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Alzheimer’s disease (undefined)

DOID Endpoint Browser

AD_U

Alzheimer's disease: A progressive, neurodegenerative disease characterized by loss of function and death of nerve cells in several areas of the brain leading to loss of cognitive function such as memory and language.

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Endpoint definition

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Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — F009&G309
  • Cause of death: ICD-10 — F009&G309

2 out of 7 registries used, show all original rules.

514

4. Check minimum number of events

None

514

5. Include endpoints

None

514

6. Filter based on genotype QC (FinnGen only)

500

Control definitions (FinnGen only)

Control exclude
G6_ALZHEIMER

Extra metadata

First used in FinnGen datafreeze
DF2

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 500 219 281
Unadjusted period prevalence (%) 0.11 0.08 0.13
Median age at first event (years) 80.37 82.17 78.96

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
514
Matched controls
5140
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
307
Kela drug reimbursment
Tacrine, donepezil, rivastigmine, galantamine and other major and expensive drugs used to treat Alzheimer's disease
290.5
307.7
398
60
N06DX01
ATC
memantine; oral
39.0
307.7
279
152
N06DA02
ATC
donepezil; oral
39.3
307.7
249
120
G30.9
ICD-10 Finland
Alzheimer disease, unspecified
805.4
307.7
314
10
G30.1
ICD-10 Finland
Alzheimer disease with late onset
102.0
307.7
272
56
F009, G309,
ICD-10 Finland
+∞
307.7
508
*
F00.10*G30.1
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, senile onset without additional symptoms
85.8
266.4
143
23
N06DA03
ATC
rivastigmine; oral, transdermal
25.9
200.2
152
82
N05AX08
ATC
risperidone; systemic
12.4
164.6
209
270
G30.8
ICD-10 Finland
Other Alzheimer disease
58.1
116.2
66
13
F0019, G301,
ICD-10 Finland
+∞
110.5
102
*
N05AH04
ATC
quetiapine; oral
6.5
72.1
144
291
F00.9
ICD-10 Finland
Dementia in Alzheimer disease, unspecified
202.0
68.9
70
*
N06DA04
ATC
galantamine; oral
14.0
63.5
61
49
G30.0
ICD-10 Finland
Alzheimer disease with early onset
+∞
62.8
59
*
F03
ICD-10 Finland
Unspecified dementia
5.6
62.4
147
343
F0009, G300,
ICD-10 Finland
+∞
58.5
55
*
F00.20*G30.8
ICD-10 Finland
Dementia in Alzheimer's disease, atypical or mixed type without additional symptoms
17.4
57.9
49
31
P70
ICPC
Dementia
9.0
46.6
61
76
F00.10
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, senile onset without additional symptoms
62.7
44.3
51
9
F00.00*G30.0
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, presenile onset without additional symptoms
136.5
36.2
38
*
N06AB04
ATC
citalopram; systemic
3.0
27.4
159
663
G30
ICD-10 Finland
Alzheimer disease
45.3
24.8
30
7
N03AG01
ATC
valproic acid; systemic, rectal
6.5
24.1
41
68
N05BA04
ATC
oxazepam; oral
2.7
24.0
180
851
N05AH03
ATC
olanzapine; systemic
8.5
22.0
29
36
Z75.5
ICD-10 Finland
Holiday relief care
6.1
21.8
39
68
F0029, G308,
ICD-10 Finland
+∞
21.0
20
*
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
3.4
20.1
83
279
Z02.4
ICD-10 Finland
Examination for driving licence
0.1
19.9
6
641
N05AD03
ATC
melperone; systemic
4.8
18.6
44
99
WYA20
NOMESCO Finland
Home visit
5.2
15.7
33
67
N05AD01
ATC
haloperidol; systemic
3.8
15.4
50
143
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
3.5
14.4
52
160
R53
ICD-10 Finland
Malaise and fatigue
2.2
14.0
166
928
F00.19
ICD-10 Finland
Dementia in Alzheimer's disease with late onset without information about additional symptoms
+∞
13.6
13
*
N06AB10
ATC
escitalopram; oral
2.8
13.1
72
283
N05BA06
ATC
lorazepam; systemic, sublingual
3.3
12.9
52
171
R41.0
ICD-10 Finland
Disorientation, unspecified
3.5
11.9
42
127
S18
ICPC
Laceration/cut
0.3
11.5
40
1062
SPAT1251
SPAT
Organisation of medication
3.2
11.4
47
157
N02AJ06
ATC
codeine and paracetamol; systemic
0.2
11.3
12
655
A98
ICPC
Health maint/preventive medicine
0.5
10.7
150
2295
A06AD11
ATC
lactulose; oral
1.9
10.6
169
1034
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
3.5
10.2
35
104
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
3.3
9.8
37
117
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.8
9.6
216
1467
EBA15
NOMESCO Finland
Extraction of multiple teeth
4.4
9.5
24
57
N06AX11
ATC
mirtazapine; oral
1.9
9.4
147
888
F0014, G301,
ICD-10 Finland
+∞
9.4
9
*
N07AA05, ,
ATC
+∞
9.4
9
*
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
0.2
9.1
17
646
F00.00
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, presenile onset without additional symptoms
37.4
9.0
11
*
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.8
9.0
232
1632
H81
ICPC
Excessive ear wax
0.2
8.8
12
557
G91.2
ICD-10 Finland
Normal-pressure hydrocephalus
4.4
8.0
20
47
R23.8
ICD-10 Finland
Other and unspecified skin changes
0.2
7.9
8
377
E000001, ,
ATC
2.0
7.2
92
516
C04AE01
ATC
ergoloid mesylates; systemic
4.2
7.1
19
47
F06.7
ICD-10 Finland
Mild cognitive disorder
3.3
7.1
26
81
H13
ICPC
Plugged feeling ear
0.3
6.8
18
565
E78.0
ICD-10 Finland
Pure hypercholesterolaemia
0.2
6.8
8
345
SPAT1043
SPAT
Audiometry
0.2
6.7
7
324
SPAT1153
SPAT
Removal of sutures
0.4
6.7
30
727
130
Kela drug reimbursment
Malignant tumour
0.2
6.6
8
342
B01AF02
ATC
apixaban; oral
0.2
6.5
10
433
P20
ICPC
Memory disturbance
1.9
6.5
91
525
M79.6
ICD-10 Finland
Pain in limb
0.4
6.5
43
885
SPAT1245
SPAT
Provision of support and information to patient’s family members
2.4
6.4
43
187
3310A
ICD-9 Finland
Other cerebral degenerations, Alzheimer's disease
+∞
6.3
6
*
F009, G308,
ICD-10 Finland
+∞
6.3
6
*
DFF00
NOMESCO Finland
Pure tone audiometry
0.1
6.2
*
230
K03.82
ICD-10 Finland
Split tooth for reasons other than trauma
0.1
6.2
*
181
M25.5
ICD-10 Finland
Pain in joint
0.3
6.1
12
446
SPAT1137
SPAT
Taking care of patient’s/customer’s hygiene
2.0
6.1
68
363
F05.1
ICD-10 Finland
Delirium superimposed on dementia
8.7
6.1
12
14
351
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
0.3
6.0
22
588
L17
ICPC
Foot/toe symptom/complaint
0.3
6.0
20
559
F51.0
ICD-10 Finland
Nonorganic insomnia
0.1
6.0
*
177
Z71.8
ICD-10 Finland
Other specified counselling
0.3
6.0
16
501

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
73
1944
0.27
25.57
3.0
4.7
2.21
2.34
mmol/l
0.75
52
1648
68
1847
0.27
24.25
2.8
4.1
4.04
4.17
mmol/l
0.57
52
1583
68
1820
0.28
23.33
2.7
4.1
1.32
1.40
mmol/l
0.77
52
1539
66
1763
0.28
22.24
2.4
3.7
1.43
1.21
mmol/l
1.22
50
1475
96
2009
0.36
18.96
6.3
4.8
6.75
6.23
mmol/l
1.24
64
1698
97
1945
0.38
16.68
6.2
6.5
48.89
42.70
mmol/mol
2.81
72
1707
42
1251
0.28
15.86
6.5
6.2
4.79
4.68
e9/l
0.07
34
1049
76
1671
0.36
15.77
2.6
3.7
19.31
19.24
mm/h
0.01
62
1486
30
1036
0.25
14.40
2.9
4.1
0.58
0.66
e9/l
0.85
25
865
130
2226
0.44
14.39
6.0
9.5
19.74
23.21
u/l
1.21
107
2087
34
1090
0.26
14.36
3.4
4.2
0.17
0.20
e9/l
0.40
28
916
31
1044
0.25
14.23
2.9
4.1
0.04
0.04
e9/l
0.38
26
873
34
1078
0.27
14.04
2.9
4.5
1.52
1.68
e9/l
0.79
27
929
69
1524
0.37
14.02
3.9
4.6
—
—
—
0
0
61
1420
0.35
13.85
4.6
5.1
1.22
1.21
mmol/l
0.13
42
1148
105
1920
0.43
13.47
3.5
4.5
2.08
2.17
mu/l
0.21
79
1643
99
1845
0.43
13.27
4.6
6.0
88.86
85.53
u/l
0.22
81
1687
75
1552
0.39
12.86
4.0
4.2
7.92
7.05
mmol/l
1.90
68
1442
46
1191
0.33
12.80
2.0
2.2
99.70
87.82
pmol/l
1.21
22
619
33
998
0.28
12.27
2.6
2.8
128.33
153.50
ug/l
0.45
27
879
78
1554
0.41
12.01
3.2
3.6
15.30
15.32
pmol/l
0.02
62
1331
59
1311
0.38
11.66
4.4
4.5
12.36
13.33
umol/l
0.22
50
1222
54
1231
0.37
11.22
4.0
4.9
1.22
1.21
mmol/l
0.52
47
1075
52
1191
0.37
10.85
3.0
3.5
3283.16
3228.25
ng/l
0.02
38
1035
44
1071
0.36
10.42
1.7
2.7
—
—
—
0
0
35
945
0.32
10.24
3.9
4.8
—
—
—
0
0
35
927
0.33
9.80
10.8
10.8
0.00
0.01
e9/l
1.02
23
734
105
1752
0.50
9.35
16.8
24.0
15.54
15.63
%
0.05
91
1692
27
799
0.30
9.34
2.1
2.4
—
—
—
0
0
105
1741
0.50
9.10
4.8
5.2
—
—
—
0
0
149
2214
0.54
9.05
15.9
20.1
—
—
—
0
0
21
700
0.27
9.00
4.0
3.3
5.53
13.48
mg/mmol
1.65
11
451
63
1236
0.44
8.71
3.2
3.8
31.32
33.12
g/l
1.01
46
1111
18
622
0.26
8.16
2.3
2.7
53841.75
8328.12
umol/l
0.63
12
502
167
2352
0.57
7.98
19.1
29.6
123.29
125.02
g/l
0.68
143
2270
167
2351
0.57
7.96
18.9
29.3
36.31
36.60
%
0.16
129
2107
167
2351
0.57
7.96
18.8
29.3
4.10
4.16
e12/l
0.73
140
2232
167
2351
0.57
7.96
18.8
29.2
30.42
30.29
pg
0.28
144
2263
167
2351
0.57
7.96
18.8
29.2
92.22
92.05
fl
0.12
144
2264
167
2350
0.57
7.94
18.7
29.3
243.43
231.01
e9/l
1.06
141
2243
34
830
0.37
7.83
1.4
2.6
—
—
—
0
0
167
2341
0.58
7.75
16.0
25.3
4.05
4.06
mmol/l
0.12
142
2237
167
2340
0.58
7.73
15.8
25.1
140.15
139.19
mmol/l
2.23
143
2236
40
902
0.40
7.68
1.9
2.3
2.75
3.38
mg/l
1.49
29
756
21
636
0.30
7.47
3.2
2.7
6.52
6.03
mmol/l
0.37
15
504
43
923
0.42
7.29
2.4
2.6
2.36
2.35
mmol/l
0.23
28
778
22
642
0.31
7.28
3.1
2.7
97.10
309.72
mg/l
0.80
12
426
171
2354
0.59
7.18
18.6
29.3
7.70
7.40
e9/l
0.63
143
2228
163
2270
0.59
7.15
15.0
20.6
42.98
30.29
mg/l
1.93
128
1959
39
857
0.41
6.97
3.1
5.6
27.94
10.75
ug/l
0.35
34
737
37
830
0.40
6.95
3.7
3.4
7.42
7.40
ph
0.80
14
162
47
940
0.45
6.58
3.9
3.9
63.66
150.17
e6/l
0.57
37
759
113
1705
0.57
6.53
17.0
27.1
328.74
328.63
g/l
0.04
100
1652
41
861
0.43
6.51
2.1
2.0
339.93
281.45
u/l
0.21
30
788
11
444
0.23
6.42
1.8
1.8
30.71
29.90
s
0.31
11
429
39
830
0.43
6.39
3.7
3.9
0.80
0.61
e6/l
0.27
32
681
12
447
0.25
6.13
1.9
2.4
23.00
19.93
%
—
7
380
103
1570
0.57
6.07
17.6
24.4
1.54
1.52
inr
0.08
25
445
36
776
0.42
6.07
3.8
4.0
—
—
—
0
0
26
622
0.39
5.60
4.1
4.4
170.40
162.81
ng/l
0.02
21
578
13
439
0.28
5.60
2.4
3.7
—
—
—
0
0
16
479
0.31
5.51
1.8
2.2
2.23
2.19
g/l
—
9
427
21
545
0.36
5.41
6.0
5.3
—
—
—
0
0
26
605
0.40
5.24
2.9
2.9
2.48
2.48
mmol/l
0.05
14
505
6
261
0.22
5.23
1.2
2.1
63.67
65.16
g/l
—
6
226
60
1028
0.53
5.18
3.8
4.4
59.43
247.96
e6/l
1.93
38
806
43
821
0.48
5.18
3.7
4.9
—
—
—
0
0
7
277
0.24
5.17
1.1
1.5
—
—
—
0
0
36
727
0.46
5.07
1.6
1.8
450.59
443.64
pmol/l
0.05
22
576
0
127
0.00
4.94
0.0
1.5
—
—
—
0
0
5
229
0.21
4.68
1.0
2.0
—
—
—
0
0
7
261
0.26
4.57
3.9
4.1
—
—
—
0
0
75
1163
0.58
4.47
3.5
4.3
—
—
—
0
0
21
499
0.40
4.43
1.2
1.6
1.10
1.42
mg/l
0.64
16
395
39
732
0.49
4.43
4.7
3.6
552.41
521.34
mosm/kgh2o
0.74
34
629
7
254
0.27
4.42
1.6
4.6
1.64
1.57
mmol/l
—
7
239
7
258
0.26
4.41
1.3
1.3
—
—
—
0
0
87
1287
0.61
4.26
3.7
4.9
52.12
64.94
ng/l
0.48
59
1044
0
109
0.00
4.23
0.0
1.5
—
—
—
0
0
12
359
0.32
4.14
1.6
4.5
4.17
1.35
mmol/l
—
6
266
5
209
0.23
4.07
1.2
1.3
—
—
—
0
0
19
448
0.40
3.94
1.2
1.2
—
—
—
0
0
27
540
0.47
3.67
5.3
4.9
—
—
—
0
0
82
1189
0.63
3.60
4.7
5.2
0.00
0.00
estimate
-0.00
14
229
48
792
0.57
3.54
1.9
1.8
1395.31
1155.73
nmol/l
0.71
29
586
65
979
0.62
3.34
3.1
4.3
—
—
—
0
0
83
1174
0.65
3.21
5.9
7.1
0.00
0.00
estimate
-0.00
14
220
85
1186
0.66
3.06
4.6
5.1
0.00
0.00
estimate
-0.00
17
268
19
397
0.46
2.93
2.4
3.6
1.00
1.06
mmol/l
0.57
14
354
0
70
0.00
2.61
0.0
1.2
—
56.06
—
0
52
6
180
0.33
2.59
1.8
1.3
—
—
—
0
0
0
65
0.00
2.43
0.0
3.2
—
—
—
0
0
0
66
0.00
2.42
0.0
1.7
—
—
—
0
0
21
395
0.51
2.42
1.4
1.9
—
—
—
0
0
0
61
0.00
2.25
0.0
1.2
—
165.56
—
0
54
9
212
0.41
2.24
6.4
4.9
—
—
—
0
0
17
334
0.49
2.24
2.1
2.6
15.03
6.06
ug/l
—
10
263
8
199
0.39
2.21
1.5
1.9
0.18
0.18
g/l
—
8
171
7
181
0.38
2.20
2.3
2.8
—
—
—
0
0
5
142
0.35
1.90
2.0
3.2
—
—
—
0
0
0
53
0.00
1.88
0.0
1.0
—
—
—
0
0
5
137
0.36
1.77
2.2
4.3
—
—
—
0
0
0
47
0.00
1.71
0.0
1.1
—
—
—
0
0
6
148
0.40
1.66
2.3
6.5
93.25
93.80
%
—
6
148
0
44
0.00
1.52
0.0
1.4
—
—
—
0
0
14
254
0.54
1.50
3.8
4.0
—
—
—
0
0
8
166
0.47
1.49
1.4
1.2
—
—
—
0
0
5
16
3.14
1.44
1.2
1.1
—
—
—
0
0
11
208
0.52
1.36
2.5
4.5
—
—
—
0
0
0
37
0.00
1.35
0.0
1.4
—
56.78
—
0
37
0
37
0.00
1.35
0.0
1.0
—
—
—
0
0
0
39
0.00
1.34
0.0
1.2
—
3.54
—
0
5
0
34
0.00
1.16
0.0
1.2
—
14.06
—
0
27
0
35
0.00
1.15
0.0
2.3
—
—
—
0
0
22
327
0.66
1.12
1.5
1.8
—
—
—
0
0
14
231
0.60
1.11
1.7
3.0
—
—
—
0
0
0
31
0.00
0.96
0.0
1.1
—
—
—
0
0
0
31
0.00
0.96
0.0
17.4
—
—
—
0
0
54
665
0.79
0.88
4.3
4.9
—
—
—
0
0
0
24
0.00
0.79
0.0
1.7
—
—
—
0
0
0
25
0.00
0.79
0.0
1.7
—
—
—
0
0
0
26
0.00
0.78
0.0
1.1
—
—
—
0
0
0
26
0.00
0.78
0.0
1.3
—
—
—
0
0
0
26
0.00
0.78
0.0
2.5
—
60.93
—
0
20
0
28
0.00
0.76
0.0
3.9
—
29.21
—
0
23
6
106
0.56
0.73
3.2
4.1
—
—
—
0
0
7
42
1.68
0.68
2.3
1.6
—
—
—
0
0
10
155
0.64
0.67
6.8
5.4
—
—
—
0
0
0
21
0.00
0.60
0.0
1.4
—
22.56
—
0
21
0
23
0.00
0.58
0.0
1.1
—
—
—
0
0
0
23
0.00
0.58
0.0
2.2
—
7.43
—
0
9
8
123
0.64
0.55
1.1
1.3
—
—
—
0
0
8
126
0.63
0.55
2.6
3.6
—
—
—
0
0
47
543
0.85
0.45
4.6
5.6
1.01
1.01
kg/l
0.10
11
98
59
668
0.87
0.44
4.8
5.2
0.00
0.00
estimate
-0.00
14
208
0
15
0.00
0.41
0.0
1.6
—
9.75
—
0
15
0
15
0.00
0.41
0.0
1.7
—
6.01
—
0
15
0
16
0.00
0.41
0.0
1.2
—
—
—
0
0
0
16
0.00
0.41
0.0
1.0
—
—
—
0
0
0
16
0.00
0.41
0.0
1.0
—
—
—
0
0
0
16
0.00
0.41
0.0
1.5
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
2.3
—
9.68
—
0
16
0
17
0.00
0.40
0.0
1.1
—
—
—
0
0
0
17
0.00
0.40
0.0
1.2
—
3.89
—
0
17
0
17
0.00
0.40
0.0
1.1
—
—
—
0
0
0
18
0.00
0.40
0.0
1.2
—
0.58
—
0
13
0
19
0.00
0.39
0.0
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
5.8
—
—
—
0
0
0
11
0.00
0.21
0.0
1.3
—
1.18
—
0
11
0
11
0.00
0.21
0.0
2.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.7
—
349.60
—
0
10
0
10
0.00
0.21
0.0
1.2
—
5.40
—
0
5
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
2.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
2.8
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
40.40
—
0
5
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.4
—
—
—
0
0
5
43
1.16
0.21
1.6
2.1
86.84
88.45
%
—
5
43
0
13
0.00
0.21
0.0
1.4
—
—
—
0
0
0
13
0.00
0.21
0.0
1.3
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
18.33
—
0
9
0
14
0.00
0.20
0.0
1.5
—
28.15
—
0
14
6
78
0.77
0.15
1.0
1.2
—
—
—
0
0
5
44
1.14
0.10
4.2
2.7
72.00
62.70
%
—
5
44
5
45
1.11
0.10
2.4
2.6
—
—
—
0
0
9
86
1.05
0.07
3.1
5.2
—
—
—
0
0
21
220
0.95
0.03
5.0
5.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.5
—
129.25
—
0
8
0
5
0.00
-0.00
0.0
1.4
—
558.40
—
0
5
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
40.67
—
0
6
0
5
0.00
-0.00
0.0
1.4
—
0.84
—
0
5
8
88
0.91
-0.00
1.6
2.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
46.68
—
0
5
0
5
0.00
-0.00
0.0
7.8
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
5
53
0.94
-0.00
1.6
1.7
12844.00
25133.74
e6/l
—
5
38
0
5
0.00
-0.00
0.0
1.0
—
190.40
—
0
5
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
0.06
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
0.09
—
0
5
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
120.17
—
0
6
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
76.80
—
0
5
0
8
0.00
-0.00
0.0
3.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
2.26
—
0
6
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0

Mortality – FinRegistry

↥

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

↥

Index endpoint: AD_U – Alzheimer’s disease (undefined)

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).