shunt X-ray examinatin without contrast
6.9
11.9
29
39
213
Kela drug reimbursment
Fat metabolism disorder associated with chronic coronary artery disease
1.4
11.9
688
4805
G20
ICD-10 Finland
Parkinson disease
1.9
11.8
181
915
S01.1
ICD-10 Finland
Open wound of eyelid and periocular area
2.2
11.8
116
492
K80
ICPC
Cardiac arrhythmia NOS
0.6
11.7
130
2148
J22
ICD-10 Finland
Unspecified acute lower respiratory infection
1.8
11.7
206
1089
XFP96
NOMESCO Finland
Other intraoperative electrophysiological investigation in arhythmia or disturbance of impulse propagation
2.0
11.7
147
689
Z11
ICPC
Compliance/being ill problem
4.0
11.6
46
108
N06AX21
ATC
duloxetine; oral
1.6
11.6
300
1771
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
0.5
11.6
85
1582
NA1AD
NOMESCO Finland
Cervical spine CT examination
1.9
11.6
167
824
R03AK03
ATC
[D] fenoterol & other drugs for obstructive airway dis; inhalant
0.7
11.5
302
4106
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
0.6
11.5
205
3021
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
0.6
11.5
259
3629
SPAT1352
SPAT
Inspection, maintenance and instruction for use of hearing aid
2.1
11.5
128
570
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
0.7
11.5
561
6874
R01AD58
ATC
fluticasone, combinations; inhalant, nasal
0.6
11.5
190
2844
XKD00
NOMESCO Finland
Uroflowmetry
1.3
11.5
1038
7753
EB1AA
SPAT
NA
0.3
11.5
17
621
S22.3
ICD-10 Finland
Fracture of rib
1.6
11.4
307
1831
AAF20
NOMESCO Finland
Revision of shunt of ventricle of brain
5.1
11.3
35
64
JN4BD
NOMESCO Finland
Extensive body CT
0.7
11.3
275
3796
G04BD07
ATC
tolterodine; oral
1.6
11.2
325
1976
N18
ICPC
Paralysis/weakness
2.2
11.2
111
469
P99
ICPC
Psychological disorders other
3.9
11.1
45
108
F0021, G301
ICD-10 Finland
NA
+∞
11.1
11
*
AAD10
NOMESCO Finland
Evacuation of chronic subdural haematoma
2.2
11.1
111
473
G40.20
ICD-10 Finland
Complex partial seizures with only alteration of consciousness
3.4
11.1
53
146
G25.9
ICD-10 Finland
Extrapyramidal and movement disorder, unspecified
2.9
11.0
65
209
N05AH02
ATC
clozapine; systemic
6.1
11.0
29
44
WX100
NOMESCO Finland
Conjunctival surface anesthesia
0.7
11.0
428
5428
G31.1
ICD-10 Finland
Senile degeneration of brain, not elsewhere classified
11.0
10.8
20
17
L01BC06
ATC
capecitabine; oral
0.4
10.7
32
833
R03BB01
ATC
ipratropium bromide; inhalant
0.6
10.7
194
2845
T89
ICPC
Diabetes insulin dependent
2.3
10.7
95
384
L15
ICPC
Knee symptom/complaint
0.7
10.7
482
5978
R05
ICPC
Cough
0.7
10.7
487
6029
L03AA02
ATC
filgrastim; parenteral
0.3
10.7
16
582
N39.4
ICD-10 Finland
Other specified urinary incontinence
1.5
10.7
386
2466
4148X
ICD-9 Finland
Other forms of chronic ischaemic heart disease, Other specified forms of chronic ischaemic heart disease[MORBUS CORDIS ISCHAEMICUS ALIA,MÄÄRITTELEMÄT]
0.2
10.7
14
548
N99
ICPC
Neurological disease other
3.0
10.6
58
178
F09
ICD-10 Finland
Unspecified organic or symptomatic mental disorder
40.3
10.5
13
*
D07AA02
ATC
hydrocortisone; topical
1.4
10.5
503
3398
WX704
NOMESCO Finland
Intubation
0.5
10.5
83
1510
FP1B5
NOMESCO Finland
Resting ECG, 12 leads
2.6
10.5
77
280
UGC12
NOMESCO Finland
Flexible bronchoscopy
0.7
10.5
255
3516
G40.2
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
3.4
10.4
49
134
Y94.1
ICD-10 Finland
Accident in connection with service housing
11.1
10.3
19
16
SCA02
NOMESCO Finland
Analysis and advice of nutrition with regard to dentistry
1.6
10.3
251
1464
Z08
ICPC
Social welfare problem
3.2
10.3
52
151
N05AA02
ATC
levomepromazine; systemic
1.8
10.2
170
886
C34.3
ICD-10 Finland
Malignant neoplasm: Lower lobe, bronchus or lung
0.3
10.2
24
694
N39.9
ICD-10 Finland
Disorder of urinary system, unspecified
2.3
10.2
94
388
F06.2
ICD-10 Finland
Organic delusional [schizophrenia-like] disorder
+∞
10.1
10
*
A10BB12
ATC
glimepiride; oral
1.4
10.1
527
3614
F07.9
ICD-10 Finland
Unspecified organic personality and behavioural disorder due to brain disease, damage and dysfunction
102.3
10.1
11
*
L57.0
ICD-10 Finland
Actinic keratosis
0.7
10.0
388
4926
Z48.0
ICD-10 Finland
Attention to surgical dressings and sutures
0.4
10.0
33
820
L12
ICPC
Hand/finger symptom/complaint
0.7
10.0
244
3359
WF002
NOMESCO Finland
Radical radiotherapy
0.5
9.9
73
1358
R54
ICD-10 Finland
Senility
3.5
9.9
45
120
M01AC06
ATC
meloxicam; systemic, rectal
1.2
9.9
1379
10839
8000/3-C34.9
ICD-O-3
Neoplasm, malignant of lung, NOS
0.4
9.9
37
876
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
0.7
9.8
442
5486
R03AC02
ATC
salbutamol; inhalant
0.8
9.8
1669
17701
Z75.0
ICD-10 Finland
Medical services not available in home
5.4
9.7
28
48
C34.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of bronchus and lung
0.2
9.7
9
427
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
1.4
9.7
537
3721
8041/3-C34.9
ICD-O-3
Small cell carcinoma, NOS, of lung, NOS
0.1
9.6
6
370
WX111
NOMESCO Finland
Local infiltration anesthesia
0.3
9.6
27
722
J01CA04
ATC
amoxicillin; systemic
1.2
9.6
3338
28639
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
0.8
9.6
942
10565
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
0.4
9.5
52
1066
DFF00
NOMESCO Finland
Pure tone audiometry
0.6
9.5
202
2866
4289X
ICD-9 Finland
Heart failure, unspecified
0.2
9.5
6
366
A01
ICPC
Pain general/multiple sites
1.5
9.4
325
2056
S00.0
ICD-10 Finland
Superficial injury of scalp
2.1
9.4
101
446
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
0.4
9.3
42
925
N02AX02
ATC
tramadol; systemic, rectal
0.8
9.3
1586
16835
T36
ICD-10 Finland
Poisoning by systemic antibiotics
2.2
9.3
88
369
D07BA04
ATC
hydrocortisone and antiseptics; topical
1.4
9.3
370
2417
R03DA04
ATC
theophylline; systemic, rectal
0.7
9.3
268
3578
P28
ICPC
Limited function/disability (P)
4.7
9.3
30
59
SPAT1111
SPAT
Planning of analgesia
2.6
9.2
64
229
F01
ICD-10 Finland
Vascular dementia
5.8
9.2
25
40
C78.7
ICD-10 Finland
Secondary malignant neoplasm of liver and intrahepatic bile duct
0.3
9.1
26
690
Z01.9
ICD-10 Finland
Special examination, unspecified
1.6
9.1
210
1207
H02AB07
ATC
prednisone; oral
0.7
9.1
464
5660
F07.8
ICD-10 Finland
Other organic personality and behavioural disorders due to brain disease, damage and dysfunction
93.0
9.1
10
*
F00.02
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, presenile onset other additional symptoms, mainly illusions
93.0
9.1
10
*
N03AF02
ATC
oxcarbazepine; oral
2.0
9.1
108
498
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
1.6
9.1
214
1237
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
1.7
9.0
201
1145
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
0.4
9.0
33
787
NFB10
NOMESCO Finland
Primary partial prosthetic replacement of hip joint not using cement, other or unspecified
3.5
9.0
40
106
S32.8
ICD-10 Finland
Fracture of other and unspecified parts of lumbar spine and pelvis
2.4
8.9
71
273
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.2
8.9
1727
14011
L76
ICPC
Fracture: other
1.8
8.9
139
711
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
1.6
8.9
217
1269
L17
ICPC
Foot/toe symptom/complaint
0.8
8.8
701
8071
R29.6
ICD-10 Finland
Tendency to fall, not elsewhere classified
4.1
8.8
33
75
KMAK
NOMESCO Finland
NA
1.2
8.8
1489
11916
HA1RA
SPAT
NA
0.0
8.8
*
233
H01
ICPC
Ear pain/earache
0.6
8.8
121
1891
N05CF01
ATC
zopiclone; oral
1.2
8.8
1786
14554
I48.0
ICD-10 Finland
Paroxysmal atrial fibrillation
0.6
8.8
111
1772
G31.9
ICD-10 Finland
Degenerative disease of nervous system, unspecified
5.2
8.7
26
47
WW500
NOMESCO Finland
Blood transfusion
0.5
8.6
67
1221
J01MA02
ATC
ciprofloxacin; systemic
1.2
8.6
1982
16335
C03DA01
ATC
spironolactone; oral
0.7
8.5
418
5126
SDA04
NOMESCO Finland
Very demanding parodonthologic therapy
0.7
8.5
306
3936
F32.3
ICD-10 Finland
Severe depressive episode with psychotic symptoms
2.8
8.5
51
168
SPAT1294
SPAT
Other function in accordance with health social work nomenclature
1.8
8.4
132
678
T93
ICPC
Lipid disorder
0.5
8.4
79
1362
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
1.5
8.4
258
1595
SPAT1127
SPAT
Enema
2.5
8.4
64
240
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
1.6
8.3
227
1365
SPAT1097
SPAT
Recording of ECG
1.3
8.3
741
5508
S18
ICPC
Laceration/cut
0.8
8.3
1451
15408
C34.12
ICD-10 Finland
Malignant tumor of the anterior, bronchial or pulmonary adenocarcinoma
0.2
8.3
11
424
M05BA02
ATC
clodronic acid; systemic
0.0
8.3
*
224
YG1BD
NOMESCO Finland
Extensive CT examination of thorax for dose design of radiotherapy
0.4
8.2
26
660
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
0.8
8.2
701
8007
K03.82
ICD-10 Finland
Split tooth for reasons other than trauma
0.5
8.2
54
1039
C34.11
ICD-10 Finland
Malignant tumor of the anterior, bronchial or pulmonary epidermoid carcinoma
0.3
8.2
13
454
F01.24
ICD-10 Finland
Subcortical vascular dementia other additional symptoms of mixed type
83.7
8.2
9
*
SPAT1313
SPAT
Guidance and counselling related to accident prevention
3.1
8.1
43
131
F06.8
ICD-10 Finland
Other specified mental disorders due to brain damage and dysfunction and to physical disease
+∞
8.1
8
*
F0022, G301
ICD-10 Finland
NA
+∞
8.1
8
*
A23
ICPC
Risk factor NOS
1.7
8.1
159
875
I10
ICD-10 Finland
Essential (primary) hypertension
1.2
8.1
3374
29187
C34.10
ICD-10 Finland
Malignant tumor of the upper lobe, bronchus or lung without histology
0.3
8.0
16
499
ZX090
NOMESCO Finland
Other technic of radiotherapy
0.4
8.0
30
708
NF1BA
NOMESCO Finland
Hip extensive X-ray examination
1.6
8.0
182
1047
NE1AD
NOMESCO Finland
Pelvis and hip bones CT examination
1.9
7.9
106
515
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
0.6
7.9
113
1749
G04BD11
ATC
fesoterodine; oral
1.7
7.9
166
931
DJA10
NOMESCO Finland
Biopsy of septum of nose
10.0
7.9
15
14
D38.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Trachea, bronchus and lung
0.6
7.9
89
1457
XF606
SPAT
NA
6.2
7.8
20
30
D07BC01
ATC
betamethasone and antiseptics; topical
1.3
7.8
497
3521
ZYC01
SPAT
NA
1.7
7.8
141
757
P15
ICPC
Chronic alcohol abuse
2.8
7.8
47
156
J09
ICD-10 Finland
Influenza due to identified zoonotic or pandemic influenza virus
1.9
7.8
113
567
Z74.1
ICD-10 Finland
Need for assistance with personal care
15.9
7.7
12
7
Z60.9
ICD-10 Finland
Problem related to social environment, unspecified
4.7
7.7
25
50
T03
ICPC
Loss of appetite
4.7
7.7
25
50
G04BD10
ATC
darifenacin; oral
2.8
7.7
46
152
JN4AD
NOMESCO Finland
Body CT examination
0.6
7.6
161
2283
F32
ICD-10 Finland
Depressive episode
1.9
7.6
109
542
SPAT1165
SPAT
Peritoneal dialysis
5.6
7.6
21
35
S28
ICPC
Limited function/disability (S)
3.4
7.6
34
92
N83.2
ICD-10 Finland
Other and unspecified ovarian cysts
0.5
7.5
56
1036
XJH00
NOMESCO Finland
Transanal ultrasonography
1.3
7.5
455
3201
E44.1
ICD-10 Finland
Mild protein-energy malnutrition
12.1
7.5
13
10
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
0.8
7.4
755
8462
TPX10
NOMESCO Finland
Implantation of vascular injection port
0.4
7.4
24
600
F10.0
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Acute intoxication
0.2
7.4
8
348
I95.9
ICD-10 Finland
Hypotension, unspecified
2.0
7.3
86
397
M02AA07
ATC
piroxicam; topical
1.2
7.3
1772
14610
I69.1
ICD-10 Finland
Sequelae of intracerebral haemorrhage
2.2
7.3
72
310
WX110
SPAT
NA
0.3
7.3
20
537
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
0.5
7.3
60
1073
K04
ICPC
Palpitations/awareness of heart
0.5
7.2
67
1161
D07AC01
ATC
betamethasone; topical
1.2
7.2
1412
11427
SPAT1240
SPAT
Therapeutic discussion
1.6
7.2
185
1096
I21.2
ICD-10 Finland
Acute transmural myocardial infarction of other sites
0.2
7.2
7
322
F01.1
ICD-10 Finland
Multi-infarct dementia
74.4
7.2
8
*
L90.0
ICD-10 Finland
Lichen sclerosus et atrophicus
0.3
7.2
20
530
F10.73
ICD-10 Finland
Residual or late-onset psychosis caused by alcohol dementia
7.4
7.2
16
20
-1
ICD-10 Finland
NA
2.1
7.1
73
319
X59
ICD-10 Finland
Exposure to unspecified factor
1.3
7.1
621
4601
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.2
7.1
1315
10587
F0002, G300
ICD-10 Finland
NA
+∞
7.1
7
*
F02.89*G40.9
ICD-10 Finland
Dementia in epilepsy
+∞
7.1
7
*
F00.03
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, presenil onset other additional symptoms, mainly depression
+∞
7.1
7
*
F0010, G308
ICD-10 Finland
NA
+∞
7.1
7
*
F0289, G318
ICD-10 Finland
NA
+∞
7.1
7
*
T90
ICPC
Diabetes non-insulin dependent
1.2
7.1
1047
8244
WX892
NOMESCO Finland
Monitored bed care
0.7
7.1
177
2423
YL1BD
NOMESCO Finland
Extensive CT examination of pelvis for dose design of radiotherapy
0.4
7.0
26
616
G21.9
ICD-10 Finland
Secondary parkinsonism, unspecified
3.8
7.0
28
69
XF655
NOMESCO Finland
Measurement of heart muscle perfusion with exercise
0.5
7.0
61
1073
Z50.1
ICD-10 Finland
Other physical therapy
0.6
7.0
98
1521
WX212
NOMESCO Finland
Femoral plexus blockade
1.8
7.0
106
539
D07CA01
ATC
hydrocortisone and antibiotics; topical
1.3
7.0
493
3552
C34.31
ICD-10 Finland
Malignant tumor of the lower lobe, bronchus or lung epidermoid carcinoma
0.2
6.9
8
334
R03AK07
ATC
formoterol and budesonide; inhalant
0.8
6.9
385
4642
Z75.1
ICD-10 Finland
Person awaiting admission to adequate facility elsewhere
2.4
6.9
55
212
R45.5
ICD-10 Finland
Hostility
27.9
6.9
9
*
A05
ICPC
Feeling ill
1.7
6.9
146
824
S82
ICPC
Naevus/mole
0.7
6.9
230
2990
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
1.3
6.9
606
4499
EBA30
NOMESCO Finland
Excision of root of tooth
1.5
6.8
201
1231
N87
ICPC
Parkinsonism
2.2
6.8
63
263
S42.2
ICD-10 Finland
Fracture of upper end of humerus
1.5
6.8
207
1279
S72.2
ICD-10 Finland
Subtrochanteric fracture
2.2
6.8
63
264
K03.66
ICD-10 Finland
Tooth plaque
1.5
6.8
190
1151
SPAT1107
SPAT
Extensive external surface anaesthesia of skin with cream or gel
3.9
6.8
26
62
LAF11
NOMESCO Finland
Laparoscopic bilateral salpingo-oophorectomy
0.5
6.8
42
820
HA003
NOMESCO Finland
Radiotherapy after partial ablation of mammary gland
0.4
6.8
20
517
90621
NOMESCO Finland
NA
3.4
6.8
30
81
NJ2MA
NOMESCO Finland
Measurement of mechanical axis of lower leg with X-ray
0.6
6.8
140
1989
G04BD04
ATC
oxybutynin; oral, transdermal
1.4
6.7
329
2236
XG460
NOMESCO Finland
Short time oxymetry
0.4
6.7
35
726
201
Kela drug reimbursment
Chronic cardiac insufficiency
0.7
6.7
259
3290
A11CC03
ATC
alfacalcidol; systemic
0.4
6.7
34
711
R63.4
ICD-10 Finland
Abnormal weight loss
1.6
6.7
170
1006
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
1.4
6.7
294
1961
XF404
NOMESCO Finland
Ambulatory ECG
0.7
6.7
266
3360
K22
ICPC
Risk factor cardiovascular disease
0.6
6.6
110
1639
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.2
6.6
942
7386
B01AB10
ATC
tinzaparin; parenteral
0.6
6.6
132
1891
WZC30
NOMESCO Finland
Teaching
0.7
6.6
262
3316
M04AA01
ATC
allopurinol; systemic
0.8
6.6
619
7001
EB1SA
SPAT
NA
0.2
6.6
7
306
LCA06
NOMESCO Finland
Biopsy of endometrium
0.6
6.6
98
1498
N03AX18
ATC
lacosamide; systemic
5.2
6.6
19
34
I62.0
ICD-10 Finland
Nontraumatic subdural haemorrhage
2.3
6.6
56
226
S21
ICPC
Skin texture symptom/complaint
0.7
6.6
300
3715
WD115
NOMESCO Finland
Multiple cystostatic therapy of methastized malignancy
0.3
6.5
18
481
R44.1
ICD-10 Finland
Visual hallucinations
3.6
6.5
27
69
N06AX12
ATC
bupropion; oral
2.2
6.5
59
246
Z43.5
ICD-10 Finland
Attention to cystostomy
2.6
6.5
43
152
G04BD12
ATC
mirabegron; oral
1.3
6.5
499
3637
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.3
6.5
382
2675
K59.09
ICD-10 Finland
Constipation, unspecified
1.4
6.5
306
2068
N05AX12
ATC
aripiprazole; systemic
3.0
6.5
35
110
S20.2
ICD-10 Finland
Contusion of thorax
1.5
6.4
183
1114
L02BB03
ATC
bicalutamide; oral
0.6
6.4
123
1775
G04CA52
ATC
tamsulosin and dutasteride; systemic
1.3
6.4
536
3950
K40.9
ICD-10 Finland
Unilateral or unspecified inguinal hernia, without obstruction or gangrene
1.2
6.4
702
5347
S00.1
ICD-10 Finland
Contusion of eyelid and periocular area
2.1
6.4
68
303
SPAT1014
SPAT
Treatment of eyes
1.9
6.4
92
462
S29
ICPC
Skin symptom/complaint other
0.8
6.4
449
5253
A10AD05
ATC
insulin aspart; parenteral (insulins and analog. for injection, intermediate- or long-acting comb. with fast-acting)
1.7
6.4
135
763
Z03.8
ICD-10 Finland
Observation for other suspected diseases and conditions
1.5
6.4
189
1163
A27
ICPC
Fear of other disease NOS
1.5
6.4
178
1078
WX872
NOMESCO Finland
Intensive care
0.6
6.4
84
1321
F32.00
ICD-10 Finland
Mild depressive episode without somatic syndrome
1.9
6.4
83
400
A46
ICD-10 Finland
Erysipelas
1.2
6.4
694
5280
S32.0
ICD-10 Finland
Fracture of lumbar vertebra
1.6
6.4
151
881
N12
ICD-10 Finland
Tubulo-interstitial nephritis, not specified as acute or chronic
1.8
6.4
101
525
I27.9
ICD-10 Finland
Pulmonary heart disease, unspecified
0.1
6.4
*
225
R00.1
ICD-10 Finland
Bradycardia, unspecified
1.5
6.4
212
1340
S97
ICPC
Chronic ulcer skin
1.4
6.4
284
1901
L99
ICPC
Musculoskeletal disease other
1.9
6.3
81
390
R03BA02
ATC
budesonide; inhalant
0.8
6.3
453
5285
F32.1
ICD-10 Finland
Moderate depressive episode
2.0
6.3
70
319
S09.9
ICD-10 Finland
Unspecified injury of head
2.4
6.3
51
199
I64
ICD-10 Finland
Stroke, not specified as haemorrhage or infarction
2.5
6.3
48
182
H01BA02
ATC
desmopressin; nasal, systemic, sublingual
2.1
6.3
67
299
F02.89
ICD-10 Finland
Dementia in another specified disease that is classified elsewhere without information of additional symptoms
11.4
6.3
11
9
SPAT1243
SPAT
Psychiatric/psychological examination
3.0
6.3
33
102
F10.40
ICD-10 Finland
Withdrawal symptoms and delirium caused by alcohol without seizures
3.0
6.3
33
102
Z51.4
ICD-10 Finland
Preparatory care for subsequent treatment, not elsewhere classified
2.3
6.3
55
227
SPAT1285
SPAT
Provision of consultation response
1.5
6.3
218
1388
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
1.3
6.3
457
3307
S52.5
ICD-10 Finland
Fracture of lower end of radius
1.3
6.3
365
2553
AAF25
NOMESCO Finland
Removal of shunt of ventricle of brain
6.0
6.2
16
25
G45.0
ICD-10 Finland
Vertebro-basilar artery syndrome
1.6
6.2
157
931
ND1BA
NOMESCO Finland
Wrist extensive X-ray examination
1.9
6.2
82
402
F10.24
ICD-10 Finland
Alcohol depence active use
3.4
6.2
27
73
ICB03
NOMESCO Finland
Psychiatric treatment plan, monitoring
3.8
6.1
24
59
NH1BA
NOMESCO Finland
Ankle extensive X-ray examination
2.0
6.1
73
343
Z03.2
ICD-10 Finland
Observation for suspected mental and behavioural disorders
4.1
6.1
22
50
N05AN01
ATC
lithium; oral
2.4
6.1
47
180
IBZ07
NOMESCO Finland
Neurological assessment in psychiatry
13.3
6.1
10
7
UJF30
NOMESCO Finland
Ileoscopy through colon
0.7
6.1
165
2228
F99
ICD-10 Finland
Mental disorder, not otherwise specified
3.0
6.1
32
99
S01.41
ICD-10 Finland
Open wound in the temple-jaw region
2.6
6.1
40
141
WB113
NOMESCO Finland
Multiple adjuvant cytostatic therapy
0.4
6.1
25
564
Z00.0
ICD-10 Finland
General medical examination
1.2
6.1
739
5694
F0029, G301
ICD-10 Finland
NA
+∞
6.1
6
*
WD415
NOMESCO Finland
Demanding antibody therapy of methastized malignancy
0.2
6.1
5
253
110
Kela drug reimbursment
Parkinson's disease and comparable movement disrorders
1.6
6.1
146
855
IBZ01
NOMESCO Finland
Profession-specific psychiatric evaluation
5.7
6.1
16
26
C03EB01
ATC
furosemide and potassium-sparing agents; systemic
0.7
6.0
209
2704
G21.1
ICD-10 Finland
Other drug-induced secondary parkinsonism
4.9
6.0
18
34

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
3013
12300
2.79
307.65
2.2
1.8
1417.8
1145.8
nmol/l
37.41
2036
8938
269
136
17.48
295.53
1.0
1.0
533.5
700.4
ng/l
4.19
157
78
264
136
17.14
287.51
1.0
1.0
426.2
286.4
ng/l
4.29
162
81
2530
11969
2.20
204.71
5.5
4.8
0.0
0.0
estimate
0.88
608
3884
2410
11583
2.13
183.50
1.9
1.7
432.1
19423301.9
pmol/l
5.12
1784
9010
2947
16515
1.85
134.75
5.6
5.0
—
—
—
0
0
319
606
4.65
125.99
1.2
1.3
483.0
601.6
mg/l
4.03
285
579
281
504
4.91
118.69
1.3
1.4
290.3
896.2
e6/l
1.34
249
423
281
504
4.91
118.69
1.2
1.3
19.2
31.1
e6/l
0.32
243
404
3490
21269
1.73
114.53
5.0
4.7
58.2
89.6
ng/l
0.95
2866
17228
1367
6189
2.08
114.38
10.8
9.3
—
—
—
0
0
220
325
5.93
114.37
2.8
3.4
311.2
326.7
umol/l
0.65
159
265
279
523
4.69
111.88
1.2
1.2
4.0
3.9
mmol/l
0.14
262
481
1901
9746
1.88
110.81
6.0
4.9
1.0
1.0
kg/l
1.08
145
1674
471
10025
0.36
102.84
1.5
1.6
1.2
1.3
mmol/l
0.21
325
8152
1011
4382
2.12
93.41
4.2
3.7
—
—
—
0
0
2774
17058
1.61
78.80
2.4
3.2
2.3
2.4
mmol/l
2.34
2185
14126
1287
17454
0.56
76.95
2.1
2.4
—
—
—
0
0
220
483
3.98
72.12
1.2
1.3
—
—
—
0
0
2780
17537
1.55
68.10
5.1
4.1
—
5.9
—
0
12
4522
32068
1.49
60.93
6.6
5.7
3310.7
1623.6
e6/l
1.67
288
558
3266
21919
1.47
56.29
5.3
4.4
0.0
0.0
estimate
0.00
689
4175
850
11939
0.56
53.68
3.1
4.0
77.6
79.5
%
1.29
798
11652
1274
16123
0.61
53.54
3.2
3.9
11.9
10.1
mg/mmol
0.46
742
10184
1751
10430
1.56
52.59
3.0
3.0
2.5
2.5
mmol/l
6.68
1483
8853
1181
15149
0.61
52.24
2.6
3.2
358.2
345.4
mg/l
0.04
694
9716
3237
21923
1.45
51.77
6.3
6.0
0.0
0.0
estimate
0.00
663
4134
1189
15147
0.61
50.81
2.5
3.1
7.0
6.5
mmol/l
3.28
844
12168
3259
22214
1.44
49.68
5.4
4.5
0.0
0.0
estimate
0.50
664
4128
2787
18504
1.45
48.61
4.0
3.8
—
—
—
0
0
1059
5712
1.68
47.21
2.6
2.5
4.8
6.0
ug/l
1.50
686
4736
1829
20806
0.67
44.50
4.2
5.4
61.6
60.1
%
4.55
1558
18965
2523
16670
1.44
44.03
3.8
4.3
—
—
—
0
0
1846
20839
0.68
42.58
4.2
5.4
2.7
2.8
%
0.27
1574
18993
1790
20323
0.68
42.57
4.3
5.4
0.6
0.6
%
3.80
1523
18550
1861
20932
0.68
41.90
4.7
5.7
8.8
9.1
%
2.51
1593
19109
172
477
3.13
39.80
3.6
3.2
—
—
—
0
0
1923
21217
0.70
37.70
4.5
5.6
23.4
24.3
%
2.44
1633
19227
408
1750
2.05
37.61
2.8
3.9
3.9
3.9
mmol/l
0.10
342
1616
871
11230
0.62
37.11
4.3
4.5
152.7
495.0
ng/l
3.68
753
10161
629
8787
0.58
37.09
3.4
3.2
2.9
2.7
e6/l
0.39
399
4991
1376
15892
0.68
33.90
4.0
5.2
—
—
—
0
0
1744
11220
1.42
33.41
4.8
4.4
—
—
—
0
0
225
4194
0.44
32.59
1.2
1.3
—
—
—
0
0
119
2890
0.34
31.89
1.4
1.6
—
—
—
0
0
442
2070
1.88
31.54
2.8
3.6
1.5
1.5
mmol/l
0.00
434
2025
3838
37468
0.75
31.51
3.9
4.7
1.4
1.4
mmol/l
0.50
2970
32744
714
9311
0.62
31.27
2.9
3.0
1.9
1.4
e6/l
1.45
475
5465
2046
21788
0.73
30.22
3.8
5.1
0.6
0.6
e9/l
1.33
1723
18167
3909
37963
0.76
30.18
3.9
4.8
4.2
4.3
mmol/l
0.84
3055
33507
2068
21944
0.73
29.68
3.8
5.1
0.0
0.0
e9/l
2.41
1736
18340
2269
15571
1.35
28.53
2.3
2.1
249.0
217.8
u/l
0.85
2026
14389
4105
39395
0.77
27.51
4.2
5.5
2.4
2.4
mmol/l
1.10
3213
34617
353
5356
0.54
27.42
1.1
1.2
9.5
16.1
u/ml
1.56
127
1724
5312
41190
1.33
27.32
19.8
19.9
31.4
28.9
mg/l
4.64
4544
34924
1749
18842
0.73
27.01
11.7
10.8
0.0
0.0
e9/l
1.35
1489
15139
3138
22700
1.31
26.78
3.5
4.3
33.7
33.7
g/l
0.28
2642
20637
426
6081
0.58
26.53
1.4
1.4
—
—
—
0
0
2166
22564
0.75
26.43
3.9
5.2
0.2
0.2
e9/l
0.28
1774
19082
288
1238
2.03
26.39
3.8
3.9
32.0
30.3
mg/l
0.30
223
829
460
2319
1.74
25.69
3.4
4.4
—
—
—
0
0
803
4657
1.53
25.48
3.3
3.6
1.2
1.2
mmol/l
0.84
615
4029
3755
36260
0.78
25.14
3.5
4.2
1.2
1.2
mmol/l
0.20
2856
31298
85
203
3.61
24.95
1.2
1.3
—
—
—
0
0
692
3911
1.56
24.64
5.0
4.8
—
—
—
0
0
2152
22273
0.76
24.46
3.9
5.2
1.7
1.9
e9/l
2.11
1818
18895
171
3151
0.45
23.84
4.5
6.8
24.0
24.4
mmol/l
0.60
136
2862
465
6302
0.61
23.41
3.5
3.3
263.5
313.1
ng/l
1.59
417
5777
277
4308
0.53
23.24
2.2
2.4
28.3
36.4
u/l
4.44
216
3620
414
5726
0.60
22.60
1.1
1.2
51.4
42.4
iu/ml
0.38
105
1749
1112
12540
0.72
22.07
2.3
2.9
6384.4
7981.0
umol/l
0.43
800
10333
483
6332
0.63
20.94
2.5
3.6
33.1
26.6
ug/l
0.18
371
5311
165
2921
0.47
20.56
5.8
7.7
—
—
—
0
0
187
759
2.13
20.02
10.1
8.6
8.0
7.3
mmol/l
1.46
153
624
285
1343
1.84
19.97
9.4
13.6
—
—
—
0
0
477
6170
0.64
19.38
1.5
1.5
3.0
2.8
g/l
0.48
251
3292
304
4374
0.58
19.25
1.2
1.3
422.0
527.6
titre
0.62
60
1036
2575
25484
0.80
18.65
5.1
7.8
4.9
4.5
e9/l
8.03
2193
21758
2496
18206
1.25
17.69
2.1
2.2
77.4
81.3
nmol/l
7.96
1894
15455
538
3096
1.52
17.54
3.7
2.9
0.5
0.4
e6/l
0.51
530
3046
3309
31703
0.81
17.15
22.2
24.4
14.2
14.2
%
0.40
3138
30827
396
5166
0.64
16.62
2.3
2.5
13.3
10.4
umol/l
0.84
282
4459
1021
11207
0.74
16.29
4.3
6.2
—
—
—
0
0
5180
41070
1.24
16.11
21.0
19.5
—
—
—
0
0
5427
43248
1.24
16.09
23.5
24.4
139.7
139.3
mmol/l
11.84
5046
41916
1084
11768
0.75
15.96
2.2
2.5
—
—
—
0
0
2123
21209
0.80
15.92
4.2
4.4
—
—
—
0
0
483
5993
0.67
15.90
1.2
1.2
—
—
—
0
0
5429
43286
1.24
15.90
23.5
24.6
4.0
4.0
mmol/l
0.07
5030
41877
836
9424
0.73
15.89
1.3
1.3
—
—
—
0
0
5456
43535
1.24
15.80
27.5
29.3
7.5
7.2
e9/l
5.37
5047
41702
1142
12291
0.76
15.77
2.5
2.9
34.0
36.9
u/l
1.04
1011
11432
3162
23881
1.22
15.65
4.7
5.8
1.2
1.2
mmol/l
0.63
2570
21208
5451
43525
1.24
15.48
27.3
29.2
30.3
30.4
pg
2.68
5097
42424
5451
43526
1.24
15.47
27.4
29.2
91.9
92.1
fl
1.29
5100
42422
5451
43526
1.24
15.47
27.5
29.3
4.2
4.3
e12/l
26.39
5043
41683
5450
43519
1.24
15.46
27.4
29.3
237.5
235.1
e9/l
1.65
5063
41895
5451
43533
1.24
15.41
27.7
29.5
126.4
128.9
g/l
27.30
5097
42447
4095
31835
1.21
14.78
5.3
5.1
—
—
—
0
0
73
221
2.84
14.76
1.2
1.2
2.0
2.3
mmol/l
1.37
66
199
148
2424
0.51
14.64
1.3
1.2
—
—
—
0
0
158
2533
0.52
14.59
1.2
1.2
—
—
—
0
0
166
2592
0.54
14.06
1.5
2.2
3.7
3.7
g/l
0.01
86
1769
915
10002
0.75
13.93
2.8
3.5
0.9
0.9
ug/l
0.24
605
7381
437
5392
0.67
13.91
3.9
5.5
12.5
12.8
mmol/l
0.28
368
4997
118
2044
0.49
13.85
1.7
2.7
813.9
3363.8
u/ml
1.09
86
1721
158
2470
0.54
13.44
1.5
2.2
10.7
10.5
g/l
0.15
94
2009
603
3738
1.41
13.37
4.8
6.1
24.5
24.5
mmol/l
0.00
581
3493
1467
15026
0.80
13.21
3.3
3.5
0.7
0.6
e6/l
1.00
1237
11607
3199
30309
0.83
13.17
4.5
4.8
—
—
—
0
0
1520
10776
1.26
13.10
5.7
4.2
—
—
—
0
0
752
8351
0.74
12.69
2.3
2.6
19.5
20.5
%
1.17
518
6993
260
1364
1.65
12.62
3.8
4.5
2.7
3.0
mmol/l
0.77
172
915
260
1365
1.65
12.59
3.8
4.5
5.0
5.0
kpa
0.23
246
1321
76
258
2.53
12.40
1.3
1.2
—
—
—
0
0
218
3053
0.60
12.38
1.4
1.5
—
—
—
0
0
259
1368
1.64
12.26
3.8
4.5
7.8
8.2
kpa
2.67
244
1324
355
4447
0.67
12.18
1.2
1.3
—
—
—
0
0
285
1552
1.59
11.92
3.7
4.3
7.4
7.4
ph
0.74
246
1323
81
289
2.41
11.92
1.4
1.2
—
—
—
0
0
665
7445
0.74
11.81
3.5
4.8
1.0
1.1
mmol/l
0.55
530
6706
808
8800
0.76
11.80
2.1
2.5
2.2
2.2
g/l
1.68
616
7983
199
2772
0.60
11.07
2.5
3.4
24.0
24.1
mmol/l
0.11
161
2469
3840
30148
1.18
10.81
3.8
4.0
15.6
15.3
pmol/l
9.69
3079
26197
3412
26554
1.18
10.62
4.6
6.4
1.2
1.2
mmol/l
5.24
2430
22000
228
3045
0.63
10.61
1.3
1.4
—
—
—
0
0
67
1283
0.44
10.47
1.6
1.6
—
—
—
0
0
4169
38226
0.85
10.36
6.6
7.0
43.5
41.7
mmol/mol
16.02
3286
34001
413
4880
0.71
10.28
3.3
6.2
—
—
—
0
0
3680
28863
1.17
10.27
4.6
4.7
7.2
7.0
mmol/l
9.16
3431
27148
2921
22511
1.18
10.08
2.3
2.2
89.5
92.2
pmol/l
2.25
1453
11474
384
4575
0.70
10.03
1.3
1.4
—
—
—
0
0
79
1398
0.48
9.97
1.7
1.7
20.8
22.2
s
0.80
66
1281
83
325
2.20
9.94
1.4
1.7
—
—
—
0
0
134
2010
0.56
9.94
1.5
2.2
36.4
36.5
g/l
0.04
76
1641
153
2209
0.58
9.85
1.2
1.2
—
—
—
0
0
434
2683
1.41
9.80
1.6
1.8
3.2
2.3
ug/l
0.55
308
2266
132
618
1.84
9.65
1.0
1.2
—
—
—
0
0
116
1796
0.55
9.63
2.4
3.9
269.0
91.4
u/ml
1.25
106
1702
782
8333
0.78
9.51
2.1
2.6
0.8
0.8
mmol/l
1.04
639
7560
147
2114
0.59
9.33
1.2
1.5
—
20.3
—
0
49
1428
14229
0.83
9.30
3.3
3.5
—
—
—
0
0
58
1108
0.44
9.07
3.1
2.4
—
—
—
0
0
44
938
0.40
9.04
1.1
1.1
—
—
—
0
0
270
3344
0.68
8.75
1.6
1.6
1.6
1.5
g/l
0.67
178
2826
1980
14920
1.18
8.68
2.2
2.5
58.5
60.6
u/l
0.72
1727
13595
2033
15376
1.18
8.49
2.3
2.4
3.5
3.2
mg/l
4.53
1528
12897
1597
15632
0.84
8.40
2.3
2.6
—
—
—
0
0
162
2185
0.63
7.94
1.5
2.0
8.6
9.9
nmol/l
1.17
127
1792
10
444
0.19
7.91
1.3
1.5
—
—
—
0
0
140
1944
0.61
7.78
2.3
2.1
—
—
—
0
0
922
9431
0.81
7.68
2.1
2.5
10.6
11.3
umol/l
1.90
701
8550
171
2260
0.64
7.67
1.8
1.8
1.7
1.5
g/l
0.20
121
1976
40
127
2.70
7.59
3.0
2.7
26.0
29.9
umol/l
1.44
31
94
82
1304
0.53
7.54
1.1
1.1
1.0
1.0
u/ml
—
6
18
655
6933
0.79
7.45
1.2
1.2
1.6
1.7
u/ml
0.09
211
1606
818
8423
0.81
7.24
1.5
1.9
29.9
30.5
s
1.53
771
8149
312
3636
0.72
7.17
1.6
1.8
189.1
174.3
ug/g
0.26
196
2729
4571
36945
1.14
7.13
4.7
5.0
2.1
2.2
mu/l
1.24
3711
32333
21
46
3.91
7.13
1.0
1.1
14.8
60.6
%
—
8
18
227
2785
0.69
7.05
2.6
2.6
11.5
10.8
g/l
0.73
179
2496
130
1777
0.62
6.81
3.6
3.7
—
—
—
0
0
1280
9474
1.19
6.74
31.9
34.1
1.5
1.6
inr
0.25
116
1223
86
398
1.86
6.66
1.6
2.2
7.4
7.4
ph
0.43
17
166
114
1593
0.61
6.57
1.2
1.2
—
—
—
0
0
282
3287
0.72
6.51
2.6
2.6
—
—
—
0
0
5
239
0.18
6.26
1.0
1.5
—
—
—
0
0
60
974
0.52
5.99
1.4
1.6
12.5
12.8
mg/l
0.09
45
875
335
2160
1.34
5.94
1.3
1.3
—
—
—
0
0
16
33
4.15
5.88
1.7
2.8
124.2
133.4
nmol/l
0.18
11
27
1808
13877
1.15
5.88
1.6
1.6
20.2
20.0
nmol/l
0.09
1455
11565
273
3141
0.73
5.83
5.2
4.3
—
—
—
0
0
9
291
0.26
5.77
1.4
1.2
—
—
—
0
0
50
843
0.50
5.65
1.2
1.3
—
—
—
0
0
5
225
0.19
5.64
1.6
2.2
—
—
—
0
0
586
4093
1.24
5.60
3.1
4.0
—
—
—
0
0
27
83
2.79
5.52
1.1
1.3
—
—
—
0
0
223
2623
0.72
5.49
1.3
1.4
—
—
—
0
0
713
7246
0.82
5.49
1.7
1.9
—
—
—
0
0
975
9627
0.85
5.43
1.5
1.6
2.1
1.7
mg/l
1.40
721
7544
328
3635
0.76
5.41
3.0
3.5
0.6
0.6
%
0.05
65
893
66
1007
0.56
5.39
1.5
1.4
—
—
—
0
0
1094
8140
1.17
5.35
3.4
4.3
—
—
—
0
0
41
158
2.22
5.28
1.6
1.7
—
—
—
0
0
4414
39501
0.90
5.25
4.5
5.4
6.2
6.2
mmol/l
2.11
3395
34298
21
478
0.37
5.19
1.1
1.5
0.9
0.8
g/l
0.03
14
356
217
2534
0.72
5.13
1.3
1.4
—
—
—
0
0
98
511
1.65
5.13
1.3
1.2
293.0
308.6
nmol/l
0.27
62
369
50
815
0.52
5.13
1.1
1.1
80.0
82.8
titre
—
6
43
27
548
0.42
5.12
1.3
1.2
—
—
—
0
0
227
1414
1.38
5.07
3.3
3.8
—
—
—
0
0
23
495
0.40
5.02
1.1
1.3
41.9
47.8
mu/l
0.08
18
428
376
4052
0.78
5.00
3.2
3.6
1.1
1.0
%
0.25
107
1293
356
3862
0.78
5.00
3.2
3.6
0.2
0.1
%
0.54
97
1210
213
1317
1.39
4.98
2.5
2.7
15.8
15.4
%
0.61
81
713
17
413
0.35
4.87
1.1
1.1
—
—
—
0
0
82
1140
0.61
4.74
1.6
2.2
—
—
—
0
0
24
491
0.42
4.67
1.1
1.1
—
—
—
0
0
295
1944
1.31
4.58
1.8
2.1
760.2
550.5
ug/l
0.41
264
1842
54
827
0.55
4.54
1.1
1.1
—
1147.9
—
0
24
1519
11707
1.14
4.52
3.0
2.8
6.2
5.0
e6/l
2.56
1382
10254
24
484
0.42
4.52
1.0
1.0
—
—
—
0
0
61
902
0.57
4.52
1.4
1.5
—
—
—
0
0
89
1198
0.63
4.50
1.3
1.5
29.0
30.4
g/l
0.52
74
1051
82
1114
0.63
4.33
1.1
1.2
—
—
—
0
0
759
5579
1.18
4.31
4.4
4.6
—
—
—
0
0
9
247
0.31
4.25
1.0
1.2
—
—
—
0
0
77
1056
0.62
4.25
1.3
1.5
1328.0
1821.3
e6/l
0.72
61
776
32
123
2.23
4.21
1.5
1.3
—
—
—
0
0
40
653
0.52
4.20
3.7
3.3
—
—
—
0
0
14
344
0.35
4.16
1.0
1.4
10.6
10.2
%
0.10
14
344
141
841
1.44
4.11
1.7
1.9
27.8
33.4
umol/l
1.52
109
656
129
1578
0.69
4.09
1.2
1.2
330.7
225.5
u/ml
0.82
114
1422
55
811
0.58
4.07
1.4
1.5
—
—
—
0
0
25
474
0.45
4.06
1.1
1.3
—
—
—
0
0
65
917
0.60
4.05
1.4
1.6
—
—
—
0
0
529
5367
0.83
4.02
1.8
2.4
65.0
65.8
g/l
1.03
399
4706
26
483
0.46
4.01
1.3
1.3
—
—
—
0
0
15
349
0.37
3.99
1.0
1.2
—
77.5
—
0
14
10
284
0.30
3.97
1.1
1.7
158.7
184.4
pmol/l
—
10
254
40
633
0.54
3.83
3.6
3.5
53.3
61.2
%
0.57
18
376
30
520
0.49
3.82
1.5
1.2
—
—
—
0
0
25
461
0.46
3.80
1.1
1.3
213.9
240.7
pmol/l
0.29
20
352
71
964
0.63
3.79
1.3
1.5
55474.7
56477.4
e6/l
0.01
43
579
18
376
0.41
3.76
1.2
1.2
—
47.6
—
0
25
23
435
0.45
3.75
1.7
1.3
116.3
125.3
u/ml
—
7
88
337
3546
0.80
3.71
3.2
3.6
0.0
0.2
%
1.34
84
994
75
998
0.64
3.67
1.2
1.4
1.2
1.1
g/l
0.61
65
932
73
975
0.64
3.64
1.2
1.4
0.2
0.2
g/l
0.23
64
909
69
932
0.63
3.62
1.6
1.4
—
—
—
0
0
33
138
2.05
3.58
1.1
1.1
37.7
49.0
mg/l
1.10
26
113
54
765
0.60
3.48
1.2
1.4
6.4
6.5
mmol/l
0.15
43
713
22
409
0.46
3.45
1.0
1.3
—
—
—
0
0
27
466
0.49
3.43
1.3
1.3
—
—
nmol/l
—
0
0
1981
15726
1.10
3.40
3.0
3.9
7.4
7.4
ph
0.70
514
2975
33
532
0.53
3.40
1.1
1.2
—
—
—
0
0
23
85
2.32
3.36
3.3
2.5
0.3
0.4
u/field
0.70
23
85
144
1664
0.73
3.32
3.9
5.4
1.4
1.4
mmol/l
0.10
128
1477
13
294
0.38
3.31
1.1
1.2
—
112.3
—
0
13
97
1196
0.69
3.29
1.3
1.2
0.2
0.8
u/ml
1.83
12
126
53
742
0.61
3.28
1.6
2.3
—
—
—
0
0
5
161
0.26
3.27
1.0
1.1
—
—
—
0
0
449
4526
0.84
3.22
2.6
3.5
88.5
102.8
ng/l
2.37
286
3729
8
202
0.34
3.20
1.4
1.1
—
—
—
0
0
0
73
0.00
3.13
0.0
1.2
—
—
—
0
0
30
128
2.01
3.12
1.0
1.0
278.5
327.8
mg/l
0.78
23
111
31
134
1.98
3.11
1.2
1.4
101.4
79.9
umol/l
0.24
16
80
103
614
1.44
3.10
2.5
2.1
—
—
—
0
0
37
171
1.85
3.07
1.1
1.1
1.1
1.0
promille
0.16
22
126
183
2014
0.77
3.01
2.3
2.5
43.5
24.5
au/ml
—
5
39
50
690
0.62
2.95
1.3
1.1
—
—
—
0
0
39
572
0.58
2.94
1.6
1.7
—
—
—
0
0
13
277
0.40
2.93
1.0
1.3
—
—
—
0
0
12
34
3.02
2.89
1.8
1.3
—
—
—
0
0
213
2285
0.79
2.86
2.0
2.8
48.5
94.2
mg/l
1.13
155
1869
21
368
0.49
2.85
1.3
1.3
18.0
12.4
u/l
0.74
14
280
29
127
1.96
2.84
1.4
1.4
—
—
—
0
0
239
2524
0.80
2.80
3.3
4.4
0.9
0.9
%
0.04
228
2388
28
444
0.54
2.80
1.1
1.1
—
—
—
0
0
213
2278
0.79
2.80
2.0
2.8
69.5
57.3
mg/l
0.17
157
1866
52
699
0.63
2.76
1.7
1.4
—
—
—
0
0
10
232
0.37
2.75
4.6
1.7
70.7
69.4
%
—
10
214
75
933
0.68
2.74
1.2
1.2
25.7
44.0
u/l
1.95
55
788
25
404
0.53
2.67
1.1
1.1
358.5
320.3
u/ml
0.24
17
230
34
161
1.81
2.66
1.3
1.3
78.6
63.6
%
3.19
23
139
63
804
0.67
2.64
1.5
1.4
—
—
—
0
0
30
457
0.56
2.63
1.2
1.1
—
—
—
0
0
106
1233
0.73
2.63
1.7
1.6
31976.7
15451.8
e6/l
0.96
84
877
209
2219
0.80
2.60
2.0
2.8
3.9
3.0
ratio
0.24
21
156
17
308
0.47
2.57
1.0
1.0
—
—
—
0
0
522
5099
0.87
2.57
2.9
5.2
1.6
1.4
mmol/l
2.58
486
4829
26
114
1.95
2.56
2.3
2.0
56.0
51.5
umol/l
0.27
17
83
244
2541
0.81
2.54
3.5
4.4
1.5
1.5
%
0.18
232
2407
32
473
0.58
2.53
1.0
1.0
—
—
—
0
0
164
1785
0.78
2.53
1.3
1.3
47.7
61.6
au/ml
—
9
69
16
294
0.46
2.52
1.2
1.2
—
—
—
0
0
11
33
2.85
2.43
1.5
1.1
—
—
—
0
0
20
335
0.51
2.43
1.6
1.7
—
—
—
0
0
282
2881
0.83
2.42
1.3
1.4
—
—
—
0
0
67
388
1.48
2.42
1.7
1.4
—
—
—
0
0
265
2719
0.83
2.39
2.7
2.9
—
—
—
0
0
59
335
1.51
2.35
2.6
1.9
2.2
2.6
u/field
0.18
43
214
35
493
0.61
2.32
1.1
1.1
—
—
—
0
0
22
95
1.98
2.28
1.1
1.3
—
—
—
0
0
145
1579
0.78
2.28
1.1
1.1
69.3
126.5
iu/ml
1.47
56
510
2063
18629
0.93
2.26
2.6
3.0
158.0
159.5
ug/l
0.07
1621
16523
48
624
0.66
2.25
1.3
1.3
21.3
12.3
u/l
0.51
40
568
26
389
0.57
2.20
1.5
1.6
5.2
5.2
mg/l
0.01
19
365
129
855
1.29
2.11
2.3
3.3
62.1
60.4
%
0.67
129
855
106
1186
0.76
2.08
4.2
5.9
11.3
11.4
mmol/l
0.09
96
1066
106
1186
0.76
2.08
4.2
5.9
104.8
104.6
mmol/l
0.11
96
1066
8
166
0.41
2.06
1.6
2.2
—
—
—
0
0
622
5911
0.89
2.05
2.7
3.5
2.2
1.9
mmol/l
1.23
492
4705
129
1396
0.79
1.97
1.4
1.3
—
—
—
0
0
316
3134
0.86
1.97
4.1
5.7
24.5
24.8
mmol/l
0.85
304
3091
26
376
0.59
1.97
1.2
1.2
—
—
—
0
0
51
633
0.69
1.94
1.3
1.8
—
—
—
0
0
3893
34281
0.94
1.94
19.0
22.0
35.5
36.8
%
4.66
1342
19216
102
1132
0.77
1.92
1.5
2.7
217.6
959.0
u/ml
1.68
83
1025
32
436
0.63
1.91
1.4
1.4
—
—
—
0
0
82
519
1.35
1.88
1.2
1.3
274.4
274.0
mosm/kgh2o
0.05
60
360
9
169
0.45
1.85
1.6
2.3
—
—
—
0
0
627
5917
0.90
1.84
2.7
3.5
5.9
5.8
kpa
1.03
597
5700
2498
20451
1.07
1.83
3.3
3.4
2219.5
2349.6
ng/l
0.60
1964
17890
200
1424
1.21
1.80
2.2
2.4
123.6
124.1
g/l
0.09
181
1049
464
3529
1.13
1.79
1.6
2.0
393.1
386.5
nmol/l
0.28
369
3153
5
119
0.36
1.76
1.2
1.2
—
—
—
0
0
19
288
0.56
1.74
1.1
1.3
6.5
7.0
g/l
0.19
11
210
19
288
0.56
1.74
1.1
1.3
0.5
0.5
g/l
0.04
11
212
19
288
0.56
1.74
1.1
1.3
2.6
2.8
g/l
0.19
11
214
45
260
1.48
1.73
1.0
1.1
—
—
—
0
0
0
40
0.00
1.72
0.0
1.0
—
—
—
0
0
461
3521
1.13
1.68
3.5
6.9
0.8
0.7
%
11.42
455
3490
375
2830
1.14
1.66
2.2
2.5
0.7
0.7
%
4.50
358
2729
24
336
0.61
1.64
1.0
1.2
—
—
—
0
0
172
1220
1.21
1.64
1.2
1.2
—
—
—
0
0
29
154
1.61
1.62
1.1
1.0
115.1
137.6
nmol/l
1.97
29
154
14
59
2.03
1.60
1.2
1.1
1979.0
1537.0
miu/ml
0.53
14
59
20
290
0.59
1.58
1.3
1.3
—
—
—
0
0
5
12
3.56
1.58
1.4
1.0
—
—
—
0
0
20
289
0.59
1.57
1.4
1.6
—
—
—
0
0
12
48
2.14
1.56
1.5
1.1
—
—
—
0
0
7
137
0.44
1.55
5.1
1.7
4.4
8.7
%
—
7
128
0
36
0.00
1.54
0.0
1.1
—
—
—
0
0
0
37
0.00
1.54
0.0
1.1
—
—
—
0
0
429
3284
1.12
1.53
2.7
3.5
25.3
25.0
mmol/l
1.13
419
3186
37
461
0.68
1.50
1.2
1.3
—
—
—
0
0
12
49
2.09
1.49
1.5
1.1
—
—
—
0
0
4200
35049
1.05
1.48
5.0
7.4
83.9
84.6
u/l
0.22
3586
32568
184
1329
1.19
1.47
1.9
2.3
82.0
85.6
ug/min
0.04
77
758
2831
23387
1.05
1.47
12.0
12.6
1.3
1.4
inr
6.98
880
6191
11
44
2.14
1.43
1.5
1.0
—
—
—
0
0
28
364
0.66
1.42
1.0
1.1
—
—
—
0
0
25
333
0.64
1.42
3.4
3.3
—
—
—
0
0
96
1026
0.80
1.41
4.1
3.6
1.7
1.4
%
0.26
66
764
26
341
0.65
1.38
3.0
2.6
—
—
—
0
0
10
39
2.19
1.38
1.3
1.4
—
—
—
0
0
1022
9298
0.93
1.37
3.4
3.6
—
—
—
0
0
8
139
0.49
1.37
1.0
1.0
—
1.3
—
0
51
89
955
0.79
1.36
2.3
2.7
—
—
—
0
0
12
51
2.01
1.36
1.5
1.1
—
—
—
0
0
12
51
2.01
1.36
1.5
1.1
—
—
—
0
0
0
35
0.00
1.33
0.0
1.1
—
—
—
0
0
7
128
0.47
1.32
5.1
1.7
—
—
—
0
0
7
129
0.46
1.32
1.3
1.5
11.7
287.2
ug/l
—
7
120
6
20
2.57
1.32
1.0
1.0
—
—
—
0
0
6
113
0.45
1.29
1.0
1.4
29.7
29.9
umol/l
—
6
107
1896
15547
1.06
1.28
4.7
4.9
—
—
—
0
0
37
444
0.71
1.27
2.2
3.2
56.1
36.9
mg/l
0.39
27
337
8
135
0.51
1.26
1.1
1.2
—
0.3
g/l
—
0
9
10
164
0.52
1.26
3.0
1.9
—
—
—
0
0
8
136
0.50
1.25
4.0
5.6
—
—
—
0
0
5
102
0.42
1.25
1.2
1.4
96.6
134.5
ng/l
—
5
102
8
137
0.50
1.25
1.0
1.0
—
1.8
—
0
51
172
1714
0.85
1.25
2.1
2.9
—
—
—
0
0
136
1381
0.84
1.24
1.3
1.4
250.3
261.1
ug/g
0.26
70
860
10
163
0.52
1.24
2.0
1.6
—
—
—
0
0
744
6818
0.93
1.23
3.5
5.6
4.9
5.0
kpa
3.40
698
6396
744
6815
0.93
1.21
3.5
5.6
11.0
11.5
kpa
1.79
698
6391
5
16
2.67
1.21
1.2
1.1
—
—
—
0
0
484
4510
0.91
1.19
1.8
2.3
—
—
—
0
0
36
427
0.72
1.17
1.1
1.1
—
—
—
0
0
0
30
0.00
1.16
0.0
1.3
—
—
—
0
0
5
17
2.51
1.14
1.6
1.5
20.3
15.2
umol/l
—
5
17
10
158
0.54
1.13
1.4
1.7
830.0
21534.8
e6/l
—
5
94
11
168
0.56
1.12
1.5
2.0
—
—
—
0
0
73
497
1.26
1.10
1.2
1.4
199.2
316.5
titre
0.36
12
52
12
177
0.58
1.08
1.1
1.1
—
—
—
0
0
11
50
1.88
1.07
1.5
1.1
—
—
—
0
0
8
130
0.53
1.03
1.1
1.1
—
—
—
0
0
12
57
1.80
1.03
1.8
1.4
—
—
—
0
0
11
163
0.58
1.02
1.0
1.0
—
—
—
0
0
1853
16410
0.95
1.01
3.6
3.6
178.9
135.7
e6/l
0.29
1560
12843
7
30
2.00
0.99
1.1
1.1
—
—
—
0
0
46
300
1.31
0.99
1.6
2.1
19.0
22.3
umol/l
—
9
32
0
26
0.00
0.98
0.0
1.8
—
1.3
—
0
26
0
27
0.00
0.97
0.0
1.0
—
—
—
0
0
41
459
0.76
0.95
1.2
1.3
—
—
—
0
0
41
459
0.76
0.95
1.2
1.3
—
—
—
0
0
41
459
0.76
0.95
1.2
1.3
—
—
—
0
0
41
459
0.76
0.95
1.2
1.3
—
—
—
0
0
269
2078
1.11
0.92
3.7
3.2
0.8
0.8
nmol/l
0.21
189
1583
66
693
0.81
0.92
4.6
5.5
13.6
12.8
mg/l
0.55
53
619
59
626
0.80
0.90
1.4
1.4
78.0
64.6
%
2.76
40
404
5
87
0.49
0.90
1.0
1.5
—
—
—
0
0
5
89
0.48
0.90
1.0
1.0
—
2.1
—
0
10
21
122
1.47
0.88
1.3
1.5
19.0
16.5
pmol/l
0.73
11
91
30
346
0.74
0.87
1.0
1.1
—
12.6
—
0
7
58
401
1.24
0.82
1.1
1.1
31.1
35.2
mmol/l
0.90
44
328
24
283
0.72
0.82
4.7
4.3
—
—
—
0
0
22
263
0.71
0.81
4.9
4.5
—
—
—
0
0
0
21
0.00
0.80
0.0
1.1
—
—
—
0
0
0
21
0.00
0.80
0.0
1.1
—
—
—
0
0
2894
25283
0.97
0.80
3.6
5.6
12.5
12.9
umol/l
0.56
2503
23843
25
154
1.39
0.80
1.2
1.1
—
—
—
0
0
68
481
1.21
0.79
1.2
1.4
58.3
56.6
titre
—
6
38
0
23
0.00
0.78
0.0
1.0
—
—
—
0
0
0
24
0.00
0.77
0.0
1.9
—
1.7
—
0
15
705
5715
1.06
0.77
1.7
1.8
—
—
—
0
0
21
248
0.72
0.74
2.2
2.4
—
—
—
0
0
6
92
0.56
0.73
1.3
2.4
—
—
—
0
0
75
752
0.85
0.69
1.6
1.5
2.7
4.3
iu/l
2.08
22
196
12
155
0.66
0.68
1.0
1.2
—
—
—
0
0
15
185
0.69
0.68
1.1
1.1
—
—
—
0
0
30
331
0.77
0.68
1.3
1.6
50.7
68.4
%
1.21
18
264
5
23
1.86
0.68
1.0
1.0
—
—
—
0
0
419
3357
1.07
0.68
3.8
3.7
—
—
—
0
0
949
7796
1.05
0.65
2.3
2.2
1.8
1.8
%
0.17
686
6731
31
337
0.79
0.64
2.1
2.0
535.1
499.4
min
1.25
17
237
22
250
0.75
0.63
1.3
1.3
1030.7
146.0
ug/l
0.45
14
135
5
25
1.71
0.63
1.0
1.0
—
—
—
0
0
5
25
1.71
0.63
1.0
1.1
—
—
—
0
0
39
410
0.81
0.61
8.6
14.4
—
—
—
0
0
161
1518
0.90
0.61
2.5
3.0
7.3
7.7
kpa
2.65
150
1403
0
17
0.00
0.61
0.0
1.3
—
298.5
—
0
17
13
160
0.69
0.60
1.0
1.1
—
—
—
0
0
31
333
0.79
0.59
1.7
1.9
—
—
—
0
0
0
20
0.00
0.59
0.0
1.4
—
—
—
0
0
16
188
0.73
0.58
1.0
1.0
278.8
294.9
mg/l
—
10
163
48
342
1.20
0.57
1.1
1.2
—
—
—
0
0
173
1615
0.91
0.55
3.5
3.8
8.4
7.7
mmol/l
1.95
173
1582
3804
32084
1.03
0.55
3.6
4.4
17.0
16.8
mm/h
0.31
3126
28909
2103
18356
0.97
0.54
4.1
4.1
237.2
151.3
e6/l
1.26
1650
13609
60
595
0.86
0.52
1.1
1.1
—
—
—
0
0
21
232
0.77
0.52
1.0
1.5
47.3
71.4
mg/l
—
10
153
11
64
1.47
0.50
1.2
1.1
—
—
—
0
0
7
93
0.64
0.49
1.3
1.1
—
—
—
0
0
7
93
0.64
0.49
1.3
1.1
—
—
—
0
0
7
93
0.64
0.49
1.3
1.1
—
—
—
0
0
13
79
1.41
0.48
1.2
1.1
—
16.1
—
0
8
16
181
0.76
0.47
2.4
2.9
—
—
—
0
0
39
396
0.84
0.47
1.1
1.1
108.4
727.6
iu/ml
—
9
60
140
1095
1.09
0.47
1.2
1.2
—
—
—
0
0
81
620
1.12
0.42
2.7
2.4
2.4
2.1
u/field
0.23
45
193
0
13
0.00
0.41
0.0
2.2
—
—
—
0
0
0
14
0.00
0.41
0.0
1.5
—
—
—
0
0
0
14
0.00
0.41
0.0
1.6
—
—
—
0
0
12
138
0.74
0.41
1.0
1.2
1.4
1.4
mmol/l
—
6
84
0
16
0.00
0.40
0.0
1.1
—
17.7
—
0
8
94
884
0.91
0.39
2.9
2.7
—
—
—
0
0
18
121
1.27
0.38
1.3
1.4
26.2
18.3
%
—
10
92
2039
17715
0.98
0.37
4.3
5.9
4.7
6.0
ug/l
0.96
1611
15420
12
135
0.76
0.36
1.5
1.8
—
—
—
0
0
776
6826
0.97
0.36
3.4
5.6
1.4
1.1
mmol/l
1.13
570
5211
19
130
1.25
0.36
1.4
1.2
10.4
15.6
g/l
1.72
13
101
150
1195
1.07
0.36
1.3
1.3
63.6
60.4
mmol/l
0.50
115
947
29
293
0.85
0.36
1.4
1.5
2.4
2.7
%
0.10
20
237
6
37
1.39
0.35
1.0
1.1
—
—
—
0
0
6
37
1.39
0.35
1.0
1.1
—
—
—
0
0
6
37
1.39
0.35
1.0
1.1
—
—
—
0
0
34
249
1.17
0.34
1.7
1.8
9.1
9.1
mmol/l
0.02
28
201
727
6041
1.03
0.33
3.5
5.8
95.2
95.0
%
0.27
696
5781
6
77
0.67
0.33
1.0
1.6
—
—
—
0
0
609
5365
0.97
0.32
3.6
6.2
120.0
118.1
g/l
1.62
593
5178
821
7197
0.97
0.32
3.7
5.7
104.4
104.1
mmol/l
0.52
752
7022
12
132
0.78
0.32
1.1
1.1
—
—
—
0
0
61
470
1.11
0.31
1.4
1.4
11.6
26.8
%
10.17
42
302
308
2747
0.96
0.31
3.1
3.3
4.6
4.4
e9/l
0.44
152
1801
7
83
0.72
0.31
3.9
1.4
—
—
—
0
0
1300
11320
0.98
0.30
3.3
3.0
555.9
534.9
mosm/kgh2o
3.52
1130
9573
36
351
0.88
0.30
1.8
2.0
1.8
2.0
ug/l
0.14
27
291
4995
42434
1.02
0.30
8.4
11.4
21.8
22.7
u/l
0.81
4403
40197
664
5822
0.97
0.28
2.5
2.4
65.6
66.7
e9/l
0.34
515
4435
19
194
0.84
0.28
1.2
1.1
41.3
39.3
g/l
0.47
12
91
9
100
0.77
0.27
3.6
2.4
—
—
—
0
0
224
2000
0.96
0.26
2.7
3.0
4.2
4.2
pmol/l
0.02
173
1684
14
97
1.23
0.25
2.2
2.0
2.9
3.4
ug/l
—
7
39
15
105
1.22
0.25
1.6
1.2
—
—
—
0
0
26
255
0.87
0.25
1.2
1.3
3.9
3.3
mmol/l
0.55
21
231
9
65
1.18
0.24
1.2
1.2
1.3
1.4
ug/l
—
9
59
3582
30845
0.99
0.24
25.8
27.2
329.6
329.7
g/l
0.53
3408
30383
5
35
1.22
0.22
1.0
1.0
—
—
—
0
0
0
9
0.00
0.21
0.0
1.0
—
—
—
0
0
73
669
0.93
0.21
1.2
1.3
1.0
0.8
nmol/l
0.73
55
530
16
115
1.19
0.21
1.6
2.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
1708.2
—
0
11
124
1114
0.95
0.20
2.4
2.4
1.8
1.9
mg/l
0.37
98
959
6
43
1.19
0.19
1.8
1.2
—
—
—
0
0
53
487
0.93
0.18
1.8
2.1
692.0
611.1
ml
0.44
21
302
5
57
0.75
0.17
12.2
9.6
13.4
14.0
%
—
5
57
30
233
1.10
0.16
4.5
5.2
125.3
58.8
u/ml
—
7
68
37
343
0.92
0.16
1.9
2.6
7.6
7.3
mmol/l
0.41
24
222
312
2727
0.98
0.14
3.1
3.9
—
—
—
0
0
11
110
0.85
0.14
1.1
1.2
—
—
—
0
0
12
119
0.86
0.14
1.8
1.4
9.2
9.8
ug/l
0.09
12
104
30
279
0.92
0.14
1.6
1.5
—
—
—
0
0
525
4561
0.98
0.14
1.6
1.9
0.2
0.2
g/l
0.97
426
4143
577
4858
1.02
0.13
2.5
3.0
4.0
4.3
kpa
6.30
547
4658
72
590
1.04
0.11
2.5
2.6
—
—
—
0
0
81
719
0.96
0.10
1.2
1.3
—
—
—
0
0
204
1706
1.02
0.10
2.8
3.3
25.0
25.1
mmol/l
0.16
187
1488
454
3828
1.01
0.10
3.0
3.8
7.4
7.4
ph
1.48
75
498
25
198
1.08
0.10
3.2
5.8
24.5
24.6
mmol/l
0.01
20
180
17
159
0.91
0.09
1.6
1.5
—
—
—
0
0
459
3877
1.01
0.08
3.1
3.8
5.2
5.2
kpa
0.19
385
3532
5
53
0.81
0.08
1.0
1.1
—
0.4
—
0
20
25
228
0.94
0.08
1.1
1.4
2.6
3.7
%
—
10
54
87
722
1.03
0.08
1.2
1.2
—
—
—
0
0
151
1316
0.98
0.07
2.5
2.9
—
—
—
0
0
7
71
0.84
0.07
1.1
1.6
46.1
48.6
umol/l
—
7
71
21
192
0.93
0.07
1.0
1.4
17.9
21.4
%
0.25
15
158
19
151
1.08
0.06
1.7
1.7
—
—
—
0
0
23
209
0.94
0.06
1.2
1.3
1.1
1.1
nmol/l
0.01
11
158
259
2242
0.99
0.06
3.5
4.3
24.9
24.8
mmol/l
0.19
200
2016
226
1957
0.99
0.06
5.6
4.9
—
—
—
0
0
18
144
1.07
0.05
3.7
2.5
7.1
7.5
mmol/l
—
10
96
124
1042
1.02
0.05
2.7
2.6
4.2
4.1
mmol/l
0.22
124
1034
124
1042
1.02
0.05
2.7
2.6
106.9
105.3
mmol/l
1.99
124
1034
15
119
1.08
0.05
1.1
1.3
27.2
28.0
%
—
9
81
2630
22429
1.00
0.04
2.9
3.1
53.8
58.7
u/l
1.54
2132
19899
23
187
1.05
0.04
5.7
6.1
—
—
—
0
0
78
653
1.02
0.04
5.9
3.8
—
—
—
0
0
15
137
0.94
0.04
1.0
1.0
—
—
—
0
0
122
1029
1.01
0.03
2.7
2.7
—
—
—
0
0
225
1940
0.99
0.03
2.4
2.7
0.4
0.3
g/l
0.47
65
728
41
342
1.02
0.02
1.2
1.3
—
—
—
0
0
20
164
1.04
0.02
1.6
1.7
65.0
65.1
ug/l
0.00
20
157
170
1464
0.99
0.02
1.2
1.4
—
—
—
0
0
23
190
1.03
0.01
1.8
2.3
1603.6
1771.9
ml
0.24
14
150
16
137
1.00
0.00
1.0
1.0
—
—
—
0
0
12
102
1.01
0.00
1.1
1.2
—
—
—
0
0
11
94
1.00
0.00
1.0
1.1
—
—
—
0
0
23
199
0.99
0.00
1.0
1.1
—
—
—
0
0
42
357
1.01
0.00
1.2
1.4
—
—
—
0
0
25
211
1.01
0.00
1.1
1.3
—
—
—
0
0
439
3752
1.00
0.00
2.7
3.2
127.3
124.4
g/l
2.12
433
3657
56
483
0.99
0.00
1.3
1.3
210850.8
193457.8
e6/l
0.05
39
331
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
7
68
0.88
0.00
1.1
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
74.2
—
0
6
0
6
0.00
0.00
0.0
19.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
1.6
—
0
6
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
5
42
1.02
0.00
1.0
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
5.2
—
19.4
—
0
5
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

↥

Association

Association between endpoint F5_ALZHDEMENT and mortality.

Females

Parameter HR [95% CI] p-value
F5_ALZHDEMENT 2.398 [2.17, 2.65] < 0.001
Birth year 0.991 [0.98, 1.0] 0.03

During the follow-up period (1.1.1998 — 31.12.2019), 48483 out of 70483 females with F5_ALZHDEMENT died.

Males

Parameter HR [95% CI] p-value
F5_ALZHDEMENT 2.838 [2.47, 3.27] < 0.001
Birth year 0.988 [0.98, 1.0] 0.006

During the follow-up period (1.1.1998 — 31.12.2019), 27543 out of 38138 males with F5_ALZHDEMENT died.

Mortality risk

Mortality risk for people of age

years, who have F5_ALZHDEMENT.

N-year risk Females Males
1 0.185% 0.525%
5 1.168% 2.954%
10 3.006% 7.145%
15 5.373% 13.483%
20 9.032% 22.437%

Relationships between endpoints

↥

Index endpoint: F5_ALZHDEMENT – Dementia in Alzheimer disease

GWS hits: 16

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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