No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
|
1. Apply sex-specific ruleNone |
- |
2. Check conditionsNone |
|
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
- |
4. Check minimum number of eventsNone |
- |
5. Include endpointsNone |
- |
6. Filter based on genotype QC (FinnGen only)None |
- |
Control definitions (FinnGen only)
- Control exclude
- G6_AD_STRICT, F5_DEMENTIA, F5_DEMENTIA_U, F5_PSYCH, NEURODIS, MEMLOSS, TRAUMBRAIN_NONCONCUS
Extra metadata
- First used in FinnGen datafreeze
- DF2
Similar endpoints
↥List of similar endpoints to
Alzheimer’s disease (undefined), excluding more controls
based on the number of shared cases.
Similar with more cases:
- Alzheimer’s disease (undefined)
- Dementia in Alzheimer disease
- Alzheimer disease
- Alzheimer disease, excluding more controls
- Degenerative diseases of the nervous system
Similar with less cases:
Case counts by codes
↥FinnGen case counts by registry codes:
No upset plot: script not run.
No upset table: script not run.
Summary Statistics
↥-FinRegistry-
This endpoint is excluded (different definition than used in FinnGen).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 500 | 219 | 281 |
| Unadjusted period prevalence (%) | 0.11 | 0.08 | 0.13 |
| Median age at first event (years) | 80.37 | 82.17 | 78.96 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 513
- Matched controls
- 4954
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
307
Kela drug reimbursment
Tacrine, donepezil, rivastigmine, galantamine and other major and expensive drugs used to treat Alzheimer's disease
+∞
307.7
398
*
G30.9
ICD-10 Finland
Alzheimer disease, unspecified
+∞
307.7
313
*
N06DX01
ATC
memantine; oral
589.5
307.7
279
10
F009, G309,
ICD-10 Finland
+∞
307.7
507
*
N05AX08
ATC
risperidone; systemic
57.0
307.7
209
59
G30.1
ICD-10 Finland
Alzheimer disease with late onset
1086.0
305.4
272
5
N06DA02
ATC
donepezil; oral
1145.3
277.1
249
*
F03
ICD-10 Finland
Unspecified dementia
94.3
269.7
147
21
N05AH04
ATC
quetiapine; oral
30.3
199.0
144
63
N06DA03
ATC
rivastigmine; oral, transdermal
2078.6
164.0
152
*
F00.10*G30.1
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, senile onset without additional symptoms
482.7
148.5
143
*
F0019, G301,
ICD-10 Finland
+∞
109.1
102
*
P70
ICPC
Dementia
41.7
96.9
61
16
N06AB04
ATC
citalopram; systemic
6.8
80.3
159
307
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
13.1
79.7
83
72
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
+∞
79.3
75
*
S06.0
ICD-10 Finland
Concussion
32.1
75.4
51
17
F00.9
ICD-10 Finland
Dementia in Alzheimer disease, unspecified
+∞
73.9
70
*
G30.8
ICD-10 Finland
Other Alzheimer disease
145.9
62.6
66
5
N06DA04
ATC
galantamine; oral
664.6
62.4
61
*
G30.0
ICD-10 Finland
Alzheimer disease with early onset
+∞
62.0
59
*
N05AD03
ATC
melperone; systemic
23.1
58.1
44
20
N05BA04
ATC
oxazepam; oral
4.8
57.9
180
505
F0009, G300,
ICD-10 Finland
+∞
57.7
55
*
F00.10
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, senile onset without additional symptoms
+∞
53.4
51
*
Z75.5
ICD-10 Finland
Holiday relief care
21.4
49.9
39
19
F00.20*G30.8
ICD-10 Finland
Dementia in Alzheimer's disease, atypical or mixed type without additional symptoms
87.1
44.1
49
6
R53
ICD-10 Finland
Malaise and fatigue
4.0
43.8
166
527
N06AB10
ATC
escitalopram; oral
7.1
43.5
72
112
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
121.7
42.9
46
*
F00.00*G30.0
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, presenile onset without additional symptoms
+∞
39.6
38
*
N06AX11
ATC
mirtazapine; oral
3.9
39.4
147
458
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
90.5
38.9
43
5
B01AC30
ATC
platelet aggregation inhibitors excl. heparin - combinations
9.4
38.8
49
55
N03AG01
ATC
valproic acid; systemic, rectal
107.4
37.8
41
*
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
+∞
36.4
35
*
R41.0
ICD-10 Finland
Disorientation, unspecified
10.2
35.5
42
43
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
3.2
35.4
216
913
WYA20
NOMESCO Finland
Home visit
14.7
35.4
33
23
G30
ICD-10 Finland
Alzheimer disease
+∞
31.2
30
*
P20
ICPC
Memory disturbance
4.3
30.5
91
238
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
6.5
30.1
52
84
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
9.5
30.0
37
40
N05AD01
ATC
haloperidol; systemic
6.8
29.9
50
78
N05BA06
ATC
lorazepam; systemic, sublingual
6.4
29.4
52
86
A06AD11
ATC
lactulose; oral
3.0
27.0
169
707
AA1AD
NOMESCO Finland
CT of head and brain
3.4
25.8
112
377
N05AH03
ATC
olanzapine; systemic
42.3
23.5
29
7
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.5
23.2
232
1213
I63.3
ICD-10 Finland
Cerebral infarction due to thrombosis of cerebral arteries
+∞
21.7
21
*
S06.5
ICD-10 Finland
Traumatic subdural haemorrhage
+∞
21.7
21
*
N04BA02
ATC
levodopa and decarboxylase inhibitor; oral
21.1
21.1
31
15
G91.2
ICD-10 Finland
Normal-pressure hydrocephalus
+∞
20.7
20
*
F0029, G308,
ICD-10 Finland
+∞
20.7
20
*
F05.9
ICD-10 Finland
Delirium, unspecified
74.0
19.5
22
*
Z02.4
ICD-10 Finland
Examination for driving licence
0.1
19.0
6
600
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.8
19.0
113
451
G20
ICD-10 Finland
Parkinson disease
+∞
18.6
18
*
F32.9
ICD-10 Finland
Depressive episode, unspecified
28.1
18.6
25
9
G45.1
ICD-10 Finland
Carotid artery syndrome (hemispheric)
190.1
18.4
19
*
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
6.4
18.2
31
49
SPAT1251
SPAT
Organisation of medication
4.4
17.9
47
110
G45.0
ICD-10 Finland
Vertebro-basilar artery syndrome
+∞
17.6
17
*
G40.9
ICD-10 Finland
Epilepsy, unspecified
+∞
17.6
17
*
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
+∞
17.6
17
*
B01AC07
ATC
dipyridamole; systemic
3.4
17.2
68
213
F06.7
ICD-10 Finland
Mild cognitive disorder
17.6
16.8
26
15
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.5
16.7
131
597
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.6
16.4
111
471
A10AB05
ATC
insulin aspart; parenteral
4.2
16.0
44
107
SPAT1245
SPAT
Provision of support and information to patient’s family members
4.2
15.5
43
105
G47.3
ICD-10 Finland
Sleep apnoea
23.4
14.9
21
9
110
Kela drug reimbursment
Parkinson's disease and comparable movement disrorders
+∞
14.5
14
*
S72.0
ICD-10 Finland
Fracture of neck of femur
3.2
14.4
60
194
N05CD07
ATC
temazepam; oral
2.4
14.2
116
534
R41.3
ICD-10 Finland
Other amnesia
20.0
13.6
20
10
F00.19
ICD-10 Finland
Dementia in Alzheimer's disease with late onset without information about additional symptoms
+∞
13.4
13
*
SPAT1137
SPAT
Taking care of patient’s/customer’s hygiene
2.9
12.9
68
252
R56.8
ICD-10 Finland
Other and unspecified convulsions
10.1
12.8
25
25
N05AA02
ATC
levomepromazine; systemic
5.3
12.7
26
49
N02BE01
ATC
paracetamol; systemic, rectal
2.0
12.5
349
2530
N03AF01
ATC
carbamazepine; oral, rectal
5.0
12.4
27
54
I63.4
ICD-10 Finland
Cerebral infarction due to embolism of cerebral arteries
+∞
12.4
12
*
F05.1
ICD-10 Finland
Delirium superimposed on dementia
+∞
12.4
12
*
F22.0
ICD-10 Finland
Delusional disorder
+∞
12.4
12
*
N06AB06
ATC
sertraline; oral
5.5
12.1
24
44
J01DB01
ATC
cefalexin; oral
1.9
12.0
299
2071
R55
ICD-10 Finland
Syncope and collapse
2.6
11.9
74
298
F01.9
ICD-10 Finland
Vascular dementia, unspecified
26.5
11.9
16
6
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
46.2
11.7
14
*
J01CA08
ATC
pivmecillinam; oral
1.9
11.4
200
1227
F00.00
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, presenile onset without additional symptoms
+∞
11.3
11
*
E86
ICD-10 Finland
Volume depletion
4.6
11.2
27
59
SAB01
NOMESCO Finland
Restricted oral and dental health check by dental hygienist or dental assistant
4.9
10.8
24
49
130
Kela drug reimbursment
Malignant tumour
0.2
10.8
8
444
E000001, ,
ATC
2.3
10.6
92
432
W19
ICD-10 Finland
Unspecified fall
2.9
10.3
50
177
EBA15
NOMESCO Finland
Extraction of multiple teeth
4.6
10.0
24
52
N30.0
ICD-10 Finland
Acute cystitis
2.4
9.8
72
313
N05AB03
ATC
perphenazine; systemic, rectal
16.5
9.7
15
9
N30.9
ICD-10 Finland
Cystitis, unspecified
3.1
9.7
42
139
N05CF01
ATC
zopiclone; oral
1.9
9.5
180
1119
I25.9
ICD-10 Finland
Chronic ischaemic heart disease, unspecified
2.0
9.4
119
646
I67.9
ICD-10 Finland
Cerebrovascular disease, unspecified
98.3
9.3
10
*
J01MA02
ATC
ciprofloxacin; systemic
1.8
9.3
196
1257
F0014, G301,
ICD-10 Finland
+∞
9.3
9
*
I64
ICD-10 Finland
Stroke, not specified as haemorrhage or infarction
+∞
9.3
9
*
N07AA05, ,
ATC
+∞
9.3
9
*
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
+∞
9.3
9
*
H02AA02
ATC
fludrocortisone; oral
17.3
9.3
14
8
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.8
9.1
176
1098
NFB20
NOMESCO Finland
Primary partial prosthetic replacement of hip joint using cement, other or unspecified
3.1
8.7
38
126
G56.0
ICD-10 Finland
Carpal tunnel syndrome
9.9
8.4
16
16
F00.20
ICD-10 Finland
Dementia in Alzheimer's disease, atypical or mixed type without additional symptoms
88.4
8.3
9
*
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
+∞
8.2
8
*
I65.2
ICD-10 Finland
Occlusion and stenosis of carotid artery
+∞
8.2
8
*
AAF05
NOMESCO Finland
Ventriculoperitoneal shunt
+∞
8.2
8
*
D07CA01
ATC
hydrocortisone and antibiotics; topical
2.3
7.9
61
271
-, ,
ICD-10 Finland
4.5
7.8
19
42
SPAT1254
SPAT
Administration of medicine
2.1
7.7
80
401
N06AX21
ATC
duloxetine; oral
4.0
7.7
22
55
N06CA01
ATC
amitriptyline and psycholeptics; systemic
2.9
7.7
37
130
N02AJ06
ATC
codeine and paracetamol; systemic
0.2
7.7
12
495
R42
ICD-10 Finland
Dizziness and giddiness
2.0
7.6
97
525
SAD01
NOMESCO Finland
Assessment of need for oral health care, standard
3.3
7.6
29
89
C04AE01
ATC
ergoloid mesylates; systemic
6.3
7.6
19
30
N06AA09
ATC
amitriptyline; systemic
2.9
7.5
36
126
X59
ICD-10 Finland
Exposure to unspecified factor
2.3
7.5
56
246
N05BA01
ATC
diazepam; systemic, rectal
2.2
7.5
66
311
S18
ICPC
Laceration/cut
0.4
7.4
40
858
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.2
7.3
69
333
G72.8
ICD-10 Finland
Other specified myopathies
78.4
7.3
8
*
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.0
7.3
91
489
A10AE04
ATC
insulin glargine; parenteral
2.6
7.2
44
175
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
+∞
7.2
7
*
30320
ICD-8 Finland
Alcoholism, Alcoholic addiction
+∞
7.2
7
*
I63.0
ICD-10 Finland
Cerebral infarction due to thrombosis of precerebral arteries
+∞
7.2
7
*
2900A
ICD-9 Finland
Senile and presenile organic psychotic conditions, Senile dementia, uncomplicated
+∞
7.2
7
*
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
10.7
7.2
13
12
S72.1
ICD-10 Finland
Pertrochanteric fracture
2.9
7.1
33
114
S70.0
ICD-10 Finland
Contusion of hip
3.2
7.0
28
88
A98
ICPC
Health maint/preventive medicine
0.6
7.0
150
2054
N06AA12
ATC
doxepin; systemic
3.0
6.9
31
105
E78.0
ICD-10 Finland
Pure hypercholesterolaemia
0.2
6.8
8
333
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
0.3
6.8
17
530
J69.0
ICD-10 Finland
Pneumonitis due to food and vomit
4.3
6.7
17
39
K90
ICPC
Stroke/cerebrovascular accident
16.4
6.6
10
6
H81
ICPC
Excessive ear wax
0.2
6.6
12
452
R23.8
ICD-10 Finland
Other and unspecified skin changes
0.2
6.5
8
324
-2, ,
ICPC
7.7
6.5
14
18
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.0
6.4
75
392
I95.1
ICD-10 Finland
Orthostatic hypotension
3.1
6.4
26
83
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.0
6.4
72
372
P72
ICPC
Schizophrenia
68.3
6.3
7
*
M02AA07
ATC
piroxicam; topical
1.6
6.3
181
1235
SPAT1104
SPAT
Monitoring of emergency patient
2.8
6.2
30
106
M01AH02
ATC
rofecoxib; oral
2.0
6.2
68
348
F02.39*G20
ICD-10 Finland
Dementia in Parkinson's disease without information on additional symptoms
+∞
6.2
6
*
AAF20
NOMESCO Finland
Revision of shunt of ventricle of brain
+∞
6.2
6
*
F10.9
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Unspecified mental and behavioural disorder
+∞
6.2
6
*
I61.9
ICD-10 Finland
Intracerebral haemorrhage, unspecified
+∞
6.2
6
*
G40.20
ICD-10 Finland
Complex partial seizures with only alteration of consciousness
+∞
6.2
6
*
30041
ICD-8 Finland
Neuroses, Depressiva
+∞
6.2
6
*
F10.29
ICD-10 Finland
Addiction caused by alcohol UNS
+∞
6.2
6
*
AAA20
NOMESCO Finland
Insertion of intraventricular pressure monitoring device
+∞
6.2
6
*
G31.9
ICD-10 Finland
Degenerative disease of nervous system, unspecified
+∞
6.2
6
*
I63.1
ICD-10 Finland
Cerebral infarction due to embolism of precerebral arteries
+∞
6.2
6
*
F10.49
ICD-10 Finland
Withdrawal symptoms and delirium caused by alcohol without information about seizures
+∞
6.2
6
*
G21.9
ICD-10 Finland
Secondary parkinsonism, unspecified
+∞
6.2
6
*
F009, G308,
ICD-10 Finland
+∞
6.2
6
*
3310A
ICD-9 Finland
Other cerebral degenerations, Alzheimer's disease
+∞
6.2
6
*
G91.9
ICD-10 Finland
Hydrocephalus, unspecified
+∞
6.2
6
*
F10.73
ICD-10 Finland
Residual or late-onset psychosis caused by alcohol dementia
+∞
6.2
6
*
G91.0
ICD-10 Finland
Communicating hydrocephalus
+∞
6.2
6
*
3540A
ICD-9 Finland
Mononeuritis of upper limb and mononeuritis multiplex, Carpal tunnel syndrome
+∞
6.2
6
*
G45.3
ICD-10 Finland
Amaurosis fugax
+∞
6.2
6
*
D07BC01
ATC
betamethasone and antiseptics; topical
2.2
6.2
52
240
J01EA01
ATC
trimethoprim; systemic
1.7
6.2
148
965
NFJ54
NOMESCO Finland
Internal fixation of fracture of upper femur with intramedullary nail
3.3
6.1
23
70
SPAT1216
SPAT
Assessment of functional ability
2.0
6.1
71
371
SPAT1053
SPAT
Memory test
2.0
6.1
67
343
SPAT1229
SPAT
Assessment of need for aid
2.5
6.0
39
160
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
73
1750
0.30
21.09
3.0
4.5
2.21
2.44
mmol/l
1.83
52
1466
68
1673
0.30
20.45
2.8
3.9
4.04
4.27
mmol/l
1.38
52
1421
68
1644
0.31
19.51
2.7
3.9
1.32
1.41
mmol/l
0.85
52
1370
66
1584
0.31
18.35
2.4
3.5
1.43
1.20
mmol/l
1.22
50
1312
96
1833
0.39
15.63
6.2
4.7
6.75
6.15
mmol/l
1.51
64
1506
42
1116
0.31
13.23
6.5
6.6
4.79
4.73
e9/l
0.04
34
923
97
1724
0.44
12.29
6.2
6.3
48.89
41.95
mmol/mol
3.36
72
1473
102
1760
0.45
11.80
13.5
18.0
62.52
60.45
ml/min/173m2
0.41
70
1406
130
2038
0.49
11.33
6.0
9.1
19.74
21.34
u/l
0.54
107
1883
76
1430
0.43
10.77
2.6
3.6
19.31
19.84
mm/h
0.07
62
1252
99
1645
0.48
9.76
4.6
6.1
88.86
91.30
u/l
0.15
81
1481
105
1705
0.49
9.64
3.5
4.1
2.08
2.22
mu/l
0.36
79
1403
33
848
0.33
9.26
2.6
2.7
128.33
158.37
ug/l
0.57
27
724
61
1186
0.43
9.07
4.6
5.3
1.22
1.21
mmol/l
0.37
42
966
46
1005
0.39
9.07
2.0
2.0
99.70
90.20
pmol/l
0.88
22
511
59
1145
0.43
8.67
4.4
4.9
12.36
14.24
umol/l
0.49
50
1058
31
792
0.34
8.52
1.9
2.0
77.58
80.58
nmol/l
0.26
19
638
21
656
0.28
8.49
4.0
3.4
5.53
12.54
mg/mmol
1.36
11
400
44
932
0.40
7.93
1.7
2.7
—
—
—
0
0
14
528
0.24
7.78
2.1
2.4
—
—
—
0
0
52
1012
0.44
7.53
3.0
3.2
3283.16
3025.48
ng/l
0.10
38
864
54
1029
0.45
7.38
4.0
4.7
1.22
1.20
mmol/l
1.00
47
904
78
1293
0.51
7.09
3.2
3.4
15.30
15.42
pmol/l
0.15
62
1075
75
1251
0.51
6.92
4.0
3.7
7.92
7.08
mmol/l
1.80
68
1158
105
1579
0.55
6.88
16.8
21.9
15.54
15.31
%
0.14
91
1521
18
541
0.30
6.70
2.3
2.7
53841.75
11206.95
umol/l
0.58
12
435
39
749
0.46
5.27
3.1
5.8
27.94
7.21
ug/l
0.46
34
642
167
2123
0.64
5.08
19.1
25.8
123.29
125.71
g/l
1.09
143
2033
167
2122
0.64
5.06
18.8
25.7
4.10
4.19
e12/l
1.18
140
1988
167
2121
0.64
5.04
18.9
25.7
36.31
36.51
%
0.10
129
1872
167
2121
0.64
5.04
18.7
25.6
243.43
234.16
e9/l
0.70
141
2002
63
1019
0.54
5.02
3.2
4.0
31.32
32.72
g/l
0.70
46
896
12
383
0.29
4.97
1.9
2.4
23.00
19.07
%
—
7
318
40
743
0.48
4.90
1.9
2.3
2.75
3.45
mg/l
1.72
29
593
53
894
0.52
4.83
2.9
2.6
54.91
67.87
u/l
0.44
43
768
167
2108
0.65
4.82
16.0
21.9
4.05
4.04
mmol/l
0.16
142
1996
167
2107
0.65
4.80
15.8
21.7
140.15
139.02
mmol/l
2.89
143
1995
26
544
0.43
4.38
4.1
4.0
170.40
198.45
ng/l
0.09
21
498
16
409
0.36
4.29
1.8
2.2
2.23
2.22
g/l
—
9
362
0
105
0.00
4.25
0.0
1.8
—
—
—
0
0
43
728
0.53
3.92
2.4
3.3
2.36
2.35
mmol/l
0.23
28
589
39
680
0.52
3.91
3.7
3.3
0.80
0.59
e6/l
0.32
32
521
32
593
0.49
3.86
2.7
5.1
25.59
23.29
%
0.29
19
334
0
91
0.00
3.72
0.0
1.8
—
3.42
—
0
73
21
448
0.43
3.71
1.2
1.5
1.10
1.88
mg/l
1.83
16
345
163
1998
0.69
3.71
15.0
17.6
42.98
32.31
mg/l
1.46
128
1665
7
218
0.30
3.41
1.6
3.9
1.64
1.52
mmol/l
—
7
208
0
84
0.00
3.35
0.0
2.0
—
1.35
—
0
65
12
310
0.36
3.32
2.0
4.5
100.83
103.95
mmol/l
1.26
12
310
0
79
0.00
3.17
0.0
1.6
—
35.15
—
0
61
37
614
0.55
3.14
1.8
2.0
—
—
—
0
0
59
859
0.62
3.02
3.5
3.2
—
—
—
0
0
12
295
0.38
2.99
1.6
4.3
4.17
1.30
mmol/l
—
6
223
0
70
0.00
2.81
0.0
1.7
—
0.00
—
0
60
0
71
0.00
2.81
0.0
1.7
—
0.30
—
0
61
26
463
0.52
2.79
2.9
3.3
2.48
2.48
mmol/l
0.02
14
375
11
263
0.39
2.60
1.8
1.7
30.71
30.51
s
0.06
11
250
0
69
0.00
2.59
0.0
1.7
—
0.00
—
0
60
26
447
0.54
2.50
1.9
1.8
—
—
—
0
0
7
176
0.38
2.20
2.0
1.6
—
—
—
0
0
103
1254
0.74
1.98
17.6
23.7
1.54
1.61
inr
0.24
25
323
36
531
0.63
1.96
1.6
1.8
450.59
13835392.79
pmol/l
0.50
22
412
19
322
0.55
1.78
2.4
3.8
1.00
1.08
mmol/l
0.81
14
282
7
154
0.43
1.57
1.1
1.4
—
—
—
0
0
82
978
0.77
1.33
4.7
4.1
0.00
0.00
estimate
-0.00
14
163
20
301
0.63
1.24
1.9
1.7
—
—
—
0
0
0
32
0.00
1.17
0.0
1.2
—
—
—
0
0
0
32
0.00
1.17
0.0
1.1
—
—
—
0
0
0
32
0.00
1.17
0.0
1.1
—
1.66
—
0
7
0
33
0.00
1.16
0.0
3.7
—
—
—
0
0
83
964
0.80
1.09
5.9
5.9
0.00
0.00
estimate
-0.00
14
156
0
30
0.00
0.97
0.0
1.5
—
—
—
0
0
0
30
0.00
0.97
0.0
1.0
—
—
—
0
0
0
31
0.00
0.95
0.0
1.2
—
—
—
0
0
0
31
0.00
0.95
0.0
1.4
—
267.81
—
0
31
0
31
0.00
0.95
0.0
1.2
—
—
—
0
0
0
31
0.00
0.95
0.0
1.6
—
—
—
0
0
0
31
0.00
0.95
0.0
1.2
—
—
—
0
0
0
31
0.00
0.95
0.0
1.2
—
—
—
0
0
0
31
0.00
0.95
0.0
1.2
—
—
—
0
0
48
582
0.78
0.91
1.9
1.8
1395.31
1099.88
nmol/l
0.94
29
413
41
507
0.76
0.90
2.1
1.6
339.93
178.25
u/l
0.81
30
452
85
964
0.82
0.89
4.6
4.1
0.00
0.00
estimate
-0.00
17
202
22
297
0.70
0.85
2.0
1.6
—
—
—
0
0
0
23
0.00
0.79
0.0
1.5
—
—
—
0
0
0
24
0.00
0.79
0.0
1.3
—
—
—
0
0
0
26
0.00
0.78
0.0
1.2
—
—
—
0
0
0
27
0.00
0.76
0.0
1.0
—
—
—
0
0
0
27
0.00
0.76
0.0
1.6
—
—
—
0
0
17
235
0.69
0.76
2.1
2.4
15.03
5.01
ug/l
—
10
191
87
957
0.85
0.66
3.7
4.2
52.12
95.36
ng/l
1.45
59
755
5
29
1.67
0.61
1.6
1.2
—
—
—
0
0
0
21
0.00
0.60
0.0
1.7
—
—
—
0
0
0
21
0.00
0.60
0.0
1.3
—
—
—
0
0
0
22
0.00
0.59
0.0
1.2
—
—
—
0
0
59
493
1.18
0.52
4.8
4.1
0.00
0.00
estimate
-0.00
14
149
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
1.0
—
—
—
0
0
0
16
0.00
0.41
0.0
1.0
—
—
—
0
0
0
17
0.00
0.40
0.0
1.4
—
—
—
0
0
0
18
0.00
0.39
0.0
1.3
—
—
—
0
0
0
18
0.00
0.39
0.0
5.0
—
—
—
0
0
0
18
0.00
0.39
0.0
1.1
—
—
—
0
0
0
18
0.00
0.39
0.0
1.3
—
—
—
0
0
5
34
1.42
0.39
1.6
1.2
—
—
—
0
0
5
35
1.38
0.38
1.6
1.3
12844.00
13028.88
e6/l
—
5
25
28
227
1.20
0.36
5.4
3.7
—
—
—
0
0
6
86
0.67
0.33
1.0
1.3
—
—
—
0
0
6
86
0.67
0.33
1.0
1.3
—
—
—
0
0
11
82
1.30
0.28
1.3
1.1
—
—
—
0
0
5
36
1.34
0.23
4.2
3.7
72.00
59.58
%
—
5
36
5
40
1.21
0.22
1.6
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.7
—
2.06
—
0
10
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.5
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.20
0.0
1.0
—
—
—
0
0
0
13
0.00
0.20
0.0
1.0
—
—
—
0
0
6
47
1.24
0.20
1.2
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
2.2
—
—
—
0
0
0
14
0.00
0.20
0.0
2.6
—
1.13
—
0
8
0
14
0.00
0.20
0.0
2.4
—
35.44
—
0
14
26
281
0.89
0.19
11.4
8.7
—
—
—
0
0
47
419
1.09
0.19
4.6
4.2
1.01
1.01
kg/l
0.08
11
87
9
76
1.15
0.15
1.7
1.6
—
—
—
0
0
76
742
0.99
0.01
4.9
4.6
—
—
—
0
0
18
176
0.99
0.00
1.7
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
283.20
—
0
5
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
1.17
—
0
5
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
18.42
—
0
5
0
5
0.00
0.00
0.0
1.2
—
8.20
—
0
5
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
9
0.00
-0.00
0.0
3.8
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
116.31
—
0
7
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
71.86
—
0
7
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
48.71
—
0
7
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
Mortality – FinRegistry
↥This endpoint is excluded (different definition than used in FinnGen).
Relationships between endpoints
↥Index endpoint: AD_U_EXMORE – Alzheimer’s disease (undefined), excluding more controls
GWS hits: 3
This endpoint is excluded (different definition than used in FinnGen).